CN104256595B - A kind of many polymerizers of whole protein type enteral nutrition - Google Patents
A kind of many polymerizers of whole protein type enteral nutrition Download PDFInfo
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- CN104256595B CN104256595B CN201410503078.5A CN201410503078A CN104256595B CN 104256595 B CN104256595 B CN 104256595B CN 201410503078 A CN201410503078 A CN 201410503078A CN 104256595 B CN104256595 B CN 104256595B
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- enteral nutrition
- whole protein
- protein type
- type enteral
- polymerizers
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pediatric Medicine (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention provides a kind of many polymerizers of whole protein type enteral nutrition, energy proportioning is protein 12% 15%, fat 25% 30%, carbohydrate 55% 65%.The present invention can fully meet human body requirements, the equilibrium of comprehensive nutrition, proportioning, easy to use, and each component is had complementary advantages, mutually promoted, and to promoting patients blood plasma's protein level, improving body nutriture has positive role.It is particularly suitable for the nutritional support of the multiple disease such as peri-operation period, critical patient and underfed preventing and treating.
Description
Technical field
The present invention relates to alimentation composition, particularly to the many polymerizers of whole protein type enteral nutrition.
Technical background
The present invention relates to nutritional formulation arts, particularly to the many polymerizers of whole protein type enteral nutrition.Needed by human body
Nutrient specifically include that carbohydrate, fat, protein, inorganic salt, vitamin and dietary fiber.
This six big nutrient substance is to maintain human energy metabolism, vital movement and the most important factor of homeostasis.It is subject to
The impact of the factors such as age, sex, occupation, labor intensity, dietary habit, disease, nutrient substance is by body
As energy storage or be converted into the amount of other material and also have large change, if long-term nutrition Deficiency of Intake or take the photograph
Enter unbalanced easy initiation malnutrition or several nutrient lacks morbidity.
The malnutrition incidence rate of China inpatient is 10%～60%, and underfed risk is 36%～72%.
The infection risk causing patient is increased by malnutrition, extends the hospital stays of patient, increases the medical care expenses of patient
With etc..Enteral nutrition is the one that current people generally admit nutrition treatment method safe, economic, effective,
Have and meet human body physiological state, contribute to maintaining alimentary canal shape and function, easy to operate, few intercurrent disease etc.
Advantage, is increasingly becoming the important component part of clinic nutrition treatment.
Nutrient contained by the many polymerizers of whole protein type enteral nutrition is comprehensive, equilibrium, is widely used in peri-operation period sick
The nutritional support of the patients such as people, critical patient, persistent vegetative state and treatment, it is possible to as meal supplement or replace
For meals.Current domestic enteral nutrition preparation used is mainly based on import, and price is higher, unsuitable in
Taste of Chinese people, intestinal adaptability；Domestic relevant enteral nutrition quality is uneven, and in enteral nutrition, protein comes
Source great majority are casein, and casein is a kind of macromole type, densification, the protein of indigestibility decomposition, at stomach
In easily form curdled milk, obstruction is digested and assimilated；Adipose-derived it mostly is single Vegetable oil lipoprotein or hydrogenation vegetable fat oils and fats,
Human body nutritional need linolenic to multiple fatty acid, particularly linoleic acid and a-can not be met.Need research and development suitable
Close Chinese taste, intestinal adaptability and the enteral nutrition (intacted protein) of metabolic characteristics.
Summary of the invention
Present invention aim at providing a kind of many polymerizers of whole protein type enteral nutrition
It is an object of the invention to be realized by following measures:
A kind of many polymerizers of whole protein type enteral nutrition, energy proportioning is protein 12%-15%, fat
25%-30%, carbohydrate 55%-65%.Can fully meet human body requirements.Be particularly suitable for peri-operation period,
The nutritional support of the multiple disease such as critical patient and underfed preventing and treating.
