KR20210013620A - 디옥세탄 화합물 및 미생물의 검출을 위한 이의 용도 - Google Patents
디옥세탄 화합물 및 미생물의 검출을 위한 이의 용도 Download PDFInfo
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- KR20210013620A KR20210013620A KR1020207037220A KR20207037220A KR20210013620A KR 20210013620 A KR20210013620 A KR 20210013620A KR 1020207037220 A KR1020207037220 A KR 1020207037220A KR 20207037220 A KR20207037220 A KR 20207037220A KR 20210013620 A KR20210013620 A KR 20210013620A
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
- C12Q1/10—Enterobacteria
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
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- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
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- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/302—Acyclic unsaturated acids
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- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6551—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a four-membered ring
- C07F9/65512—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a four-membered ring condensed with carbocyclic rings or carbocyclic ring systems
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- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
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- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
- C09K11/06—Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
- C12Q1/045—Culture media therefor
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
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- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
- G01N21/763—Bioluminescence
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- C12Q2304/00—Chemical means of detecting microorganisms
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- General Physics & Mathematics (AREA)
- Emergency Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Chemistry (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020257011217A KR20250052483A (ko) | 2018-05-25 | 2019-05-24 | 디옥세탄 화합물 및 미생물의 검출을 위한 이의 용도 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18174403 | 2018-05-25 | ||
| EP18174403.8 | 2018-05-25 | ||
| PCT/EP2019/063418 WO2019224338A1 (en) | 2018-05-25 | 2019-05-24 | Dioxetane compounds and their use for the detection of microorganisms |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020257011217A Division KR20250052483A (ko) | 2018-05-25 | 2019-05-24 | 디옥세탄 화합물 및 미생물의 검출을 위한 이의 용도 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20210013620A true KR20210013620A (ko) | 2021-02-04 |
Family
ID=62599426
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020207037220A Pending KR20210013620A (ko) | 2018-05-25 | 2019-05-24 | 디옥세탄 화합물 및 미생물의 검출을 위한 이의 용도 |
| KR1020257011217A Pending KR20250052483A (ko) | 2018-05-25 | 2019-05-24 | 디옥세탄 화합물 및 미생물의 검출을 위한 이의 용도 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020257011217A Pending KR20250052483A (ko) | 2018-05-25 | 2019-05-24 | 디옥세탄 화합물 및 미생물의 검출을 위한 이의 용도 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11649475B2 (enExample) |
| EP (1) | EP3802511A1 (enExample) |
| JP (1) | JP7462574B2 (enExample) |
| KR (2) | KR20210013620A (enExample) |
| CN (1) | CN112204020B (enExample) |
| WO (1) | WO2019224338A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3630742B1 (en) * | 2017-05-24 | 2023-08-16 | Ramot at Tel-Aviv University Ltd. | Chemiluminescent probes for imaging/detection of proteases |
| WO2021165959A1 (en) * | 2020-02-19 | 2021-08-26 | Ramot At Tel-Aviv University Ltd. | Chemiluminescence probes for tuberculosis |
| JP7895730B2 (ja) * | 2022-01-28 | 2026-07-28 | シスメックス株式会社 | 化合物またはその塩、組成物、化学発光方法、化学発光シグナル測定方法、試薬、試薬キットおよび被検物質測定方法 |
| WO2025079067A1 (en) * | 2023-10-10 | 2025-04-17 | Ramot At Tel-Aviv University Ltd. | Chemiluminescent array-based assay for rapid identification of bacteria and method of use |
| WO2025191551A1 (en) * | 2024-03-13 | 2025-09-18 | Ramot At Tel-Aviv University Ltd. | Phenoxy-dioxetanes-based chemiluminescence probes and uses thereof |
| CN122167488A (zh) * | 2024-12-02 | 2026-06-09 | 江西科睿药业有限公司 | 一种抗真菌药物前药、其药物组合物、其中间体、及其制备方法和应用 |
| CN119409748A (zh) * | 2025-01-06 | 2025-02-11 | 四川省医学科学院·四川省人民医院 | 一种N-乙酰-β-D-氨基葡萄糖酶的化学发光探针、试剂盒及其制备方法和应用 |
| CN121895281B (zh) * | 2026-03-24 | 2026-06-19 | 大连理工大学 | 一种microRNA响应型1,2-二氧杂环丁烷类化学发光化合物、其双探针系统、试剂盒、合成方法及应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223402A (en) | 1990-08-30 | 1993-06-29 | Difco Laboratories | Method of detecting microbes utilizing chemiluminescent compound |
| WO2006073424A2 (en) | 2004-04-14 | 2006-07-13 | Giri Brij P | New ultra-sensitive chemiluminescent substrates for enzymes and their conjugates |
| WO2009139811A2 (en) | 2008-05-15 | 2009-11-19 | Tianxin Wang | Chemiluminescent methods and reagents for analyte detection |
| CN102183512B (zh) | 2011-02-15 | 2012-09-19 | 杭州师范大学 | 一种基于化学发光原理的活细胞检测方法 |
| JP2017505612A (ja) | 2014-01-17 | 2017-02-23 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | メタロ−β−ラクタマーゼを発現する細菌を検出するための6,7−トランスセファロスポリンに基づくプローブ |
| CN108884386B (zh) * | 2016-01-26 | 2022-03-15 | 特拉维夫大学拉玛特有限公司 | 用于诊断和体内成像的化学发光探针 |
| CN106279178B (zh) | 2016-07-18 | 2019-01-18 | 华东理工大学 | 耐碳青霉烯类抗生素病菌的荧光探针及合成方法与应用 |
| EP3630742B1 (en) | 2017-05-24 | 2023-08-16 | Ramot at Tel-Aviv University Ltd. | Chemiluminescent probes for imaging/detection of proteases |
-
2019
- 2019-05-24 EP EP19728340.1A patent/EP3802511A1/en active Pending
- 2019-05-24 KR KR1020207037220A patent/KR20210013620A/ko active Pending
- 2019-05-24 WO PCT/EP2019/063418 patent/WO2019224338A1/en not_active Ceased
- 2019-05-24 JP JP2020567041A patent/JP7462574B2/ja active Active
- 2019-05-24 KR KR1020257011217A patent/KR20250052483A/ko active Pending
- 2019-05-24 CN CN201980035311.2A patent/CN112204020B/zh active Active
- 2019-05-24 US US17/058,623 patent/US11649475B2/en active Active
-
2023
- 2023-03-15 US US18/184,249 patent/US20230265480A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20210214766A1 (en) | 2021-07-15 |
| US11649475B2 (en) | 2023-05-16 |
| EP3802511A1 (en) | 2021-04-14 |
| JP7462574B2 (ja) | 2024-04-05 |
| JP2021525273A (ja) | 2021-09-24 |
| WO2019224338A1 (en) | 2019-11-28 |
| CN112204020A (zh) | 2021-01-08 |
| CN112204020B (zh) | 2023-11-14 |
| US20230265480A1 (en) | 2023-08-24 |
| KR20250052483A (ko) | 2025-04-18 |
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