CN107951015A - Full nutrient formulation powder and preparation method thereof - Google Patents
Full nutrient formulation powder and preparation method thereof Download PDFInfo
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- CN107951015A CN107951015A CN201711469171.9A CN201711469171A CN107951015A CN 107951015 A CN107951015 A CN 107951015A CN 201711469171 A CN201711469171 A CN 201711469171A CN 107951015 A CN107951015 A CN 107951015A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
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Abstract
The present invention relates to a kind of full nutrient formulation powder and preparation method thereof, the full nutrient formulation powder mainly includes following components (total amount is based on 100g)：6~26g of protein, 4~24g of fat, 50~70g of carbohydrate, 2~6g of dietary fiber, 10~30mg of taurine, 180~280mg of vitamin, 1.45~5.45g of inorganic salts；Products characteristics of the present invention are：Carbohydrate is contained with high-content, body energy can be replenished in time rapidly；The dietary fiber content of product of the present invention is high, is conducive to maintain normal function of intestinal canal；Product of the present invention also contains choline bitartrate as one of vitamin, it is easily absorbed and irritation is low, can effectively facilitate the metabolism of fat；Product of the present invention also contains middle chain (C6‑C12) fatty acid triglycercide, energy supply is rapidly.
Description
Technical field
The present invention relates to special medicine purposes formula food field, and in particular to powder whole nutritional prod and its preparation side
Method.
Background technology
Human body is required for absorbing enough heats, protein and multivitamin and mineral matter daily, so as to maintain human body
Normal work function.《Chinese residents dietary guidelines》Point out, breakfast provide energy should account for whole day gross energy 25%~
30%, lunch should account for 30~40%, and dinner should account for 30~40%, and to have breakfast everyday and ensure its nutritional sufficiency, and lunch will
Eat, dinner is appropriate, so reasonably adjusting the intake of breakfast, lunch and dinner nutriment of normal function and body to(for) body
Healthy growth is necessary.In addition, the inpatient, hyperlipemia for middle-aged and elderly people and there are Nutritional Risk need low courage
The patient of sterol diet, perioperatively and for the patient of convalescence, the intake of nutrition is particularly problematic.
Since the degeneration of organ dysfunction and the influence of disease, middle-aged and elderly people's malnutrition incidence are high.Along with the elderly
Underlying diseases increase, a variety of causes cause dysphagia and the disturbance of consciousness, cause to be unable to oral consumption, need the patient of tube feed to get over
Come more or even long-term with pipe existence.Since feed intake reduction etc. causes the supply of appropriate protein or energy not
Foot, causes serious malnutrition, as a result causes the reduction that immunity reduces the infectious disease, muscle strength that trigger occur
Deng.According to foreign statistic, Hospitalized Aged Patients malnutrition is more universal, there are about 30~50%.Therefore, regardless of gerontal patient
How is nutritional status before, should all take in energy, protein and the micronutrient of abundance.
For there are the inpatient of Nutritional Risk, suffer from hyperlipemia and need the patient of low-cholesterol diet, operation consent
Afterwards and for the patient of convalescence, good nutritional support product is to important clinical meaning, it is being corrected metabolic imbalance, is subtracting
The complication such as few infection, the effect of the various treatment means of enhancing, promote rehabilitation, so as to shorten the hospital stays, improve patient's life
Quality etc. has important clinical significance.A Medical economical evaluation once did in the Brazilian Ministry of Public Health, assessment the result is that disease
As soon as people often spends yuan, wholistic therapy expense can reduce by 8 yuans in nutritional support.Meanwhile Abbott Laboratories, hundred spies, Blang, nest etc.
The global clinical trial that several companies carry out jointly also confirms that nutritional support causes the expense of inpatient to drop significantly
It is low.
In nutritional support product, full nutrition formula product is can to meet target group's nutrition need as single source of nutrition
The special medicine purposes formula food asked.However, various natural food powder domestic at present, are not multipotential nutrition element mostly, it is single
Only use cannot fully meet nutritional need；And all-round nutrient powder (homogenate diet), such as 99124658.6 He of Chinese patent application
01114638.9 is various food powders, and level of residue is big, can only use the method injected by several times, easily be returned when dosage is big
Stream, causes the complication such as aspiration pneumonia；In addition, this group food needs access to normally digestion, absorption function, otherwise easily go out
The complication such as existing abdominal distension, diarrhea.Therefore, urgent patient and middle-aged and elderly people, which are used alone, is difficult to reach nutritional need, nutrition condition
It is bad；Negatively correlated between nutritional status and complication, malnutrition can increase the death rate, infection, the generation of pressure ulcer,
Extend the hospital stays.In addition, this kind of patient usually has diabetes, hyperlipidemia, hypertension, renal failure and other diseases, it is desirable to
Appropriate carbohydrate, high-quality protein, compared with low fat, do not take in animal tallow as far as possible.On the other hand, for this two classes patient
Similar import preparation (peace element, Nutrison, good meals, good meals fiber) it is mostly expensive, without dietary fiber, to blood sugar influence
Greatly.
