CN103284039A - Weight-reducing composition and preparation method thereof - Google Patents
Weight-reducing composition and preparation method thereof Download PDFInfo
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Abstract
The invention provides a weight-reducing composition and a preparation method thereof. The weight-reducing composition comprises the following components by mass percent: 5-80% of resistant dextrin, 0.5-20% of L-arabinose, 1-50% of polydextrose, 0.1-10% of L-carnitine, 0-5% of konjac flour, 0-10% of fruit powder, 0-10% of tea powder, 0-45% of concentrated apple juice, 0-0.5% of composite B vitamins, 0-0.4% of taurine, 0-2% of acidity regulator, 0-0.4% of fruity flavor, and 0-1% of sweetening agent. The weight-reducing composition has the beneficial effects of being good in curative effect, small in side effect, good in flavor and convenient to use.
Description
Technical field
The present invention relates to health products, field of functional food, particularly a kind of Weight reducing compound and preparation method thereof.
Background technology
Obesity refers to that obvious overweight and fat deposit to a certain degree is blocked up, is body fat, and especially triglycerides gathers a kind of state that too much causes.Owing to food intake too much or the change of organism metabolism cause body fat to gather too much causing excess weight to increase and cause human pathology, physiological change or hide.Along with the raising of people's living standard, obesity is more and more sees, and each age group all has.Medicine and the method for the treatment of of obesity at present are more, but have obvious curative effects and have no side effect, raciness, seldom easy to use.
So need a new Weight reducing compound of research and development to solve this defective.
Summary of the invention
The present invention proposes a kind of Weight reducing compound and preparation method thereof, has solved that weak curative effect in the prior art, side effect are big, the defective of weak flavor, use inconvenience.
Technical scheme of the present invention is achieved in that
A kind of Weight reducing compound and preparation method thereof is characterized in that, comprises following component by mass percent: resistant dextrin 5-80%; L-arabinose 0.5-20%, polydextrose 1-50%, l-cn 0.1-10%; konjaku flour 0-5%; Fruit powder 0-10%, tea powder 0-10%, concentrated apple juice 0-45%; taurine 0-0.4%; composite B vitamin 0-0.5%, acidity regulator 0-2%, fruity flavor 0-0.4%, sweetener 0-1%.
Further, described Fruit powder comprises more than one the Fruit powder in lemon powder, strawberry powder, guava powder or the orange powder.
Further, described tea powder comprises any tea powder in green tea, black tea, oolong tea, white tea or the black tea.
Further, described composite B vitamin comprises the two or more B family vitamins in vitamin B1, vitamin B2, vitamin B6, cobalamin, nicotinic acid, pantothenic acid or the folic acid.
Further, described acidity regulator comprises more than one conditioning agents of citric acid, lactic acid, tartaric acid, malic acid, natrium citricum or potassium citrate.
Further, described sweetener comprises more than one sweet taste conditioning agents in Sucralose, Aspartame, stevioside, acesulfame potassium, xylitol or the isomalt.
Further, the preparation process of described Weight reducing compound granule is as follows:
Take by weighing required raw material, sieve, mix, granulate, oven dry is in the aluminium foil bag of packing at last.
Further, the preparation process of described Weight reducing compound beverage is as follows:
Take by weighing required material, heating for dissolving, constant volume, can is sealed, and autoclaving is namely.
Described Weight reducing compound includes but not limited to following: tablet, capsule, oral liquid, granule, pill.
The L-arabinose, English name L-Arabinose, L (+)-pectinose that is otherwise known as, L (+)-arabinose, arabinose etc. extensively are present in the plant, usually be combined with other monose, be present in colloid, hemicellulose, pectic acid, bacterial polysaccharides and some glucosides with the form of heteroglycan.The conventional use of L-arabinose is sweetener.In recent years, scientist and nutritionist are by discovering in a large number, the L-arabinose can optionally suppress the activity of the invertase of digestion sucrose in the small intestine, thereby suppress the absorption of sucrose, therefore the L-arabinose has had application widely at aspects such as fat-reducing, control diabetes, as dieletic foodstuff, diet food, fat-reducing medicine etc.
