CN111760029A - Composition of medicinal prescription for treating tumor - Google Patents

Composition of medicinal prescription for treating tumor Download PDF

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CN111760029A
CN111760029A CN201910539998.5A CN201910539998A CN111760029A CN 111760029 A CN111760029 A CN 111760029A CN 201910539998 A CN201910539998 A CN 201910539998A CN 111760029 A CN111760029 A CN 111760029A
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赵新
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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Abstract

A composition of a medical prescription for treating tumor diseases, in particular to the technical field of medicines. The technical problem to be solved is as follows: good curative effect, good targeting property, fast treatment speed, less side effect, controllable state of illness, simple preparation, low cost and utilization of patent medicines and foods. The key points of the scheme are as follows: 1 part by weight of the fine powder of the water-flying cinnabar which is a sedative drug for calming the heart is used, 3 parts of the raw dry octopoda animal head hair meat paste is selected and added according to the specified characteristics, and the fresh amount is preferably 4 to 5 times of the dry amount according to the water content, and the two medicines are the monarch drugs together. The administration method comprises the following steps: it is swallowed slowly 3 times a day, and then taken with warm water or hot porridge, and the heart and liver meridians are taken frequently. The application is as follows: can be directly used as an oral patent medicine, can also be used for doctors to flexibly select ministerial medicines, adjuvant medicines and conductant medicines to prepare the oral patent medicine, is used for strengthening, suppressing the saint and shenwei, astringing the saint and wei, quickly treating tumor pain, reducing tumor and creating conditions for comprehensive treatment to eliminate tumor.

Description

Composition of medicinal prescription for treating tumor
Technical Field
The invention relates to the technical field of medicines, in particular to a composition of a medicinal prescription for treating tumor diseases.
Background
Tumors include malignant tumors and benign tumors, including lymphoid cancers. The incidence of malignant tumors is on the rise all over the world. Most malignant tumors are not recoverable and have high lethality rate. Seriously affecting human health, so the development of high-efficiency therapeutic drugs is urgent.
Modern medicine and modern traditional Chinese medicine consider that the etiology and pathogenesis of tumor generation are unclear. The reasons for the inability to cure the tumor are: the tumor is considered as a disease pathogen, only the body of the tumor is treated, and targeted excision or drug therapy is adopted, but global treatment is not carried out on the body of people except the tumor.
Tumors belong to endogenous diseases, called endogenous pathogenic factors, and most doctors consider the tumors to belong to psychological diseases. The modern medical treatment method is basically as follows: chemotherapy and radiation therapy. However, these treatments suffer from four major disadvantages: firstly, the treatment period is long, long-term medication is needed, and the treatment belongs to conservative treatment; secondly, only aiming at the tumor body, the treatment is not fundamental, the disease cannot be cured at all, the disease root cannot be cleared after improvement, and the disease mostly recurs. Thirdly, the side effects are strong, and the health of the human body is seriously damaged. Fourth, the drug is complex to prepare and expensive.
The invention relates to a composition of a pharmaceutical prescription for treating tumor diseases, which solves the fundamental problem. The method is characterized in that: the pathogenesis of the disease is determined, and the holy and shenwei, the Yuzi and the Shengying of the tumor patient are suppressed and converged to ensure that the diseases respectively enter the spirit, the wei, the shape and the ying. Has the advantages of rapid treatment, less side effects, fundamental treatment, low side effects, convenient preparation, controlled illness state, availability of patent medicine and food, and low cost. Meanwhile, the spirit and the ying-wei are not damaged.
