CN112345781B - Sample detecting system - Google Patents

Sample detecting system Download PDF

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Publication number
CN112345781B
CN112345781B CN201910731070.7A CN201910731070A CN112345781B CN 112345781 B CN112345781 B CN 112345781B CN 201910731070 A CN201910731070 A CN 201910731070A CN 112345781 B CN112345781 B CN 112345781B
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Prior art keywords
sample
analyzer
transmission
feeding mechanism
sample analyzer
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CN201910731070.7A
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CN112345781A (en
Inventor
张军伟
郁琦
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1081Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins

Abstract

The present application relates to a sample detection system comprising: at least two sample analyzers and a transmission device, wherein the transmission device comprises: the conveying mechanism comprises at least two feeding mechanisms and a plurality of sections of conveying mechanisms, wherein the sections of conveying mechanisms are sequentially connected, and a conveying channel is formed between the sections of conveying mechanisms; at least two feeding mechanisms are arranged at intervals along the transmission direction of the transmission channel, and each feeding mechanism is provided with a detection channel; each sample analyzer corresponds to one of the feed mechanisms; at least one sample analyzer is electrically connected to the corresponding feed mechanism to obtain and display fault information of the corresponding feed mechanism. Because the sample analyzer and the feeding mechanism are usually arranged adjacently, the distance is short, when the feeding mechanism fails, an operator can see the failure information on the sample analyzer nearby, so that the failure information can be found more timely and quickly.

Description

Sample detecting system
Technical Field
The present application relates to the field of medical diagnostic equipment, and in particular to a sample detection system.
Background
CRP (C-reactive protein) is an acute phase reaction protein, is normally present in a small amount in human body fluid, has different degrees of elevation in infectious diseases, and has important clinical application value. Particularly, with the rapid development of bedside rapid detection technology in recent years, CRP is widely applied to clinical infectious diseases, and becomes the focus of clinical research again.
Blood routine is one of three routine tests, and is also one of common auxiliary test means for doctors to diagnose illness; the doctor can assist in judging the physical condition by observing the change of the blood cell number and the morphological distribution. CRP has higher correlation with blood routine detection results, and CRP is often used for identifying bacterial infection and virus infection by doctors in combination with blood routine due to the characteristics of simple operation, high detection speed, small required sample amount and the like.
In the existing assembly line joint detection system, a plurality of sample analyzers are communicated through a track, each sample analyzer is connected with a main control device through an independent communication line for realizing comprehensive control, the track comprises a plurality of sections, each section of track is provided with a track controller, the track controllers are also connected into the main control device through the communication lines, and the main control device is generally a PC (personal computer) with the functions of data processing and data display.
In field application, an operator needs to operate on a PC and watch the difference between the state of the sample analyzers and the display interface in real time, but a plurality of sample analyzers are connected with the same PC, so that the distance between some sample analyzers and the PC is relatively long, and particularly when some sample analyzers are subjected to fault debugging, the operator can move between the PC and the sample analyzers for a plurality of times, which is very inconvenient.
Disclosure of Invention
To solve the above technical problems or at least partially solve the above technical problems, the present application provides a sample detection system.
A sample detection system, comprising: at least two sample analyzers and a transmission device, wherein the transmission device comprises: the device comprises at least two feeding mechanisms and a plurality of sections of transmission mechanisms, wherein the transmission mechanisms are sequentially connected, and a transmission channel for transferring a sample rack with a sample container is formed between the transmission mechanisms; at least two feeding mechanisms are arranged at intervals along the transmission direction of the transmission channel, and each feeding mechanism is provided with a detection channel;
each sample analyzer corresponds to one feeding mechanism, and the detection area of each sample analyzer corresponds to the detection channel of the corresponding feeding mechanism;
at least one sample analyzer is electrically connected to the corresponding feed mechanism to obtain and display fault information of the corresponding feed mechanism.
Optionally, each sample analyzer is electrically connected to a corresponding feeding mechanism to obtain and display fault information of the corresponding feeding mechanism.
Optionally, the at least one sample analyzer comprises a CRP analyzer for detecting C-reactive protein.
Optionally, each sample analyzer corresponds to at least one of the transport mechanisms;
the at least one sample analyzer is electrically connected with the corresponding transmission mechanism to acquire and display fault information of the transmission mechanism corresponding to the at least one sample analyzer.
Optionally, the at least one sample analyzer is electrically connected to a controller of a corresponding feeding mechanism and is electrically connected to an electrical component of the corresponding feeding mechanism through the controller, the controller being for acquiring an operating parameter with the electrical component;
the controller is further configured to determine fault information based on the operating parameters and send the fault information to the at least one sample analyzer; or the controller sends the operation parameters to the at least one sample analyzer, and the at least one sample analyzer determines fault information of a corresponding feeding mechanism according to the operation parameters.
Optionally, the at least one sample analyzer is directly electrically connected to the electrical components of the corresponding feed mechanism; the at least one sample analyzer receives an operating parameter of an electrical component connected thereto and determines fault information of a corresponding feed mechanism based on the operating parameter.
Optionally, the at least one sample analyzer further comprises: a first operation device for receiving a failure elimination operation corresponding to the failure information;
the at least one sample analyzer is further configured to generate a fault handling signal corresponding to the fault elimination operation and send the fault handling signal to a corresponding feeding mechanism and/or transmission mechanism.
Optionally, the transmission device further includes: a second operating device;
the second operation device is electrically connected with the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and is used for receiving the fault elimination operation, generating a fault processing signal corresponding to the fault elimination operation and sending the fault processing signal to the connected feeding mechanism and/or transmission mechanism.
Optionally, the transmission device further includes: a local prompter;
the local prompter is electrically connected with the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and is used for receiving fault information sent by the at least one sample analyzer and/or the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and locally prompting the fault information.
Optionally, the feeding mechanism corresponding to the at least one sample analyzer and/or the transmission mechanism corresponding to the at least one sample analyzer is initialized after receiving the fault handling signal.
Optionally, the transmission device further includes: a sample rack detector;
and the sample rack detector detects whether a sample rack exists on the initialized feeding mechanism and/or the initialized transmission mechanism, and when the sample rack detector does not detect the sample rack, the fault elimination corresponding to the fault processing signal is determined.
Optionally, the sample detection system further comprises: a transmission control device;
the transmission control device is electrically connected with the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and acquires fault information of the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer, and when the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer are faulty, the sample rack is stopped from being dispatched to the at least one sample analyzer.
Optionally, the at least one sample analyzer further comprises a first display for displaying the fault information.
Optionally, the sample detection system further comprises: a main control device, wherein,
the at least one sample analyzer is directly electrically connected with the main control device; the main control equipment is used for acquiring the operation state parameters and fault information of the at least one sample analyzer;
Alternatively, the at least one sample analyzer is indirectly electrically connected to the main control device via an intermediate data management device for managing sample data of the sample detection system.
Optionally, each sample analyzer is electrically connected to the main control device, so that the main control device obtains operation state parameters and fault information of each sample analyzer.
Optionally, the main control device includes: a second display, wherein,
the second display is used for respectively displaying the operation state parameters and fault information of each sample analyzer in different display areas,
and/or the number of the groups of groups,
the second display is used for displaying the fault information of each sample analyzer respectively in different colors.
Optionally, the at least one sample analyzer is connected to the corresponding feed mechanism by a communication link.
Optionally, the main control device is connected with the at least one sample analyzer and the transmission control device is connected with the main control device through a communication link.
