CN112717059A - 一种抗肿瘤中药组合物及其制备方法 - Google Patents

一种抗肿瘤中药组合物及其制备方法 Download PDF

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CN112717059A
CN112717059A CN202110086755.8A CN202110086755A CN112717059A CN 112717059 A CN112717059 A CN 112717059A CN 202110086755 A CN202110086755 A CN 202110086755A CN 112717059 A CN112717059 A CN 112717059A
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马殿霞
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Abstract

本发明涉及一种抗肿瘤中药组合物及其制备方法，包括以下重量份数的组分：透骨草5‑30克、甘草5‑30克、当归5‑30克、黄芪5‑28克、夏枯草5‑20克、香附子5‑15克、淫羊藿5‑28克、三七3‑20克、草乌3‑30克、生半夏5‑15克、贝母3‑30克、熟地3‑30克、蒲公英5‑30克、白芍5‑30克、舌草3‑28克、半枝莲5‑25克、党参5‑28克等。本发明的有益效果是：针对性强，君臣佐使，科学配伍，用于软坚散结，激发巨噬细胞的活力，提高淋巴细胞转化率，抑制癌瘤细胞的生长、破坏肿瘤周围及癌灶内纤维蛋白凝集，阻止癌细胞着床，防止肿瘤的生长和转移。

Description

一种抗肿瘤中药组合物及其制备方法
技术领域
本发明涉及中医药物技术领域，具体是指一种抗肿瘤中药组合物及其制备方法。
背景技术
随着我国人口老龄化趋势加剧、以及不良生活方式广泛存在，我国癌症发病和死亡率还将不断上升，近十年来每年增加约4％，调整年龄因素之后，每年增长约2％。目前中药治疗肿瘤主要从祛邪、扶正两方面入手，据病人的实际情况标本兼顾、辨证治疗。研究发现具有祛邪作用的中草药多能作用于肿瘤细胞生长过程，通过干扰肿瘤细胞的核酸等遗传物质的合成、有丝分裂周期、繁殖信息传递等生长和转移过程起到抑制肿瘤细胞增殖过程、直接杀伤肿瘤细胞等作用。肿瘤是严重危害人类健康及生命的常见慢性疾病。随着中药治疗肿瘤研究的不断深入，其在增强机体自身对肿瘤细胞的免疫以及促进肿瘤细胞凋亡两方面独特的疗效和较低的毒副作用，越来越引起人们关注。中药抑制体内、外肿瘤细胞生长的实验研究较多，对抗肿瘤药理研究报道很少，当前对中药抗肿瘤疗效机理方面的研究相对落后，思路上较为单一。一些疗效较好的治法其治疗机理研究不够深人，临床用药缺少以药物机理作指导，尤其对于肿瘤手术后、放化疗后和晚期癌症患者，缺乏有效缓解病情的中药药物。
发明内容
以解决上述背景技术中提出的问题，本发明的目的在于提供一种抗肿瘤中药组合物及其制备方法，用于调节脏腑气血功能，恢复人体免疫功能，防止肿瘤的生长和转移。
为解决上述技术问题，本发明提供的技术方案为：一种抗肿瘤中药组合物及其制备方法，包括以下重量份数的组分：透骨草5-30克、甘草5-30克、当归5-30克、黄芪5-28克、夏枯草5-20克、香附子5-15克、淫羊藿5-28克、三七3-20克、草乌3-30克、生半夏5-15克、贝母3-30克、熟地3-30克、蒲公英5-30克、白芍5-30克、舌草3-28克、半枝莲5-25克、党参5-28克等。
进一步的，具体包括以下步骤：(1)将透骨草5-30克、甘草5-30克、当归5-30克、黄芪5-28克、夏枯草5-20克、香附子5-15克、淫羊藿5-28克、三七3-20克、草乌3-30克、生半夏5-15克、贝母3-30克、熟地3-30克、蒲公英5-30克、白芍5-30克、舌草3-28克、半枝莲5-25克、党参5-28克等药材备用；
(2)将备用的药材制成汤剂或粉剂；
(3)汤剂的制备步骤为：将药材放入药袋内并封闭袋口，将药袋放入6-8倍量的水中熬煮2-3小时；
(4)粉剂的制备步骤为：将药材放入粉碎机内混合粉碎，将粉碎后粉末过400目筛网筛出药粉。
本发明的有益效果是：针对性强，君臣佐使，科学配伍，用于软坚散结，激发巨噬细胞的活力，提高淋巴细胞转化率，抑制癌瘤细胞的生长、破坏肿瘤周围及癌灶内纤维蛋白凝集，阻止癌细胞着床，防止肿瘤的生长和转移。
具体实施方式
下面用具体实施例说明本发明，并不是对本发明的限制。
实施例一
将透骨草5克、甘草5克、当归5克、黄芪5克、夏枯草5克、香附子5克、淫羊藿5克、三七3克、草乌3克、生半夏5克、贝母3克、熟地3克、蒲公英5克、白芍5克、舌草3克、半枝莲5克、党参5克等药材备用；
将备用的药材制成汤剂或粉剂；汤剂的制备步骤为：将药材放入药袋内并封闭袋口，将药袋放入6-8倍量的水中熬煮2-3小时；粉剂的制备步骤为：将药材放入粉碎机内混合粉碎，将粉碎后粉末过400目筛网筛出药粉。
实施例二
将透骨草20克、甘草20克、当归20克、黄芪15克、夏枯草10克、香附子10克、淫羊藿15克、三七10克、草乌15克、生半夏10克、贝母15克、熟地15克、蒲公英20克、白芍20克、舌草15克、半枝莲15克、党参15克等药材备用；
将备用的药材制成汤剂或粉剂；汤剂的制备步骤为：将药材放入药袋内并封闭袋口，将药袋放入6-8倍量的水中熬煮2-3小时；粉剂的制备步骤为：将药材放入粉碎机内混合粉碎，将粉碎后粉末过400目筛网筛出药粉。
实施例三
将透骨草30克、甘草30克、当归30克、黄芪28克、夏枯草20克、香附子15克、淫羊藿28克、三七20克、草乌30克、生半夏15克、贝母30克、熟地30克、蒲公英30克、白芍30克、舌草28克、半枝莲25克、党参28克等药材备用；
将备用的药材制成汤剂或粉剂；汤剂的制备步骤为：将药材放入药袋内并封闭袋口，将药袋放入6-8倍量的水中熬煮2-3小时；粉剂的制备步骤为：将药材放入粉碎机内混合粉碎，将粉碎后粉末过400目筛网筛出药粉。
以上所述，仅为本发明较佳的具体实施方式，但本发明的保护范围并不局限于此，任何熟悉本技术领域的技术人员在本发明揭露的技术范围内，根据本发明的技术方案及其发明构思加以等同替换或改变，都应涵盖在本发明的保护范围之内。

