CN108309818A - Whitening cosmetics - Google Patents

Whitening cosmetics Download PDF

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Publication number
CN108309818A
CN108309818A CN201810234521.1A CN201810234521A CN108309818A CN 108309818 A CN108309818 A CN 108309818A CN 201810234521 A CN201810234521 A CN 201810234521A CN 108309818 A CN108309818 A CN 108309818A
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China
Prior art keywords
parts
whitening cosmetics
whitening
skin
weight
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CN201810234521.1A
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Chinese (zh)
Inventor
谢真
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Shenzhen Lingdu Intelligent Control Technology Co Ltd
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Shenzhen Lingdu Intelligent Control Technology Co Ltd
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Priority to CN201810234521.1A priority Critical patent/CN108309818A/en
Publication of CN108309818A publication Critical patent/CN108309818A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/362Polycarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists

Abstract

The present invention discloses a kind of whitening cosmetics, and by weight, which includes:3~8 parts of collagen protein powder, 3~5 parts of vitamin E, 5~10 parts of azelaic acid derivant, 0.5~1.5 part of curcumin, 3~5 parts of dipotassium glycyrrhizinate, 3~10 parts of cetostearyl alcohol, 2~5 parts of dimethicone, 10~15 parts of white oil, 0.1~0.5 part of Marjoram essential oil, 0.1~0.5 part of tea tree ethereal oil, 0.1~0.5 part of lemon, 0.5~1 part of preservative, 5~20 parts of moisturizer, 50 60 parts of deionized water.A kind of whitening patch-lightening cosmetic that technical solution of the present invention provides has preferable antibacterial, anti-oxidant, whitening, nti-freckle and moistening effect.

