CN112535283A - Total nutrient formula powder - Google Patents

Total nutrient formula powder Download PDF

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Publication number
CN112535283A
CN112535283A CN202011388124.3A CN202011388124A CN112535283A CN 112535283 A CN112535283 A CN 112535283A CN 202011388124 A CN202011388124 A CN 202011388124A CN 112535283 A CN112535283 A CN 112535283A
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China
Prior art keywords
powder
parts
microcapsule powder
vitamin
maltodextrin
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CN202011388124.3A
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高婷
李培兵
徐路
戴信敏
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Beijing Fahrenheit Kaiyuan Pharmaceutical Technology Co ltd
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Beijing Fahrenheit Kaiyuan Pharmaceutical Technology Co ltd
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Priority to CN202011388124.3A priority Critical patent/CN112535283A/en
Publication of CN112535283A publication Critical patent/CN112535283A/en
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/19—Dairy proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/113—Acidophilus
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/175—Rhamnosus
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/51—Bifidobacterium
    • A23V2400/515—Animalis

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pediatric Medicine (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention belongs to the field of food, and particularly relates to total nutrient formula powder, which is suitable for being aged more than or equal to 10 years and comprises the following raw materials in parts by weight: 20-32 parts of hydrolyzed whey protein, 14.5-34 parts of fat, 17-47.5 parts of carbohydrate, 4.5-6.5 parts of dietary fiber, 4-6 parts of mineral premix, 1-3 parts of vitamin premix and 0.5-2 parts of probiotic mixed powder; wherein the hydrolysis degree of the hydrolyzed whey protein is 30-40%; the strains of the probiotic mixed powder comprise bifidobacterium animalis BS01, lactobacillus rhamnosus LR04 and lactobacillus acidophilus. The total nutrient formula powder provided by the invention meets the requirements of people who are limited in eating, have metabolic disorder, have consumption and absorption disorder, are lactose intolerant, have normal gastrointestinal tract functions and are allergic to food protein on comprehensive nutrition under the synergistic effect of the hydrolyzed whey protein, the probiotics and other raw materials by a unique ratio.

Description

Total nutrient formula powder
Technical Field
The invention belongs to the field of food, and particularly relates to total nutrient formula powder.
Background
The formula food for special medical application is specially processed and prepared for meeting the special requirements of people with limited food intake, digestive absorption disorder, metabolic disorder or specific disease states on nutrients or diet. The product must be eaten alone or in combination with other foods under the guidance of doctors or clinical dieticians. The formula food for special medical application is only one way of providing nutrition support for clinical patients, and provides a selection mode for clinical nutrition support.
At present, people who are suitable for formula foods with special medical purposes are mostly directed to infants and people with specific diseases, such as people with diabetes, liver diseases and the like, but the requirements and the types of nutrition for different ages are different, and the formula foods for infants cannot be suitable for people with gastrointestinal function impairment and digestive function reduction more than 10 years old, so that the determination of the full-nutrition powder suitable for the people with gastrointestinal function impairment and digestive function reduction more than 10 years old is vital.
Disclosure of Invention
The invention provides a total nutrient formula powder, which meets the requirements of people who are limited in eating, disordered in metabolism, have consumption and absorption disorder, are lactose intolerant, have normal gastrointestinal tract functions and are allergic to food protein on comprehensive nutrition by unique proportion under the synergistic effect of raw materials such as hydrolyzed whey protein and probiotics.
The invention provides total nutrient formula powder, which is suitable for being aged more than or equal to 10 years and is characterized by comprising the following raw materials in parts by weight: 20-32 parts of hydrolyzed whey protein, 14.5-34 parts of fat, 17-47.5 parts of carbohydrate, 4.5-6.5 parts of dietary fiber, 4-6 parts of mineral premix, 1-3 parts of vitamin premix and 0.5-2 parts of probiotic mixed powder;
wherein the hydrolysis degree of the hydrolyzed whey protein is 30-40%;
the strains of the probiotic mixed powder comprise bifidobacterium animalis BS01, lactobacillus rhamnosus LR04 and lactobacillus acidophilus.
The deep hydrolyzed whey protein with the hydrolysis degree of 30-40% is added into the total nutrient formula powder, so that adverse reactions such as diarrhea, abdominal pain and the like caused by using whole protein are avoided, and the 30-40% deep hydrolyzed whey protein obtains more absorbable polypeptide and micromolecules and reduces the burden of the gastrointestinal tract; and intestinal flora state is improved by bifidobacterium animalis BS01, lactobacillus rhamnosus LR04 and lactobacillus acidophilus, so that under the synergistic effect of 30-40% of deeply hydrolyzed whey protein and raw materials such as bifidobacterium animalis BS01, lactobacillus rhamnosus LR04 and lactobacillus acidophilus, people with limited eating, metabolic disorder and consumption and absorption disorder of more than 10 years can absorb daily required full nutritional ingredients in the full nutritional formula powder consisting of hydrolyzed whey protein, fat, carbohydrate, dietary fiber, mineral premix, vitamin premix and probiotic mixed powder provided by the invention without the need of supplementing other foods. Furthermore, as the higher the hydrolysis degree of the hydrolyzed whey protein is, the bitter the taste is, the unique proportion of carbohydrate and dietary fiber is adopted in the invention, the taste of the full-nutrition formula powder is adjusted, the sweetness is suitable, no bitter taste exists, and essence, pigment and other additives are not required to be added. The total nutrient formula powder provided by the invention is a low-lactose formula, so that the total nutrient formula powder is suitable for lactose intolerant people over 10 years old, and is suitable for people with normal gastrointestinal tract function but allergy to food protein.
Detailed Description
In order to make the technical problems, technical solutions and advantageous effects to be solved by the present invention more clearly apparent, the present invention is further described in detail below with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
The embodiment of the invention provides total-nutrient formula powder, which is suitable for being aged more than or equal to 10 years and comprises the following raw materials in parts by weight: 20-32 parts of hydrolyzed whey protein, 14.5-34 parts of fat, 17-47.5 parts of carbohydrate, 4.5-6.5 parts of dietary fiber, 4-6 parts of mineral premix, 1-3 parts of vitamin premix and 0.5-2 parts of probiotic mixed powder;
wherein the hydrolysis degree of the hydrolyzed whey protein is 30-40%;
the strains of the probiotic mixed powder comprise bifidobacterium animalis BS01, lactobacillus rhamnosus LR04 and lactobacillus acidophilus.
The total nutrient formula powder provided by the embodiment is added with the deeply hydrolyzed whey protein with the hydrolysis degree of 30-40%, so that adverse reactions such as diarrhea and abdominal pain caused by using whole protein are avoided, the 30-40% of deeply hydrolyzed whey protein obtains more absorbable polypeptide and micromolecular protein and reduces the load of gastrointestinal tracts, the protein is easier to absorb as the higher the hydrolysis degree of the whey protein is, the proportion of molecules smaller than 1000Da in the hydrolyzed whey protein with the hydrolysis degree of about 10% is about 40%, and the proportion of molecules smaller than 1000Da in the hydrolyzed whey protein with the hydrolysis degree of 30% is higher than 80%, so that the deeply hydrolyzed whey protein in the embodiment is more easily absorbed; the intestinal flora state is improved through the bifidobacterium animalis BS01, the lactobacillus rhamnosus LR04 and the lactobacillus acidophilus, the impedance of intestinal tracts to the colonization of external harmful microorganisms is increased, and the intestinal flora is beneficially adjusted, so that the anabolism can be effectively promoted under the synergistic effect of 30-40% of deeply hydrolyzed whey protein and the raw materials of the bifidobacterium animalis BS01, the lactobacillus rhamnosus LR04 and the lactobacillus acidophilus, and the formula powder consisting of the hydrolyzed whey protein, fat, carbohydrate, dietary fiber, mineral substance premix, vitamin premix and probiotic mixed powder, which is limited in eating above 10 years old, disordered in metabolism and impaired in consumption and absorption, can be absorbed by people who consume and absorb the formula powder consisting of the hydrolyzed whey protein, the fat, the carbohydrate, the dietary fiber, the mineral substance premix, the vitamin premix and the probiotic mixed powder, and the nutritional status of. Further, since the hydrolyzed whey protein has higher degree of hydrolysis and bitter taste, the product taste is adjusted by adopting the unique ratio of carbohydrate to dietary fiber in the embodiment, the sweetness is suitable, no bitter taste exists, and no essence, pigment or other additives are added. The total nutrient formula powder provided by the embodiment is a low-lactose formula, so that the total nutrient formula powder provided by the embodiment is suitable for lactose intolerant people over 10 years old, and can be suitable for people with normal gastrointestinal tract function but allergy to food protein.
