CN112345781A - Sample detection system - Google Patents

Sample detection system Download PDF

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Publication number
CN112345781A
CN112345781A CN201910731070.7A CN201910731070A CN112345781A CN 112345781 A CN112345781 A CN 112345781A CN 201910731070 A CN201910731070 A CN 201910731070A CN 112345781 A CN112345781 A CN 112345781A
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Prior art keywords
sample
analyzer
feeding mechanism
fault
sample analyzer
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Granted
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CN201910731070.7A
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Chinese (zh)
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CN112345781B (en
Inventor
张军伟
郁琦
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1081Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins

Abstract

The present application relates to a sample detection system comprising: at least two sample analyzers and a transport apparatus, wherein the transport apparatus comprises: the conveying mechanism comprises at least two feeding mechanisms and a plurality of sections of conveying mechanisms, wherein the conveying mechanisms are sequentially connected, and a conveying channel is formed between the conveying mechanisms; at least two feeding mechanisms are arranged at intervals along the conveying direction of the conveying channel, and each feeding mechanism is provided with a detection channel; each sample analyzer corresponds to one feeding mechanism; at least one sample analyzer is electrically connected with the corresponding feeding mechanism to acquire and display fault information of the corresponding feeding mechanism. Because sample analysis appearance and feed mechanism usually adjacent setting, the distance is nearer, so when feed mechanism trouble, operating personnel can see trouble information nearby on sample analysis appearance for trouble information's discovery is more timely, quick.

Description

Sample detection system
Technical Field
The present application relates to the field of medical diagnostic equipment, and more particularly, to a sample detection system.
Background
CRP (C-reactive protein) is an acute phase reaction protein, is normally present in a small amount in human body fluid, is increased to different degrees in infectious diseases, and has important clinical application value. Particularly, with the rapid development of the point-of-care rapid detection technology in recent years, the application of CRP in clinical infectious diseases is more extensive, and the CRP is the focus of clinical research again.
The blood routine is one of three routine examinations, and is also one of the commonly used auxiliary examination means for doctors to diagnose the disease condition; doctors can assist in judging the physical condition by observing the number change and the morphological distribution of blood cells. The CRP has high correlation with the conventional blood detection result, and the CRP is often used for identifying bacterial infection and viral infection by doctors in combination with the conventional blood detection method due to the characteristics of simple operation, high detection speed, small amount of required samples and the like.
Among the current assembly line joint detection system, many sample analysis appearance are linked together through the track, in order to realize integrated control, every sample analysis appearance all is connected with total control equipment through solitary communication line, the track includes the multistage, every section track all sets up a track controller alone, the track controller also inserts also through communication line and always controls in the equipment, total control equipment generally all is the PC, existing data processing function, also there is the data display function.
In field application, an operator needs to operate on a PC and watch the difference between the state of the sample analyzer and a display interface in real time, but a plurality of sample analyzers are connected with the same PC, so that the distance between some sample analyzers and the PC is relatively long, and especially when some sample analyzers are debugged for faults, the operator can move between the PC and the sample analyzers for many times, which is very inconvenient.
Disclosure of Invention
To solve the above technical problem or at least partially solve the above technical problem, the present application provides a sample detection system.
A sample detection system, comprising: at least two sample analyzers and a transport apparatus, wherein the transport apparatus comprises: the conveying device comprises at least two feeding mechanisms and a plurality of sections of conveying mechanisms, wherein the conveying mechanisms are sequentially connected, and a conveying channel for transferring a sample rack with a sample container is formed between the conveying mechanisms; at least two feeding mechanisms are arranged at intervals along the conveying direction of the conveying channel, and each feeding mechanism is provided with a detection channel;
each sample analyzer corresponds to one feeding mechanism, and the detection area of each sample analyzer corresponds to the detection channel of the corresponding feeding mechanism;
at least one sample analyzer is electrically connected with the corresponding feeding mechanism to acquire and display fault information of the corresponding feeding mechanism.
Optionally, each sample analyzer is electrically connected with the corresponding feeding mechanism to acquire and display fault information of the corresponding feeding mechanism.
Optionally, the at least one sample analyzer comprises a CRP analyzer for detecting C-reactive protein.
Optionally, each sample analyzer corresponds to at least one of the transport mechanisms;
the at least one sample analyzer is electrically connected with the corresponding transmission mechanism to acquire and display fault information of the transmission mechanism corresponding to the at least one sample analyzer.
Optionally, the at least one sample analyzer is electrically connected with a controller of the corresponding feeding mechanism and electrically connected with an electrical component of the corresponding feeding mechanism through the controller, the controller being configured to acquire an operating parameter of the electrical component;
the controller is further configured to determine fault information from the operating parameters and send the fault information to the at least one sample analyzer; or the controller sends the operation parameters to the at least one sample analyzer, and the at least one sample analyzer determines the fault information of the corresponding feeding mechanism according to the operation parameters.
Optionally, the at least one sample analyzer is in direct electrical connection with the electrical components of the corresponding feed mechanism; the at least one sample analyzer receives operating parameters of electrical components connected thereto and determines fault information of a corresponding feed mechanism according to the operating parameters.
Optionally, the at least one sample analyzer further comprises: a first operation device for receiving a failure removal operation corresponding to the failure information;
the at least one sample analyzer is further configured to generate and send a fault-handling signal corresponding to the fault-elimination operation to the corresponding feed mechanism and/or transport mechanism.
Optionally, the transmission device further includes: a second operating device;
the second operation equipment is electrically connected with the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and is used for receiving the fault elimination operation, generating a fault processing signal corresponding to the fault elimination operation and sending the fault processing signal to the connected feeding mechanism and/or transmission mechanism.
Optionally, the transmission device further includes: a local prompter;
the local prompter is electrically connected with the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and is used for receiving fault information sent by the at least one sample analyzer and/or the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and prompting locally.
Optionally, the feeding mechanism corresponding to the at least one sample analyzer and/or the transport mechanism corresponding to the at least one sample analyzer are initialized after receiving the fault handling signal.
Optionally, the transmission device further includes: a sample holder detector;
and the sample rack detector detects whether a sample rack exists on the initialized feeding mechanism and/or the initialized transmission mechanism, and when the sample rack detector does not detect the sample rack, the fault corresponding to the fault processing signal is determined to be eliminated.
Optionally, the sample detection system further comprises: a transmission control device;
the transmission control device is electrically connected with the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and acquires fault information of the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer, and when the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer is in fault, the dispatching of the sample rack to the at least one sample analyzer is stopped.
Optionally, the at least one sample analyzer further comprises a first display for displaying the fault information.
Optionally, the sample detection system further comprises: a main control device, wherein,
the at least one sample analyzer is in direct electrical connection with the main control device; the main control equipment is used for acquiring the running state parameters and the fault information of the at least one sample analyzer;
or, the at least one sample analyzer is indirectly electrically connected with the main control device through an intermediate data management device, and the intermediate data management device is used for managing sample data of the sample detection system.
Optionally, each sample analyzer is electrically connected to the main control device, so that the main control device can obtain the operation state parameters and the fault information of each sample analyzer.
Optionally, the main control device includes: a second display, wherein, when the first display is in the first display,
the second display is used for respectively displaying the operation state parameters and the fault information of each sample analyzer in different display areas,
and/or the presence of a gas in the gas,
the second display is used for displaying the fault information of each sample analyzer in different colors.
Optionally, the at least one sample analyzer is connected to the corresponding feed mechanism via a communication link.
Optionally, the main control device and the at least one sample analyzer, and the main control device and the transmission control device are connected by a communication link.
