CN112754978A - Moisturizing, relieving and repairing composition - Google Patents

Moisturizing, relieving and repairing composition Download PDF

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Publication number
CN112754978A
CN112754978A CN202110148149.4A CN202110148149A CN112754978A CN 112754978 A CN112754978 A CN 112754978A CN 202110148149 A CN202110148149 A CN 202110148149A CN 112754978 A CN112754978 A CN 112754978A
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Prior art keywords
ceramide
composition
extract
skin
weight
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CN202110148149.4A
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Chinese (zh)
Inventor
姚哲男
舒鹏
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Shenzhen Hujia Technology Co ltd
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Shenzhen Hujia Technology Co ltd
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Priority to CN202110148149.4A priority Critical patent/CN112754978A/en
Publication of CN112754978A publication Critical patent/CN112754978A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706Algae
    • A61K8/9711Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

Abstract

The invention relates to the technical field of cosmetics, in particular to a moisturizing, relieving and repairing composition. A moisturizing soothing repair composition comprising water, a skin conditioner, a humectant, a pH adjuster, a thickener, and a solubilizer; wherein the skin conditioning agent comprises ceramide, plant extract and fermentation product of yeast schizosaccharomyces, wherein the ceramide is selected from at least one of vegetative ceramide, biological ceramide and ceramide-like.

Description

Moisturizing, relieving and repairing composition
Technical Field
The invention relates to the technical field of cosmetics, in particular to a moisturizing, relieving and repairing composition.
Background
Healthy, soft skin is a constant pursuit for everyone, especially women. Healthy, moist skin is closely related to the amount of moisture it contains. The related research in 1952 indicates that the skin dryness is directly related to the water shortage of the stratum corneum, and when the hydration rate of the stratum corneum is lower than 10%, the skin is easily dry and rough in appearance, and a series of symptoms such as desquamation, pruritus and inflammation are easily caused. Therefore, early studies were to attribute the occurrence of dry skin symptoms primarily to the loss of stratum corneum water. With the progress of the related research on skin moisturizing, it is more discovered that skin dryness is not simply water deficiency, but rather skin barrier dysfunction destabilizes the hydration state thereof, leading to the associated disturbance of skin physiological processes, and the accumulation of aged keratinocytes on the surface layer. After the skin is dry, the light is scattered on the surface of the skin due to the roughness and unsmooth of the surface skin, and the reddish skin blood microcirculation is blocked by the thick keratinized cells, so the skin becomes dull and pale in appearance. In addition, dry skin appears more sensitive and irritated due to the mild dehydration of the skin surface. The physical properties of dry skin are also changed, and itching occurs after the skin is sensed by nerve endings in the dermis layer of the skin, which causes a series of skin problems.
In recent years, with the pace of modern life and the increasing working pressure, people are suffering from dry skin due to overtime, frequent use of daily chemicals, interference of physical factors and environmental factors, and the incidence and severity of the dry skin are increasing. The reduction in skin moisture retention results in a reduction in skin barrier function which further reduces the moisture retention of the skin, creating a vicious circle which reduces skin tolerance and makes healthy skin susceptible to premature aging flaccidity. In addition, the poor basic care of skin moisture retention also affects the absorption of nutrients by the skin and the health of the skin.
Most of the existing skin care products adopt chemical preparations, hormones and the like, chemical preservatives are usually added, certain influence is caused on the skin, the phenomenon of skin allergy is easily caused, the skin care effect of 'instant effect' is generated after the skin care products containing the hormones and harmful preparations are used, but the skin care products cause great damage to the skin health of consumers, and the phenomena of telangiectasia erythema, pimple, facial skin atrophy, acne rosacea, pigmentation and the like are generated on the skin after the skin care products are used for a long time, so that the normal ecological balance of the skin is damaged.
Disclosure of Invention
Unless otherwise indicated, implied from the context, or customary in the art, all parts and percentages herein are by weight and the testing and characterization methods used are synchronized with the filing date of the present application. To the extent that a definition of a particular term disclosed in the prior art is inconsistent with any definitions provided herein, the definition of the term provided herein controls.
The technical features of the technical solutions provided by the present invention are further clearly and completely described below with reference to the specific embodiments, and the scope of protection is not limited thereto.