Further, the degree of hydrolysis of the hydrolyzed whey protein is 34% to 38%. The protein in the hydrolyzed whey protein mainly exists in the form of short peptide or amino acid, is more favorable for intestinal absorption compared with macromolecular protein, has the characteristics of low osmotic pressure, low antigenicity, good intestinal tolerance, direct and balanced absorption, and promotion of the utilization of nutrient substances by intestinal microorganisms and the absorption of amino acids and trace elements, integrally improves the digestion utilization rate of target people (people with food restriction, metabolic disorder, consumption and absorption disturbance, lactose intolerance, normal gastrointestinal tract function but food protein allergy) and corrects negative nitrogen balance, and does not cause gastrointestinal adverse reactions such as allergy, diarrhea and the like of the target people. In the embodiment, the hydrolysis degree of the hydrolyzed whey protein is controlled to be 34-38%, so that the hydrolyzed short peptides and amino acids can be better absorbed, and particularly when the hydrolysis degree of the extensively hydrolyzed whey protein is 38%, the absorption effect of the short peptides and amino acids is best, the allergenicity of the whey protein is obviously reduced, and the growth effect of each strain in the probiotic mixed powder is better.
Further, the ratio of the animal bifidobacterium BS01 to the lactobacillus rhamnosus LR04 to the lactobacillus acidophilus is 1:1:1, the auxiliary material of the probiotic mixed powder is polydextrose, and the number of the live probiotics is 5.0 x 1010And (4) CFU. The unique flora proportion adopted in the probiotic mixed powder provided by the embodiment can effectively increase the number of bifidobacteria and lactobacilli in intestinal tracts of target people, reduce the number of clostridium perfringens, enhance the resistance of the intestinal tracts of the target people to the colonization of external harmful microorganisms, and have beneficial regulation effect on the intestinal flora, and the regulation effect of the probiotic mixed powder provided by the embodiment on the intestinal flora is better than that of single probiotic.
Further, the fat is derived from at least one of sunflower seed oil, safflower seed oil, linseed oil, medium chain triglycerides, and fish oil; the carbohydrate is maltodextrin; the dietary fiber is fructo-oligosaccharide and/or resistant dextrin. In the embodiment, the carbohydrate is maltose, the dietary fiber is fructo-oligosaccharide and/or resistant dextrin, and the ratio of the carbohydrate to the dietary fiber is controlled to be 2.5-10.5, so that the bitterness of the deeply hydrolyzed whey protein can be effectively adjusted, and the obtained total nutrient formula powder has moderate sweetness and no bitterness. Preferably, the dietary fiber in the embodiment is fructo-oligosaccharide, and the probiotic mixed powder consisting of bifidobacterium animalis BS01, lactobacillus rhamnosus LR04 and lactobacillus acidophilus is added into the total nutrient formula powder, so that the proliferation of bifidobacterium animalis can be realized, the absorption of minerals such as Ca and Fe can be promoted, the synthesis of vitamins can be promoted, and when the addition amount of the fructo-oligosaccharide is 4.5-6.5%, the growth effect of the strains in the probiotic mixed powder is better, so that the intestinal flora state of a target population can be adjusted, and the nutritional status of the target population can be improved.
In the above embodiment, sunflower seed oil and safflower seed oil with high linoleic acid content, linseed oil with high linolenic acid content, rapidly energized medium chain triglyceride, and fish oil rich in omega-3 unsaturated fatty acids are used as fat source substances, so that the demand of the target population on the fat substances is ensured, and the health state of the target population is effectively improved.
Further, the following components are included in the fatty substance: 8-15 parts of sunflower seed oil microcapsule powder, 2-5 parts of linseed oil microcapsule powder and 8-14 parts of medium-chain triglyceride microcapsule powder. In this embodiment, the sources of the controlled fat substances are sunflower seed oil, linseed oil and medium-chain triglyceride, if the addition amount of the medium-chain triglyceride is too small, energy cannot be supplied quickly, and if the addition amount of the medium-chain triglyceride is too large, the health state of the target population cannot be guaranteed.
Further, the following components are included in the fatty substance: 8-15 parts of sunflower seed oil microcapsule powder, 2-5 parts of linseed oil microcapsule powder, 4-8 parts of medium-chain triglyceride microcapsule powder and 2-6 parts of fish oil microcapsule powder. The fatty acid proportions in different vegetable oils are different, so that the components of the fatty substances are required to be adjusted according to the requirement of the target population on the total fat content, so that the reasonable amount of linoleic acid, linolenic acid and omega-3 unsaturated fatty acid is provided for the target population while the rapid energy supply is ensured, and the health state of the target population is ensured.
Further, the following components are included in the fatty substance: 8-13 parts of safflower seed oil microcapsule powder, 2.5-5.5 parts of linseed oil microcapsule powder and 8-14 parts of medium-chain triglyceride microcapsule powder. The safflower seed oil is used for providing linoleic acid, and the requirement of target people on the fat content can be met under the proportion of the embodiment.
Further, the following components are included in the fatty substance: 8-13 parts of safflower seed oil microcapsule powder, 2.5-5.5 parts of linseed oil microcapsule powder, 4-8 parts of medium-chain triglyceride microcapsule powder and 2-6 parts of fish oil microcapsule powder. The requirement of target people on the fat amount can be met under the proportion of the embodiment.
Further, the total nutrient formula powder consists of the following components:
36.39% of maltodextrin; 25.04% of hydrolyzed whey protein; 11.824% of sunflower oil microcapsule powder; 2.956% of linseed oil microcapsule powder; 10.56% of medium chain triglyceride microcapsule powder; 5.23 percent of fructo-oligosaccharide; 5.5 percent of mineral premix; 1.5 percent of vitamin premix; 1% of probiotic mixed powder. In the embodiment, by controlling the addition amount of each substance, the intestinal state of the target population is effectively improved under the synergistic effect of the hydrolyzed whey protein, the fructo-oligosaccharide and the probiotic mixed powder, the number of bifidobacteria and lactobacilli in the intestinal tract of the target population is increased, the number of clostridium perfringens is reduced, the impedance to external harmful microorganism colonization is increased, and an effective regulation effect on the intestinal flora is achieved. The detection shows that the total nutrient formula powder food provided by the embodiment has protein more than or equal to 18g/100g, fat more than or equal to 13g/100g, linoleic acid energy supply ratio more than or equal to 4%, linolenic acid energy supply ratio more than or equal to 0.8% and carbohydrate more than or equal to 50; the vitamins and minerals all meet the requirements of special medical application formula food in the national standard of GB 29922 food safety.