Compared with the prior art, the technical scheme provided by the embodiment of the application has the following advantages:
according to the sample detection system provided by the embodiment of the application, at least one sample analyzer can be electrically connected with the corresponding feeding mechanism, so that the sample analyzer can acquire and display the fault information of the corresponding feeding mechanism. Because sample analysis appearance and feed mechanism usually adjacent setting, the distance is nearer, so when feed mechanism trouble, operating personnel can see trouble information nearby on sample analysis appearance for trouble information's discovery is more timely, quick.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the invention and together with the description, serve to explain the principles of the invention.
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without inventive exercise.
Fig. 1 is a schematic structural diagram of a sample detection system according to an embodiment of the present disclosure;
FIG. 2 is a schematic structural diagram of another sample detection system provided in an embodiment of the present application;
FIG. 3a is a schematic structural diagram of another sample detection system provided in an embodiment of the present application;
FIG. 3b is a schematic structural diagram of another sample detection system provided in the embodiments of the present application;
fig. 4 is a schematic diagram of a display interface provided in an embodiment of the present application;
FIG. 5 is a schematic structural diagram of another sample detection system provided in an embodiment of the present application;
FIG. 6 is a schematic structural diagram of another sample detection system provided in an embodiment of the present application;
FIG. 7 is a schematic structural diagram of another sample detection system provided in an embodiment of the present application;
FIG. 8 is a schematic structural diagram of another sample detection system provided in an embodiment of the present application;
fig. 9 is a schematic structural diagram of a feeding mechanism of a sample analyzer according to an embodiment of the present disclosure;
FIG. 10 is a schematic diagram of a loading mechanism provided with the sample testing system of the present application;
FIG. 11 is a schematic diagram of a loading buffer provided in the sample testing system of the present application;
FIG. 12 is a schematic diagram of a sample rack provided in the sample testing system of the present application;
fig. 13 is a schematic structural diagram of a data processing apparatus according to an embodiment of the present application;
fig. 14 is a schematic structural diagram of another sample detection system according to an embodiment of the present disclosure.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are some embodiments of the present application, but not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
Example 1
Fig. 1 is a schematic structural diagram of a sample detection system according to an embodiment of the present disclosure. As shown in fig. 1, the sample detection system includes: at least two sample analyzers and a transport device.
Here, at least two sample analyzers may each have an internal controller themselves.
In fig. 1, at least two sample analyzers are illustrated by way of example as a hematology analyzer 10 and a CRP analyzer 20. Of course, in embodiments of the present application, the at least two sample analyzers may include a combination of at least two or more of a hemocytometer, a CRP analyzer, a slide stainer, and a saccharifier.
The transport device is used for transporting the sample rack of the sample container loaded with blood, and the sample container can be transported to any sample analyzer for detection through the transportation of the transport device.
Referring to fig. 1, the conveying apparatus includes a plurality of sections of conveying mechanisms (as shown in fig. 1, there are four conveying mechanisms, 51, 52, 53, 54 in the figure) connected with each other, and at least two feeding mechanisms (41, 42), wherein the plurality of sections of conveying mechanisms (51, 52, 53, 54) are connected end to end in sequence, and adjacent conveying mechanisms are connected with each other, or a gap which does not affect the conveying of the sample rack is arranged between adjacent conveying mechanisms. A transmission channel for transferring a sample rack with a sample container can be formed between the multiple sections of transmission mechanisms, and when the sample in the sample container is detected, the sample container can be driven by the transmission mechanism to move in the transmission channel.
At least two feeding mechanisms are arranged at intervals along the conveying direction of the conveying channel, in the embodiment of the application, as shown in fig. 1, the conveying direction is X, two feeding mechanisms (41, 42, wherein the whole of the dashed line frame shown by 42 is the feeding mechanism) are arranged in sequence, a space is arranged between any two feeding mechanisms, the size of the space can be freely set according to the field, each feeding mechanism (41, 42) is provided with a detection channel, so that the sample rack sent from the conveying channel can be transferred to the detection channel of the feeding mechanism, and the sample rack detected in the detection channel can be transferred to the conveying channel.
In a specific application, the conveying mechanisms (51, 52, 53, 54) can adopt any one or a combination of a chain type mechanism, a crawler type mechanism, a belt type mechanism, a roller type mechanism and a track type mechanism, and generally the same type of mechanism is adopted for the multi-stage conveying mechanism for maintenance and maintenance.
In the embodiment of the present application, the transport mechanism (51, 52, 53, 54) is not limited as long as it can transport the sample rack, and the shape of the transport path is, for example: the transmission channel can be a linear type, a broken line with a certain angle or an arc line with a certain radian, and even an irregular shape.
In the embodiment of the present application, the transmission channel may be a planar channel, for example: the upper surface of a belt of the belt type mechanism is directly used as a transmission channel; in addition, considering that the sample rack may fall or twist in position when being transferred, the transmission channel may be a semi-enclosed channel, such as: the baffle plates are arranged on two sides of the belt type mechanism, and the top of each baffle plate is not sealed, so that a semi-enclosed type transmission channel is formed in an area enclosed by the baffle plates, and the sample rack is restrained by the baffle plates and cannot fall off or be twisted in position. In addition, considering that the sample rack may be placed in a mess after being manually taken when being transferred, the transmission channel may also be a totally enclosed channel, for example: the baffle plates are arranged on the two sides and the top of the belt type mechanism, so that the problem of manual intervention can be avoided when the sample rack is transferred in the transmission channel.
In the embodiment of the application, the transmission channel is used as a main channel, each detection channel is used as a sub-channel, and the transmission channel is basically parallel to the detection channels. When the sample rack detection device works, the conveying mechanism can transfer the sample rack to the position of each feeding mechanism (41, 42) on the conveying channel, then the feeding mechanisms (41, 42) transfer the sample rack from the conveying channel to the corresponding detection channel, the feeding mechanisms (41, 42) drive the sample rack to move in the detection channel, and after the detection of the sample rack is completed, the feeding mechanisms (41, 42) can also transfer the sample rack from the detection channel back to the conveying channel.
One feeding mechanism may be provided for each sample analyzer, and the detection zone of each sample analyzer corresponds to the detection channel of its corresponding feeding mechanism, for example, in fig. 1, the detection zone of the blood analyzer 10 corresponds to the detection channel of the feeding mechanism 42, and the detection zone of the CRP analyzer 20 corresponds to the detection channel of the feeding mechanism 41. In the embodiment of the present application, the correspondence between the detection area and the detection channel means: the detection channel coincides with the detection area, or the detection area is located in the detection channel. This ensures that the sample rack can be collected by the CRP analyzer 20 or the blood cell analyzer 10 from the sample container on the sample rack when the sample rack moves along the detection path, and the collected sample can be used for detection and analysis.
In the embodiment of the present application, the feeding mechanisms (41, 42) may also adopt any one or more combinations of a chain type mechanism, a crawler type mechanism, a belt type mechanism, a roller type mechanism and a rail type mechanism, and if a plurality of combinations are adopted, the feeding mechanisms (41, 42) may be provided with a plurality of sections of mechanisms with different styles. For a detailed description of the feeding mechanism, reference is made to the preceding description of the transport mechanism. And will not be described in detail herein.
In the present embodiment, each sample analyzer corresponds to a corresponding feed mechanism. In one embodiment, each sample analyzer corresponds to one feeding mechanism, i.e., the sample analyzers correspond to one feeding mechanism, and as shown in fig. 1, the CRP analyzer 20 corresponds to the feeding mechanism 41, and the blood cell analyzer 10 corresponds to the feeding mechanism 42. This allows the sample in the sample container on the sample rack to be subjected to CRP analysis in the CRP analyzer 20 or to corresponding hemacytometer analysis in the hemacytometer 10 during testing. In another embodiment, there may also be a plurality of sample analyzers associated with the same feed mechanism, for example, CRP analyzer 20 is associated with feed mechanism 41, and blood cell sample analyzer 10 and another blood cell analyzer (not shown) are associated with feed mechanism 42.
