CN112068302A - Pathological section microscopic detection device capable of reducing pollution - Google Patents
Pathological section microscopic detection device capable of reducing pollution Download PDFInfo
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- CN112068302A CN112068302A CN202010996101.4A CN202010996101A CN112068302A CN 112068302 A CN112068302 A CN 112068302A CN 202010996101 A CN202010996101 A CN 202010996101A CN 112068302 A CN112068302 A CN 112068302A
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/241—Devices for focusing
- G02B21/242—Devices for focusing with coarse and fine adjustment mechanism
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/32—Micromanipulators structurally combined with microscopes
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
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Abstract
The invention belongs to the technical field of medical detection equipment, and particularly relates to a pathological section microscopic detection device capable of reducing pollution. Comprises a microscope body used for carrying out microscopic detection on pathological sections; a holder for placement in proximity to an objective lens of a microscope body; the transportation rail is arranged on the bracket and is parallel to the objective table of the microscope body; the slide glass bearing frames are arranged on the conveying track and can move to the position right above the light through hole between the objective lens and the objective table of the microscope body along the conveying track; a drive device mounted on the slide carrier for driving the slide carrier to move along the transport track; and the controller is connected with the driving device and is used for controlling the driving device to work. The device can effectively reduce the contact frequency of an operator and a microscope and reduce the pollution of the microscope in the process of detecting pathological sections.
Description
Technical Field
The invention belongs to the technical field of medical detection equipment, and particularly relates to a pathological section microscopic detection device capable of reducing pollution.
Background
The pathological section is prepared by taking pathological tissues with a certain size and using a histopathology method. The diseased tissue is typically embedded in paraffin blocks, sliced with a microtome, stained with hematoxylin-eosin, and further examined microscopically for lesions. And finally making pathological diagnosis according to the occurrence and development processes of the pathological changes.
In the existing medical experiment process, corresponding pathological sections are prepared according to requirements, then manual observation is carried out by using a microscope, the objective table can only be used for placing one glass slide at a time, the glass slide needs to be continuously replaced, and the focal length of the microscope is adjusted, so that detection and observation of more sample sizes are conveniently completed. However, in the process, the number of times of contacting the microscope by hands is very large, and reagents such as dye and the like stained on the hands in the experimental process are easy to cause microscope pollution. It is therefore desirable to develop a microscope observation device that can reduce the number of contacts.
Disclosure of Invention
In order to solve the technical problem, the invention provides a pathological section microscopic detection device capable of reducing pollution.
The invention aims to provide a pathological section microscopic detection device capable of reducing pollution, which comprises a microscope body, wherein the microscope body comprises an objective lens, an objective table, a fine focusing screw, a coarse focusing screw and a quasi focusing screw,
a holder for placement in proximity to an objective lens of the microscope body;
a transport rail mounted on the support and parallel to the stage, a portion of the transport rail being positioned for placement between the objective lens and the aperture of the stage;
a plurality of slide carriers which are arranged on the transportation track and can move along the transportation track to be right above the light through hole between the objective lens and the objective table;
a drive device mounted on the slide carrier for driving the slide carrier to move along the transport track;
and the controller is connected with the driving device and is used for controlling the driving device to work.
Preferably, in the pathological section microscopic examination device capable of reducing contamination, the slide glass carrier is an annular frame or a U-shaped frame, and the bottom of the slide glass carrier can be magnetically attracted to the stage.
Preferably, in the pathological section microscopic detection device capable of reducing pollution, the inner side of the annular frame or the U-shaped frame is in a step shape, and the glass slide can be placed on the step in the step shape.
Preferably, the pathological section microscopic examination device capable of reducing pollution further comprises an elastic sheet for fixing the slide, wherein the elastic sheet is arranged on the side edge of the slide bearing frame.
Preferably, the pathological section microscopic examination device capable of reducing pollution comprises two annular tracks which are concentrically arranged, or comprises two straight tracks which are arranged in parallel.