The many polymerizers of above-mentioned whole protein type enteral nutrition, described fat, satisfied fatty acid, monounsaturated fatty acid,
Content of polyunsaturated fatty acid ratio is 1: 1: 1, and ω-6 is fatty acid: ω-3 is ratio 4-10 of fatty acid: 1,
In order to be more suitable for the nutritional characteristic of Chinese's health, ω-6: ω-3 preferably 4-6: 1, more preferably
5∶1.On the premise of meals always fat energy supply is reduced to 30%, decrease satisfied fatty acid takes the photograph people's amount, does not surpasses
Cross the 10% of gross energy；Limit trans fatty acid takes the photograph people.The whole protein type enteral nutrition product that presently, there are,
How using Semen Maydis oil or soybean oil as adipose-derived.But according to we have discovered that: Fructus Maydis oil, soybean oil,
Oleum Helianthi is rich in omega 6 polyunsaturated fatty acid, but lacking ω-3 is a-linolenic acid, the ratio of ω-6: ω-3
It is worth unreasonable；Olive oil, Oleum Camelliae are rich in monounsaturated fatty acid, but are fatty acid without ω-3, single
Edible oil kind is as the adipose-derived fatty acid nutritive demand that can not meet human body.The present invention is directed to market product deposit
The unbalanced problem of fatty powder proportioning, by Oleum Cocois, Petiolus Trachycarpi oil, Semen Maydis oil, soybean oil, Oleum Helianthi,
Olive oil, Oleum Camelliae, Semen Lini oil, Oleum Perillae in combination of two or more after mix with emulsifying agent and water after warp
Homogenizing obtains emulsion；Then emulsion is atomized into drop and is injected to the spray drying containing powder embedding material
Equipment is dried, then obtains fatty powder through screening, its fat content 30%-70%.Preferably, fat
Powder raw material is Oleum Cocois and/or Petiolus Trachycarpi oil, Semen Maydis oil and/or soybean oil and/or Oleum Helianthi, olive oil and/
Or Oleum Camelliae, Semen Lini oil and/or Oleum Perillae.In fatty powder, all kinds of fatty acids realize equilibrium proportioning, more preferably
Play a role.
Albumen of the present invention source is high-quality protein, is formed, wherein by lactalbumin and soybean protein are compounding
Both proportionings are optionally lactalbumin: soybean protein isolate 1: 9-9: 1, it is contemplated that both Synergistics
Effect maximizes, and its proportioning is more preferably lactalbumin: soybean protein isolate 4: 6-8: 2, more preferably
1: 1, with mass ratio range.Wherein the source of lactalbumin is concentrated lactoalbumin, sepg whey albumen or hydrolysis
One or more in lactalbumin, the source of soybean protein is soybean protein isolate.High-quality protein refers to amino
Acid-utilising rate is high, and various amino acid whose ratios meet the amino acid whose ratio of human body protein, through digestibility correction
AAS (PDCAAS) reaches the albumen of 1.0.Proteinaceous nutrient biological value more puts to death protein
Amino acid pattern, certain essential amino acids deficiency or surplus have a strong impact on the nutritive value of protein equally.This
In bright middle whey protein concentrate and soybean protein isolate, essential amino acid pattern is more satisfactory, accounts for its aminoacid respectively
The 40.8% and 38.5% of total amount, the Ideal Amino Acid Pattern phase that its essential amino acid pattern and FAO/WHO recommend
Closely.But, the phenylalanine of lactalbumin and tyrosine are significantly lower than FAO/WHO pattern, i.e. milk surum concentrate egg
The first white limiting amino acid is phenylalanine and tyrosine, and phenylalanine and tyrosine contain in soybean protein
Measure the abundantest；The methionine of soybean protein and cystine then separate significantly lower than FAO/WHO pattern, i.e. Semen sojae atricolor
First limiting amino acid of albumen is methionine and cystine, and methionine and cystine are in whey protein concentrate
Content is the abundantest.Aminoacid complementation is reached by rationally compounding to concentrated lactoalbumin and soybean protein isolate, from
And improve the nutritive value of protein.The present invention is directed to existing market product protein and be mainly derived from single albumen
Matter (such as casein, lactalbumin, the one of soybean protein), the undesirable present situation of amino acid pattern changes
Enter, two kinds of high-quality proteins of lactalbumin and soybean protein are compounded.The present invention rationally compounding by both,
Utilizing synergistic function between the two, (SRCAA reaches to make the score of ratio coefficient of amino acid of final mixed protein
To 86.7) all have substantially than single protein (concentrated lactoalbumin 82.0, soybean protein isolate 76.6)
Raising, illustrate the aminoacid composition of mixed protein and content close to ideal protein amino acid pattern, overall
Nutritive value is improved.
