CN112870283A - A Chinese medicinal patch and its preparation method - Google Patents
A Chinese medicinal patch and its preparation method Download PDFInfo
- Publication number
- CN112870283A CN112870283A CN202110273550.0A CN202110273550A CN112870283A CN 112870283 A CN112870283 A CN 112870283A CN 202110273550 A CN202110273550 A CN 202110273550A CN 112870283 A CN112870283 A CN 112870283A
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- China
- Prior art keywords
- parts
- patch
- propolis
- plaster
- bee venom
- Prior art date
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Classifications
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- A61K36/18—Magnoliophyta (angiosperms)
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Landscapes
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Abstract
A Chinese medicinal patch is prepared from bee venom, propolis, herba Taraxaci, radix Puerariae, rhizoma Ligustici Chuanxiong, radix Clematidis, herba Speranskiae Tuberculatae, radix Angelicae sinensis, radix Tripterygii Wilfordii, sanguis Draxonis, semen Sinapis Albae, ramulus Cinnamomi, rhizoma corydalis, and caulis Spatholobi. The bee venom and the eucommia bark in the invention are used together with the ligusticum wallichii and the salvia miltiorrhiza to mainly counteract poison with poison, promote blood circulation to remove blood stasis, dispel wind and remove dampness. The plaster can be used for treating scapulohumeral periarthritis, cervical vertebra, waist and leg, sciatica and rheumatism, wherein the semen brassicae component can play a role in generating heat after contacting the skin without damaging the skin, and in addition, the propolis and the dandelion in the formula enable the plaster to achieve the effects of diminishing inflammation and resisting allergy, so that the phenomenon that most people are allergic to the plaster in the past is solved. Meanwhile, the product is used as an external application medicine patch, compared with the traditional black plaster, the medicine patch can be torn off and baked by fire, so that each medicine patch can be repeatedly used for 2-3 times.
Description
Technical Field
The invention relates to the field of medical patches, in particular to a traditional Chinese medicine composition patch and a preparation method thereof.
Background
The black plaster is an external preparation for being pasted on the skin by refining medicinal materials, edible vegetable oil and red lead to prepare a paste and spreading the paste on a backing material. It has protective, sealing and therapeutic effects, thick ointment layer, and long-lasting effect. The modern Chinese medicine is mainly a black plaster which is mainly used for promoting blood circulation to remove blood stasis and is externally applied to treat the diseases. The principle of treatment is conservative therapy, and it has been reported that about 90% of cases are cured by conservative therapy. Aiming at the conservative therapy, the traditional Chinese medicine can use a black plaster patch. However, the black plaster has limited effects and cannot be reused, so that the black plaster has limitations.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition patch and a preparation method thereof, and aims to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: a traditional Chinese medicine composition patch is prepared from the following raw material medicines in parts by weight:
1-3 parts of bee venom, 2-4 parts of propolis, 3-4 parts of dandelion, 3-4 parts of radix puerariae, 2-3 parts of ligusticum wallichii, 6-7 parts of radix clematidis, 2-3 parts of garden balsam stem, 2-4 parts of angelica, 1-2 parts of tripterygium wilfordii, 1-2 parts of dragon's blood, 1-2 parts of brassica juncea, 1-2 parts of cassia twig, 1-2 parts of rhizoma corydalis and 2-3 parts of caulis spatholobi.
A preparation method of a Chinese medicinal composition patch comprises the following steps:
1) taking bee venom, propolis, dandelion, kudzu root, ligusticum wallichii, radix clematidis, garden balsam stem, angelica, thunder god vine, dragon's blood, mustard seed, cassia twig, corydalis tuber and caulis spatholobi, drying the raw materials, and grinding into ultrafine powder of 800 meshes;
2) placing the superfine powder obtained in step 1) into a container, decocting at high temperature to obtain paste, cooling, and coating on medical non-woven fabric loaded in advance to obtain Chinese medicinal composition patch;
3) the Chinese medicinal composition patch in the step 2) can be repeatedly used for 2-3 times after being baked at high temperature after being used.
Preferably, the bee venom is pungent, bitter and mild in property. Bee venom has inhibitory effect on nervous system, and the Andreotide component in bee venom is an antagonist for prostate gland E, and has strong antiinflammatory and analgesic activities. (1) By inhibiting microsomal cyclooxygenase (prostaglandin synthetase), prostaglandin synthesis is inhibited. The effect of inhibiting brain cyclooxygenase is 70 times of that of indomethacin. (2) By binding with opioid receptors in the brain, analgesic action is exerted through the central nerve.