Resistant dextrin is processed by starch, is will bake the indigestibility composition of dextrin with a kind of Low Caloric Polydextrose that the industrial technology extraction is handled and refining forms, and belongs to low macromolecule water-solubility dietary fiber.Resistant dextrin is managed as bread and cheese by Ministry of Public Health's approval, as a kind of solubility raw-food material low in calories, the vast potential for future development that has in food industry.Resistant dextrin has following physiological action: (1) is providing the effect in heat and the nutrition to be equal to dietary fiber, resistant dextrin is different from standard starch and as resistant starch, in fact partly be hydrolyzed on gastral top: only 15% in small intestine by enzymic digestion, and remainder enters large intestine, 75% of primary quantity is fermented in large intestine at leisure gradually, and 10% excretes.(2) control blood sugar effect is taken in resistant dextrin and can be caused hypoglycemia and blood insulin reaction, and therefore as the carbohydrate that slowly releases energy, it can partially or completely replace other carbohydrate, for example sugar and starch.(3) control volume recast usefulness, resistant dextrin also helps to postpone the generation again of hunger except increasing the content of fiber in the food simply, and this observation and summary with the influence of the satisfaction of the high food of fiber content and feed back satiety is consistent.(4) enteron aisle prebiotic function, resistant dextrin are to show beneficial bacteria of intestinal tract by colon fermentation to increase, and harmful bacterium reduces the reduction of enteron aisle pH value.
L-cn claims the L-carnitine again, is a kind of amino acid that impels fat to be converted into energy, and red meat is the main source of l-cn, and human body is had no side effect.The major physiological function of l-cn is to promote that fat changes into energy, taking l-cn can be when reducing body fat, reducing body weight, do not reduce moisture and muscle, regarded as the safest fat-reducing nutrient complementary goods that has no side effect in 2003 by international fat health tissues.L-cn is a kind of essential coenzyme in the fat metabolism process, can promote aliphatic acid to enter mitochondria and carry out oxidation Decomposition.L-cn has really reached the health slimming three big standards of The World Health Organization's defined in the fat-reducing process: not apocleisis, do not suffer from diarrhoea, not weak.
Polydextrose can be regulated lipid metabolism, polydextrose can cause a skim in small intestine, and swathe the part food fat, can effectively limit the absorption of fat in the alimentary canal, promote the drainage of lipids, increase satiety, reduce food-intake, thereby reach the adjusting blood fat, reduce fat accumulation, effects such as prevention of obesity.
Konjaku flour can form a kind of protective layer around the food, thereby prevents that digestive ferment and food from having an effect; Can appetite-suppressing, produce satiety, food-intake is descended; Can delay, stop cholesterol, the absorption of nutriments such as monose, thus make fat and acid synthetic minimizing in vivo; Ease constipation, the function of defaecation can increase feces volume, therefore has the effect that enteron aisle cleans.
Experiment one
1 animal used as test
Healthy male SD rat, body weight is 100g ± 5g.
2 materials
2.1 reagent
Wonderful appearance fat-reducing poison expelling capsule, blood sugar detection kit are analyzed pure.
2.2 instrument
Automatic clinical chemistry analyzer, low speed centrifuge, balance.
2.3 high-sugar-fat-diet
The high glucose and high fat feed formula is: rat basal feed 60%, lard 10%, dry ferment 10%, yolk powder 10%, sucrose 9%, salt 1%.
3 experimental techniques
3.1 the animal grouping is set up with model
Choose 60 healthy SD rats, animal adaptability is raised a week.Rat is divided into 10 of normal group at random, gives normal diet and feed; 50 of fat modeling groups give the high glucose and high fat forage feed.Two groups of free diet drinking-water of rat are fed 45d.Behind the 45d, filter out 40 body weight and surpass the healthy rat of normal control group average weight more than 20%, be the fat model group rat of success, be divided into four groups at random by body weight: model group, experiment contrast group, experiment low dose group, experiment high dose group.
3.2 weight intervention
After the modeling success, gastric infusion once a day, the perfusion amount is the 10mL/kg body weight.Normal group and model group gavage equal-volume distilled water.The experiment contrast group is irritated wonderful appearance fat-reducing poison expelling capsule 4mg/kg(with dissolved in distilled water every day) body weight, experiment low dose group and high dose group gavage by 5mL/kg, 10mL/kg respectively with the drink agent that the present invention prepares every day.Successive administration 60d.During the administration, normal group continues to feed with normal diet, and fat model group, medicine group, experiment low dose group and experiment high dose group continue to feed with the high glucose and high fat beverage.
