CN112190541A - Privacy care gel product - Google Patents
Privacy care gel product Download PDFInfo
- Publication number
- CN112190541A CN112190541A CN202011032368.8A CN202011032368A CN112190541A CN 112190541 A CN112190541 A CN 112190541A CN 202011032368 A CN202011032368 A CN 202011032368A CN 112190541 A CN112190541 A CN 112190541A
- Authority
- CN
- China
- Prior art keywords
- component
- parts
- water
- inflammatory
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/38—Silver; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Abstract
The invention discloses a private nursing gel product, and belongs to the field of skin care products. The anti-inflammatory and bacteriostatic composition disclosed by the invention comprises a mixture of hyaluronic acid, chlorhexidine and benzalkonium chloride, silver ions and is combined with auxiliary raw materials with anti-inflammatory effects, so that the anti-inflammatory and bacteriostatic composition prepared by the invention can effectively inhibit bacteria at female private parts, improve the comfort level of the private parts and keep dry and comfortable. The anti-inflammatory and bacteriostatic composition can be processed into female private bacteriostatic products and the like, and has no toxicity or side effect.
Description
Technical Field
The invention belongs to the field of skin care products, and relates to a private nursing gel product.
Background
With the economic development and the improvement of living standard, the living pressure of people is improved. Women are prone to various problems such as skin problems, endocrine disorders, and so forth, as well as vaginal blockage or infection. The ideal sterilizing product should have broad-spectrum vaginal antibacterial activity, good solubility and dispersibility, safety, no harm to human body and convenient use.
However, the existing sterilization products are various in types and cause certain damage to the thin skin of the female vagina. Some can cause irritation to the skin; some problems of poor permeability, accumulation in a dark and humid environment, skin eruption and the like. Therefore, it is a necessary problem to develop a private care product having a wide antimicrobial spectrum and high safety.
Disclosure of Invention
The invention aims to provide an anti-inflammatory and antibacterial composition.
The invention aims to provide a preparation method of an anti-inflammatory and antibacterial composition.
It is an object of the present invention to provide a intimate care product comprising an anti-inflammatory and anti-bacterial composition.
It is an object of the present invention to provide a intimate care gel product comprising an anti-inflammatory and anti-bacterial composition.
The technical scheme adopted by the invention is as follows:
the invention provides an anti-inflammatory and antibacterial composition which comprises hyaluronic acid, a mixture of chlorhexidine and benzalkonium chloride and silver ions.
According to an embodiment of the invention, the hyaluronic acid comprises components A, B and C, the component A comprises acrylic acid (ester)/C10-30 alkanol acrylate crosspolymer, skin conditioning agent;
the component B comprises a humectant and sodium hyaluronate;
the component C comprises a pH regulator and water.
According to an embodiment of the present invention, the mixture of chlorhexidine and benzalkonium chloride comprises D, E and F, the component D comprises acrylates/C10-30 alkanol acrylate crosspolymer, skin conditioning agents and preservatives, and water;
the component E comprises a humectant;
the component F comprises a pH regulator and water.
According to an embodiment of the present invention, the silver ions include components G, H and I,
the component G comprises acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, an antibacterial agent and water;
the component H comprises a humectant;
the component I comprises a pH regulator and water.
According to an embodiment of the invention, the skin conditioning agent comprises at least one of hyaluronic acid, a mixture of chlorhexidine acetate and benzalkonium chloride, silver ions.
According to an embodiment of the invention, the humectant comprises at least one of glycerin, acrylic/C10-30 alkanol acrylate crosspolymer.
According to an embodiment of the present invention, the pH adjusting agent comprises at least one of triethanolamine, acrylates/C10-30 alkanol acrylate crosspolymer.
According to an embodiment of the invention, the preservative comprises at least one of benzalkonium chloride, chlorhexidine acetate, silver ions.
According to an embodiment of the invention, the antimicrobial agent comprises at least one of silver oxide, benzalkonium chloride, chlorhexidine acetate.