The fat providing substance was improved over the above examples, wherein the maltodextrin was 36.39%; 25.04% of hydrolyzed whey protein; 11.824% of sunflower oil microcapsule powder; 2.956% of linseed oil microcapsule powder; 5.56% of medium chain triglyceride microcapsule powder; 5% of fish oil microcapsule powder; 5.23 percent of fructo-oligosaccharide; 5.5 percent of mineral premix; 1.5 percent of vitamin premix; 1% of probiotic mixed powder; in the embodiment, the health state of the target population can be ensured while the intestinal state of the target population can be improved.
The fat providing substance was improved over the above examples, wherein the maltodextrin was 36.39%; 25.04% of hydrolyzed whey protein; 10.824% of safflower seed oil microcapsule powder; 3.956% of linseed oil microcapsule powder; 10.56% of medium chain triglyceride microcapsule powder; 5.23 percent of fructo-oligosaccharide; 5.5 percent of mineral premix; 1.5 percent of vitamin premix; 1% of probiotic mixed powder. In the embodiment, the health state of the target population can be ensured while the intestinal state of the target population can be improved.
The fat providing substance was improved over the above examples, with 36.39% maltodextrin; 25.04% of hydrolyzed whey protein; 10.824% of safflower seed oil microcapsule powder; 3.956% of linseed oil microcapsule powder; 5.56% of medium chain triglyceride microcapsule powder; 5% of fish oil microcapsule powder; 5.23 percent of fructo-oligosaccharide; 5.5 percent of mineral premix; 1.5 percent of vitamin premix; 1% of probiotic mixed powder. In the embodiment, the health state of the target population can be ensured while the intestinal state of the target population can be improved.
Further, the total nutrient formula powder consists of the following components: 47.5% of maltodextrin; hydrolyzed whey protein 20%; 8% of sunflower seed oil microcapsule powder; 5% of linseed oil microcapsule powder; 8% of medium chain triglyceride microcapsule powder; 4.5 percent of fructo-oligosaccharide; 4% of mineral premix; 1% of vitamin premix; 2% of probiotic mixed powder. Through the research on the required amount of the nutrient substances and various nutrient substances needed by the target population, the proportion of each substance in the embodiment is determined, and under the proportion of the various substances provided by the embodiment, the intestinal state of the target population can be effectively improved, so that the target population can better absorb various nutrient substances, and the health state of the target population is ensured.
Further, the total nutrient formula powder consists of the following components: 17% of maltodextrin; 32% of hydrolyzed whey protein; 15% of sunflower seed oil microcapsule powder; 5% of linseed oil microcapsule powder; 15% of medium chain triglyceride microcapsule powder; 6.5 percent of fructo-oligosaccharide; 6% of mineral premix; 3% of vitamin premix; 0.5 percent of probiotic mixed powder. Under the proportion of the various materials that this embodiment provided, can effectual improvement target crowd's intestinal state for target crowd can carry out better absorption to various nutrients, has guaranteed target crowd's health.
Further, the total nutrient formula powder consists of the following components: 17% of maltodextrin; 32% of hydrolyzed whey protein; 15% of sunflower seed oil microcapsule powder; 5% of linseed oil microcapsule powder; 14% of medium chain triglyceride microcapsule powder; 5% of fish oil microcapsule powder; 4.5 percent of fructo-oligosaccharide; 5.5 percent of mineral premix; 1% of vitamin premix; 1% of probiotic mixed powder. Under the proportion of the various materials that this embodiment provided, can effectual improvement target crowd's intestinal state for target crowd can carry out better absorption to various nutrients, has guaranteed target crowd's health.
Further, the total nutrient formula powder consists of the following components: 44.5% of maltodextrin; hydrolyzed whey protein 20%; 8% of sunflower seed oil microcapsule powder; 2% of linseed oil microcapsule powder; 8% of medium chain triglyceride microcapsule powder; 5% of fish oil microcapsule powder; 4.5 percent of fructo-oligosaccharide; 4% of mineral premix; 3% of vitamin premix; 1% of probiotic mixed powder. Under the proportion of the various materials that this embodiment provided, can effectual improvement target crowd's intestinal state for target crowd can carry out better absorption to various nutrients, has guaranteed target crowd's health.
Further, the vitamin premix consists of the following components: maltodextrin 31.7% -68.208%; 20% -39% of choline bitartrate; 3% -10% of inositol; 3% -8% of L-carnitine tartrate; 3.5 to 7.5 percent of sodium ascorbate; 1% -4% of taurine; 0.8% -2.8% of vitamin E (50%); 0.1% -0.9% of nicotinamide; 0.1 to 0.6 percent of vitamin A acetate; 0.05 to 0.5 percent of D-calcium pantothenate; vitamin D3 (cholecalciferol) 0.05% -0.5%; vitamin B12 cyanocobalamin (0.1% in maltodextrin) 0.05% -0.5%; folic acid (10% maltodextrin) 0.05% -0.5%; 0.05% -0.45% of D-biotin (1% in maltodextrin); 0.02% -0.45% of vitamin B1 (thiamine hydrochloride); 0.01% -0.45% of vitamin B6 (pyridoxine hydrochloride); 0.01% -0.45% of vitamin B2 (riboflavin); 0.001% -0.35% of vitamin K1 (5%); potassium iodide (10% in maltodextrin) 0.001% -0.35%.
In the embodiment, after a great deal of research is carried out on the types and the contents of the vitamins required by the target population, the types and the contents of the vitamin premix are determined, and if the contents of certain vitamins are too low to meet the demand of the target population, the target population is required to be matched with other foods for eating, so that the types and the contents of the vitamins provided by the embodiment can meet the demand of the target population on the vitamins and can be well absorbed. Specifically, the vitamin premix comprises the following components: 52.7275% of maltodextrin; 25.6078% of choline bitartrate; 6.3333% of inositol; 4.8851% L-carnitine tartrate; sodium ascorbate 4.2442%; taurine 2.0000%; vitamin E (50%) 1.7880%; 0.4563% of nicotinamide; 0.3282% of vitamin A acetate; 0.2802% of D-calcium pantothenate; vitamin D3 (cholecalciferol) 0.2400%; vitamin B12 cyanocobalamin (0.1% in maltodextrin) 0.2133%; folic acid (10% maltodextrin) 0.2133%; d-biotin (1% in maltodextrin) 0.1887%; vitamin B1 (thiamine hydrochloride) 0.1310%; vitamin B6 (pyridoxine hydrochloride) 0.1220%; vitamin B2 (riboflavin) 0.1000%; vitamin K1 (5%) 0.0800%; 0.0610% potassium iodide (10% in maltodextrin). The variety and the content of the vitamins are reasonably prepared, so that the nutritional density of the total nutrient formula powder can be improved, the requirements of target people on the vitamins can be met, and diseases caused by vitamin deficiency can be reduced and prevented.
Further, the mineral premix consists of the following components: 15% -22% of monopotassium phosphate; 15% -21% of calcium carbonate; 15% -21% of sodium chloride; 1.2% -35.68% of maltodextrin; 10 to 17 percent of magnesium sulfate (dry product); 9% -15% of potassium citrate-monohydrate; potassium pyrophosphate 0.1% -1%; manganese sulfate-water (10% in maltodextrin) 0.08% -0.45%; 0.06% -0.35% of zinc sulfate monohydrate; sodium selenite (1% in maltodextrin) 0.05% -0.6%; 0.03 to 0.4 percent of copper sulfate. In this example, after a great deal of research on the desired mineral content of the target population, the types and contents of the minerals are determined to meet the needs of the target population. Specifically, the mineral premix comprises the following components: potassium dihydrogen phosphate 18.7636; 18.6168% of calcium carbonate; 18.4612% of sodium chloride; 16.4669% of maltodextrin; 13.6567% magnesium sulfate (dried product); potassium citrate-12.7481% monohydrate; 0.4800% of potassium pyrophosphate; 0.2467% manganese sulfate-water (10% in maltodextrin); 0.2395% of zinc sulfate monohydrate; 0.1991% sodium selenite (1% in maltodextrin); 0.1212 percent of copper sulfate and reasonable preparation of the types and the contents of the minerals, meets the requirements of target people on the minerals, does not need to be matched with other foods for eating, and ensures the health status of the target people.