Preferably, the propolis is bitter, pungent and cold in nature. Invigorating spleen and stomach channels, tonifying asthenia, eliminating turbid urine, and quenching thirst; it is used externally to relieve swelling and remove toxicity. It can be used for treating asthenia, senilism, hyperlipidemia, and diabetes; it can be used for external treatment of chapped skin, burn and scald.
Preferably, the rhizoma ligustici wallichii, pungent, warm, fragrant and dry in flavor, is used for activating blood and promoting qi circulation, and dispelling wind and relieving pain. It is indicated for wind-cold headache, dizziness, hypochondriac pain, abdominal pain, cold arthralgia, spasm of tendons, amenorrhea, dystocia, postpartum pain due to blood stasis, carbuncle, cellulitis, sore and ulcer. Can be used for treating menoxenia, amenorrhea, dysmenorrhea, abdominal pain, pricking pain in chest and hypochondrium, traumatic injury, swelling and pain, headache, and rheumatalgia.
Preferably, the garden balsam stem has the effects of dispelling wind and removing dampness, promoting blood circulation and relieving pain, relaxing tendons and activating collaterals, and detoxifying and removing rash. Folk uses the whole herb as medicine to treat cold and traumatic injury, and externally treats carbuncle, eczema and scabies.
Preferably, the tripterygium wilfordii is bitter and cold in nature, has the effects of clearing heat and removing toxicity, dispelling wind and dredging collaterals, relaxing muscles and tendons and promoting blood circulation and the like, and is used for treating rheumatoid arthritis and nephritis.
Preferably, the clematis root is pungent, salty, warm and toxic; it enters bladder meridian. Has the effects of dispelling wind and eliminating dampness, dredging collaterals and relieving pain, eliminating phlegm and water and dispersing nodules. It is commonly used for stubborn arthralgia due to gout, arthralgia due to wind-dampness and numbness of limbs.
Preferably, the dragon's blood is pungent, salty, flat in flavor and slightly toxic. It is mainly used for dissipating blood stasis, relieving pain, stopping bleeding and promoting granulation. Treating traumatic injury, internal injury, blood stasis and pain; traumatic hemorrhage, scrofula and ecthyma for a long time.
Preferably, the corydalis tuber has the effects of activating blood circulation, promoting qi circulation and relieving pain, and is used for treating chest and hypochondrium pain, abdominal pain, chest stuffiness and pains, amenorrhea and dysmenorrhea, postpartum stasis and traumatic injury and swelling pain.
The bee venom and the eucommia bark in the invention are used together with the ligusticum wallichii and the salvia miltiorrhiza to mainly counteract poison with poison, promote blood circulation to remove blood stasis, dispel wind and remove dampness. The plaster can be used for treating scapulohumeral periarthritis, cervical vertebra, waist and leg, sciatica and rheumatism, wherein the semen brassicae component can play a role in generating heat after contacting the skin without damaging the skin, and in addition, the propolis and the dandelion in the formula enable the plaster to achieve the effects of diminishing inflammation and resisting allergy, so that the phenomenon that most people are allergic to the plaster in the past is solved. Meanwhile, the product is used as an external application medicine patch, compared with the traditional black plaster, the medicine patch can be torn off and baked by fire, so that each medicine patch can be repeatedly used for 2-3 times. After being pasted for 2-3 times, the waste plaster can be soaked in boiled water, and after the plaster is melted, the plaster is used for soaking feet, so that the effects of promoting blood circulation to remove blood stasis and treating dermatophytosis are achieved.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
A traditional Chinese medicine composition patch is prepared from the following raw material medicines in parts by weight:
1 part of bee venom, 4 parts of propolis, 4 parts of dandelion, 3 parts of kudzu root, 2 parts of ligusticum wallichii, 6 parts of radix clematidis, 2 parts of garden balsam stem, 2 parts of angelica, 2 parts of tripterygium wilfordii, 1 part of dragon's blood, 1 part of mustard seed, 1 part of cassia twig, 1 part of corydalis tuber and 3 parts of caulis spatholobi.
Example 2
A traditional Chinese medicine composition patch is prepared from the following raw material medicines in parts by weight:
2 parts of bee venom, 3 parts of propolis, 4 parts of dandelion, 3 parts of kudzu root, 2 parts of ligusticum wallichii, 7 parts of radix clematidis, 3 parts of garden balsam stem, 3 parts of angelica, 2 parts of tripterygium wilfordii, 2 parts of dragon's blood, 1 part of brassica juncea, 2 parts of cassia twig, 2 parts of corydalis tuber and 2 parts of caulis spatholobi.