The CRP analyzer 20 is used to detect C-reactive protein in samples transferred from the transport mechanism to sample containers on sample racks in the corresponding detection lanes. The other sample analyzers are used for detecting other blood components except the C-reactive protein of the sample in the sample container on the sample rack in the corresponding detection channel transferred by the transmission mechanism, such as: hemoglobin, WBC (white blood cells), NEUT (neutral cells), LYMPH (lymphocytes), EO (eosinophils), BASO (basophils), and MONO (monocytes), and the like.
All sample analyzers can be arranged in any order in the direction of the transport path, as shown in fig. 1, with the hematology analyzer 10 in front of the CRP analyzer 20 in the transport direction X along the transport path.
In the present embodiment, "front" and "rear" are both relative concepts, where "front" refers to a position that passes first along the transport direction X, and "rear" refers to a position that passes later along the transport direction X, and the blood cell analyzer 10 is located in front of the CRP analyzer 20, that is, the sample rack on the transport path passes through the blood cell analyzer 10 first, and then passes through the CRP analyzer 20. Taking the direction shown in fig. 1 as an example, if the transport direction X is from right to left, then "front" refers to a position relatively to the right in the figure, and "rear" refers to a position relatively to the left in the figure, and therefore "front" and "rear" in the present application describe the relative positional relationship between the blood cell analyzer 10 and the CRP analyzer 20, and should not be understood in a literal sense, and thus the present application is limited thereto.
In the embodiment of the application, at least one sample analyzer is electrically connected with the corresponding feeding mechanism to acquire and display the fault information of the corresponding feeding mechanism, so that the sample analyzer electrically connected with the feeding mechanism has a fault display function, and can be referred to as a sample analyzer with the fault display function in the following.
As shown in fig. 1, in the solution shown in fig. 1, the CRP analyzer 20, for example an internal controller of the CRP analyzer 20, is electrically connected to the corresponding feed mechanism 41, where the purpose of the electrical connection is that the CRP analyzer 20 can communicate with the feed mechanism 41, so the electrical connection can be an electrical connection, communicating with electrical signals; the electrical connection may also be a conventional communication connection, and the control instructions may be used to communicate, and in any case, the CRP analyzer 20 may be caused to acquire the fault information of the corresponding feed mechanism 41 by the electrical connection and then to display the fault information on the CRP analyzer 20.
In the embodiment of the present application, the sample analyzer with the failure display function may include: a first display. A failure information is displayed in the first display.
The first display may be a touch screen, LED display screen, or other screen on which a picture may be displayed.
When the fault information is displayed, the fault information can be displayed in a fixed fault display area in the first display, and the fault information can also be displayed in a pop-up window mode.
According to the sample detection system provided by the embodiment of the application, at least one sample analyzer can be electrically connected with the corresponding feeding mechanism, so that the sample analyzer can acquire and display the fault information of the corresponding feeding mechanism. Because sample analysis appearance and feed mechanism usually adjacent setting, the distance is nearer, so when feed mechanism trouble, operating personnel can see trouble information nearby on sample analysis appearance for trouble information's discovery is more timely, quick.
Example 2
In an embodiment of the present application, each sample analyzer in the detection system may be electrically connected to the corresponding feeding mechanism, so that each sample analyzer may obtain and display the failure information of the corresponding feeding mechanism.
As shown in fig. 2, in addition to the CRP analyzer 20 being electrically connected to the feeding mechanism 41, the hematology analyzer 10 may also be electrically connected to the feeding mechanism 42, so that the CRP analyzer 20 can display failure information corresponding to the feeding mechanism 41 and the hematology analyzer 10 can display failure information corresponding to the feeding mechanism 42.
Furthermore, in the embodiment of the present application, the sample analyzer is electrically connected to the corresponding feeding mechanism, and the sample analyzer can also control the movement of the corresponding feeding mechanism, for example: as in fig. 1, the CRP analyzer 20 may control the corresponding feed mechanism 41 to transfer the sample rack on the transport lane to the corresponding detection lane, to move the sample rack in the detection lane, and to transfer the sample rack from the detection lane to the transport lane. Alternatively, after the hematology analyzer 10 is electrically connected to the feeding mechanism 42, the hematology analyzer 10 may control the feeding mechanism 42 to move the sample rack on the transport channel to the corresponding detection channel, move the sample rack in the detection channel, and move the sample rack from the detection channel to the transport channel.
In the sample testing system provided in the embodiment of the present application, the CRP analyzer 20 is electrically connected to its corresponding feeding mechanism 41, so that the CRP analyzer 20 can independently control the corresponding feeding mechanism 41 to operate. Thus, the CRP analyzer 20 can be used as a relatively independent unit to independently control the detection process of the sample rack from the transmission channel to the detection channel, and no external equipment is needed to participate in control, in the assembly line joint detection system, if CRP analysis items need to be added, the CRP analyzer 20 and the corresponding feeding mechanism 41 are directly added to the transmission channel, a control flow and equipment for the feeding mechanism 41 do not need to be added, only the transmission mechanism in the transmission channel needs to be maintained, and for the transmission mechanism, one more sample analyzer needs to be added, and only the scheduling program on the transmission mechanism needs to be adjusted.
Therefore, the sample detection system is simple in control function when the production line is controlled, the layout cost is low, and particularly, when the sample detection system is used for detecting CRP projects according to needs, only the control flow of a transmission channel of the production line needs to be adjusted, the original production line does not need to be modified in a complex mode, so that the CRP projects can be expanded on the production line quickly, and the system is convenient and simple.
Example 3
The sample analyzer with the fault display function can be connected with a corresponding feeding mechanism, and can be realized in various ways in specific implementation.
In one embodiment of the present application, each feeding mechanism has an electrical component, in particular an electrical actuator, and the electrical actuator may include: driving motor, relay, solenoid valve, drive actuating cylinder, drive guide rail etc. electric executive component can be controlled and move, and then drive the sample frame and remove. At least one sample analyzer is electrically connected directly to the corresponding electrical component of the feed mechanism; the at least one sample analyzer receives operating parameters of electrical components connected thereto and determines fault information of a corresponding feed mechanism according to the operating parameters.
This is to be taken into account that, since the feed movements of the feed mechanism are each driven by internal electrical components, in particular electrical actuators, in one embodiment of the application, as shown in fig. 1, the CRP analyzer 20 can be connected directly electrically to electrical components, in particular electrical actuators, in the feed mechanism 41. On the one hand, the electrical actuator in the feed mechanism 41 may send the operating parameters to the CRP analyzer 20 to cause the sample analyzer to determine fault information in the feed mechanism 41 based on the operating parameters, and on the other hand, the CRP analyzer may also control the movement of the electrical actuator by sending electrical signals to the electrical actuator to drive the movement of the feed mechanism 41.
In another embodiment of the present application, at least one sample analyzer is electrically connected to a controller of a corresponding feed mechanism and electrically connected to electrical components of the corresponding feed mechanism through the controller, wherein the controller is configured to acquire operating parameters associated with the electrical components; the controller is further configured to determine fault information from the operating parameters and send the fault information to the at least one sample analyzer; or the controller sends the operation parameters to the at least one sample analyzer, and the at least one sample analyzer determines the fault information of the corresponding feeding mechanism according to the operation parameters.
As shown in fig. 3a, in order to realize centralized and normative control of the feeding mechanism 41, a controller 61 may be further provided in the feeding mechanism 41, and the controller 61 may be electrically connected not only to the electric actuator but also to the CRP analyzer 20 through a communication link (including a wired communication link and a wireless communication link). In the embodiment of the present application, the communication link may be an RS232 link, so that, on one hand, the controller 61 may collect the operation parameters of the electrical execution component and forward the operation parameters to the CRP analyzer 20, so that the CRP analyzer 20 determines the fault information of the feeding mechanism 41 according to the operation parameters; alternatively, the CRP analyzer 20 can send control signals directly to the controller 61, with the controller 61 controlling the movement of the internal electrical actuators of the feed mechanism. In specific implementation, the controller 61 may be implemented by an electronic device with arithmetic capability, such as a single chip or a programmable logic controller.
