CN111991431A

CN111991431A - A liniment for treating alopecia areata and its preparation method

Info

Publication number: CN111991431A
Application number: CN202010873264.3A
Authority: CN
Inventors: 陈广生
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-08-26
Filing date: 2020-08-26
Publication date: 2020-11-27

Abstract

A liniment for treating alopecia areata and a preparation method thereof are disclosed, wherein sodium benzoate, salicylic acid and pseudolarix is used as main components, ethanol is used as an auxiliary additive, the liniment for treating alopecia areata is prepared, when the liniment is used for treating alopecia areata, the salicylic acid has the effects of inhibiting bacteria and dissolving cutin, the whole body of the liniment is weakly acidic, the benzoic acid is formed in the mixed liniment by the sodium benzoate, the benzoic acid and the salicylic acid in the liniment have the effects of inhibiting bacteria and activating scalp cutin, the active ingredients in the pseudolarix have the effects of dispelling wind, removing dampness, sterilizing and relieving itching, the sodium benzoate, the salicylic acid and the pseudolarix have synergistic effect when being combined, so that fungi parasitic on the surface of hair and inside hair follicles can be inhibited and killed, the irritation to hair follicles in the scalp is small, and the toxic and side effects to human bodies are low.

Description

A liniment for treating alopecia areata and its preparation method

Technical Field

The invention relates to the technical field of medicinal paints, in particular to a paint for treating alopecia areata and a preparation method thereof.

Background

Alopecia areata is an autoimmune non-cicatricial alopecia, usually occurs in a part with hairs of a body, local skin is normal and has no subjective symptoms, causes of alopecia areata are complex, the alopecia areata is considered to be a pathogenesis of autoimmunity of a patient at present, tinea corporis exists on the skin or metabolic circulation at the local skin is obstructed, blood supply deficiency of hair follicles causes alopecia areata and even almost all hairs fall off, and treatment in the field of traditional Chinese medicine is mainly to tonify kidney, nourish blood, activate blood and repair immune cells.

At present, the treatment of alopecia areata is difficult, a radical treatment method is not available in western medicine, and the medicines for treating alopecia areata in the prior art comprise hair growth promoting essence, alopecia areata pills and the like, but the treatment effect is not obvious, the treatment period is long, and the purpose of treating the root cause cannot be achieved.

Disclosure of Invention

Based on the situation, the paint for treating alopecia areata and the preparation method thereof are needed.

The technical scheme for solving the technical problems is as follows: a lotion for treating alopecia areata comprising:

in one embodiment, further comprising: 3 to 10 parts by mass of deionized water.

In one embodiment, the mass part of the pseudolarix is 17-23 parts.

In one embodiment, the sodium benzoate is 8 to 10 parts by mass.

In one embodiment, the salicylic acid is 8-14 parts by weight.

In one embodiment, the volume fraction of ethanol is 70% to 78%.

A method for preparing a liniment for treating alopecia areata comprises:

grinding cortex pseudolaricis into powder, soaking in ethanol, and filtering to obtain cortex pseudolaricis ethanol extract;

dissolving sodium benzoate in deionized water to obtain a sodium benzoate solution;

dissolving salicylic acid in ethanol to obtain a salicylic acid solution;

and uniformly mixing the alcohol extract of the pseudolarix, the sodium benzoate solution and the salicylic acid solution to obtain the liniment for treating alopecia areata.

In one embodiment, the pseudolarix is ground into powder, then soaked in ethanol and filtered to obtain an alcoholic pseudolarix extract comprising:

the preparation method comprises the steps of putting the pseudolarix into a grinding machine for grinding to obtain pseudolarix powder with the particle size of 50-75 um, weighing the pseudolarix powder according to a formula proportion, putting the pseudolarix powder into a stirring machine, adding ethanol, stirring at the speed of 200-300 r/min for 3-5 min, standing at room temperature, soaking for 24-60 hours, and finally filtering to obtain the pseudolarix alcohol extract.