Example 3
A traditional Chinese medicine composition patch is prepared from the following raw material medicines in parts by weight:
3 parts of bee venom, 2 parts of propolis, 3 parts of dandelion, 4 parts of kudzu root, 3 parts of ligusticum wallichii, 7 parts of radix clematidis, 3 parts of garden balsam stem, 4 parts of angelica, 1 part of tripterygium wilfordii, 2 parts of dragon's blood, 2 parts of brassica juncea, 1 part of cassia twig, 1 part of corydalis tuber and 2 parts of caulis spatholobi.
Example 4
A traditional Chinese medicine composition patch is prepared from the following raw material medicines in parts by weight:
2 parts of bee venom, 3 parts of propolis, 3 parts of dandelion, 3 parts of kudzu root, 3 parts of ligusticum wallichii, 7 parts of radix clematidis, 2 parts of garden balsam stem, 4 parts of angelica, 2 parts of tripterygium wilfordii, 2 parts of dragon's blood, 2 parts of brassica juncea, 2 parts of cassia twig, 1 part of corydalis tuber and 3 parts of caulis spatholobi.
The method for preparing the Chinese medicinal composition patches of the above embodiments 1-4 comprises the following steps:
1) taking bee venom, propolis, dandelion, kudzu root, ligusticum wallichii, radix clematidis, garden balsam stem, angelica, thunder god vine, dragon's blood, mustard seed, cassia twig, corydalis tuber and caulis spatholobi, drying the raw materials, and grinding into ultrafine powder of 800 meshes;
2) placing the superfine powder obtained in step 1) into a container, decocting at high temperature to obtain paste, cooling, and coating on medical non-woven fabric loaded in advance to obtain Chinese medicinal composition patch;
3) the Chinese medicinal composition patch in the step 2) can be repeatedly used for 2-3 times after being baked at high temperature after being used.
The clinical curative effect summary of the traditional Chinese medicine for treating scapulohumeral periarthritis, cervical vertebra, waist and leg, sciatica and rheumatism pathological changes symptoms comprises the following steps:
firstly, selecting diagnosis standards of cases:
1. scapulohumeral periarthritis: with pain around the shoulder joints, limited mobility and relief of symptoms over time.
2. Cervical vertebra pain: stiff neck, pain, weakness in upper limbs, numbness in fingers, even sudden dizziness and weakness, and dysphagia.
3. Lumbago: stiffness and persistent pain in the waist in the morning when getting up.
4. And (3) sciatica: pain is mainly caused in the sciatic nerve pathway and distribution area. Soreness of the lower back and stiffness of the waist. Or weeks before onset, with brief pain in the lower extremities while walking and exercising. And then gradually worsen and develop severe pain. Pain begins in the lumbar, hip or hip and spreads down the posterior aspect of the thigh, popliteal fossa, lateral aspect of the calf and dorsum of the foot, with a profuse array of burning or pin-prick-like pain on a persistent pain basis. More severe at night.
Second, examples 1-4 of the present invention were treated using the following treatment regimens: the prepared patch is applied to the selected acupuncture point once a day. The preparation is administered for 7 days for 1-4 treatment courses.
Examples 1-4 treatment using the following treatment protocol patches were selected that had been prepared and applied to selected acupuncture points once a day. The preparation is administered for 7 days for 1-4 treatment courses.
In addition, the patch can be baked for 2-3 times, and the waste plaster can be soaked in boiling water after application, and can be used for soaking feet after the plaster is melted, so as to promote blood circulation for removing blood stasis and treat tinea pedis.
Thirdly, 1, scapulohumeral periarthritis: using any one of the patches according to the treatment protocols of examples 1-4 of the present invention, the patch was applied to the selected acupoints once a day and once. 7 days is a course of treatment, 1-4 courses of treatment can be applied to the physical condition of a patient, and the evaluation standard of the curative effect is tracked and observed: and (3) healing: the symptoms completely disappear, and no uncomfortable symptoms exist; the method has the following advantages: the symptoms are obviously relieved, or part of symptoms disappear, and the treatment is needed to be continued; and (4) invalidation: the symptoms did not improve at all, but tended to be aggravated.
The results of clinical trials are shown in the following table:
after the patients in the table above pass through 4 treatment courses, the patients have no adverse reaction, and no abnormality is found in various liver and kidney function tests.