CN103431391A discloses a kind of formula of comprehensive nutrition powder, its raw material is respectively：Vitamin B1, vitamin
B2, vitamin B6, pantothenic acid, nicotinic acid, vitamin B12, vitamin C, vitamin A, vitamin K, vitamin D, vitamin E, biology
Element, folic acid, calcium, magnesium, potassium, iron, zinc, selenium, chromium, copper, manganese.The patent with the addition of multivitamin, can supplement daily required dimension
Raw element, but dietary fiber and unrighted acid are not contained, can not balanced human's full nutrition.
CN106668835A discloses a kind of high protein, higher fatty acid, low-carb Elental, what it was directed to
It is the malnutritive problem of tumor patient, its carbohydrate content is very low, in addition, it is also containing the slower junket egg of absorption
In vain.These features cause it can not be suitable for full nutrient formulation, and can only be used as the non-full nutrient formulation for tumor patient
Food.
It can be seen from the above that the existing nutrition product for patient has the shortcomings that certain, such as various nutrients and trace element
Collocation is not balanced enough, influences patient's nutrient absorption, causes patient malnutritive；Lack dietary fiber effective enough, it is impossible to have
Effect ground adjusts the physiological function of people digest's system, easy constipation；Digestion is slow, enteron aisle bad adaptability, the invasive difference of pre- bacteriological protection,
Cause immunity of organisms not high；Product taste and flavor is bad etc..
The content of the invention
In view of the deficiencies of the prior art, it is an object of the invention to provide a kind of general equilibrium full nutrient formulation powder and its
Preparation method, the full nutrient formulation powder contain carbohydrate with high-content, needed by human body energy can be replenished in time rapidly；This
The dietary fiber content height and wide variety of invention product；Product of the present invention also contain choline bitartrate as vitamin it
One, it is easily absorbed and irritation is low, can effectively facilitate the metabolism of fat；Product of the present invention also contains medium chain fatty acid, energy supply
Rapidly, and trans fats are not included.
To achieve these goals, the present invention uses following technical proposals：
In a first aspect, the present invention relates to a kind of full nutrient formulation powder, counted using the total amount of full nutrient formulation powder as 100g, it is wrapped
Contain：6~26g of protein, 4~24g of fat, 50~70g of carbohydrate, 2~6g of dietary fiber, 10~30mg of taurine, dimension
180~280mg of raw element, 1.45~5.45g of inorganic salts；
Wherein, the protein includes：Soybean protein and lactalbumin；
The fat includes：Canola oil and middle chain (C6-C12) fatty acid triglycercide, but trans fats are free of, and satisfy
Content with fat is the 10%~30% of total fat；
The carbohydrate includes：Maltodextrin and Sucralose, predominantly maltodextrin；
The dietary fiber includes：Resistant dextrin and synanthrin and fructooligosaccharide；
The vitamin includes：Vitamin A and vitamin B1 and vitamin B2 and vitamin B6 and vitamin B12 and Wei Sheng
Plain C and vitamin D and vitamin E and vitamin K and biotin and choline bitartrate and nicotinic acid and folic acid and pantothenic acid；
The inorganic salts include：Calcium pantothenate and calcium carbonate and calcium phosphate and potassium chloride and sodium chloride and magnesia and citric acid
Sodium and potassium citrate and zinc sulfate and ferric pyrophosphate and grape acid manganese and copper sulphate and chromium chloride and sodium selenate and sodium molybdate and iodine
Change potassium.
As one of optimal technical scheme, counted using the total amount of full nutrient formulation powder as 100g, it includes：Protein 11~
21g, 9~19g of fat, 55~65g of carbohydrate, 3~5g of dietary fiber, 15~25mg of taurine, vitamin 205~
255mg, 2.45~4.45g of inorganic salts.
One of preferably, counted using the total amount of full nutrient formulation powder as 100g, it includes：13~23g of protein is (excellent
Elect 15.9g as), 11~17g of fat (be preferably 13.9g), 58~62g of carbohydrate (being preferably 60g), dietary fiber 3.5
~4.5g (being preferably 4.3g), 17~23mg of taurine (being preferably 20mg), 215~245mg of vitamin (preferably 230mg), nothing
Machine salt 2.95~3.95 (being preferably 3.45g).
