CN112057046A - Tumor fluorescence imaging spectrum diagnostic apparatus - Google Patents

Tumor fluorescence imaging spectrum diagnostic apparatus Download PDF

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Publication number
CN112057046A
CN112057046A CN202010946545.7A CN202010946545A CN112057046A CN 112057046 A CN112057046 A CN 112057046A CN 202010946545 A CN202010946545 A CN 202010946545A CN 112057046 A CN112057046 A CN 112057046A
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CN
China
Prior art keywords
fluorescence
tumor
diagnostic apparatus
light source
imaging
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Pending
Application number
CN202010946545.7A
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Chinese (zh)
Inventor
蔡惠明
李长流
倪轲娜
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Nanjing Nuoyuan Medical Devices Co Ltd
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Nanjing Nuoyuan Medical Devices Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Nanjing Nuoyuan Medical Devices Co Ltd filed Critical Nanjing Nuoyuan Medical Devices Co Ltd
Priority to CN202010946545.7A priority Critical patent/CN112057046A/en
Publication of CN112057046A publication Critical patent/CN112057046A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/01Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue

Abstract

The invention discloses a tumor fluorescence imaging spectrum diagnostic apparatus, which comprises a light source, a diaphragm regulator, a beam expanding device, a bracket, a fluorescence collecting device, an imaging device, a display screen, a temperature detecting device and a microprocessor, wherein the light source, the diaphragm regulator, the beam expanding device, the fluorescence collecting device, the imaging device, the display screen and the temperature detecting device are in signal connection with the microprocessor; the light source, the diaphragm regulator and the beam expanding device are all connected to the support in a sliding mode and can slide along the horizontal direction, and light rays emitted by the light source sequentially pass through the diaphragm regulator and the beam expanding device to reach tumor tissues; the imaging device is respectively in signal connection with the fluorescence collecting device and the display screen, and the fluorescence collecting device is used for collecting fluorescence generated by tumor tissues and transmitting the collected fluorescence to the imaging device; the temperature detection device is used for detecting the temperature of the tumor tissue, and if the temperature of the tumor tissue exceeds the preset temperature, the microprocessor cuts off the power supply after receiving a signal sent by the temperature detection device.