According to an embodiment of the invention, the composition comprises the following ingredients in parts by weight: the hyaluronic acid component A comprises 90-95 parts of water, 0.5-1 part of acrylic acid (acrylate/C10-30 alkanol acrylate cross-linked polymer and 0.02-0.05 part of chlorhexidine acetate; the component B comprises 3-7 parts of glycerin and 0.1-0.5 part of sodium hyaluronate; the component C comprises 0.1-1 part of triethanolamine and 2-5 parts of water;
according to an embodiment of the present invention, the mixture of chlorhexidine and benzalkonium chloride comprises D, E and F, and the component D comprises 90-92 parts of water, 0.5-0.8 part of acrylic acid/C10-30 alkanol acrylate crosspolymer, 0.1-0.3 part of chlorhexidine acetate and 0.1-0.3 part of benzalkonium chloride; the component E comprises 4-7 parts of glycerol; the component F comprises 0.1-1 part of triethanolamine and 2-5 parts of water;
according to the embodiment of the invention, the silver ions comprise components G, H and I, and the component G comprises acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer 0.5-1 part, and silver oxide 0.3-0.7 part; the component H comprises 3-7 parts of glycerol; the component I comprises 0.1-1 part of triethanolamine and 2-5 parts of water.
The present invention provides a process for the preparation of a composition as defined in any preceding claim, comprising the steps of:
(1) respectively weighing the component A into a container, and then sequentially weighing and uniformly stirring B, C, D, E, F, G, H, I components for later use;
(2) b, C is poured into the phase A, and the mixture is stirred evenly;
(3) adding the rest D, E, F, G, H, I into the container, and stirring to obtain private gel product.
The present invention provides a intimate care product comprising an anti-inflammatory and anti-bacterial composition as defined in any preceding claim.
Hyaluronic acid has unique skin protecting effect, can keep skin moist and smooth, and is fine, tender, and elastic, and has effects of preventing wrinkle, removing wrinkle, caring skin, promoting health, and recovering skin physiological function.
Chlorhexidine has quite strong broad-spectrum antibacterial and bactericidal effects, is a better bactericidal and disinfectant drug, and has stronger antibacterial effects on gram positive and negative bacteria than benzalkonium bromide.
Benzalkonium chloride is a cationic surfactant, is a broad-spectrum bactericide, can change the permeability of bacterial cytoplasmic membranes, enables bacterial cytoplasmic substances to seep outwards, and blocks the metabolism of the bacterial cytoplasmic substances to play a role in killing. Has strong effect on gram-positive bacteria
Silver ions can strongly attract sulfhydryl (-SH) groups on proteases in bacterial bodies, and can be rapidly combined with the sulfhydryl (-SH) groups to inactivate the proteases, so that the bacteria die. When the bacteria are killed by Ag +, the Ag + is dissociated from the bacterial corpses and then contacts with other bacterial colonies, and the process is repeatedly carried out.
The invention has the beneficial effects that:
the anti-inflammatory and bacteriostatic composition disclosed by the invention comprises a mixture of hyaluronic acid, chlorhexidine and benzalkonium chloride, silver ions and is combined with auxiliary raw materials with anti-inflammatory effects, so that the anti-inflammatory and bacteriostatic composition prepared by the invention can effectively inhibit bacteria at female private parts, improve the comfort level of the private parts and keep dry and comfortable.
Detailed Description
The starting materials, reagents or apparatus used in the following examples are conventionally commercially available or can be obtained by a method known in the art, unless otherwise specified. Wherein the chlorhexidine acetate is purchased from Henan Wangli biological technology limited, and the product number is 56-95-1; hyaluronic acid was purchased from Huaxifuruida biomedical Co., Ltd under the product number 20042842; benzalkonium chloride is available from Guangzhou Henan Fine chemical Co., Ltd, with a product number of CZ0J 030-2110; silver oxide is available from Yishanghu International (Shanghai) Co., Ltd under the designation 05040218.
Example 1 preparation of privacy Care gel products
Hyaluronic acid private gel:
(1) weighing 90.5 parts of water and 0.75 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer into a container with a stirrer, and fully soaking;
(2) weighing 0.04 part of chlorhexidine acetate, 5 parts of glycerol and 0.2 part of sodium hyaluronate, and uniformly stirring;
(3) weighing 0.51 part of triethanolamine and 3 parts of water by using a proper container, and uniformly stirring for later use;
(4) and adding the uniformly mixed triethanolamine solution into the mixture, and fully and uniformly stirring to obtain the hyaluronic acid private gel.