One of preferably, counted using the total amount of full nutrient formulation powder as 100g, the protein includes：Soybean protein
5~22g (being preferably 13.6g) and 1~4g of lactalbumin (being preferably 2.3g).
One of preferably, counted using the total amount of full nutrient formulation powder as 100g, the fat includes：Canola oil 2.1g
~12.6g (being preferably 7.4g) and 0.5~1.5g of middle chain (C6-C12) fatty acid triglycercide (being preferably 1g), saturated fat
Content is the 21% of total fat.
One of preferably, counted using the total amount of full nutrient formulation powder as 100g, the dietary fiber includes：Resistance is pasted
0.68~2.04g of essence (being preferably 1.5g) and 0.68~2.04g of synanthrin (being preferably 1.5g) and 0.64~1.92g of fructooligosaccharide are (excellent
Elect 1.3g as).
One of preferably, counted using the total amount of full nutrient formulation powder as 100g, the vitamin includes：Vitamin A
0.1~1mg (being preferably 0.46mg) and 0.5~1.5mg of vitamin B1 (being preferably 0.9mg) and 0.5~1.5mg of vitamin B2
(being preferably 0.9mg) and 0.5~1.5mg of vitamin B6 (being preferably 1.1mg) and vitamin B12 are 1~2 μ g (preferably 1.4 μ
And 42.5~82.5mg of vitamin C (be preferably 62.5mg) and 1~10 μ g of vitamin D (preferably 5 μ g) and vitamin E 3 g)
~13mg (being preferably 8mg) and 28~48 μ g of vitamin K (being preferably 38 μ g) and 8~28 μ g of biotin (being preferably 17.9 μ g)
With 100~200mg of choline bitartrate (being preferably 143mg) and 3~13mg of nicotinic acid (being preferably 8.2mg) and folic acid 100~150
μ g (being preferably 134 μ g) and 2~6mg of pantothenic acid (being preferably 4.3mg).
One of preferably, counted using the total amount of full nutrient formulation powder as 100g, the inorganic salts include：Calcium pantothenate
0.001~0.01g (being preferably 0.0055g) and 0.5~1.5g of calcium carbonate (being preferably 0.95g) and 0.1~0.5g of calcium phosphate are (excellent
Elect 0.3g as) and 0.5~1.5g of potassium chloride (being preferably 1g) and 0.01~0.1g of sodium chloride (being preferably 0.06g) and magnesia
0.1~0.2g (be preferably 0.15g) and 0.2~1.2g of sodium citrate (preferably 0.7g) and 0.1~0.4g of potassium citrate is (preferably
For 0.25g) and 0.01~0.02g of zinc sulfate (being preferably 0.013g) and 0.01~0.02g of ferric pyrophosphate (being preferably 0.014g)
With 0.01~0.03g of grape acid manganese (be preferably 0.02g) and 0.5~1.5mg of copper sulphate (preferably 1mg) and chromium chloride 0.05~
0.15mg (being preferably 0.1mg) and 20~100 μ g of sodium selenate (being preferably 60 μ g) and 0.05~0.15mg of sodium molybdate (are preferably
0.12mg) and 0.05~0.15mg of potassium iodide (be preferably 0.1mg),
Preferably, the full nutrient formulation powder also includes flavouring, its one kind in natural perfume material and artificial flavors
Or two kinds.
Second aspect, the present invention provide a kind of preparation method of full nutrient formulation powder, it comprises the following steps：
(1) weigh：All raw material auxiliary materials are weighed；
(2) premix：First each vitamin, each inorganic salts, Sucralose, taurine are premixed, premix about 20~30min
(preferably 25min), until uniformly；
(3) sieve：By canola oil powder, middle chain (C6-C12) fatty acid triglycercide powder, maltodextrin, lactalbumin, soybean
Respective 10 mesh sieve of mistake of the premix obtained in albumen, resistant dextrin, synanthrin, fructooligosaccharide, spices and above-mentioned steps (2), sieving
Condition is not more than 28 DEG C for temperature and humidity is not more than 65%；
(4) it is total mixed：By canola oil powder, middle chain (C6-C12) fatty acid triglycercide powder, maltodextrin, lactalbumin, soybean
Albumen, resistant dextrin, synanthrin, fructooligosaccharide and spices are added into above-mentioned steps (2) in obtained premix, and mixing 20~
40min (preferably 30min), until uniformly, the condition of mixing is no more than 28 DEG C and humidity is not more than 65%；
(5) fill, pack：Obtained total mixed powder is filled with the specification needed canned.