Compared with the prior art, the technical scheme provided by the embodiment of the application has the following advantages:
According to the sample detection system provided by the embodiment of the application, at least one sample analyzer can be electrically connected with the corresponding feeding mechanism, so that the sample analyzer can acquire and display fault information of the corresponding feeding mechanism. Because the sample analyzer and the feeding mechanism are usually arranged adjacently, the distance is short, when the feeding mechanism fails, an operator can see the failure information on the sample analyzer nearby, so that the failure information can be found more timely and quickly.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the invention and together with the description, serve to explain the principles of the invention.
In order to more clearly illustrate the embodiments of the invention or the technical solutions of the prior art, the drawings which are used in the description of the embodiments or the prior art will be briefly described, and it will be obvious to a person skilled in the art that other drawings can be obtained from these drawings without inventive effort.
Fig. 1 is a schematic structural diagram of a sample detection system according to an embodiment of the present application;
FIG. 2 is a schematic diagram of another sample detection system according to an embodiment of the present disclosure;
FIG. 3a is a schematic diagram of a sample detection system according to an embodiment of the present disclosure;
FIG. 3b is a schematic diagram of another sample detection system according to an embodiment of the present disclosure;
fig. 4 is a schematic diagram of a display interface according to an embodiment of the present application;
FIG. 5 is a schematic structural diagram of a sample detection system according to an embodiment of the present disclosure;
FIG. 6 is a schematic structural diagram of a sample detection system according to an embodiment of the present disclosure;
FIG. 7 is a schematic structural diagram of a sample detection system according to an embodiment of the present disclosure;
FIG. 8 is a schematic structural diagram of a sample detection system according to an embodiment of the present disclosure;
FIG. 9 is a schematic structural view of a feeding mechanism of a sample analyzer according to an embodiment of the present application;
FIG. 10 is a schematic view of a loading mechanism provided by the sample detection system of the present application;
FIG. 11 is a schematic diagram of a loading buffer provided by the sample detection system of the present application;
FIG. 12 is a schematic view of a sample rack provided by the sample detection system of the present application;
FIG. 13 is a schematic diagram of a data processing apparatus according to an embodiment of the present application;
fig. 14 is a schematic structural diagram of another sample detection system according to an embodiment of the present application.
Detailed Description
For the purposes of making the objects, technical solutions and advantages of the embodiments of the present application more clear, the technical solutions of the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is apparent that the described embodiments are some embodiments of the present application, but not all embodiments. All other embodiments, which can be made by one of ordinary skill in the art without undue burden from the present disclosure, are within the scope of the present application based on the embodiments herein.
Example 1
Fig. 1 is a schematic structural diagram of a sample detection system according to an embodiment of the present application. As shown in fig. 1, the sample detection system includes: at least two sample analyzers and a transfer apparatus.
Here, at least two sample analyzers themselves may each have an internal controller.
In fig. 1, at least two sample analyzers are illustrated by way of example with a blood cell analyzer 10 and a CRP analyzer 20. Of course, in embodiments of the present application, the at least two sample analyzers may include at least two or more combinations of a blood cell analyzer, a CRP analyzer, a push-piece dyeing machine, and a saccharification instrument.
The transfer device is used for transferring the sample rack of the sample container loaded with blood, and the sample container can be transferred to any sample analyzer for detection by transferring the sample rack of the sample container loaded with blood.
Referring to fig. 1, the conveying device comprises a plurality of sections of connected conveying mechanisms (four conveying mechanisms are shown in fig. 1, and are respectively 51, 52, 53 and 54) and at least two feeding mechanisms (41 and 42), wherein the sections of conveying mechanisms (51, 52, 53 and 54) are connected end to end in sequence and are mutually connected, or gaps which do not affect the conveying of the sample rack are arranged between the adjacent conveying mechanisms. The multi-section transmission mechanism can form a transmission channel for transferring the sample rack with the sample container, and the sample container can be driven to move by the transmission mechanism in the transmission channel when the sample in the sample container is detected.
In this embodiment, as shown in fig. 1, the transmission direction in the drawing is X, two feeding mechanisms (41, 42, the whole of the dashed frame shown in 42 is a feeding mechanism) are sequentially arranged, a space is provided between any two feeding mechanisms, the size of the space can be freely set according to the place, each feeding mechanism (41, 42) is provided with a detection channel, so that a sample rack transferred on the transmission channel can be transferred to the detection channel of the feeding mechanism, and the sample rack detected in the detection channel is transferred to the transmission channel.
In particular applications, the conveyor mechanism (51, 52, 53, 54) may be any one or more of a chain type mechanism, a crawler type mechanism, a belt type mechanism, a roller type mechanism, a track type mechanism, and a multi-stage conveyor mechanism is generally the same type mechanism for the convenience of maintenance and maintenance.
In the embodiment of the present application, the transfer mechanism (51, 52, 53, 54) may be any mechanism capable of transferring the sample rack, and the shape of the transfer passage is not limited, for example: the transmission channel can be linear, can also be a broken line with a certain angle or an arc line with a certain radian, and even can be irregularly shaped.
In the embodiment of the present application, the transmission channel may be a planar channel, for example: the upper surface of the belt type mechanism is directly used as a transmission channel; in addition, the transport channel may be a semi-enclosed channel, for example, in consideration of the possibility of dropping or twisting the sample rack during transfer: the baffles are arranged on two sides of the belt type mechanism, the tops of the baffles are not closed, so that an area surrounded by the baffles is formed into a semi-enclosed transmission channel, and the sample rack is restrained by the baffles and cannot fall or twist in position. In addition, considering that the sample rack may be placed in disorder after being manually taken, the transmission channel may be a totally enclosed channel, for example: the baffles are arranged on the two sides and the top of the belt type mechanism, so that the problem of manual intervention can be avoided when the sample rack is transferred in the transmission channel.
In the embodiment of the application, the transmission channel is used as a main channel, each detection channel is used as a sub-channel, and the transmission channel is basically parallel to the detection channels. When the sample rack detection device works, the conveying mechanism can move the sample rack to the position of each feeding mechanism (41, 42) on the conveying channel, then the feeding mechanisms (41, 42) move the sample rack from the conveying channel to the corresponding detection channel, the feeding mechanisms (41, 42) drive the sample rack to move in the detection channel, and after the sample rack detection is finished, the feeding mechanisms (41, 42) can also move the sample rack from the detection channel back to the conveying channel.
One feeding mechanism may be provided for each sample analyzer, and the detection area of each sample analyzer corresponds to the detection channel of its corresponding feeding mechanism, such as the detection area of the blood cell analyzer 10 corresponds to the detection channel of the feeding mechanism 42 and the detection area of the CRP analyzer 20 corresponds to the detection channel of the feeding mechanism 41 in fig. 1. In the embodiment of the present application, the detection region corresponding to the detection channel means: the detection channel coincides with the position of the detection region, or the detection region is located in the detection channel. This ensures that the CRP analyzer 20 or the blood cell analyzer 10 can collect the sample in the sample container on the sample rack and use the collected sample for detection and analysis when the sample rack moves in the detection channel.
In the embodiment of the application, the feeding mechanism (41, 42) can also adopt any one or more of a chain type mechanism, a crawler type mechanism, a belt type mechanism, a roller type mechanism and a track type mechanism, and if a plurality of combinations are adopted, the feeding mechanism (41, 42) can be provided with a plurality of sections of mechanisms with different types. For a description of the feeding mechanism, reference is made in detail to the description of the transport mechanism described above. And will not be described in detail herein.