Preferably, in the pathological section microscopic detection device capable of reducing pollution, the driving device is a roller with a roller rotating motor; the roller is used for moving along the transportation track;
the drive means is mounted on the or each slide carrier at the foremost position of the queue.
Preferably, the pathological section microscopic examination device capable of reducing pollution further comprises,
a fine focus-aligning bidirectional rotary motor mounted on the fine rotary screw;
a coarse focusing bi-directional rotating motor mounted on the coarse focusing screw;
the controller is respectively electrically connected with the fine focusing bidirectional rotating motor and the coarse focusing bidirectional rotating motor and is used for controlling the fine focusing bidirectional rotating motor and the coarse focusing bidirectional rotating motor to work.
Preferably, the pathological section microscopic detection device capable of reducing pollution further comprises two transverse grooves with openings on the upper surfaces, the transverse grooves are arranged on the object stage and are respectively located on two sides of the light through hole, and the transverse grooves are correspondingly connected with the transportation track in a penetrating mode.
Compared with the prior art, the pathological section microscopic detection device capable of reducing pollution provided by the invention has the following beneficial effects:
1. the invention uses the camera to shoot the picture to be microscopically detected, the slide sample to be microscopically detected and the like are placed on the slide bearing frames, the slide bearing frames are arranged on the transportation track, the switch panel switches control the corresponding roller rotating motors to work, the slide is driven to move to be positioned right above the light through hole, the thick focusing screw or the thin focusing screw is controlled to rotate in the positive and negative directions, and the clear picture is displayed on the computer display. In the process of detecting pathological sections by using the device, the hands of an operator only contact with the coarse and fine quasi-focus screws which are easy to clean, and do not contact with the objective table and the objective lens which is difficult to clean, so that the contact frequency of the operator and a microscope can be effectively reduced, and the pollution of the microscope is effectively reduced.
2. The invention can place a plurality of glass slides for continuous observation at one time, does not need to change the glass slides midway, does not need to frequently adjust the fine-focus turning screw and the coarse-focus alignment screw, and has high detection efficiency, high speed and simple operation.
3. According to the invention, the fine focusing bidirectional rotating motor and the coarse focusing bidirectional rotating motor are arranged, and after the corresponding fine focusing spiral and the corresponding coarse focusing spiral are controlled to rotate in the forward and reverse directions through the switch of the switch panel, the hands of an operator are not contacted with a microscope completely in the detection process, so that the pollution probability of the microscope is greatly reduced.
Drawings
FIG. 1 is a schematic structural diagram of a conventional microscope;
FIG. 2 is a schematic structural diagram of a pathological section microscopic examination device capable of reducing contamination according to the present invention;
FIG. 3 is a schematic view of the connection of the subject stage to a slide carrier of the present invention;
FIG. 4 is a schematic view of the connection of the transport track of the present invention to a slide carrier.
Detailed Description
In order that those skilled in the art will better understand the technical solutions of the present invention to be implemented, the present invention will be further described with reference to the following specific embodiments and accompanying drawings.
Example 1
The invention provides a pathological section microscopic detection device capable of reducing pollution, which comprises a microscope body 1, wherein the microscope body 1 adopts a microscope structure capable of being provided with a camera in the prior art, and comprises an ocular lens 11, a lens cone 12, a converter 13, an objective lens 14, an objective table 2, a light chopper, a reflector 15, a lens base 16, a lens column 17, a lens arm 18, a fine focusing spiral 3 and a coarse focusing spiral 4, as shown in figures 1-4. The microscope body 1 has a function of detecting and observing pathological sections. The microscope body 1 further comprises a camera capable of imaging pathological sections, and the connecting mode of the camera and the microscope body 1 can be described by referring to the installation of the camera in the prior art. And the picture shot by the camera is transmitted to the computer display for display.