The many polymerizers of above-mentioned whole protein type enteral nutrition, make by weight including following raw material: fatty powder
20-45 part；Maltodextrin 20-40 part；Lactalbumin 2-10 part；Soybean protein 4-14 part；Glucose 5-10
Part.
Above-mentioned maltodextrin DE value is 10 to 22, and preferably DE is the maltose dextrose of 13-17, and sugariness is relatively
Low, it is difficult to make moist, it is difficult to brown stain, modest viscosity, transparency is preferable.Maltodextrin effect in formula is not
It is only to provide energy for body, moreover it is possible to organoleptic attribute and stability on product produce impact.Embody a concentrated reflection of wheat
The DE value of bud dextrin is to the suspending power of outward appearance, mouthfeel, color and luster and solution of finished product, viscosity and transparent
Degree is respectively provided with significant impact, therefore selects the maltodextrin raw material of suitable DE value to have great importance, this
Invention fully takes into account the suitability and the storage stability of products taste.When maltodextrin DE value is lower, obtain
Though the many polymerizers of nutrition be difficult to make moist, it is difficult to brown stain, suspending power is strong, but product is substantially without sweet taste, and
Viscosity is relatively big, and transparency is relatively low.When DE value is higher, the many polymerizers of nutrition slightly sweet taste, has certain moisture absorption,
Transparency is higher, and viscosity is relatively low, but browning reaction can occur.
The many polymerizers of above-mentioned whole protein type enteral nutrition, also include dietary fiber, its consumption in many polymerizers
For 3-7 part.The present invention is on the basis of research dietary fiber rational proportion, in conjunction with water in Chinese residents diet not
The feature that ratio shared by soluble dietary fiber is little, adjusts water soluble dietary fiber in formula fine with insoluble meals
The ratio of dimension is 2: 1-1: 3, preferably 1: 1.Wherein said water soluble dietary fiber derives from inulin, poly-Portugal
In grape sugar, oligomeric galactose, oligofructose, polyfructosan, cottonseed sugar, oligomeric xylose, oligomeric isomaltose
One or more combination, described insoluble dietary fiber derives from resistant dextrin, soybean fiber, corn bran
One or more in fiber, beet fiber, Semen Tritici aestivi fiber, Testa Tritici fiber, Herba avenae fatuae fiber, apple fiber.
Utilize the synergism between multiple dietary fiber, reach regulating intestinal canal function, reduce enteral nutrition dependency abdomen
Rush down.It is thin that dietary fiber occurs zymolysis, generation to have maintenance mucous membrane of colon epithelium under the flora effect of human colon road
In the generation of born of the same parents, penetrates and updates, promoting water and sodium absorption, the short-chain fatty acid of function of regulating intestinal canal, in enteral nutrition
Preparation adds dietary fiber there is the function reducing enteral nutrition induced diarrhea, improving intestinal.Meals
The significance of fiber physiological function has much relations with water solublity in dietary fiber and water-insoluble ratio.Cause
This, while noticing that dietary fiber takes the photograph people's amount, should also be noted that water soluble dietary fiber amount in holding dietary fiber
Balance.
