CN112136998A - Formula and preparation method of solid beverage for assisting in reducing blood fat and improving blood circulation - Google Patents
Formula and preparation method of solid beverage for assisting in reducing blood fat and improving blood circulation Download PDFInfo
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- CN112136998A CN112136998A CN202010911580.5A CN202010911580A CN112136998A CN 112136998 A CN112136998 A CN 112136998A CN 202010911580 A CN202010911580 A CN 202010911580A CN 112136998 A CN112136998 A CN 112136998A
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Abstract
The invention discloses a solid beverage formula for assisting in reducing blood fat and improving blood circulation and a preparation method thereof, wherein the formula comprises the following raw materials in parts by mass: 13-17 parts of sophora flower, 8-12 parts of eucommia ulmoides leaves, 3-7 parts of fried cassia seeds, 3-7 parts of rhizoma polygonati, 3-7 parts of coix seeds, 4-6 parts of angelica sinensis, 3-7 parts of turmeric, 3-8 parts of safflower, 4-6 parts of stevia rebaudiana, 18-22 parts of fuding white tea and 17-23 parts of hawthorn; the ministerial drugs are folium Eucommiae, rhizoma Polygonati, and radix Angelicae sinensis, and have effects of invigorating qi, promoting blood circulation, and invigorating kidney; the adjuvant drugs are semen Cassiae, Coicis semen, and Curcuma rhizome, which are selected for removing liver heat, invigorating spleen, promoting blood circulation and removing blood stasis; the guiding drug is safflower which is used for activating blood and guiding the drug into heart channels; stevia rebaudiana, white tea and hawthorn are used as auxiliary medicines and play a role in seasoning, and the curative effect is obvious through the combination of the raw materials.
Description
Technical Field
The invention relates to the field of traditional Chinese medicine formulas, in particular to a solid beverage formula for assisting in reducing blood fat and improving blood circulation and a preparation method thereof.
Background
With the improvement of living standard of people, the prevalence rate of cardiovascular and cerebrovascular diseases is on the trend of increasing year by year. Blood vessels are the conduit for the circulation of blood throughout the body and provide sufficient nutrient and oxygen support for the various organs of the body. Therefore, the health of blood vessels also becomes a current index for measuring the health of a person. The blood vessels are aged gradually as people age, which is why the probability of cardiovascular disease in the elderly is significantly higher than in the average population. However, the age of onset has been advancing toward younger age in recent years, and early atherosclerotic lesions have also been found in autopsy of some young adults and even children. It has been shown that the disease is caused by various factors acting on different links, which are called risk factors, mainly including hyperlipidemia, hypertension and diabetes. Hyperlipemia is one of the susceptibility factors of cardiovascular and cerebrovascular diseases such as coronary heart disease, cerebral arteriosclerosis, cerebrovascular accident and the like, and prevention and treatment measures are taken to reduce the blood fat level, so that the development of atherosclerotic lesions can be delayed, regression can be promoted, and the morbidity and mortality of coronary heart disease, cerebral arteriosclerosis and the like can be reduced.
Hyperlipemia belongs to the category of turbid phlegm disease in Chinese traditional medicine, and Chinese medicine holds that the body is invaded by internal factors or external factors, so that pathological substances such as phlegm, dampness, turbidity, stasis and the like are generated in the body, or the pathological substances flow away from blood vessels or are accumulated in internal organs, and the veins are blocked after a long time. This theory is basically similar to the pathological course of modern medical hyperlipidemia. The instant solid beverage is prepared by combining traditional Chinese medicinal materials with the pharmacological functions of clearing heat and removing toxicity, activating blood and removing stasis, clearing and resolving phlegm turbidity and the like, tea leaves and dried fruits, and accords with the theory of traditional Chinese medicine that phlegm is caused by body fluid and is formed by blood stasis and the homology of body fluid and blood. Phlegm-stasis usually occurs together and is a disease, so it is the principle of treating phlegm and blood stasis. Furthermore, the occurrence and development of the disease are considered to have close relationship with diet, and the diet therapy is a basic therapy and is an important means for preventing diseases.