Description

Whitening cosmetics
Technical field
The present invention relates to cosmetic technical field, more particularly to a kind of whitening cosmetics.
Background technology
Melanin (melanin) is an important factor for determining human body complexion, it is in basal layer of epidermis melanocyte Biosynthesis in melanosome.Under normal physiological condition, melanin can protect the skin from uv damage in skin.When outer When portion's infringement, hormonal imbalance, aging or other factors cause B16 cell metabolic mechanism obstacle, easily make the black of basal layer of epidermis Hyperpigmentation, part or whole skin color and luster are deepened, and the pigments such as freckle, chloasma, cyasma, senile plaque, melanoma are caused Calm class skin disease, affects the appearance of people.The biosynthesis step of melanin is:The junket being present in melanocyte tissue Propylhomoserin is converted into DOPA under the action of tyrosinase, and DOPA continuation is converted into DOPA quinone, DOPA under the catalysis of tyrosinase Quinone continues to be converted into dopachrome, 5,6- dihydroxy indoles, 5,6- istains, is finally changed into melanin.Melanin granule closes It is sent in horn cell by dendrite at rear.
Azelaic acid, popular name azalaic acid, it can inhibit the albumen of cell to synthesize, also can emulative inhibition tyrosinase, It is widely used, but azelaic acid is insoluble in water and oil, is making up in dermatologic as a kind of antiseptic of external application It is difficult to directly add in product, and azelaic acid has stimulation, sucking or intake pair to skin, eyes, mucous membrane and the upper respiratory tract Body is harmful.Also have in cosmetic field and azelaic acid is modified as the product of azelaic acid Diglycocol potassium salt soln or uses it His azelaic acid derivant, but its use has also suffered from limitation.
Curcumin has the formation, antiviral and anti-that multiple biological activities are for example anti-oxidant, remove free radical, inhibit melanin Therefore inflammation etc. has been reported that and it is applied in functional cosmetics both at home and abroad, such as whitening product, anti-inflammatory products and sun-proof anti- Wrinkle product etc..
It is individually used in cosmetics, especially nti-freckle, skin-lightening cosmetic about azelaic acid and its derivative, curcumin Have relevant report, but has no and be provided commonly for azelaic acid derivant and curcumin to prepare whitening and freckle-removing product.
Invention content
The main object of the present invention is to propose a kind of whitening cosmetics, which has preferable anti- Bacterium, anti-oxidant, whitening, nti-freckle and moistening effect.
To achieve the above object, the present invention proposes a kind of whitening cosmetics, by weight, whitening spot-removing makeup Product include:3~8 parts of collagen protein powder, 3~5 parts of vitamin E, 5~10 parts of azelaic acid derivant, 0.5~1.5 part of curcumin, 3~5 parts of dipotassium glycyrrhizinate, 3~10 parts of hexadeca-octadecyl alcohol, 2~5 parts of dimethicone, 10~15 parts of white oil, Marjoram essential oil 0.1~0.5 part, 0.1~0.5 part of tea tree ethereal oil, 0.1~0.5 part of lemon, 0.5~1 part of preservative, moisturizer 5~20 Part, 50-60 parts of deionized water.
Preferably, by weight, the whitening cosmetics include:5~6 parts of collagen protein powder, vitamin E 3~ 4 parts, 6~8 parts of azelaic acid derivant, 1.0~1.5 parts of curcumin, 4~5 parts of dipotassium glycyrrhizinate, 5~8 parts of hexadeca-octadecyl alcohol, two 2~4 parts of methyl-silicone oil, 10~15 parts of white oil, 0.4~0.5 part of Marjoram essential oil, 0.3~0.4 part of tea tree ethereal oil, lemon 0.3~0.4 part, 0.6~0.8 part of preservative, 10~15 parts of moisturizer, 50-60 parts of deionized water.
Preferably, the whitening cosmetics further include the vitamin C derivatives that parts by weight are 5~10 parts.
Preferably, the whitening cosmetics further include the azone that parts by weight are 0.5~1.5 part.
Preferably, the whitening cosmetics further include the titanium dioxide that parts by weight are 0.3~0.4 part.
Preferably, the whitening cosmetics further include the antioxidant that parts by weight are 0.1~0.5 part.
Preferably, the preservative includes ethylparaben and/or imidazolidinyl urea.
Preferably, the moisturizer includes hyaluronic acid, glycerine, glycerine, butanediol, polyethylene glycol, xylitol, poly- third One or more compositions in glycol, D-sorbite.
In the whitening cosmetics that technical solution of the present invention provides, azelaic acid derivant has aerobic and anaerobic bacteria anti- Bacterium activity, while high-activity black chromatophore is may also suppress, there is anti-proliferative effect to the formation of horn cell, has no toxic side effect; Curcumin can effectively remove the free radical in skin, while can also have obvious inhibiting effect to tyrosinase, thus energy Mitigate the calmness of skin pigment, and curcumin also has preferable anti-oxidant, antiviral and anti-inflammatory effect;Moisturizer is to flesh Skin water is adjusted, and skin is made to soak, and has gloss and elasticity.