[effect of the invention]
In full nutrient formulation powder of the present invention, the various nutrients comprising needed by human body, i.e. protein, lipid, carbon water
Compound, vitamin, inorganic salts and dietary fiber.Carbohydrate is contained with high-content, needed by human body can be replenished in time rapidly
Energy.
The dietary fiber content of product of the present invention is high and dietary fiber wide variety, comprising resistant maltodextrin, fructooligosaccharide,
Synanthrin, can effectively facilitate digestion, adjust blood glucose and reduce the absorption in digestion process to fat.
Product of the present invention also contains choline bitartrate as one of vitamin, it is easily absorbed and irritation is low, Neng Gouyou
Effect promotes the metabolism of fat.In addition, diversified needed by human body vitamin is also included, such as vitamin A and vitamin B1 and dimension
Raw element B2 and vitamin B6 and vitamin B12 and vitamin C and vitamin D and vitamin E and vitamin K and biotin and nicotinic acid
With folic acid and pantothenic acid.
Product of the present invention also contains medium chain fatty acid, and energy supply is rapid, and does not include trans fats.
Protein 100% in product of the present invention derives from good protein, include animal protein (lactalbumin) and
Vegetable protein (soybean protein), wherein rich in arginine and branched-chain amino acid, helps to increase protein synthesis, prevention decomposition generation
Thank, promote the reparation of cell and tissue, be conducive to strengthen immunity of organisms, reduce postoperative infection risk.
Taurine is included in product of the present invention.Taurine is the indispensable amino acid of human body, has and maintains normal vision
Function, maintain osmotic balance, maintain cell film temperature, hypoglycemic, protective tissue ischemical reperfusion injury, improve immunity of organism
Power, adjust the extensive biological actions such as lipid secretion, protection cardiac muscle cell.In addition, taurine additionally aids help cell membrane
Formed and cholic acid carries out fat emulsification.
Also it can improve mouthfeel comprising flavouring such as spices in product of the present invention.
Simple production process of the present invention, raw material sources are extensive, easy to carry, eat simplicity；And it is widely used, it can be used as auxiliary
Food, can also eat as single source of nutrition.
It can be seen from the above that the full nutrient formulation powder of the present invention is capable of providing safe various nutrition that are balanced, meeting physiological requirements
Element and trace element, can improve patient's entirety nutrition condition, and hepatic and renal function is not damaged.
Embodiment
The present invention is further described in detail with reference to embodiment, the embodiment provided is only for explaining
The bright present invention, the scope being not intended to be limiting of the invention.
Embodiment 1：The preparation of full nutrient formulation powder of the invention
1st, composition of raw materials is as shown in table 1：
Table 1：The preparing raw material of full nutrient formulation powder of the present invention
2nd, preparation method
(1) weigh：All raw material auxiliary materials are weighed；
(2) premix：First each vitamin, each inorganic salts, Sucralose, taurine are premixed, premix about 25min, directly
To uniform；
(3) sieve：By canola oil powder, middle chain (C6-C12) fatty acid triglycercide powder, maltodextrin, lactalbumin, soybean
Respective 10 mesh sieve of mistake of the premix obtained in albumen, resistant dextrin, synanthrin, fructooligosaccharide, spices and above-mentioned steps (2), sieving
Condition is not more than 28 DEG C for temperature and humidity is not more than 65%；
(4) it is total mixed：By canola oil powder, middle chain (C6-C12) fatty acid triglycercide powder, maltodextrin, lactalbumin, soybean
Albumen, resistant dextrin, synanthrin, fructooligosaccharide and spices are added into above-mentioned steps (2) in obtained premix, mix 30min, directly
To uniform, the condition of mixing is no more than 28 DEG C and humidity is not more than 65%；
(5) fill, pack：Obtained total mixed powder is filled with the specification needed canned.