Therefore, designing a solid beverage formula for assisting in reducing blood fat and improving blood circulation according to the combination of the traditional Chinese medicine theory and the modern medical theory is a problem to be solved urgently by technical personnel in the related field.
Disclosure of Invention
In order to solve the technical problems, the technical scheme provided by the invention is as follows: the formula of the solid beverage for assisting in reducing blood fat and improving blood circulation comprises the following raw materials in parts by mass: 13-17 parts of sophora flower, 8-12 parts of eucommia ulmoides leaves, 3-7 parts of fried cassia seeds, 3-7 parts of rhizoma polygonati, 3-7 parts of coix seeds, 4-6 parts of angelica sinensis, 3-7 parts of turmeric, 3-8 parts of safflower, 4-6 parts of stevia rebaudiana, 18-22 parts of fuding white tea and 17-23 parts of hawthorn.
Preferably, the feed consists of the following raw materials in parts by mass: 15 parts of sophora flower, 10 parts of eucommia leaf, 5 parts of fried cassia seed, 5 parts of rhizoma polygonati, 5 parts of semen coicis, 5 parts of angelica, 5 parts of turmeric, 5 parts of safflower, 5 parts of stevia rebaudiana, 20 parts of fuding white tea and 20 parts of hawthorn.
Preferably, the preparation method comprises the following steps:
(1) selecting raw materials according to a formula, uniformly mixing the raw materials and soaking the raw materials in pure water;
(2) breaking the walls of the raw materials soaked in the step (1) by using ultrasonic cell wall breaking equipment;
(3) extracting the mixed medicinal materials subjected to the wall breaking treatment in the step (2) by using vacuum low-temperature extraction equipment;
(4) and (4) drying the mixed medicinal materials subjected to the vacuum low-temperature treatment in the step (3) by using particle spray drying equipment, and finally subpackaging and warehousing.
In the invention:
1. sophora flower is bitter and slightly cold; it enters liver and large intestine meridians; cool blood to stop bleeding, clear liver heat to purge fire and remove dampness. Can be used for treating hematochezia, hemorrhoidal bleeding, bloody dysentery, metrorrhagia, hematemesis, epistaxis, liver heat with conjunctival congestion, headache, and vertigo;
the pharmacological action is as follows: has the effect of temporarily and obviously reducing blood pressure. Has effects of preventing and treating experimental arteriosclerosis, and is a natural green medicine for treating ischemic heart disease, angina pectoris, chronic cardiac insufficiency, hyperlipidemia, and preventing arteriosclerosis, myocardial infarction, cerebral thrombosis, etc.
2. Folium Eucommiae is slightly pungent and warm; entering liver and kidney meridians; tonify liver and kidney, strengthen tendons and bones. Can be used for treating deficiency of liver and kidney, dizziness, soreness of waist and knees, and flaccidity of tendons and bones;
the pharmacological action is as follows: (1) effect on cardiovascular system: eucommia ulmoides leaves were identified as inhibitors of angiotensin and cAMP; (2) effects on the immune system: chlorogenic acid, polyphenols, flavonoids, etc. in folium Eucommiae have effects of resisting tumor, increasing leukocyte, and enhancing immunity; (3) other functions are as follows: the folium Eucommiae also has antitumor and antioxidant effects.