The theoretical basis of the invention is as follows:
the overall therapeutic principle determines the etiology and pathogenesis of tumor, and the tumor is divided into yin and yang, and the yin and yang are: the division of the spirit caused by the division of the yang of the human body forms the spirit and the holy, and the holy is the yang of the tumor; human yang division leads to yin division, human yin division forms a shape and a residual shape, and the residual shape is a tumor; the tumor is yin. Wherein their respective spatial positions are: holy above the spirit; the tumor is above the shape. Because the sacrum is tied to the tumor, its survival and reproduction are more instinctive than the human body. Anodising the cathode, the tumour arises from the sacrum. The human spirit division causes the division of defensive qi of the human body to form defensive qi and shenwei qi; the division of human defensive qi leads to the division of human nutritive qi to form camp and sheng camp. Tumors are not pathogenic. Sheng and Sheng Wei are yang within yang; spirit and defense are yin of yang. Tumor and shengyying are yang within yin; the form and nutrient are the yin of the yin. The positive initiative and the negative initiative are quiet, the development and the survival of the tumor are determined by the holy and the saint defense, so the problem of incorrect treatment in the past is that: it is only used for treating residual body and tumor, but not for treating the root cause of diseases and the defense.
The book & Ying health Association is a whole article. The special emphasis is about the operation of the camp and the defense: ying is in the middle of the pulse, Wei is outside the pulse, Ying is not stopped, Wu Zao is large, and Yin and Yang are intersected, i.e. there is no end in the ring. Defensive qi flows in the twenty-five degrees of yin and in the twenty-five degrees of yang, and is divided into qi and blood deficiency of the aged … … in day and night, dry muscles, unsmooth airways, and less decline of ying qi and internal cutting of defensive qi due to poor essence of the day and no inferiority of the night. "Wei-defensive qi flows outside the vessels and Ying-nutritive qi flows inside the vessels. Saint wei is above wei. The pathogenic factors are caused by the rapid onset of disease, which is based on the transmission and development of five elements in the hour. The 1 cycle for transmission of the five zang organs was 28.8 minutes. The time to transfer 1 dirty is 5.76 minutes. It shows that the treatment of tumor should be synchronous with the speed of the disease, and the effect should be displayed within half an hour. The operation of the camp and the defense has five characteristics: dynamic, continuous, coordinated, periodic, and global. 5-7 Chen Shi and liver governing Shi; when noon is heart-dominant, heart governs fire and defensive qi enters heart meridian. At 3 pm, the lung governs gold and defensive qi enters lung meridian. 8 o' clock at night, when wood is present, liver governs wood, and nutritive qi is in liver meridian. At night, 11 o' clock, qi and blood are gathered in kidney meridian and deep sleep is achieved. The key points of the method for treating the neoplastic diseases are as follows: the medicine taking method is mastered according to the ying and defensive cycle, and the medicine is quickly treated, so that the sheng is suppressed and merged into the spirit; the saint guards are quickly compressed to incorporate them into the guards. At the same time, it can not hurt the spirit and ying-wei.
The aged 'dao de Jing' is absolutely saint and abandons the Min Zhi for a hundred times, absolutely kernel and abandons the Min Xiao Xiang Ci, absolutely desperate and abandons the Li and the thief does not have. "arrest tumor progression, yet another key is: the traditional Zheng method of TCM is used to suppress Sheng and Sheng Wei.
The traditional Chinese medicine considers that the heart governs the mind, and the holy part belongs to the mind beyond the heart, and the most common method for treating the mind beyond the heart by the traditional Chinese medicine is as follows: the sedative and tranquilizer is used as a monarch drug to calm the heart and tranquilize the mind by matching with the sedative and tranquilizer to regulate the five elements and astringe and tonify the qi of the zang-organs. The most common traditional method is Zhusha Anshen Wan. The treatment method related by the invention is as follows: the monarch drug must be introduced into the position of the yang, holy, in the middle of yang by using an introduction drug. It is not possible to directly suppress the heart spirit of yin in yang, otherwise the heart spirit is damaged, the tumor will rebound, and the disease condition is more serious. According to the traditional Chinese medicine, the first medicine for calming the heart and soothing the nerves is cinnabar, but cinnabar contains heavy metal mercury and is toxic. It is not usable for a long time. When it is used for a long time, it can be replaced by Magnetitum or other medicines with tranquilizing effect.