In other embodiments of the present application, the control of the feed mechanism 41 may also be integrated within the CRP analyzer 20, for example into an internal control of the CRP analyzer 20, or the control of the feed mechanism 41 may be a separate control provided in the feed mechanism.
Example 4
Referring to the description of the embodiment shown in fig. 1, each of the sample analyzers corresponds to at least one of the transport mechanisms, such as: the CRP analyzer 20 corresponds to the transport mechanism 52 and the blood cell analyzer 10 corresponds to the transport mechanism 53.
In the embodiment of the application, the sample analyzer for displaying the fault information is further electrically connected with the corresponding transmission mechanism to acquire and display the fault information of the transmission mechanism corresponding to the at least one sample analyzer.
For example: the CRP analyzer 20 is also electrically connected to the transport mechanism 52, as described above with respect to the sample analyzer electrically connected to the feed mechanism, and in one embodiment of the application, the sample analyzer with fault indication can be electrically connected directly to the electrical actuator of the transport mechanism. In another embodiment of the present application, the sample analyzer with failure display function may be electrically connected to both the corresponding feeding mechanism and the corresponding electric actuator in the transport mechanism at the same time through the controller, and as shown in fig. 3b, the CRP analyzer 20 may be electrically connected to both the electric actuator in the feeding mechanism 41 and the electric actuator in the transport mechanism 52 at the same time through the controller 61.
In other embodiments, the controller 61 may be shared with other mechanisms besides the feeding mechanism 41 and the transport mechanism 52, such as: the feeding mechanism 42 and the transfer mechanism 53 are shared, and the like. In any case, the present application protects that the CRP analyzer can obtain the fault information of the feeding mechanism and/or the transport mechanism belonging thereto, so the present application does not limit the specific connection relationship and the control relationship between the CRP analyzer and the corresponding feeding mechanism and/or transport mechanism.
Example 5
The sample detection system provided by the foregoing may enable the sample analyzer to obtain and display the fault information of the corresponding feeding mechanism, but in practical application of the sample analyzer, when a fault occurs, the fault needs to be handled.
For this reason, in the embodiment of the present application, under one scenario: and the sample analyzer with the fault display function is also used for generating a fault processing signal corresponding to the fault elimination operation and sending the fault processing signal to any one or two of the corresponding feeding mechanism and the corresponding transmission mechanism so as to carry out fault processing on the feeding mechanism or the transmission mechanism with the fault.
In the above scenario, the sample analyzer may set fault handling policy information, and once the fault information is determined, the corresponding fault handling policy may be searched, and a fault handling signal may be generated, so that fault handling may be performed automatically. The fault handling policy information may be a database or a fault handling table.
In another scenario, the sample analyzer with fault display function further includes: a first operation device for receiving a failure removal operation corresponding to the failure information; and the sample analyzer with the fault display function is also used for generating a fault processing signal corresponding to the fault elimination operation and sending the fault processing signal to the corresponding feeding mechanism.
The first operating device may be a common input device, such as: the touch screen, the keyboard, the mouse, the rocker or the electric control button, and the like, when the first operating device adopts the touch screen, the first operating device is a virtual key on the touch screen. The troubleshooting operation may be a virtual key operation, such as: the virtual buttons displayed on the touch screen or the display screen are controlled by clicking the virtual buttons on the touch screen, or by clicking the virtual buttons on the display screen with a keyboard or a mouse, or may be physical keys, for example: the rocker or the electric control button is operated to directly generate a control electric signal.
In specific application, an operator can directly input a fault elimination operation by using the first operation device according to the actual fault information. In addition, in other embodiments of the present application, when displaying the fault information, the fault handling policy corresponding to the fault information may also be displayed at the same time, so that an operator may input the fault removing operation according to the fault handling policy.
When the fault information is displayed in the fault display area, if the fault information area is clicked, a popup window corresponding to the fault information may also be displayed in a popup window form, as shown in fig. 4, which is illustrated by taking a touch screen as an example in fig. 4, where fig. 4 includes: a first display 201, a pop-up window 202, a failure display area 203, a help display area 204, and operation buttons 205. In the failure display area, 3 failure names corresponding to the failure information are displayed, and when the 1 st failure name is clicked, the failure handling policy corresponding to the 1 st failure name is displayed in the help display area 204.
The operation button 205 is used to facilitate the operation of the operator according to the name of the fault, and the operator in fig. 4 clicks the "remove fault" button displayed on the touch screen, and the sample analyzer will automatically remove the currently removable fault. And for the faults which cannot be automatically eliminated, the operator can carry out corresponding fault treatment according to the fault help information. The operator clicks the "cancel alarm sound" button to cancel the alarm sound of the host. The operator clicks the "close" button to close the fault dialog, but the fault information area on the interface will display the corresponding fault information. If the trouble information area is clicked again, the trouble dialog may be opened again.
In other embodiments of the present application, the fault handling strategy can also be seen in table 1 below.
TABLE 1
Figure BDA0002160605190000151
Example 6
In the foregoing embodiment 5, the first operation device is disposed on the sample analyzer with the failure display function, so that an operator can operate the sample analyzer conveniently, in this embodiment, the transmission device may further include: a second operating device.
The second operating device may be provided on the transport mechanism as well as on the feed mechanism.
And the second operating equipment is electrically connected with any one or two of the feeding mechanism and the transmission mechanism corresponding to the sample analyzer with the fault display function, and is used for receiving the fault elimination operation, generating a fault processing signal corresponding to the fault elimination operation and sending the fault processing signal to any one or two of the feeding mechanism and the transmission mechanism which are connected.
The second operating device may be a common input device, such as: touch screen, keyboard, mouse, joystick or electrical control button, etc. The troubleshooting operation may be a virtual key operation, such as: the virtual buttons displayed on the touch screen or the display screen are controlled by clicking the virtual buttons on the touch screen, or by clicking the virtual buttons on the display screen with a keyboard or a mouse, or may be physical keys, for example: the rocker or the electric control button is operated to directly generate a control electric signal.
Example 7
For all the foregoing embodiments, the failure display of the feeding mechanism is implemented in the sample analyzer with failure display function, in practical application, in order to facilitate the operator to more intuitively know the location of the failure, in the embodiment of the present application, the transmission device may further include: a local prompter.
The local prompter is electrically connected with any one or two of the feeding mechanism and/or the transmission mechanism corresponding to the sample analyzer with the fault display function, and is used for receiving fault information sent by the sample analyzer with the fault display function or fault information sent by any one or two of the feeding mechanism and the transmission mechanism corresponding to the sample analyzer with the display function and locally prompting.
The local alarm is usually arranged on the feed mechanism or transport mechanism of the transport device, or else can be arranged next to the feed mechanism or transport mechanism. Therefore, when the local prompter prompts, the position of the fault can be indicated.
In the embodiment of the present application, the local prompter may be a common alarm of sound, light, electricity, etc., such as: LED pilot lamp, loudspeaker, display screen etc. still can be for other mechanical motion equipment that receive electric signal control, indicate through the motion of mechanical motion equipment.
Example 8
In all the embodiments described above, the acquisition and display of the fault are described, and in the embodiment of the present application, when the feeding mechanism or the conveying mechanism is faulty, the system can also handle the fault.
For this reason, in the embodiment of the present application, the sample analyzer with a failure processing function is initialized after receiving a failure processing signal from either one or both of the feeding mechanism and the transport mechanism.
