CN112773764A - Nasal care lotion - Google Patents
Nasal care lotion Download PDFInfo
- Publication number
- CN112773764A CN112773764A CN201911093391.5A CN201911093391A CN112773764A CN 112773764 A CN112773764 A CN 112773764A CN 201911093391 A CN201911093391 A CN 201911093391A CN 112773764 A CN112773764 A CN 112773764A
- Authority
- CN
- China
- Prior art keywords
- nasal
- water
- sodium hyaluronate
- percentage
- mucosa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000006210 lotion Substances 0.000 title description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 22
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 11
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 10
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 10
- 235000016887 Leptospermum scoparium Nutrition 0.000 claims abstract description 8
- 240000003553 Leptospermum scoparium Species 0.000 claims abstract description 8
- 235000012907 honey Nutrition 0.000 claims abstract description 8
- 239000001140 aloe barbadensis leaf extract Substances 0.000 claims abstract description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 15
- HHVIBTZHLRERCL-UHFFFAOYSA-N sulfonyldimethane Chemical compound CS(C)(=O)=O HHVIBTZHLRERCL-UHFFFAOYSA-N 0.000 claims description 10
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims description 5
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims description 5
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 5
- 239000004302 potassium sorbate Substances 0.000 claims description 5
- 229940069338 potassium sorbate Drugs 0.000 claims description 5
- 235000010241 potassium sorbate Nutrition 0.000 claims description 5
- 239000001509 sodium citrate Substances 0.000 claims description 5
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 5
- 239000000811 xylitol Substances 0.000 claims description 5
- 235000010447 xylitol Nutrition 0.000 claims description 5
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims description 5
- 229960002675 xylitol Drugs 0.000 claims description 5
- 210000002850 nasal mucosa Anatomy 0.000 abstract description 10
- 230000000694 effects Effects 0.000 abstract description 3
- 230000008952 bacterial invasion Effects 0.000 abstract description 2
- 238000012423 maintenance Methods 0.000 abstract description 2
- 230000004682 mucosal barrier function Effects 0.000 abstract description 2
- 210000003928 nasal cavity Anatomy 0.000 description 24
- 239000008213 purified water Substances 0.000 description 4
- 230000008439 repair process Effects 0.000 description 4
- 230000001954 sterilising effect Effects 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- 235000011399 aloe vera Nutrition 0.000 description 3
- 230000003020 moisturizing effect Effects 0.000 description 3
- 210000001331 nose Anatomy 0.000 description 3
- 206010039083 rhinitis Diseases 0.000 description 3
- 235000002639 sodium chloride Nutrition 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 2
- 241001116389 Aloe Species 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 229920002674 hyaluronan Polymers 0.000 description 2
- 229960003160 hyaluronic acid Drugs 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 235000002961 Aloe barbadensis Nutrition 0.000 description 1
- 244000186892 Aloe vera Species 0.000 description 1
- 206010003399 Arthropod bite Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- 206010052437 Nasal discomfort Diseases 0.000 description 1
- 206010028740 Nasal dryness Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 210000004381 amniotic fluid Anatomy 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- -1 dextran aldehyde Chemical class 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 210000005260 human cell Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000003434 inspiratory effect Effects 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 210000001989 nasopharynx Anatomy 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 206010041232 sneezing Diseases 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
Abstract
The invention discloses a nasal care solution, which comprises the following components in percentage by weight: 2-4% of manuka honey, 9-11% of active sodium hyaluronate and 3-6% of aloe leaf extract. The nasal protection water contains natural components, has long-acting maintenance, replenishes water to nasal mucosa to solve essential problems, establishes a mucosal barrier, resists bacterial invasion, integrates three effects into one, and is physically safe.
Description
Technical Field
The invention relates to the field of nasal health care and nursing, in particular to nasal care lotion.
Background
The dry nasal mucosa can cause multiple rhinitis problem, especially when weather is dry, the moisture loss in the nasal cavity is more to present haze weather is frequent, and the inspiratory haze of nose is many, and the phenomenon that the dry sense of nasopharynx can appear in the people, often can lead to nasal cavity and oral mucosa surface dry. The nasal cavity is dry, nasal secretion is reduced, itching feeling or foreign body feeling in the nasal cavity often causes sneezing and burning feeling, the nasal cavity is ulcerated and scabbed, and the scabbed is removed and easy to bleed. Causing great pain to people.
At present, the traditional rhinitis spray containing hormone is available on the market, has temporary relief, dependence and poor safety; in addition, the traditional sea salt spray is characterized in that sea salt is excessively used, the more the sea salt is cleaned and dried, the nasal mucosa is damaged, and products for solving essential problems are not common.
Disclosure of Invention
The invention aims to provide the nasal protection water which is an SPA for moisturizing nasal cavities, is used for sterilizing the nasal cavities, moisturizing the nasal cavities at high permeability, deeply repairing nasal mucosa, and solving the problems that nasal dryness, nasal itching, excessive internal heat and the like easily cause the nasal cavities, and severe rhinitis sicca and atrophic and the like.