Specific implementation mode
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is general The every other embodiment that logical technical staff is obtained without creative efforts belongs to what the present invention protected Range.
In addition, the technical solution between each embodiment can be combined with each other, but must be with ordinary skill Personnel can be implemented as basis, will be understood that this technical side when the combination of technical solution appearance is conflicting or cannot achieve The combination of case is not present, also not the present invention claims protection domain within.
The present invention proposes a kind of whitening cosmetics, has preferable antibacterial, anti-oxidant, whitening, nti-freckle and moisturizing Effect.Wherein, the whitening cosmetics can be solution, suspension, emulsion, creme, ointment, gel, milk, Any one of powder, perfumed soap, oil, dry powder, foundation emulsion, wet-milling or spray form.
Whitening cosmetics proposed by the present invention, by weight, which includes:Collagen protein powder 3~8 parts, 3~5 parts of vitamin E, 5~10 parts of azelaic acid derivant, 0.5~1.5 part of curcumin, 3~5 parts of dipotassium glycyrrhizinate, 3~10 parts of hexadeca-octadecyl alcohol, 2~5 parts of dimethicone, 10~15 parts of white oil, 0.1~0.5 part of Marjoram essential oil, tea tree essence 0.1~0.5 part of oil, 0.1~0.5 part of lemon, 0.5~1 part of preservative, 5~20 parts of moisturizer, 50-60 parts of deionized water.
Preferably, by weight, the whitening cosmetics include:5~6 parts of collagen protein powder, vitamin E 3~ 4 parts, 6~8 parts of azelaic acid derivant, 1.0~1.5 parts of curcumin, 4~5 parts of dipotassium glycyrrhizinate, 5~8 parts of hexadeca-octadecyl alcohol, two 2~4 parts of methyl-silicone oil, 10~15 parts of white oil, 0.4~0.5 part of Marjoram essential oil, 0.3~0.4 part of tea tree ethereal oil, lemon 0.3~0.4 part, 0.6~0.8 part of preservative, 10~15 parts of moisturizer, 50-60 parts of deionized water.
Collagen protein powder is added in the whitening cosmetics, the polypeptide in collagen protein powder can inhibit tyrosinase Activity, reduce the formation of color spot, and collagen has unique repair to skin, mutually tied with the cell tissue of surrounding It closes, effectively facilitates Skin Cell regeneration, repair the acne print acne scar of epidermis, and micromolecular collagen is as a kind of effectiveization Cosmetic raw material can accomplish moisturizing, assign skin and smoothly feel.
Vitamin E is added in the whitening cosmetics, can effectively remove the free radical in skin, while can also be right Tyrosinase has obvious inhibiting effect, therefore and mitigates cutaneous pigmentation.
Marjoram essential oil, tea tree ethereal oil, lemon are added in the whitening cosmetics, wherein Marjoram essential oil Inoxidizability is strong, can promote skin blood circulation, promoting blood circulation and removing obstruction in channels, relieves pain, and having improves greasy, acne, unclean flesh The effect of skin, Kohakuhi and acne print.Tea tree ethereal oil is the blade of tea tree and tender tip is raw material, is carried using vapor distillation method It takes, can quickly see through hair follicle, have the function of sterilization, anti-inflammatory purifying skin.Lemon can remove old dead cell, and become clear skin Color, consolidation capilary promote collagen to generate, and desalinate melanin, have the effect of purification to greasy hair skin, can soften and scab Tissue;Improve oily skin, there is clean skin, convergence, Bergamot Mint Extract, skin whitening.
Preservative is added in the whitening cosmetics, antibacterial and sterilization can be played the role of.The preservative packet Include ethylparaben and/or imidazolidinyl urea.Isothiazolinone can to bacterium, fungi, algae etc. have it is very strong inhibition and Killing effect, function and effect are excellent;Methyl hydroxybenzoate can make intracellular albumen qualitative change by the cell membrane of destruction microorganism Shape, to inhibit the growth of bacterium colony.
Moisturizer is added in the whitening cosmetics, dry skin shape body can be improved, hence it is evident that improve skin Water content increases skin elasticity, and can also prevent skin damage and promote damaged skin reparation.Specifically, the moisturizer Including one kind in hyaluronic acid, glycerine, glycerine, butanediol, polyethylene glycol, xylitol, polypropylene glycol, D-sorbite or more Kind composition.Hyaluronic acid is the important component of generally existing in intercellular matrix, it fills the sky between various histocytes Between, most important function is that the ability of moisture is kept in intercellular matrix in terms of hyaluronan molecule biology, is important Moisturizer raw material;Glycerine has good moisturizing and nourishing effect, can absorb extraneous moisture, keep the water of skin tender;D- is general Alcohol can make the moisturizer that the nursing role on skin shows as penetrating deep into, and stimulate the growth of epithelial cell, promote wound healing, Play antiinflammation.