The words "preferred", "preferably", "more preferred", and the like, in the present invention, refer to embodiments of the invention that may provide certain benefits, under certain circumstances. However, other embodiments may be preferred, under the same or other circumstances. Furthermore, the recitation of one or more preferred embodiments does not imply that other embodiments are not useful, nor is it intended to exclude other embodiments from the scope of the invention. The sources of components not mentioned in the present invention are all commercially available.
The inventor of the invention has conducted earnest research to solve the problems and then discovered that a moisturizing, relieving and repairing composition is provided, a specific compounded skin conditioner is high in safety, does not contain chemical preservatives and is harmless to human skin health, and by controlling the proportion of ceramide, plant extracts and yeast dehiscence fermentation products in the skin conditioner, raw materials are matched with one another and used in a synergistic effect, and the hamamelis virginiana extract, horse chestnut seed extract, bilberry fruit extract, ditch antler vegetable extract, palm leaf tree extract, radix ophiopogonis extract, radix sophorae flavescentis extract and twisted cactus stem extract are used as main plant extract components, so that skin repairing, moisturizing and water locking are performed on the basis of relieving and anti-allergy, and the composition has good soothing, anti-allergy, repairing, moisturizing and mildness.
In a first aspect of the invention, there is provided a moisturizing soothing repair composition comprising water, a skin conditioner, a humectant, a pH adjuster, a thickener, and a solubilizer; wherein the skin conditioning agent comprises ceramide, plant extract and fermentation product of yeast schizosaccharomyces, wherein the ceramide is selected from at least one of vegetative ceramide, biological ceramide and ceramide-like.
The composition preferably comprises 0.8-10% of skin conditioner, 10-30% of humectant, 0.01-0.15% of pH regulator, 0.1-2% of thickener, 1-5% of solubilizer and the balance of water by weight percentage.
Examples of the plant ceramide include compounds extracted from rice bran, rice, corn, konjac, maitake, pleurotus citrinopileatus (pleurotus cornucopiae), soybean, beet, wheat, and the like, and have a structure in which ceramide is bonded to sugar. Preferred among these vegetative ceramides are glycosphingolipids, particularly preferred are cerebrosides, and most preferred is glucosylceramide.
Examples of the biological ceramide include ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6II, ceramide 7, ceramide 8, ceramide 9, and ceramide 10. In the present invention, among them, at least one selected from among ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6II, and ceramide 7 is preferable, ceramide 1, ceramide 2, ceramide 3, ceramide 4, and ceramide 6II are more preferable, and a mixture of ceramide 1, ceramide 3, and ceramide 6II is further preferable, and usually, ceramide 1, ceramide 3, and ceramide 6II need to be selected from (1 to 3): 1: (1-3) in the dosage range; preferably, the ratio of (1.5-2.5): 1: (1-2), preferably the total mass of the mixture of ceramide 1, ceramide 3 and ceramide 6II is added in an amount of 0.5-3 wt%, more preferably 1-2 wt%, based on the total mass of the composition.
In view of the solubility of ceramide in the system, it is more effective to use ceramide within the above-mentioned preferred content range, and in the case of using ceramide within the further preferred content range, ceramide is encapsulated by the specific three-dimensional structure of natural phospholipid and enzyme present in the plant extract in cooperation with the plant extract, thereby forming a protective, nourishing hydration layer.
Examples of the ceramides include N-lauroyl-L-glutamic acid bis (phytosterol/2-octyldodecyl) ester, a copolymer of glycerylamide ethyl methacrylate/stearyl methacrylate, a polyquaternium 51, and N- (tetradecyloxyhydroxypropyl) -N-hydroxydecanoamide.
The plant extract is preferably at least one selected from Hamamelis virginiana extract, Aesculus hippocastanum seed extract, Vaccinium myrtillus fruit extract, Pelvetia siliquosa extract, palm leaf tree extract, radix Ophiopogonis extract, radix Sophorae Flavescentis extract, and Opuntia Dillenii stem extract.
The Hamamelis virginiana extract contains various tannins such as Ellagitannin and Hamamelitiannin, and has sebum secretion regulating, moisturizing and whitening effects. Has tranquilizing and soothing effects, and can be used for treating chap, sunburn and acne. Can effectively help the skin to regenerate at night. It has excellent effects of removing under-eye puffiness, relaxing and relieving oily skin or allergic skin.
