CN112915185A

CN112915185A - Pharmaceutical composition and preparation method and application thereof

Info

Publication number: CN112915185A
Application number: CN202110157358.5A
Authority: CN
Inventors: 钟建飞
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-02-04
Filing date: 2021-02-04
Publication date: 2021-06-08

Abstract

The invention discloses a pharmaceutical composition, a preparation method and application thereof, and relates to the technical field of medicines. The pharmaceutical composition comprises the following components in parts by weight: lemon, honey, ginger, garlic and mature vinegar; the lemon, the honey, the ginger and the garlic are in mass ratio: lemon: and (3) honey: ginger: garlic 130-170: 3-7: 130-170; the mass-volume ratio of the lemon to the mature vinegar is as follows: lemon: and (3) mature vinegar 13-17: 50 g/mL. After the pharmaceutical composition is taken for a plurality of days, the symptoms of chest pain and chest distress can be obviously improved, the chest pressure is eliminated, the blood vessels are dredged, the curative effect is quick, and the risk is low.

Description

Pharmaceutical composition and preparation method and application thereof

Technical Field

The invention relates to the technical field of medicines, in particular to a pharmaceutical composition and a preparation method and application thereof.

Background

Chest pain is a very common disease, and chest pain is caused by work fatigue, disordered work and rest, cardiovascular diseases and the like. At present, the salvia miltiorrhiza dripping pills are generally used for treating symptoms such as chest pain, chest distress and the like caused by blood vessel blockage in clinic chest pain centers of hospitals, but the taking period is long, the curative effect is not obvious, the slight curative effect is achieved after the salvia miltiorrhiza dripping pills are generally taken for seven days, and the symptoms such as the chest distress, the chest pain and the like can relapse in a short period. In addition, the chest pain caused by cardiovascular diseases is usually treated by adopting a surgical operation method, and a stent is implanted into a human body to open blood vessels; however, the operation has certain risks, the audience is small and needs to take medicine for a long time, and the existence of the bracket can cause certain obstacles to the future life, physiology and psychology of the patient.

Disclosure of Invention

The invention aims to overcome the defects of the prior art and provides a pharmaceutical composition with quick response and good curative effect, a preparation method and application thereof.

In order to achieve the purpose, the technical scheme adopted by the invention is as follows: a pharmaceutical composition comprising the following ingredients: lemon, honey, ginger, garlic and mature vinegar; the lemon, the honey, the ginger and the garlic are in mass ratio: lemon: and (3) honey: ginger: garlic 130-170: 3-7: 130-170; the mass-volume ratio of the lemon to the mature vinegar is as follows: lemon: and (3) mature vinegar 13-17: 50 g/mL.

The lemon can regulate the permeability of blood vessels, prevent cardiovascular arteriosclerosis and reduce the viscosity of blood; the ginger can accelerate heartbeat and dilate blood vessels; bulbus Allii can prevent fat deposition in cardiovascular and cerebrovascular vessels, promote tissue fat metabolism, reduce cholesterol, lower blood concentration, promote vasodilatation, regulate blood pressure, promote blood circulation in blood vessel, inhibit thrombosis, and prevent arteriosclerosis; old vinegar can remove garbage in blood vessels; the applicant of the invention selects the proportion of the components, so that the prepared medicine composition has good effect of relieving chest pain and other symptoms caused by blood vessel blockage, and the taste of the medicine is improved by adding the honey into the components.

Preferably, the mass ratio of the lemon to the honey to the ginger to the garlic is 150:5:150: 150; the mass-volume ratio of the lemon to the mature vinegar is as follows: lemon: 15:50g/mL of mature vinegar.

Meanwhile, the invention also discloses a preparation method of the pharmaceutical composition, and equipment containing pig iron ingredients cannot be used in the preparation process of the pharmaceutical composition.

Preferably, the preparation method of the pharmaceutical composition comprises the following steps:

(1) crushing lemon, garlic and ginger into pulp, adding water, boiling, and preserving heat for 10-20 min to obtain a mixed solution A;

(2) filtering the mixed solution A to obtain a filtrate, adding mature vinegar and honey into the filtrate, extracting for 20-30 min, boiling with fast fire, and extracting with slow fire to obtain the pharmaceutical composition.