The many polymerizers of above-mentioned whole protein type enteral nutrition, also include probiotic bacteria 0.02-0.2 part, by weight,
Described probiotic bacteria includes bacillus acidophilus, bifidobacterium longum, Lactobacillus paracasei, lactobacillus rhamnosus, fermentation
One or more in lactobacillus, lactobacillus helveticus or streptococcus thermophilus.Research proves probiotic bacteria and above-mentioned oligomerization
Sugar (prebiotics) is used in combination can have synergistic function.On the one hand, oligosaccharide is as some probiotic bacteria
The increment factor, strengthen probiotic bacteria competitive advantage；On the other hand, the digestive enzyme of probiotic bacteria secretion makes oligosaccharide
Digestion is monosaccharide further, is directly utilized by probiotic bacteria or body.The present invention is adding dietary fiber (prebiotics)
While, it is especially added with multiple probiotic bacteria, promotes the growth of enteral lactic acid bacteria, play conditioning intestinal balance, adjust
The function of joint human immune system；The synergism utilizing both reaches to adjust intestinal microbial population, reduces abdomen further
The purpose rushed down.
The present invention is especially added with arginine and the glutamine with immunologic function, and combines tradition integration of edible and medicinal herbs reason
Opinion add integration of edible and medicinal herbs raw material, described integration of edible and medicinal herbs raw material include the one in Radix Ginseng powder, date powder, Colla Corii Asini powder or
Several.Preferably, arginine≤6 part, glutamine≤6 part, integration of edible and medicinal herbs raw material 2-8 part, ensureing machine
Improve the rehabilitation of patient's autoimmunity, beneficially patient on the basis of body nutritional need and improve the quality of living.This
In invention, rich in cyclic adenosine monophosphate (cAMP) and triterpenoid compound, there is anticancer growth with numerous
The function grown；Also there is the lymphopoietic function of promotion rich in polysaccharide, to antioxidation, defying age, raising
Immunity of organisms has important function, and polysaccharide, cAMP, vitamin, mineral, to body hemopoietic system, have
Well benefiting action；Further, propagation and the differentiation of body hematopoietic stem cell can be promoted, there is good enriching blood
Effect, Colla Corii Asini also has raising cellular immunization and the function of humoral immunization；Further, there are invigorating the spleen to benefit the lung, big complement
Gas, effect of promoting the production of body fluid and inducing sedation of the mind Fructus Alpiniae Oxyphyllae, to nervous system, small intestinal transmitting function, hormonal system, immune system,
The aspects such as signal conduction, defying age, blood sugar lowering there is appreciable impact.In the present invention, Multiple components is at poly
In mixture mutually coordinated, give full play to useful usefulness.For peri-operation period colorectal carcinoma patient, can improve thin
Born of the same parents' immune level, within postoperative 7th day, CD4/CD8 ratio is significantly raised.
Raw material of the present invention adds xanthan gum 0.2-0.8 part the most by weight.Whole protein type of the present invention
The insoluble dietary fiber added in enteral nutritional composition and mineral, it is heavy easily to occur during reconstituting
Form sediment, be unfavorable for the absorption of nutritional labeling.In order to improve the structural state of product, improve product viscosity and suspend steady
Qualitative, by adjusting the addition of xanthan gum, product can be with stable suspersion more than 8 hours after reconstituting.
The many polymerizers of whole protein type enteral nutrition of the present invention with fatty powder, lactalbumin, soybean protein, maltodextrin and
Glucose, multivitamin, mineral and the enteral nutrition of dietary fiber composition comprehensive nutrition equilibrium, can meet
The nutritional need of human body.
The many polymerizers of above-mentioned whole protein type enteral nutrition, including fatty powder 20-45 part, maltodextrin 40-50
Part, lactalbumin 2-10 part, soybean protein 4-14 part, glucose 5-10 part, dietary fiber 3-7 part (chrysanthemum
Powder, polydextrose, oligomeric galactose, oligofructose, polyfructosan, cottonseed sugar, oligomeric xylose, oligomeric different
Maltose), compound vitamin 3-5 part, composite mineral matter 5-7 part, date powder 4 parts, 1.5 parts of Colla Corii Asini powder,
Radix Ginseng powder 0.5 part, essence 0.1-0.4 part.Above-mentioned composite mineral matter by sodium, potassium, calcium, magnesium, phosphorus, zinc,
Ferrum, copper, manganese, iodine, selenium, chlorine form, and above-mentioned compound vitamin is by vitamin A, vitamin D, vitamin
E, vitamin K, vitamin B1, vitamin B2, vitamin B6, vitamin B12, nicotiamide, pantothenic acid,
Vitamin C, folic acid, biotin, taurine composition a kind of comprehensive nutrition, the many polymerizers of enteral nutrition of equilibrium.
