CN112190677A - Traditional Chinese medicine composition for treating epigastric pain, traditional Chinese medicine plaster and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating epigastric pain, traditional Chinese medicine plaster and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating epigastric pain, a traditional Chinese medicine plaster and a preparation method thereof, wherein the traditional Chinese medicine composition comprises the following components in parts by weight: 5-20 parts of galangal, 5-20 parts of cinnamon, 5-20 parts of round cardamom, 5-20 parts of rhizoma corydalis, 5-20 parts of aspongopus, 5-20 parts of fennel, 5-20 parts of evodia rutaecarpa, 5-20 parts of clove, 5-20 parts of cubeb, 5-20 parts of notopterygium, 20-40 parts of white paeony root, 5-20 parts of French sea and 5-20 parts of rhizoma cyperi. The traditional Chinese medicine composition can effectively solve the problem of poor treatment effect caused by bitter taste and incapability of persisting in patients when the traditional Chinese medicine is taken orally.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicine compositions, and in particular relates to a traditional Chinese medicine composition for treating epigastric pain, a traditional Chinese medicine plaster and a preparation method thereof.
Background
Stomachache: it is also called epigastric pain, for the syndrome of stomach ache difficult to endure and pain in the epigastric region caused by the impairment of spleen and stomach and the disharmony of qi and blood.
Common causes of stomach ache include stomach cold, stomach impairment due to food and drink, stomach invasion due to liver-qi, and weakness of spleen and stomach. The stomach is mainly used for receiving rotten food, and if cold pathogen is in the stomach, cold congealing can not disperse, and qi movement is blocked, so that stomach qi can be discordant and pain, or stomach qi can be discordant and hungry due to improper diet, or overeating, fat and sweet food, indigestion, qi movement is blocked, and stomach disorder and descending can cause stomach pain; the liver has the function of smoothing flow of qi and relieving the flow of qi of the spleen and stomach, such as stomachache caused by anger depression, liver injury due to qi depression, liver dysfunction, transverse reflux and stomach invasion; if the patient suffers from internal injury due to overstrain, weakness of spleen and stomach due to long-term illness, or deficiency of innate essence, deficiency of middle-jiao, stomach failing to warm and nourish, internal cold breeding, and pain due to deficiency-cold of middle-jiao; there are also stomach ache attacks caused by long-term qi stagnation, blood stasis, qi stagnation and blood stasis obstructing qi movement of middle energizer. In a word, the pathogenesis of stomachache is divided into two ends of deficiency and excess, the excess syndrome is qi stagnation, and obstruction leads to pain; the deficiency syndrome refers to the condition of stomach failing to warm or nourish the stomach, which leads to pain.
In the prior art, stomachache caused by qi stagnation, cold stagnation and other causes is generally treated by oral medicines, the oral medicines are divided into chemical medicines and traditional Chinese medicines, the chemical medicines generally contain components for relieving pain and promoting gastrointestinal peristalsis, and can only relieve stomachache symptoms from the surface, but cannot realize the functions of regulating qi and dispelling cold; although the traditional Chinese medicine can be used for targeted treatment of qi stagnation and cold stagnation, the traditional Chinese medicine is bitter in taste and slow in treatment effect, and many patients cannot insist on taking the traditional Chinese medicine, so that the stomachache cannot be treated well and cannot be cured radically.
Disclosure of Invention
Aiming at the defects in the prior art, the invention provides a traditional Chinese medicine composition for treating epigastric pain, a traditional Chinese medicine plaster and a preparation method thereof.
In order to achieve the purpose, the technical scheme adopted by the invention for solving the technical problems is as follows:
a traditional Chinese medicine composition for treating epigastric pain comprises the following components in parts by weight: 5-20 parts of galangal, 5-20 parts of cinnamon, 5-20 parts of round cardamom, 5-20 parts of rhizoma corydalis, 5-20 parts of aspongopus, 5-20 parts of fennel, 5-20 parts of evodia rutaecarpa, 5-20 parts of clove, 5-20 parts of cubeb, 5-20 parts of notopterygium, 20-40 parts of white paeony root, 5-20 parts of French sea and 5-20 parts of rhizoma cyperi.
Further, the paint comprises the following components in parts by weight: 5-10 parts of galangal, 5-10 parts of cinnamon, 5-10 parts of round cardamom, 5-10 parts of rhizoma corydalis, 5-10 parts of aspongopus, 5-10 parts of fennel, 5-10 parts of evodia rutaecarpa, 5-10 parts of clove, 5-10 parts of cubeb, 5-10 parts of notopterygium, 25-35 parts of white paeony root, 15-20 parts of French sea and 10-20 parts of rhizoma cyperi.