In a preferred embodiment, the whitening cosmetics further include that the vitamin C that parts by weight are 5~10 parts spreads out Biology.Vitamin C derivatives can decompose via the enzyme systems inside skin after percutaneous absorption and be reduced to vitamin C, Vitamin C derivatives not only remain ascorbic physiological activity, but also improve ascorbic unstable characteristic and skin Not absorbability, skin base layer can be penetrated into moment, not oxidizable, stability is high, safe and non-stimulating, and the dimension life after restoring Plain C can be reduced directly melanin, and melanin is reduced to colourless reduced form melanin, to reach skin whitening, desalination The effect of color spot, but because the melanin through reduction may still be aoxidized again, therefore U.S. that vitamin C derivatives are functional component White product, it is necessary to keep enough concentration and adhere to that use can be only achieved effect for a long time, and vitamin C derivatives can also lead to The antioxidant activity of itself is crossed, o-quinone is restored, and inhibits the activity of catalase to reach inhibition melanin production The effect of;On the one hand the addition of vitamin E can prevent ultraviolet light and pollute the injury to skin of air, promote the new of skin Old metabolism prevents pigment deposition, improves skin elasticity, moisturizes the skin, and on the other hand promotes skin metabolism that can prevent color The deposition of element improves skin elasticity, moisturizes the skin, plays beauty, skin care, anti-aging effect.
The vitamin C derivatives include L-Ascorbic Acid L-O-Phosphate salt, vitamin C glucoside, Vitamin C Ethyl Ether In one kind.
L-Ascorbic Acid L-O-Phosphate is a kind of odorless, tasteless powder, into human body after rapidly enzymolysis be in vitamin C, be not easy It aoxidizes, be not afraid of alkali, do not influenced by metal ions such as iron, it can long term storage;Vitamin C glucoside on 2 due to having grape Sugar masking, will not occur ascorbic oxidation reaction, have oxidation stability in vitro, into organism, in epidermis With vitamin C can be slowly decomposited under the action of a- glucuroides existing for intradermal, this slow releasing function substantially prolongs Ascorbic action time improves the effect of whitening;Vitamin C Ethyl Ether is by hydroxyl second on ascorbic position 3 Oxygen groups replace, and can effectively prevent product discoloration with ethoxy group substituted hydroxy, improve product stability, while improving dimension life The stability of plain C and inoxidizability in water, in addition Vitamin C Ethyl Ether is the hydrophilic both sexes vitamin C derivatives of oleophylic, So easy to use in component, and the property of both sexes is that Vitamin C Ethyl Ether is easier to penetrate cuticula and enters skin corium, To play its biological effectiveness.
Further, the whitening cosmetics further include the azone that parts by weight are 0.5~1.5 part.Azone is one Kind of the nontoxic skin penetration enhancer of highly effective and safe, to hydrophilic and oleophylic medicine have it is apparent it is transdermal help the effect of oozing, in emulsion or Under colloidal state all the effect of oozing is helped with good
The whitening cosmetics further include the titanium dioxide that parts by weight are 0.3~0.4 part.Ultraviolet light has human body Prodigious harm, titanium dioxide are white, and chemical property is stable, nontoxic, neutral, and nano-titanium dioxide is inorganic constituents, With excellent chemical stability, thermal stability and non-migratory and stronger reducing power, covering power, and nano-titanium dioxide Technical ability absorb ultraviolet light can emit again, scatters ultraviolet, therefore anti-ultraviolet ability is strong, and thinner because of particle, is made Product transparency is high, can penetrate visible light, skin whiteness is natural when being applied in cosmetics, the organic matter or pigment-level overcome Opaque, the pale asphyxia defect for keeping skin appearance not natural of titanium dioxide.
The whitening cosmetics further include the antioxidant that parts by weight are 0.1~0.5 part.
In the whitening cosmetics that technical solution of the present invention provides, azelaic acid derivant has aerobic and anaerobic bacteria anti- Bacterium activity, while high-activity black chromatophore is may also suppress, there is anti-proliferative effect to the formation of horn cell, has no toxic side effect; Curcumin can effectively remove the free radical in skin, while can also have obvious inhibiting effect to tyrosinase, thus energy Mitigate the calmness of skin pigment, and curcumin also has preferable anti-oxidant, antiviral and anti-inflammatory effect;Moisturizer is to flesh Skin water is adjusted, and skin is made to soak, and has gloss and elasticity.