On the other hand, the embodiment of the invention also provides a preparation method of the total nutrient formula powder, which comprises the following steps:
step S10: weighing, namely weighing the raw materials according to the formula amount for later use;
step S20: premixing, namely putting the deeply hydrolyzed whey protein and maltodextrin into a 800L hopper, and premixing for 5min under the condition of 12rpm to obtain premixed powder;
step S30: totally mixing, namely putting materials into a 800L hopper according to the sequence of safflower seed oil microcapsule powder (sunflower safflower seed oil microcapsule powder), fructo-oligosaccharide, vitamin premix, medium-chain triglyceride microcapsule powder and/or fish oil microcapsule powder, mineral premix, linseed oil microcapsule powder and probiotic mixed powder in the premixed powder, and totally mixing for 5min under the condition of 12rpm to obtain total mixed powder;
step S40: and (4) packaging, namely packaging (filling) the qualified total mixed powder in an inner package mode at the packaging machine speed of 10-20 barg/min, and then carrying out outer package to obtain a finished product.
The state, the uniformity and the effect of the finally obtained full-nutrition formula powder are different due to different feeding sequences, the quality of the product can be directly influenced, under the feeding sequence and the preparation conditions of the embodiment, the faint yellow to yellow powder can be obtained, the formula powder which is free of visible foreign impurities, agglomeration, peculiar smell and good in uniformity and has unique flavor can be obtained, the synergistic effect of all substances in the formula powder is good, the intestinal state of a target group is obviously improved, and the requirements of the target group on various nutritional ingredients are met.
The invention is described in further detail with reference to a part of the test results, which are described in detail below with reference to specific examples.
Example 1
The total nutrient formula powder comprises the following components in percentage by mass as shown in table 1:
TABLE 1
Figure BDA0002810367350000091
Figure BDA0002810367350000101
Wherein, the vitamin premix comprises the components with the percentage shown in the table 2:
TABLE 2
Name (R) Content (%)
Maltodextrin 52.7275
Choline bitartrate 25.6078
Inositol 6.3333
L-carnitine tartrate 4.8851
Ascorbic acid sodium salt 4.2442
Taurine 2.0000
Vitamin E (dl-a-tocopheryl acetate) 50% 1.7880
Nicotinamide 0.4563
Vitamin A acetate 325000IU 0.3282
D-calcium pantothenate 0.2802
Vitamin D3(Cholcidol) 100000IU 0.2400
Vitamin B12Cyanocobalamin (0.1% in maltodextrin) 0.2133
Folic acid (10% maltodextrin) 0.2133
D-Biotin (1% in maltodextrin) 0.1887
Vitamin B1(thiamine hydrochloride) 0.1310
Vitamin B6(pyridoxine hydrochloride) 0.1220
Vitamin B2(Riboflavin) 0.1000
Vitamin K1 5％ 0.0800
Potassium iodide (10% in maltodextrin) 0.0610
The mineral premix comprises the components in percentage as shown in table 3:
TABLE 3
Figure BDA0002810367350000102
Figure BDA0002810367350000111
The preparation method of the total nutrient powder comprises the following steps:
step S10: weighing, preparing a mineral premix and a vitamin premix according to the formula shown in tables 2 and 3, and weighing the raw materials according to the formula shown in table 1 for later use;
step S20: premixing, namely putting 25.04 parts of deeply hydrolyzed whey protein (hydrolysis degree of 38%) and 36.39 parts of maltodextrin into a 800L hopper, and premixing for 5min under the condition of 12rpm to obtain premixed powder;
step S30: total mixing, namely adding 11.824 parts of sunflower seed oil microcapsule powder, 5.23 parts of fructo-oligosaccharide, 1.5 parts of vitamin premix, 5.56 parts of medium chain triglyceride microcapsule powder, 5 parts of fish oil microcapsule powder, 5.5 parts of mineral premix, 2.956 parts of linseed oil microcapsule powder and 1 part of probiotic mixed powder into the premixed powder in sequence, and then putting the materials into a 800L hopper to be mixed for 5min under the condition of 12rpm to obtain total mixed powder;
step S40: and (4) packaging, namely packaging (filling) the total mixed powder after the total mixed powder is inspected to be qualified, wherein the speed of a packaging machine is 15 barg/min, and then externally packaging to obtain a finished product.
The total nutrient formula powder provided in this example was evaluated: the influence of the total nutrient formula of the embodiment on the immune function of the red blood cells of the mice is evaluated by an animal experiment; clinical tests are utilized to evaluate the special application effect of the total nutrient formula powder on clinically severe patients.
Animal experiment evaluation method: half of Kunming mice (purchased from Beijing Wittiulihua laboratory animal technology Co., Ltd.) with the body weight of 18g-20g are selected and randomly grouped. The administration mode comprises the following steps: and (5) performing intragastric administration. The blank group was given physiological saline, the control group mice were given the ordinary total nutrient formula powder (whole protein probiotic-free formula), and the experimental group mice were given the total nutrient formula powder. The mouse retrobulbar plexus red blood cell (C3b) receptor rosette (E-C3bR), red blood cell immune complex rosette (E-ICR) and tumor red blood cell rosette (T-RR) were tested once a day for seven consecutive days, and the results are shown in Table 4. The formula of the common total nutrient formula powder is as follows: starch sugar (solid glucose syrup), maltodextrin, sunflower seed oil, sodium caseinate, white granulated sugar, calcium caseinate, inulin fructo-oligosaccharide mixture (inulin, fructo-oligosaccharide), soybean oil, soy protein isolate, milk protein isolate, rapeseed oil, vitamin a palmitate, vitamin D3, dl-alpha-tocopherol acetate, mixed tocopherol concentrate, phytomenadione, thiamine hydrochloride, riboflavin, pyridoxine hydrochloride, cyanocobalamin, nicotinamide, folic acid, D-calcium pantothenate, L-ascorbic acid, ascorbyl palmitate, D-biotin, sodium citrate, sodium chloride, potassium citrate, potassium chloride, copper sulfate, magnesium chloride, magnesium hydrogen phosphate, ferrous sulfate, ferric pyrophosphate, zinc sulfate, manganese sulfate, tricalcium phosphate, potassium iodide, sodium selenate, chromium chloride, sodium molybdate, choline chloride, beta-carotene, phospholipid, flavoring essence and spice (flavoring essence and vanillin), calcium carbonate, dipotassium hydrogen phosphate, L-sodium ascorbate, citric acid and potassium hydroxide.
TABLE 4 Effect of the nutritionally complete formula of this example on the binding rate of the three rosettes
Figure BDA0002810367350000121
As can be seen from table 4, the total nutrient formula powder of this example has a significant effect of promoting the formation of three rosettes, and is higher than the common total nutrient formula powder (whole protein probiotic-free formula).
And (3) clinical trials: 29 patients with age greater than or equal to 10 age with clinical gastrointestinal absorption dysfunction and malnutrition were selected, and the body weight, serum albumin, transferrin, pre-albumin, creatinine, and serum albumin were measured before, after 15 days of nutritional support and 30 days of nutritional support, respectively, before and after administration of the total nutritional formula powder of this example, and the results of the experiment are shown in table 5:
TABLE 5 patient nutritional support before and after relevant index changes
Figure BDA0002810367350000122
Figure BDA0002810367350000131
As can be seen from Table 5, the body weight, serum albumin and creatinine were not significantly changed (p > 0.05) after 15 days of nutritional support, and transferrin and pre-albumin were significantly increased (p < 0.05); after 30 days, the change difference of the body weight and the creatinine is obvious (p is less than 0.05), the change difference of the procalbumin, the transferrin and the serum albumin is obviously increased, and the change difference is extremely obvious (p is less than 0.01) compared with that before the nutrition support, in addition, no vomit, reflux and aspiration occur during the taking period of 29 patients, and the diarrhea of part of the patients with the diarrhea condition is also improved, so the total nutrient formula powder can effectively promote the anabolism and improve the nutrition condition of the patients.