The horse chestnut seed extract is preferably European horse chestnut seed extract, is rich in saponins compounds, has effects of removing oil and fat, is mild and bioactive, has good penetration ability, has anti-dermatitis effect, can relieve skin allergy by combining with strong eliminating effect on superoxide radical, and can prevent and treat skin erythema, edema, inflammation and allergy etc.
The cowberry fruit extract is rich in anthocyanin, has inhibition effect on elastase and collagenase activities, can slow down the explanation of elastin and collagen, can maintain the elasticity of skin, and can be used as cosmetic anti-wrinkle and anti-aging agent in combination with the antioxidant property; meanwhile, the whitening cream can inhibit the activity of melanocytes and has certain whitening effect; can inhibit free histamine, and is therefore an anti-allergy inhibitor; also has anti-inflammatory effect, and can be used as anti-inflammatory agent.
The extract of Pelvetia siliquosa is derived from Sargassum plant, and is a plant hormone precursor, and has effects of resisting aging, increasing cell division and proliferation, increasing intercellular substance (such as collagen and protein polysaccharide), inhibiting MMP-3 generation, capturing free radical, and protecting cell.
The palm leaf tree extract mainly contains emodin and chrysophanol. Can promote skin blood circulation, improve skin permeability, promote absorption of effective components, inhibit bacteria, remove acne, and astringe skin, and is a good cosmetic raw material.
The radix ophiopogonis extract is derived from radix ophiopogonis, is rich in active ingredients of polyfructose, has strong drought resistance, and prevents excessive loss of skin moisture by strengthening adhesion of the upper layer of epidermis and recombining the barrier function of skin. Reduce the disintegration of the cuticle and achieve the moisturizing effect.
The radix Sophorae Flavescentis extract contains various alkaloids. Has different inhibitory effects on various organisms and fungi, and has antibacterial and anti-inflammatory effects; cultured in fibroblasts and the like, can effectively promote the generation of collagen, and has the anti-aging effect; has good moisture-keeping and water-holding effects and has water replenishing function.
The prickly pear stem extract contains various effective components such as polysaccharide substances, triterpenoid and the like, has the effects of promoting the proliferation of epidermal growth factors, clearing free radicals, effectively delaying skin aging and improving the resistance of the body to external stimulation; the Opuntia Dillenii stem extract contains various amino acids required by human body, and can directly supplement nutrition for skin and help to maintain skin balance.
In the composition, the plant extract is preferably a mixture of a hamamelis virginiana extract, a aesculus hippocastanum seed extract, a vaccinum myrtillus fruit extract, a carrageen sulcifera extract and a palmleaf tree extract, and the mass ratio of the hamamelis virginiana extract, the aesculus hippocastanum seed extract, the vaccinum myrtillus fruit extract, the carrageen sulcus extract and the palmleaf tree extract is (0.5-2): (0.1-1): (0.1-1): (0.1-1): (0.1-0.5): (0.1-0.5): (0.1-0.5): (0.1-0.5). In the composition, the plant extract accounts for 0.5-5% of the total mass of the composition, and 2-4% of the total mass of the composition is preferred.
After the plant extracts are added, the rich amino acids, saccharides, mineral substances and other nutritional ingredients contained in the plant extracts can moisten the skin and establish a healthy skin barrier, the plant extracts are researched and adjusted to be favorable for refreshing the high-temperature stability of the ceramide at a proper proportion, and the phenomena of coagulation, flocculation and agglomeration are avoided.
In the composition, the yeast fermentation product is preferably a yeast fermentation product lysate which is obtained by culturing, inactivating and decomposing bifidobacterium to obtain a metabolite, a cytoplasm fragment, a cell wall component and a polysaccharide complex; has strong immunosuppressive activity, can promote DNA repair, can effectively protect skin from being damaged by ultraviolet rays, is used for skin care, sun protection and after-sun care products of emulsion, water-based and hydroalcoholic systems, and helps to prevent photoaging of epidermis and dermis.