The invention has the beneficial effects that: the invention provides a liniment for treating alopecia areata and a preparation method thereof, wherein sodium benzoate, salicylic acid and pseudolarix is used as main components, ethanol is used as an auxiliary aid to prepare the liniment for treating alopecia areata, the salicylic acid has the functions of inhibiting bacteria and dissolving cutin when used for treating alopecia areata, the whole liniment is weakly acidic, the benzoic acid is formed in the mixed liniment by the sodium benzoate, the salicylic acid and the liniment play the roles of inhibiting bacteria and activating scalp cutin, the active ingredients in the pseudolarix have the functions of dispelling wind, removing dampness, sterilizing and relieving itching, the sodium benzoate, the salicylic acid and the pseudolarix have synergistic effect when combined, are favorable for inhibiting and killing fungi parasitizing on the surface of hair and in hair follicles, have small irritation on hair follicles in the scalp, and have low toxic and side effects on human bodies.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present application and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained from the drawings without inventive effort.

Fig. 1 is a schematic flow chart illustrating a method for preparing a lotion for treating alopecia areata according to an embodiment of the present invention.

Detailed Description

To facilitate an understanding of the invention, the invention will now be described more fully with reference to the accompanying drawings. Preferred embodiments of the present invention are shown in the drawings. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.

It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only and do not represent the only embodiments.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

In one embodiment, a lotion for treating alopecia areata, comprising:

in this example, the sodium benzoate is a sodium salt of benzoic acid, and is also an acidic preservative, mostly white particles, no odor or slight benzoin odor, easy to dissolve in water, and astringent, in this example, 3 to 10 parts by mass of deionized water is used to dissolve the sodium benzoate. Sodium benzoate has no bactericidal and bacteriostatic effects in alkaline medium, has strong toxicity to microorganisms compared with benzoic acid, has small acute toxicity and is mild to scalp cells of human bodies, because the sodium benzoate has larger lipophilicity and is easy to penetrate through a phosphate bilayer to enter cell bodies, the permeability of cell membranes can be interfered, the absorption of amino acid by the cell membranes is inhibited, alkali storage in cells is ionized and acidified after entering the cell bodies, the activity of respiratory enzyme systems of the cells is inhibited, the condensation reaction of acetyl coenzyme A is prevented, the acetyl coenzyme A is an important intermediate metabolite of energy substance metabolism and is a pivotal substance in the metabolism of energy substances in vivo, three nutrient substances of sugar, fat and protein can generate acetyl coenzyme A in the metabolic process to enter tricarboxylic acid circulation, carbon dioxide and water are generated by oxidation, energy is released to synthesize ATP (Adenosine triphosphate, adenosine triphosphate) so as to cause the life activities of fungi to be dead due to lack of energy by inhibiting ATP synthesis, and further play a role in bacteriostasis and sterilization, wherein in a preferred mass fraction embodiment, the sodium benzoate is 8-10 parts.

In this example, the salicylic acid is a plant willow bark extract, is white needle-like or monoclinic crystal, is readily soluble in ethanol, is a natural anti-inflammatory agent, and is also a preservative. Salicylic acid can be used for removing cutin, killing bacteria, relieving inflammation, removing sweat odor, relieving itching, relieving swelling and pain. The salicylic acid and the sodium benzoate are mixed to enable the whole body of the liniment for treating alopecia areata to be weakly acidic, the sodium benzoate is partially hydrolyzed under an acidic condition to form benzoic acid, and the salicylic acid is used for dissolving hyperplastic scalp cutin to enable the sodium benzoate and the benzoic acid to better enter scalp hair follicles to deeply kill fungi at alopecia areata parts, wherein in a preferred mass fraction embodiment, the mass fraction of the salicylic acid is 8-14 parts.