The testing result such as table 2 for the full nutrient formulation powder that the present embodiment is prepared：
Table 2：Nutritional agents testing result of the present invention
Embodiment 2：The preparation of full nutrient formulation powder of the invention
1st, composition of raw materials is as shown in table 3：
Table 3：The preparing raw material of full nutrient formulation powder of the present invention
2nd, preparation method
(1) weigh：All raw material auxiliary materials are weighed；
(2) premix：First each vitamin, each inorganic salts, Sucralose, taurine are premixed, premix about 25min, directly
To uniform；
(3) sieve：By canola oil powder, middle chain (C6-C12) fatty acid triglycercide powder, maltodextrin, lactalbumin, soybean
Respective 10 mesh sieve of mistake of the premix obtained in albumen, resistant dextrin, synanthrin, fructooligosaccharide, spices and above-mentioned steps (2), sieving
Condition is not more than 28 DEG C for temperature and humidity is not more than 65%；
(4) it is total mixed：By canola oil powder, middle chain (C6-C12) fatty acid triglycercide powder, maltodextrin, lactalbumin, soybean
Albumen, resistant dextrin, synanthrin, fructooligosaccharide and spices are added into above-mentioned steps (2) in obtained premix, mix 30min, directly
To uniform, the condition of mixing is no more than 28 DEG C and humidity is not more than 65%；
(5) fill, pack：Obtained total mixed powder is filled with the specification needed canned.
The testing result such as table 4 for the full nutrient formulation powder that the present embodiment is prepared：
Table 4：Nutritional agents testing result of the present invention
Effect assessment
1st, nutritive index is evaluated
By taking the full nutrient formulation powder that Examples 1 and 2 obtain as an example, by its with《National food safety standard special medicine is used
Way formula food general rule》Indices as defined in GB 29922-2013 compare one by one, and discovery meets the requirements.
2nd, the glycemic index experiment of full nutrient formulation powder of the invention
(1) research object
Volunteer is recruited, by volunteer's readme without the disease in terms of intestines and stomach, food hypersenstivity, metabolism or other health
Problem person, and help with oral glucose tolerance test (Oral Glucose Tolerance Test, OGTT) to test subject
Make screening conditions for the sensitiveness of blood glucose, research object is used as by the euglycemia reactor after screening.Subject age
About between 18~25 years old, during experiment, subjects, which are not taken, any can influence change of blood sugar or hormone secretion
Medicine.
Totally 25 subjects, subject's basic document are as follows
(2) test material
Standard food using glucose solution as experiment, trial target：The full nutrient formulation powder of the embodiment of the present invention 1.
(3) test procedure
Code test food：The subject 1 part trial target of 200 milliliters of glucose solutions containing 25g is given, and after edible
0th, 30,60,90,120min when carry out capilary blood-sample withdrawal with blood glucose machine testing blood glucose value, fixation is same from subject every time
The finger tip of side hand adopts capilary blood sample to detect blood glucose.
Trial target：Give 1 part of subject containing 25g can by the use of the full nutrient formulation powder of the invention of carbohydrate as trial target,
And capilary blood-sample withdrawal is carried out with blood glucose machine testing blood glucose value when the edible rear 0th, 30,60,90,120min, it is fixed every time
Capilary blood sample is adopted from the finger tip of subject the same side hand to detect blood glucose.
(4) parameter declaration and processing
(a) glycemic index：Measure code test food and trial target (full nutrient formulation powder of the invention) each time point
Blood sugar concentration and change, run a curve.Its GI value calculates Portugal as 100 during using glucose solution as code test food
Grape sugar and trial target area under the curve, obtain ratio × 100.
The tested food blood sugar areas of GI=/refer to food blood sugar area × 100
After each product G I values measured by above-mentioned formula calculates subject, then the numerical value of all subjects is obtained into arithmetic and is put down
Average.
(b) glycemic load
The amount (g) of the GI values (%) of the food × food institute carbohydrate containing
(5) statistical analysis
Using statistical software SAS for Windows 9.01 editions, analyzed, used using paired t-test
Scheffe carries out after-only measurement, when p ＜ 0.05 have statistical difference.
(6) result of the test
Subject is after fasting blood-glucose is measured, intake code test food-glucose solution containing 25g, the 30th, 60,
90th, the average blood sugar value (mg/dL) of 120 minutes, which changes, is respectively：147.2±16.9、112.9±21.0、86.9±19.4、
87.9±9.7mg/dL；Area under the curve of blood glucose is 2474.4 ± 665.8.During using glucose solution as code test food
Its GI value is 100.
After subject's ingestion experiment food (full nutrient formulation powder of the invention), in the 30th, 60,90,120 minute be averaged
Blood glucose value (mg/dL) changes：130.7±13.7、105.2±13.2、92.8±8.8、90.4±8.0mg/dL；Blood glucose
Area under the curve is 1688.8 ± 415.1.GI values after being compared through the standard items with glucose solution are 70.8.It is glycemic negative
Charge values are 17.7, and the glycemic equivalent of glucose is 41.2, more excellent.
3rd, the clinical test of full nutrient formulation powder of the invention
(1) research object
By swan-neck fill in a manner of diet and continue more than 3 months pipe filling diet patient for subjects.Pipe fills drink trencherman
Condition standard：More than 20 years old, male or female, long-time service enteral feeding tube patient.Totally 58, including 37 males and 21 women,
Intervention group and control group are respectively enterd after numbering.