3. Rhizoma Polygonati is sweet and neutral; spleen, lung and kidney meridians entered; invigorating qi and nourishing yin, invigorating spleen, moistening lung, and invigorating kidney, and can be used for treating deficiency of spleen and stomach qi, asthenia, stomach yin deficiency, xerostomia, anorexia, lung deficiency, dry cough, fatigue cough, hemoptysis, essence and blood deficiency, soreness of waist and knees, premature gray hair, internal heat, and diabetes;
the pharmacological action is as follows: (1) regulating blood sugar and reducing blood lipid; (2) can improve nonspecific immunity function; (3) the antibacterial, anti-inflammatory and antiviral agent has certain inhibiting effects on staphylococcus aureus, paratyphoid bacillus, escherichia coli, staphylococcus albus, actinomycetes and unicellular fungus saccharomyces cerevisiae; (4) the function of delaying senility: promoting synthesis of skin collagen fiber, and delaying skin aging; (5) improve the memory function.
4. Parched semen Cassiae is sweet, bitter and mature, and is slightly cold; it enters liver and large intestine meridians; clear heat, improve eyesight, moisten intestines and relax bowels. Can be used for treating conjunctival congestion, photophobia, lacrimation, headache, vertigo, dim eyesight, and constipation;
the pharmacological action is as follows: (1) the function of reducing blood pressure: the systolic pressure and the diastolic pressure can be obviously reduced, and the heart rate and the respiration are not obviously influenced; (2) blood fat reducing effect: has effects in reducing total cholesterol and triglyceride in blood plasma, and inhibiting platelet aggregation.
5. The coix seeds are sweet, light and cool; spleen, stomach and lung meridians entered; promoting diuresis and eliminating dampness, strengthening the spleen and relieving diarrhea, removing arthralgia, expelling pus, removing toxic substances and resolving masses for edema, beriberi, dysuresia, spleen deficiency and diarrhea, damp arthralgia and contracture, lung pain, intestinal abscess, excrescence wart and cancer;
the pharmacological action is as follows: has important regulation and control functions on blood sugar and blood fat.
6. Dang Gui is sweet, pungent and warm. It enters liver, heart and spleen meridians; tonify blood, activate blood, regulate menstruation, alleviate pain, moisten intestines to relieve constipation. Can be used for treating blood deficiency, sallow complexion, giddiness, palpitation, menoxenia, amenorrhea, dysmenorrhea, asthenia cold, abdominal pain, rheumatalgia, traumatic injury, superficial infection, pyocutaneous disease, intestinal dryness, and constipation. The wine angelica is capable of activating blood and stimulating menstrual flow; can be used for treating amenorrhea, dysmenorrhea, rheumatalgia, and traumatic injury.
The pharmacological action is as follows: (1) antiarrhythmic effect; (2) the function of expanding blood vessels; (3) inhibiting platelet aggregation.
7. Turmeric is pungent, bitter and warm. Spleen and liver meridian entered; break blood and move qi, dredge meridians to alleviate pain. Can be used for treating chest and hypochondrium stabbing pain, thoracic obstruction, cardialgia, dysmenorrhea, amenorrhea, abdominal mass, rheumatism, shoulder and arm pain, and traumatic injury with swelling and pain;
the pharmacological action is as follows: has effects of reducing serum cholesterol and beta-lipoprotein for hyperlipidemia.
8. Saffron is sweet and mild; heart and liver meridian entered; promoting blood circulation, removing blood stasis, cooling blood, removing toxic substance, resolving stagnation, and tranquilizing mind. Can be used for treating amenorrhea, abdominal mass, puerperal blood stasis, toxic heat, speckle, melancholy, stuffiness, palpitation, and mania;
the pharmacological action is as follows: enhancing coronary blood flow, and inhibiting thrombosis; has anticoagulant effect, and can inhibit platelet aggregation induced by adenosine diphosphate and collagen, and promote blood circulation.
9. Stevia rebaudiana is sweet in taste and mild in nature; entering lung and stomach meridians; has effects in promoting salivation, quenching thirst, and lowering blood pressure; can be used for treating diabetes and hypertension;
the pharmacological action is as follows: has vasodilating effect, and can be used as calcium antagonist.