In this example, the cortex pseudolaricis is the dry root bark or near root bark of the plant of pinus parviflora of Pinaceae, the organic acid in the cortex pseudolaricis has certain antibacterial effect on various pathogenic fungi, can cause the cell structure of the fungi to be denatured, cell organelles such as mitochondria and the like in cells to be dissolved, further causes cell membranes to be obviously shrunk and turn back into cytoplasm in a diverticulum shape, the active ingredients in the cortex pseudolaricis have the functions of dispelling wind and removing dampness, sterilizing and relieving itching, and the sodium benzoate and the salicylic acid are matched, so that the cortex pseudolaricis is beneficial to inhibiting and killing the fungi parasitized on the surface of the scalp and in the hair follicles, simultaneously can activate the cutin of the scalp, form a compact protective film, protect the cells of the scalp, prevent the reinfection of the fungi, and can relieve itching, pain and detumescence, is more comfortable when used by patients, and can relieve itching and pain, and the cortex pseudolaricis, the sodium benzoate and the salicylic acid have, in a preferred mass fraction embodiment, the mass fraction of the pseudolarix is 17 to 23 parts.

In this example, the ethanol is one of alcohols, which is a good solvent, and can be used to dissolve medicinal components in plants, meanwhile, 70% -75% of ethanol can be used for sterilization and disinfection, such as killing escherichia coli, staphylococcus aureus, candida albicans, pseudomonas aeruginosa, etc., lower concentration ethanol can also be used for reducing body temperature and promoting local blood circulation, the ethanol can be used to extract active ingredients in the hibiscus skin, i.e. organic acid, and improve the content of the active ingredients of the liniment for treating alopecia areata, in this example, 75% -80% of ethanol is used to soak the hibiscus skin, so that the volume fraction of ethanol in the alcohol extract of the hibiscus skin is not lower than 70%, and thus when the liniment for treating alopecia areata is used to paint affected parts, the ethanol can also primarily disinfect the surface of scalp, meanwhile, the ethanol is volatile, so that the temperature of the surface layer of the scalp of a patient can be reduced, the swelling can be relieved, and the comfort of the head of the patient can be improved at the affected part when the ointment is applied.

The invention provides a liniment for treating alopecia areata and a preparation method thereof, wherein sodium benzoate, salicylic acid and pseudolarix is used as main components, ethanol is used as an auxiliary aid to prepare the liniment for treating alopecia areata, the salicylic acid has the functions of inhibiting bacteria and dissolving cutin when used for treating alopecia areata, the whole liniment is weakly acidic, the benzoic acid is formed in the mixed liniment by the sodium benzoate, the salicylic acid and the liniment play the roles of inhibiting bacteria and activating scalp cutin, the active ingredients in the pseudolarix have the functions of dispelling wind, removing dampness, sterilizing and relieving itching, the sodium benzoate, the salicylic acid and the pseudolarix have synergistic effect when combined, are favorable for inhibiting and killing fungi parasitizing on the surface of hair and in hair follicles, have small irritation on hair follicles in the scalp, and have low toxic and side effects on human bodies.

In order to relieve the irritation of the paint for treating alopecia areata to human scalp, in one embodiment, the paint for treating alopecia areata further comprises 5-10 parts by mass of dendrobium officinale. Specifically, the dendrobium officinale has the effects of tonifying stomach, promoting fluid production, nourishing yin and clearing heat, and can treat symptoms such as fever body fluid damage, dry mouth, polydipsia, stomach yin deficiency, anorexia, retching, deficiency heat after illness, yin deficiency, fire excess, bone steaming, overstrain, dim eyesight, flaccidity of bones and muscles and bones and the like by an internal administration method. The paint for treating alopecia areata has certain irritation and corrosivity, and can cause certain damage to scalp cells when sterilizing the alopecia areata part. In the embodiment, the paint for treating alopecia areata is added with the dendrobium officinale component, when the paint is used for external application, scalp cell growth can be promoted, the dendrobium officinale contains a large amount of active polysaccharide, the active polysaccharide can activate dormant cells on the scalp, so that the cells can exert functions again, cell activity can be enhanced, the dendrobium officinale also contains a large amount of colloid and abundant vitamins, the vitamins have the effect of activating the walls of microvessels, absorption of nutrients in capillaries by hair follicles is facilitated, the colloid can supplement collagen required by scalp cells, can be directly absorbed by the scalp cells, and meanwhile irritation of sodium benzoate and salicylic acid to the scalp cells of people can be relieved. In addition, the dendrobium officinale contains abundant microelements such as iron and copper, which are important components of hair and can enhance the toughness of hair.

