CN112204020B - 二氧杂环丁烷化合物及其用于检测微生物的用途 - Google Patents

二氧杂环丁烷化合物及其用于检测微生物的用途 Download PDF

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CN112204020B
CN112204020B CN201980035311.2A CN201980035311A CN112204020B CN 112204020 B CN112204020 B CN 112204020B CN 201980035311 A CN201980035311 A CN 201980035311A CN 112204020 B CN112204020 B CN 112204020B
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formula
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microorganism
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CN112204020A (zh
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D·沙巴特
M·E·罗斯康福特
N·哈纳尼亚
O·格林
U·斯皮茨
L·威克
J·伊森
R·沃伯格
R·柯瑞彪
Z·巴贾科娃
姚春妍
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Nimis Technologies
Ramot at Tel Aviv University Ltd
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Ramot at Tel Aviv University Ltd
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    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
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    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Chemistry (AREA)
CN201980035311.2A 2018-05-25 2019-05-24 二氧杂环丁烷化合物及其用于检测微生物的用途 Active CN112204020B (zh)

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EP18174403 2018-05-25
EP18174403.8 2018-05-25
PCT/EP2019/063418 WO2019224338A1 (en) 2018-05-25 2019-05-24 Dioxetane compounds and their use for the detection of microorganisms

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CN112204020B true CN112204020B (zh) 2023-11-14

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JP (1) JP7462574B2 (enExample)
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Publication number Priority date Publication date Assignee Title
EP3630742B1 (en) * 2017-05-24 2023-08-16 Ramot at Tel-Aviv University Ltd. Chemiluminescent probes for imaging/detection of proteases
WO2021165959A1 (en) * 2020-02-19 2021-08-26 Ramot At Tel-Aviv University Ltd. Chemiluminescence probes for tuberculosis
JP7895730B2 (ja) * 2022-01-28 2026-07-28 シスメックス株式会社 化合物またはその塩、組成物、化学発光方法、化学発光シグナル測定方法、試薬、試薬キットおよび被検物質測定方法
WO2025079067A1 (en) * 2023-10-10 2025-04-17 Ramot At Tel-Aviv University Ltd. Chemiluminescent array-based assay for rapid identification of bacteria and method of use
WO2025191551A1 (en) * 2024-03-13 2025-09-18 Ramot At Tel-Aviv University Ltd. Phenoxy-dioxetanes-based chemiluminescence probes and uses thereof
CN122167488A (zh) * 2024-12-02 2026-06-09 江西科睿药业有限公司 一种抗真菌药物前药、其药物组合物、其中间体、及其制备方法和应用
CN119409748A (zh) * 2025-01-06 2025-02-11 四川省医学科学院·四川省人民医院 一种N-乙酰-β-D-氨基葡萄糖酶的化学发光探针、试剂盒及其制备方法和应用
CN121895281B (zh) * 2026-03-24 2026-06-19 大连理工大学 一种microRNA响应型1,2-二氧杂环丁烷类化学发光化合物、其双探针系统、试剂盒、合成方法及应用

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2017130191A1 (en) * 2016-01-26 2017-08-03 Ramot At Tel-Aviv University Ltd. Chemiluminescent probes for diagnostics and in vivo imaging

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US5223402A (en) 1990-08-30 1993-06-29 Difco Laboratories Method of detecting microbes utilizing chemiluminescent compound
WO2006073424A2 (en) 2004-04-14 2006-07-13 Giri Brij P New ultra-sensitive chemiluminescent substrates for enzymes and their conjugates
WO2009139811A2 (en) 2008-05-15 2009-11-19 Tianxin Wang Chemiluminescent methods and reagents for analyte detection
CN102183512B (zh) 2011-02-15 2012-09-19 杭州师范大学 一种基于化学发光原理的活细胞检测方法
JP2017505612A (ja) 2014-01-17 2017-02-23 ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ メタロ−β−ラクタマーゼを発現する細菌を検出するための６，７−トランスセファロスポリンに基づくプローブ
CN106279178B (zh) 2016-07-18 2019-01-18 华东理工大学 耐碳青霉烯类抗生素病菌的荧光探针及合成方法与应用
EP3630742B1 (en) 2017-05-24 2023-08-16 Ramot at Tel-Aviv University Ltd. Chemiluminescent probes for imaging/detection of proteases

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017130191A1 (en) * 2016-01-26 2017-08-03 Ramot At Tel-Aviv University Ltd. Chemiluminescent probes for diagnostics and in vivo imaging

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US11649475B2 (en) 2023-05-16
EP3802511A1 (en) 2021-04-14
KR20210013620A (ko) 2021-02-04
JP7462574B2 (ja) 2024-04-05
JP2021525273A (ja) 2021-09-24
WO2019224338A1 (en) 2019-11-28
CN112204020A (zh) 2021-01-08
US20230265480A1 (en) 2023-08-24
KR20250052483A (ko) 2025-04-18

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