In the present embodiment, each sample analyzer corresponds to a feeding mechanism. In one embodiment, each sample analyzer corresponds to a respective feeding mechanism, i.e., the sample analyzer corresponds to a feeding mechanism one-to-one, as shown in FIG. 1, CRP analyzer 20 corresponds to a feeding mechanism 41, and blood cell analyzer 10 corresponds to a feeding mechanism 42. This allows the sample in the sample container on the sample rack to be subjected to CRP analysis in CRP analyzer 20 or to corresponding blood cell analysis in blood cell analyzer 10 during testing. In another embodiment, there may be multiple sample analyzers corresponding to the same feeding mechanism, for example, CRP analyzer 20 corresponds to feeding mechanism 41, and blood sample analyzer 10 and another blood sample analyzer (not shown) collectively correspond to feeding mechanism 42.
The CRP analyzer 20 is used to detect C-reactive protein of the sample in the sample container transferred by the transport mechanism to the sample rack in its corresponding detection channel. The remaining sample analyzers are used to detect other blood components than C-reactive protein of the sample in the sample container transferred by the transfer mechanism to the sample rack in its corresponding detection channel, for example: hemoglobin, WBC (white blood cells), NEUT (neutrophils), LYMPH (lymphocytes), EO (eosinophils), BASO (basophils), MONO (monocytes), and the like.
All sample analyzers can be arranged in any order in the direction of the transfer channel, as shown in fig. 1, with the blood cell analyzer 10 being located in front of the CRP analyzer 20 in the transfer direction X along the transfer channel.
In the present embodiment, "front" and "rear" are both relative concepts, wherein "front" refers to a position that passes first along the transport direction X, and "rear" refers to a position that passes after along the transport direction X, and further the blood cell analyzer 10 is located in front of the CRP analyzer 20, that is, the sample rack on the transport path passes through the blood cell analyzer 10 first and then passes through the CRP analyzer 20. Taking the direction shown in fig. 1 as an example, the transmission direction X is from right to left, then "front" refers to a position relatively to right in the drawing, and "rear" refers to a position relatively to left in the drawing, and thus, the "front" and "rear" in the present application describe the relative positional relationship between the blood cell analyzer 10 and the CRP analyzer 20, and should not be interpreted in a simple manner to literally limit the present application.
In the embodiment of the application, at least one sample analyzer is electrically connected with the corresponding feeding mechanism to acquire and display the fault information of the corresponding feeding mechanism, so that the sample analyzer electrically connected with the feeding mechanism has a fault display function, and can be subsequently called as a sample analyzer with the fault display function.
As shown in fig. 1, in the solution shown in fig. 1, the CRP analyzer 20, for example, the internal controller of the CRP analyzer 20, is electrically connected to the corresponding feeding mechanism 41, where the purpose of the electrical connection is that the CRP analyzer 20 can communicate with the feeding mechanism 41, so the electrical connection can be an electrical connection, communicating with an electrical signal; the electrical connection may also be a common communication connection, and the control command may be used to communicate, in either way, by which the CRP analyzer 20 may be caused to obtain fault information of the corresponding feeding mechanism 41, and then displayed on the CRP analyzer 20.
In an embodiment of the present application, the sample analyzer with the fault display function may include: a first display. Fault information is displayed in the first display.
The first display may be a touch screen, an LED display screen, or other screen that can display a picture.
When fault information is displayed, a fault display area fixed in the first display can be displayed, and the fault information can be displayed in a popup window mode.
According to the sample detection system provided by the embodiment of the application, at least one sample analyzer can be electrically connected with the corresponding feeding mechanism, so that the sample analyzer can acquire and display fault information of the corresponding feeding mechanism. Because the sample analyzer and the feeding mechanism are usually arranged adjacently, the distance is short, when the feeding mechanism fails, an operator can see the failure information on the sample analyzer nearby, so that the failure information can be found more timely and quickly.
Example 2
In the embodiment of the application, each sample analyzer in the detection system can be electrically connected with the corresponding feeding mechanism, so that each sample analyzer can acquire and display fault information of the corresponding feeding mechanism.
As shown in fig. 2, in addition to CRP analyzer 20 being electrically connected to feeding mechanism 41, blood cell analyzer 10 may also be electrically connected to feeding mechanism 42 such that CRP analyzer 20 may display fault information corresponding to feeding mechanism 41 and blood cell analyzer 10 may display fault information corresponding to feeding mechanism 42.
Furthermore, in embodiments of the present application, the sample analyzer is electrically connected to the corresponding feeding mechanism, and may further cause the sample analyzer to control movement of the corresponding feeding mechanism, for example: as in fig. 1, CRP analyzer 20 can control a corresponding feed mechanism 41 to move a sample rack on the transport channel to a corresponding detection channel, move the sample rack in the detection channel, and move the sample rack from the detection channel to the transport channel. Alternatively, when the blood cell analyzer 10 is electrically connected to the feeding mechanism 42, the blood cell analyzer 10 may control the feeding mechanism 42 to transfer the sample rack on the transport channel to the corresponding detection channel, move the sample rack in the detection channel, and transfer the sample rack from the detection channel to the transport channel.
In the sample detection system provided in the embodiment of the present application, the CRP analyzer 20 is electrically connected to the corresponding feeding mechanism 41, so that the CRP analyzer 20 can independently control the corresponding feeding mechanism 41 to work. Thus, for the CRP analyzer 20, the detection process of the sample rack from the transmission channel to the detection channel can be independently controlled as a relatively independent unit, no external equipment is needed to participate in control, if CRP analysis items are needed to be added in the pipeline joint detection system, the CRP analyzer 20 and the corresponding feeding mechanism 41 are directly added to the transmission channel, the control flow and equipment for the feeding mechanism 41 are not needed to be added, only the transmission mechanism in the transmission channel is needed to be maintained, and for the transmission mechanism, one more sample analyzer is added, and only the scheduling program on the transmission mechanism is needed to be adjusted.
Therefore, the sample detection system has simple control function when carrying out pipeline control, low layout cost, and is convenient and simple because the control flow of the transmission channel of the pipeline is only required to be adjusted when the sample detection system detects the CRP project according to the increase of the demand, and the original pipeline is not required to be subjected to complex transformation.
Example 3
The sample analyzer with the fault display function can be connected with a corresponding feeding mechanism, and when the sample analyzer is specifically implemented, various implementations are possible.
In one embodiment of the present application, each feed mechanism has an electrical component, particularly an electrical actuator, which may include: the electric execution part can be controlled to move so as to drive the sample rack to move. At least one sample analyzer is directly electrically connected to the electrical components of the corresponding feed mechanism; the at least one sample analyzer receives an operating parameter of an electrical component connected thereto and determines fault information of a corresponding feed mechanism based on the operating parameter.
This is considered to be that since the feeding movement of the feeding mechanism is driven by internal electrical components, in particular electrical executing components, in one embodiment of the present application, as shown in fig. 1, the CRP analyzer 20 can be directly electrically connected to the electrical components, in particular the electrical executing components, in the feeding mechanism 41. On the one hand, the electrical actuator in the feeding mechanism 41 may send the operating parameters to the CRP analyzer 20 to cause the sample analyzer to determine fault information in the feeding mechanism 41 based on the operating parameters, and on the other hand, the CRP analyzer may also control the movement of the electrical actuator by sending electrical signals to the electrical actuator to drive the movement of the feeding mechanism 41.
In another embodiment of the present application, at least one sample analyzer is electrically connected to a controller of a corresponding feeding mechanism and to an electrical component of a corresponding feeding mechanism through the controller, wherein the controller is configured to collect an operating parameter with the electrical component; the controller is further configured to determine fault information based on the operating parameters and send the fault information to the at least one sample analyzer; or the controller sends the operation parameters to the at least one sample analyzer, and the at least one sample analyzer determines fault information of a corresponding feeding mechanism according to the operation parameters.