In order to further improve the bactericidal effect, in one embodiment, the paint for treating alopecia areata further comprises 5 to 15 parts by mass of citric acid. Specifically, citric acid is an organic acid, is a tricarboxylic acid compound, is colorless translucent crystals or white particles or white crystalline powder in appearance, has strong sour taste, and is easily soluble in water. The liniment for treating alopecia areata has the advantages that the citric acid component is added, the effect of well killing bacterial spores is achieved, so that the bacterial spores on the surface of a scalp and in hair follicles can be further killed by being matched with benzoic acid and salicylic acid, the sterilization effect is improved, the spores are dormant bodies of bacteria and can be converted into vegetative cells again under appropriate conditions, the stress resistance of the spores is strong, whether the spores can be killed or not is an important index for measuring the sterilization effect, and therefore the bacterial spores can be killed through the citric acid, and the alopecia areata can be effectively prevented from recurring. Furthermore, the citric acid can also accelerate the renewal of scalp cutin, the scalp cutin is activated by the scalp cutin and the pseudolarix which are dissolved and proliferated by the salicylic acid, and the citric acid, the pseudolarix and the salicylic acid supplement each other, so that the pores are promoted to remove redundant lipid, the blocking effect of scalp cells on external bacteria is improved, and the hair follicle is protected. Meanwhile, the hair-care mask can also thin the pores of the scalp, can better protect the hair follicles and can ensure that the alopecia areata part of a patient can grow hair again.

In order to further improve the bactericidal effect, in one embodiment, the paint for treating alopecia areata further comprises 5 to 8 parts by mass of selenium disulfide. Specifically, selenium disulfide can be used to remove the dandruff and eliminate the sebum and spill over, can clear away the sebum that sebaceous gland excreted, reduces fatty acid content in the sebum, and the effect molecule of other components of being convenient for directly contacts with the head affected part, does benefit to the fungi of sodium benzoate and salicylic acid direct action on the scalp, plays the effect of killing surface and the inside fungus of hair follicle, and citric acid can further kill the spore of bacterium. Meanwhile, the selenium disulfide can momentarily inhibit the growth of scalp epidermal cells, so that the epidermal cells are reduced alternately, the generation of cutin and dandruff is reduced, the active ingredients of the dendrobium officinale can enter hair follicles, and the buffer protection effect is achieved. In the cycle of treating alopecia areata, the composition can also play a role in killing bacterial spores together with citric acid, and further selenium in the selenium disulfide has the function of improving cellular immunity, can enhance the antifungal capacity of scalp cells, and has a better treatment effect.

In order to kill viruses on the surface of the scalp, in one embodiment, the liniment for treating alopecia areata further comprises 5 to 10 parts by mass of houttuynia cordata. Specifically, the houttuynia cordata contains houttuynin, volatile oil and quercitrin, the houttuynin is decanoyl acetaldehyde and has obvious inhibiting effect on beta coccus, bacillus influenzae, pneumococcus and staphylococcus aureus, the quercitrin has antiviral effect and can increase phagocytic capacity of white blood cells, promote tissue regeneration, expand capillary vessels and increase blood flow volume, so that nutrients can be better provided for hair shafts, the houttuynin and the volatile oil in the houttuynia cordata have inhibiting and antibacterial effects on various pathogenic bacilli, cocci, influenza viruses, leptospira and the like, so that the liniment for treating alopecia areata can kill fungi and viruses, so that the liniment for treating alopecia areata has better treatment effect, further, the houttuynia cordata is used together with cortex pseudolaricis and can effectively kill fungi and viruses, the property of the houttuynia cordata is slightly cold, the property of the dendrobium officinale is slightly cold, the pseudolarix has warm nature, mild drug effect when the pseudolarix, the pseudolarix and the pseudolarix are used in a matching way, low irritation to the scalp and good protection effect on the scalp.