2. Cervical vertebra pain: using any one of the patches according to the treatment protocols of examples 1-4 of the present invention, the patch was applied to the selected acupoints once a day and once. 7 days is a course of treatment, 1-4 courses of treatment can be applied to the physical condition of a patient, and the evaluation standard of the curative effect is tracked and observed: and (3) healing: the symptoms completely disappear, and no uncomfortable symptoms exist; the method has the following advantages: the symptoms are obviously relieved, or part of symptoms disappear, and the treatment is needed to be continued; and (4) invalidation: the symptoms did not improve at all, but tended to be aggravated.
The results of clinical trials are shown in the following table:
after the patients in the table above pass through 4 treatment courses, the patients have no adverse reaction, and no abnormality is found in various liver and kidney function tests.
3. Lumbago: using any one of the patches according to the treatment protocols of examples 1-4 of the present invention, the patch was applied to the selected acupoints once a day and once. 7 days is a course of treatment, 1-4 courses of treatment can be applied to the physical condition of a patient, and the evaluation standard of the curative effect is tracked and observed: and (3) healing: the symptoms completely disappear, and no uncomfortable symptoms exist; the method has the following advantages: the symptoms are obviously relieved, or part of symptoms disappear, and the treatment is needed to be continued; and (4) invalidation: the symptoms did not improve at all, but tended to be aggravated.
The results of clinical trials are shown in the following table:
after the patients in the table above pass through 4 treatment courses, the patients have no adverse reaction, and no abnormality is found in various liver and kidney function tests.
4. And (3) sciatica: using any one of the patches according to the treatment protocols of examples 1-4 of the present invention, the patch was applied to the selected acupoints once a day and once. 7 days is a course of treatment, 1-4 courses of treatment can be applied to the physical condition of a patient, and the evaluation standard of the curative effect is tracked and observed: and (3) healing: the symptoms completely disappear, and no uncomfortable symptoms exist; the method has the following advantages: the symptoms are obviously relieved, or part of symptoms disappear, and the treatment is needed to be continued; and (4) invalidation: the symptoms did not improve at all, but tended to be aggravated.
The results of clinical trials are shown in the following table:
after the patients in the table above pass through 4 treatment courses, the patients have no adverse reaction, and no abnormality is found in various liver and kidney function tests.
The inventor has counted that the treatment effect of the embodiment 3 and the embodiment 4 is better, and the average curing time of 50 patients treated by the medical patches prepared in the embodiment 3 and the embodiment 4 is 12% shorter than that of the treatment scheme of the embodiment 1 and the embodiment 2.
Fourth, typical cases:
liu, 65 years old men and Wuhan Hubei suffer from scapulohumeral periarthritis for years, cannot turn around when sleeping at night, and cannot wear clothes when getting up in the morning. After the Chinese medicinal composition is applied to the patient for three days, the patient obviously feels that the arm is lifted easily, and all symptoms disappear after more than ten days. Half a year later return visits were without signs of recurrence.
Certain Liu, 74 years old by men, Hubei Xiantao people suffer from lumbar disc herniation and cause pain on the outer sides of both legs for many years, people need to squat for rest for five minutes to continue walking for ten minutes, people introduced by friends do not need to squat for rest for half an hour after walking for seven days after applying the traditional Chinese medicine composition, all symptoms disappear after continuous application for twenty times, and patients visit after one year without relapse.
Yellow certain, 45-year-old men and Hubei Xiantao people cannot sweep the floor, lift the pain and lift heavy objects for half a year due to tennis elbow which is a disease caused by frequent tennis play. The traditional Chinese medicine composition is obviously relaxed after being applied externally for three times, can be used for sweeping the floor at home, and has basic symptoms after being applied for ten times. There was no evidence of recurrence after half a year of return visits.
Somebody, 43 years old female, Chongqing, suffering from rheumatoid arthritis, wrist joint, knee joint deformation, pain, red swelling, stiffness, and early symptoms aggravate, and the temperature is slightly relieved after rising in the afternoon. Through introduction of friends, the Chinese medicinal composition external application is purchased for ten days, the early symptoms fed back by a patient after ten days are relieved, the patient feels comfortable when being applied with the Chinese medicinal composition for warming, and the Chinese medicinal composition is purchased for one month. After half a year the symptoms of telephone feedback largely disappeared with no signs of recurrence.
