CN112028985A - 基因工程生长因子变异体 - Google Patents
基因工程生长因子变异体 Download PDFInfo
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- CN112028985A CN112028985A CN202010915430.1A CN202010915430A CN112028985A CN 112028985 A CN112028985 A CN 112028985A CN 202010915430 A CN202010915430 A CN 202010915430A CN 112028985 A CN112028985 A CN 112028985A
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- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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| CN117736272A (zh) * | 2024-02-19 | 2024-03-22 | 四川省医学科学院·四川省人民医院 | 一种具有促成骨功能的生物活性多肽 |
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| CA2830503A1 (en) | 2011-03-17 | 2012-09-20 | Minerva Biotechnologies Corporation | Method for making pluripotent stem cells |
| EP2707021B1 (en) * | 2011-05-09 | 2024-02-21 | Minerva Biotechnologies Corporation | Genetically engineered growth factor variants |
| IL307628A (en) * | 2013-02-20 | 2023-12-01 | Minerva Biotechnologies Corp | Nme inhibitors and methods of using nme inhibitors |
| JP2018501539A (ja) * | 2014-10-16 | 2018-01-18 | カウンシル， インコーポレイテッド | バリアントコーラー |
| KR20230028796A (ko) | 2020-06-26 | 2023-03-02 | 미네르바 바이오테크놀로지 코포레이션 | 항-nme 항체 및 암 또는 암 전이의 치료 방법 |
| AU2022227686A1 (en) | 2021-02-25 | 2023-07-27 | Lyell Immunopharma, Inc. | Ror1 targeting chimeric antigen receptor |
| AU2023253692A1 (en) | 2022-04-12 | 2024-11-14 | Minerva Biotechnologies Corporation | Anti-variable muc1* antibodies and uses thereof |
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| US20060228357A1 (en) * | 2005-04-06 | 2006-10-12 | Ibc Pharmaceuticals, Inc. | Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses |
| US20070009918A1 (en) * | 1996-04-23 | 2007-01-11 | President And Fellows Of Harvard College | Methods and compositions for regulating T cell subsets by modulating transcription factor activity |
| US20090075926A1 (en) * | 2006-12-06 | 2009-03-19 | Bamdad Cynthia C | Method for identifying and manipulating cells |
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| DK0495910T3 (da) * | 1989-10-18 | 2002-01-14 | Us Health | Fremstilling og anvendelse af humant nm23-H2-protein og derimod rettede antistoffer |
| US20050112607A1 (en) * | 1999-01-23 | 2005-05-26 | Bamdad Cynthia C. | Rapid and sensitive detection of protein aggregation |
| ES2317843T3 (es) * | 1999-07-13 | 2009-05-01 | Bolder Biotechnology, Inc. | Proteinas de fusion de eritropoyetina-inmunoglobulina. |
| RU2263118C2 (ru) * | 1999-08-09 | 2005-10-27 | Лексиген Фармасьютикэлс Корп. | Комплексы антител с несколькими цитокинами |
| EP1334127A1 (en) * | 2000-11-02 | 2003-08-13 | Maxygen Aps | Single-chain multimeric polypeptides |
| US20020169290A1 (en) * | 2000-11-02 | 2002-11-14 | Claus Bornaes | New multimeric interferon beta polypeptides |
| US7829084B2 (en) * | 2001-01-17 | 2010-11-09 | Trubion Pharmaceuticals, Inc. | Binding constructs and methods for use thereof |
| AU2002306921A1 (en) * | 2001-03-27 | 2002-10-08 | Massachusetts Institute Of Technology | Methods and products related to fgf dimerization |
| EP1353182A3 (en) * | 2002-04-12 | 2004-02-04 | Smithkline Beecham Corporation | Method of predicting cell-based assay results using binding profiles |
| WO2004028551A1 (en) * | 2002-09-24 | 2004-04-08 | The Burnham Institute | Novel agents that modulate eph receptor activity |
| NZ544924A (en) * | 2003-06-27 | 2009-03-31 | Biogen Idec Inc | Modified binding molecules comprising connecting peptides |
| US20050054752A1 (en) * | 2003-09-08 | 2005-03-10 | O'brien John P. | Peptide-based diblock and triblock dispersants and diblock polymers |
| JP2008504012A (ja) * | 2004-01-28 | 2008-02-14 | シントニックス・ファーマシューティカルズ・インコーポレーテッド | 不妊治療のためのへテロ二量体卵胞刺激ホルモン−Ｆｃ（ＦＳＨ−Ｆｃ）融合タンパク質 |
| EP3805269A1 (en) * | 2006-06-12 | 2021-04-14 | Aptevo Research and Development LLC | Single-chain multivalent binding proteins with effector function |
| KR20110044992A (ko) * | 2008-07-02 | 2011-05-03 | 이머전트 프로덕트 디벨롭먼트 시애틀, 엘엘씨 | ＴＧＦ-β 길항제 다중-표적 결합 단백질 |
| US11898160B2 (en) * | 2008-10-09 | 2024-02-13 | Minerva Biotechnologies Corporation | Method for maintaining pluripotency in cells |
| KR20190122749A (ko) * | 2009-06-11 | 2019-10-30 | 미네르바 바이오테크놀로지 코포레이션 | 줄기세포 및 전구세포를 배양하는 방법 |
| US20130040845A1 (en) * | 2010-02-16 | 2013-02-14 | Immune Disease Institute, Inc. | Method for screening receptors/ligands interactions |
| CA2830503A1 (en) * | 2011-03-17 | 2012-09-20 | Minerva Biotechnologies Corporation | Method for making pluripotent stem cells |
| EP2707021B1 (en) * | 2011-05-09 | 2024-02-21 | Minerva Biotechnologies Corporation | Genetically engineered growth factor variants |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070009918A1 (en) * | 1996-04-23 | 2007-01-11 | President And Fellows Of Harvard College | Methods and compositions for regulating T cell subsets by modulating transcription factor activity |
| US20060228357A1 (en) * | 2005-04-06 | 2006-10-12 | Ibc Pharmaceuticals, Inc. | Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses |
| US20090075926A1 (en) * | 2006-12-06 | 2009-03-19 | Bamdad Cynthia C | Method for identifying and manipulating cells |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117736272A (zh) * | 2024-02-19 | 2024-03-22 | 四川省医学科学院·四川省人民医院 | 一种具有促成骨功能的生物活性多肽 |
| CN117736272B (zh) * | 2024-02-19 | 2024-04-30 | 四川省医学科学院·四川省人民医院 | 一种具有促成骨功能的生物活性多肽 |
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| US20200062812A1 (en) | 2020-02-27 |
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| JP2024056702A (ja) | 2024-04-23 |
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