Further, the paint comprises the following components in parts by weight: 10 parts of galangal, 10 parts of cinnamon, 10 parts of cardamom, 10 parts of rhizoma corydalis, 10 parts of aspongopus, 10 parts of fennel, 10 parts of evodia rutaecarpa, 10 parts of clove, 10 parts of cubeb, 10 parts of notopterygium, 30 parts of white peony root, 15 parts of French sea and 15 parts of cyperus rotundus.
In the scheme, the galangal is pungent and hot in nature, enters spleen and stomach channels, has the effects of dispelling heat, dredging, dispelling cold and relieving pain, the rhizoma cyperi is pungent, slightly bitter and slightly sweet in nature, enters liver and spleen channels, has the effects of promoting qi circulation, regulating menstruation and relieving pain, the radix paeoniae alba is bitter, sour and slightly cold in nature, enters liver and spleen channels, has the effects of nourishing yin, calming liver and relieving pain, the rhizoma salviae is pungent and bitter in nature, enters spleen and liver and lung channels, and has the effects of regulating qi and relieving pain, the four medicaments can act on lung channels, spleen and stomach channels and liver channels after being used together, the lung governs qi of the whole body, the waste is disordered and descended, so that qi stagnation is easy to appear, and the pain is caused by qi stagnation; the galangal, the rhizoma cyperi, the white paeony root and the faluohai are used together to respectively act with the liver, the spleen and the stomach and the lung channels to promote the functions of the liver, the spleen and the stomach and the lung, dredge and transmit qi movement and food essence in the body, realize smooth qi movement and further improve the stomachache symptoms caused by qi movement blockage.
The notopterygium root enters liver and stomach meridians and has the functions of promoting qi circulation and relieving pain, and the aspongopus enters liver, kidney and spleen meridians and has the functions of promoting qi circulation and relieving pain; the Qiang live fish and the aspongopus have the functions of promoting qi circulation, strengthening the dredging of qi activity and promoting qi circulation to relieve pain.
Cinnamon is pungent, sweet and hot in nature and has the functions of tonifying fire, supporting yang, dispelling cold, relieving pain, activating blood circulation and stimulating the menstrual flow, clove is pungent, sweet and hot in nature and has the functions of tonifying fire and supporting yang, kidney, spleen, heart and liver channels, and cubeb is pungent and warm in nature and has the functions of warming spleen, stomach, kidney and bladder channels, promoting qi circulation and relieving pain and drying dampness; the fennel has pungent and warm natured flavor, enters liver, kidney, spleen and stomach channels, has the functions of regulating qi, dispelling cold and supporting yang, and the evodia rutaecarpa has pungent, bitter and warm natured flavor, enters liver and stomach channels, and has the functions of warming middle-jiao, regulating qi and drying dampness. In the medicines, the evodia and the cubeb have the function of drying dampness and are used for removing in-vivo moisture, and the cinnamon, the clove and the fennel have the functions of dispelling cold, relieving pain, tonifying fire and supporting yang.
The cardamom has pungent and warm natures, enters the lung, spleen and stomach meridians, has the functions of regulating qi, relieving epigastric distention, promoting qi circulation, warming the middle energizer and dispelling cold, the rhizoma corydalis has pungent, bitter and warm natures, enters the heart, spleen, liver and lung meridians, has the functions of promoting blood circulation, removing blood stasis, promoting qi circulation and relieving pain, and the purpose of relieving pain is realized by the functions of harmonizing the stomach, promoting qi circulation and dispelling cold after the cardamom and the rhizoma corydalis are used together.
The medicines are combined to mutually coordinate, so that the aim of treating the epigastric pain is fulfilled through the functions of regulating qi, promoting qi circulation, dispelling cold, harmonizing stomach and warming, the functions of all internal organs of a patient are fundamentally conditioned, and the aim of treating both principal and secondary aspect of disease is fulfilled.
A Chinese medicinal patch for treating gastralgia is prepared from the Chinese medicinal composition and oleum Cinnamomi.
The preparation method of the traditional Chinese medicine application for treating epigastric pain comprises the following steps:
(1) pulverizing the Chinese medicinal composition, and sieving to obtain Chinese medicinal powder;
(2) sterilizing the traditional Chinese medicine powder in the step (1) at high temperature to obtain sterile powder;
(3) adding cinnamon oil into the sterile powder obtained in the step (2), mixing into paste, and placing the paste mixture on a plaster to prepare the dressing.