Furthermore, 20 clinical adults with lactose intolerance were selected, and the total nutrient formula powder provided by the embodiment was continuously taken for 30 days, six times a day, and 80g each time. Lactose absorption was evaluated by Hydrogen Breath Test (HBT) and the incidence of abdominal distension, diarrhea, skin eczema was also observed. HBT is positive, which indicates lactose malabsorption, HBT is positive, and lactose intolerance occurs in patients with any symptoms of abdominal distension, abdominal pain and diarrhea, and the experimental results are shown in Table 6:
TABLE 6 comparison of results before and after nutritional support for lactose intolerant patients
Index (I) Results p
HBT Negative of ＜0.01
Abdominal distention Is free of ＜0.05
Diarrhea (diarrhea) Is free of ＜0.01
Abdominal pain Is free of ＜0.05
As can be seen from table 6, the HBTs of the subjects were negative and did not develop any symptom of abdominal distension, diarrhea, and abdominal pain, and none of the subjects developed lactose intolerance, so it can be seen that the total nutritional formula powder provided in this example is suitable for lactose intolerant patients.
According to results of animal experiments and clinical tests, the total nutrient formula powder provided by the embodiment can improve the immunity of the organism, improve the nutritional status and avoid lactose intolerance.
Animal evaluation test data of effect of probiotic mixed powder on regulating intestinal flora
Experimental groups: self-made probiotic mixed powder (the ratio of bifidobacterium animalis BS01, lactobacillus rhamnosus LR04 and lactobacillus acidophilus is 1:1:1, and the auxiliary material of the probiotic mixed powder is polydextrose); blank control group: a placebo; positive control group 1: a group of Bifidobacterium animalis; positive control 2 group: lactobacillus acidophilus group; positive control group 3: lactobacillus rhamnosus group.
18 g-22 g male SPF-grade healthy Balb/c mice (purchased from Beijing Wittingle laboratory animal technology Co., Ltd.) are randomly grouped, 10 mice in each group are subjected to intragastric administration for 14d, 0d, 7d and 14d mouse feces are collected, and the number of bifidobacteria, lactobacillus, enterobacteria and clostridium perfringens in the feces and the ratio (B/E value) of the bifidobacteria to the enterobacteria are counted by plate culture after gradient dilution. The results of the experiments are shown in tables 7 to 11:
TABLE 7 live Bifidobacterium in intestinal tract of mice: (
Figure BDA0002810367350000141
n＝10)
Figure BDA0002810367350000142
From table 7, it can be seen that the viable count of bifidobacterium in the intestinal tract of the mouse is changed, and the viable count of bifidobacterium in the intestinal tract of the mouse 7 days after the intervention of the probiotic mixed powder in the experimental group is significantly higher than that in the blank control group (P is less than 0.05), which indicates that the probiotic mixed powder has the effect of increasing the number of bifidobacterium in the intestinal tract of the mouse and the effect is better than that of the positive control group.
TABLE 8 viable intestinal Lactobacillus count in mice: (
Figure BDA0002810367350000143
n＝10)
Figure BDA0002810367350000144
Figure BDA0002810367350000151
From Table 8, it can be seen that the number of live intestinal lactobacilli in mice is changed, and the number of live intestinal lactobacilli in mice of positive control group 2 and positive control group 3 on day 14 is significantly higher than that before the experiment (0d, P < 0.05); on the 7 th day after the intervention of the experimental group, the number of the live lactobacillus is obviously higher than that of the blank control group (P is less than 0.05), which indicates that the probiotic mixed powder of the experimental group has the function of increasing the number of the lactobacillus in the intestinal tract of the mouse, and the effect is better than that of the positive control group.
TABLE 9 number of live Enterobacter entericus in mice: (
Figure BDA0002810367350000152
n＝10)
Figure BDA0002810367350000153
It can be seen from table 9 that the change of viable bacteria amount of enterobacter intestinal tract of mice, comparison of self change before and after the experiment of viable bacteria amount of enterobacter faecalis of each group of mice and comparison difference between groups at the same time point have no statistical significance, which indicates that the mixed probiotic powder has no influence on the amount of enterobacter intestinal tract of mice.
TABLE 10 number of live bacteria of Clostridium perfringens in mouse intestinal tract ((S))
Figure BDA0002810367350000154
n＝10)
Figure BDA0002810367350000155
From table 10, it can be seen that the number of live clostridium perfringens in the intestinal tract of the mouse is changed, and the number of live clostridium perfringens in the intestinal tract of the mouse is significantly lower than that before the experiment (0d, P is less than 0.05) on the 7 th day after the intervention of the probiotic mixed powder of the experimental group, which indicates that the probiotic mixed powder has the effect of reducing the number of clostridium perfringens in the intestinal tract of the mouse.
Table 11 mice intestinal bifidobacterium to enterobacter ratios (B/E,
Figure BDA0002810367350000161
n＝10)
Figure BDA0002810367350000162
from Table 11, it can be seen that the ratio of Bifidobacterium enterobacter to Enterobacter enterobacter (B/E) of the mice was changed, and the B/E value of the intestinal tract of the mice in the blank control group was significantly higher than that before the experiment (0d, P < 0.05) at 7 days after the experiment; after the probiotic mixed powder is intervened for 14 days in the experimental group, the B/E value of the intestinal tract of the mouse is obviously higher than that of a blank control group and a positive control group (P is less than 0.05), and the probiotic mixed powder can enhance the colonization resistance of intestinal microorganisms of the mouse and has the potential of regulating the intestinal flora.
In conclusion, the animal evaluation test data of the effect of the probiotic mixed powder on regulating the intestinal flora shows that the probiotic mixed powder can increase the number of bifidobacteria and lactobacilli in intestinal tracts of mice and reduce the number of clostridium perfringens. The B/E value is the ratio of the number of bifidobacteria to the number of enterobacteria, and this indicator can be used to evaluate the resistance of the organism to colonization of the intestinal tract by foreign microorganisms. The bifidobacterium is a representative of beneficial bacteria in the intestinal tract, the enterobacteria is considered as a predictive factor for the transformation of the intestinal flora to a harmful effect direction, the ratio of the bifidobacterium to the enterobacteria can reflect the structure of the intestinal flora in a beneficial and harmful way, after the intervention of the probiotic mixed powder of the experimental group for 14 days, the B/E value of the intestinal tract of the mouse is obviously higher than that of a blank control group, which shows that the probiotic mixed powder of the experimental group can enhance the resistance of the intestinal tract of the mouse to the colonization of external harmful microorganisms and has a beneficial regulation effect on the intestinal flora.