As shown in fig. 3a, in order to achieve centralized and canonical control of the feeding mechanism 41, a controller 61 may also be provided in the feeding mechanism 41, the controller 61 being electrically connected not only to the electrical executing components, but also to the CRP analyzer 20 via a communication link (including wired and wireless communication links). In the present embodiment, the communication link may employ an RS232 link, so that, on the one hand, the controller 61 may collect the operation parameters of the electrical execution components and forward the operation parameters to the CRP analyzer 20, so that the CRP analyzer 20 determines the fault information of the feeding mechanism 41 according to the operation parameters; on the other hand, CRP analyzer 20 may send control signals directly to controller 61, with controller 61 controlling movement of the feed mechanism internal electrical executing components. In specific implementation, the controller 61 may be implemented by using an electronic device with an operational capability, such as a single-chip microcomputer or a programmable logic controller.
In other embodiments of the present application, the controller of the feeding mechanism 41 may also be integrated inside the CRP analyzer 20, for example, into an internal controller of the CRP analyzer 20, or the controller of the feeding mechanism 41 may be a separate controller provided in the feeding mechanism.
Example 4
Referring to the description in the embodiment shown in fig. 1, each of the sample analyzers corresponds to at least one of the transport mechanisms, for example: CRP analyzer 20 corresponds to transport mechanism 52 and blood cell analyzer 10 corresponds to transport mechanism 53.
In the embodiment of the application, the sample analyzer for displaying the fault information is further electrically connected with the corresponding transmission mechanism so as to acquire and display the fault information of the transmission mechanism corresponding to the at least one sample analyzer.
For example: CRP analyzer 20 is also electrically connected to transport mechanism 52, as described above with respect to the sample analyzer being electrically connected to the feed mechanism, in one embodiment of the application, the sample analyzer with fault indication may be in direct electrical connection with the electrical actuator of the transport mechanism. In another embodiment of the present application, the sample analyzer with fault display function can be electrically connected to both the corresponding feeding mechanism and the electrical executing components in the transmission mechanism at the same time by the controller, and as shown in fig. 3b, the CRP analyzer 20 can be electrically connected to the electrical executing components in the feeding mechanism 41 and the electrical executing components in the transmission mechanism 52 at the same time by the controller 61.
In other embodiments, the controller 61 may be shared with other mechanisms in addition to the feeding mechanism 41 and the conveying mechanism 52, such as: the feeding mechanism 42 and the conveying mechanism 53 are shared, and the like. In any case, the CRP analyzer can acquire fault information of the feeding mechanism and/or the transmission mechanism, so specific connection relation and control relation between the CRP analyzer and the corresponding feeding mechanism and/or the transmission mechanism are not limited in the application.
Example 5
The sample detection system provided by the foregoing may enable the sample analyzer to acquire and display the fault information of the corresponding feeding mechanism, but in practical application of the sample analyzer, when a fault occurs, the fault needs to be processed.
For this reason, in the embodiment of the present application, a scenario is as follows: the sample analyzer with the fault display function is further used for generating a fault processing signal corresponding to the fault elimination operation and sending the fault processing signal to any one or both of a corresponding feeding mechanism and a corresponding transmission mechanism so as to process faults of the feeding mechanism or the transmission mechanism with faults.
In the above scenario, the sample analyzer may be provided with fault handling policy information, and once the fault information is determined, the corresponding fault handling policy may be searched, and a fault handling signal may be generated, so that fault handling may be automatically performed. The fault handling policy information may be a database or a fault handling table.
In another scenario, the sample analyzer with fault display function further comprises: a first operation device for receiving a failure elimination operation corresponding to the failure information; the sample analyzer with the fault display function is also used for generating a fault processing signal corresponding to the fault elimination operation and sending the fault processing signal to a corresponding feeding mechanism.
The first operating device may be a common input device, such as: touch screen, keyboard, mouse, rocker or electric control button etc., when the first operation equipment adopts the touch screen, the first operation equipment is the virtual button on the touch screen. The fault-elimination operation may be a virtual key operation, for example: the virtual buttons displayed on the touch screen or the display screen can be controlled by clicking the virtual buttons on the touch screen or clicking the virtual buttons on the display screen by using a keyboard and a mouse, and can also be physical keys, for example: and the rocker or the electric control button is operated to directly generate a control electric signal.
When the method is applied specifically, an operator can directly input fault elimination operation by using the first operation equipment according to actual fault information. In addition, in other embodiments of the present application, when the fault information is displayed, the fault handling policy corresponding to the fault information may also be displayed at the same time, so that the operator may input the fault removal operation according to the fault handling policy.
When the fault information is displayed in the fault display area, if the fault information area is clicked, a pop-up window corresponding to the fault information may also be displayed in a pop-up window form, as shown in fig. 4, and fig. 4 illustrates a touch screen as an example, where fig. 4 includes: a first display 201, a pop-up window 202, a fault display area 203, a help display area 204, and operation buttons 205. In the failure display area, 3 failure names corresponding to the failure information are displayed, and when the 1 st failure name is clicked, the failure processing policy corresponding to the 1 st failure name is displayed in the help display area 204.
The operation button 205 is used to facilitate the operator to operate according to the fault name, and the operator in fig. 4 clicks the "cancel fault" button displayed on the touch screen, and the sample analyzer will automatically cancel the fault that is currently possible to cancel. For faults which cannot be automatically eliminated, operators can perform corresponding fault treatment according to the fault help information. The operator clicks the "eliminate alarm" button, which eliminates the alarm of the host. The operator clicks the "close" button to close the fault dialog, but the fault information area on the interface will display the corresponding fault information. If the trouble information area is clicked again, the trouble dialog may be opened again.
In other embodiments of the present application, the fault handling strategy may also be seen in table 1 below.
TABLE 1
Example 6
In the foregoing embodiment 5, the first operation device is provided on the sample analyzer with the fault display function so as to be operated by an operator, and in this embodiment, the transmission device may be further provided with: and a second operating device.
The second operating device may be provided on the transport mechanism or on the feeding mechanism.
The second operation device is electrically connected with any one or two of a feeding mechanism and a transmission mechanism corresponding to the sample analyzer with the fault display function, and is used for receiving the fault elimination operation, generating a fault processing signal corresponding to the fault elimination operation and sending the fault processing signal to any one or two of the connected feeding mechanism and transmission mechanism.
The second operating device may be a common input device, such as: touch screens, keyboards, mice, rockers, or electrically controlled buttons, etc. The fault-elimination operation may be a virtual key operation, for example: the virtual buttons displayed on the touch screen or the display screen can be controlled by clicking the virtual buttons on the touch screen or clicking the virtual buttons on the display screen by using a keyboard and a mouse, and can also be physical keys, for example: and the rocker or the electric control button is operated to directly generate a control electric signal.
Example 7
For all the foregoing embodiments, the fault display of the feeding mechanism is in the sample analyzer with the fault display function, and in practical application, in order to facilitate the operator to more intuitively understand the location of the fault, in this embodiment of the present application, the transmission device may further include: a local prompter.
The local prompter is electrically connected with any one or two of a feeding mechanism and a transmission mechanism corresponding to the sample analyzer with the fault display function and is used for receiving fault information sent by the sample analyzer with the fault display function or fault information sent by any one or two of the feeding mechanism and the transmission mechanism corresponding to the sample analyzer with the display function and locally prompting.
The local cue is typically provided on or beside the feeding or transport mechanism of the transport device. Therefore, when the local prompter prompts, the fault position can be indicated.
In the embodiment of the present application, the local prompter may be a common alarm of sound, light, electricity, etc., for example: the LED indicator lamp, the loudspeaker, the display screen and the like can also be other mechanical movement equipment controlled by the electric signal, and the prompt is carried out through the movement of the mechanical movement equipment.
Example 8
In all the foregoing embodiments, the acquisition and display of faults are described, and in embodiments of the present application, the system may also handle faults when a feed mechanism or transport mechanism fails.
