CN111954540A - 工程化靶标特异性核酸酶 - Google Patents

工程化靶标特异性核酸酶 Download PDF

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Publication number
CN111954540A
CN111954540A CN201980024453.9A CN201980024453A CN111954540A CN 111954540 A CN111954540 A CN 111954540A CN 201980024453 A CN201980024453 A CN 201980024453A CN 111954540 A CN111954540 A CN 111954540A
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sequence
zfn
subject
polynucleotide
cells
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Chinese (zh)
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R·德克尔弗
I·克里维加
J·C·米勒
张雷
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Sangamo Therapeutics Inc
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Sangamo Therapeutics Inc
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CN201980024453.9A 2018-02-08 2019-02-08 工程化靶标特异性核酸酶 Pending CN111954540A (zh)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201862628016P 2018-02-08 2018-02-08
US62/628,016 2018-02-08
US201862728226P 2018-09-07 2018-09-07
US62/728,226 2018-09-07
US201862758786P 2018-11-12 2018-11-12
US62/758,786 2018-11-12
US201962795937P 2019-01-23 2019-01-23
US62/795,937 2019-01-23
US201962802092P 2019-02-06 2019-02-06
US62/802,092 2019-02-06
PCT/US2019/017273 WO2019157324A1 (en) 2018-02-08 2019-02-08 Engineered target specific nucleases

Publications (1)

Publication Number Publication Date
CN111954540A true CN111954540A (zh) 2020-11-17

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CN201980024453.9A Pending CN111954540A (zh) 2018-02-08 2019-02-08 工程化靶标特异性核酸酶

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US (2) US11401512B2 (https=)
EP (1) EP3749350A4 (https=)
JP (2) JP7275152B2 (https=)
KR (1) KR20200118468A (https=)
CN (1) CN111954540A (https=)
AU (1) AU2019218118A1 (https=)
BR (1) BR112020015488A2 (https=)
CA (1) CA3089587A1 (https=)
IL (1) IL276490A (https=)
MX (1) MX2020008272A (https=)
RU (1) RU2020129448A (https=)
SG (1) SG11202007440YA (https=)
WO (1) WO2019157324A1 (https=)

Cited By (2)

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CN112805026A (zh) * 2019-02-06 2021-05-14 桑格摩生物治疗股份有限公司 用于治疗i型黏多糖贮积症的方法
CN112805375A (zh) * 2018-08-07 2021-05-14 桑格摩生物治疗股份有限公司 用于治疗ii型黏多糖贮积症的方法

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CA3066641A1 (en) * 2017-06-16 2018-12-20 Sangamo Therapeutics, Inc. Targeted disruption of t cell and/or hla receptors
US11512287B2 (en) * 2017-06-16 2022-11-29 Sangamo Therapeutics, Inc. Targeted disruption of T cell and/or HLA receptors
BR112021003399A2 (pt) 2018-08-24 2021-05-18 Spark Therapeutics, Inc. sequências de promotores otimizadas, construtos de expressão livres de íntron e métodos de uso
CN113423419A (zh) * 2019-01-04 2021-09-21 桑格摩生物治疗股份有限公司 用于治疗法布里病的方法和组合物
WO2021087361A1 (en) * 2019-11-01 2021-05-06 Sangamo Therapeutics, Inc. Zinc finger nuclease variants for treating or preventing lysosomal storage diseases
EP4165196A1 (en) * 2020-06-11 2023-04-19 Sangamo Therapeutics, Inc. Methods and compositions for expressing phenylalanine hydroxylase
JP2024515936A (ja) * 2021-03-19 2024-04-11 メタゲノミ，インク． Ｃａｓ酵素を用いたマルチプレックス編集
CN113293165B (zh) * 2021-06-21 2022-11-15 军事科学院军事医学研究院环境医学与作业医学研究所 一种基于CRISPR-Cas12a技术的HEV特异crRNA、检测试剂盒及其应用
US20230242922A1 (en) * 2021-09-13 2023-08-03 Life Technologies Corporation Gene editing tools

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