Example 2
The total nutrient formula powder comprises the following components in percentage by mass as shown in table 12:
TABLE 12
Name of raw materials The product addition amount is g/100g
Maltodextrin 36.39
Deeply hydrolyzed whey protein 25.04
Safflower seed oil microcapsule powder 10.824
Linseed oil microcapsule powder 3.956
Fish oil microcapsule powder 5
Medium chain triglyceride microcapsule powder 5.56
Fructo-oligosaccharide 5.23
Mineral premix 5.5
Vitamin premix 1.5
Probiotic mixed powder 1
The preparation method of the total nutrient powder comprises the following steps:
step S10: weighing, weighing the raw materials according to the formula amount shown in table 12 for later use (the components of the mineral premix and the vitamin premix are the same as those in example 1);
step S20: premixing, namely putting 25.04 parts of deeply hydrolyzed whey protein (hydrolysis degree of 38%) and 36.39 parts of maltodextrin into a 800L hopper, and premixing for 5min under the condition of 12rpm to obtain premixed powder;
step S30: total mixing, namely adding 10.824 parts of safflower seed oil microcapsule powder, 5.23 parts of fructo-oligosaccharide, 1.5 parts of vitamin premix, 5.56 parts of medium chain triglyceride microcapsule powder, 5 parts of fish oil microcapsule powder, 5.5 parts of mineral premix, 3.956 parts of linseed oil microcapsule powder and 1 part of probiotic mixed powder into the premixed powder in sequence, and then putting the materials into a 800L hopper to be mixed for 5min under the condition of 12rpm to obtain total mixed powder;
step S40: and (4) packaging, namely packaging (filling) the total mixed powder after the total mixed powder is inspected to be qualified, wherein the speed of a packaging machine is 15 barg/min, and then externally packaging to obtain a finished product.
Example 3
The total nutrient formula powder comprises the following components in percentage by mass as shown in Table 13:
watch 13
Figure BDA0002810367350000171
Figure BDA0002810367350000181
The preparation method of the total nutrient powder comprises the following steps:
step S10: weighing, weighing the raw materials according to the formula amount shown in table 13 for later use (the components of the mineral premix and the vitamin premix are the same as those in example 1);
step S20: premixing, namely putting 25.04 parts of deeply hydrolyzed whey protein (the hydrolysis degree is 30%) and 36.39 parts of maltodextrin into a 800L hopper, and premixing for 5min under the condition of 12rpm to obtain premixed powder;
step S30: total mixing, namely adding 10.824 parts of safflower seed oil microcapsule powder, 5.23 parts of fructo-oligosaccharide, 1.5 parts of vitamin premix, 10.56 parts of medium chain triglyceride microcapsule powder, 5.5 parts of mineral premix, 3.956 parts of linseed oil microcapsule powder and 1 part of probiotic mixed powder into the premixed powder in sequence, and then putting the materials into a 800L hopper to be mixed for 5min under the condition of 12rpm to obtain total mixed powder;
step S40: and (4) packaging, namely packaging (filling) the total mixed powder after the total mixed powder is inspected to be qualified, wherein the speed of a packaging machine is 15 barg/min, and then externally packaging to obtain a finished product.
Example 4
The total nutrient formula powder comprises the following components in percentage by mass as shown in table 14:
TABLE 14
Figure BDA0002810367350000182
Figure BDA0002810367350000191
The preparation method of the total nutrient powder comprises the following steps:
step S10: weighing, weighing the raw materials according to the formula amount shown in table 14 for standby (the components of the mineral premix and the vitamin premix are the same as those in example 1);
step S20: premixing, namely putting 25.04 parts of deeply hydrolyzed whey protein (hydrolysis degree of 38%) and 36.39 parts of maltodextrin into a 800L hopper, and premixing for 5min under the condition of 12rpm to obtain premixed powder;
step S30: total mixing, namely adding 11.824 parts of sunflower seed oil microcapsule powder, 5.23 parts of fructo-oligosaccharide, 1.5 parts of vitamin premix, 10.56 parts of medium chain triglyceride microcapsule powder, 5.5 parts of mineral premix, 2.956 parts of linseed oil microcapsule powder and 1 part of probiotic mixed powder into the premixed powder in sequence, and then putting the materials into a 800L hopper to be mixed for 5min under the condition of 12rpm to obtain total mixed powder;
step S40: and (4) packaging, namely packaging (filling) the total mixed powder after the total mixed powder is inspected to be qualified, wherein the speed of a packaging machine is 15 barg/min, and then externally packaging to obtain a finished product.
Example 5
The total nutrient formula powder comprises the following components in percentage by mass as shown in table 15:
watch 15
Name of raw materials The product addition amount is g/100g
Maltodextrin 47.5
Deeply hydrolyzed whey protein 20
Sunflower seed oil microcapsule powder 8
Linseed oil microcapsule powder 5
Medium chain triglyceride microcapsule powder 8
Fructo-oligosaccharide 4.5
Mineral premix 4
Vitamin premix 1
Probiotic mixed powder 2
The preparation method of the total nutrient powder comprises the following steps:
step S10: weighing, weighing the raw materials according to the formula amount shown in table 15 for standby (the components of the mineral premix and the vitamin premix are the same as those in example 1);
step S20: premixing, namely putting 20 parts of deeply hydrolyzed whey protein (the hydrolysis degree is 34%) and 47.5 parts of maltodextrin into a 800L hopper, and premixing for 5min under the condition of 12rpm to obtain premixed powder;
step S30: the method comprises the following steps of (1) totally mixing, namely adding 8 parts of sunflower seed oil microcapsule powder, 4.5 parts of fructo-oligosaccharide, 1 part of vitamin premix, 8 parts of medium-chain triglyceride microcapsule powder, 4 parts of mineral premix, 5 parts of linseed oil microcapsule powder and 2 parts of probiotic mixed powder into premixed powder in sequence, and then putting the materials into a 800L hopper to be totally mixed for 5min under the condition of 12rpm to obtain total mixed powder;
step S40: and (4) packaging, namely packaging (filling) the total mixed powder after the total mixed powder is inspected to be qualified, wherein the speed of a packaging machine is 15 barg/min, and then externally packaging to obtain a finished product.
Example 6
The total nutrient formula powder comprises the following components in percentage by mass as shown in table 16:
TABLE 16
Name of raw materials The product addition amount is g/100g
Maltodextrin 17
Deeply hydrolyzed whey protein 32
Sunflower seed oil microcapsule powder 15
Linseed oil microcapsule powder 5
Medium chain triglyceride microcapsule powder 15
Fructo-oligosaccharide 6.5
Mineral premix 6
Vitamin premix 3
Probiotic mixed powder 0.5
The preparation method of the total nutrient powder comprises the following steps:
step S10: weighing, weighing the raw materials according to the formula amount shown in table 16 for standby (the components of the mineral premix and the vitamin premix are the same as those in example 1);
step S20: premixing, namely putting 32 parts of deeply hydrolyzed whey protein (the hydrolysis degree is 40%) and 17 parts of maltodextrin into a 800L hopper, and premixing for 5min under the condition of 12rpm to obtain premixed powder;
step S30: the method comprises the following steps of (1) totally mixing, namely adding 15 parts of sunflower seed oil microcapsule powder, 6.5 parts of fructo-oligosaccharide, 3 parts of vitamin premix, 15 parts of medium-chain triglyceride microcapsule powder, 6 parts of mineral premix, 5 parts of linseed oil microcapsule powder and 0.5 part of probiotic mixed powder into premixed powder in sequence, and then putting the materials into a 800L hopper to be totally mixed for 5min under the condition of 12rpm to obtain total mixed powder;
step S40: and (4) packaging, namely packaging (filling) the total mixed powder after the total mixed powder is inspected to be qualified, wherein the speed of a packaging machine is 15 barg/min, and then externally packaging to obtain a finished product.
