CN112399852A - 固体和液体恶性肿瘤中多重抗原受体t细胞对多种抗原的靶向 - Google Patents
固体和液体恶性肿瘤中多重抗原受体t细胞对多种抗原的靶向 Download PDFInfo
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- CN112399852A CN112399852A CN201980043041.XA CN201980043041A CN112399852A CN 112399852 A CN112399852 A CN 112399852A CN 201980043041 A CN201980043041 A CN 201980043041A CN 112399852 A CN112399852 A CN 112399852A
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- C07—ORGANIC CHEMISTRY
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862691486P | 2018-06-28 | 2018-06-28 | |
| US62/691,486 | 2018-06-28 | ||
| US201862697526P | 2018-07-13 | 2018-07-13 | |
| US62/697,526 | 2018-07-13 | ||
| PCT/US2019/039620 WO2020006312A1 (en) | 2018-06-28 | 2019-06-27 | Targeting of multiple antigens with multiplex car t cells in solid and liquid malignancies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112399852A true CN112399852A (zh) | 2021-02-23 |
Family
ID=68987577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980043041.XA Pending CN112399852A (zh) | 2018-06-28 | 2019-06-27 | 固体和液体恶性肿瘤中多重抗原受体t细胞对多种抗原的靶向 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12466869B2 (enExample) |
| EP (1) | EP3813863A4 (enExample) |
| JP (2) | JP2021530444A (enExample) |
| CN (1) | CN112399852A (enExample) |
| AU (1) | AU2019291882A1 (enExample) |
| WO (1) | WO2020006312A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021076197A1 (en) | 2019-10-15 | 2021-04-22 | Diverse Biotech, Inc. | Conjugate molecules |
| US20220354815A1 (en) * | 2019-11-19 | 2022-11-10 | Oklahoma Medical Research Foundation | Okn-007 as a therapeutic agent |
| KR20230104594A (ko) * | 2020-11-05 | 2023-07-10 | 유니버시티 오브 피츠버그-오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 | 자극-반응성 어댑터를 통한 범용 car t 세포의 조건부 제어 |
| AU2021397206A1 (en) * | 2020-12-08 | 2023-07-27 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Anti-egfr chimeric antigen receptors |
| US11883499B2 (en) | 2022-02-01 | 2024-01-30 | Akos Biosciences, Inc. | Cannabinoid conjugate molecules |
| US11660348B1 (en) | 2022-02-01 | 2023-05-30 | Akos Biosciences, Inc. | Cannabinoid conjugate molecules |
| WO2025085511A1 (en) * | 2023-10-18 | 2025-04-24 | University Of Washington | Systems and methods for polymer-mediated activation of engineered cells |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110288275A1 (en) * | 2001-02-12 | 2011-11-24 | Research Development Foundation | Modified Proteins, Designer Toxins, and Methods of Making Thereof |
| CN102341504A (zh) * | 2009-03-10 | 2012-02-01 | 索尼公司 | 细胞分离方法 |
| WO2015168656A2 (en) * | 2014-05-02 | 2015-11-05 | Adheren Incorporated | Biological complexes and methods for using same |
| CN105814083A (zh) * | 2013-10-15 | 2016-07-27 | 加州生物医学研究所 | 嵌合抗原受体t细胞开关和其用途 |
| WO2017143094A1 (en) * | 2016-02-16 | 2017-08-24 | Dana-Farber Cancer Institute, Inc. | Immunotherapy compositions and methods |
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| CN108660113A (zh) | 2018-05-21 | 2018-10-16 | 杭州启澜生物医学技术有限公司 | 一种制备改良型car-t细胞的方法 |
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