(2) experiment process
This research is designed using time series study.Diet method of supplying assesses every subject's energy by nutritionist
Requirement is measured, at least awards every 1500~1800 kilocalories of subject 1 day, wherein protein accounts for percent of calories 16.2%, fat
Fat 32.4%, carbohydrate 51.4%.Supply mode gives the 56.2g full nutrient formulation powder of the present invention for often meal, eats within 1 day 6.
Test period：3 months (including 1 month observation period, 1 month intervention phase, 1 month the tracking phase).Do not change former fill during intervention to eat
Speed.
Before experiment starts, personal basic document is recorded, including：Age, gender, history of disease, bed year.Measure its liter
High, weight, calculates body-mass index, measurement blood pressure and collects blood, carry out biochemical values inspection.
Observation period does not change edible pipe originally and fills formula.By researcher record subject's diet regimen amount, digestion situation,
Defecation situation.The intervention phase gives subject's full nutrient formulation powder of the present invention, records subject's diet regimen amount, digestion feelings afterwards
Condition, defecation situation (diarrhea or abdominal distension situation whether occur).Subject's full nutrient formulation powder of the present invention is given in the stopping of tracking phase
And reply former edible formula, record subject's nutriment dose, defecation situation.
(3) biochemical investigation
Extract subject's venous blood before the meal, after 3000rpm, 10min centrifugation, isolate serum, blood plasma, carry out blood cell with
Biochemistry etc. measures, and blood test commission professional inspection is carried out.
Biochemical analysis includes：Blood lipid index (cholesterol, triglyceride), renal function index (blood urea nitrogen (BUN), flesh
Acid anhydrides), (glutamic-oxalacetic transaminease, glutamic-pyruvic transaminase, paddy ammonia phenol transferase, total bilirubin, lactic acid take off liver function index
Hydrogen enzyme), nutritional status index (total protein, albumin) and other.
(4) statistical analysis
Using statistical analysis software SAS for Windows 9.01 editions, unprired t-test, one-way are utilized
ANOVA, chi-square test are analyzed, and after-only measurement are carried out using Scheffe, when p ＜ 0.05 have statistical difference
It is different.
(5) result
Jie enrolled subject gives the albumin concentration of the full nutrient formulation powder of the present invention of 1 month before, during and after intervention
For 3.6 ± 0.5g/dL, but without significant difference.Blood lipid index：T-CHOL has downward trend, its concentration by 169.94 ±
43.1mg/dL drops to 165.4 ± 44.0mg/dL, but does not have notable meaning；TG has downward trend, its concentration by 135.1 ±
74.5mg/dL drops to 114.8 ± 49.5mg/dL, but does not have notable meaning；Liver function index：GPT is on the rise, its is dense
Degree rises to 21.3 ± 9.6mg/dL by 19.2 ± 4.8mg/dL, but does not have notable meaning；GOT concentration is by 29.4 ± 7.4mg/dL
26.8 ± 7.0mg/dL is dropped to, but does not have notable meaning；Renal function：BUN concentration rises to 13.0 by 12.84 ± 3.1mg/dL
± 5.3mg/dL, but do not have notable meaning.Serum creatinine concentration maintains 0.7 ± 0.3mg/dL；Its remainder values such as r-GT,
The average values such as TB, LDH, UA, CPK are in normal range (NR).
From above-mentioned two experimental result, full nutrient formulation powder of the invention is balanced nutritious formula, with the present invention's
Full nutrient formulation powder substitutes original pipe to fill diet, and it is balanced nutritious to give patient, can maintain patient's nutritional status, and liver function
Energy, renal function are without corruptions.
In addition volunteer gives an oral account the full nutrient formulation powder good mouthfeel of the present invention.The full nutrient medium of the present invention achieves
Excellent technique effect.
4th, with the comparisons of other full nutrient formulation powder
In order to illustrate more clearly of the present invention full nutrient formulation powder excellent effect, applicant also with other cities of this area
Product (being named as commercial product 1 and 2 below) is sold to compare, it is as a result as shown in the table.
As seen from the above table, the present invention can obtain more excellent technique effect in terms of parameters.
Specific description of embodiments of the present invention above is not intended to limit the present invention, and those skilled in the art can be according to this
Invention is variously modified or deforms, and without departing from the spirit of the present invention, should all belong to the models of appended claims of the present invention
Enclose.