The present invention is mainly composed of protein, fat, carbohydrate, vitamin, mineral, dietary fiber,
And rationally add human body various nutrients needed for other, including 14 kinds of vitamin, 12 kinds of mineral and 8 kinds of meals
Food fiber.
The many polymerizers of above-mentioned whole protein type enteral nutrition, for peri-operation period nutritional support, critical illness nutritional support,
The nutritional support of persistent vegetative state and rehabilitation or the purposes of malnutrition preventing and treating.
Beneficial effect
1. the present invention is with disease nutritional support treatment for relying on, and selecting the maltodextrin being easily soluble in water is carbon hydrate
Thing main source, originates with lactalbumin, soybean protein isolate for albumen, optimizes amino acid pattern, improves egg
White matter bioavailability.Constituted for fat with middle long-chain fatty acid, directly absorbed, quick energy supply, without lactose,
Avoid lactose intolerance to cause diarrhoea, add compound vitamin, several mineral materials and dietary fiber composition nutrition complete
Face, equilibrium, low-cost whole protein type enteral nutrition preparation, be clinically used for improving patient's malnutrition, fall
Low nutrition risk, improves immunity of organisms, meets needed by human body nutrition.
2. the present invention meets DRIs, and the equilibrium of comprehensive nutrition, proportioning, price are just
Preferably.
The many polymerizers of whole protein type enteral nutrition the most provided by the present invention, comprehensive nutrition, proportioning equilibrium, easy to use,
Each component is had complementary advantages, is mutually promoted, and to promoting patients blood plasma's protein level, improving body nutriture has long-pending
Pole acts on.The many polymerizers of whole protein type enteral nutrition provided by the present invention are used for esophageal surgery patient's nutritional support
Treatment 7d, patient's blood plasma ALB, PA level is significantly raised, shows that it is to improving patients blood plasma's protein level effect
Fruit is substantially.
4. the present invention rationally compounding by two kinds of high-quality proteins (soybean protein isolate and lactalbumin), utilizes it to assist
Same potentiation, makes the score of ratio coefficient of amino acid (SRCAA) of final mixed protein be greatly improved, reaches
To 86.7 (concentrated lactoalbumin 82.0, soybean protein isolates 76.6), overall nutrient protein is worth and is carried
High.
5. in inventive formulation, water solublity and water insoluble dietary fiber ratio, close to 1: 1, and are especially added with probiotic bacteria,
Both synergism are jointly safeguarded function of intestinal canal, are reduced the generation of gastrointestinal complication.The whole protein type of the present invention
The many polymerizers of enteral nutrition are used for esophageal surgery patient's nutritional support treatment 7d, with Nutrison Fibre for comparison, and can be complete
Power is the enteral nutrition (intacted protein) that standard type and clinic are conventional, its significant nutritional support effect and safety
Being confirmed in clinic, Nutrison Fibre and this test enteral nutrition belong to same type, therefore select Nutrison Fibre
The comparison tested as this, result shows two groups of patient's gastrointestinal complications such as abdominal distention, Nausea and vomiting, constipation
Incidence rate is identical, shows that the many polymerizers of whole protein type enteral nutrition of the present invention meet esophagus patients during peri gastrointestinal
Road metabolic characteristic, well adapting to property.
Detailed description of the invention
Below by embodiment, the present invention is specifically described, it is necessary to it is pointed out here that, below implement
Example is served only for being further described the present invention, it is impossible to be interpreted as limiting the scope of the invention, this neck
The present invention can be made some nonessential improvement and adjustment according to the invention described above content by field technique personnel.