Technical scheme of the present invention is further elaborated below in conjunction with specific embodiment.
Embodiment 1:
A kind of whitening cosmetics, by weight, which includes:3 parts of collagen protein powder, dimension life 3 parts of plain E, 5 parts of azelaic acid derivant, 0.5 part of curcumin, 3 parts of dipotassium glycyrrhizinate, 3 parts of hexadeca-octadecyl alcohol, dimethicone 2 Part, 10 parts of white oil, 0.1 part of Marjoram essential oil, 0.1 part of tea tree ethereal oil, 0.1 part of lemon, 0.5 part of preservative, moisturizer 5 Part, 50 parts of deionized water.
Wherein, the preservative is ethylparaben, and the moisturizer is hyaluronic acid.
Embodiment 2:
A kind of whitening cosmetics, by weight, which includes:5 parts of collagen protein powder, dimension life 4 parts of plain E, 6 parts of azelaic acid derivant, 1.0 parts of curcumin, 4 parts of dipotassium glycyrrhizinate, 5 parts of hexadeca-octadecyl alcohol, dimethicone 3 Part, 12 parts of white oil, 0.2 part of Marjoram essential oil, 0.3 part of tea tree ethereal oil, 0.3 part of lemon, 5 parts of vitamin C derivatives, anti-corrosion 0.6 part of agent, 10 parts of moisturizer, 50 parts of deionized water.
Wherein, the preservative is imidazolidinyl urea, and the moisturizer is glycerine.
Embodiment 3:
A kind of whitening cosmetics, by weight, which includes:6 parts of collagen protein powder, dimension life 4 parts of plain E, 8 parts of azelaic acid derivant, 1.0 parts of curcumin, 4 parts of dipotassium glycyrrhizinate, 8 parts of hexadeca-octadecyl alcohol, dimethicone 4 Part, 14 parts of white oil, 0.4 part of Marjoram essential oil, 0.4 part of tea tree ethereal oil, 0.4 part of lemon, 8 parts of vitamin C derivatives, azone 0.5 part, 0.3 part of titanium dioxide, 0.8 part of preservative, 15 parts of moisturizer, 50 parts of deionized water.
Wherein, the preservative is ethylparaben and imidazolidinyl urea, and the moisturizer is hyaluronic acid and glycerine.
Embodiment 4:
A kind of whitening cosmetics, by weight, which includes:8 parts of collagen protein powder, dimension life 5 parts of plain E, 10 parts of azelaic acid derivant, 1.5 parts of curcumin, 5 parts of dipotassium glycyrrhizinate, 10 parts of hexadeca-octadecyl alcohol, dimethicone 5 parts, 15 parts of white oil, 0.5 part of Marjoram essential oil, 0.5 part of tea tree ethereal oil, 0.3 part of lemon, 10 parts of vitamin C derivatives, nitrogen 1.0 parts of ketone, 0.4 part of titanium dioxide, 1 part of preservative, 20 parts of moisturizer, 60 parts of deionized water.
Wherein, the preservative is ethylparaben and imidazolidinyl urea, and the moisturizer is hyaluronic acid and glycerine.
Embodiment 5:
A kind of whitening cosmetics, by weight, which includes:8 parts of collagen protein powder, dimension life E5 parts plain, 10 parts of azelaic acid derivant, 1.5 parts of curcumin, 5 parts of dipotassium glycyrrhizinate, 10 parts of hexadeca-octadecyl alcohol, dimethicone 5 Part, 15 parts of white oil, 0.5 part of Marjoram essential oil, 0.3 part of tea tree ethereal oil, 0.5 part of lemon, 1.5 parts of azone, 1 part of preservative, 20 parts of moisturizer, 0.1 part of antioxidant, 60 parts of deionized water.
Wherein, the preservative is ethylparaben and imidazolidinyl urea, and the moisturizer is hyaluronic acid and glycerine.
Embodiment 6:
A kind of whitening cosmetics, by weight, which includes:8 parts of collagen protein powder, dimension life E5 parts plain, 10 parts of azelaic acid derivant, 1.5 parts of curcumin, 5 parts of dipotassium glycyrrhizinate, 10 parts of hexadeca-octadecyl alcohol, dimethicone 5 Part, 15 parts of white oil, 0.5 part of Marjoram essential oil, 0.3 part of tea tree ethereal oil, 0.5 part of lemon, 1 part of preservative, 20 parts of moisturizer, 0.5 part of antioxidant, 60 parts of deionized water.
Wherein, the preservative is ethylparaben and imidazolidinyl urea, and the moisturizer is hyaluronic acid, glycerine and gathers Ethylene glycol.
Comparative example 1:
A kind of whitening cosmetics, by weight, which includes:6 parts of collagen protein powder, dimension life 4 parts of plain E, 8 parts of azelaic acid derivant, 4 parts of dipotassium glycyrrhizinate, 8 parts of hexadeca-octadecyl alcohol, 4 parts of dimethicone, 14 parts of white oil, 0.4 part of Marjoram essential oil, 0.4 part of tea tree ethereal oil, 0.4 part of lemon, 8 parts of vitamin C derivatives, 0.5 part of azone, titanium dioxide 0.3 part of titanium, 0.8 part of preservative, 15 parts of moisturizer, 50 parts of deionized water.
Wherein, the preservative is ethylparaben and imidazolidinyl urea, and the moisturizer is hyaluronic acid and glycerine.