3.3 method of testing
3.3.1 fat-reducing, lipopenicillinase dynamic observe
Weighed once in per 15 days, and note variations such as animal behavior, diet and figure.After the last administration, measure its body length, tail length and chest measurement.
3.3.2 index determining
3.3.2.1Lee's index calculates: fasting 24h after the administration of last feeding, the disconnected cervical vertebra of rat is put to death, weigh in, rat to be divided lain on the back, the length of accurately measuring from the rat nose to anus with tape measure is long as body, according to formula
Calculate the Lee's index.
3.3.2.2 the blood sugar biochemical indicator is measured
The rat of having put to death is peeled off arteria carotis communis, blood sample collection, every part of 3mL, place test tube, centrifugal and separation of serum, detect its serum total cholesterol (TC) with enzyme process, triglycerides (TG), HDL-C (HDL-cl) and LDL-C (LDL-ch) by the kit explanation.
3.3.2.3 blood sugar detection
Adopt blood sugar detection kit measurement blood-sugar content: adopt blood taking needle to puncture palpebra interna, get blood 50 μ l, with 5 times of physiological saline dilutions, the centrifugal 10min of 4000r/mim, separation of serum is measured rat fasting blood-glucose (FBG), the mmol/L of unit with Reagent kit of glucose.
3.2.4 the abdominal cavity fat weight in wet base is measured
Cut the rat of having put to death open abdominal cavity, separate rat perirenal fat pad and epididymal adipose tissues pad, place on the filter paper, inhale and remove tissue fluid, with electronic balance weighing weight in wet base and record.Fat index=fat weight (g)/100g body weight.
4 experimental results
During the weight-reducing experiment, experimental group rat behavior, diet are normal, and mental status is good, but model group rat figure tubbiness, and blank group, experimental group, the figure is more elongated for the experiment contrast group.Feed when finishing, extremely locate rat, dissect and observe all normal, no pathologies such as liver, heart, kidney.
4.1 weight-reducing drinks are to the influence (seeing Table 1) of the weight of animals
Table 1 weight-reducing drinks are to the influence of obese rat body weight
Can obtain conclusion from above data: experiment high dose group, low dose group and model group contrast, body weight all obviously reduces, all difference remarkable (P＜0.05 or P＜0.01).Compare with model group, the low dose group rat body weight is light by 32.7%, the high dose group rat body weight is light by 46.7%, fat-reducing effect is remarkable, and high dose group and experiment contrast group rat body weight no significant difference, the drink agent of provable the present invention preparation all has the effect of obvious control body weight for alimentary obesity type rat, and alternative toxin expelling slimming medicine is used for the fat-reducing toxin expelling.
4.2 weight-reducing drinks are to the influence (seeing Table 2) of rat blood sugar index
Table 2 weight-reducing drinks are to the influence (unit: mmol/L) of obese rat blood sugar
Annotate: blood glucose value before the blood sugar rate of descent %=(experiment-experiment back blood glucose value)/blood glucose value * 100% before testing
Analyzing above blood sugar test data can reach a conclusion: experiment back model group blood glucose value all is higher than normal group, and significant difference (P＜0.05 or P＜0.01), and the modeling success is described.Experiment high dose group, low dose group and model group contrast blood sugar and all obviously reduce, and equal difference is (P＜0.05 or P＜0.01) significantly, and high dose group blood sugar test value reaches 13.8% than initial blood sugar decline after raising 60d, and blood sugar decreasing effect is the most remarkable.
4.3 weight-reducing drinks are to the influence (seeing Table 3) of rat blood serum biochemical indicator
Table 3 weight-reducing drinks are to the influence (unit: mol/L) of obese rat serum biochemistry index
By the listed result of table 3 as seen, test back model group animal blood serum T-CHOL (TC), triglycerides (TG), HDL-C (HDL-cl) and LDL-C (LDL-ch) all are higher than blank group, and difference has highly significant (P＜0.01), high fat animal model modeling success is described, and the T-CHOL of experimental group rat, triglycerides, HDL-C and LDL-C all are lower than model group, difference tool highly significant (P＜0.01).