In addition, the schizosaccharomyces cerevisiae fermentation product lysate can generate small molecules which comprise vitamin B group, minerals, amino acids and the like and are beneficial to skin care, and the schizosaccharomyces cerevisiae fermentation product lysate is high-quality yeast essence only used for skin care. It has effects in promoting metabolism of stratum corneum, capturing free radicals, inhibiting lipid peroxidation, whitening skin, and resisting aging. In the composition, the mass percentage of the yeast for bifidus fermentation product in the total composition is preferably 0.01-0.5%, more preferably 0.1-0.5%.
As the humectant of the present invention, polyhydric alcohols, glucitol derivatives, and hyaluronic acid are preferably included.
The polyhydric alcohol in the humectant is preferably a polyhydric alcohol of C2-C30, which may be a polyhydric alcohol having an ether bond in the molecule or a polyhydric alcohol having no ether bond, and preferably a water-soluble saturated aliphatic alcohol of C2-C30 in which the polyhydric alcohol of C2-C30 has 2-6 hydroxyl groups. Examples of such polyols include: diols such as ethylene glycol, diethylene glycol, triethylene glycol, tetraethylene glycol, polyethylene glycol, propylene glycol, 1, 3-propanediol, dipropylene glycol, polypropylene glycol, 1, 3-butanediol, 1, 2-butanediol, 1, 4-butanediol, 2, 3-butanediol, 1, 2-pentanediol, and the like; trihydric alcohols such as glycerin, trimethylolpropane, etc.; tetrahydric alcohols such as diglycerin, erythritol, pentaerythritol, and the like; pentahydric alcohols such as xylitol, triglycerin, and the like; hexahydric alcohols such as sorbitol, mannitol, and the like; and their polymers such as diglycerin, triglycerol, tetraglycerol, polyglycerin, and the like; as such polyhydric alcohols, butanediol, 1, 3-propanediol, 1, 2-pentanediol, 1, 2-hexanediol, glycerol, diglycerol, triglycerol, betaine are more preferable. The above-mentioned preferred polyhydric alcohols may be used alone or in combination of two or more; for better stability, a mixture of butanediol, 1, 2-hexanediol and 1, 2-pentanediol is preferably used as the most suitable polyol, and butanediol, 1, 2-hexanediol and 1, 2-pentanediol are more preferably (5 to 9): (3-6): (1-3), and the stability in the preparation process can be improved by mixing 1, 3-propanediol, 1, 2-pentanediol, butanediol and methyl glucitol polyether.
The glucitol derivative is preferably methyl glucitol polyether, which is a nonionic surfactant obtained by reacting methyl glucose with ethylene oxide, and generally includes methyl glucitol polyether-10 and methyl glucitol polyether-20, especially methyl glucitol polyether-10, which can improve the overall performance of the composition and can help the skin conditioning agent to rapidly penetrate into the skin.
The hyaluronic acid is preferably 4D sodium hyaluronate, wherein 4D sodium hyaluronate is commercially available, and the INCI includes sodium hyaluronate crosspolymer, sodium hyaluronate, acetylated sodium hyaluronate, hydrolyzed sodium hyaluronate, 1, 2-pentanediol, ethylhexylglycerin, and water.
To obtain, the mass ratio of polyol, glucitol derivative, and hyaluronic acid is preferably 1: (0.3-2): (0.1-2).
Any commonly used pH adjuster in general cosmetics can be used as the pH adjuster. Examples of the acidic pH adjuster include hydroxy acids such as lactic acid and glycolic acid; dicarboxylic acids such as malic acid, tartaric acid, malonic acid, succinic acid, and adipic acid; tricarboxylic acids such as citric acid; acidic amino acids such as glutamic acid and aspartic acid; hydrochloric acid, phosphoric acid, and like inorganic acids. Examples of the alkaline pH adjuster include alkali metal bicarbonates such as sodium bicarbonate; aminomethyl propanol; alkali metal carbonates such as sodium carbonate and the like are preferable, and aminomethylpropanol is preferable because it can further improve emulsifiability while adjusting pH.