For this reason, in the embodiment of the present application, any one or both of the feeding mechanism and the conveying mechanism corresponding to the sample analyzer with the fault handling function is initialized after receiving the fault handling signal.
Initialization is one of the most common operations of fault handling, and in other embodiments of the present application, after the feeding mechanism or the transmission mechanism receives the fault handling signal, operations corresponding to the fault handling signal may also be performed, for example: reset, etc.
In practical application, after initialization, it is further required to determine whether there is a residual sample rack on the feeding mechanism or the conveying mechanism, and if there is still a residual sample rack, since the residual sample rack cannot be scheduled, it is determined that the initial failure has not been eliminated. Failure elimination is only determined if there are no remaining sample holders on the feeding mechanism or the transport mechanism after initialization.
For this reason, in the embodiment of the present application, the transmission apparatus further includes: a sample rack detector; and when the sample rack detector does not detect the sample rack, determining fault elimination corresponding to the fault processing signal.
The sample rack detector may be a camera, a sensor having a shielding detection function such as a photoelectric gate, or a pressure sensor, etc., and it is possible to detect whether or not a sample rack is present in a specific area (an area corresponding to the transport mechanism distribution mechanism) by the sample detector.
Example 9
FIG. 5 is a schematic diagram of another embodiment provided by the sample detection system of the present application.
As shown in fig. 5, the difference from the previous embodiment is that: the sample detection system further comprises: and a main control device 30.
In the present embodiment, at least one sample analyzer (including the CRP analyzer 20 and the blood cell analyzer 10 here), particularly all sample analyzers, are electrically connected to the main control device 30, and the main control device 30 is added for the purpose of collecting detection result data and instrument status data of the sample analyzers and performing centralized management and display, wherein the instrument status data includes fault information.
In a specific application, for CRP analyzers and all sample analyzers which are jointly detected on a production line, the detection results of the CRP analyzers and all sample analyzers need to be summarized together, so that an inspector can quickly know fault information and/or detection results of all analyzers.
In the embodiment of the present application, the main control device 30 may also be directly electrically connected to at least one sample analyzer, such as the CRP analyzer 20, for example, an internal controller thereof, and in one scenario, the main control device 30 may be connected to at least one sample analyzer, such as the CRP analyzer 20, through a communication network (such as ethernet) so that the at least one sample analyzer, such as the CRP analyzer 20, reports the detection result as well as the instrument status data.
For the pipeline detection system, an intermediate data management device for data management and interaction may be further provided, and in another embodiment of the present application, as shown in fig. 6, the diagram includes: the router 31 and the intermediate data management device 32, the crp analyzer 20 is connected with the intermediate data management device 32 through a network, the intermediate data management device 32 is connected with the router 31 through the network, the main control device 30 is also connected with the intermediate data management device 32 through the router 31, so that the crp analyzer 20 can send data into the main control device 30 through the intermediate data management device 32.
In the embodiment of the present application, the intermediate data management device 32 is used for managing data of the sample detection system, including detection data of the sample analyzer, status data of the sample conveying device, sample data, and the like. The intermediate data management device 32 may have information inquiry, data presentation, results auditing, results transmission, report printing, etc. The information query may query a Laboratory Information System (LIS) for patient-related information. The result auditing can be performed manually or automatically, and the measurement mode can be increased or decreased by rules, so that the result auditing can be performed on the sample analyzer.
In the embodiment of the present application, the intermediate data management device 32 may be in a software form, or be a hardware integrated chip or the like. The intermediate data management device 32 may be provided on an instrument in the sample detection system (e.g. the blood cell analyzer 10 or the main control device 30) or may be provided on other terminal devices. In this embodiment, a sample analyzer, such as the blood cell analyzer 10 or the CRP analyzer 20, may send its operating state parameters and/or fault information and/or test data to the intermediate data management device 32 and be displayed on the equipment in which the intermediate data management device 32 is installed.
In another embodiment of the present application, a main control device includes: and the second display is used for respectively displaying the operation state parameters and the fault information of each sample analyzer in different display areas in one scene. The data of different sample analyzers are different in display areas on the second display, so that an operator can quickly and conveniently know the operation state parameters and fault information of each sample analyzer through the second display,
in another scenario, the second display is configured to display the fault information of each sample analyzer in different colors.
The fault information is displayed through different colors, and after an operator is skilled in mastering the corresponding relation between the colors and the fault information, the operator can quickly and intuitively know the current fault information through the colors and further watch the details of the fault information displayed in the second display in detail.
In a specific application, the fault information is uniformly displayed in the fault display area, and then the fault display area can use different colors to represent different fault information or different colors to represent the fault information of different sample analyzers.
In one embodiment of the present application, the background colors used in the fault information area may be red, orange, blue and green in this order, depending on the fault level from high to low.
Red: representing a fault that is fatal. Upon such failure, the current action should be terminated immediately and any action is prohibited.
Orange: representing a fault that is a disabled stage. The current action should be terminated immediately after such a fault occurs.
Blue: the representation is a fault of the limiting stage. After such a failure, the current operation may continue to be performed, but other operations associated with such a failure are restricted.
Green: the representation is a fault at the hint level. After such a failure, the current operation may continue to be performed without any restriction.
Example 10
As shown in fig. 7, for another embodiment provided in the present application, the sample detection system provided in this embodiment may further include: a transmission control device 90.
The transmission control device is electrically connected with the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and acquires fault information of the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer, and when the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer are faulty, the sample rack is stopped from being dispatched to the at least one sample analyzer.
The transport control device 90 functions to schedule the sample rack to be moved in the transport path and the detection path and can be moved to a position corresponding to any one of the feed mechanisms in the transport path to facilitate feeding the sample rack into a CRP analyzer or other sample analyzer for detection. In the embodiment of the present application, the transmission control device 90 may use an electronic device with an arithmetic capability, such as a single-chip microcomputer or a programmable logic controller. In addition, the transmission control device 90 and each transmission mechanism may be communicatively connected via a CAN bus.
In a specific application, each transmission mechanism may be separately provided with a controller, or multiple transmission mechanisms may share a controller, as shown in fig. 7, where 62 is a controller, and 62 is shared by multiple transmission mechanisms, and the controller 62 is connected to an electrical component in the transmission mechanism and used for controlling the motion of the transmission mechanism, and the controller 62 may be a single-chip microcomputer or a programmable logic controller.
The transmission control device 90 may also be electrically connected to the main control device 30 through a communication network, as shown in fig. 5, and the transmission control device 90 is connected to the main control device 30 through a router 31 to acquire the acquired instrument status data of the sample analyzer from the main control device 30 for sample rack scheduling.
In the pipeline joint detection process, the sample rack flows among different sample analyzers, so that the operation of the sample rack in a transmission channel and a detection channel is better controlled, the problem of channel blockage caused by long-time waiting is avoided, the current working state of the sample analyzer needs to be mastered, the sample rack can be reasonably scheduled according to the current working state of the sample analyzer, such as fault information, the optimal condition is that the sample rack is in an idle state when the sample rack is scheduled to the detection channel corresponding to the CRP analyzer, the blood sample in a sample container on the sample rack can be directly detected, and the sample rack can be stopped from being scheduled to the CRP analyzer when the CRP analyzer is in fault.
Since the dispatching needs not only the transmission mechanism but also the feeding mechanism for cooperation, in the embodiment of the present application, the transmission control device 90 is also connected with the CRP analyzer 20, and as shown in fig. 7, the transmission control device 90 is indirectly connected with the CRP analyzer 20 through the controller 61, so that the transmission control device 90 can send the dispatching information to the CRP analyzer 20. For example, when a sample rack is dispatched to the location of transport mechanism 52, transport control device 90 needs to send a get-in message to CRP analyzer 20 so that CRP analyzer 20 can control feed mechanism 41 to remove the sample rack from the transport path of transport mechanism 52 and move to the detection path of feed mechanism 41.