Characteristics specified for Octopus animals
The invention selects octopoda animals with the specified characteristics that: belongs to subclasses of cephalopoda animals without shells, and squid, octopus, cuttlefish, octopus and the like are available on the market. The method has the special capability that the intelligent large-scale active editing of the RNA chemical chain structure can reach 5 to 6 thousands of places during and after the RNA transcribes DNA, and a new protein is formed to adapt to the change of the environment. The manifestation of its ability is mostly concentrated on the head and hair parts. With the steepness of the change of the environment, the change of the edit quantity thereof takes an exponential growth form according to the steepness of the environment. Unlike humans and other animals on earth, humans can actively edit RAN, but only up to 40 to 50, other animals are comparable and non-exponential. The above is the characteristics specified for the octopoda subclasses of the present invention, and the selection is made according to the characteristics, and those without the characteristics are not selected.
Pharmacological properties of Octopus animals
The biological activity of the octopoda animal specified characteristics is expressed on the pharmacological properties of the traditional Chinese medicine: the external part is positive, and the internal part is negative; the properties of the medicine are convergent, mild, thick with thin in the middle, thin with thick in the middle, without inducing yang-clearing on the upper side, without disturbing ying yin on the lower side, with quiet in the middle and moving in the middle. Can be used as guiding drug to enter yang in yang, and astringe to drive yin in yang; it can also induce the herbs to enter yang in yin, and then enter yin through convergence. In addition, the theory of traditional Chinese medicine considers that octopoda animals have the functions of astringing and promoting granulation. The composition can be used in combination with tranquilizing and allaying excitement to suppress the development of tumor. Meanwhile, the purpose of protecting spirit and saint and wei is achieved. The aged says that: "Tian dao xi is complementary and deficient, ren dao is deficient and deficient", Octopus subclass animal pharmacological property is characteristic of Tian dao and can reverse, and neoplastic disease is paradoxical to ren dao.
Selecting fresh squid, octopus, cuttlefish and octopus which are easily purchased in the market, and selecting dry products for the second time. Protected species are not suitable. Cooked products cannot be selected, otherwise, the medicine is introduced into yin of yang, which damages the spirit.
The Laozi "Daodejing" states: the birth, moral animal, body shape, potential. The theory of Su Wen and Yin Yang corresponding elephant is: "Thick flavor will purge when it is thick, thin flavor will dredge when it is thin. "show that the thickness of the monarch drug and the guiding drug is dependent, the target is accurate and the drug is suitable for application.
The tumor belongs to endogenous diseases, the dosage of the channel inducing drugs different from exogenous diseases is less than that of main monarch drugs, and the traditional drugs are 0.5 times of that of the monarch drugs. Because the pathogenic factors are concentrated on 1 to 2 meridians, only 1 or 2 meridians are introduced. Endogenous diseases are caused by five internal organs, involve 12 meridians of all three yin and three yang meridians, are global diseases, and are introduced into 12 meridians, or upper and lower 6 yang meridians, or upper and lower 6 yin meridians as guiding drugs. Therefore, the dosage of the guiding drug is enlarged by 6 to 12 times compared with exogenous diseases. Fresh octopoda and octopoda animals are used as guiding drugs, and the weight of the fresh octopoda and octopoda animals is four to one fifth of that of the fresh octopoda animals after the fresh octopoda and octopoda animals are condensed into dry products. Therefore, the fresh product dosage is 30 times to 60 times of the traditional menses-inducing medicine according to the proportion. Thus, if the part of the introduced monarch drug is 1 weight unit, the dosage of the fresh octopoda animal and the fresh octopoda animal is 15 to 30 weight units.
Although the raw and fresh octopoda animals are guiding medicaments, the invention is regarded as monarch medicaments and guiding medicaments at the same time because the invention is characterized in that: the dosage of the invention is more than 3 times of the dosage of the introduced drug, and the invention has the function of convergence.
Disclosure of Invention
The invention relates to a composition of a pharmaceutical prescription for treating tumor diseases, which solves the global problem. The method is characterized in that: the etiology and pathogenesis of the disease are determined. And the patients with tumor are pressed and converged by the holy and shenwei, the Yun Yu Shi and the Shengying, so that the patients enter the spirit, the wei, the shape and the ying respectively. Has the advantages of high treatment speed, few side effects, fundamental treatment, low side effect, convenient preparation, disease condition control and low cost. Meanwhile, the spirit and the ying-wei are not damaged.