Example 7
The total nutrient formula powder comprises the following components in percentage by mass as shown in table 17:
TABLE 17
Name of raw materials The product addition amount is g/100g
Maltodextrin 17
Deeply hydrolyzed whey protein 32
Sunflower seed oil microcapsule powder 15
Linseed oil microcapsule powder 5
Medium chain triglyceride microcapsule powder 14
Fish oil microcapsule powder 5
Fructo-oligosaccharide 4.5
Mineral premix 5.5
Vitamin premix 1
Probiotic mixed powder 1
The preparation method of the total nutrient powder comprises the following steps:
step S10: weighing, weighing the raw materials according to the formula amount shown in table 17 for later use (the components of the mineral premix and the vitamin premix are the same as those in example 1);
step S20: premixing, namely putting 32 parts of deeply hydrolyzed whey protein (the hydrolysis degree is 38%) and 17 parts of maltodextrin into a 800L hopper, and premixing for 5min under the condition of 12rpm to obtain premixed powder;
step S30: the preparation method comprises the following steps of (1) totally mixing, namely adding 15 parts of sunflower seed oil microcapsule powder, 4.5 parts of fructo-oligosaccharide, 1 part of vitamin premix, 14 parts of medium-chain triglyceride microcapsule powder, 5 parts of fish oil microcapsule powder, 5.5 parts of mineral premix, 5 parts of linseed oil microcapsule powder and 1 part of probiotic mixed powder into premixed powder in sequence, and then putting the materials into a 800L hopper to be totally mixed for 5min under the condition of 12rpm to obtain total mixed powder;
step S40: and (4) packaging, namely packaging (filling) the total mixed powder after the total mixed powder is inspected to be qualified, wherein the speed of a packaging machine is 15 barg/min, and then externally packaging to obtain a finished product.
Example 8
The total nutrient formula powder comprises the following components in percentage by mass as shown in table 18:
watch 18
Name of raw materials The product addition amount is g/100g
Maltodextrin 44.5
Deeply hydrolyzed whey protein 20
Sunflower seed oil microcapsule powder 8
Linseed oil microcapsule powder 2
Medium chain triglyceride microcapsule powder 8
Fish oil microcapsule powder 5
Fructo-oligosaccharide 4.5
Mineral premix 4
Vitamin premix 3
Probiotic mixed powder 1
The preparation method of the total nutrient powder comprises the following steps:
step S10: weighing, weighing the raw materials according to the formula amount shown in table 18 for standby (the components of the mineral premix and the vitamin premix are the same as those in example 1);
step S20: premixing, namely putting 20 parts of deeply hydrolyzed whey protein (the hydrolysis degree is 38%) and 44.5 parts of maltodextrin into a 800L hopper, and premixing for 5min under the condition of 12rpm to obtain premixed powder;
step S30: the method comprises the following steps of (1) totally mixing, namely adding 8 parts of sunflower seed oil microcapsule powder, 4.5 parts of fructo-oligosaccharide, 3 parts of vitamin premix, 8 parts of medium-chain triglyceride microcapsule powder, 5 parts of fish oil microcapsule powder, 4 parts of mineral premix, 2 parts of linseed oil microcapsule powder and 1 part of probiotic mixed powder into premixed powder in sequence, and then putting the materials into a 800L hopper to be totally mixed for 5min under the condition of 12rpm to obtain total mixed powder;
step S40: and (4) packaging, namely packaging (filling) the total mixed powder after the total mixed powder is inspected to be qualified, wherein the speed of a packaging machine is 15 barg/min, and then externally packaging to obtain a finished product.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention are intended to be included within the scope of the present invention.

Claims (10)

1. A full-nutrition formula powder is suitable for being aged more than or equal to 10 years, and is characterized by comprising the following raw materials in parts by weight: 20-32 parts of hydrolyzed whey protein, 14.5-34 parts of fat, 17-47.5 parts of carbohydrate, 4.5-6.5 parts of dietary fiber, 4-6 parts of mineral premix, 1-3 parts of vitamin premix and 0.5-2 parts of probiotic mixed powder;
wherein the hydrolysis degree of the hydrolyzed whey protein is 30-40%;
the strains of the probiotic mixed powder comprise bifidobacterium animalis BS01, lactobacillus rhamnosus LR04 and lactobacillus acidophilus.
2. The nutritionally complete formula according to claim 1, wherein said hydrolyzed whey protein has a degree of hydrolysis of 34% to 38%.
3. The total nutritional formula powder according to claim 1, wherein the ratio of bifidobacterium animalis BS01, lactobacillus rhamnosus LR04 and lactobacillus acidophilus is 1:1:1, and the auxiliary material of the probiotic mixed powder is polydextrose.
4. The nutritionally complete formula according to claim 1, wherein said fat is derived from at least one of sunflower oil, safflower oil, linseed oil, medium chain triglycerides, fish oil;
the carbohydrate is maltodextrin;
the dietary fiber is fructo-oligosaccharide and/or resistant dextrin.
5. The nutritionally complete formula according to claim 4, wherein said fatty material comprises the following components:
8-15 parts of sunflower seed oil microcapsule powder, 2-5 parts of linseed oil microcapsule powder and 8-14 parts of medium-chain triglyceride microcapsule powder;
or 8-15 parts of sunflower seed oil microcapsule powder, 2-5 parts of linseed oil microcapsule powder, 4-8 parts of medium-chain triglyceride microcapsule powder and 2-6 parts of fish oil microcapsule powder;
or 8-13 parts of safflower seed oil microcapsule powder, 2.5-5.5 parts of linseed oil microcapsule powder and 8-14 parts of medium-chain triglyceride microcapsule powder;
or 8-13 parts of safflower seed oil microcapsule powder, 2.5-5.5 parts of linseed oil microcapsule powder, 4-8 parts of medium-chain triglyceride microcapsule powder and 2-6 parts of fish oil microcapsule powder.
6. The nutritionally complete formula according to claim 1, wherein said nutritionally complete formula consists of:
36.39% of maltodextrin; 25.04% of hydrolyzed whey protein; 11.824% of sunflower oil microcapsule powder; 2.956% of linseed oil microcapsule powder; 10.56% of medium chain triglyceride microcapsule powder; 5.23 percent of fructo-oligosaccharide; 5.5 percent of mineral premix; 1.5 percent of vitamin premix; 1% of probiotic mixed powder;
or, maltodextrin 36.39%; 25.04% of hydrolyzed whey protein; 11.824% of sunflower oil microcapsule powder; 2.956% of linseed oil microcapsule powder; 5.56% of medium chain triglyceride microcapsule powder; 5% of fish oil microcapsule powder; 5.23 percent of fructo-oligosaccharide; 5.5 percent of mineral premix; 1.5 percent of vitamin premix; 1% of probiotic mixed powder;
or, maltodextrin 36.39%; 25.04% of hydrolyzed whey protein; 10.824% of safflower seed oil microcapsule powder; 3.956% of linseed oil microcapsule powder; 10.56% of medium chain triglyceride microcapsule powder; 5.23 percent of fructo-oligosaccharide; 5.5 percent of mineral premix; 1.5 percent of vitamin premix; 1% of probiotic mixed powder;
or, maltodextrin 36.39%; 25.04% of hydrolyzed whey protein; 10.824% of safflower seed oil microcapsule powder; 3.956% of linseed oil microcapsule powder; 5.56% of medium chain triglyceride microcapsule powder; 5% of fish oil microcapsule powder; 5.23 percent of fructo-oligosaccharide; 5.5 percent of mineral premix; 1.5 percent of vitamin premix; 1% of probiotic mixed powder;
or, 47.5% maltodextrin; hydrolyzed whey protein 20%; 8% of sunflower seed oil microcapsule powder; 5% of linseed oil microcapsule powder; 8% of medium chain triglyceride microcapsule powder; 4.5 percent of fructo-oligosaccharide; 4% of mineral premix; 1% of vitamin premix; 2% of probiotic mixed powder;
or, maltodextrin 17%; 32% of hydrolyzed whey protein; 15% of sunflower seed oil microcapsule powder; 5% of linseed oil microcapsule powder; 15% of medium chain triglyceride microcapsule powder; 6.5 percent of fructo-oligosaccharide; 6% of mineral premix; 3% of vitamin premix; 0.5 percent of probiotic mixed powder;
or, maltodextrin 17%; 32% of hydrolyzed whey protein; 15% of sunflower seed oil microcapsule powder; 5% of linseed oil microcapsule powder; 14% of medium chain triglyceride microcapsule powder; 5% of fish oil microcapsule powder; 4.5 percent of fructo-oligosaccharide; 5.5 percent of mineral premix; 1% of vitamin premix; 1% of probiotic mixed powder;
or, maltodextrin 44.5%; hydrolyzed whey protein 20%; 8% of sunflower seed oil microcapsule powder; 2% of linseed oil microcapsule powder; 8% of medium chain triglyceride microcapsule powder; 5% of fish oil microcapsule powder; 4.5 percent of fructo-oligosaccharide; 4% of mineral premix; 3% of vitamin premix; 1% of probiotic mixed powder.