Chlorhexidine + benzalkonium chloride private gel:
(1) weighing 90.5 parts of water and 0.75 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer into a container with a stirrer, and fully soaking;
(2) weighing 0.12 part of chlorhexidine acetate, 5 parts of glycerol and 0.1 part of benzalkonium chloride, and uniformly stirring;
(3) weighing 0.53 part of triethanolamine and 3 parts of water by using a proper container, and uniformly stirring for later use;
(4) and adding the uniformly mixed triethanolamine solution into the mixture, and fully and uniformly stirring to obtain the chlorhexidine + benzalkonium chloride private gel.
Silver ion privacy gel:
(1) weighing 90.22 parts of water and 0.75 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer into a container with a stirrer, and fully soaking;
(2) weighing 0.5 part of silver oxide and 5 parts of glycerin, and uniformly stirring;
(3) weighing 0.53 part of triethanolamine and 3 parts of water by using a proper container, and uniformly stirring for later use;
(4) and adding the uniformly mixed triethanolamine solution into the mixture, and fully and uniformly stirring to obtain the silver ion private gel.
The examples and comparative examples were prepared by the methods described in example 1, examples 2 to 4, and comparative examples 1 to 3, and the formulations are shown in tables 1 and 2.
The formulations of the different compositions of examples 1-4 are shown in Table 1:
TABLE 1
Formulations of the different compositions of comparative examples 1-3 are shown in table 2:
TABLE 2
The next effect test is carried out on the composition.
The test was carried out using an ATP fluorescence detector, Byes-420, from Banyi accurate measuring instrument (Shanghai) Co., Ltd. to test the bactericidal activity of each of the examples and comparative examples.
The test method comprises the following steps:
1. firstly, one end with a cotton head is infected with bacteria, and the number of the bacteria at the moment is tested and recorded as the initial number of the bacteria V1;
2. smearing a sample to be tested on a cotton head which is infected with bacteria, and testing the bacteria number V2 after shaking for 1 minute;
3. (V1-V2)/V1 ═ f (sterilization rate)
The test results are shown in table 3:
TABLE 3 hyaluronic acid gel Sterilization Rate test results
TABLE 4 Chlorhexidine + benzalkonium chloride gel Sterilization Rate test results
TABLE 5 silver ion gel Sterilization Rate test results
The properties of the different compositions are shown in tables 3, 4 and 5. As can be seen from the table, the compositions provided in the examples of the present invention have anti-inflammatory and bacteriostatic effects. Therefore, the composition can be processed into nursing products, such as female private nursing products, hand sanitizer and the like, and the composition has an obvious effect by matching active ingredients, so that the anti-inflammation and bacteriostasis effects on a target area are realized.
The embodiments of the present invention have been described in detail, but the present invention is not limited to the embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art. Furthermore, the embodiments of the present invention and the features of the embodiments may be combined with each other without conflict.
Claims (10)
1. An anti-inflammatory and antibacterial composition, characterized in that it comprises a mixture of hyaluronic acid, chlorhexidine and benzalkonium chloride, silver ions.
2. The anti-inflammatory and anti-bacterial composition of claim 1, wherein said hyaluronic acid comprises components A, B and C, said component a comprising acrylates/C10-30 alkanol acrylate crosspolymer, skin conditioning agent;
the component B comprises a humectant and sodium hyaluronate;
the component C comprises a pH regulator and water.
3. The anti-inflammatory and antibacterial composition of claim 1, wherein said mixture of chlorhexidine and benzalkonium chloride comprises D, E and F, said component D comprises acrylates/C10-30 alkanol acrylate crosspolymer, skin conditioning agents and preservatives, and water;
the component E comprises a humectant;
the component F comprises a pH regulator and water.
4. The anti-inflammatory and antibacterial composition of claim 1, wherein said silver ions comprise components G, H and I, said component G comprising acrylates/C10-30 alkanol acrylate crosspolymer, antibacterial agent and water;
the component H comprises a humectant;
the component I comprises a pH regulator and water.