Embodiment 1
A kind of many polymerizers of whole protein type enteral nutrition, composed of the following components:
Fatty powder 33 parts (by Oleum Cocois, soybean oil, olive oil, Semen Lini oil according to 2: 4.5: 2: 1 weight
After amount is than mixing, after mixing with sodium caseinate, obtain emulsion through homogenizing；Then emulsion is atomized into liquid
Drip in the spray drying device being injected to containing powder embedding material and be dried, then obtain fat through screening
Powder, fat content is 50%)；Carbohydrate: maltodextrin 20 parts, glucose 5.4 parts；Albumen:
Lact albumin hydrolysate 5 parts, soybean protein isolate 14 parts；Dietary fiber: inulin 1.5 parts, polydextrose 1
Part, oligomeric xylose 0.5 part, resistant dextrin 2 parts, Semen Tritici aestivi fiber 1 part；Probiotic bacteria 0.1 part is (addicted to yogurt bar
Bacterium, bifidobacterium longum, Lactobacillus paracasei, lactobacillus rhamnosus, Lactobacillus fermenti, lactobacillus helveticus and addicted to
Hot streptococcus mixes according to equal proportion, makes viable count in probiotic powder reach 1 × 1010More than CFU), because emphasizing
Herbicide interactions with dietary fiber, then consider above-mentioned dietary fiber and the composition of this probiotic bacteria select be have corresponding
Property.Compound vitamin 4 parts；Composite mineral matter 4 parts；Glutamine 3.3 parts；Date powder 3 parts；Colla Corii Asini powder
1g；Xanthan gum 0.3 part；0.2 part of essence, by weight.
After testing, preferably maltose dextrose DE is 16, the score of ratio coefficient of amino acid (SRCAA of mixed protein
Reach 86.7), energy proportioning is protein 13%, fat 30%, carbohydrate 57%.
The many polymerizers of this whole protein type enteral nutrition (seminar) is used for esophageal surgery patient, egg whole with standard
White type enteral nutrition (matched group, Nutrison Fibre, Nutricia NV) is compared, and accepts during two groups of patient's researchs
Enteral Nutritional Support 10 days, two groups of patients serum's ALB, PA levels are apparently higher than operation consent, and total gallbladder is solid
The change of alcohol, triglyceride, creatinine, blood urea nitrogen, respectively refers between two groups without significant with operation consent comparing difference
Mark comparing difference, without significant, shows that the many polymerizers of this whole protein type enteral nutrition are providing energy, raising
Plasma protein concentration aspect and Nutrison Fibre have equivalent effect, can significantly improve the nutrition shape of esophagus patients during peri
Condition (table 1).Experimental data proves: this result of study shows that this whole many polymerizer of albumen enteral nutrition can improve
Esophagus patients during peri malnutrition, is a kind of effective enteral nutrition.
Seminar and matched group enteral nutrition treatment effectiveness comparison
* P ＜ 0.05 is compared with operation consent
Note: albumin (ALB)；Prealbumin (PA)；Creatinine (Cr)；Blood urea nitrogen (BUN) T-CHOL (TC)；
Triglyceride (TG)
Embodiment 2
A kind of many polymerizers of whole protein type enteral nutrition, composed of the following components:
Fatty powder 25 parts (by Petiolus Trachycarpi oil, Semen Maydis oil, Oleum Camelliae, Oleum Perillae according to 2: 4.5: 2: 1 weight
After amount is than mixing, after mixing with sodium caseinate, obtain emulsion through homogenizing；Then emulsion is atomized into liquid
Drip in the spray drying device being injected to containing powder embedding material and be dried, then obtain fat through screening
Powder, fat content is 50%)；
Carbohydrate: maltodextrin 30 parts, glucose 8.5 parts；
Albumen: 4 parts of sepg whey albumen, soybean protein isolate 12 parts；
Dietary fiber: inulin 1 part, oligomeric xylose 0.5 part, polydextrose 1.5 parts, Herba avenae fatuae fiber 1 part,
Soybean fiber 2 parts；
Probiotic bacteria 0.05 part；(bacillus acidophilus, bifidobacterium longum, Lactobacillus paracasei, rhamnose breast bar
Bacterium, Lactobacillus fermenti, lactobacillus helveticus and streptococcus thermophilus mix according to equal proportion, make viable bacteria in probiotic powder
Number reaches 1 × 1010More than CFU)
Compound vitamin 4 parts；Composite mineral matter 4 parts；Glutamine 3.3 parts；2 parts of Colla Corii Asini powder；Radix Ginseng powder
0.5g；Xanthan gum 0.45 part；0.2 part of essence, by weight.