Comparative example 2:
A kind of whitening cosmetics, by weight, which includes:6 parts of collagen protein powder, dimension life 4 parts of plain E, 1.0 parts of curcumin, 4 parts of dipotassium glycyrrhizinate, 8 parts of hexadeca-octadecyl alcohol, 4 parts of dimethicone, 14 parts of white oil, Ma Qiao 0.4 part of lotus essential oil, 0.4 part of tea tree ethereal oil, 0.4 part of lemon, 8 parts of vitamin C derivatives, 0.5 part of azone, titanium dioxide 0.3 part, 0.8 part of preservative, 15 parts of moisturizer, 50 parts of deionized water.
Wherein, the preservative is ethylparaben and imidazolidinyl urea, and the moisturizer is hyaluronic acid and glycerine.
In order to verify the various performances of whitening cosmetics of the present invention, in above-mentioned 6 embodiments and 2 comparative examples The performances of whitening cosmetics tested.It is specific as follows:
(1) whitening spot-removing measure of merit
The whitening spot-removing effect of whitening cosmetics prepared by embodiment 1-6 and comparative example 1-2 is tested.Tool Body examination method for testing:Each test group chooses 10 volunteers, age 35-55 Sui, there is that skin is obscure, color spot phenomenon;It uses Method:After face cleaning, takes in right amount in the centre of the palm, skin of face is massaged after rubbing heat with the hands, 1 time every night, continuous 12 weeks on probation, photo archive.It comments Valence method:Compare the 0th day and the 12nd week photo and the use feeling for inquiring volunteer, wherein facial skin become it is pale, glossy, It is effective that color spot, which significantly reduces,;Facial skin is obscure to be improved, color spot mitigation is effective;What facial skin did not improve It is invalid.Specific test result is as follows table 1.Trier is paid a return visit after 12 weeks on probation, does not occur showing for skin allergy As showing that the whitening cosmetics are safe and non-toxic.
1 whitening spot-removing measure of merit table of table
According to table 1 it is found that whitening cosmetics prepared by the embodiment of the present invention 1 to embodiment 6 have preferable whitening Freckle effect.Embodiment 3 is compared with comparative example 1, comparative example 2 it is found that in the whitening cosmetics of the present invention, and azelaic acid derives Object and curcumin have synergistic effect to the whitening spot-removing effect for improving whitening cosmetics.
(2) anti-microbial property test
According to QB/T 2738-2012《The evaluation method of daily chemical products antibacterial bacteriostatic effect》, to embodiment 1 to embodiment 6 And the whitening cosmetics (0.2% aqueous solution) of comparison 1, comparative example 2 carry out fungistatic effect test, as a result as shown in table 2 below.
2 fungistatic effect of table tests table
According to QB/T 2738-2012《The evaluation method of daily chemical products antibacterial bacteriostatic effect》Regulation, product bacteriostasis rate >= 50% -90% is to have bacteriostasis, and product bacteriostasis rate >=90% is to have stronger bacteriostasis.As shown in Table 2, embodiment 1, 2,3,4,5,6 all have stronger fungistatic effect.Since embodiment 1 to embodiment 6 is added to azelaic acid derivant and turmeric Element, and azelaic acid derivant is not added in comparative example 1, comparative example 2 is not added with curcumin, it follows that adding azelaic acid simultaneously Derivative and curcumin are conducive to the antibacterial effect for improving the whitening cosmetics, therefore, azelaic acid derivant and curcumin Antibacterial effect to improving whitening cosmetics has synergistic effect.
(3) stability test
Test method:The whitening cosmetics obtained by above-described embodiment 1-6 and comparative example 1-2 are placed in room temperature respectively Under the conditions of place 3 months, seen whether the abnormal conditions such as precipitation, discoloration, spoiled.Test result is shown in Table 3.
3 stability test table of table
Test group 1 month 2 months 3 months
Embodiment 1 Normally Normally Normally
Embodiment 2 Normally Normally Normally
Embodiment 3 Normally Normally Normally
Embodiment 4 Normally Normally Normally
Embodiment 5 Normally Normally Normally
Embodiment 6 Normally Normally Normally
Comparative example 1 Normally It is abnormal It is abnormal
Comparative example 2 Normally It is abnormal It is abnormal
According to table 3 it is found that the whitening cosmetics stability that is prepared to embodiment 6 of the embodiment of the present invention 1 is preferable.
The foregoing is merely the preferred embodiment of the present invention, are not intended to limit the scope of the invention, every at this Under the inventive concept of invention, using equivalent structure transformation made by present specification, or directly/it is used in other indirectly Relevant technical field is included in the scope of patent protection of the present invention.