10. The Fuding white tea has the effects of relieving alcoholism and sobering up, clearing heat and moistening lung, calming liver and benefiting blood, diminishing inflammation and detoxifying, reducing blood pressure and fat, eliminating fatigue and the like
11. The hawthorn is sour and sweet in taste and slightly warm in nature; spleen, stomach and liver meridians entered; has effects in promoting digestion, removing food stagnation, promoting qi circulation, and dispelling blood stasis; it can be used for treating food stagnation, dysentery, abdominal pain, hernia pain, chest pain due to blood stasis, and dysmenorrhea.
The pharmacological action is as follows: the contained fatty acid can promote fat digestion, reduce blood fat and resist atherosclerosis, and the hawthorn is frequently used singly to treat hyperlipidemia, coronary heart disease, hypertension and the like.
The invention has the following advantages: the invention combines the traditional Chinese medicine theory and the modern medical theory, adopts the raw material formula with homology of medicine and food, and is prepared into the instant solid beverage by the modern scientific extraction and processing technology, wherein the monarch drug is sophora flower, and the sophora flower is used for removing dampness and turbid urine, and the dampness of the disease is the first of the symptoms; the ministerial drugs are folium Eucommiae, rhizoma Polygonati, and radix Angelicae sinensis, and have effects of invigorating qi, promoting blood circulation, and invigorating kidney; the adjuvant drugs are semen Cassiae, Coicis semen, and Curcuma rhizome, which are selected for removing liver heat, invigorating spleen, promoting blood circulation and removing blood stasis; the guiding drug is safflower which is used for activating blood and guiding the drug into heart channels; stevia rebaudiana, white tea and hawthorn are used as auxiliary medicines and play a role in seasoning, and the combination of the raw materials has obvious curative effect and no side effect.
Detailed Description
Example one
The formula of the solid beverage for assisting in reducing blood fat and improving blood circulation comprises the following raw materials in parts by mass: 13 parts of sophora flower, 8 parts of eucommia leaf, 3 parts of fried cassia seed, 3 parts of rhizoma polygonati, 3 parts of semen coicis, 4 parts of angelica, 3 parts of turmeric, 3 parts of safflower, 4 parts of stevia rebaudiana, 18 parts of fuding white tea and 17 parts of hawthorn.
The preparation method comprises the following steps:
(1) selecting raw materials according to a formula, uniformly mixing the raw materials and soaking the raw materials in pure water;
(2) breaking the walls of the raw materials soaked in the step (1) by using ultrasonic cell wall breaking equipment;
(3) extracting the mixed medicinal materials subjected to the wall breaking treatment in the step (2) by using vacuum low-temperature extraction equipment;
(4) and (4) drying the mixed medicinal materials subjected to the vacuum low-temperature treatment in the step (3) by using particle spray drying equipment, and finally subpackaging and warehousing.
Example two
The formula of the solid beverage for assisting in reducing blood fat and improving blood circulation is characterized by comprising the following raw materials in parts by mass: 17 parts of sophora flower, 12 parts of eucommia leaves, 7 parts of fried cassia seeds, 7 parts of sealwort, 7 parts of coix seeds, 6 parts of angelica, 7 parts of turmeric, 8 parts of safflower, 6 parts of stevia rebaudiana, 22 parts of fuding white tea and 23 parts of hawthorn.
The preparation method comprises the following steps:
(1) selecting raw materials according to a formula, uniformly mixing the raw materials and soaking the raw materials in pure water;
(2) breaking the walls of the raw materials soaked in the step (1) by using ultrasonic cell wall breaking equipment;
(3) extracting the mixed medicinal materials subjected to the wall breaking treatment in the step (2) by using vacuum low-temperature extraction equipment;
(4) and (4) drying the mixed medicinal materials subjected to the vacuum low-temperature treatment in the step (3) by using particle spray drying equipment, and finally subpackaging and warehousing.