In a comparative example, the liniment for treating alopecia areata, which is prepared from 5 to 12 parts by weight of sodium benzoate, 8 to 14 parts by weight of salicylic acid, 15 to 25 parts by weight of cortex pseudolaricis and 30 to 40 parts by weight of ethanol, is used for treating beriberi, and the active ingredients of the sodium benzoate, the salicylic acid and the cortex pseudolaricis have poor treatment effect on beriberi with pompholyx type and squamous keratosis type symptoms, and the beriberi is easy to relapse. Meanwhile, the foot cream has certain irritation to the skin, and is not suitable for erosive tinea pedis and secondary infection. Correspondingly, when the face cream is used for treating alopecia areata, the salicylic acid has the effects of inhibiting bacteria and dissolving cutin, the face cream is weak in acid overall, the face cream can jointly play the roles of inhibiting bacteria and activating scalp cutin by matching with the sodium benzoate, the active ingredients in the pseudolarix can effectively sterilize and relieve itching, and the sodium benzoate, the salicylic acid and the pseudolarix have the synergistic effect by matching and combining, so that the face cream is favorable for inhibiting and killing fungi parasitizing on the hair surface and in hair follicles.

In the comparative example, the paint for treating alopecia areata further comprises 5-10 parts by mass of dendrobium officinale, so that when the paint is used for treating beriberi, the treatment effect is poor, the situation of relapse is easy to occur, and the infection range is enlarged when the disease relapses. Correspondingly, when the traditional Chinese medicine composition is used for treating alopecia areata, the irritation of sodium benzoate and salicylic acid to scalp cells of a human body can be relieved while fungi parasitizing on the surface of hair and in hair follicles are effectively inhibited and killed, the cell activity can be enhanced, the scalp cells can play a role again, the capillary wall in the hair follicles can be activated, the absorption of the hair follicles to nutrients in capillaries is facilitated, collagen required by the scalp cells is supplemented, the effective sterilization effect is realized, the growth of the hair is promoted, further, the active ingredients in citric acid and houttuynia cordata are mutually cooperated when the alopecia areata is treated, the biological pathogenic factor of the induced alopecia areata can be killed by killing bacterial spores and viruses on the scalp cells, and the condition of alopecia areata recurrence can be prevented.

In order to improve the comfort when the paint for treating alopecia areata is applied, in one embodiment, the paint for treating alopecia areata further comprises 1-3 parts by mass of cysteine. Specifically, cysteine is an amino acid with physiological functions, has a sulfhydryl group with a reducing group, when inflammation or pruritus occurs on the surface of scalp, the activity of the thiozyme of the bile phospho-acetozyme can be reduced, and cysteine can maintain the activity of the thiozyme, so that the skin symptoms of inflammation or pruritus are improved, and the inflammation or pruritus symptoms of the head can be relieved after the liniment for treating alopecia areata is applied to a patient. Furthermore, when the cysteine is matched with dendrobium officinale, the activity of thiozyme can be maintained in the keratin generation of scalp surface cells, the normal metabolism of scalp cells can be maintained by supplementing the sulfur and active polysaccharide, so that the normal life activity of the cells in hair follicles can be maintained, the bottom melanin generated by pigment cells on the lowest layer of the epidermis can be regulated, and the hair grown from the hair follicles is healthy and glossy. Furthermore, after the liniment for treating alopecia areata is applied, the cuticle on the surface of the scalp can be dissolved to be contacted with epidermal cells for sterilization, so that the epidermal cells of the scalp are directly contacted with air, when foreign matters in the air are invaded after being contacted with the epidermal cells of the scalp, the self-defense capability of the epidermal cells of the skin can be enhanced, the defense mechanism of organisms can be adjusted, the invasion of external bacteria or viruses can be avoided, and a better treatment effect can be realized.

In one embodiment, a method for preparing a lotion for treating alopecia areata is provided. The preparation method of the paint for treating alopecia areata comprises the following steps:

step 110, the pseudolarix is ground into powder, then is added with ethanol for soaking, and is filtered to obtain the pseudolarix ethanol extract.