Claims (9)
1. a kind of full nutrient formulation powder, is counted using the total amount of full nutrient formulation powder as 100g, it includes：6~26g of protein, fat 4
~24g, 50~70g of carbohydrate, 2~6g of dietary fiber, 10~30mg of taurine, 180~280mg of vitamin, inorganic salts
1.45~5.45g；
Wherein, the protein includes：Soybean protein and lactalbumin；
The fat includes：Canola oil and middle chain (C6-C12) fatty acid triglycercide, but trans fats are free of, and saturated fat
The content of fat is the 10%~30% of total fat；
The carbohydrate includes：Maltodextrin and Sucralose, predominantly maltodextrin；
The dietary fiber includes：Resistant dextrin and synanthrin and fructooligosaccharide；
The vitamin includes：Vitamin A and vitamin B1 and vitamin B2 and vitamin B6 and vitamin B12 and vitamin C
With vitamin D and vitamin E and vitamin K and biotin and choline bitartrate and nicotinic acid and folic acid and pantothenic acid；
The inorganic salts include：Calcium pantothenate and calcium carbonate and calcium phosphate and potassium chloride and sodium chloride and magnesia and sodium citrate and
Potassium citrate and zinc sulfate and ferric pyrophosphate and grape acid manganese and copper sulphate and chromium chloride and sodium selenate and sodium molybdate and potassium iodide.
2. full nutrient formulation powder as claimed in claim 1, is counted using the total amount of full nutrient formulation powder as 100g, it includes：Albumen
11~21g of matter, 9~19g of fat, 55~65g of carbohydrate, 3~5g of dietary fiber, 15~25mg of taurine, vitamin 205
~255mg, 2.45~4.45g of inorganic salts.
3. full nutrient formulation powder as claimed in claim 1 or 2, is counted using the total amount of full nutrient formulation powder as 100g, it includes：Egg
13~23g of white matter (being preferably 15.9g), 11~17g of fat (being preferably 13.9g), 58~62g of carbohydrate (are preferably
60g), 3.5~4.5g of dietary fiber (be preferably 4.3g), 17~23mg of taurine (being preferably 20mg), vitamin 215~
245mg (preferably 230mg), inorganic salts 2.95~3.95 (being preferably 3.45g).
4. such as full nutrient formulation powder according to any one of claims 1 to 3, counted using the total amount of full nutrient formulation powder as 100g,
The protein includes：5~22g of soybean protein (being preferably 13.6g) and 1~4g of lactalbumin (being preferably 2.3g).
5. such as full nutrient formulation powder according to any one of claims 1 to 4, counted using the total amount of full nutrient formulation powder as 100g,
The fat includes：Canola oil 2.1g~12.6g (being preferably 7.4g) and middle chain (C6-C12) fatty acid triglycercide 0.5~
1.5g (being preferably 1g), the content of saturated fat is the 21% of total fat.
6. such as full nutrient formulation powder according to any one of claims 1 to 5, counted using the total amount of full nutrient formulation powder as 100g,
The dietary fiber includes：0.68~2.04g of resistant dextrin (being preferably 1.5g) and 0.68~2.04g of synanthrin (being preferably 1.5g)
With 0.64~1.92g of fructooligosaccharide (being preferably 1.3g).
7. such as full nutrient formulation powder according to any one of claims 1 to 6, counted using the total amount of full nutrient formulation powder as 100g,
The vitamin includes：0.1~1mg of vitamin A (being preferably 0.46mg) and 0.5~1.5mg of vitamin B1 (are preferably
0.9mg) and 0.5~1.5mg of vitamin B2 (be preferably 0.9mg) and 0.5~1.5mg of vitamin B6 (preferably 1.1mg) and
Vitamin B12 is 1~2 μ g (being preferably 1.4 μ g) and 42.5~82.5mg of vitamin C (being preferably 62.5mg) and vitamin D 1
~10 μ g (be preferably 5 μ g) and 3~13mg of vitamin E (being preferably 8mg) and 28~48 μ g of vitamin K (preferably 38 μ g) and
8~28 μ g of biotin (being preferably 17.9 μ g) and 100~200mg of choline bitartrate (being preferably 143mg) and 3~13mg of nicotinic acid
(being preferably 8.2mg) and 100~150 μ g of folic acid (being preferably 134 μ g) and 2~6mg of pantothenic acid (being preferably 4.3mg).