The invention also comprises a slide transport device comprising a support 5, the support 5 being intended to be placed in the vicinity of the objective 14 of the microscope body 1, serving a load-bearing function. The support 5 is provided with a transportation rail 6 parallel to the objective lens 2, part of the transportation rail 6 is arranged between the objective lens 14 and the light through hole 21 of the objective lens 2, and the other parts are arranged on the side of the microscope body 1, at least two slide bearing frames 7 are arranged on the transportation rail 6, the slide bearing frames 7 can move along the transportation rail 6, each slide bearing frame 7 can move to the position right above the light through hole 21 between the objective lens 14 and the objective lens 2, the slide bearing frames 7 are used for placing the dyed pathological section, the pathological section can be laid on the slide 8, then the slide 8 is arranged on the slide bearing frames 7, and the slide 8 can move together with the slide bearing frames 7 to the position between the objective lens 14 and the objective lens 2 and right above the light through hole 21, so as to be convenient for microscopic observation.
The slide glass carrier 7 is an annular frame or a U-shaped frame, and when the slide glass carrier 7 moves to a position between the objective lens 14 and the objective table 2 and right above the light through hole 21, no other shielding object is arranged above the light through hole 21 due to the arrangement of the annular frame or the U-shaped frame, so that a sample can be conveniently observed through microscopic detection. The inner side of the annular frame or the U-shaped frame is in a step shape, and the glass slide 8 can be placed on the upper step of the step shape. Preferably, to improve the stability of the slide 8, it is mounted on the stepped shape of the annular frame with the upper surface of the slide 8 flush with the upper surface of the slide carrier 7. Preferably, in order to further improve the stability of the slide glass 8, an elastic plate 71 capable of springing open upward is attached to a side edge of the slide glass carrier 7, and the slide glass 8 is fixed by applying pressure to the elastic plate 71.
Each slide carrier 7 has mounted thereon a drive device for driving it along the transport rail 6. The driving device is a roller 61 with a roller rotating motor, the roller 61 is a universal wheel, the transportation track 6 comprises two annular tracks which are concentrically arranged, one end of the transportation track 6 is used for being placed between the objective lens 14 and the objective table 2, and the other end of the transportation track is used for being placed on the side of the microscope body 1. The slide glass carrier 7 is provided at the bottom with four rollers 61, and two rollers 61 are provided on both sides of the bottom, wherein two rollers 61 on one side are movable along the outer circular track, and two rollers 61 on the other side are movable along the inner circular track.
The slide bearing frame 7 is provided at its bottom with a magnet which can attract a magnetic member provided on the stage 2. When the roller rotation motor is started, the power of the roller rotation motor can overcome the attraction force to move the roller 61.
The mirror base 16 is provided with a controller, the controller is wirelessly connected with the roller wheel rotating motor, and the controller is also connected with a switch panel through an electric lead. And the switch panel is provided with a corresponding name switch for controlling the operation of each roller rotating motor.
When the device is used, a camera is used for shooting a picture to be microscopically detected, the coarse focusing screw 4 is controlled to enable the objective lens 14 to be far away from the objective table 2, then an operator places the bracket 5 near the objective lens 14 of the microscope body 1, part of the structure of the conveying track 6 is positioned between the objective lens 14 and the objective table 2, the rest part of the structure is positioned at the side of the microscope body 1, slide samples and the like needing to be microscopically detected are placed on the slide bearing frames 7, then the slide bearing frames 7 are arranged on the conveying track 6, each roller rotating motor corresponds to one switch, the operator controls the corresponding roller rotating motor to work through the switch panel switch to drive the slide 8 corresponding to the roller rotating motor to move to be positioned right above the light through hole 21, then the coarse focusing screw 4 or the fine focusing screw 3 is controlled to rotate forwards and backwards, so that a clear picture is displayed on a computer display, then the photo record is taken. In the whole testing process, the operator hand only contacts with easy abluent thick accurate burnt spiral 4 or thin commentaries on classics burnt spiral 3, does not contact with objective table and difficult abluent objective 14, can effectively reduce the microscope and pollute, and puts a plurality of slide glass 8 once and can observe in succession, need not change slide glass 8 midway, easy operation, it is efficient.