Claims (8)

1. a kind of whitening cosmetics, which is characterized in that by weight, which includes:Collagen 3~8 parts of powder, 3~5 parts of vitamin E, 5~10 parts of azelaic acid derivant, 0.5~1.5 part of curcumin, dipotassium glycyrrhizinate 3~5 Part, 3~10 parts of hexadeca-octadecyl alcohol, 2~5 parts of dimethicone, 10~15 parts of white oil, 0.1~0.5 part of Marjoram essential oil, tea tree 0.1~0.5 part of essential oil, 0.1~0.5 part of lemon, 0.5~1 part of preservative, 5~20 parts of moisturizer, deionized water 50-60 Part.
2. whitening cosmetics as described in claim 1, which is characterized in that by weight, the whitening spot-removing makeup Product include:It is 5~6 parts of collagen protein powder, 3~4 parts of vitamin E, 6~8 parts of azelaic acid derivant, 1.0~1.5 parts of curcumin, sweet 4~5 parts of oxalic acid dipotassium, 5~8 parts of hexadeca-octadecyl alcohol, 2~4 parts of dimethicone, 10~15 parts of white oil, Marjoram essential oil 0.4 ~0.5 part, 0.3~0.4 part of tea tree ethereal oil, 0.3~0.4 part of lemon, 0.6~0.8 part of preservative, moisturizer 10~15 Part, 50-60 parts of deionized water.
3. the whitening cosmetics stated such as claim 1, which is characterized in that the whitening cosmetics further include parts by weight The vitamin C derivatives that number is 5~10 parts.
4. the whitening cosmetics stated such as claim 1, which is characterized in that the whitening cosmetics further include parts by weight The azone that number is 0.5~1.5 part.
5. the whitening cosmetics stated such as claim 1, which is characterized in that the whitening cosmetics further include parts by weight The titanium dioxide that number is 0.3~0.4 part.
6. the whitening cosmetics stated such as claim 1, which is characterized in that the whitening cosmetics further include parts by weight The antioxidant that number is 0.1~0.5 part.
7. the whitening cosmetics stated such as claim 1, which is characterized in that the preservative include ethylparaben and/or Imidazolidinyl urea.
8. the whitening cosmetics stated such as claim 1, which is characterized in that the moisturizer includes hyaluronic acid, glycerine, third One or more compositions in triol, butanediol, polyethylene glycol, xylitol, polypropylene glycol, D-sorbite.
CN201810234521.1A 2018-03-20 2018-03-20 Whitening cosmetics Withdrawn CN108309818A (en)

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CN201810234521.1A CN108309818A (en) 2018-03-20 2018-03-20 Whitening cosmetics

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Application Number Priority Date Filing Date Title
CN201810234521.1A CN108309818A (en) 2018-03-20 2018-03-20 Whitening cosmetics

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Publication Number Publication Date
CN108309818A true CN108309818A (en) 2018-07-24

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CN201810234521.1A Withdrawn CN108309818A (en) 2018-03-20 2018-03-20 Whitening cosmetics

Country Status (1)

Country Link
CN (1) CN108309818A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113101233A (en) * 2021-04-29 2021-07-13 山东理工大学 Hand cream rich in tetrahydrocurcumin nano-selenium and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113101233A (en) * 2021-04-29 2021-07-13 山东理工大学 Hand cream rich in tetrahydrocurcumin nano-selenium and preparation method thereof

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