CN112004805B - 5,5-二取代-4,5-二氢异噁唑的制造方法 - Google Patents

5,5-二取代-4,5-二氢异噁唑的制造方法 Download PDF

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Publication number
CN112004805B
CN112004805B CN201980025644.7A CN201980025644A CN112004805B CN 112004805 B CN112004805 B CN 112004805B CN 201980025644 A CN201980025644 A CN 201980025644A CN 112004805 B CN112004805 B CN 112004805B
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acid
hydroxylamine
formula
compound
reaction
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CN112004805A (zh
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永田俊浩
志鎌大介
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Kumiai Chemical Industry Co Ltd
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Kumiai Chemical Industry Co Ltd
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/0231Halogen-containing compounds
    • B01J31/0232Halogen-containing compounds also containing elements or functional groups covered by B01J31/0201 - B01J31/0228
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/0234Nitrogen-, phosphorus-, arsenic- or antimony-containing compounds
    • B01J31/0235Nitrogen containing compounds
    • B01J31/0237Amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/30Addition reactions at carbon centres, i.e. to either C-C or C-X multiple bonds
    • B01J2231/34Other additions, e.g. Monsanto-type carbonylations, addition to 1,2-C=X or 1,2-C-X triplebonds, additions to 1,4-C=C-C=X or 1,4-C=-C-X triple bonds with X, e.g. O, S, NH/N
    • B01J2231/3481,4-additions, e.g. conjugate additions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/001General concepts, e.g. reviews, relating to catalyst systems and methods of making them, the concept being defined by a common material or method/theory
    • B01J2531/002Materials
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B61/00Other general methods

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CN201980025644.7A 2018-04-27 2019-04-24 5,5-二取代-4,5-二氢异噁唑的制造方法 Active CN112004805B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018-086679 2018-04-27
JP2018086679 2018-04-27
PCT/JP2019/017459 WO2019208643A1 (ja) 2018-04-27 2019-04-24 5,5-ジ置換-4,5-ジヒドロイソオキサゾールの製造方法

Publications (2)

Publication Number Publication Date
CN112004805A CN112004805A (zh) 2020-11-27
CN112004805B true CN112004805B (zh) 2024-06-14

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US (1) US11753384B2 (https=)
EP (1) EP3789382B1 (https=)
JP (1) JP7242641B2 (https=)
CN (1) CN112004805B (https=)
IL (1) IL278229B2 (https=)
MX (1) MX2020011267A (https=)
TW (1) TWI810284B (https=)
WO (1) WO2019208643A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3725782B1 (en) * 2017-12-15 2022-06-22 Kumiai Chemical Industry Co., Ltd. Novel method for producing 5,5-disubstituted-4,5-dihydroisoxazole
TWI844692B (zh) * 2019-06-14 2024-06-11 日商組合化學工業股份有限公司 二氫異噁唑的製造方法
CN114644602B (zh) * 2020-12-17 2024-09-03 帕潘纳(北京)科技有限公司 二氢异噁唑类化合物的制备方法
CN115073390B (zh) * 2021-03-11 2024-08-06 山东润博生物科技有限公司 一种4,5-二氢异噁唑衍生物及其制备方法和应用
CN116178294A (zh) * 2023-01-08 2023-05-30 湖南吴赣药业有限公司 一种制备5,5-二甲基-4,5-二氢异噁唑的方法
CN117285479B (zh) * 2023-09-26 2024-07-23 山东滨农科技有限公司 一种3-氯-5,5-二甲基-4,5-二氢异噁唑的制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102666503A (zh) * 2009-11-26 2012-09-12 巴斯夫欧洲公司 生产5,5-二取代的2-异噁唑啉的方法
CN103228636A (zh) * 2010-10-30 2013-07-31 印度鲁宾有限公司 噁唑及异噁唑钙释放激活的钙调节剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3329800A (en) 1999-03-29 2000-10-16 Nippon Soda Co., Ltd. Process for the preparation of (e)-3-(1-propenyl)isoxazoline
JP4465133B2 (ja) 2001-02-08 2010-05-19 クミアイ化学工業株式会社 イソオキサゾリン誘導体及びこれを有効成分とする除草剤
TWI600639B (zh) * 2007-08-17 2017-10-01 杜邦股份有限公司 製備5-鹵烷基-4,5-二氫異唑衍生物之化合物
CN107652245B (zh) * 2017-08-24 2019-09-13 郑州手性药物研究院有限公司 手性双苯噁唑酸乙酯化合物及其制备方法和应用
EP3725782B1 (en) * 2017-12-15 2022-06-22 Kumiai Chemical Industry Co., Ltd. Novel method for producing 5,5-disubstituted-4,5-dihydroisoxazole

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102666503A (zh) * 2009-11-26 2012-09-12 巴斯夫欧洲公司 生产5,5-二取代的2-异噁唑啉的方法
CN103228636A (zh) * 2010-10-30 2013-07-31 印度鲁宾有限公司 噁唑及异噁唑钙释放激活的钙调节剂

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Publication number Publication date
EP3789382A4 (en) 2021-11-24
US11753384B2 (en) 2023-09-12
EP3789382A1 (en) 2021-03-10
JPWO2019208643A1 (ja) 2021-05-13
BR112020021818A2 (pt) 2021-02-23
IL278229A (https=) 2020-12-31
IL278229B1 (en) 2023-07-01
EP3789382B1 (en) 2023-07-05
MX2020011267A (es) 2020-11-12
US20210238150A1 (en) 2021-08-05
WO2019208643A1 (ja) 2019-10-31
CN112004805A (zh) 2020-11-27
JP7242641B2 (ja) 2023-03-20
TWI810284B (zh) 2023-08-01
TW201945347A (zh) 2019-12-01
IL278229B2 (en) 2023-11-01

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