The thickener is preferably a water-soluble thickener, and examples thereof include carboxyvinyl polymers, sodium polyacrylate, polyethylene glycol, acrylic acid/alkyl methacrylate copolymers, polyoxyethylene polyoxypropylene block copolymers, polyvinyl alcohol, polyvinyl pyrrolidone, polyvinyl methyl ether, methyl cellulose, ethyl cellulose, hydroxyethyl cellulose, hydroxypropyl methyl cellulose, cationized cellulose, sodium alginate, propylene glycol alginate, guar gum, locust bean gum, carrageenan, xanthan gum, dextran, bentonite, and the like, and carboxyvinyl polymers, acrylic acid/alkyl methacrylate copolymers, polyvinyl alcohol, polyvinyl pyrrolidone, and hydroxypropyl methyl cellulose are preferable. These water-soluble thickeners may be used singly or in any combination of two or more. Among them, in the composition of the present invention, a styrene/acrylic ester copolymer is more preferable.
Preferred as the solubilizer are polysorbate 20, PEG-30 hydrogenated castor oil, PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil, PPG-26-Buteth-2, or capryl/capric glucoside, and most preferred among these solubilizers is PEG-40 hydrogenated castor oil.
In addition, the composition of the present invention may contain ingredients generally used in cosmetics or quasi-drugs in amounts and in such ranges that the effects of the present invention are not impaired. Examples thereof include polymer emulsions, other oily components, waxes, hydrocarbon oils, higher fatty acids, higher alcohols, synthetic ester oils, coating agents, and ultraviolet absorbers.
Examples of the natural water-soluble polymer include vegetable polymers (e.g., gum arabic, tragacanth gum, galactan, guar gum, locust bean gum, karaya gum, carrageenan, pectin, agar, quince seed (quince), algae colloid (brown algae extract), starch (rice, corn, potato, wheat), and glycyrrhizic acid); microbial polymers (e.g., xanthan gum, dextran, succinoglucan, pullulan, etc.); animal polymers (e.g., collagen, casein, albumin, gelatin, etc.), and the like.
Examples of the semisynthetic water-soluble polymer include starch-based polymers (e.g., carboxymethyl starch, methyl hydroxypropyl starch, etc.); cellulose polymers (methyl cellulose, ethyl cellulose, methylhydroxypropyl cellulose, hydroxyethyl cellulose, sodium cellulose sulfate, hydroxypropyl cellulose, carboxymethyl cellulose, sodium carboxymethyl cellulose, crystalline cellulose, cellulose powder, etc.); alginic acid polymers (e.g., sodium alginate, propylene glycol alginate, etc.), and the like.
Examples of the water-soluble polymer to be synthesized include vinyl polymers (e.g., polyvinyl alcohol, polyvinyl methyl ether, polyvinyl pyrrolidone, carboxyvinyl polymer, etc.); polyoxyethylene polymers (e.g., polyoxyethylene polyoxypropylene copolymers of polyethylene glycol 20,000, 40,000, 60,0000, etc.); acrylic polymers (for example, sodium polyacrylate, polyethylacrylate, polyacrylamide, etc.); a polyethyleneimine; cationic polymers, and the like.
Examples of the oily component include liquid oils and fats, solid oils and fats, waxes, hydrocarbons, higher fatty acids, higher alcohols, and synthetic ester oils.
Examples of the liquid oils and fats include avocado oil, camellia oil, turtle oil, macadamia nut oil, corn oil, mink oil, olive oil, rapeseed oil, egg yolk oil, sesame oil, almond oil, wheat germ oil, camellia oil, castor oil, linseed oil, safflower oil, cottonseed oil, perilla oil, soybean oil, peanut oil, tea seed oil, torreya oil, rice bran oil, paulownia oil, japanese tung oil, jojoba oil, germ oil, triglycerin, and the like.
Examples of the solid fat and oil include cacao butter, coconut oil, horse fat, hydrogenated coconut oil, palm oil, beef tallow, mutton tallow, hydrogenated beef tallow, palm kernel oil, lard, beef bone fat, beeswax kernel oil, hydrogenated oil, beef foot fat, beeswax, hydrogenated castor oil, and the like.
Examples of the waxes include beeswax, candelilla wax, cotton wax, carnauba wax, bayberry wax, white wax, spermaceti wax, montan wax, rice bran wax, lanolin, kapok wax, lanolin acetate, liquid lanolin, sugar cane wax, lanolin fatty acid isopropyl ester, hexyl laurate, reduced lanolin, jojoba wax, hard lanolin, shellac wax, POE lanolin alcohol ether, POE lanolin alcohol acetate, POE cholesterol ether, lanolin fatty acid polyglycol ester, and POE hydrogenated lanolin alcohol ether.