4.4 weight-reducing drinks are to the influence (seeing Table 4) of rat Lee' exponential sum fat index
Table 4 weight-reducing drinks are to the influence of rat Lee' exponential sum fat index
| Group | The Lee' index | Fat index |
| Normal group | 2.76±0.112 | 3.62±1.08 |
| Model group | 3.15±0.103 | 5.66±0.089 |
| The experiment contrast group | 2.71±0.088 | 4.03±0.113 |
| The experiment low dose group | 2.84±0.068 | 4.23±0.087 |
| Experiment high dose level | 2.73±0.110 | 4.11±0.051 |
Can get from above data: compare with normal group, model group has the significance of difference, the modeling success.Experimental group is compared with model group, Lee' exponential sum fat index significant difference (P＜0.05 or P＜0.01).
5 conclusions
Experimental result shows, Weight reducing compound drink agent of the present invention provided by the invention gavages rat, can reduce significantly that fat accumulation, the body weight that the obesity that causes because of overnutrition causes increases, blood sugar rising problem, serum TC, LDL content obviously reduce, and serum hdl content obviously raises; Fat-reducing effect is remarkable, and all raw materials all derive from food, can other health of rat not exerted an influence, for this food clinical practice provides reliable experimental basis.
Experiment two
Choose 110 obese peoples, 45 years old mean age, wherein the male sex is 48,62 of women.Give the present invention the granule of preparation, three times on the one, one time one bag (6 gram) is taken with meal.Uninterruptedly took 30 days.Take and finish back its body weight of survey and waistline, and calculate and on average fall body weight (kg) and average waistline reduction volume (cm).The experimental result statistical analysis is as follows: body weight decline 2.6 ± 1.2kg(mean ± standard deviation) total effective rate 87.6%; Waistline dwindles 1.3 ± 1.2cm(mean ± standard deviation), total effective rate 84.3%.All take the crowd of this solid beverage, and the state of mind is good, reflection increased defecation more than 87%, and defecation is unobstructed, does not occur any uncomfortable.
Experiment three
Certain middle aged women, 45 years old, body weight 67.5kg, height 156cm, fasting blood sugar is 8.7, suffers from slight diabetes, and the more than ten years are all with the not smooth old trouble of stool.Take the drink agent of the present invention's preparation, with food and drink usefulness, three times on the one, took continuously 30 days.Through health check-up: body weight drops to the 58.7kg(8.8kg that loses weight), fasting blood sugar is reduced to 5.2mmol/L(and descended 40.2% more originally), and defecation is normal during taking this solid beverage, symptoms such as constipation or diarrhoea do not occur.
Description of drawings
In order to be illustrated more clearly in the embodiment of the invention or technical scheme of the prior art, to do to introduce simply to the accompanying drawing of required use in embodiment or the description of the Prior Art below, apparently, accompanying drawing in describing below only is some embodiments of the present invention, for those of ordinary skills, under the prerequisite of not paying creative work, can also obtain other accompanying drawing according to these accompanying drawings.
Fig. 1 is the schematic block diagram of process for producing granula of the present invention;
Fig. 2 is the schematic block diagram of oral liquor of the present invention.
The specific embodiment
Below in conjunction with the accompanying drawing in the embodiment of the invention, the technical scheme in the embodiment of the invention is clearly and completely described, obviously, described embodiment only is the present invention's part embodiment, rather than whole embodiment.Based on the embodiment among the present invention, those of ordinary skills belong to the scope of protection of the invention not making the every other embodiment that obtains under the creative work prerequisite.
Embodiment 1: resistant dextrin 68.8%, L-arabinose 5%, polydextrose 22%, l-cn 0.2%, instant oolong tea powder 4%.
With reference to figure 1, the preparation flow of a kind of Weight reducing compound granule of the present invention: take by weighing resistant dextrin, L-arabinose, polydextrose, l-cn and instant oolong tea powder through sieving, mix, after the granulation, drying, being packaged into bag.
With reference to figure 2, the preparation flow of a kind of Weight reducing compound oral liquid of the present invention: take by weighing resistant dextrin, L-arabinose, polydextrose, l-cn and instant oolong tea powder, be dissolved in water, constant volume, can, seal, sterilize.
Embodiment 2: resistant dextrin 58.7%, L-arabinose 10%, polydextrose 25%, instant green tea powder 4%, konjaku flour 2%, l-cn 0.3%.
Its preparation method is with embodiment 1, so do not repeat.
Embodiment 3: resistant dextrin 37.7%, L-arabinose 5%, polydextrose 50%, instant black tea powder 4%, konjaku flour 3%, l-cn 0.3%.