After the position of the first slide carrier 7 is adjusted, since a distance is left between the objective lens 14 and the stage 2, and the next slide carrier 7 pushes the previous slide carrier 7 to move forward along the conveying track, we can detect and observe the next slide 8 only by controlling the objective slide 8 to be observed to move to a specific position. And because the position of the ocular lens 11 is fixed, the microscopic picture is still clear, and only fine adjustment is needed, so that the problem that the fine focusing screw 3 and the coarse focusing screw 4 are frequently adjusted due to frequent manual replacement of the glass slide 8 is solved, and the detection efficiency is improved. The slide glass bearing frame 7 is transported and moved in the horizontal plane of the transportation track 6, even if the distance between the objective lens 14 and the objective table 2 is small, the distance between the objective lens and the objective table only needs to be finely adjusted, the slide glass bearing frame 7 can be ensured to pass through the distance to obtain a clear image, the adjustment range is small, and the adjustment speed is high.
Example 2
The transportation track 6 comprises two straight tracks which are arranged in parallel, the middle part of the transportation track 6 is used for being placed between the objective lens 14 and the object stage 2, and other parts are used for being placed on two sides of the microscope body 1. The driving device is a movable wheel with a roller wheel rotating motor, four movable wheels are arranged at the bottom of the slide glass bearing frame 7, two movable wheels are respectively arranged at the bottom, and the movable wheels can move along a straight track at the same side of the slide glass bearing frame.
The rest of the structure and the operation principle of embodiment 2 are the same as those of embodiment 1.
Example 3
The structure and the working principle of the embodiment 3 are basically the same as those of the embodiment 1, except that only the rollers 61 of the slide glass bearing frame 7 positioned at the forefront of the queue are provided with roller rotating motors, the rest slide glass bearing frames 7 are detachably hung together through hooks in sequence, and the controller is also connected with a switch for controlling the roller rotating motors through electric leads. When the next observation object needs to be changed, the movement of the foremost slide bearing frame 7 is controlled, and the movement of the rear slide bearing frame 7 can be driven.
Example 4
In order to further improve the efficiency and avoid pollution, install on the thin burnt spiral 3 and be used for controlling its pivoted thin accurate burnt two-way rotating electrical machines 31, install on the thick accurate burnt spiral 4 and be used for controlling its pivoted thick accurate burnt two-way rotating electrical machines 41, the controller respectively with thin accurate burnt two-way rotating electrical machines 31, thick accurate burnt two-way rotating electrical machines 41 electricity is connected, install the corresponding name switch that controls thin accurate burnt two-way rotating electrical machines 31, thick accurate burnt two-way rotating electrical machines 41, each gyro wheel rotating electrical machines work respectively on the switch panel. The coarse focusing screw 4 is controlled by the switch panel when the objective lens 14 needs to be moved away from the stage 2. When a clear picture is required to be displayed on the computer display, the switch panel is used for controlling the forward and reverse rotation of the coarse focusing bidirectional rotating motor 41 or the fine focusing bidirectional rotating motor 31. The rest of the structure and the operation principle of embodiment 4 are the same as those of embodiment 1.
This embodiment is through setting up thin accurate focus two-way rotating electrical machines 31, thick accurate focus two-way rotating electrical machines 41, through the corresponding thin rotation of switch panel switch control spiral 3, thick accurate focus spiral 4 forward and reverse rotation, operator's hand is not contacted with the microscope completely, very big reduction microscope pollution probability.
Example 5
In order to improve the stability of the device, the two sides of the object stage 2, which are located at the light-passing hole 21, are both provided with transverse grooves 22 with openings on the upper surfaces, wherein one transverse groove 22 is used for one rail of the transportation rail 6 to pass through, and the other rail of the transportation rail 6 of the other transverse groove 22 to pass through. The surfaces of the transport rails 6 that are in contact with the transverse grooves 22 are each provided with a magnetic member, such as a magnet. Thus, the transportation rail 6 is fixed on the object stage 2, and the stability of the device is good.
The rest of the structure and the operation principle of embodiment 5 are the same as those of embodiment 1.
It should be noted that, the connection relation of the components not specifically mentioned in the present invention is the default of the prior art, and the connection relation of the structures is not described in detail since it does not relate to the invention point and is a common application of the prior art.
It should be noted that while the preferred embodiments of the present invention have been described, additional variations and modifications of these embodiments may occur to those skilled in the art once they learn of the basic inventive concepts. Therefore, it is intended that the appended claims be interpreted as including preferred embodiments and all such alterations and modifications as fall within the scope of the invention.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.
Claims (8)
1. A pathological section microscopic detection device capable of reducing pollution comprises a microscope body (1), wherein the microscope body (1) comprises an objective lens (14), an objective table (2), a fine focusing spiral (3) and a coarse focusing spiral (4), and is characterized by further comprising,
a holder (5) for placing in the vicinity of an objective (14) of the microscope body (1);
a transport rail (6) mounted on the carriage (5) and parallel to the object table (2), a part of the transport rail (6) being positioned for placement between the objective (14) and a clear aperture (21) of the object table (2);
a plurality of slide carriers (7) which are arranged on the transport track (6) and can move along the transport track (6) to be positioned right above a light passing hole (21) between the objective lens (14) and the object stage (2);
-drive means mounted on the slide carrier (7) for driving the slide carrier (7) along the transport track (6);
and the controller is connected with the driving device and is used for controlling the driving device to work.
2. The microscopic examination apparatus for pathological sections with reduced contamination according to claim 1, wherein the slide carrier (7) is a ring-shaped or U-shaped frame and has a bottom that is magnetically attracted to the stage (2).
3. The microscopic examination apparatus for pathological sections with reduced contamination according to claim 2, characterized in that the inside of the ring-shaped or U-shaped frame is in the shape of a step, on which a slide (8) can be placed.
4. The microscopic examination apparatus for pathological sections with reduced contamination according to claim 3, further comprising an elastic sheet (71) for fixing the slide (8) and installed on the side edge of the slide carrier (7).
5. The microscopic examination apparatus for pathological sections with reduced contamination according to claim 1, wherein the transportation rail (6) comprises two circular rails disposed concentrically or two straight rails disposed in parallel.
6. The microscopic examination apparatus for pathological section capable of reducing contamination according to claim 5, wherein the driving means is a roller (61) with a roller rotating motor; the rollers (61) are used for moving along the transportation track (6);
the drive means is mounted on the slide carrier (7) at the foremost position of the queue or on each slide carrier (7).
7. The microscopic examination apparatus for pathological section capable of reducing contamination according to claim 1, further comprising,
a fine focus-alignment bidirectional rotary motor (31) mounted on the fine focus turning screw (3);
a coarse focusing bi-directional rotating motor (41) mounted on the coarse focusing screw (4);
the controller is respectively electrically connected with the fine focusing bidirectional rotating motor (31) and the coarse focusing bidirectional rotating motor (41) and is used for controlling the fine focusing bidirectional rotating motor and the coarse focusing bidirectional rotating motor to work.
8. The microscopic examination device for pathological sections capable of reducing pollution according to claim 1, further comprising two lateral grooves (22) with openings on the upper surface, which are opened on the stage (2) and respectively located on two sides of the light through hole (21), wherein the lateral grooves (22) are correspondingly crossed with the transportation track (6).
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN113572912A (en) * | 2021-07-03 | 2021-10-29 | 冯浩 | Remote transmission method of digital pathological section |
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