CN112472761A - Oral Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases - Google Patents

Abstract

The invention discloses an oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases, which comprises, by weight, 3-5 parts of dried orange peel, 2-4 parts of pseudo-ginseng, 2-4 parts of pinellia ternate, 3-6 parts of ginseng, 4-6 parts of American ginseng, 8-10 parts of polygonum multiflorum, 8-12 parts of ligusticum chuanxiong hort, 3-5 parts of safflower, 2-5 parts of bighead atractylodes rhizome, 5-7 parts of poria cocos, 4-8 parts of angelica sinensis, 4-6 parts of white paeony root, 3-6 parts of mangnolia officinalis, 3-5 parts of cassia twig, 7-10 parts of honey-fried licorice root, 5-8 parts of red yeast rice, 1-4 parts of grifola, 2-5 parts of semen plantaginis and 8-12 parts of prepared rehmannia root. The oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases prepared by the method can effectively prevent and treat cardiovascular and cerebrovascular diseases, and improve the sequelae of cerebral apoplexy, coronary heart disease and postoperative rehabilitation effect.

Description

Oral Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases

Technical Field

The invention relates to the technical field of medicaments for treating cardiovascular and cerebrovascular diseases, in particular to an oral Chinese medicament for preventing and treating cardiovascular and cerebrovascular diseases.

Background

Cardiovascular and cerebrovascular diseases are the general names of cardiovascular and cerebrovascular diseases, and generally refer to ischemic or hemorrhagic diseases of heart, brain and systemic tissues caused by hyperlipidemia, blood viscosity, atherosclerosis, hypertension and the like. The cardiovascular and cerebrovascular diseases are common diseases seriously threatening the health of human beings, particularly the middle-aged and old people over 50 years old, have the characteristics of high morbidity, high disability rate and high mortality, even if the most advanced and perfect treatment means at present are applied, more than 50 percent of cerebrovascular accident survivors still can not completely self-care, the number of people dying from the cardiovascular and cerebrovascular diseases in each year in the world reaches 1500 thousands, the patients live at the first position of various causes of death, and the cardiovascular and cerebrovascular diseases are the manifestations of systemic vasculopathy or systemic vasculopathy in the heart and the brain. The etiology is mainly divided into 4 aspects: vascular factors such as atherosclerosis, hypertensive arteriosclerotic disease and arteritis; blood flow dynamics factors such as hypertension; dyshemorheology such as hyperlipidemia and diabetes; blood component factors such as leukemia, anemia and thrombocytosis;

the existing related traditional Chinese medicine is not convenient to take for a long time, and the drug effect is easy to lose after being repeatedly decocted and soaked, so that an improved oral traditional Chinese medicine is needed.

Disclosure of Invention

The invention mainly aims to provide an oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases, and aims to solve the problems that the existing related medicines have insufficient effects of preventing and treating the cardiovascular and cerebrovascular diseases, certain safety risks exist when the medicines are taken for a long time, the medicines are not convenient to take, the medicine effect is lost after repeated decoction and soaking, and the like.

In order to achieve the purpose, the invention adopts the technical scheme that: an oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases comprises, by weight, 3-5 parts of dried orange peel, 2-4 parts of pseudo-ginseng, 2-4 parts of pinellia ternate, 3-6 parts of ginseng, 4-6 parts of American ginseng, 8-10 parts of polygonum multiflorum, 8-12 parts of ligusticum chuanxiong hort, 3-5 parts of safflower, 2-5 parts of bighead atractylodes rhizome, 5-7 parts of poria cocos, 4-8 parts of angelica sinensis, 4-6 parts of radix paeoniae alba, 3-6 parts of mangnolia officinalis, 3-5 parts of cassia twig, 7-10 parts of honey-fried licorice root, 5-8 parts of red yeast rice, 1-4 parts of grifola, 2-5 parts of semen plantaginis and 8-12 parts of prepared rehmannia root.

Preferably, the traditional Chinese medicine composition comprises 3.5-4.5 parts of dried orange peel, 2.5-3.5 parts of pseudo-ginseng, 2.5-3.5 parts of pinellia ternate, 4-5 parts of ginseng, 4.5-5.5 parts of American ginseng, 8.5-9.5 parts of polygonum multiflorum, 9-11 parts of ligusticum chuanxiong hort, 3.5-4.5 parts of safflower, 3-4 parts of bighead atractylodes rhizome, 5.5-6.5 parts of poria cocos, 5-7 parts of angelica sinensis, 4.5-5.5 parts of radix paeoniae alba, 4-5 parts of mangnolia officinalis, 3.5-4.5 parts of cassia twig, 8-9 parts of honey-fried licorice root, 6-7 parts of red yeast rice, 2-3 parts of grifola, 3-4 parts of semen plantaginis and 9-11.