Claims (2)

1.一种抗肿瘤中药组合物，其特征在于，包括以下重量份数的组分：透骨草5-30克、甘草5-30克、当归5-30克、黄芪5-28克、夏枯草5-20克、香附子5-15克、淫羊藿5-28克、三七3-20克、草乌3-30克、生半夏5-15克、贝母3-30克、熟地3-30克、蒲公英5-30克、白芍5-30克、舌草3-28克、半枝莲5-25克、党参5-28克等。
2.根据权利要求1所述的一种抗肿瘤中药组合物的制备方法，其特征在于，具体包括以下步骤：(1)取透骨草5-30克、甘草5-30克、当归5-30克、黄芪5-28克、夏枯草5-20克、香附子5-15克、淫羊藿5-28克、三七3-20克、草乌3-30克、生半夏5-15克、贝母3-30克、熟地3-30克、蒲公英5-30克、白芍5-30克、舌草3-28克、半枝莲5-25克、党参5-28克等药材备用；
(2)将备用的药材制成汤剂或粉剂；
(3)汤剂的制备步骤为：将药材放入药袋内并封闭袋口，将药袋放入6-8倍量的水中熬煮2-3小时；
(4)粉剂的制备步骤为：将药材放入粉碎机内混合粉碎，将粉碎后粉末过400目筛网筛出药粉。
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