The technical problem to be solved by the invention is to overcome the defects of the prior art, and the 1 st technical problem to be solved by the invention is as follows: the traditional Chinese medicine composition solves the problems of good curative effect, high treatment speed, less side effect, capability of controlling the state of an illness, strengthened analgesia, low cost and convenient preparation. The composition of a medicinal prescription for treating tumor diseases is provided, 1 part by weight of fine powder of a medicine for calming the heart and soothing the nerves is used, 3 parts of raw dry octopoda animal head hair meat paste is selected and added according to specified characteristics, and according to the water content, the preferred fresh amount is 4 to 5 times of the dry amount, and the two medicines are monarch medicines together. The application is as follows: can be directly used as an oral patent medicine, can also be used for doctors to flexibly select ministerial medicines, adjuvant medicines and conductant medicines to prepare the oral patent medicine, is used for strengthening, suppressing the saint part and the saint part, astringing the saint part and the saint part, treating tumor pain, reducing tumor and creating conditions for comprehensive treatment to eliminate tumor.
The 2 nd technical problem to be solved by the invention is: according to the 1 st technical problem solving method, the composition of a medicinal prescription for treating the tumor disease is provided, and the taking method of the medicament when the medicinal prescription is taken as a monarch drug is characterized in that the medicinal prescription is placed in the mouth for fine chewing, is slowly swallowed after sublingual administration, and is taken with warm water or hot porridge after oral administration, wherein the taking time is that the heart and liver are taken mainly at any time. The application is as follows: can quickly and effectively inhibit tumor pain and treat tumor diseases.
The technical problem to be solved by the invention is realized by the following technical scheme:
a pharmaceutical formulation for treating tumor diseases is prepared by using 1 part by weight of fine powder of Cinnabaris (Cinnabaris) in the form of water extract for tranquilizing mind, selecting and adding 3 parts of meat paste of head and beard of Octopus animal according to specified characteristics, preferably 4-5 times of fresh product as dry product according to water content, and mixing the two medicines as principal medicines.
The medicine for treating tumor is taken through fine chewing in mouth, sublingual swallowing slowly and taking warm water or hot gruel for heart and liver.
The invention provides a composition of a pharmaceutical prescription for treating tumor diseases, which is prepared from two monarch drugs, and when in actual application, the mind-tranquilizing and nerve-soothing drugs can be widely selected from mineral drugs with the functions of relieving the mind and soothing the nerves, such as: magnetitum, dens Draconis, and Succinum. The drug can be used singly or in a mixed way, meanwhile, heavy metal mercury poisoning caused by long-term usage of cinnabar is avoided, and the proportioning dosage is executed according to the principle of the invention. The ministerial, adjuvant and conductant drugs can be added or subtracted according to the disease conditions of cold, heat, deficiency and excess. In practical application, the octopus ocellatus has the characteristics specified by the octopus ocellatus subclass animals, and can be sold under the tradenames of octopus ocellatus, cuttlefish, octopus and the like, and protected endangered animals are not selected.
The invention provides a composition of a pharmaceutical prescription for treating tumor diseases, which is prepared from two monarch drugs, wherein the heavy metal drugs are considered to be easy to injure the stomach in the practical application, and the adjuvant drugs, adjuvant drugs and conductant drugs are properly matched for assistance and alleviation. The auxiliary content can be considered to add astringent herbs such as roasted coptis root and roasted lotus plumule, which are capable of astringing, astringing and releasing heart and are kept stable when they cooperate with the sheng quilt to enter the spirit. For the alleviation, it is possible to add radix Glycyrrhizae Preparata and fructus Jujubae to protect the stomach from damage. Cautiously use febrile medicine to avoid the introduction of yang into yang, causing Shengwei 24915disease.