Preferably, the adding amount of the water in the step (1) is 40-60 vol.% of the adding amount of the mature vinegar in the step (2).

Further preferably, in the step (2), after boiling with fast fire, refining with slow fire for 25min to obtain the pharmaceutical composition.

In addition, the invention also discloses application of the pharmaceutical composition in dredging blood vessels and improving chest pain, chest distress and other diseases.

Compared with the prior art, the invention has the beneficial effects that: the raw materials of the pharmaceutical composition are common materials in life, the cost is low, patients can prepare the pharmaceutical composition at home, and the patients can keep normal daily work and activities during taking the pharmaceutical composition without side effects on human bodies. Compared with the conventional salvia miltiorrhiza dripping pill, the salvia miltiorrhiza dripping pill can take effect in a shorter time.

Detailed Description

To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.

Example 1

In an embodiment of the pharmaceutical composition of the present invention, the preparation method of the pharmaceutical composition of this embodiment is as follows:

pulverizing 150g of lemon, 150g of garlic and 150g of ginger into pulp by using a beater, pouring into a container without pig iron, adding 250mL of distilled water, boiling, preserving heat for 15 minutes, filtering, adding 5g of honey and 500mL of mature vinegar into filtrate, boiling with fast fire, and refining with slow fire for 25 minutes to obtain the pharmaceutical composition.

Comparative example 1

A pharmaceutical composition, the preparation method of the pharmaceutical composition is as follows:

crushing 100g of lemon, 180g of garlic and 170g of ginger into pulp by using a beater, pouring the pulp into a container without pig iron, adding 250mL of distilled water to boil, preserving heat for 15 minutes, filtering, adding 5g of honey and 500mL of mature vinegar into filtrate, boiling with fast fire, and refining with slow fire for 25 minutes to obtain the pharmaceutical composition.

Comparative example 2

pulverizing 150g of lemon, 150g of garlic and 150g of ginger into pulp by using a beater, pouring into a container without pig iron, adding 250mL of distilled water, boiling, preserving heat for 15 minutes, filtering, adding 5g of honey and 500mL of mature vinegar into filtrate, boiling with fast fire, and refining with slow fire for 40 minutes to obtain the pharmaceutical composition.

And (3) testing the drug effect:

6 adult patients with chest pain recently appeared were selected and divided into 3 groups of 2 patients, and the drug effects of example 1 and comparative examples 1 to 2 were evaluated.

The feedback results 3 days after administration and 1 month after completion of administration are shown in table 1, in which example 1 and comparative examples 1 to 2 were divided into 9 portions, and administered one portion each in the morning, in the middle of the day, and in the evening, for 3 days.

TABLE 1

As can be seen from table 1, the ratio of the lemon, the garlic, the ginger and the mature vinegar is selected, and the preparation time is controlled, so that the prepared pharmaceutical composition can eliminate chest pain of a patient within 3 days, and prevent the chest pain from recurring.

Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims

1. A pharmaceutical composition comprising the following components: lemon, honey, ginger, garlic and mature vinegar; the lemon, the honey, the ginger and the garlic are in mass ratio: lemon: and (3) honey: ginger: garlic 130-170: 3-7: 130-170; the mass-volume ratio of the lemon to the mature vinegar is as follows: lemon: and (3) mature vinegar 13-17: 50 g/mL.

2. The pharmaceutical composition according to claim 1, wherein the mass ratio of the lemon, the honey, the ginger and the garlic is 150:5:150: 150; the mass-volume ratio of the lemon to the mature vinegar is as follows: lemon: 15:50g/mL of mature vinegar.

3. A process for the preparation of a pharmaceutical composition according to any one of claims 1 to 2, wherein no equipment containing pig iron components is used in the preparation.

4. A process for preparing a pharmaceutical composition according to claim 3, comprising the steps of:

5. The method for preparing a pharmaceutical composition according to claim 4, wherein the water is added in an amount of 40 to 60 vol.% of the mature vinegar.

6. The method for preparing the pharmaceutical composition according to claim 5, wherein in the step (2), the pharmaceutical composition is obtained by boiling with fast fire and then refining with slow fire for 25 min.

7. The use of the pharmaceutical composition of any one of claims 1-2 for dredging blood vessels and improving chest pain and chest distress.