The system is provided in this embodiment, for the CRP analyzer 20, the scheduling situation can be obtained from the transmission control device 90, when the in-place message is received, the feeding mechanism 41 is controlled to move the sample rack out of the transmission channel, and for the feeding mechanism, the CRP analyzer can be completely independently controlled, and no external device (such as a main control device) is needed to participate.
Example 11
In this embodiment of the present application, the feeding mechanism corresponding to the CRP analyzer 20 may be controlled by the CRP analyzer alone, and for the feeding mechanisms of the remaining sample analyzers, the sample analyzers may also be used for controlling alone, where the scheduling control logic used is: the main control device sends instrument state information to the transmission control device, the transmission control device performs scheduling according to the instrument state information and detection required to be performed, the transmission mechanism is directly controlled during scheduling, and the corresponding feeding mechanism is controlled through the CRP analyzer.
Also, in this embodiment, each of the sample analyzers is electrically connected to a respective corresponding feeding mechanism, and each of the sample analyzers is configured to control the corresponding feeding mechanism to remove a sample rack from the transport channel and to transfer the sample rack to a corresponding detection channel, to move the sample rack in the detection channel, and to transfer the sample rack from the detection channel to the transport channel. As shown in fig. 7, the blood cell analyzer 10 is shown coupled to a feed mechanism 42.
This requires that each sample analyzer accurately knows whether a sample rack is scheduled in place on the transport channel, for which purpose, in one embodiment of the present application, a transport control device may be electrically connected to each sample analyzer for sending a message to the corresponding sample analyzer when the sample rack is moved to a corresponding position in the transport channel for the sample analyzer to control the corresponding feeding mechanism to move the sample rack out of the transport channel.
Example 12
The feed mechanism for the CRP analyzer or other sample analyzer described above employs the same scheduling logic, i.e. is controlled by the CRP analyzer or other sample analyzer described above itself, but for existing sample analyzers, it may not have a control design of the feed mechanism inside, whether hardware or software, for which purpose the main control device may be electrically connected to the feed mechanism for each sample analyzer for controlling the corresponding feed mechanism for moving the corresponding sample rack to the corresponding detection channel, moving the sample rack in the detection channel and moving the sample rack out of the detection channel in order to control the feed mechanism for these sample analyzers. In a specific application, as shown in fig. 8, the transmission control device 90 may also be connected to the main control device 30 through the router 31, and the main control device 30 is directly connected to the feeding mechanism 42.
Thus, when the transfer control device schedules the sample rack transfer, if the sample rack in the transfer channel is in place in the corresponding feeding mechanism 42 of the blood cell analyzer 20 (i.e., the sample rack on the transfer channel is transferred to the position of the feeding mechanism 42 of the blood cell analyzer 20), the transfer control device 90 may send a message of in place to the main control device 30 via the communication line, and the main control device 30 further controls the feeding mechanism 42 to perform movement.
In other embodiments, when the feed mechanism 42 and the transmission mechanism 53 share a controller communicatively coupled to the transmission control device 90, the transmission control device 90 may also send a message to the controller directly to control the movement of the feed mechanism 42.
Example 13
Referring to fig. 9, a detailed result diagram of the feeding mechanism according to the embodiment of the present application is shown. The dashed box in fig. 9 shows the in-place position of the transport channel up to the sample rack of CRP analyzer 20.
As shown in fig. 9, the feeding mechanism 41 corresponding to the CRP analyzer in the drawing may include: the drive mechanism 421, load buffer 422 and load mechanism 423, wherein:
the transmission mechanism 421 can be any one or more of a chain type mechanism, a crawler type mechanism, a belt type mechanism, a roller type mechanism and a track type mechanism, and if a plurality of combinations are adopted, the transmission mechanism 421 can be provided with a plurality of sections of mechanisms with different types. In the embodiment of the present application, the transmission mechanism 421 has a detection passage formed therein. And the position of the detection channel corresponds to the position of the detection area of the CRP analyzer 20 corresponding to the feeding mechanism, so that the sample container transferred in the detection channel can be detected smoothly.
As shown in fig. 9, the loading buffer 422 is located between the detection channel and the transmission channel, and the loading buffer 422 mainly considers that if the number of sample frames transferred from the transmission channel to the analyzer is large, and the sample analyzer needs to consume a certain amount of time for completing each sample frame, if all the sample frames on the transmission channel are transferred to the sample analyzer, normal analysis and detection will be affected, and the loading buffer 422 is set, so that the sample frames transferred from the transmission channel are buffered in the region first, and then the sample frames buffered in the region are sequentially transferred to the detection channel according to the detection speed of the analyzer.
As shown in fig. 9, the loading mechanism 423 is located below the loading buffer 422, and is configured to transfer the sample rack passing through the transmission channel to the loading buffer 422, and transfer the sample rack of the loading buffer 422 to the detection channel. When the sample rack is moved to the in-place position shown by the dashed box in fig. 9, the loading mechanism 423 ejects the sample on the transport path out of the transport path.
In this embodiment of the application, the loading mechanism has two functions, namely, unloading the sample rack from the transmission channel and transferring the sample rack loaded in the buffer area to the detection channel, so that the transmission control device needs to send the in-place message of the sample rack to the CRP analyzer, so that the CRP analyzer can control the loading mechanism to unload the sample rack from the transmission channel.
In an embodiment of the present application, as shown in fig. 10, the loading mechanism 423 may include: a bracket 131, a pusher jaw 132, and a pusher jaw driving device 133, the bracket 131 being disposed between the transmission path and the detection path for supporting the loading mechanism 423; the pushing claw 132 is arranged on the bracket 131 and is used for driving the sample rack stored in the loading buffer area to slide towards the direction of the detection channel or the transmission channel, so that the sample rack is transmitted between the transmission channel and the detection channel; the pawl driving device 133 is disposed on the bracket 131, and is used for driving the pawl 132 to perform the above-mentioned movement process.
In an alternative embodiment, as shown in fig. 11, the loading buffer 422 in the sample detection system according to the embodiment of the present application includes: the panel 141, wherein the panel 141 is used for carrying a sample rack, and a long hole 142 extending from a transmission channel to a detection channel is formed in the panel 141. The pawl driving device 133 includes: the horizontal pushing assembly 1331, the pushing claw mounting seat 1332 and the lifting assembly 1333, wherein the horizontal pushing assembly 1331 is arranged on the bracket 131 and can horizontally move relative to the bracket 131; the pushing claw mounting seat 1332 is linked with the horizontal pushing assembly 1331, and the horizontal pushing assembly 1331 drives the pushing claw mounting seat 1332 to horizontally move between the detection channel and the transmission channel; the lifting assembly 1333 is disposed on the pawl mounting seat 1332, the pawl 132 is disposed on the lifting assembly 1333, and the lifting assembly 1333 drives the pawl 132 to rise, so that the pawl 132 at least partially penetrates through the long hole 142 on the panel 141 and is matched with the bottom of the sample rack, and the horizontal pushing assembly 1331 can drive the pawl mounting seat 1332 to perform horizontal movement, so that the pawl 132 drives the sample rack to slide on the panel 141 towards the detection channel or the transmission channel. Optionally, in order to locate the moving position of the pawl 132, a position sensor 135 is disposed at the two ends of the bracket 131 near the detection channel and the transmission channel, and the position sensor 135 can cooperate with the pawl mounting seat 1332 or the pawl 132 to enable the system controller to obtain the moving position of the pawl 132. The position sensor 135 is preferably an optocoupler, and an optocoupler piece is disposed on the pawl mount 1332, and when the pawl mount 1332 moves to approach the detection channel or the transmission channel, the optocoupler piece acts with the optocoupler to enable the optocoupler to send out an induction signal, so that the system controller can determine the position of the pawl 132.