Further, the particle size of the traditional Chinese medicine powder is 200 meshes.
Further, the step (2) is carried out for 30-60min at the temperature of 100-120 ℃.
In the scheme, the prepared dressing is applied to abdominal acupuncture points of a patient, the medicine enters meridians and collaterals through skin striae, is conducted through meridians and collaterals, and quickly plays a role, and is conducted to organs such as liver, lung, spleen and stomach through meridians and collaterals, so that the corresponding functions of each viscera are improved, the viscera are enabled to recover normal functions, and the aim of treating epigastric pain is fundamentally achieved.
The beneficial effects produced by the invention are as follows: the formula of the traditional Chinese medicine composition is scientific and reasonable, different medicines are matched and cooperated with each other, and the combined medicines achieve the purpose of treating the epigastric pain through the effects of promoting qi circulation to relieve pain, dispelling cold to relieve pain, warming the abdomen to relieve pain and harmonizing the stomach to relieve pain.
The Chinese medicinal composition is ground into powder, is blended into paste through cinnamon oil, is prepared into a plaster, is externally applied to acupuncture points of a patient to play a role in treatment, is hot in cinnamon oil, accelerates the medicament to enter the body through skin striae after being applied, and quickly conducts the medicament entering the body to organs of various internal organs through meridians and collaterals to restore the functions of the various internal organs and play a corresponding role in treatment. The composition exerts drug effect in the form of external application, achieves the purpose of treatment, can greatly reduce the feeling of conflict of a patient on traditional Chinese medicines, and improves the treatment experience of the patient.
Detailed Description
Example 1
A traditional Chinese medicine composition for treating epigastric pain comprises the following components in parts by weight: 10 parts of galangal, 10 parts of cinnamon, 15 parts of cardamom, 15 parts of rhizoma corydalis, 10 parts of aspongopus, 10 parts of fennel, 10 parts of evodia rutaecarpa, 150 parts of clove, 150 parts of cubeb, 150 parts of notopterygium, 30 parts of white paeony root, 10 parts of French sea and 10 parts of cyperus rotundus.
A traditional Chinese medicine plaster for treating epigastric pain is prepared by the following steps:
(1) pulverizing the Chinese medicinal composition, and sieving to obtain Chinese medicinal powder with particle size of 200 meshes;
(2) treating the traditional Chinese medicine powder in the step (1) at 100 ℃ for 30min for high-temperature sterilization and disinfection to obtain sterile powder;
(3) adding cinnamon oil into the sterile powder obtained in the step (2), mixing into paste, and placing the paste mixture on a plaster to prepare the dressing.
Example 2
A traditional Chinese medicine composition for treating epigastric pain comprises the following components in parts by weight: 20 parts of galangal, 10 parts of cinnamon, 20 parts of cardamom, 10 parts of rhizoma corydalis, 10 parts of aspongopus, 20 parts of fennel, 20 parts of evodia rutaecarpa, 20 parts of clove, 10 parts of cubeb, 15 parts of notopterygium, 20 parts of white peony root, 10 parts of French sea and 10 parts of cyperus rotundus.
A traditional Chinese medicine plaster for treating epigastric pain is prepared by the following steps:
(1) pulverizing the Chinese medicinal composition, and sieving to obtain Chinese medicinal powder with particle size of 200 meshes;
(2) treating the traditional Chinese medicine powder in the step (1) at 120 ℃ for 40min for high-temperature sterilization and disinfection to obtain sterile powder;
(3) adding cinnamon oil into the sterile powder obtained in the step (2), mixing into paste, and placing the paste mixture on a plaster to prepare the dressing.
Example 3
A traditional Chinese medicine composition for treating epigastric pain comprises the following components in parts by weight: 10 parts of galangal, 10 parts of cinnamon, 10 parts of cardamom, 10 parts of rhizoma corydalis, 10 parts of aspongopus, 10 parts of fennel, 10 parts of evodia rutaecarpa, 10 parts of clove, 10 parts of cubeb, 10 parts of notopterygium, 30 parts of white peony root, 15 parts of French sea and 15 parts of cyperus rotundus.
A traditional Chinese medicine plaster for treating epigastric pain is prepared by the following steps:
(1) pulverizing the Chinese medicinal composition, and sieving to obtain Chinese medicinal powder with particle size of 200 meshes;
(2) treating the traditional Chinese medicine powder in the step (1) at 110 ℃ for 50min for high-temperature sterilization and disinfection to obtain sterile powder;
(3) adding cinnamon oil into the sterile powder obtained in the step (2), mixing into paste, and placing the paste mixture on a plaster to prepare the dressing.