5. The composition of claim 2 or 3, wherein the skin conditioning agent comprises at least one of hyaluronic acid, a mixture of chlorhexidine and benzalkonium chloride, silver ions.
6. The composition of any of claims 2-4, wherein the humectant comprises at least one of glycerin, acrylic/C10-30 alkanol acrylate crosspolymer.
7. The composition of any of claims 2-4, wherein the pH adjusting agent comprises at least one of triethanolamine, acrylates/C10-30 alkanol acrylate crosspolymer.
8. The composition of any one of claims 2-4, wherein the antimicrobial agent comprises at least one of silver oxide, chlorhexidine, and benzalkonium chloride.
9. The composition according to claim 1, characterized in that it comprises the following ingredients in parts by weight: the hyaluronic acid component A comprises 90-95 parts of water, 0.5-1 part of acrylic acid (acrylate/C10-30 alkanol acrylate cross-linked polymer and 0.02-0.05 part of chlorhexidine acetate; the component B comprises 3-7 parts of glycerin and 0.1-0.5 part of sodium hyaluronate; the component C comprises 0.1-1 part of triethanolamine and 2-5 parts of water;
the mixture of the chlorhexidine and the benzalkonium chloride comprises D, E and F, and the component D comprises 90 to 92 parts of water, 0.5 to 0.8 part of acrylic acid (ester)/C10 to 30 parts of alkanol acrylate cross-linked polymer, 0.1 to 0.3 part of chlorhexidine acetate and 0.1 to 0.3 part of benzalkonium chloride; the component E comprises 4-7 parts of glycerol; the component F comprises 0.1-1 part of triethanolamine and 2-5 parts of water;
the silver ions comprise components G, H and I, and the component G comprises 90-93 parts of water, 0.5-1 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer and 0.3-0.7 part of silver oxide; the component H comprises 3-7 parts of glycerol; the component I comprises 0.1-1 part of triethanolamine and 2-5 parts of water.
10. A intimate care product comprising the anti-inflammatory and anti-bacterial composition of any of claims 1 to 9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011032368.8A CN112190541A (en) | 2020-09-27 | 2020-09-27 | Privacy care gel product |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011032368.8A CN112190541A (en) | 2020-09-27 | 2020-09-27 | Privacy care gel product |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112190541A true CN112190541A (en) | 2021-01-08 |
Family
ID=74008474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011032368.8A Pending CN112190541A (en) | 2020-09-27 | 2020-09-27 | Privacy care gel product |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112190541A (en) |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005087270A1 (en) * | 2004-03-10 | 2005-09-22 | Edko Trading And Representation Co. Ltd. | Anti-vaginitis compositions comprising a triazole |
| US20100092577A1 (en) * | 2007-03-29 | 2010-04-15 | Pier Luigi Guasti | Topical compositions containing magaldrate |
| JP2010100596A (en) * | 2008-10-21 | 2010-05-06 | Araiansu:Kk | Composition for preventing drug-resistant bacteria infection and compounded with mastic and squalane |
| CN105055304A (en) * | 2015-08-04 | 2015-11-18 | 河北冀衡化学股份有限公司 | Leave-on skin care and disinfection gel containing composite sterilization component, and preparation method thereof |
| CN106074783A (en) * | 2016-08-05 | 2016-11-09 | 刘之伟 | A kind of silver ion bacteriostatic gel and preparation method thereof |
| CN106214882A (en) * | 2016-08-19 | 2016-12-14 | 吉安市御美丽健康产业股份有限公司 | A kind of high intensity antibacterial liquid gel and preparation method thereof |
| CN106309237A (en) * | 2016-09-26 | 2017-01-11 | 杭州惠博士生物科技有限公司 | Hyaluronic acid private part care gel and preparation method thereof |
| CN107375152A (en) * | 2017-09-07 | 2017-11-24 | 平舆玛雅生物工程有限公司 | A kind of cation sterilization gel and preparation method thereof and the aloetic bacteriostatic gel product comprising the cation sterilization gel |
-
2020
- 2020-09-27 CN CN202011032368.8A patent/CN112190541A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005087270A1 (en) * | 2004-03-10 | 2005-09-22 | Edko Trading And Representation Co. Ltd. | Anti-vaginitis compositions comprising a triazole |
| US20100092577A1 (en) * | 2007-03-29 | 2010-04-15 | Pier Luigi Guasti | Topical compositions containing magaldrate |
| JP2010100596A (en) * | 2008-10-21 | 2010-05-06 | Araiansu:Kk | Composition for preventing drug-resistant bacteria infection and compounded with mastic and squalane |
| CN105055304A (en) * | 2015-08-04 | 2015-11-18 | 河北冀衡化学股份有限公司 | Leave-on skin care and disinfection gel containing composite sterilization component, and preparation method thereof |
| CN106074783A (en) * | 2016-08-05 | 2016-11-09 | 刘之伟 | A kind of silver ion bacteriostatic gel and preparation method thereof |
| CN106214882A (en) * | 2016-08-19 | 2016-12-14 | 吉安市御美丽健康产业股份有限公司 | A kind of high intensity antibacterial liquid gel and preparation method thereof |
| CN106309237A (en) * | 2016-09-26 | 2017-01-11 | 杭州惠博士生物科技有限公司 | Hyaluronic acid private part care gel and preparation method thereof |
| CN107375152A (en) * | 2017-09-07 | 2017-11-24 | 平舆玛雅生物工程有限公司 | A kind of cation sterilization gel and preparation method thereof and the aloetic bacteriostatic gel product comprising the cation sterilization gel |
Non-Patent Citations (3)
| Title |
|---|
| 中华医学会编: "《第八次全国妇产科学学术会议论文汇编》", 30 November 2004 * |
| 姜怀等主编: "《汽车用纺织品的开发与应用》", 30 April 2009 * |
| 裘炳毅等: "《现代化妆品科学与技术》", 31 March 2016 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Hübner et al. | Octenidine dihydrochloride, a modern antiseptic for skin, mucous membranes and wounds | |
| US20060074029A1 (en) | Topical antimicrobial composition having improved moisturization properties | |
| CN111135160B (en) | Foam wash-free antibacterial liquid for personal protection and preparation method thereof | |
| CN108186403A (en) | A kind of impregnated wipe and preparation method thereof | |
| US20130274345A1 (en) | Antimicrobial Composition Having Skincare Properties | |
| CN107961399A (en) | A kind of water-based body lotion containing complex antimicrobials | |
| CN111467249A (en) | Washing-free antibacterial gel and preparation method thereof | |
| EP2320915B1 (en) | Gentle, non-irritating, non-alcohoholic skin disinfectant | |
| CN112891372B (en) | Hydrogen peroxide and nano-silver compound hand disinfectant and preparation method thereof | |
| WO2008061375A1 (en) | Antiseptic | |
| US8173147B2 (en) | Gentle, non-irritating, non-alcoholic skin disinfectant | |
| CN112190541A (en) | Privacy care gel product | |
| EP2632432B1 (en) | Composition and method for treating wounds | |
| JP3577113B2 (en) | External preparation for skin | |
| EP0347225B1 (en) | Pharmaceutical compositions containing primycin | |
| CN112972281A (en) | Disinfectant-grade hand sanitizer containing salicylic acid microcapsules and preparation method thereof | |
| CN112057401A (en) | Hand-washing-free composite alcohol disinfectant and preparation method thereof | |
| CN112545917A (en) | Disinfecting gel and preparation method thereof | |
| EP3106172B1 (en) | Antimicrobial agents and their use | |
| CN108498399B (en) | Compound plant extract with antiseptic effect and application thereof in cosmetic antiseptic | |
| CN112236163A (en) | Enhancement of depsipeptide antibiotic antibacterial action using synergistic amounts of boric acid | |
| JP2004269410A (en) | Alcohol sterilization preparation | |
| CN116271199A (en) | Liquid adhesive bandage and preparation method thereof | |
| RU2246953C1 (en) | Disinfecting agent | |
| CN116603007A (en) | Wound surface disinfection spray and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |