CN103356948A

CN103356948A - Drug for treating stomachache, and preparation method thereof

Info

Publication number: CN103356948A
Application number: CN2013103277257A
Authority: CN
Inventors: 赵军海
Original assignee: 赵军海
Current assignee: Wang Huailan
Priority date: 2013-07-31
Filing date: 2013-07-31
Publication date: 2013-10-23
Anticipated expiration: 2033-07-31
Also published as: CN103356948B

Abstract

The invention discloses a drug for treating stomachache, and a preparation method thereof. The drug for treating stomachache comprises the following components by weight: 10-40 parts of herba artemisiae scopariae, 10-30 parts of rhizoma alpiniae officinarum, 10-40 parts of rhizoma cyperi, 10-40 parts of fructus evodiae, 10-50 parts of dried orange peel, 10-40 parts of fructus aurantii immaturus, 15-50 parts of medicated leaven, 10-40 parts of largehead atractylodes rhizome, 3-30 parts of fingered citron, 6-40 parts of cuttlebone, 6-30 parts of white paeony root, 6-40 parts of amomum cardamomum, 6-30 parts of rhizoma corydalis and 3-20 parts of coptidis rhizome. The drug is prepared by the steps of washing the above components clean, drying at a low temperature of 40-55 DEG C, smashing the dried components, screening the smashed components with a 100-mesh sieve, sterilizing by ultraviolet radiation, and preparing into capsules. The drug provided by the invention is safe and non-toxic, has no side effect, is convenient for use, is suitable for various diseases of the stomachache, has significant curative effect, is not easy to relapse, and has popularization and application values.

Description

A kind of medicine for the treatment of stomachache and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of stomachache and preparation method thereof.

Background technology

Stomachache is because taste are impaired, and qi and blood disorder causes that stomachache is hard to bear, gastral cavilty section pain.

The main clinical manifestation of stomachache has, and can involve the side of body back of the body during pain, or double breast wrist painful abdominal mass is vexed, nausea and vomiting, and poor appetite, belch, or acid regurgitation, or vomiting watery fluid etc.; And the common cause that stomachache occurs has cold-evil visitor stomach, and diet injures one's stomach, hyperactive liver-QI attacking the stomach, the several aspects of weakness of the spleen and stomach.

Show that after deliberation the incidence rate of chronic atrophic gastritis and gastric cancer is proportional, and gastric cancer to be M ﹠ M in China occupy first of all kinds of tumors, so, treatment stomachache how timely, the generation of prophylaxis of cancer is a domestic and international focus of research always.

The medicine for the treatment of stomachache commonly used mainly take Western medicine as main, perhaps comes alleviating pain by the mode of having an intravenous drip at present, ubiquity is cured the symptoms, not the disease, and effects a radical cure not thoroughly, even the shortcoming of certain side effect is arranged, up to the present, there is no clinically the medicine of satisfied treatment stomachache.

Summary of the invention

The purpose of this invention is to provide a kind of medicine for the treatment of stomachache and preparation method thereof.

The present invention is achieved by the following technical solutions:

A kind of medicine for the treatment of stomachache comprises each component of following weight portion:

Rhizoma Alpiniae Officinarum 5～40 Rhizoma Cyperis 10～40 Fructus Evodiaes 10～40

Pericarpium Citri Reticulatae 10～50 Fructus Aurantii Immaturuss 10～40 Massa Medicata Fermentata 15～50

Rhizoma Atractylodis Macrocephalae (parched) 10～40 Fructus Citri Sarcodactylis 3～30 Os Sepiae 6～40

The Radix Paeoniae Alba 6～30 Fructus Amomi Rotunduss 6～40 Rhizoma Corydalis 6～30

Rhizoma Coptidis 3～20.

Further, each component of the preferred following weight portion of the present invention:

Rhizoma Alpiniae Officinarum 20 Rhizoma Cyperis 25 Fructus Evodiaes 30

Pericarpium Citri Reticulatae 30 Fructus Aurantii Immaturuss 30 Massa Medicata Fermentata 30

Rhizoma Atractylodis Macrocephalae (parched) 30 Fructus Citri Sarcodactylis 18 Os Sepiae 25

The Radix Paeoniae Alba 15 Fructus Amomi Rotunduss 18 Rhizoma Corydalis 15

Rhizoma Coptidis 12.

During preparation, after above-mentioned weight portion rinsing totally, 100 mesh sieves were pulverized in cold drying under 40-55 ℃ of condition, made capsule behind ultraviolet radiation sterilization.

Medicine of the present invention is pale yellow powder, mildly bitter flavor; During use, should be in bfore meals, three times on the one, oral one time 5; But warming spleen and stomach for dispelling cold, regulating QI to relieve pain, to the acute and chronic stomachache, flatulence has significant effect.

Medicine Rhizoma Alpiniae Officinarum acrid in the mouth of the present invention is hot in nature, warming the middle warmer and descending qi is arranged, the effect that pain relieving helps digestion; The little hardship of Rhizoma Cyperi acrid in the mouth, property is flat, and the effect of the resolving depression of regulating the flow of vital energy is arranged, and is usually used in breast side of body wrist abdominal distention and pain; The Fructus Evodiae acrid in the mouth is bitter, and is hot in nature, slightly poisonous, warming stomach for dispelling cold arranged, the effect of sending down the abnormal ascending QI pain relieving; The Pericarpium Citri Reticulatae acrid in the mouth is bitter, and is warm in nature, regulating qi-flowing for strengthening spleen arranged, the effect of drying dampness to eliminate phlegm; The acid of Fructus Aurantii Immaturus bitter in the mouth, cold nature eliminates indigestion and phlegm, the effect of circulation of qi promoting removing mass; The Massa Medicata Fermentata acrid-sweet flavor, warm in nature, the mouth that can whet the appetite is promoted diet; The Rhizoma Atractylodis Macrocephalae (parched) sweet-bitter flavor, slightly warm in nature has tonifying the spleen and stomach, the effect of dampness; The Os Sepiae puckery is salty, and is warm in nature, and the effect of astringing to arrest bleeding antacid leukorrhagia stopping is arranged; The Fructus Amomi Rotundus acrid in the mouth, warm in nature, energy circulation of qi promoting warming middle-JIAO, cold expelling dampness, appetite-stimulating indigestion-relieving; Fructus Citri Sarcodactylis acrid in the mouth picric acid, warm in nature, dispersing the stagnated live-QI to relieve the stagnation of QI is arranged, the effect of the chest stuffiness relieving of regulating the flow of vital energy; Radix Paeoniae Alba sour in the mouth is bitter, and cold nature has the effect of convergence and replenishing YIN and blood; The Rhizoma Corydalis acrid in the mouth is bitter, and is warm in nature, promoting flow of QI and blood arranged, the effect of eliminating stasis to stop pain; The Rhizoma Coptidis bitter in the mouth, cold in nature, the effect of heat clearing and damp drying is arranged; After above-mentioned each crude drug mixed according to aforementioned proportion, has the effect of warming spleen and stomach for dispelling cold, depressed liver-energy dispersing and QI regulating pain relieving, the stomach function regulating that expels the heat-evil.

In order to verify the curative effect of medicine of the present invention, carried out following test:

One, case is selected: choose the age in clinical case 100 examples with stomachache symptom in 22-78 year, women 36 examples wherein, male 64 examples; Disease all is the symptom of stomachache, wherein feeling of fullness 22 examples, pantothenic acid 14 examples, gastral cavilty section pain 35 examples, nausea and vomiting 15 examples, heating installation 14 examples.

Two, Therapeutic Method: take three months as a course for the treatment of,

Matched group: use " stomach-recovering capsule " 4 of one after each meals one time, 3 times on the one;

Treatment group: take medicine of the present invention, bfore meals, three times on the one, one time five.

Three, treatment index:

Clinical symptoms: record once comprises patient's body of the tongue, tongue fur, pulse condition, weak, pantothenic acid, stomachache, feeling of fullness weekly;

Gastroscopy: gastric mucosa color, blood vessel are seen thoroughly, extent of disease.

Four, therapeutic outcome: according to " the gastric abscess diagnosis of Society of Internal Medicine of All-China Association of Traditional Chinese Medicine, efficacy assessment standard ", wherein invalid: cardinal symptom is unchanged, and corresponding major event physico-chemical examination is unchanged; Take a turn for the better: the cardinal symptom elimination, though in 6 months to 1 year outbreak is arranged, pain relief, the persistent period shortens, and corresponding major event physico-chemical examination changes little; Produce effects: cardinal symptom is eliminated, and does not recur in 6 months to 1 year, and corresponding major event physico-chemical examination takes a turn for the better, and improves with reference to symptom, sign; Recovery from illness: symptom all disappears, and does not recur in 6 months to 1 year, and corresponding major event physico-chemical examination substantially recovers normally or takes a turn for the better to some extent, recovers such as ordinary person with reference to symptom and sign.

According to above-mentioned standard, therapeutic outcome is as shown in table 1,

Table 1

Group	The example number	Recovery from illness	Produce effects	Take a turn for the better	Invalid	Effective percentage
							Matched group	100	42	31	15	12	88%
Treatment group	100	61	24	11	4	96%

As can be seen from Table 1, medicine of the present invention has significant curative effect than existing medicine to stomachache, can reach 96%.

Safety of medicine of the present invention is nontoxic, have no side effect, and easy to use, the various diseases that are applicable to have a stomachache have significant curative effect, and are difficult for recurrence, have popularizing value.

The specific embodiment

Below in conjunction with specific embodiment medicine of the present invention is described further.