The specific technical scheme of the invention is as follows:
the invention provides a nasal care solution, which comprises the following components in percentage by weight: 2-4% of manuka honey, 9-11% of sodium hyaluronate and 3-6% of aloe leaf extract.
Preferably, the sodium hyaluronate is active sodium hyaluronate.
Preferably, the nasal care solution further comprises the following components in percentage by weight: 78-80% of water, 0.1-0.3% of dimethyl sulfone, 1-3% of xylitol, 0.05-0.25% of citric acid, 0.01-0.2% of sodium citrate and 0.1-0.3% of potassium sorbate.
Preferably, the water is purified water.
The manuka honey disclosed by the invention is pure new zealand manuka honey, is safe in sterilization and oxidation resistance, is used for nasal cavity sterilization, contains rich nutrients, can diminish inflammation and inhibit bacteria, prevents infection and promotes healing, has strong and unique antibacterial and oxidation resistance, better repairs and damages nasal mucosa, recovers normal physiological functions of the nasal cavity, more actively promotes healing of damaged skin, effectively repairs damage in the nasal cavity, improves the resistance of the nose, and strongly resists stimulation of external haze, dust, pollen, flying wadding, dry and cold air and the like, so that the nose is not sensitive.
The active sodium hyaluronate adopted by the invention is a dextran aldehyde acid, is used for nasal cavity high-permeability water replenishing, is widely present in human placenta, amniotic fluid and other parts, and has lubricating and nourishing effects on human cells; meanwhile, the micro-environment of cell metabolism is provided, and the moisturizing and conducting functions of the nasal mucosa are maintained. Triple hyaluronic acid is introduced into the nasal cavity, the water channel of the nasal cavity is internally and externally activated, the water-deficient nasal source is positioned and induced, and the absorption, repair and vitality promotion are improved. Three water-locking molecules are externally combined and are introduced in a triple mode: the micromolecular hyaluronic acid quickly permeates nasal cavities to replenish water and fully nourish the deep part of water shortage; the middle molecular sodium hyaluronate can freely flow into the nasal cavity and dry the inner layer of the nasal cavity, so that the nasal cavity can be drunk with full water at a large mouth; the macromolecular sodium hyaluronate forms a water locking film on the epidermis, and the inside and the outside of the water locking film are combined to retain water.
The aloe leaves adopted by the invention are aloe barbadensis leaf extracts and are used for repairing nasal cavities and connecting and repairing nasal mucosa, and precious mucin in aloe is used for repairing and connecting damaged nasal mucosa to form a protective film in the nasal cavities; the mucin acts on nasal cavity cell mucosa to make nasal mucosa tissue have elasticity; the mucin can form a protective film to keep the water in nasal cavity from diffusing.
Compared with the prior art, the invention has the advantages that:
1) the nasal protection water contains natural components, has long-acting maintenance, replenishes water to nasal mucosa to solve essential problems, establishes a mucosal barrier, resists bacterial invasion, integrates three effects into one, and is physically safe.
2) The nasal protecting water has mild components, no limitation on spraying frequency, and can nourish and clean nasal cavity. It can be used for children, adults, and the elderly.
3) The nasal care lotion can also be used for oral sterilization, mosquito bite, after-sun repair, acne removal, inflammation diminishing and the like.
Detailed Description
The present invention will be further described with reference to the following specific examples.
Example 1
The nasal care solution comprises the following components in percentage by weight: 3% of manuka honey, 10% of active sodium hyaluronate, 5% of aloe leaf extract, 79.35% of purified water, 0.2% of dimethyl sulfone, 2% of xylitol, 0.15% of citric acid, 0.1% of sodium citrate and 0.2% of potassium sorbate.
Example 2
The nasal care solution comprises the following components in percentage by weight: 4% of manuka honey, 9% of active sodium hyaluronate, 5% of aloe leaf extract, 78.35% of purified water, 0.1% of dimethyl sulfone, 3% of xylitol, 0.15% of citric acid, 0.1% of sodium citrate and 0.3% of potassium sorbate.
Example 3
The nasal care solution comprises the following components in percentage by weight: 3.5% of manuka honey, 9.5% of active sodium hyaluronate, 5.5% of aloe leaf extract, 79.25% of purified water, 0.2% of dimethyl sulfone, 1.5% of xylitol, 0.25% of citric acid, 0.2% of sodium citrate and 0.1% of potassium sorbate.
The method for preparing the nasal care solution can adopt the conventional preparation method in the field.
Conventional technical knowledge in the art can be used for the details which are not described in the present invention.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and are not limited. Although the present invention has been described in detail with reference to the embodiments, it will be understood by those skilled in the art that various changes may be made and equivalents may be substituted without departing from the spirit and scope of the invention as defined in the appended claims.
Claims (2)
1. The nasal care solution is characterized by comprising the following components in percentage by weight: 2-4% of manuka honey, 9-11% of sodium hyaluronate and 3-6% of aloe leaf extract.
2. The nasal wash of claim 1, further comprising, in weight percent: 78-80% of water, 0.1-0.3% of dimethyl sulfone, 1-3% of xylitol, 0.05-0.25% of citric acid, 0.01-0.2% of sodium citrate and 0.1-0.3% of potassium sorbate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911093391.5A CN112773764A (en) | 2019-11-11 | 2019-11-11 | Nasal care lotion |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911093391.5A CN112773764A (en) | 2019-11-11 | 2019-11-11 | Nasal care lotion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112773764A true CN112773764A (en) | 2021-05-11 |
Family
ID=75749599
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911093391.5A Pending CN112773764A (en) | 2019-11-11 | 2019-11-11 | Nasal care lotion |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112773764A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113730337A (en) * | 2021-10-26 | 2021-12-03 | 中盐工程技术研究院有限公司 | Nasal cavity cleaning fluid and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102245190A (en) * | 2008-10-14 | 2011-11-16 | 蜜钮康新西兰有限公司 | Antimicrobial compositions |
| CN103120703A (en) * | 2013-01-06 | 2013-05-29 | 王峥 | Care solution for cleaning nasal cavity and related composition |
| CN105658281A (en) * | 2013-01-14 | 2016-06-08 | 三重创新公司 | Honey nasal rinse |
| CN109846985A (en) * | 2019-02-28 | 2019-06-07 | 浙江朗柯生物工程有限公司 | A kind of nasal cavity disease adjuvant treatment cleaning agent and preparation method thereof |
| CN110279656A (en) * | 2019-07-11 | 2019-09-27 | 温州医科大学 | A kind of composition for alleviating mycteroxerosis and preparation method thereof and application method |
-
2019
- 2019-11-11 CN CN201911093391.5A patent/CN112773764A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102245190A (en) * | 2008-10-14 | 2011-11-16 | 蜜钮康新西兰有限公司 | Antimicrobial compositions |
| CN103120703A (en) * | 2013-01-06 | 2013-05-29 | 王峥 | Care solution for cleaning nasal cavity and related composition |
| CN105658281A (en) * | 2013-01-14 | 2016-06-08 | 三重创新公司 | Honey nasal rinse |
| CN109846985A (en) * | 2019-02-28 | 2019-06-07 | 浙江朗柯生物工程有限公司 | A kind of nasal cavity disease adjuvant treatment cleaning agent and preparation method thereof |
| CN110279656A (en) * | 2019-07-11 | 2019-09-27 | 温州医科大学 | A kind of composition for alleviating mycteroxerosis and preparation method thereof and application method |
Non-Patent Citations (1)
| Title |
|---|
| VICTORIA S. LEE，等: "Manuka honey sinus irrigation for the treatment of chronic rhinosinusitis: a randomized controlled trial", 《INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113730337A (en) * | 2021-10-26 | 2021-12-03 | 中盐工程技术研究院有限公司 | Nasal cavity cleaning fluid and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR101584824B1 (en) | Osmolyte-containing Preparation for the Treatment of Dry Mucous Membranes | |
| US9050351B2 (en) | Topical compositions designed to maintain or restore the integrity of the mucous membranes | |
| EP2251016B1 (en) | Topical use of hyaluronic acid with filmogenic action for the treatment and prophylaxys of pathologies of the respiratory tract. | |
| CN105107007A (en) | Cationic medical wound protecting dressing and method for preparing same | |
| CN109394837A (en) | A kind of nasal mist and preparation method thereof | |
| CN112773764A (en) | Nasal care lotion | |
| CN108379139B (en) | Toothpaste for preventing and treating dental ulcer and preparation method and application thereof | |
| CN105381454B (en) | A kind of nasal cavity wetting agent containing trehalose | |
| CN112055594A (en) | Liquid composition for treating mucosa of oropharyngeal laryngeal tract | |
| CN113081916A (en) | A toothpaste containing horse chestnut extract for periodontal repair | |
| CN105412913B (en) | A kind of nasal cavity wetting agent | |
| CN108992364B (en) | Moisturizing facial cleanser containing sodium lauroyl glutamate | |
| Ara et al. | Use of apitherapy as a novel practice in the management of oral diseases: A review of literature | |
| EP3656370A1 (en) | Pharmaceutical composition and its use for the prevention and treatment of oral cavity pathologies | |
| CN107982300B (en) | Spray and preparation method and application thereof | |
| CN114159500A (en) | Hyaluronic acid essential oil composition for nourishing and repairing oral cavity and application thereof | |
| KR101049402B1 (en) | Manufacturing method of bathing material for improving atopic dermatitis, bathing material for improving atopic dermatitis manufactured by the same and soap comprising the same | |
| CN113786371A (en) | Composition for preparing blueberry seaweed mask, mask and preparation method | |
| CN112402356A (en) | Pure micro-ecological skin cooling and nursing mask containing Chinese herbal medicines | |
| CN112516158B (en) | Composition for treating pharyngitis and preparation method thereof | |
| CN111821368A (en) | Composition for treating rhinitis and rhinitis ointment containing composition | |
| WO2023168020A1 (en) | Treatment composition for nasal and oral dryness, nosebleeds, and allergy symptoms | |
| CN109044898A (en) | A kind of hemostasis oral cavity nursing agent of brilliant white fresh breath type | |
| CN108309818A (en) | Whitening cosmetics | |
| JP2723473B2 (en) | Uses of sulfated saccharides |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210511 |