In the embodiment, the pseudolarix is put into a vertical grinder for grinding to obtain pseudolarix powder with the particle size of 50-75 um, 15-25 parts of the pseudolarix powder is weighed according to the formula proportion and put into a stirrer, 15-20 parts of ethanol is added, the mixture is stirred at the speed of 200-300 r/min for 3-5 min, the mixture is taken out and uniformly mixed, kept stand at room temperature for soaking for 24-60 hours, and finally filtered through a 300-mesh sieve to obtain a pseudolarix ethanol extract, and the pseudolarix ethanol extract is packaged and stored.

And step 120, dissolving sodium benzoate in deionized water to obtain a sodium benzoate solution.

In this embodiment, 5 to 12 parts of sodium benzoate is weighed according to the formula ratio, then sodium benzoate is added into a reaction vessel, and 3 to 10 parts of deionized water are added for blending until no sodium benzoate particles exist in the solution, that is, sodium benzoate is completely dissolved, so as to obtain a sodium benzoate solution, and the sodium benzoate solution is packaged and stored.

Step 130, dissolving salicylic acid in ethanol to obtain salicylic acid solution.

In this embodiment, 8 to 14 parts of salicylic acid is weighed according to a formula ratio, then 8 to 14 parts of salicylic acid and 15 to 20 parts of ethanol are added into a reaction vessel for blending until no salicylic acid particles exist in the solution, that is, the salicylic acid is completely dissolved in the ethanol to obtain a salicylic acid solution, and the salicylic acid solution is packaged and stored.

Step 140, uniformly mixing the alcohol extract of the pseudolarix, the sodium benzoate solution and the salicylic acid solution to obtain the paint for treating alopecia areata.

In the embodiment, the alcohol extract of pseudolarix, the sodium benzoate solution and the salicylic acid solution are added into a dispersion kettle, stirred at a stirring speed of 300-400 r/min for 3min, and then packaged for storage, so as to prepare the paint for treating alopecia areata.

A paint for treating alopecia areata as an external paint for treating alopecia areata as described in any one of the above embodiments. Specifically, the liniment for treating alopecia areata in the embodiment is an external medicine, and can be used for treating alopecia areata, wherein the alopecia areata is a local alopecia areata which is suddenly generated, the alopecia area is gradually enlarged along with gradual aggravation of the disease condition, and the image of a patient is adversely affected.

The invention is further described below with reference to specific examples.

Example 1

Putting the pseudolarix into a vertical grinder for grinding to obtain pseudolarix powder, weighing 15 parts of the pseudolarix powder according to the formula proportion, then adding 15 parts of ethanol for uniformly mixing, standing and soaking at room temperature, and finally filtering to obtain a pseudolarix alcohol extract; weighing 5 parts of sodium benzoate according to the formula proportion, adding 3 parts of deionized water, and mixing to obtain a sodium benzoate solution; weighing 8 parts of salicylic acid according to a formula ratio, and then adding 15 parts of ethanol for mixing to obtain a salicylic acid solution; adding the obtained alcohol extract of pseudolarix, sodium benzoate solution and salicylic acid solution into a dispersion kettle, stirring at a stirring speed of 300r/min for 3min, packaging, and storing to obtain the final product.

The paint for treating alopecia areata prepared by the embodiment has good antibacterial effect and skin pore activating effect, can inhibit and kill fungi parasitizing on the hair surface and in hair follicles when being used for treating alopecia areata, has small irritation to hair follicles in the scalp, and can effectively inhibit and treat alopecia areata of patients.

Example 2

Putting the pseudolarix into a vertical grinder for grinding to obtain pseudolarix powder, weighing 20 parts of the pseudolarix powder according to the formula proportion, then adding 17 parts of ethanol for uniformly mixing, standing and soaking at room temperature, and finally filtering to obtain a pseudolarix alcohol extract; grinding 5 parts by mass of dendrobium officinale and 5 parts by mass of houttuynia cordata into powder respectively, and adding the powder into the alcohol extract of pseudolarix; weighing 8 parts of sodium benzoate according to the formula proportion, adding 6 parts of deionized water, and mixing to obtain a sodium benzoate solution; weighing 11 parts of salicylic acid according to a formula ratio, and then adding 17 parts of ethanol for mixing to obtain a salicylic acid solution; adding the obtained alcohol extract of cortex pseudolaricis, sodium benzoate solution and salicylic acid solution into a dispersing kettle, stirring at a stirring speed of 350r/min for 3min, packaging, and storing to obtain the final product.