Initialization is one of the most common operations of fault handling, and in other embodiments of the present application, after the feeding mechanism or the transmission mechanism receives the fault handling signal, the operation corresponding to the fault handling signal may be further performed, for example: reset, etc.
In practical application, after initialization, whether the feeding mechanism or the conveying mechanism has residual sample racks needs to be judged, and if the residual sample racks exist, the residual sample racks cannot be scheduled, so that the initial fault is determined to be still not eliminated. The failure is only determined if there are no remaining sample racks on the feed mechanism or transport mechanism after initialization.
To this end, in an embodiment of the present application, the transmission device further includes: a sample holder detector; and the sample rack detector detects whether a sample rack exists on the initialized feeding mechanism and/or the initialized transmission mechanism, and when the sample rack detector does not detect the sample rack, the fault corresponding to the fault processing signal is determined to be eliminated.
The sample rack detector may be a camera, a sensor having a shielding detection function such as a photoelectric gate, or a pressure sensor, and the sample rack detector may monitor whether a sample rack is present in a specific area (an area corresponding to the distribution mechanism of the transport mechanism).
Example 9
FIG. 5 is a schematic view of another embodiment of the sample detection system of the present application.
As shown in fig. 5, the difference from the previous embodiment is: the sample detection system further comprises: a main control device 30.
In the exemplary embodiment of the present application, at least one sample analyzer (here, CRP analyzer 20 and hematology analyzer 10), in particular all sample analyzers, is electrically connected to main control device 30, and main control device 30 is added to collect measurement result data and instrument status data of the sample analyzers, including fault information, and to perform centralized management and display.
In a specific application, for the CRP analyzer and all sample analyzers jointly tested in the production line, the testing results need to be collected together, so that the testing personnel can quickly know the fault information and/or the testing results of all the analyzers.
In this embodiment, the main control device 30 may also be directly electrically connected to the at least one sample analyzer, such as the CRP analyzer 20, for example, an internal controller thereof, and in one scenario, the main control device 30 may be connected to the at least one sample analyzer, such as the CRP analyzer 20, through a communication network (for example, an ethernet network), so as to facilitate the at least one sample analyzer, such as the CRP analyzer 20, to report the detection result and the instrument state data.
For the pipeline detection system, an intermediate data management device for data management and interaction may also be provided, and in another embodiment of the present application, as shown in fig. 6, the diagram includes: the router 31 and the intermediate data management device 32, the CRP analyzer 20 is connected to the intermediate data management device 32 through the network, the intermediate data management device 32 is connected to the router 31 through the network, the main control device 30 can also be connected to the intermediate data management device 32 through the router 31, and thus the CRP analyzer 20 can transmit data to the main control device 30 through the intermediate data management device 32.
In the embodiment of the present application, the intermediate data management device 32 is used for managing data of the sample detection system, including detection data of the sample analyzer, status data of the sample transport device, sample data, and the like. The intermediate data management device 32 may have functions of information inquiry, data presentation, result audit, result transmission, report printing, and the like. The information query may ask a Laboratory Information System (LIS) for patient-related information. And result auditing can be performed manually or automatically, and measurement modes can be increased or decreased according to rules, so that the result auditing method acts on the sample analyzer.
In the embodiment of the present application, the intermediate data management device 32 may be in the form of software, or a hardware integrated chip, etc. The intermediate data management apparatus 32 may be located on an instrument in the sample detection system (e.g., the hematology analyzer 10 or the main control device 30), or may be located on another terminal device. In this exemplary embodiment, the sample analyzer, for example the blood cell analyzer 10 or the CRP analyzer 20, can transmit its operating state parameters and/or fault information and/or test data to the intermediate data management device 32 and display them on the device in which the intermediate data management device 32 is installed.
In another embodiment of the present application, a main control apparatus includes: and the second display is used for respectively displaying the operation state parameters and the fault information of each sample analyzer in different display areas in one scene. The display areas of the data of different sample analyzers on the second display are different, so that an operator can quickly and conveniently know the running state parameters and the fault information of each sample analyzer through the second display,
in another scenario, the second display is configured to display the failure information of each of the sample analyzers in different colors, respectively.
The fault information is displayed through different colors, after an operator skillfully grasps the corresponding relation between the colors and the fault information, the current fault information can be quickly and intuitively known through the colors, and the details of the fault information displayed in the second display can be further watched in detail.
In specific application, the fault information is uniformly displayed in the fault display area, and then different colors can be used for representing different fault information in the fault display area, or different colors can be used for representing the fault information of different sample analyzers.
In one embodiment of the present application, the background colors used in the fault information area may be red, orange, blue and green in sequence according to the fault level from high to low.
Red: indicating a fatal level of failure. Upon such a failure, the current action should be terminated immediately and any action on it should be prohibited.
Orange color: indicating a malfunction of the disable stage. Upon such a failure, the current action should be terminated immediately.
Blue color: the indication is a fault at the limit level. After such a failure, the current operation may still continue to be performed, but other operations associated with such a failure are restricted.
Green: the indication is a fault at the cue level. After such a failure, the current operation can be continued without restricting any other operation.
Example 10
As shown in fig. 7, for another embodiment provided in the present application, the sample detection system provided in this embodiment may further include: the transmission control device 90.
The transmission control device is electrically connected with the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and acquires fault information of the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer, and when the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer is in fault, the dispatching of the sample rack to the at least one sample analyzer is stopped.
The transport control device 90 is used for scheduling the sample rack to be moved in the transport path and the detection path, and can be moved to a position corresponding to any one of the feeding mechanisms in the transport path, so as to feed the sample rack into the CRP analyzer or other sample analyzers for detection. In the embodiment of the present application, the transmission control device 90 may employ an electronic device having arithmetic capability, such as a single chip microcomputer or a programmable logic controller. In addition, the transmission control device 90 and each transmission mechanism may be connected to each other through a CAN bus.
In a specific application, each transmission mechanism may be provided with a controller individually, or a plurality of transmission mechanisms may share one controller, for example, 62 in the diagram shown in fig. 7 is a controller, and 62 is shared by a plurality of transmission mechanisms, the controller 62 is connected to an electrical component in the transmission mechanism for controlling the movement of the transmission mechanism, and the controller 62 may be a single chip or a programmable logic controller.
The transmission control device 90 may also be electrically connected to the main control device 30 through a communication network, as shown in fig. 5, and the transmission control device 90 is connected to the main control device 30 through the router 31, so as to obtain the collected instrument state data of the sample analyzer from the main control device 30 for sample rack scheduling.
In the combined detection process of the production line, the sample rack flows among different sample analyzers, in order to better control the operation of the sample rack in a transmission channel and a detection channel and avoid the problem of channel blockage caused by long-time waiting, the current working state of the sample analyzer needs to be mastered, the scheduling of the sample rack can be reasonably arranged according to the current working state of the sample analyzer, such as fault information, under the most ideal condition, when the sample rack is scheduled to the detection channel corresponding to the CRP analyzer, the CRP analyzer is just in an idle state, the blood sample in the sample container on the sample rack can be directly detected, and when the CRP analyzer is in a fault state, the scheduling of the sample rack to the CRP analyzer can be stopped.
Since the scheduling requires not only the transmission mechanism but also the feeding mechanism to be used for cooperation, in the embodiment of the present application, the transmission control device 90 is also connected to the CRP analyzer 20, and as shown in fig. 7, the transmission control device 90 is indirectly connected to the CRP analyzer 20 through the controller 61 so that the transmission control device 90 can transmit the scheduling information to the CRP analyzer 20. For example, when a sample rack is scheduled to the position of the transport mechanism 52, the transport control device 90 needs to send an in-position message to the CRP analyzer 20 so that the CRP analyzer 20 can control the feed mechanism 41 to remove the sample rack from the transport lane of the transport mechanism 52 and transfer to the detection lane of the feed mechanism 41.
The system provided by the embodiment of the application can acquire the scheduling condition from the transmission control device 90 for the CRP analyzer 20, and when receiving the in-place message, the feeding mechanism 41 is controlled to remove the sample rack from the transmission channel, and for the feeding mechanism, the CRP analyzer can be completely independently controlled without the participation of an external device (such as a main control device).
Example 11
In the embodiment of the present application, the feeding mechanisms corresponding to the CRP analyzer 20 may be controlled by the CRP analyzer alone, and for the feeding mechanisms of the remaining sample analyzers, the sample analyzers may also be controlled individually, and the scheduling control logic adopted by the feeding mechanisms is as follows: the main control equipment sends the instrument state information to the transmission control equipment, the transmission control equipment carries out scheduling according to the instrument state information and detection required to be carried out, the transmission mechanism is directly controlled during scheduling, and the corresponding feeding mechanism is controlled through the CRP analyzer.
Also, in the embodiment of the present application, each of the sample analyzers is electrically connected to a corresponding feeding mechanism, and each of the sample analyzers is configured to control the corresponding feeding mechanism to move out a sample rack on the transport lane and to transfer the sample rack to a corresponding detection lane, to move the sample rack in the detection lane, and to transfer the sample rack from the detection lane to the transport lane. As shown in fig. 7, the hematology analyzer 10 is shown connected to a feed mechanism 42.
This requires that each sample analyzer accurately knows whether a sample rack is scheduled in place on the transport path, and for this reason, in one embodiment of the present application, the transport control device may be electrically connected to each sample analyzer, and configured to send a location message to a corresponding sample analyzer when the sample rack is moved to a corresponding position of any sample analyzer in the transport path, so that the sample analyzer controls a corresponding feeding mechanism to move the sample rack out of the transport path.
Example 12
The feeding mechanisms corresponding to the CRP analyzer or other sample analyzers are controlled by the same scheduling logic, but the existing sample analyzers may not have a feeding mechanism control design inside, such as hardware or software, for controlling the feeding mechanisms of the sample analyzers, for this purpose, in the embodiment of the present application, the main control device may be electrically connected to the feeding mechanism corresponding to each sample analyzer, and configured to control the corresponding feeding mechanism to move the corresponding sample rack to the corresponding detection channel, move the sample rack in the detection channel, and move the sample rack out of the detection channel. In a particular application, as shown in fig. 8, the transmission control device 90 may also be connected to the main control device 30 via the router 31, the main control device 30 being directly connected to the feeding mechanism 42.
Thus, when the transport control device schedules the transfer of the sample rack, if the sample rack in the transport channel is in place at the position of the sample rack in the feeding mechanism 42 corresponding to the blood cell analyzer 20 (i.e. the sample rack on the transport channel is transferred to the position of the feeding mechanism 42 of the blood cell analyzer 20), the transport control device 90 may send a place message to the main control device 30 through the communication line, and the main control device 30 further controls the feeding mechanism 42 to move.
In other embodiments, when the feeding mechanism 42 and the transmission mechanism 53 share a controller communicatively connected to the transmission control device 90, the transmission control device 90 may also directly send the in-place message to the controller, thereby controlling the feeding mechanism 42 to move.
Example 13
Referring to fig. 9, a detailed result diagram of the feeding mechanism provided in the embodiment of the present application is shown. The in-position of the sample rack transferred to the CRP analyzer 20 on the transport path is shown by the dashed line box in fig. 9.
As shown in fig. 9, the feeding mechanism 41 corresponding to the CRP analyzer in the figure may include: drive mechanism 421, load buffer 422 and loading mechanism 423, wherein:
the transmission mechanism 421 may be any one or a combination of a chain mechanism, a crawler mechanism, a belt mechanism, a roller mechanism, and a track mechanism, and if a plurality of combinations are adopted, the transmission mechanism 421 may be provided with a plurality of sections of mechanisms of different types. In the embodiment of the present application, the transmission 421 has a detection passage formed therein. And the position of the detection channel corresponds to the position of the detection area of the CRP analyzer 20 corresponding to the feeding mechanism, so that the detection of the sample container transferred in the detection channel can be smoothly completed.
As shown in fig. 9, the loading buffer 422 is located between the detection channel and the transmission channel, and the loading buffer 422 mainly considers that if the number of sample racks transferred to the analyzer by the transmission channel is large, and the sample analyzer needs to consume a certain time to complete each sample rack, and if all the sample racks on the transmission channel are transferred to the sample analyzer, normal analysis and detection will be affected, the loading buffer 422 is provided, so that the sample racks transferred on the transmission channel are firstly buffered in the region, and then the sample racks buffered in the region are sequentially transferred to the detection channel according to the detection speed of the analyzer.
As shown in fig. 9, the loading mechanism 423 is located below the loading buffer 422, and is configured to move the sample rack passing through the transport path to the loading buffer 422, and to move the sample rack loaded in the loading buffer 422 to the detection path. The loading mechanism 423 lifts the sample rack on the transport path out of the transport path when the sample rack is moved to the home position shown in the dashed line box in fig. 9.
In the embodiment of the present application, the loading mechanism has two functions, that is, unloading the sample rack from the transport lane and transferring the sample rack in the loading buffer to the detection lane, so that the transport control device needs to send the in-place message of the sample rack to the CRP analyzer, so that the CRP analyzer can control the loading mechanism to unload the sample rack from the transport lane.
In the present embodiment, as shown in fig. 12, the loading mechanism 423 may include: a holder 131, a pusher 132, and a pusher driving device 133, the holder 131 being disposed between the transport path and the detection path for supporting the loading mechanism 423; the push claw 132 is arranged on the bracket 131 and is used for driving the sample rack stored in the loading buffer area to slide towards the detection channel or the transmission channel, so that the sample rack is transmitted between the transmission channel and the detection channel; the pawl driving device 133 is disposed on the bracket 131 for driving the pawl 132 to perform the above-mentioned movement process.
In an alternative embodiment, as shown in fig. 11, in the sample testing system of the embodiment of the present application, the loading buffer 422 includes: the panel 141 is used for carrying the sample rack, and the panel 141 is provided with a long hole 142 extending from the transmission channel to the detection channel. The pawl driving device 133 includes: the device comprises a horizontal pushing assembly 1331, a pusher claw mounting seat 1332 and a lifting assembly 1333, wherein the horizontal pushing assembly 1331 is arranged on the bracket 131 and can horizontally move relative to the bracket 131; the pusher jaw mounting seat 1332 is linked with the horizontal pushing assembly 1331, and the horizontal pushing assembly 1331 drives the pusher jaw mounting seat 1332 to horizontally move between the detection channel and the transmission channel; the lifting assembly 1333 is disposed on the pusher mounting base 1332, the pusher 132 is disposed on the lifting assembly 1333, the lifting assembly 1333 drives the pusher 132 to ascend, so that the pusher 132 at least partially penetrates through the long hole 142 on the panel 141 and is matched with the bottom of the sample rack, and the horizontal pushing assembly 13231 can drive the pusher mounting base 1332 to move horizontally, so that the pusher 132 drives the sample rack to slide toward the detection channel or the transmission channel on the panel 141. Alternatively, in order to position the moving position of the pusher jaw 132, a position sensor 135 is respectively disposed at two ends of the bracket 131 near the detection channel and the transmission channel, and the position sensor 135 can cooperate with the pusher jaw mounting seat 1332 or the pusher jaw 132 to make the system controller obtain the moving position of the pusher jaw 132. Position sensor 135 is preferably an opto-coupler, and a light coupling piece is arranged on pusher dog mount 1332, and when pusher dog mount 1332 moves to a position close to a detection channel or a transmission channel, the light coupling piece and the opto-coupler act with each other to enable the opto-coupler to send out an induction signal, so that the position of pusher dog 132 can be judged by a system controller.
In an alternative embodiment of the present application, the horizontal pushing assembly 1331 may be a motor synchronous belt driving mechanism, and a motor is used to drive a synchronous belt to rotate, so as to drive the pushing claw mounting seat 1332 to perform a horizontal movement. Of course, the horizontal pushing assembly 1331 may also be a linear motor, and the primary of the linear motor drives the pusher jaw mounting 1332 to perform a horizontal linear motion. In order to ensure stable operation of the claw mounting 1332, a linear guide may be mounted on the bracket 131, and the claw mounting 1332 may be slidably mounted on the linear guide. The lifting assembly 1333 may be a lifting cylinder, the cylinder body of the lifting cylinder is fixed on the pusher dog mounting seat 1332, the pusher dog 132 is fixedly connected to the piston rod of the lifting cylinder, and the piston rod of the lifting cylinder is controlled to drive the pusher dog 132 to move up and down.
As shown in fig. 12, the bottom of the sample rack 15 is provided with bottom slots 151 at intervals, and when the pushing claws 132 extend upwards from the long holes 142 on the panel 141, the pushing claws can be inserted into the bottom slots 151 of the sample rack 15, so as to drive the sample rack 15 to move synchronously. As can be seen, the sample rack 15 is provided with a plurality of detection sites 152.
Before the sample rack 15 shown in fig. 12 enters the analyzer for sampling analysis, the analyzer needs to scan the barcode of the sample container on the sample rack 15 to obtain a sampling analysis task corresponding to the sample, so that a scanning hole 153 is formed in the sidewall of the sample rack 15 corresponding to each detection position, so that the scanner can scan the container identifier attached to the sample container.
In an alternative embodiment, as shown in fig. 9, the feeding mechanism further comprises: an unloading buffer area 424 and an unloading mechanism 425, wherein the unloading buffer area 424 is located between the detection channel and the transmission channel, and the unloading buffer area 424 and the loading buffer area 422 are arranged at intervals along the transmission direction of the detection channel, as shown in fig. 9, the loading buffer area 422 and the unloading buffer area 425 are respectively located at two ends of the detection channel; an unloading mechanism 425, located at the unloading buffer area, is used for transferring the sample rack passing through the detection channel to the unloading buffer area 424, and transferring the sample rack in the unloading buffer area 424 to the transmission channel.
In the embodiment of the present application, for a detailed structure of the unloading mechanism, reference may be made to the foregoing description of the loading mechanism, and details are not described herein.
Example 14
In other embodiments of the present application, the loading mechanism may also only be responsible for moving the sample rack loaded in the buffer to the detection channel, but not for removing the sample rack from the transport channel, and for this reason, in this embodiment of the present application, the transport mechanism may further include: at least one dispensing mechanism. The dispensing mechanism may be configured, for example, as a pusher for pushing the sample rack on the transport path onto the load buffer.
Each distribution mechanism corresponds to one feeding mechanism, particularly to a loading buffer area of the feeding mechanism, and the transmission control device is used for controlling the corresponding distribution mechanism to move out the sample rack on the transmission channel when the sample rack is transferred to a corresponding position of any sample analyzer in the transmission channel.
In this case, the transport mechanism may directly transfer the sample rack to the load buffer of any one of the feeding mechanisms at the time of scheduling without notification to the sample analyzer.
Accordingly, for the feeding mechanism, without the in-place message, the details of the schedule cannot be known, and for this reason, in the embodiment of the present application, the feeding mechanism may further include: the sample rack detector is arranged in the loading buffer area and used for sending a starting signal when detecting that the sample rack is buffered in the loading buffer area;
the loading mechanism is electrically connected with the sample rack detector and used for transferring the sample rack in the loading buffer area to the corresponding detection channel after receiving a starting signal sent by the sample rack detector.
In this embodiment, the sample rack detector may be a camera, a sensor having a shielding detection function, such as a photoelectric gate, or a pressure sensor, and may monitor whether a sample rack is present in a specific area (an area corresponding to the distribution mechanism of the transport mechanism) through the sample detector, and once the sample rack is detected, it indicates that the sample rack is in place, and the sample rack may be transferred from the loading buffer area to the detection channel.
The structures of the internal controllers of the sample analyzer (e.g., CRP analyzer 20), the controllers 61, 62, the main control device 30, and the transmission control device 90 mentioned in the above embodiments are described in detail below, and refer to fig. 13, which is a schematic structural diagram of a data processing device provided in an embodiment of the present application.
The data processing device 110 comprises at least: a processing component 111, a RAM112, a ROM113, a communication interface 114, a memory 116, and an I/O interface 115, wherein the processing component 111, the RAM112, the ROM113, the communication interface 114, the memory 116, and the I/O interface 115 communicate over a bus 117.
The processing component may be a CPU, GPU or other chip with computing capabilities.
The memory 116 stores therein various computer programs such as an operating system and an application program to be executed by the processor element 111, and data necessary for executing the computer programs. In addition, data stored locally during the sample testing process, if desired, may be stored in the memory 116.
The I/O interface 115 is constituted by a serial interface such as USB, IEEE1394, or RS-232C, a parallel interface such as SCSI, IDE, or IEEE1284, and an analog signal interface composed of a D/a converter and an a/D converter. The I/O interface 115 is connected to an input device comprising a keyboard, mouse, touch screen or other control buttons, which a user can use to input data directly to the data processing device 110. In addition, a display having a display function, such as: a liquid crystal screen, a touch screen, an LED display screen, etc., and the data processing device 110 may output the processed data as image display data to a display for displaying, for example: analytical data, instrument operating parameters, etc.
The communication interface 114 is an interface that may be any communication protocol known at the present time. The communication interface 114 communicates with the outside through a network. The data processing apparatus 110 may communicate data with any device connected through the network via the communication interface 114 in a certain communication protocol.
In the embodiment of the present application, the internal controllers of the sample analyzer, the controllers 61 and 62, the main control device 30, and the transmission control device 90 may all adopt the structure of the data processing device 110, and in addition, in consideration of the fact that the controllers 61 and 62 or the transmission control device 90 do not need strong computing power, the data processing device 110 may also only reserve the components for running data and the communication interface, and the I/O interface, for example, may be omitted.
Fig. 14 is a diagram of an implementation scenario of a sample detection system according to an embodiment of the present application.
Referring to fig. 14, a plurality of sample analyzers are included: the blood cell analyzer 10, the CRP analyzer 20, the push-piece stainer 50, and the saccharification instrument 60 are arranged in this order from the beginning to the end in the transport direction X along the transport path.
As shown in fig. 14, the sample detection system may further include: a loading platform 70 and a platform loading mechanism 71, wherein the loading platform 70 is located at one end of the transport path, and the loading platform 70 is used for placing the sample rack. In the embodiment of the present application, the loading platform 70 is located at the front end of the transport direction X of the transport channel, that is, the sample rack is moved from the loading platform 70 to the transport channel, and then is transported to each analyzer through the transport channel. The stage loading mechanism 71 is used to transfer the sample rack on the loading stage 70 to the transfer passage.
In addition, in this embodiment of the present application, the sample detection system further includes: a sample rack detector (not shown), wherein the sample rack detector is disposed on the loading platform 70 and is used for detecting the sample rack on the loading platform 70, and the sample rack detector sends a transfer signal after detecting the sample rack on the loading platform 70. The stage loading mechanism 71 is electrically connected to the sample rack detector, and when the stage loading mechanism 71 receives the transfer signal, the stage loading mechanism 71 transfers the sample rack from the loading stage 70 to the transport path.