Wangzhi, female 25 years old, Hubei Yichang, twist the ankle while running, it is not relieved after home ice compress, can't walk in the lower reaches, the ankle is red and swollen, introduce from friend to apply the Chinese medicinal composition of the invention once in our place the next day, one comes to obviously subside swelling again the next day, can walk, basically recover after pasting twice, the patient's feedback has been completely good after five days.
A certain Liu is 65 years old for men, and New people in Henan province have had leg fractures, plaster is applied to a certain hospital, the fracture part becomes dull and does pain after the plaster is removed, the traditional Chinese medicine composition is applied to the new people through introduction five times, the patient does not have the symptom of the dull and does pain just the fifth time becomes the day, the patient takes five times to take the medicine home to consolidate, and the symptom of the dull and does pain fed back after one month does not relapse.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (4)
1. A traditional Chinese medicine composition patch is characterized by being prepared from the following raw materials in parts by weight:
1-3 parts of bee venom, 2-4 parts of propolis, 3-4 parts of dandelion, 3-4 parts of radix puerariae, 2-3 parts of ligusticum wallichii, 6-7 parts of radix clematidis, 2-3 parts of garden balsam stem, 2-4 parts of angelica, 1-2 parts of tripterygium wilfordii, 1-2 parts of dragon's blood, 1-2 parts of brassica juncea, 1-2 parts of cassia twig, 1-2 parts of rhizoma corydalis and 2-3 parts of caulis spatholobi.
2. The traditional Chinese medicine composition patch as claimed in claim 1, which is characterized in that the patch is prepared from the following raw materials in parts by weight: 3 parts of bee venom, 2 parts of propolis, 3 parts of dandelion, 4 parts of kudzu root, 3 parts of ligusticum wallichii, 7 parts of radix clematidis, 3 parts of garden balsam stem, 4 parts of angelica, 1 part of tripterygium wilfordii, 2 parts of dragon's blood, 2 parts of brassica juncea, 1 part of cassia twig, 1 part of corydalis tuber and 2 parts of caulis spatholobi.
3. The traditional Chinese medicine composition patch as claimed in claim 1, is characterized in that the patch is prepared from the following raw materials in parts by weight: 2 parts of bee venom, 3 parts of propolis, 3 parts of dandelion, 3 parts of kudzu root, 3 parts of ligusticum wallichii, 7 parts of radix clematidis, 2 parts of garden balsam stem, 4 parts of angelica, 2 parts of tripterygium wilfordii, 2 parts of dragon's blood, 2 parts of brassica juncea, 2 parts of cassia twig, 1 part of corydalis tuber and 3 parts of caulis spatholobi.
4. The method for preparing a Chinese medicinal composition patch as claimed in claim 1, comprising the steps of:
1) taking bee venom, propolis, dandelion, kudzu root, ligusticum wallichii, radix clematidis, garden balsam stem, angelica, tripterygium wilfordii, dragon's blood and brassica juncea, drying the medicinal raw materials, and grinding into 500-mesh and 800-mesh ultrafine powder;
2) placing the superfine powder obtained in step 1) into a container, decocting at high temperature to obtain paste, cooling, and coating on medical non-woven fabric loaded in advance to obtain Chinese medicinal composition patch;
3) the Chinese medicinal composition patch in the step 2) can be repeatedly used for 2-3 times after being baked at high temperature after being used.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113876745A (en) * | 2021-11-22 | 2022-01-04 | 长兴意蜂蜂业科技有限公司 | Bee venom bone penetrating therapy |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104383018A (en) * | 2014-09-22 | 2015-03-04 | 林军庭 | Lumbar degenerative pathological change treating traditional Chinese medicine composition plaster |
| CN108355005A (en) * | 2018-05-04 | 2018-08-03 | 中国科学院兰州化学物理研究所 | A kind of Chinese patent drug for treating the protrasion of the lumbar intervertebral disci |
-
2020
- 2020-04-16 CN CN202010298285.7A patent/CN111228380A/en not_active Withdrawn
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104383018A (en) * | 2014-09-22 | 2015-03-04 | 林军庭 | Lumbar degenerative pathological change treating traditional Chinese medicine composition plaster |
| CN108355005A (en) * | 2018-05-04 | 2018-08-03 | 中国科学院兰州化学物理研究所 | A kind of Chinese patent drug for treating the protrasion of the lumbar intervertebral disci |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113876745A (en) * | 2021-11-22 | 2022-01-04 | 长兴意蜂蜂业科技有限公司 | Bee venom bone penetrating therapy |
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