EA038671B1 - Способ повышения терапевтической или профилактической эффективности представляющего интерес фармацевтического соединения - Google Patents

Способ повышения терапевтической или профилактической эффективности представляющего интерес фармацевтического соединения Download PDF

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Publication number
EA038671B1
EA038671B1 EA201592279A EA201592279A EA038671B1 EA 038671 B1 EA038671 B1 EA 038671B1 EA 201592279 A EA201592279 A EA 201592279A EA 201592279 A EA201592279 A EA 201592279A EA 038671 B1 EA038671 B1 EA 038671B1
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EA
Eurasian Patent Office
Prior art keywords
compound
nanoparticle
interest
subject
biocompatible
Prior art date
Application number
EA201592279A
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English (en)
Russian (ru)
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EA201592279A1 (ru
Inventor
Аньес Поттье
Лоран Леви
Мари-Эдит Мейер
Одри Дармон
Маттье Жермэн
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Кюрадигм Сас
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Application filed by Кюрадигм Сас filed Critical Кюрадигм Сас
Publication of EA201592279A1 publication Critical patent/EA201592279A1/ru
Publication of EA038671B1 publication Critical patent/EA038671B1/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5115Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/70Nanostructure
    • Y10S977/773Nanoparticle, i.e. structure having three dimensions of 100 nm or less

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EA201592279A 2013-05-30 2014-05-30 Способ повышения терапевтической или профилактической эффективности представляющего интерес фармацевтического соединения EA038671B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361828794P 2013-05-30 2013-05-30
EP13305712 2013-05-30
PCT/EP2014/061296 WO2014191569A1 (en) 2013-05-30 2014-05-30 Pharmaceutical composition, preparation and uses thereof

Publications (2)

Publication Number Publication Date
EA201592279A1 EA201592279A1 (ru) 2016-06-30
EA038671B1 true EA038671B1 (ru) 2021-10-01

Family

ID=48656009

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201592279A EA038671B1 (ru) 2013-05-30 2014-05-30 Способ повышения терапевтической или профилактической эффективности представляющего интерес фармацевтического соединения

Country Status (17)

Country Link
US (2) US10413509B2 (enExample)
EP (1) EP3003288A1 (enExample)
JP (1) JP6387400B2 (enExample)
KR (1) KR102245421B1 (enExample)
CN (2) CN112107558A (enExample)
AU (1) AU2014273043B2 (enExample)
BR (1) BR112015029853A2 (enExample)
CA (1) CA2913023C (enExample)
EA (1) EA038671B1 (enExample)
HK (1) HK1222563A1 (enExample)
MA (1) MA38687A1 (enExample)
MX (1) MX376269B (enExample)
NZ (1) NZ714273A (enExample)
SG (1) SG11201509436TA (enExample)
UA (1) UA116380C2 (enExample)
WO (1) WO2014191569A1 (enExample)
ZA (1) ZA201509307B (enExample)

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UA116380C2 (uk) 2013-05-30 2018-03-12 Нанобіотікс Посилення терапевтичної або профілактичної ефективності фармацевтичної сполуки
WO2016083331A1 (en) * 2014-11-25 2016-06-02 Nanobiotix Pharmaceutical composition, preparation and uses thereof
JP6836510B2 (ja) * 2014-11-25 2021-03-03 キュラディグム・エスアエスCuradigm Sas 少なくとも2つの異なるナノ粒子と医薬化合物とを組み合わせた医薬組成物、その調製及び使用
HUE056175T2 (hu) 2014-11-25 2022-01-28 Curadigm Sas Gyógyászati készítmények, elõállításuk és alkalmazásaik
TW201628656A (zh) 2014-11-25 2016-08-16 奈諾生技公司 醫藥組合物、其製備與用途
US10792366B2 (en) * 2015-02-19 2020-10-06 Carnegie Mellon University Methods to reduce toxicities and to improve bioavailabilities of nanodrugs
US11096962B2 (en) 2015-05-28 2021-08-24 Nanobiotix Nanoparticles for use as a therapeutic vaccine
CN105055447B (zh) * 2015-06-23 2018-03-13 中南大学湘雅二医院 氧化铁纳米颗粒用于制备改善厄洛替尼耐药性药物的应用
JP7579570B2 (ja) * 2018-06-29 2024-11-08 ノース・キャロライナ・ステイト・ユニヴァーシティ 術後治療用in situ噴霧生体応答性免疫療法ゲル
CN108969757B (zh) * 2018-07-11 2021-07-27 浙江大学 负载microRNA的氧化铈纳米复合水凝胶及制备方法和应用
CN110498607B (zh) * 2019-08-21 2022-03-08 中国科学院上海硅酸盐研究所 一种多功能钙硅基稀土掺杂的生物活性粉体及其制备方法和应用

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WO2011151631A1 (en) * 2010-06-04 2011-12-08 King's College London Nanoparticles and their uses in molecular imaging
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Also Published As

Publication number Publication date
EA201592279A1 (ru) 2016-06-30
EP3003288A1 (en) 2016-04-13
MX2015016456A (es) 2016-03-03
WO2014191569A1 (en) 2014-12-04
US20160184225A1 (en) 2016-06-30
MX376269B (es) 2025-03-07
UA116380C2 (uk) 2018-03-12
US11357724B2 (en) 2022-06-14
HK1222563A1 (zh) 2017-07-07
AU2014273043B2 (en) 2019-02-07
AU2014273043A1 (en) 2015-12-03
MA38687A1 (fr) 2017-12-29
CA2913023A1 (en) 2014-12-04
KR20160013212A (ko) 2016-02-03
CN112107558A (zh) 2020-12-22
JP6387400B2 (ja) 2018-09-05
US10413509B2 (en) 2019-09-17
ZA201509307B (en) 2017-04-26
BR112015029853A2 (pt) 2017-07-25
NZ714273A (en) 2019-04-26
KR102245421B1 (ko) 2021-04-29
CA2913023C (en) 2021-06-08
US20200009050A1 (en) 2020-01-09
JP2016522833A (ja) 2016-08-04
SG11201509436TA (en) 2015-12-30
CN105407878A (zh) 2016-03-16

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