7. The nutritionally complete formula powder according to claim 1, wherein said vitamin premix consists of the following components:
maltodextrin 31.7% -68.208%; 20% -39% of choline bitartrate; 3% -10% of inositol; 3% -8% of L-carnitine tartrate; 3.5 to 7.5 percent of sodium ascorbate; 1% -4% of taurine; 0.8% -2.8% of vitamin E (50%); 0.1% -0.9% of nicotinamide; 0.1 to 0.6 percent of vitamin A acetate; 0.05 to 0.5 percent of D-calcium pantothenate; vitamin D3(cholecalciferol) 0.05% -0.5%; vitamin B12Cyanocobalamin (0.1% in maltodextrin) 0.05% -0.5%; folic acid (10% maltodextrin) 0.05% -0.5%; 0.05% -0.45% of D-biotin (1% in maltodextrin); vitamin B10.02% -0.45% of thiamine hydrochloride; vitamin B6(pyridoxine hydrochloride) 0.01% -0.45%; vitamin B2(riboflavin) 0.01% -0.45%; vitamin K1(5%) 0.001% -0.35%; potassium iodide (10% in maltodextrin) 0.001% -0.35%.
8. The nutritionally complete formula as in claim 1, whereinThe vitamin premix consists of the following components: 52.7275% of maltodextrin; 25.6078% of choline bitartrate; 6.3333% of inositol; 4.8851% L-carnitine tartrate; sodium ascorbate 4.2442%; taurine 2.0000%; vitamin E (50%) 1.7880%; 0.4563% of nicotinamide; 0.3282% of vitamin A acetate; 0.2802% of D-calcium pantothenate; vitamin D3(cholecalciferol) 0.2400%; vitamin B12Cyanocobalamin (0.1% in maltodextrin) 0.2133%; folic acid (10% maltodextrin) 0.2133%; d-biotin (1% in maltodextrin) 0.1887%; vitamin B1(thiamine hydrochloride) 0.1310%; vitamin B6(pyridoxine hydrochloride) 0.1220%; vitamin B2(riboflavin) 0.1000%; vitamin K1(5%) 0.0800%; 0.0610% potassium iodide (10% in maltodextrin).
9. The nutritionally complete formula according to claim 1, wherein said mineral premix consists of:
15% -22% of monopotassium phosphate; 15% -21% of calcium carbonate; 15% -21% of sodium chloride; 1.2% -35.68% of maltodextrin; 10 to 17 percent of magnesium sulfate (dry product); 9% -15% of potassium citrate-monohydrate; potassium pyrophosphate 0.1% -1%; manganese sulfate-water (10% in maltodextrin) 0.08% -0.45%; 0.06% -0.35% of zinc sulfate monohydrate; sodium selenite (1% in maltodextrin) 0.05% -0.6%; 0.03 to 0.4 percent of copper sulfate.
10. The nutritionally complete formula according to claim 1, wherein said mineral premix consists of:
potassium dihydrogen phosphate 18.7636; 18.6168% of calcium carbonate; 18.4612% of sodium chloride; 16.4669% of maltodextrin; 13.6567% magnesium sulfate (dried product); potassium citrate-12.7481% monohydrate; 0.4800% of potassium pyrophosphate; 0.2467% manganese sulfate-water (10% in maltodextrin); 0.2395% of zinc sulfate monohydrate; 0.1991% sodium selenite (1% in maltodextrin); 0.1212 percent of copper sulfate.
CN202011388124.3A 2020-12-01 2020-12-01 Total nutrient formula powder Pending CN112535283A (en)

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CN113317494A (en) * 2021-06-03 2021-08-31 浙江益元素食品有限公司 Total nutrient formula powder and preparation method and application thereof
CN113397164A (en) * 2021-07-02 2021-09-17 海南天壮营养工程有限公司 Special medical full-nutrition formula food for improving immunity and preparation method thereof
CN113598364A (en) * 2021-08-12 2021-11-05 海南天壮营养工程有限公司 Special medical-use total-nutrient formula food for patients with hematopathy
CN113729211A (en) * 2021-08-04 2021-12-03 北京斯利安健康科技有限公司 Composition and preparation method and application thereof
CN113925170A (en) * 2021-09-26 2022-01-14 南昌大学 Bean-based formula powder with anti-fatigue and immunity-improving functions and preparation method thereof
CN113951411A (en) * 2021-08-31 2022-01-21 国药一心制药有限公司 Formula and preparation process of composite whey protein solid beverage
CN114468063A (en) * 2021-12-28 2022-05-13 上海交通大学医学院 Fatty acid balanced type formula food with special medical application and preparation method thereof
CN115053929A (en) * 2022-05-23 2022-09-16 江西人之初乳品营养有限公司 Formula milk powder suitable for people with fatty liver and preparation method thereof
CN115137063A (en) * 2022-07-14 2022-10-04 浙江益元素营养科技有限公司 Special medical-use total-nutrient formula food for predigested protein and preparation method
CN115137064A (en) * 2022-07-14 2022-10-04 浙江益元素营养科技有限公司 Total nutrient formula food for predigestion special medical application and preparation method
CN115251373A (en) * 2022-08-12 2022-11-01 中科爱伽(天津)医用食品有限公司 Special dietary food for controlling weight, preparation process and application thereof

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Publication number Priority date Publication date Assignee Title
CN113317494A (en) * 2021-06-03 2021-08-31 浙江益元素食品有限公司 Total nutrient formula powder and preparation method and application thereof
CN113397164A (en) * 2021-07-02 2021-09-17 海南天壮营养工程有限公司 Special medical full-nutrition formula food for improving immunity and preparation method thereof
CN113729211A (en) * 2021-08-04 2021-12-03 北京斯利安健康科技有限公司 Composition and preparation method and application thereof
CN113598364A (en) * 2021-08-12 2021-11-05 海南天壮营养工程有限公司 Special medical-use total-nutrient formula food for patients with hematopathy
CN113951411A (en) * 2021-08-31 2022-01-21 国药一心制药有限公司 Formula and preparation process of composite whey protein solid beverage
CN113925170A (en) * 2021-09-26 2022-01-14 南昌大学 Bean-based formula powder with anti-fatigue and immunity-improving functions and preparation method thereof
CN114468063A (en) * 2021-12-28 2022-05-13 上海交通大学医学院 Fatty acid balanced type formula food with special medical application and preparation method thereof
CN115053929A (en) * 2022-05-23 2022-09-16 江西人之初乳品营养有限公司 Formula milk powder suitable for people with fatty liver and preparation method thereof
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CN115137063A (en) * 2022-07-14 2022-10-04 浙江益元素营养科技有限公司 Special medical-use total-nutrient formula food for predigested protein and preparation method
CN115137064A (en) * 2022-07-14 2022-10-04 浙江益元素营养科技有限公司 Total nutrient formula food for predigestion special medical application and preparation method
CN115251373A (en) * 2022-08-12 2022-11-01 中科爱伽(天津)医用食品有限公司 Special dietary food for controlling weight, preparation process and application thereof

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