Examples of the hydrocarbon oil include liquid paraffin, ceresin, squalane, pristane, paraffin, ceresin, squalene, vaseline, and microcrystalline wax.
Examples of the higher fatty acid include lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, undecylenic acid, tall oil acid, isostearic acid, linoleic acid, linolenic acid, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
As the higher alcohol, for example, a straight-chain alcohol (e.g., lauryl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, myristyl alcohol, oleyl alcohol, cetearyl alcohol, etc.); branched alcohols (e.g., monostearyl glyceryl ether (batyl alcohol), 2-decyltetradecanol, lanolin alcohol, cholesterol, phytosterol, hexyldodecanol, isostearyl alcohol, octyldodecanol, etc.), etc.
Examples of the synthetic ester oil include isopropyl myristate, cetyl octanoate, octyldodecyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, decyl oleate, hexyldecyl dimethyloctanoate, cetyl lactate, myristyl lactate, lanolin acetate, isocetyl stearate, isocetyl isostearate, cholesterol 12-hydroxystearate, ethylene glycol di (2-ethylhexanoate), dipentaerythritol fatty acid ester, N-alkylene glycol monoisostearate, neopentyl glycol didecanoate, diisostearyl malate, glycerol di (2-heptylundecanoate), trimethylolpropane tri (2-ethylhexanoate), trimethylolpropane triisostearate, pentaerythritol tetra (2-ethylhexanoate), Glyceryl tris (2-ethylhexanoate), glyceryl trioctanoate, glyceryl triisopalmitate, trimethylolpropane triisostearate, cetyl 2-ethylhexanoate, 2-ethylhexyl palmitate, glyceryl trimyristate, glyceryl tris (2-heptylundecanoate), methyl ricinoleate, oleyl oleate, acetyl glycerol, 2-heptylundecyl palmitate, diisobutyl adipate, N-lauroyl-L-glutamic acid-2-octyldodecyl ester, di (2-heptylundecyl) adipate, ethyl laurate, di (2-ethylhexyl) sebacate, 2-hexyldecyl myristate, 2-hexyldecyl palmitate, 2-hexyldecyl adipate, diisopropyl sebacate, isopropyl oleate, isopropyl myristate, isopropyl palmitate, 2-ethylhexyl succinate, triethyl citrate, and the like.
Examples of the coating agent include anionic coating agents (e.g., (meth) acrylic acid/(meth) acrylate copolymers, methyl vinyl ether/maleic anhydride polymers, etc.), cationic coating agents (e.g., cationized cellulose, dimethyldiallylammonium chloride polymers, dimethyldiallylammonium chloride/acrylamide copolymers, etc.), and nonionic coating agents (e.g., polyvinyl alcohol, polyvinyl pyrrolidone, polyvinyl acetate, polyacrylate copolymers, (meth) acrylamide, high molecular silicone, silicone resins, trimethylsiloxysilicates, etc.).
