CN112107558A - 药物组合物、制备及其用途 - Google Patents

药物组合物、制备及其用途 Download PDF

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Publication number
CN112107558A
CN112107558A CN202010861645.XA CN202010861645A CN112107558A CN 112107558 A CN112107558 A CN 112107558A CN 202010861645 A CN202010861645 A CN 202010861645A CN 112107558 A CN112107558 A CN 112107558A
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CN
China
Prior art keywords
compound
target
nanoparticles
nanoparticle
pharmaceutical
Prior art date
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Pending
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CN202010861645.XA
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English (en)
Chinese (zh)
Inventor
阿格尼丝·波迪艾尔
劳伦特·莱维
马里-艾迪斯·梅尔
奥德蕾·达尔蒙
马蒂厄·热尔曼
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Nanobiotix SA
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Kuradigam
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Publication of CN112107558A publication Critical patent/CN112107558A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5115—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN202010861645.XA 2013-05-30 2014-05-30 药物组合物、制备及其用途 Pending CN112107558A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361828794P 2013-05-30 2013-05-30
US61/828,794 2013-05-30
EP13305712.5 2013-05-30
EP13305712 2013-05-30
CN201480031188.4A CN105407878A (zh) 2013-05-30 2014-05-30 药物组合物、制备及其用途

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201480031188.4A Division CN105407878A (zh) 2013-05-30 2014-05-30 药物组合物、制备及其用途

Publications (1)

Publication Number Publication Date
CN112107558A true CN112107558A (zh) 2020-12-22

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CN202010861645.XA Pending CN112107558A (zh) 2013-05-30 2014-05-30 药物组合物、制备及其用途
CN201480031188.4A Pending CN105407878A (zh) 2013-05-30 2014-05-30 药物组合物、制备及其用途

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Country Status (17)

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US (2) US10413509B2 (enExample)
EP (1) EP3003288A1 (enExample)
JP (1) JP6387400B2 (enExample)
KR (1) KR102245421B1 (enExample)
CN (2) CN112107558A (enExample)
AU (1) AU2014273043B2 (enExample)
BR (1) BR112015029853A2 (enExample)
CA (1) CA2913023C (enExample)
EA (1) EA038671B1 (enExample)
HK (1) HK1222563A1 (enExample)
MA (1) MA38687A1 (enExample)
MX (1) MX376269B (enExample)
NZ (1) NZ714273A (enExample)
SG (1) SG11201509436TA (enExample)
UA (1) UA116380C2 (enExample)
WO (1) WO2014191569A1 (enExample)
ZA (1) ZA201509307B (enExample)

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KR102025743B1 (ko) 2011-12-16 2019-09-26 나노비오?스 금속성 및 산화하프늄 소재를 포함하는 나노입자, 이의 제조 및 용도
UA116380C2 (uk) 2013-05-30 2018-03-12 Нанобіотікс Посилення терапевтичної або профілактичної ефективності фармацевтичної сполуки
FI3229776T3 (fi) 2014-11-25 2023-08-15 Curadigm Sas Farmaseuttinen koostumus, joka yhdistää ainakin kaksi erillistä nanopartikkelia ja farmaseuttisen yhdisteen, sen valmistus ja käytöt
DK3236934T3 (da) * 2014-11-25 2024-08-19 Curadigm Sas Farmaceutisk sammensætning, fremstilling og anvendelser deraf
ES2890662T3 (es) 2014-11-25 2022-01-21 Curadigm Sas Composiciones farmacéuticas, preparación y usos de las mismas
US20170258937A1 (en) 2014-11-25 2017-09-14 Nanobiotix Pharmaceutical composition, preparation and uses thereof
EP3258917B1 (en) * 2015-02-19 2022-12-21 Carnegie Mellon University Methods to reduce toxicities and to improve bioavailabilities of nanodrugs
HK1246160A1 (zh) 2015-05-28 2018-09-07 Nanobiotix 用作治疗性疫苗的纳米粒子
CN105055447B (zh) * 2015-06-23 2018-03-13 中南大学湘雅二医院 氧化铁纳米颗粒用于制备改善厄洛替尼耐药性药物的应用
WO2020006493A1 (en) * 2018-06-29 2020-01-02 North Carolina State University In situ sprayed bioresponsive immunotherapeutic gel for post-surgical treatment
CN108969757B (zh) * 2018-07-11 2021-07-27 浙江大学 负载microRNA的氧化铈纳米复合水凝胶及制备方法和应用
CN110498607B (zh) * 2019-08-21 2022-03-08 中国科学院上海硅酸盐研究所 一种多功能钙硅基稀土掺杂的生物活性粉体及其制备方法和应用

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CN102470173A (zh) * 2009-07-10 2012-05-23 纳米生物技术公司 金属纳米粒子、其制备和应用
US20120237566A1 (en) * 2011-03-15 2012-09-20 Venture Isles, LLC Inhibiting stomach-acid release, reducing inflammation and preventing and treating cancer: compositions and methods of use

Also Published As

Publication number Publication date
EP3003288A1 (en) 2016-04-13
EA038671B1 (ru) 2021-10-01
AU2014273043A1 (en) 2015-12-03
JP6387400B2 (ja) 2018-09-05
KR102245421B1 (ko) 2021-04-29
ZA201509307B (en) 2017-04-26
NZ714273A (en) 2019-04-26
HK1222563A1 (zh) 2017-07-07
US20160184225A1 (en) 2016-06-30
AU2014273043B2 (en) 2019-02-07
CA2913023A1 (en) 2014-12-04
SG11201509436TA (en) 2015-12-30
WO2014191569A1 (en) 2014-12-04
US20200009050A1 (en) 2020-01-09
MX2015016456A (es) 2016-03-03
JP2016522833A (ja) 2016-08-04
KR20160013212A (ko) 2016-02-03
CA2913023C (en) 2021-06-08
US11357724B2 (en) 2022-06-14
UA116380C2 (uk) 2018-03-12
BR112015029853A2 (pt) 2017-07-25
MX376269B (es) 2025-03-07
US10413509B2 (en) 2019-09-17
CN105407878A (zh) 2016-03-16
MA38687A1 (fr) 2017-12-29
EA201592279A1 (ru) 2016-06-30

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