Description

Tumor fluorescence imaging spectrum diagnostic apparatus
Technical Field
The invention relates to the field of medical treatment, in particular to a tumor fluorescence imaging spectrum diagnostic apparatus.
Background
With the development of society and the change of living habits of people, more and more people suffer from tumors, so that the diagnosis of tumors is more and more important. The existing tumor diagnosis equipment is heavy and has low diagnosis efficiency; the fluorescence diagnosis is to utilize the tumor tissue to generate fluorescence under the excitation of light with certain wavelength, and obtain a diagnosis result by receiving the generated fluorescence and analyzing the spectral characteristics of the fluorescence; however, in the prior art, only partial regions of tumor tissues can be diagnosed one by one, which is easy to cause misdiagnosis; even when diagnosis is performed, burn may be caused to the patient by irradiating the patient's tumor tissue. Therefore, the invention provides a tumor fluorescence imaging spectrum diagnostic apparatus to solve the problems in the prior art.
Disclosure of Invention
The invention aims to provide a tumor fluorescence imaging spectrum diagnostic apparatus, and aims to solve the problems that the tumor tissue area is difficult to be comprehensively diagnosed and the burn of a patient is easily caused in the prior art.
In order to achieve the purpose, the invention provides a tumor fluorescence imaging spectrum diagnostic apparatus, which is characterized in that: the device comprises a light source, a diaphragm regulator, a beam expanding device, a support, a fluorescence collecting device, an imaging device, a display screen, a temperature detecting device and a microprocessor, wherein the light source, the diaphragm regulator, the beam expanding device, the fluorescence collecting device, the imaging device, the display screen and the temperature detecting device are in signal connection with the microprocessor; the light source, the diaphragm regulator and the beam expanding device are all connected to the support in a sliding mode and can slide along the horizontal direction, and light rays emitted by the light source sequentially pass through the diaphragm regulator and the beam expanding device to reach tumor tissues; the imaging device is respectively in signal connection with the fluorescence collecting device and the display screen, and the fluorescence collecting device is used for collecting fluorescence generated by tumor tissues and transmitting the collected fluorescence to the imaging device; the temperature detection device is used for detecting the temperature of the tumor tissue, and if the temperature of the tumor tissue exceeds the preset temperature, the microprocessor receives a signal sent by the temperature detection device and then turns off the light source.
Preferably, the light source is a laser.
Preferably, the beam expanding device includes a concave lens and a convex lens, and a distance between the concave lens and the convex lens is adjustable.
Preferably, a motor is further included for adjusting a distance between the concave lens and the convex lens.
Preferably, the fluorescence collecting device is connected with the imaging device through an optical fiber.
Preferably, the diaphragm regulator is connected with the beam expanding device through an optical fiber.
Preferably, the imaging device comprises a memory device in signal connection with the microprocessor for storing the imaging information.
Preferably, the temperature detection device is an infrared sensor.
Preferably, the device further comprises an alarm which is in signal connection with the infrared sensor.
Preferably, the bracket is provided with rollers.
Compared with the prior art, the invention has the advantages that:
the tumor fluorescence imaging spectrum diagnostic apparatus can be used for comprehensively diagnosing the tumor tissue area, is convenient to operate and can not burn a patient.
Drawings
Fig. 1 is a schematic diagram of the tumor fluorescence imaging spectrum diagnostic apparatus of the present invention.
The reference numbers in the figures illustrate:
1. a light source; 2. a diaphragm adjuster; 3. a support; 4. a beam expanding device; 5. a temperature detection device; 6. a fluorescence collection device; 7. an imaging device; 8. a display screen; 9. a microprocessor; 10. tumor tissue.
Detailed Description
The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention; it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments, and all other embodiments obtained by those skilled in the art without any inventive work are within the scope of the present invention.
In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "top/bottom", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise specifically stated or limited, the terms "mounted," "disposed," "sleeved/connected," "connected," and the like are used in a broad sense, and for example, "connected" may be a fixed connection, a detachable connection, an integral connection, a mechanical connection, an electrical connection, a direct connection, an indirect connection through an intermediate medium, and a communication between two elements.
Referring to fig. 1, a fluorescence imaging spectrum diagnostic apparatus for tumor includes a light source 1, a diaphragm adjuster 2, a beam expander 4, a bracket 3, a fluorescence collecting device 6, an imaging device 7, a display screen 8, a temperature detecting device 5 and a microprocessor 9, wherein the light source 1, the diaphragm adjuster 2, the beam expander 4, the fluorescence collecting device 6, the imaging device 7, the display screen 8 and the temperature detecting device 5 are all in signal connection with the microprocessor 9; the light source 1, the diaphragm regulator 2 and the beam expanding device 4 are all connected to the support 3 in a sliding mode and can slide along the horizontal direction, and light rays emitted by the light source 1 sequentially pass through the diaphragm regulator 2 and the beam expanding device 4 to the tumor tissue 10; the imaging device 7 is respectively connected with the fluorescence collecting device 6 and the display screen 8 through signals, the fluorescence collecting device 6 is used for collecting the fluorescence generated by the tumor tissue 10 and transmitting the collected fluorescence to the imaging device 7; the temperature detection device 5 is used for detecting the temperature of the tumor tissue 10, and if the temperature of the tumor tissue 10 exceeds a preset temperature, the microprocessor 9 receives a signal sent by the temperature detection device 5 and then turns off the light source 1.
Preferably, the light source 1 is a laser; the laser emits light which enters the beam expanding device 4 through the diaphragm adjuster 2; the diaphragm regulator 2 is connected with the beam expanding device 4 through an optical fiber; the beam expanding device 4 expands the beam to irradiate the tumor tissue 10 area of the patient; the microprocessor 9 makes adjustments to the iris adjuster 2 to initially control the range of incident light as required for diagnostics.
Meanwhile, in order to match the incident light to the tumor tissue 10 areas of different patients, the light needs to be expanded by the beam expander 4. The beam expanding device 4 comprises a concave lens and a convex lens, and the distance between the concave lens and the convex lens can be adjusted; in order to improve the efficiency, the tumor fluorescence imaging spectrum diagnostic apparatus further comprises a motor (not shown), and the motor can adjust the distance between the concave lens and the convex lens after receiving the instruction sent by the microprocessor 9.
Furthermore, in order to adapt to the conditions of different patients, a sliding rail (not shown) is arranged on the support 3, the light source 1, the diaphragm adjuster 2 and the beam expander 4 are respectively connected to the support 3 in a sliding manner through the sliding rail and can slide along the horizontal direction, and light emitted by the light source 1 is adjusted by the diaphragm adjuster 2 and the beam expander 4 in sequence and then irradiates the region of the tumor tissue 10.
The fluorescence collection device 6 is preferably a camera which receives the fluorescence emitted by the tumor tissue 10 and transmits the fluorescence to the imaging device 7 through an optical fiber; the imaging device 7 displays the imaged image on the display screen 8 for reference by the doctor.
The imaging means 7 comprise memory means in signal connection with the microprocessor 9 for storing imaging information. Since the detection of the patient's tumor tissue 10 continues for a period of time, the imaging data can be saved and retrieved as needed.
In order to prevent burns to the patient, the tumor fluorescence imaging spectrum diagnostic apparatus further comprises a temperature detection device 5, the temperature detection device 5 is preferably an infrared sensor, and the infrared sensor is used for detecting the temperature of the tumor tissue 10; the tumor fluorescence imaging spectrum diagnostic apparatus also comprises an alarm which is also in signal connection with the microprocessor 9. If the infrared sensor detects that the temperature of the tumor tissue 10 exceeds the preset temperature, a signal is sent to the microprocessor 9, the microprocessor 9 closes the laser after receiving the signal sent by the infrared sensor, and simultaneously sends an instruction to the alarm, and the alarm gives an alarm.
Preferably, the carriage 3 is provided with rollers (not shown) to facilitate movement.
The tumor fluorescence imaging spectrum diagnostic apparatus of the invention can be used for comprehensively diagnosing the tumor tissue 10 area, is convenient to operate and can not burn the patient.
The foregoing is only a preferred embodiment of the present invention; the scope of the invention is not limited thereto. Any person skilled in the art should be able to cover the technical scope of the present invention by equivalent or modified solutions and modifications within the technical scope of the present invention.