Results of pharmacological research
Shennong herbal is recorded, and cinnabar is the top grade herb for tranquilizing mind by nourishing the heart and tranquilizing the mind. It is widely used for treating sleep disorder caused by hyperactivity of heart fire and spirit, such as insomnia, mania, and pyocutaneous disease. The mercury-containing cinnabar compound is toxic and not suitable for long-term use, and can be replaced by magnetite or other sedative and tranquilizer after being used for a period of time. Sedative and tranquilizer are easy to injure stomach, and are actually used together with mild drugs and food.
The fresh octopodidae animals and the fresh octopodidae animals are used as guiding drugs, and the effects of relieving palpitation and soothing nerves are introduced into yang in yang, so that the injury to the spirit, the shape and the nutrient and defense are avoided.
The first broad category of efficacy achievement is characterized by:
the animal of Octopus and Octopus is used as guiding drug, the medicine for relieving mental stress is introduced into the Sheng, the Sheng Zhen is introduced into the Shen, the result is shown from the pulse condition, the original gushing pulse condition disappears, and the pulse promotion becomes gentle. And (3) displaying an electrocardiogram: the heart clutter disappears and the normal waveform is recovered. The cooked product can not be used, and the test shows that: instead, the drug is introduced into the yin of the yang.
The second broad category of efficacy achievement is characterized by:
the animals of Octopus and Octopus are used as guiding drugs, the tranquilizing drugs are introduced into the Shengwei, the Shengwei is introduced into the Weiwei, and the result is displayed from the pulse condition, and the original liver and spleen stringy pulse disappears. The original hook-shaped pulse disappears and the pulse condition is restored and relaxed. And (3) displaying an electrocardiogram: the heart clutter disappears and the normal waveform is recovered, and the physiological and pathological detection shows that the cardiac muscle action potential is recovered to be normal from low.
The third main category of efficacy achievement is characterized by:
the animals of Octopus and Octopus subclasses are used as guiding drugs, the tranquilizing drugs are introduced into Yuzi and Shengying, and the Yuzi and Shengying are introduced into Yuzi and Shengying. The pulse condition shows that the scattered pulse disappears, the original hook-shaped pulse disappears, and the pulse condition is restored and relaxed. And (3) displaying an electrocardiogram: the heart clutter disappears and the normal waveform is recovered, and the physiological and pathological detection shows that the cardiac muscle action potential is recovered to be normal from low.
The invention relates to a method for taking a medicine prepared from a pharmaceutical prescription for treating tumor diseases, which is characterized by comprising the following steps: is chewed finely in the mouth, swallowed slowly under the tongue, and then taken with warm water. The taking time is as follows: it is administered at 10 am and 8 pm, and is administered at heart and liver meridians. After the medicine is taken according to the method, the tumor pain can be inhibited within 28 minutes, and the purpose of quick treatment is achieved.
The method of taking the medicine requires slow swallowing because the effect of the medicine is exerted from the mouth, and the medicine passes through the tongue, the angina to the esophagus from the mouth and contacts with most of the meridians of the internal organs, especially the heart meridian and the pericardium meridian. The heart opens into the tongue, and the tongue is the place where the meridians pass under the tongue. Slow chewing, sublingual, and swallowing can allow the potency of the drug to act quickly and uniformly. If the medicine is taken directly with boiled water, the medicine effect and the speed can not be fully exerted. The medicinal efficacy can be diffused as soon as possible by drinking warm water. At 10 am, nutritive qi will be transmitted from the liver to the heart, and at this time, the medicine helps to astringe the heart spirit, the fire qi is astringing, wood cannot be burned, and the liver spirit is easy to astringe. If liver yang is hyperactivity and liver qi attacks the spleen in the weekdays, the medicine is taken at 3 pm in the morning, and Jinkemu has better effect than Zuojin pills. Take medicine and purge liver and gallbladder and astringe liver spirit when wood is at night 8. The medicine has the advantages of mild receiving and dispatching, high action speed, mind tranquilization, liver yang astringing, turbid qi rising prevention, prolonged and thick medicinal efficacy, lasting medicinal effect and appropriate decrement once the medicine is effective.