The many polymerizers of whole protein type enteral nutrition provided by the present invention are used for esophageal surgery patient's nutritional support treatment
7d, patient's blood plasma ALB, PA level is significantly raised, and to improving, patients blood plasma's protein level effect is obvious.And
Meet esophagus patients during peri gastrointestinal tract feature, well adapting to property.
Embodiment 3
A kind of many polymerizers of whole protein type enteral nutrition, including following components:
Fatty powder 30 parts is (by Petiolus Trachycarpi oil, Oleum Helianthi, Oleum Camelliae, Oleum Perillae according to 2: 4.5: 2: 1
After weight ratio mixing, after mixing with sodium caseinate, obtain emulsion through homogenizing；Then emulsion is atomized into
Drop is injected in the spray drying device containing powder embedding material be dried, then obtains fat through screening
Powder, fat content is 50%)；
Carbohydrate: maltodextrin 23 parts, glucose 7 parts；
Albumen is originated: concentrated lactoalbumin 5 parts, 2 parts of sepg whey albumen, soybean protein isolate 7.5 parts；
Dietary fiber: cottonseed sugar 2 parts, oligomeric isomaltose 1 part, Semen Tritici aestivi fiber 2 parts, resistant dextrin 1
Part；
Compound vitamin 2 parts；Composite mineral matter 4 parts；Glutamine 3 parts；Date powder 4 parts；Colla Corii Asini powder 1.5
Part；Radix Ginseng powder 0.5 part；Xanthan gum 0.3 part；0.2 part of essence, by weight.
The many polymerizers of whole protein type enteral nutrition provided by the present invention are used for esophageal surgery patient's nutritional support treatment
7d, patient's blood plasma ALB, PA level is significantly raised, and to improving, patients blood plasma's protein level effect is obvious.And
Meet esophagus patients during peri gastrointestinal tract feature, well adapting to property.
Embodiment 4
A kind of many polymerizers of whole protein type enteral nutrition, including following components:
Fatty powder 42 parts；(by Oleum Cocois, soybean oil, Oleum Camelliae, Oleum Perillae according to 2: 4.5: 2: 1 weight
After mixing, after mixing with sodium caseinate, obtain emulsion through homogenizing；Then emulsion is atomized into drop
It is injected in the spray drying device containing powder embedding material be dried, then obtains fatty powder through screening,
Fat content is 50%) carbohydrate: maltodextrin 21.8 parts, glucose 5 parts；
Albumen: lact albumin hydrolysate 4 parts, 2 parts of sepg whey albumen, soybean protein isolate 10.5 parts；
Dietary fiber: oligomeric xylose 0.5 part, polydextrose 1.5 parts, resistant dextrin 1 part, apple fiber 1
Part；
Probiotic bacteria 0.2 part (bacillus acidophilus, bifidobacterium longum, Lactobacillus paracasei, lactobacillus rhamnosus,
Lactobacillus fermenti, lactobacillus helveticus and streptococcus thermophilus mix according to equal proportion, make viable count in probiotic powder reach
To 1 × 1010More than CFU)；
Compound vitamin 2 parts；Composite mineral matter 3 parts；Glutamine 3.3 parts；Date powder 3.5 parts；Colla Corii Asini powder 1
Part；Radix Ginseng powder 0.5 part；Xanthan gum 0.2 part；0.3 part of essence, by weight.
The many polymerizers of whole protein type enteral nutrition provided by the present invention are used for esophageal surgery patient's nutritional support treatment
7d, patient's blood plasma ALB, PA level is significantly raised, and to improving, patients blood plasma's protein level effect is obvious.And
Meet esophagus patients during peri gastrointestinal tract feature, well adapting to property.