The preparation method of the oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases comprises the following steps:

the method comprises the following steps: mixing ginseng, American ginseng, polygonum multiflorum, bighead atractylodes rhizome, poria cocos, angelica sinensis, mangnolia officinalis and prepared rehmannia root in a reaction kettle, adding a proper amount of sterile water in the mixing process, and mixing for 20-30min to enable the materials to be sticky to obtain a mixture;

step two: sequentially adding pericarpium Citri Tangerinae, Notoginseng radix, rhizoma Pinelliae, ramulus Cinnamomi, Polyporus, rhizoma Ligustici Chuanxiong and radix Paeoniae alba into the above mixture, and mixing for 35-45min, continuously heating to 75-85 deg.C during mixing process, and maintaining for 8-12min to obtain further mixture;

step three: continuously adding the safflower, the honey-fried licorice root, the red yeast rice and the plantain seed into the mixture obtained in the second step, adding a proper amount of sterile water again, continuously mixing after adding, heating to 120 ℃ and 130 ℃, keeping the temperature for 10-15min, and taking out;

step four: drying the materials mixed in the steps, wherein the drying process is carried out in an aseptic state, and the drying time is 25-35min, so that the water content of the mixture is not higher than 8%;

step five: crushing the dried mixture again, and keeping the particle size of the crushed mixture to be 120 meshes;

step six: detecting a finished product, weighing after the finished product is detected to be qualified, independently packaging by using sterile gauze according to the dosage, and selecting a sterile environment in the packaging state;

step seven: and (4) repackaging the gauze-wrapped traditional Chinese medicine powder by using a glass ware to obtain the oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases.

Preferably, the preparation method of the dried orange peel comprises the following steps:

taking 300g of orange peel, repeatedly cleaning with clear water, and draining for 3-5 min;

drying the orange peel with the drained surface at a low temperature, wherein the low-temperature drying temperature is not higher than 40-45 ℃;

airing the orange peels dried at the low temperature for a long time, and turning over the orange peels during the airing process to enable the surfaces of the orange peels to be reddish brown;

and slicing the dried orange peel for a long time and crushing for later use to obtain the required dried orange peel.

Preferably, the preparation method of the honey-fried licorice root comprises the following steps:

taking 250g of liquorice, cleaning and transversely cutting into a circular sheet;

uniformly stirring and soaking the cut liquorice in honey for 3.5-4.5 hours;

turning and heating the licorice soaked in the honey until the licorice turns into a scorched state, and removing excessive water;

and (5) cooling to obtain the required honey-fried licorice root.

The invention has the following beneficial effects:

the oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases prepared by the method can effectively prevent and treat cardiovascular and cerebrovascular diseases, and improve the sequelae of cerebral apoplexy, coronary heart disease and postoperative rehabilitation effect.

The oral traditional Chinese medicine prepared by the method contains various traditional Chinese medicine components, has wide component content, full effect, great help effect on human body and safe and reliable taking.

The oral traditional Chinese medicine prepared by the method is convenient to take, only quantitative powder needs to be brewed for taking, and the medicine effect is quickly absorbed and takes effect quickly.

Of course, it is not necessary for any product in which the invention is practiced to achieve all of the above-described advantages at the same time.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1

An oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases comprises, by weight, 3-5 parts of dried orange peel, 2-4 parts of pseudo-ginseng, 2-4 parts of pinellia ternate, 3-6 parts of ginseng, 4-6 parts of American ginseng, 8-10 parts of polygonum multiflorum, 8-12 parts of ligusticum chuanxiong hort, 3-5 parts of safflower, 2-5 parts of bighead atractylodes rhizome, 5-7 parts of poria cocos, 4-8 parts of angelica sinensis, 4-6 parts of radix paeoniae alba, 3-6 parts of mangnolia officinalis, 3-5 parts of cassia twig, 7-10 parts of honey-fried licorice root, 5-8 parts of red yeast rice, 1-4 parts of grifola, 2-5 parts of semen plantaginis and 8-12 parts of prepared rehmannia root.

Wherein, comprises 3.5 to 4.5 parts of dried orange peel, 2.5 to 3.5 parts of pseudo-ginseng, 2.5 to 3.5 parts of pinellia ternate, 4 to 5 parts of ginseng, 4.5 to 5.5 parts of American ginseng, 8.5 to 9.5 parts of fleece-flower root, 9 to 11 parts of Szechuan lovage rhizome, 3.5 to 4.5 parts of safflower, 3 to 4 parts of largehead atractylodes rhizome, 5.5 to 6.5 parts of Indian buead, 5 to 7 parts of Chinese angelica, 4.5 to 5.5 parts of white paeony root, 4 to 5 parts of officinal magnolia bark, 3.5 to 4.5 parts of cassia twig, 8 to 9 parts of honey-fried licorice root, 6 to 7 parts of red yeast rice, 2 to 3 parts of umbellate pore fungus, 3 to 4 parts of plantain seed and 9.