Compared with the example 1, the mass fraction of each component is increased, 5 parts of dendrobium officinale and 5 parts of houttuynia cordata are added, and the liniment for treating alopecia areata prepared in the example has a better effect of treating alopecia areata compared with the example 1, can activate dormant cells on scalp, enable the cells to exert functions again, enhance cell viability, activate microvascular walls, supplement collagen required by scalp cells, enhance toughness of hair, inhibit and resist various pathogenic bacilli, cocci, influenza viruses, leptospira and the like, can kill fungi and viruses, has mild drug effect during use, can relieve irritation to human scalp, has low irritation to scalp and has a good protective effect on scalp.

Example 3

Putting the pseudolarix into a vertical grinder for grinding to obtain pseudolarix powder, weighing 25 parts of the pseudolarix powder according to the formula proportion, then adding 20 parts of ethanol for uniformly mixing, standing and soaking at room temperature, and finally filtering to obtain a pseudolarix alcohol extract; grinding 10 parts by mass of dendrobium officinale and 10 parts by mass of houttuynia cordata into powder respectively, and adding the powder into the alcohol extract of pseudolarix; weighing 12 parts of sodium benzoate according to the formula proportion, adding 10 parts of deionized water, and mixing to obtain a sodium benzoate solution; adding 5 parts by mass of citric acid into a sodium benzoate solution; weighing 14 parts of salicylic acid according to a formula ratio, and then adding 20 parts of ethanol for mixing to obtain a salicylic acid solution; adding the obtained alcohol extract of pseudolarix, sodium benzoate solution and salicylic acid solution into a dispersing kettle, stirring at a stirring speed of 400r/min for 3min, packaging, and storing to obtain the final product.

Compared with the example 2, the paint for treating alopecia areata prepared in the example has better effect of treating alopecia areata, has good effect of killing bacterial spores and improves the bactericidal effect compared with the example 1, so that the paint for treating alopecia areata can be matched with benzoic acid and salicylic acid to further kill the bacterial spores on the surface of the scalp and in the hair follicle, effectively prevent the alopecia areata from recurring, accelerate the renewal of the scalp cutin, activate the scalp cutin through the scalp cutin and the pseudolarix which are dissolved and proliferated by the salicylic acid, and the citric acid, the pseudolarix and the salicylic acid supplement each other to promote pores to remove redundant lipids, improve the blocking effect of scalp cells on external bacteria and protect the hair follicles. Meanwhile, the hair-care mask can also thin the pores of the scalp, can better protect the hair follicles and can ensure that the alopecia areata part of a patient can grow hair again.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above embodiments only express a few embodiments of the present application, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the concept of the present application, which falls within the scope of protection of the present application. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. The liniment for treating alopecia areata is characterized by comprising the following components in parts by mass:

2. the varnish for treating alopecia areata as claimed in claim 1, further comprising: 3 to 10 parts by mass of deionized water.

3. The liniment for treating alopecia areata as claimed in claim 1, wherein the mass portion of the pseudolarix is 17-23.

4. The liniment for treating alopecia areata as claimed in claim 1, wherein the mass portion of the sodium benzoate is 8-10.

5. The liniment for treating alopecia areata as claimed in claim 1, wherein the salicylic acid is 8-14 parts by weight.

6. The liniment for treating alopecia areata according to claim 1, wherein the volume fraction of the ethanol is 75% to 80%.

7. A method for preparing a liniment for treating alopecia areata, which is characterized by comprising the following steps:

dissolving salicylic acid in ethanol to obtain a salicylic acid solution;

8. The liniment for treating alopecia areata as claimed in claim 7, wherein the hibiscus skin is pulverized, then soaked in ethanol, and filtered to obtain an alcohol extract of hibiscus skin comprising: