CN112250659B - 一种阿托伐他汀钙中间体的合成方法 - Google Patents
一种阿托伐他汀钙中间体的合成方法 Download PDFInfo
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- CN112250659B CN112250659B CN202011130406.3A CN202011130406A CN112250659B CN 112250659 B CN112250659 B CN 112250659B CN 202011130406 A CN202011130406 A CN 202011130406A CN 112250659 B CN112250659 B CN 112250659B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
- B01J31/06—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides containing polymers
- B01J31/08—Ion-exchange resins
- B01J31/10—Ion-exchange resins sulfonated
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CN202011130406.3A CN112250659B (zh) | 2020-10-21 | 2020-10-21 | 一种阿托伐他汀钙中间体的合成方法 |
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CN202011130406.3A CN112250659B (zh) | 2020-10-21 | 2020-10-21 | 一种阿托伐他汀钙中间体的合成方法 |
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CN112250659A CN112250659A (zh) | 2021-01-22 |
CN112250659B true CN112250659B (zh) | 2021-12-21 |
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1330058A (zh) * | 2000-06-26 | 2002-01-09 | 弗·哈夫曼-拉罗切有限公司 | 制备缩醛和缩酮的方法和装置 |
CN103193972A (zh) * | 2012-01-09 | 2013-07-10 | 烟台万华聚氨酯股份有限公司 | 一种聚醚二元醇的制备方法 |
CN105566281A (zh) * | 2015-02-13 | 2016-05-11 | 江西苏克尔新材料有限公司 | 一种阿托伐他汀钙侧链中间体的制备方法 |
CN107778279A (zh) * | 2017-11-13 | 2018-03-09 | 江苏欧信制药有限公司 | 一种阿托伐他汀钙中间体的制备方法 |
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- 2020-10-21 CN CN202011130406.3A patent/CN112250659B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1330058A (zh) * | 2000-06-26 | 2002-01-09 | 弗·哈夫曼-拉罗切有限公司 | 制备缩醛和缩酮的方法和装置 |
CN103193972A (zh) * | 2012-01-09 | 2013-07-10 | 烟台万华聚氨酯股份有限公司 | 一种聚醚二元醇的制备方法 |
CN105566281A (zh) * | 2015-02-13 | 2016-05-11 | 江西苏克尔新材料有限公司 | 一种阿托伐他汀钙侧链中间体的制备方法 |
CN107778279A (zh) * | 2017-11-13 | 2018-03-09 | 江苏欧信制药有限公司 | 一种阿托伐他汀钙中间体的制备方法 |
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Address after: 223800 No.5 Yanshan Road, eco Chemical Technology Industrial Park, Suqian City, Jiangsu Province Applicant after: Jiangsu alpha Pharmaceutical Co.,Ltd. Address before: 223800 No.5 Yanshan Road, eco Chemical Technology Industrial Park, Suqian City, Jiangsu Province Applicant before: JIANGSU ALPHA PHARMACEUTICAL Co.,Ltd. |
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Denomination of invention: A kind of synthetic method of atorvastatin calcium intermediate Effective date of registration: 20220805 Granted publication date: 20211221 Pledgee: Bank of Jiangsu Co.,Ltd. Suqian Suyu sub branch Pledgor: Jiangsu alpha Pharmaceutical Co.,Ltd. Registration number: Y2022320000440 |
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