Examples of the ultraviolet absorber include benzoic acid-based ultraviolet absorbers (e.g., p-aminobenzoic acid (hereinafter abbreviated as "PABA"), PABA monoglyceride, N-dipropoxypPABA ethyl ester, N-diethoxypPABA ethyl ester, N-dimethylpPABA butyl ester, N-dimethylpPABA ethyl ester, etc.); anthranilic acid-based ultraviolet absorbers (e.g., homoyl-N-acetyl anthranilate); salicylic acid-based ultraviolet absorbers (e.g., amyl salicylate, salicylic acid ester, high salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, p-isopropyl alcohol phenyl salicylate, etc.); cinnamic acid-based ultraviolet absorbers (e.g., octyl methoxycinnamate, ethyl 4-isopropylcinnamate, methyl 2, 5-diisopropylcinnamate, ethyl 2, 4-diisopropylcinnamate, methyl 2, 4-diisopropylcinnamate, propyl p-methoxycinnamate, isopropyl p-methoxycinnamate, isoamyl p-methoxycinnamate, octyl p-methoxycinnamate (2-ethylhexyl p-methoxycinnamate), 2-ethoxyethyl p-methoxycinnamate, cyclohexyl p-methoxycinnamate, ethyl α -cyano- β -phenylcinnamate, 2-ethylhexyl α -cyano- β -phenylcinnamate, glycerol mono-2-ethylhexanoyl-di-p-methoxycinnamate, etc.); benzophenone-based ultraviolet absorbers (e.g., 2, 4-dihydroxybenzophenone, 2' -dihydroxy-4-methoxybenzophenone, 2' -dihydroxy-4, 4' -dimethoxybenzophenone, 2',4,4' -tetrahydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4 ' -methylbenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonate, 4-phenylbenzophenone, 2-ethylhexyl-4 ' -phenyl-benzophenone-2-carboxylate, 2-hydroxy-4-n-octyloxybenzophenone, 4-hydroxy-3-carboxybenzophenone, etc.); 3- (4' -methylbenzylidene) -d, l-camphor, 3-benzylidene-d, l-camphor; 2-phenyl-5-methylbenzoxazole; 2,2' -hydroxy-5-methylphenylbenzotriazole; 2- (2 '-hydroxy-5' -tert-octylphenyl) benzotriazole; 2- (2' -hydroxy-5 ' -methylphenylbenzotriazole, dibenzylhydrazine (ジベンザラジン), dianisiloylmethane, 4-methoxy-4 ' -tert-butyldibenzoylmethane, 5- (3, 3-dimethyl-2-norbornyl) -3-pentan-2-one, dimorpholinopyridazine, 2-ethylhexyl-2-cyano-3, 3-diphenylacrylate, 2, 4-bis- { [4- (2-ethylhexyloxy) -2-hydroxy ] -phenyl } -6- (4-methoxyphenyl) - (1,3,5) -triazine and the like.
Detailed Description
The present invention is described in detail below with reference to examples, which are provided for the purpose of further illustration only and are not to be construed as limiting the scope of the present invention, and the insubstantial modifications and adaptations thereof by those skilled in the art based on the teachings of the present invention will still fall within the scope of the present invention.
Example 1
A moisturizing and soothing repairing composition is shown in Table 1, and comprises the following components of a clean container, pure water is added, the pure water is heated to 45 ℃, a humectant, a thickening agent and a pH regulator are added, the materials are uniformly mixed through stirring, the temperature is continuously reduced to 40 ℃, a solubilizer and a skin conditioner are added, the mixture is stirred, and the mixture is discharged after the materials are qualified through material taking and detection.
TABLE 1
Figure BDA0002931029960000101
Example 2
According to the formula shown in the table 2, a clean container is taken, pure water is added, the temperature is increased to 45 ℃, the humectant, the thickening agent and the pH regulator are added, the materials are uniformly mixed by stirring, the temperature is continuously reduced to 40 ℃, the solubilizer and the skin conditioner are added, the materials are stirred, and the materials are discharged after the materials are qualified through detection.
TABLE 2
Figure BDA0002931029960000111
Example 3
According to the formula shown in the table 3, a clean container is taken, pure water is added, the temperature is increased to 45 ℃, the humectant, the thickening agent and the pH regulator are added, the materials are uniformly mixed by stirring, the temperature is continuously reduced to 40 ℃, the solubilizer and the skin conditioner are added, the materials are stirred, and the materials are discharged after the materials are qualified through detection.
TABLE 3
Figure BDA0002931029960000112
Figure BDA0002931029960000121
Example 4
According to the formula shown in the table 4, a clean container is taken, pure water is added, the temperature is increased to 45 ℃, the humectant, the thickening agent and the pH regulator are added, the materials are uniformly mixed by stirring, the temperature is continuously reduced to 40 ℃, the solubilizer and the skin conditioner are added, the materials are stirred, and the materials are discharged after the materials are qualified through detection.
TABLE 4
Figure BDA0002931029960000122
Figure BDA0002931029960000131
Example 5
According to the formula shown in Table 5, a clean container is taken, pure water is added, the temperature is increased to 45 ℃, the humectant, the thickener and the pH regulator are added, the materials are uniformly mixed by stirring, the temperature is continuously reduced to 40 ℃, the solubilizer and the skin conditioner are added, the materials are stirred, and the materials are discharged after the materials are qualified through detection.