In an alternative embodiment of the present application, the horizontal pushing component 1331 may be a motor synchronous belt driving mechanism, and the motor is used to drive the synchronous belt to rotate, so as to drive the pushing claw mounting seat 1332 to perform horizontal movement. Of course, the horizontal pushing component 1331 may also be a linear motor, and the primary driving pawl mounting seat 1332 of the linear motor performs horizontal linear motion. In order to ensure stable operation of the pawl mount 1332, a linear guide rail may be mounted on the bracket 131, and the pawl mount 1332 may be slidably mounted on the linear guide rail. The lifting component 1333 can be a lifting cylinder, the cylinder body of the lifting cylinder is fixed on the pawl mounting seat 1332, the pawl 132 is fixedly connected to the piston rod of the lifting cylinder, and the piston rod of the lifting cylinder is controlled to drive the pawl 132 to move in a lifting manner.
As shown in fig. 12, the bottom of the sample rack 15 is provided with bottom grooves 151 at intervals, and when the pushing claw 132 protrudes upward from the long hole 142 on the panel 141, it can be inserted into the bottom grooves 151 at the bottom of the sample rack 15, thereby driving the sample rack 15 to move synchronously. As can be seen from the figure, a plurality of detection bits 152 are provided on the sample holder 15.
Before the sample rack 15 shown in fig. 12 enters the analyzer to perform sampling analysis, the analyzer needs to scan the bar code of the sample container on the sample rack 15 to obtain a sampling analysis task of the corresponding sample, so that the side wall of the sample rack 15 corresponding to each detection position is provided with a scanning hole 153, so that the scanner can scan the container identifier stuck on the sample container.
In an alternative embodiment, as shown in fig. 9, the feeding mechanism further includes: the unloading buffer zone 424 and the unloading mechanism 425, wherein the unloading buffer zone 424 is located between the detection channel and the transmission channel, and the unloading buffer zone 424 and the loading buffer zone 422 are arranged at intervals along the transmission direction of the detection channel, as shown in fig. 9, the loading buffer zone 422 and the unloading buffer zone 424 are respectively located at two ends of the detection channel; the unloading mechanism 425 is located in the unloading buffer area and is used for transferring the sample rack passing through the detection channel to the unloading buffer area 424 and transferring the sample rack of the unloading buffer area 424 to the transmission channel.
In the embodiment of the present application, the detailed structure of the unloading mechanism may be referred to the foregoing description of the loading mechanism, and will not be repeated herein.
Example 14
In other embodiments of the present application, the loading mechanism may be only responsible for moving the sample rack of the loading buffer to the detection channel, and not for moving the sample rack out of the transfer channel, and for this purpose, in embodiments of the present application, the transfer mechanism may further include: at least one dispensing mechanism. The dispensing means can be configured, for example, as a push rod for pushing the sample rack on the transport channel onto the loading buffer.
Each distributing mechanism corresponds to one feeding mechanism, in particular to a loading buffer zone of the feeding mechanism, and the transmission control equipment is used for controlling the corresponding distributing mechanism to move out the sample rack on the transmission channel when the sample rack is moved to a corresponding position of any sample analyzer in the transmission channel.
In this case, the transport mechanism can directly transfer the sample rack to the loading buffer of any one of the feeding mechanisms at the time of dispatch without notifying the sample analyzer.
Accordingly, for the feeding mechanism, details of the scheduling cannot be known without an in-place message, and for this purpose, in the embodiment of the present application, the feeding mechanism may further include: the sample rack detector is arranged in the loading buffer area and is used for sending a starting signal when detecting that the sample rack is buffered in the loading buffer area;
the loading mechanism is electrically connected with the sample rack detector and is used for transferring the sample rack in the loading buffer area to a corresponding detection channel after receiving a starting signal sent by the sample rack detector.
In this embodiment of the present application, the sample rack detector may be a camera, or may be a sensor having a shielding detection function, such as a photoelectric gate, or may be a pressure sensor, or may be another sensor, where whether a sample rack is present in a specific area (an area corresponding to the delivery mechanism of the delivery mechanism) may be monitored by the sample detector, and once the sample rack is detected, the sample rack may be indicated as being in place, and may be transferred from the loading buffer area to the detection channel.
The structures of the internal controllers, the controllers 61, 62, the main control device 30, and the transmission control device 90 of the sample analyzer (e.g., CRP analyzer 20) mentioned in the above embodiments are described in detail, and referring to fig. 13, a schematic structural diagram of a data processing device according to an embodiment of the present application is provided.
The data processing device 110 comprises at least: the processing component 111, RAM112, ROM113, communication interface 114, memory 116, and I/O interface 115, where the processing component 111, RAM112, ROM113, communication interface 114, memory 116, and I/O interface 115 communicate via bus 117.
The processing component may be a CPU, GPU or other chip with computing capabilities.
The memory 116 stores various computer programs such as an operating system and application programs for execution by the processor element 111 and data required for execution of the computer programs. In addition, during sample detection, data stored locally may be stored in memory 116, if desired.
The I/O interface 115 is constituted by a serial interface such as USB, IEEE1394, or RS-232C, a parallel interface such as SCSI, IDE, or IEEE1284, and an analog signal interface composed of a D/a converter, an a/D converter, and the like. An input device, such as a keyboard, mouse, touch screen, or other control buttons, is connected to the I/O interface 115, and a user may directly input data to the data processing device 110 using the input device. In addition, a display having a display function, for example, may be connected to the I/O interface 115: a liquid crystal screen, touch screen, LED display screen, etc., the data processing device 110 may output the processed data as image display data to a display for display, for example: analytical data, instrument operating parameters, etc.
The communication interface 114 is an interface that may be any communication protocol known at present. The communication interface 114 communicates with the outside through a network. The data processing device 110 may communicate data with any of the devices connected via the network via the communication interface 114 in a communication protocol.
In the embodiment of the present application, the internal controllers, the controllers 61, 62, the main control device 30 and the transmission control device 90 of the sample analyzer may employ the structure of the data processing device 110 described above, and in addition, the data processing device 110 described above may retain only the components of the operation data and the communication interface, such as the I/O interface, in consideration of the fact that the controllers 61, 62 or the transmission control device 90 do not require a strong computing power.
Fig. 14 is an implementation scenario diagram of a sample detection system according to an embodiment of the present application.
Referring to fig. 14, a plurality of sample analyzers are included: the blood cell analyzer 10, the CRP analyzer 20, the patch staining machine 50, and the saccharification instrument 60 are disposed sequentially from the beginning to the end in the transport direction X along the transport path.
As shown in fig. 14, the sample detection system may further include: a loading platform 70 and a platform loading mechanism 71, wherein the loading platform 70 is positioned at one end of the transfer channel, and the loading platform 70 is used for placing the sample rack. In the embodiment of the present application, the loading platform 70 is located at the front end of the transport direction X of the transport channel, that is, the sample rack moves from the loading platform 70 into the transport channel, and then is transported to each analyzer through the transport channel. The stage loading mechanism 71 is used to transfer the sample rack on the loading stage 70 to the transport path.
In addition, in an embodiment of the present application, the sample detection system further includes: a sample rack detector (not shown) disposed on the loading platform 70 for detecting the sample rack on the loading platform 70, and transmitting a transfer signal when the sample rack detector detects the sample rack on the loading platform 70. The flatbed loading mechanism 71 is electrically connected to the sample rack detector, and when the flatbed loading mechanism 71 receives a transfer signal, the flatbed loading mechanism 71 transfers the sample rack from the loading platform 70 to the transfer path.