Comparative example 1
A traditional Chinese medicine composition for treating epigastric pain comprises the following components in parts by weight: 10 parts of folium artemisiae argyi, 10 parts of cinnamon, 10 parts of cardamom, 10 parts of rhizoma corydalis, 10 parts of szechwan chinaberry fruit, 10 parts of common fennel, 10 parts of officinal magnolia bark, 10 parts of clove, 10 parts of cubeb, 10 parts of notopterygium, 30 parts of white paeony root, 15 parts of French sea and 15 parts of common monkshood daughter root.
A traditional Chinese medicine plaster for treating epigastric pain is prepared by the following steps:
(1) pulverizing the Chinese medicinal composition, and sieving to obtain Chinese medicinal powder with particle size of 200 meshes;
(2) treating the traditional Chinese medicine powder in the step (1) at 110 ℃ for 50min for high-temperature sterilization and disinfection to obtain sterile powder;
(3) adding cinnamon oil into the sterile powder obtained in the step (2), mixing into paste, and placing the paste mixture on a plaster to prepare the dressing.
Comparative example 2
A traditional Chinese medicine composition for treating epigastric pain comprises the following components in parts by weight: 10 parts of galangal, 10 parts of cinnamon, 10 parts of cardamom, 10 parts of rhizoma corydalis, 10 parts of aspongopus, 10 parts of fennel, 10 parts of evodia rutaecarpa, 10 parts of clove, 10 parts of cubeb, 10 parts of costus root, 30 parts of keel, 15 parts of falia and 15 parts of loofah sponge.
A traditional Chinese medicine plaster for treating epigastric pain is prepared by the following steps:
(1) pulverizing the Chinese medicinal composition, and sieving to obtain Chinese medicinal powder with particle size of 200 meshes;
(2) treating the traditional Chinese medicine powder in the step (1) at 110 ℃ for 50min for high-temperature sterilization and disinfection to obtain sterile powder;
(3) adding cinnamon oil into the sterile powder obtained in the step (2), mixing into paste, and placing the paste mixture on a plaster to prepare the dressing.
Comparative example 3
A traditional Chinese medicine composition for treating epigastric pain comprises the following components in parts by weight: 10 parts of dried ginger, 10 parts of cinnamon, 10 parts of cardamom, 10 parts of rhizoma corydalis, 10 parts of aspongopus, 10 parts of fennel, 10 parts of evodia rutaecarpa, 10 parts of clove, 10 parts of cubeb, 10 parts of notopterygium, 15 parts of tangerine seed and 15 parts of cyperus rotundus.
A traditional Chinese medicine plaster for treating epigastric pain is prepared by the following steps:
(1) pulverizing the Chinese medicinal composition, and sieving to obtain Chinese medicinal powder with particle size of 200 meshes;
(2) treating the traditional Chinese medicine powder in the step (1) at 110 ℃ for 50min for high-temperature sterilization and disinfection to obtain sterile powder;
(3) adding cinnamon oil into the sterile powder obtained in the step (2), mixing into paste, and placing the paste mixture on a plaster to prepare the dressing.
Test examples
The traditional Chinese medicine composition in the examples 1-3 and the traditional Chinese medicine composition in the comparative examples 1-3 are randomly searched for 60 patients frequently suffering from epigastric pain, the patients are randomly divided into 6 groups, 10 patients in each group are respectively used for 6 groups of patients, the patients begin to be pasted when suffering from epigastric pain, the pasting positions are Shenque point, Zhongwan point and Guanyuan point, the symptoms after the pasting are observed and recorded, the patients are used for 1 time every day and 6 hours every time for 5 days continuously, and then the condition of the epigastric pain of the patients is observed and recorded, and the specific results are shown in tables 1-2.
Evaluation criteria:
and (3) curing: the epigastric pain symptoms disappear;
the method has the following advantages: relief of epigastric pain symptoms;
and (4) invalidation: epigastric pain symptoms are not improved;
table 1: first treatment statistical table
As can be seen from the above table, the traditional Chinese medicine composition in the embodiment 1-3 of the invention can rapidly and effectively relieve the stomachache symptom of the patient, while the traditional Chinese medicine composition in the comparative example 1-3 has a poorer effect in relieving the stomachache symptom than the embodiment 1-3, which proves that the traditional Chinese medicine composition in the invention has the mutual effect of exerting the drug effect, and the collocation of the composition is more scientific and reasonable.