TABLE 5
Figure BDA0002931029960000132
Example 6
According to the formula shown in table 6, a clean container is taken, pure water is added, the temperature is increased to 45 ℃, the humectant, the thickener and the pH regulator are added, the materials are uniformly mixed by stirring, the temperature is continuously reduced to 40 ℃, the solubilizer and the skin conditioner are added, the materials are stirred, and the materials are discharged after the materials are qualified through detection.
TABLE 6
Figure BDA0002931029960000141
Example 7
According to the formula shown in Table 7, a clean container is taken, pure water is added, the mixture is heated to 45 ℃, the humectant, the thickening agent and the pH regulator are added, the materials are uniformly mixed by stirring, the temperature is continuously reduced to 40 ℃, the solubilizer and the skin conditioner are added, the mixture is stirred, and the materials are discharged after the materials are qualified through detection.
TABLE 7
Figure BDA0002931029960000151
Evaluation of Performance
1. Evaluation of stability at ordinary temperature: the compositions of the examples obtained were each left to stand at room temperature 25 ℃ for 24h to observe whether the composition had changed, and if there was delamination or coagulum X, there was slight delamination or coagulum Delta, and no change was O.
2. Evaluation of high temperature stability: the compositions of the examples obtained were each left at 45 ℃ for 1 month to observe whether the composition had changed, and if there was any delamination or coagulation, it was slightly delaminated or coagulated by X, and no change was O.
3. Usability: 28 men and women were selected, and a total of 56 persons were individually prepared by applying 1ml of each sample from each example to the arm, and rating the sticky feeling and the absorption feeling of the composition (5 is very good, 4 is good, 3 is general, 2 is not good, 1 is very poor), and an average value was given.
TABLE 8
Components Stability at Normal temperature High temperature stability Sticky feeling Sensation of absorption
Example 1 Ο Ο 4.6 4.5
Example 2 X 3.3 3.1
Example 3 X X 3.4 2.5
Example 4 Ο 3.2 2.8
Example 5 4.1 4.1
Example 6 Ο Ο 3.8 3.2
Example 7 Ο 4.2 4.5

Claims (10)

1. A moisturizing soothing repair composition characterized by comprising water, a skin conditioner, a humectant, a pH adjuster, a thickener, and a solubilizer; wherein the skin conditioning agent comprises ceramide, plant extract and fermentation product of yeast schizosaccharomyces, wherein the ceramide is selected from at least one of vegetative ceramide, biological ceramide and ceramide-like.
2. The composition according to claim 1, wherein the ceramide is 0.1-3% by mass of the total composition.
3. The composition as claimed in claim 2, wherein the plant extract accounts for 0.5-5% of the total weight of the composition.
4. The composition of claim 1, wherein the mass percent of the yeast for bifidus fermentation product in the total composition is 0.01-0.5%.
5. The composition according to any one of claims 1 to 4, wherein the plant extract is at least one selected from the group consisting of Hamamelis virginiana extract, Aesculus hippocastanum seed extract, Vaccinium myrtillus fruit extract, Pelvetia canaliculata extract, Palmaria palmata extract, Ophiopogon japonicus extract, Sophora flavescens extract, and Opuntia ficus-indica stem extract.
6. The composition of claim 5, wherein the humectant comprises a polyhydric alcohol, a glucitol derivative, and hyaluronic acid.
7. The composition of claim 6, wherein the polyol is a water-soluble C2-C30 saturated aliphatic alcohol having 2-6 hydroxyl groups.
8. The composition of claim 7, wherein the glucitol derivative is methyl glucitol polyether.
9. The composition of claim 8, wherein the polyol, the glucitol derivative, and the hyaluronic acid are present in a mass ratio of 1: (0.1-0.5): (0.1-0.5).
10. The composition according to any one of claims 1 to 9, comprising 0.8 to 10% by weight of a skin conditioning agent, 10 to 30% by weight of a moisturizer, 0.01 to 0.15% by weight of a pH regulator, 0.1 to 2% by weight of a thickener, 1 to 5% by weight of a solubilizer, and the balance of water.
CN202110148149.4A 2021-02-03 2021-02-03 Moisturizing, relieving and repairing composition Pending CN112754978A (en)

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