Embodiment 1

Get Rhizoma Alpiniae Officinarum 20g, Rhizoma Cyperi 25g, Fructus Evodiae 30g, Pericarpium Citri Reticulatae 30g, Fructus Aurantii Immaturus 30g, Massa Medicata Fermentata 30g, Rhizoma Atractylodis Macrocephalae (parched) 30g, Fructus Citri Sarcodactylis 18g, Os Sepiae 25g, Radix Paeoniae Alba 15g, Fructus Amomi Rotundus 18g, Rhizoma Corydalis 15g, Rhizoma Coptidis 12g, after rinsing is clean, cold drying under 40-55 ℃ of condition, pulverize 100 mesh sieves, behind ultraviolet radiation sterilization, made capsule.

Su Lizhi, the man, 40 years old, the patient had a stomachache for many years, aversion to cold happiness is warm, the wrist distention and fullness in the abdomen, belching and acid regurgitation, the time tell indigestion food, it is not good to eat the multiple medicines effect, takes said medicine after two months, symptom disappears substantially, takes one month with follow-up, consolidates curative effect, so far without recurring.

Embodiment 2

Get Rhizoma Alpiniae Officinarum 5g, Rhizoma Cyperi 33g, Fructus Evodiae 40g, Pericarpium Citri Reticulatae 10g, Fructus Aurantii Immaturus 40g, Massa Medicata Fermentata 40g, Rhizoma Atractylodis Macrocephalae (parched) 20g, Fructus Citri Sarcodactylis 30g, Os Sepiae 6g, Radix Paeoniae Alba 25g, Fructus Amomi Rotundus 6g, Rhizoma Corydalis 22g, Rhizoma Coptidis 3g, after rinsing is clean, cold drying under 40-55 ℃ of condition, pulverize 100 mesh sieves, behind ultraviolet radiation sterilization, made capsule.

Jiang Xinping, the man, 51 years old, the Stomach in Patients pain with distension was vexed, stomachache connects the side of body, belch is frequent, it is not smooth defecate, take medicine of the present invention after January cure, so far without recurring.

Embodiment 3

Get Rhizoma Alpiniae Officinarum 30g, Rhizoma Cyperi 40g, Fructus Evodiae 10g, Pericarpium Citri Reticulatae 50g, Fructus Aurantii Immaturus 10g, Massa Medicata Fermentata 15g, Rhizoma Atractylodis Macrocephalae (parched) 40g, Fructus Citri Sarcodactylis 3g, Os Sepiae 40g, Radix Paeoniae Alba 30g, Fructus Amomi Rotundus 40g, Rhizoma Corydalis 30g, Rhizoma Coptidis 20g, after rinsing is clean, cold drying under 40-55 ℃ of condition, pulverize 100 mesh sieves, behind ultraviolet radiation sterilization, made capsule.

Du Xiaoqiao, the woman, 37 years old, patient stomachache, the pain gesture is urgent, irritated irritability, pantothenic acid is noisy, xerostomia, through multi-treatment, DeGrain, take medicine of the present invention after the one and a half months symptom substantially disappear, continue to take medicine and consolidate curative effect, so far without recurring.

Embodiment 4

Get Rhizoma Alpiniae Officinarum 40g, Rhizoma Cyperi 5g, Fructus Evodiae 20g, Pericarpium Citri Reticulatae 20g, Fructus Aurantii Immaturus 20g, Massa Medicata Fermentata 50g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Fructus Citri Sarcodactylis 25g, Os Sepiae 33g, Radix Paeoniae Alba 6g, Fructus Amomi Rotundus 30g, Rhizoma Corydalis 6g, Rhizoma Coptidis 18g, after rinsing is clean, cold drying under 40-55 ℃ of condition, pulverize 100 mesh sieves, behind ultraviolet radiation sterilization, made capsule.

Zhang Zhenyu, the man, 42 years old, pain during Stomach in Patients, localized pain and tenderness, pain has prickling sensation, postprandial pain very to take medicine of the present invention three months, and transference cure is so far without recurring.

Claims

1. a medicine for the treatment of stomachache is characterized in that, comprises each component of following weight portion:

Rhizoma Coptidis 3～20.

2. a kind of medicine for the treatment of stomachache according to claim 1 is characterized in that, comprises each component of following weight portion:

Rhizoma Alpiniae Officinarum 20 Rhizoma Cyperis 25 Fructus Evodiaes 30

The Radix Paeoniae Alba 15 Fructus Amomi Rotunduss 18 Rhizoma Corydalis 15

Rhizoma Coptidis 12.

3. claim 1 or 2 described a kind of preparation methoies for the treatment of the medicine of stomachache is characterized in that, during preparation, after above-mentioned weight portion rinsing totally, 100 mesh sieves were pulverized in cold drying under 40-55 ℃ of condition, made capsule behind ultraviolet radiation sterilization.