Table 2: statistical table of cure rate
As can be seen from the above table, the traditional Chinese medicine composition in the examples 1-3 of the invention has better treatment effect and higher cure rate, while the traditional Chinese medicine composition in the comparative examples 1-3 has far worse treatment effect than the traditional Chinese medicine composition in the examples 1-3.
The traditional Chinese medicine compositions in the comparative examples 1, 2 and 3 are respectively compared with the traditional Chinese medicine composition in the example 3, the treatment effect of the comparative example 1 is poor after the galangal is replaced by the folium artemisiae argyi with similar effect, the aspongopus is replaced by the toosendan fruit with similar effect, and the evodia rutaecarpa is replaced by the magnolia officinalis with similar effect, so that the traditional Chinese medicine composition in the example 3 is proved to have interaction, and although part of medicinal materials are replaced by the medicines with similar effect, the collocation effect of the medicines is obviously poor.
In the comparative example 2, notopterygium root is replaced by costus root with similar effect, white peony root is replaced by dragon bone with similar effect, and nutgrass galingale rhizome is replaced by luffa with similar effect, the treatment effect of the comparative example 2 is poor, and the traditional Chinese medicine composition in the example 3 is proved to have interaction, and although part of medicinal materials are replaced by medicines with similar effect, the matching effect of the medicines is obviously poor.
In the comparative example 3, the addition of white paeony root is cancelled, galangal is replaced by dried ginger with similar effect, and the French sea is replaced by tangerine seed with similar effect, so that the treatment effect of the comparative example 3 is poor, and the traditional Chinese medicine composition in the example 3 is proved to have interaction, and although partial medicinal materials are replaced by the medicines with similar effect, the matching effect of the medicines is obviously poor.
Claims (7)
1. The traditional Chinese medicine composition for treating epigastric pain is characterized by comprising the following components in parts by weight: 5-20 parts of galangal, 5-20 parts of cinnamon, 5-20 parts of round cardamom, 5-20 parts of rhizoma corydalis, 5-20 parts of aspongopus, 5-20 parts of fennel, 5-20 parts of evodia rutaecarpa, 5-20 parts of clove, 5-20 parts of cubeb, 5-20 parts of notopterygium, 20-40 parts of white paeony root, 5-20 parts of French sea and 5-20 parts of rhizoma cyperi.
2. The traditional Chinese medicine composition for treating epigastric pain according to claim 1, which comprises the following components in parts by weight: 5-10 parts of galangal, 5-10 parts of cinnamon, 5-10 parts of round cardamom, 5-10 parts of rhizoma corydalis, 5-10 parts of aspongopus, 5-10 parts of fennel, 5-10 parts of evodia rutaecarpa, 5-10 parts of clove, 5-10 parts of cubeb, 5-10 parts of notopterygium, 25-35 parts of white paeony root, 15-20 parts of French sea and 10-20 parts of rhizoma cyperi.
3. The traditional Chinese medicine composition for treating epigastric pain according to claim 1, which comprises the following components in parts by weight: 10 parts of galangal, 10 parts of cinnamon, 10 parts of cardamom, 10 parts of rhizoma corydalis, 10 parts of aspongopus, 10 parts of fennel, 10 parts of evodia rutaecarpa, 10 parts of clove, 10 parts of cubeb, 10 parts of notopterygium, 30 parts of white peony root, 15 parts of French sea and 15 parts of cyperus rotundus.
4. A Chinese medicinal patch for treating gastralgia is prepared from the Chinese medicinal composition of any one of claims 1-3 and oleum Cinnamomi.
5. The preparation method of the Chinese medicinal patch for treating epigastric pain as claimed in claim 4, comprising the steps of:
(1) pulverizing the Chinese medicinal composition, and sieving to obtain Chinese medicinal powder;
(2) sterilizing the traditional Chinese medicine powder in the step (1) at high temperature to obtain sterile powder;
(3) adding cinnamon oil into the sterile powder obtained in the step (2), mixing into paste, and placing the paste mixture on a plaster to prepare the dressing.
6. The method for preparing a Chinese medicinal patch for the treatment of epigastric pain as claimed in claim 5, wherein the particle size of said Chinese medicinal powder is 200 mesh.
7. The method for preparing a Chinese medicinal patch for the treatment of epigastric pain as claimed in claim 5, wherein the step (2) is carried out at 100-120 ℃ for 30-60 min.
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| CN112138047A (en) * | 2020-10-29 | 2020-12-29 | 杨玉良 | Traditional Chinese medicine composition with functions of warming yang and tonifying kidney, traditional Chinese medicine plaster and preparation method thereof |
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