As shown in fig. 14, in an embodiment of the present application, the sample detection system further includes: an unloading platform 80 and a platform unloading mechanism 81, wherein the unloading platform 80 is arranged at the other end of the transmission channel, and the unloading platform 80 is used for placing a sample rack of the sample rack. As shown in embodiment 12, the unloading platform 80 is provided at the end of the transport direction X of the transport path. When all samples in the sample containers on the sample rack on the transfer channel are detected, the sample rack is transferred to the unloading platform 80 for storage. The platform unloading mechanism 81 is used to transfer the sample rack in the transport path to the unloading platform 80.
Referring to fig. 14, in which the feeding mechanisms of the blood cell analyzer 10, the CRP analyzer 20, the push-piece dyeing machine 50 and the saccharification instrument 60 are respectively provided with one controller 61, all the controllers 61 are connected with the transmission control device 90. In addition, the CRP analyzer 20 is directly connected to its corresponding controller 61, and the controllers 61 corresponding to the blood cell analyzer 10, the push-piece dyeing machine 50, and the saccharification instrument 60 are all connected to the main control device 30. The platform loading mechanism and the platform unloading mechanism are respectively provided with a controller 61.
In fig. 14, the multi-stage transmission mechanism shares one controller 62, and the controller 62 is also connected to a transmission control device 90. Of course, in other embodiments, the multi-stage transport mechanism may have a separate controller or the multi-stage transport mechanism may share one controller 61 with the corresponding feed mechanism.
Through the above-mentioned connection scheme, on the one hand, the blood cell analyzer 10, the CRP analyzer 20, the push-piece dyeing machine 50 and the saccharification instrument 60 can obtain the fault information of the feeding mechanism corresponding to each through the control 61, and obtain the fault information of the transmission mechanism corresponding to each through the control 62 and display the fault information respectively, so that the fault information is displayed locally, and the operator can know the fault information quickly and conveniently in a short distance.
On the other hand, the CRP analyzer 20 controls the feeding mechanism corresponding to the CRP analyzer 20 through the corresponding controller 61. In addition, the main control device 30 controls the feeding mechanisms corresponding to the blood cell analyzer 10, the push-piece dyeing machine 50, and the saccharification instrument 60, respectively, through the corresponding controllers 61. Further, the transport control device 90 controls the deck loading mechanism 71 and the deck unloading mechanism 81 through the corresponding controllers 61. Thus, the transport control device 90 can perform a rational dispatch control of the sample rack in the transport path and in each feeding mechanism when the operation state of each instrument is acquired by the router 31.
It should be noted that in this document, relational terms such as "first" and "second" and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.
The foregoing is only a specific embodiment of the invention to enable those skilled in the art to understand or practice the invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (17)

1. A sample detection system, comprising: at least two sample analyzers and a transfer apparatus, wherein,
the transmission apparatus includes: the device comprises at least two feeding mechanisms and a plurality of sections of transmission mechanisms, wherein the transmission mechanisms are sequentially connected, and a transmission channel for transferring a sample rack with a sample container is formed between the transmission mechanisms; at least two feeding mechanisms are arranged at intervals along the transmission direction of the transmission channel, and each feeding mechanism is provided with a detection channel;
each sample analyzer corresponds to one feeding mechanism, and the detection area of each sample analyzer corresponds to the detection channel of the corresponding feeding mechanism; the sample analyzer and the corresponding feeding mechanism are adjacently arranged;
at least one sample analyzer is electrically connected with the corresponding feeding mechanism to acquire and display fault information of the corresponding feeding mechanism; the at least one sample analyzer further comprises: a first operation device for receiving a failure elimination operation corresponding to the failure information; the at least one sample analyzer is further configured to generate a fault handling signal corresponding to the fault elimination operation and send the fault handling signal to a corresponding feeding mechanism and/or transmission mechanism.
2. The sample testing system of claim 1, wherein each of said sample analyzers is electrically connected to a corresponding feed mechanism to obtain and display fault information for the corresponding feed mechanism.
3. The sample detection system of claim 1 or 2, wherein the at least one sample analyzer comprises a CRP analyzer for detecting C-reactive protein.
4. The sample detection system of claim 1, wherein each of said sample analyzers corresponds to at least one of said transport mechanisms;
at least one sample analyzer is electrically connected to the corresponding transport mechanism to obtain and display fault information of the transport mechanism corresponding to the at least one sample analyzer.
5. The sample detection system of claim 1, wherein the at least one sample analyzer is electrically connected to and through a controller of a corresponding feed mechanism for acquiring an operating parameter of the electrical component;
the controller is further configured to determine fault information based on the operating parameters and send the fault information to the at least one sample analyzer; or the controller sends the operation parameters to the at least one sample analyzer, and the at least one sample analyzer determines fault information of a corresponding feeding mechanism according to the operation parameters.
6. The sample detection system of claim 5, wherein the at least one sample analyzer is directly electrically connected to the electrical components of the corresponding feed mechanism; the at least one sample analyzer receives an operating parameter of an electrical component connected thereto and determines fault information of a corresponding feed mechanism based on the operating parameter.
7. The sample detection system of claim 4, wherein the transmission device further comprises: a second operating device;
the second operation device is electrically connected with the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and is used for receiving the fault elimination operation, generating a fault processing signal corresponding to the fault elimination operation and sending the fault processing signal to the connected feeding mechanism and/or transmission mechanism.
8. The sample detection system of claim 4, wherein the transmission device further comprises: a local prompter;
the local prompter is electrically connected with the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and is used for receiving fault information sent by the at least one sample analyzer and/or the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and locally prompting the fault information.
9. The sample detection system of claim 7, wherein the feed mechanism corresponding to the at least one sample analyzer and/or the transport mechanism corresponding to the at least one sample analyzer is initialized upon receipt of the fault handling signal.
10. The sample detection system of claim 9, wherein the transmission device further comprises: a sample rack detector;
and the sample rack detector detects whether a sample rack exists on the initialized feeding mechanism and/or the initialized transmission mechanism, and when the sample rack detector does not detect the sample rack, the fault elimination corresponding to the fault processing signal is determined.
11. The sample detection system of claim 4, further comprising: a transmission control device;
the transmission control device is electrically connected with the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and acquires fault information of the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer, and when the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer are faulty, the sample rack is stopped from being dispatched to the at least one sample analyzer.
12. The sample detection system of claim 1, wherein the at least one sample analyzer further comprises a first display for displaying the fault information.
13. The sample detection system of claim 11, further comprising: a main control device, wherein,
the at least one sample analyzer is directly electrically connected with the main control device; the main control equipment is used for acquiring the operation state parameters and fault information of the at least one sample analyzer;
alternatively, the at least one sample analyzer is indirectly electrically connected to the main control device via an intermediate data management device for managing sample data of the sample detection system.
14. The sample detection system of claim 13, wherein each of the sample analyzers is electrically connected to the main control device so that the main control device obtains operational status parameters and fault information for each of the sample analyzers.
15. The sample detection system of claim 14, wherein the main control device comprises: a second display, wherein,
The second display is used for respectively displaying the operation state parameters and fault information of each sample analyzer in different display areas,
and/or the number of the groups of groups,
the second display is used for displaying the fault information of each sample analyzer respectively in different colors.
16. The sample detection system of claim 1, wherein the at least one sample analyzer is coupled to the corresponding feed mechanism by a communication link.
17. The sample detection system of claim 13, wherein the master control device is coupled to the at least one sample analyzer and the transmission control device is coupled to the master control device via a communication link.
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