Claims (13)
1. the many polymerizers of whole protein type enteral nutrition, it is characterised in that: energy proportioning is protein 12%-15%, fat 25%-30%, carbohydrate 55%-65%；Make by weight including following raw material: fatty powder 20-45 part, maltodextrin 20-40 part, lactalbumin 2-10 part, soybean protein 4-14 part, glucose 5-10 part, dietary fiber 3-7 part, probiotic bacteria 0.02-0.2 part；
Described fatty powder be by Oleum Cocois, Petiolus Trachycarpi oil, Semen Maydis oil, soybean oil, Oleum Helianthi, olive oil, Oleum Camelliae, Semen Lini oil, Oleum Perillae in combination of two or more after mix with emulsifying agent and water after obtain emulsion through homogenizing；Then emulsion is atomized into drop be injected in the spray drying device containing powder embedding material be dried, then obtains fatty powder through screening；
Protein source is in lactalbumin and soybean protein；In described fat, satisfied fatty acid, monounsaturated fatty acid, content of polyunsaturated fatty acid are than for 1:1:1.
2. the many polymerizers of whole protein type enteral nutrition as claimed in claim 1, it is characterised in that: ω-6 is fatty acid: ω-3 is that the content ratio of fatty acid is for 4-10:1.
3. the many polymerizers of whole protein type enteral nutrition as claimed in claim 1, it is characterised in that: ω-6 is fatty acid: ω-3 be fatty acid be 4-6:1.
4. the many polymerizers of whole protein type enteral nutrition as claimed in claim 1, it is characterised in that: ω-6 is fatty acid: ω-3 be fatty acid be 5:1.
5. the many polymerizers of whole protein type enteral nutrition as described in claim 1, it is characterised in that: lactalbumin: soybean protein is 4:6-1:1.
6. the many polymerizers of whole protein type enteral nutrition as described in claim 1-5 is arbitrary, it is characterized in that: the source of described lactalbumin is one or more in concentrated lactoalbumin, sepg whey albumen or lact albumin hydrolysate, and the source of soybean protein is soybean protein isolate.
7. the many polymerizers of whole protein type enteral nutrition as described in claim 1-5 is arbitrary, it is characterised in that: described maltodextrin DE value is 10 to 22.
8. the many polymerizers of whole protein type enteral nutrition as claimed in claim 7, it is characterised in that: described maltodextrin DE value is 13-17.
9. the many polymerizers of whole protein type enteral nutrition as described in claim 1-5 is arbitrary, it is characterised in that: in described dietary fiber, the content of water soluble dietary fiber and insoluble dietary fiber is than for 2:1-1:3；Described water soluble dietary fiber derives from one or more in inulin, polydextrose, oligomeric galactose, oligofructose, polyfructosan, cottonseed sugar, oligomeric xylose, oligomeric isomaltose, and described insoluble dietary fiber derives from one or more in resistant dextrin, soybean fiber, corn bran fiber, beet fiber, Semen Tritici aestivi fiber, Testa Tritici fiber, Herba avenae fatuae fiber, apple fiber.
10. the many polymerizers of whole protein type enteral nutrition as described in claim 1-5 is arbitrary, it is characterised in that: described probiotic bacteria includes one or more in bacillus acidophilus, bifidobacterium longum, Lactobacillus paracasei, lactobacillus rhamnosus, Lactobacillus fermenti, lactobacillus helveticus or streptococcus thermophilus.
The 11. many polymerizers of the whole protein type enteral nutrition as described in claim 1-5 is arbitrary, it is characterized in that: also include arginine and glutamine, integration of edible and medicinal herbs raw material, described integration of edible and medicinal herbs raw material includes one or more in Radix Ginseng powder, date powder, Colla Corii Asini powder, arginine≤6 part, glutamine≤6 part, integration of edible and medicinal herbs raw material 2-8 part, with mass ratio range.
The 12. many polymerizers of the whole protein type enteral nutrition as described in claim 1-5 is arbitrary, it is characterised in that: also include xanthan gum 0.2-0.8 part, by weight.
The 13. many polymerizers of whole protein type enteral nutrition as described in claim 1-12 is arbitrary are in peri-operation period nutritional support, critical illness nutritional support, nutritional support and rehabilitation or the purposes of malnutrition preventing and treating of persistent vegetative state.
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