EXAMPLE III
The formula of the solid beverage for assisting in reducing blood fat and improving blood circulation comprises the following raw materials in parts by mass: 15 parts of sophora flower, 10 parts of eucommia leaf, 5 parts of fried cassia seed, 5 parts of rhizoma polygonati, 5 parts of semen coicis, 5 parts of angelica, 5 parts of turmeric, 5 parts of safflower, 5 parts of stevia rebaudiana, 20 parts of fuding white tea and 20 parts of hawthorn.
The preparation method comprises the following steps:
(1) selecting raw materials according to a formula, uniformly mixing the raw materials and soaking the raw materials in pure water;
(2) breaking the walls of the raw materials soaked in the step (1) by using ultrasonic cell wall breaking equipment;
(3) extracting the mixed medicinal materials subjected to the wall breaking treatment in the step (2) by using vacuum low-temperature extraction equipment;
(4) and (4) drying the mixed medicinal materials subjected to the vacuum low-temperature treatment in the step (3) by using particle spray drying equipment, and finally subpackaging and warehousing.
Firstly, formula sensory test:
compared with the formula 1, the formula adopts the following raw materials in parts by mass: 15 parts of sophora flower, 10 parts of pseudo-ginseng flower, 5 parts of chrysanthemum, 10 parts of cassia seed, 5 parts of safflower, 5 parts of rose, 5 parts of apocynum venetum, 5 parts of turmeric and 40 parts of green tea.
Compared with the formula 2, the formula adopts the following raw materials in parts by mass: 15 parts of sophora flower, 10 parts of pseudo-ginseng flower, 10 parts of fried cassia seed, 5 parts of safflower, 5 parts of rose, 5 parts of gynostemma pentaphylla, 5 parts of stevia rebaudiana, 5 parts of turmeric and 35 parts of green tea.
The experimental formula adopts the following raw materials in parts by mass: 15 parts of sophora flower, 10 parts of eucommia leaf, 5 parts of fried cassia seed, 5 parts of rhizoma polygonati, 5 parts of semen coicis, 5 parts of angelica, 5 parts of safflower, 5 parts of turmeric, 5 parts of stevia rebaudiana, 20 parts of fuding white tea and 20 parts of hawthorn.
The No. 1 formula is found to be too strong in medicine taste through screening and is not suitable for being drunk as a common food; no. 2 formula can be color and taste, but the medicines prohibited by common foods can be added, and only abandon; therefore, the formula No. 3 is determined to be adopted.
II, an efficacy animal experiment (implemented by Chinese disease prevention and control center nutrition and food safety):
50 rats are randomly divided into two groups, and the groups are divided into 25 rats; one group is an experimental group, the medicinal tea is drunk, the other group is a control group, and after 30-day feeding experiments, the results are as follows: the medicinal tea has no obvious influence on the weight of a rat; the concentration of serum total cholesterol is obviously reduced; serum triglyceride concentration decreased significantly: serum high density lipoprotein cholesterol concentration had no significant effect. It is judged to have blood lipid regulating effect.
Thirdly, a crowd effect observation experiment (implemented by an Angel epidemic prevention station):
80 volunteers were randomly divided into two groups of 40 persons each, and blood was drawn before the experiment as the control base; one group of the medicinal tea is the experimental group and the other group of the medicinal tea is the control group and the common tea is drunk, and through 15-day blood drawing detection comparison, the serum cholesterol and the serum triglyceride in the experimental group are remarkably reduced, and the statistical analysis shows that the medicinal tea has the effects of reducing the serum cholesterol and the serum triglyceride:
1. comparison of the change in blood lipid levels before and after taking two groups of teas:
compared with serum TC and TG, the TC and TG of the serum are obviously reduced before and after the experimental group tea taking; (TC: t 3.01P <0.01 TG: t 5.57P <0.01), with very significant differences;
compared with the control group before and after taking the tea, the serum TC and TG have no obvious reduction; (TC: t ═ 0.972P <0.05 TG: t ═ 1.34P < 0.05);
the comparison between the two groups of sample average value groups has obvious difference; (TC: t-2.972P <0.01 TG: t-2.086P < 0.05).
2. Changes in blood lipid levels of hyperlipidemic persons and healthy persons before and after tea administration in experimental groups:
after the hyperlipemia patient takes the tea, the serum TG is obviously reduced (t is 4.983P <0.01), and the difference is very obvious;
there was no significant difference in TC by statistical treatment (t 2.007P < 0.05);
the serum TC and TG also show obvious reduction after healthy people take the tea, (TC: t ═ 2.257P <0.05 TG: t ═ 4.14P <0.01) has obvious difference.
3. Evaluation and analysis of the blood fat reducing effect show that:
the total effective rate of reducing TC is 68% (wherein: significant 14/40, effective 13/40; X2-7.218P < 0.01);
93 percent of total effective rate for reducing TG (wherein, the effective rate is 16/40, 21/40, x2=37.602P<0.01)。
The present invention and the embodiments thereof have been described above without limitation, and it is within the scope of the present invention that those skilled in the art should be able to devise similar structural modes and embodiments without inventive changes without departing from the spirit and scope of the present invention.
Claims (3)
1. The formula of the solid beverage for assisting in reducing blood fat and improving blood circulation is characterized by comprising the following raw materials in parts by mass: 13-17 parts of sophora flower, 8-12 parts of eucommia ulmoides leaves, 3-7 parts of fried cassia seeds, 3-7 parts of rhizoma polygonati, 3-7 parts of coix seeds, 4-6 parts of angelica sinensis, 3-7 parts of turmeric, 3-8 parts of safflower, 4-6 parts of stevia rebaudiana, 18-22 parts of fuding white tea and 17-23 parts of hawthorn.
2. The solid beverage formula for assisting in reducing blood fat and improving blood circulation according to claim 1, which is characterized by comprising the following raw materials in parts by mass: 15 parts of sophora flower, 10 parts of eucommia leaf, 5 parts of fried cassia seed, 5 parts of rhizoma polygonati, 5 parts of semen coicis, 5 parts of angelica, 5 parts of turmeric, 5 parts of safflower, 5 parts of stevia rebaudiana, 20 parts of fuding white tea and 20 parts of hawthorn.
3. The formula of the solid beverage for assisting in reducing blood fat and improving blood circulation according to claim 1, wherein the preparation method comprises the following steps:
(1) selecting raw materials according to a formula, uniformly mixing the raw materials and soaking the raw materials in pure water;
(2) breaking the walls of the raw materials soaked in the step (1) by using ultrasonic cell wall breaking equipment;
(3) extracting the mixed medicinal materials subjected to the wall breaking treatment in the step (2) by using vacuum low-temperature extraction equipment;
(4) and (4) drying the mixed medicinal materials subjected to the vacuum low-temperature treatment in the step (3) by using particle spray drying equipment, and finally subpackaging and warehousing.
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CN114947032A (en) * | 2022-05-17 | 2022-08-30 | 岳小鸥 | A solid beverage for improving blood quality and promoting nutrition balance |
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CN107372979A (en) * | 2017-09-20 | 2017-11-24 | 贵阳健圣堂药材有限公司 | A kind of health protection tea that can help relaxing bowels to lose weight, prevention high fat of blood and fatty liver and preparation method thereof |
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CN114042126A (en) * | 2022-01-07 | 2022-02-15 | 江西中医药大学 | Traditional Chinese medicine composition for ascending clear, eliminating turbid, promoting diuresis, benefiting qi, losing weight and reducing fat and preparation method thereof |
CN114042126B (en) * | 2022-01-07 | 2022-03-18 | 江西中医药大学 | Traditional Chinese medicine composition for ascending clear, eliminating turbid, promoting diuresis, benefiting qi, losing weight and reducing fat and preparation method thereof |
CN114947032A (en) * | 2022-05-17 | 2022-08-30 | 岳小鸥 | A solid beverage for improving blood quality and promoting nutrition balance |
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