Claims (10)

1. A tumor fluorescence imaging spectrum diagnostic apparatus is characterized in that: the device comprises a light source, a diaphragm regulator, a beam expanding device, a support, a fluorescence collecting device, an imaging device, a display screen, a temperature detecting device and a microprocessor, wherein the light source, the diaphragm regulator, the beam expanding device, the fluorescence collecting device, the imaging device, the display screen and the temperature detecting device are in signal connection with the microprocessor; the light source, the diaphragm regulator and the beam expanding device are all connected to the support in a sliding mode and can slide along the horizontal direction, and light rays emitted by the light source sequentially pass through the diaphragm regulator and the beam expanding device to reach tumor tissues; the imaging device is respectively in signal connection with the fluorescence collecting device and the display screen, and the fluorescence collecting device is used for collecting fluorescence generated by tumor tissues and transmitting the collected fluorescence to the imaging device; the temperature detection device is used for detecting the temperature of the tumor tissue, and if the temperature of the tumor tissue exceeds the preset temperature, the microprocessor receives a signal sent by the temperature detection device and then turns off the light source.
2. The tumor fluorescence imaging spectrum diagnostic apparatus according to claim 1, characterized in that: the light source is a laser.
3. The tumor fluorescence imaging spectrum diagnostic apparatus according to claim 1, characterized in that: the beam expanding device comprises a concave lens and a convex lens, and the distance between the concave lens and the convex lens can be adjusted.
4. The tumor fluorescence imaging spectrum diagnostic apparatus according to claim 3, characterized in that: and a motor for adjusting a distance between the concave lens and the convex lens.
5. The tumor fluorescence imaging spectrum diagnostic apparatus according to claim 1, characterized in that: the fluorescence collecting device is connected with the imaging device through an optical fiber.
6. The tumor fluorescence imaging spectrum diagnostic apparatus according to claim 1, characterized in that: and the diaphragm regulator is connected with the beam expanding device through an optical fiber.
7. The tumor fluorescence imaging spectrum diagnostic apparatus according to claim 1, characterized in that: the imaging device comprises a storage device which is in signal connection with the microprocessor and is used for storing imaging information.
8. The tumor fluorescence imaging spectrum diagnostic apparatus according to claim 1, characterized in that: the temperature detection device is an infrared sensor.
9. The tumor fluorescence imaging spectrum diagnostic apparatus according to claim 8, characterized in that: the alarm is in signal connection with the microprocessor.
10. The tumor fluorescence imaging spectrum diagnostic apparatus according to claim 1, characterized in that: the support is provided with a roller.
CN202010946545.7A 2020-09-10 2020-09-10 Tumor fluorescence imaging spectrum diagnostic apparatus Pending CN112057046A (en)

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Application Number Priority Date Filing Date Title
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Cited By (1)

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CN114391792A (en) * 2021-09-13 2022-04-26 南京诺源医疗器械有限公司 Tumor prediction method and device based on narrow-band imaging and imaging endoscope

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Application publication date: 20201211