The preparation method of the oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases comprises the following steps:

the method comprises the following steps: mixing ginseng, American ginseng, polygonum multiflorum, bighead atractylodes rhizome, poria cocos, angelica sinensis, mangnolia officinalis and prepared rehmannia root in a reaction kettle, adding a proper amount of sterile water in the mixing process, and mixing for 20-30min to enable the materials to be sticky to obtain a mixture;

step two: sequentially adding pericarpium Citri Tangerinae, Notoginseng radix, rhizoma Pinelliae, ramulus Cinnamomi, Polyporus, rhizoma Ligustici Chuanxiong and radix Paeoniae alba into the above mixture, and mixing for 35-45min, continuously heating to 75-85 deg.C during mixing process, and maintaining for 8-12min to obtain further mixture;

step three: continuously adding the safflower, the honey-fried licorice root, the red yeast rice and the plantain seed into the mixture obtained in the second step, adding a proper amount of sterile water, continuously mixing after adding, heating to the temperature of 120 ℃ and 130 ℃, keeping the temperature for 10-15min, taking out, and carrying out processing treatment in different degrees according to different states and attributes of the medicines;

step four: drying the materials mixed in the steps, wherein the drying process is carried out in an aseptic state, and the drying time is 25-35min, so that the water content of the mixture is not higher than 8%;

step five: crushing the dried mixture again, and keeping the particle size of the crushed mixture to be 120 meshes, so that the mixture is convenient to brew and take orally;

step six: detecting a finished product, weighing after the finished product is detected to be qualified, independently packaging by using sterile gauze according to the dosage, and selecting a sterile environment in the packaging state to improve the safety;

step seven: and (3) packaging the gauze-wrapped traditional Chinese medicine powder again by using a glass ware to obtain the oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases, so as to avoid pollution.

The preparation method of the dried orange peel comprises the following steps:

taking 300g of orange peel, repeatedly cleaning with clear water, and draining for 3-5 min;

drying the orange peel with the drained surface at a low temperature, wherein the low-temperature drying temperature is not higher than 40-45 ℃;

airing the orange peels dried at the low temperature for a long time, and turning over the orange peels during the airing process to enable the surfaces of the orange peels to be reddish brown;

and slicing the dried orange peel for a long time and crushing for later use to obtain the required dried orange peel.

The preparation method of the honey-fried licorice root comprises the following steps:

taking 250g of liquorice, cleaning and transversely cutting into a circular sheet;

uniformly stirring and soaking the cut liquorice in honey for 3.5-4.5 hours;

turning and heating the licorice soaked in the honey until the licorice turns into a scorched state, and removing excessive water;

and (5) cooling to obtain the required honey-fried licorice root.

Example 2

Aiming at the test of the taking effect of the oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases prepared by the method, the oral traditional Chinese medicine prepared by the method is preferably selected and comprises 4 parts of dried orange peel, 3 parts of pseudo-ginseng, 3 parts of pinellia ternate, 4.5 parts of ginseng, 5 parts of American ginseng, 9 parts of fleece-flower root, 10 parts of ligusticum chuanxiong hort, 4 parts of safflower, 3.5 parts of bighead atractylodes rhizome, 6 parts of poria cocos, 6 parts of angelica sinensis, 5 parts of white paeony root, 4.5 parts of magnolia officinalis, 4 parts of cassia twig, 8.5 parts of honey-fried licorice root, 6.5 parts of red yeast rice, 2.5 parts of grifola, 3.5 parts of plantain seed and 10 parts of prepared rehmannia root, 4 groups of common cardiovascular and cerebrovascular disease medicines in a pharmacy are selected for use and compared, four control groups of A1, A2, A3 and A4 are set, E group is the cardiovascular and cerebrovascular disease preventing and treating medicines prepared by the method, 5 groups of patients with the same symptoms are respectively selected, the patients have the same, the physical condition was measured and scored from 1 month, 2 months and 3 months after the administration of the drug, and the higher the score, the better the physical condition, and the score after the administration of each group of the drug is shown in the following table.

The table one shows the body constitution score of the patients after the 5 groups of traditional Chinese medicine products are taken for different time periods:

group of	A1	A2	A3	A4	E
						1 month	6.57	6.31	5.93	7.20	7.24
2 months old	7.03	6.77	7.22	7.67	8.14
						3 months old	7.07	7.16	8.29	7.58	8.89

As can be seen from Table 1, the oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases, prepared by the method of the invention, has more remarkable curative effect on the prevention and treatment of cardiovascular and cerebrovascular diseases of patients compared with similar products sold in the market, plays a better role in inhibiting the cardiovascular and cerebrovascular diseases of patients in the early stage of taking, and has high feedback satisfaction degree after the patients take.

In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

The preferred embodiments of the invention disclosed above are intended to be illustrative only. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, to thereby enable others skilled in the art to best utilize the invention. The invention is limited only by the claims and their full scope and equivalents.

Claims (5)

1. An oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases is characterized by comprising, by weight, 3-5 parts of dried orange peel, 2-4 parts of pseudo-ginseng, 2-4 parts of pinellia ternate, 3-6 parts of ginseng, 4-6 parts of American ginseng, 8-10 parts of polygonum multiflorum, 8-12 parts of ligusticum chuanxiong hort, 3-5 parts of safflower, 2-5 parts of bighead atractylodes rhizome, 5-7 parts of poria cocos, 4-8 parts of angelica sinensis, 4-6 parts of white paeony root, 3-6 parts of mangnolia officinalis, 3-5 parts of cassia twig, 7-10 parts of honey-fried licorice root, 5-8 parts of red yeast rice, 1-4 parts of grifola, 2-5 parts of semen plantaginis and 8-12 parts of prepared rehmannia root.

2. The oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases according to claim 1, comprising, by weight, 3.5-4.5 parts of dried orange peel, 2.5-3.5 parts of pseudo-ginseng, 2.5-3.5 parts of pinellia ternate, 4-5 parts of ginseng, 4.5-5.5 parts of American ginseng, 8.5-9.5 parts of polygonum multiflorum, 9-11 parts of ligusticum chuanxiong hort, 3.5-4.5 parts of safflower, 3-4 parts of bighead atractylodes rhizome, 5.5-6.5 parts of poria cocos, 5-7 parts of angelica sinensis, 4.5-5.5 parts of radix paeoniae alba, 4-5 parts of mangnolia officinalis, 3.5-4.5 parts of cassia twig, 8-9 parts of honey-fried licorice root, 6-7 parts of red yeast rice, 2-3 parts of grifola, 3-4 parts of plantain seed and 9-11 parts of prepared rehmannia root.

3. The oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases according to claim 2, wherein the preparation method comprises the following steps:

the method comprises the following steps: mixing ginseng, American ginseng, polygonum multiflorum, bighead atractylodes rhizome, poria cocos, angelica sinensis, mangnolia officinalis and prepared rehmannia root in a reaction kettle, adding a proper amount of sterile water in the mixing process, and mixing for 20-30min to enable the materials to be sticky to obtain a mixture;

step two: sequentially adding pericarpium Citri Tangerinae, Notoginseng radix, rhizoma Pinelliae, ramulus Cinnamomi, Polyporus, rhizoma Ligustici Chuanxiong and radix Paeoniae alba into the above mixture, and mixing for 35-45min, continuously heating to 75-85 deg.C during mixing process, and maintaining for 8-12min to obtain further mixture;

step three: continuously adding the safflower, the honey-fried licorice root, the red yeast rice and the plantain seed into the mixture obtained in the second step, adding a proper amount of sterile water again, continuously mixing after adding, heating to 120 ℃ and 130 ℃, keeping the temperature for 10-15min, and taking out;

step four: drying the materials mixed in the steps, wherein the drying process is carried out in an aseptic state, and the drying time is 25-35min, so that the water content of the mixture is not higher than 8%;

step five: crushing the dried mixture again, and keeping the particle size of the crushed mixture to be 120 meshes;

step six: detecting a finished product, weighing after the finished product is detected to be qualified, independently packaging by using sterile gauze according to the dosage, and selecting a sterile environment in the packaging state;

step seven: and (4) repackaging the gauze-wrapped traditional Chinese medicine powder by using a glass ware to obtain the oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases.

4. The oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases according to claim 3, wherein the preparation method of the dried orange peel comprises the following steps:

taking 300g of orange peel, repeatedly cleaning with clear water, and draining for 3-5 min;

drying the orange peel with the drained surface at a low temperature, wherein the low-temperature drying temperature is not higher than 40-45 ℃;

airing the orange peels dried at the low temperature for a long time, and turning over the orange peels during the airing process to enable the surfaces of the orange peels to be reddish brown;

and slicing the dried orange peel for a long time and crushing for later use to obtain the required dried orange peel.

5. The oral traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases according to claim 4, wherein the preparation method of the radix Glycyrrhizae Preparata comprises:

taking 250g of liquorice, cleaning and transversely cutting into a circular sheet;

uniformly stirring and soaking the cut liquorice in honey for 3.5-4.5 hours;

turning and heating the licorice soaked in the honey until the licorice turns into a scorched state, and removing excessive water;

and (5) cooling to obtain the required honey-fried licorice root.