Its preparation method is with embodiment 1, so do not repeat.
Embodiment 4: resistant dextrin 43.7%, L-arabinose 5%, polydextrose 45%, instant Pu'er tea powder 3%, konjaku flour 3%, l-cn 0.3%.
Its preparation method is with embodiment 1, so do not repeat.
Embodiment 5: resistant dextrin 42.7%, L-arabinose 4.5%, polydextrose 46%, lemon powder 1.5%, instant black tea powder 2%, konjaku flour 3%, l-cn 0.3%.
Embodiment 6: resistant dextrin 37%, L-arabinose 2.4%, polydextrose 20%, l-cn 3.64%, concentrated apple juice 35%, taurine 0.356%, composite B vitamin 0.034%, citric acid 1.1%, fruity flavor 0.36%, Sucralose 0.1%.
Its preparation method is with embodiment 1, so do not repeat.
Embodiment 7: resistant dextrin 54%, L-arabinose 3%, polydextrose 18%, konjaku flour 3%, concentrated apple juice 20%, taurine 0.175%, composite B vitamin 0.025%, malic acid 1.5%, fruity flavor 0.2%, acesulfame potassium 0.05%, Aspartame 0.05%.
Its preparation method is with embodiment 1, so do not repeat.
The above only is preferred embodiment of the present invention, and is in order to limit the present invention, within the spirit and principles in the present invention not all, any modification of doing, is equal to replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (8)
1. Weight reducing compound and preparation method thereof is characterized in that, comprises following component by mass percent: resistant dextrin 5-80%; L-arabinose 0.5-20%, polydextrose 1-50%, l-cn 0.1-10%; konjaku flour 0-5%; Fruit powder 0-10%, tea powder 0-10%, concentrated apple juice 0-45%; taurine 0-0.4%; composite B vitamin 0-0.5%, acidity regulator 0-2%, fruity flavor 0-0.4%, sweetener 0-1%.
2. Weight reducing compound according to claim 1 is characterized in that, described Fruit powder comprises more than one the Fruit powder in lemon powder, strawberry powder, guava powder or the orange powder.
3. Weight reducing compound according to claim 1 is characterized in that, described tea powder comprises any tea powder in green tea, black tea, oolong tea, white tea or the black tea.
4. Weight reducing compound according to claim 1 is characterized in that described composite B vitamin comprises the two or more B family vitamins in vitamin B1, vitamin B2, vitamin B6, cobalamin, nicotinic acid, pantothenic acid or the folic acid.
5. Weight reducing compound according to claim 1 is characterized in that described acidity regulator comprises more than one conditioning agents of citric acid, lactic acid, tartaric acid, malic acid, natrium citricum or potassium citrate.
6. Weight reducing compound according to claim 1 is characterized in that described sweetener comprises more than one sweet taste conditioning agents in Sucralose, Aspartame, stevioside, acesulfame potassium, xylitol or the isomalt.
7. as the preparation method of the described Weight reducing compound of claim 1 to 6, it is characterized in that the preparation process of described Weight reducing compound granule is as follows:
Take by weighing required raw material, sieve, mix, granulate, oven dry is in the aluminium foil bag of packing at last.
8. as the preparation method of the described Weight reducing compound of claim 1 to 6, it is characterized in that the preparation process of described Weight reducing compound beverage is as follows:
Take by weighing required material, heating for dissolving, constant volume, can is sealed, and autoclaving is namely.
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| CN103689317A (en) * | 2013-12-16 | 2014-04-02 | 广西博士海意信息科技有限公司 | Weight-losing and blood pressure-reducing health-nursing composition and preparation method thereof |
| CN103719756A (en) * | 2013-12-16 | 2014-04-16 | 广西博士海意信息科技有限公司 | Weight-losing health care composite and preparation method thereof |
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| CN103719756A (en) * | 2013-12-16 | 2014-04-16 | 广西博士海意信息科技有限公司 | Weight-losing health care composite and preparation method thereof |
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| CN104522469A (en) * | 2015-01-08 | 2015-04-22 | 李泼 | Functional food set meal capable of losing weight scientifically and healthily |
| CN105146267A (en) * | 2015-08-24 | 2015-12-16 | 杭州娃哈哈科技有限公司 | Composition with weight losing function and application thereof |
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Application publication date: 20130911 |