As shown in fig. 14, in the embodiment of the present application, the sample detection system further includes: an unloading platform 80 and a platform unloading mechanism 81, wherein the unloading platform 80 is arranged at the other end of the conveying channel, and the unloading platform 80 is used for placing the unloading platform of the sample rack. Referring to embodiment 12, the unloading platform 80 is disposed at the end of the transport path in the transport direction X. When the samples in the sample containers on the sample racks on the transport path are all tested, the sample racks are all transported to the unloading platform 80 for storage. The stage unloading mechanism 81 is used to transfer the sample rack in the transfer lane to the unloading stage 80.
Referring to fig. 14, the feeding mechanisms of the blood cell analyzer 10, the CRP analyzer 20, the slide dyeing machine 50, and the saccharification machine 60 are respectively provided with one controller 61, and all the controllers 61 are connected to a transfer control device 90. In addition, the CRP analyzer 20 is directly connected to its corresponding controller 61, and the controllers 61 corresponding to the blood cell analyzer 10, the slide dyeing machine 50, and the saccharification machine 60 are connected to the main control apparatus 30. The platform loading mechanism and the platform unloading mechanism are also provided with a controller 61 respectively.
In fig. 14, the multi-stage transport mechanism shares one controller 62, and the controller 62 is also connected to a transport control apparatus 90. Of course, in other embodiments, the multi-stage transport mechanism may have separate controllers, or the multi-stage transport mechanism may share one controller 61 with the corresponding feed mechanism.
Through the connection scheme, on one hand, the blood cell analyzer 10, the CRP analyzer 20, the push piece dyeing machine 50 and the saccharification instrument 60 can acquire the fault information of the feeding mechanisms corresponding to the blood cell analyzer through the control 61, and acquire and respectively display the fault information of the transmission mechanisms corresponding to the blood cell analyzer through the control 62, so that the fault information can be locally displayed, and an operator can conveniently and quickly know the fault information in a short distance.
On the other hand, the CRP analyzer 20 controls the feeding mechanism corresponding to the CRP analyzer 20 by the corresponding controller 61. In addition, the main control apparatus 30 controls the feeding mechanisms corresponding to the blood cell analyzer 10, the slide dyeing machine 50, and the saccharification machine 60 by the corresponding controllers 61. Further, the conveyance control device 90 controls the stage loading mechanism 71 and the stage unloading mechanism 81 through the corresponding controllers 61. Therefore, the transport control apparatus 90 can reasonably schedule and control the sample rack in the transport path and in each feeding mechanism when the router 31 acquires the operating state of each instrument.
It is noted that, in this document, relational terms such as "first" and "second," and the like, may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
The foregoing are merely exemplary embodiments of the present invention, which enable those skilled in the art to understand or practice the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (18)

1. A sample detection system, comprising: at least two sample analyzers and a transport device, wherein,
the transmission apparatus includes: the conveying device comprises at least two feeding mechanisms and a plurality of sections of conveying mechanisms, wherein the conveying mechanisms are sequentially connected, and a conveying channel for transferring a sample rack with a sample container is formed between the conveying mechanisms; at least two feeding mechanisms are arranged at intervals along the conveying direction of the conveying channel, and each feeding mechanism is provided with a detection channel;
each sample analyzer corresponds to one feeding mechanism, and the detection area of each sample analyzer corresponds to the detection channel of the corresponding feeding mechanism;
at least one sample analyzer is electrically connected with the corresponding feeding mechanism to acquire and display fault information of the corresponding feeding mechanism.
2. The sample testing system according to claim 1, wherein each of said sample analyzers is electrically connected to a corresponding feed mechanism for obtaining and displaying fault information of the corresponding feed mechanism.
3. The sample detection system according to claim 1 or 2, wherein the at least one sample analyzer comprises a CRP analyzer for detecting C-reactive protein.
4. The sample testing system according to any one of claims 1 to 3, wherein each of said sample analyzers corresponds to at least one of said transport mechanisms;
the at least one sample analyzer is electrically connected with the corresponding transmission mechanism to acquire and display fault information of the transmission mechanism corresponding to the at least one sample analyzer.
5. The sample testing system according to any one of claims 1 to 3, wherein said at least one sample analyzer is electrically connected to a controller of a corresponding feed mechanism and electrically connected to electrical components of the corresponding feed mechanism through said controller, said controller being configured to acquire operating parameters associated with said electrical components;
the controller is further configured to determine fault information from the operating parameters and send the fault information to the at least one sample analyzer; or the controller sends the operation parameters to the at least one sample analyzer, and the at least one sample analyzer determines the fault information of the corresponding feeding mechanism according to the operation parameters.
6. The sample detection system according to any one of claims 1 to 5, wherein the at least one sample analyzer is in direct electrical connection with the electrical components of the corresponding feed mechanism; the at least one sample analyzer receives operating parameters of electrical components connected thereto and determines fault information of a corresponding feed mechanism according to the operating parameters.
7. The sample detection system according to any one of claims 1 to 6, wherein the at least one sample analyzer further comprises: a first operation device for receiving a failure removal operation corresponding to the failure information;
the at least one sample analyzer is further configured to generate and send a fault-handling signal corresponding to the fault-elimination operation to the corresponding feed mechanism and/or transport mechanism.
8. The sample detection system according to any one of claims 1 to 6, wherein the transport apparatus further comprises: a second operating device;
the second operation equipment is electrically connected with the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and is used for receiving the fault elimination operation, generating a fault processing signal corresponding to the fault elimination operation and sending the fault processing signal to the connected feeding mechanism and/or transmission mechanism.
9. The sample testing system according to any one of claims 1-8, wherein said transport apparatus further comprises: a local prompter;
the local prompter is electrically connected with the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and is used for receiving fault information sent by the at least one sample analyzer and/or the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and prompting locally.
10. The sample testing system according to claim 7 or 8, wherein the feeding mechanism corresponding to said at least one sample analyzer and/or the transport mechanism corresponding to said at least one sample analyzer is initialized upon receipt of the failure handling signal.
11. The sample testing system of claim 10, wherein said transmission device further comprises: a sample holder detector;
and the sample rack detector detects whether a sample rack exists on the initialized feeding mechanism and/or the initialized transmission mechanism, and when the sample rack detector does not detect the sample rack, the fault corresponding to the fault processing signal is determined to be eliminated.
12. The sample rack testing system of any of claims 1-9, further comprising: a transmission control device;
the transmission control device is electrically connected with the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer and acquires fault information of the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer, and when the feeding mechanism and/or the transmission mechanism corresponding to the at least one sample analyzer is in fault, the dispatching of the sample rack to the at least one sample analyzer is stopped.
13. The sample detection system according to any one of claims 1-12, wherein the at least one sample analyzer further comprises a first display for displaying the fault information.
14. The sample testing system according to any one of claims 1-13, further comprising: a main control device, wherein,
the at least one sample analyzer is in direct electrical connection with the main control device; the main control equipment is used for acquiring the running state parameters and the fault information of the at least one sample analyzer;
or, the at least one sample analyzer is indirectly electrically connected with the main control device through an intermediate data management device, and the intermediate data management device is used for managing sample data of the sample detection system.
15. The sample testing system according to claim 14, wherein each of said sample analyzers is electrically connected to said main control device, such that said main control device obtains operational status parameters and fault information of each of said sample analyzers.
16. The sample detection system of claim 15, wherein the master control device comprises: a second display, wherein, when the first display is in the first display,
the second display is used for respectively displaying the operation state parameters and the fault information of each sample analyzer in different display areas,
and/or the presence of a gas in the gas,
the second display is used for displaying the fault information of each sample analyzer in different colors.
17. The sample testing system according to any one of claims 1-14, wherein said at least one sample analyzer is connected to a corresponding feed mechanism via a communication link.
18. The sample detection system according to any one of claims 12 to 14, wherein the main control device and the at least one sample analyzer, and the main control device and the transport control device are connected by a communication link.
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