8. such as full nutrient formulation powder according to any one of claims 1 to 7, counted using the total amount of full nutrient formulation powder as 100g,
The inorganic salts include：0.001~0.01g of calcium pantothenate (being preferably 0.0055g) and 0.5~1.5g of calcium carbonate (are preferably
0.95g) and 0.1~0.5g of calcium phosphate (be preferably 0.3g) and 0.5~1.5g of potassium chloride (preferably 1g) and sodium chloride 0.01~
0.1g (being preferably 0.06g) and 0.1~0.2g of magnesia (being preferably 0.15g) and 0.2~1.2g of sodium citrate (are preferably
0.7g) and 0.1~0.4g of potassium citrate (be preferably 0.25g) and 0.01~0.02g of zinc sulfate (being preferably 0.013g) and Jiao's phosphorus
Sour 0.01~0.02g of iron (being preferably 0.014g) and 0.01~0.03g of grape acid manganese (preferably 0.02g) and copper sulphate 0.5~
1.5mg (being preferably 1mg) and 0.05~0.15mg of chromium chloride (being preferably 0.1mg) and 20~100 μ g of sodium selenate (is preferably 60 μ
G) and 0.05~0.15mg of sodium molybdate (be preferably 0.12mg) and 0.05~0.15mg of potassium iodide (preferably 0.1mg),
Preferably, the full nutrient formulation powder also includes flavouring, its one kind or two in natural perfume material and artificial flavors
Kind.
9. the preparation method of full nutrient formulation powder according to any one of claims 1 to 8, it comprises the following steps：
(1) weigh：All raw material auxiliary materials are weighed；
(2) premix：First each vitamin, each inorganic salts, Sucralose, taurine are premixed, premix about 20~30min is (excellent
Select 25min), until uniformly；
(3) sieve：By canola oil powder, middle chain (C6-C12) fatty acid triglycercide powder, maltodextrin, lactalbumin, soybean egg
In vain, respective 10 mesh sieve of mistake of the premix obtained in resistant dextrin, synanthrin, fructooligosaccharide, spices and above-mentioned steps (2), the bar of sieving
Part is not more than 28 DEG C for temperature and humidity is not more than 65%；
(4) it is total mixed：By canola oil powder, middle chain (C6-C12) fatty acid triglycercide powder, maltodextrin, lactalbumin, soybean egg
In vain, resistant dextrin, synanthrin, fructooligosaccharide and spices are added into above-mentioned steps (2) in obtained premix, mix 20~40min
(preferably 30min), until uniformly, the condition of mixing is no more than 28 DEG C and humidity is not more than 65%；
(5) fill, pack：Obtained total mixed powder is filled with the specification needed canned.
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| CN108741086A (en) * | 2018-06-07 | 2018-11-06 | 山东理工大学 | A kind of sports tonica and preparation method thereof suitable for long-term body-building |
| CN108741029A (en) * | 2018-05-28 | 2018-11-06 | 广州正广生物科技有限公司 | High fat diet nutrient powder and preparation method thereof |
| CN108783459A (en) * | 2018-07-03 | 2018-11-13 | 麦孚营养科技（北京）有限公司 | The low slag nutrient formulation product of pea protein, Its Preparation Method And Use |
| CN108936602A (en) * | 2018-06-07 | 2018-12-07 | 山东理工大学 | A kind of double protein sports tonica and preparation method thereof |
| CZ308121B6 (en) * | 2018-05-25 | 2020-01-15 | Euro Enterprise Development s.r.o. | Nutritional composition |
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| CZ308121B6 (en) * | 2018-05-25 | 2020-01-15 | Euro Enterprise Development s.r.o. | Nutritional composition |
| CN108741029A (en) * | 2018-05-28 | 2018-11-06 | 广州正广生物科技有限公司 | High fat diet nutrient powder and preparation method thereof |
| CN108741029B (en) * | 2018-05-28 | 2021-11-09 | 广州正广生物科技有限公司 | Ketogenic dietary nutrition powder and preparation method thereof |
| CN108741086A (en) * | 2018-06-07 | 2018-11-06 | 山东理工大学 | A kind of sports tonica and preparation method thereof suitable for long-term body-building |
| CN108936602A (en) * | 2018-06-07 | 2018-12-07 | 山东理工大学 | A kind of double protein sports tonica and preparation method thereof |
| CN108783459A (en) * | 2018-07-03 | 2018-11-13 | 麦孚营养科技（北京）有限公司 | The low slag nutrient formulation product of pea protein, Its Preparation Method And Use |
| CN110810845A (en) * | 2019-12-03 | 2020-02-21 | 复旦大学附属金山医院 | Total nutrient formula powder with ketogenesis, fat reduction and sugar resistance functions and application thereof |
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| CN116210889A (en) * | 2023-03-22 | 2023-06-06 | 中国农业科学院特产研究所 | Total nutrient formula food and application thereof |
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