Advantageous effects
The comprehensive effects of the prescription provided by the invention are as follows: eliminating pain caused by tumor, inhibiting tumor development, and reducing and eliminating tumor.
Additional example 1: women in 66 years old, with good nationality, have gallbladder cancer diagnosed in 2017, pain, severe dryness, restlessness, splenic qi and adverse psychology. Morphine is adopted to relieve pain, and has serious side effect. Beginning in summer of 2018, the treatment method adopted by traditional Chinese medicine is as follows: 6g of cinnabar nerve-soothing pills and 18 g of fresh squid head hair, and the two medicines are fully stirred and mixed into emulsion which is taken as one day in 2 times a day. Pain is prevented and the patient feels the cancer substantially controlled, thereby relaxing the alertness without further combination therapy. Liver coma caused by sudden biliary tract blockage in the spring festival in 2019, emergency treatment is ineffective, and death is caused.
Additional example 2: female, 84 years old, original Beijing, national retired cadres, sudden epilepsy in spring, right arm spasm in 2019. And (4) detecting by nuclear magnetic resonance, and finding a meningioma below the top cranial plate, wherein the meningioma belongs to a benign tumor and has the size of 45 multiplied by 49 multiplied by 48 mm. After the disease, numbness of the right leg and the right arm occurs, the arm cannot be lifted, walking is difficult, the pulse is like a gushing heart pulse, the liver pulse is wiry, the spirit is often excited, the heartbeat is fast, and the patient is often irritated. In view of the fact that the patients are too old, the western medicine does not recommend surgical treatment, and the western medicine recommends anti-epileptic drugs to control the disease, but the anti-epileptic drugs have serious side effects and vomit after being taken. The treatment method adopted by the traditional Chinese medicine is as follows: purchased in a pharmacy, 6g of heart nourishing and mind tranquilizing pills containing magnetite and 18 g of minced meat of fresh squid head are fully stirred and mixed into emulsion which is taken as one day by 3 times a day. After half-month treatment, the hemp and wood of the right leg and the right arm are reduced, the right arm can be lifted and held normally basically, and the upper and lower 4-storey buildings do not need to be supported. Treatment is currently ongoing.
Contraindication of pharmacy and medicine taking
The pharmaceutical contraindication related by the invention is as follows: should not be combined with the herbs for tonifying yang and warming interior at the same time. The cooked product of the animals of Octopus and Octopus can not be used, and high temperature heating can not be performed before administration to ensure bioactivity.
The medication contraindication related to the invention is as follows: pregnant women, common cold, phlegm and fluid retention, damp-heat in liver channel, virus infection, bacterial infection, stagnation and distension, swelling and the like cannot be taken. It should be used with cautions for flaccidity of tendons. The drugs for tonifying yang, warming and dispersing wind-cold should not be taken at the same time.
Beneficial effects of pharmacological experiments
The experimental contents are as follows: the inhibition effect of the sculellaria barbata extract medicine on mouse liver cancer cells H22 is compared with that of the patent invention medicine. A
The experimental method comprises the following steps: establishing a mouse liver cancer tumor cell model, detecting the tumor cell inhibition capacity and the inactivation rate of the two medicaments by using a weighing and TUNEL marking method, and comparing the action effects of the two medicaments. As a result, the inhibition ability and the inactivation rate of the drug of the invention are better than those of the drug extracted from the sculellaria barbata.
Experimental materials:
animals and tumor strains, 40 Kunming mice, are divided into two groups, each group comprises 20 animals, each half of the animals is male and female, and the body mass is 17 to 22 g. Respectively called the sculellaria barbata group and the patent group. Ascites type mouse liver cancer H22 cell line.
The medicines, feed, drinking water, the crude extract and the fine extract of the barbed skullcap herb are the medicines which are generally accepted to have the anti-tumor capability. In the experiment, crude extract concentrated particles are adopted, the water content is 6%, the amount of mice fed with the crude extract every day is 1g, and 4 g of feed is added to form 5g of sculellaria barbata feed. 1 part of cinnabar and 3 parts of fresh living octopus body-removed meat paste are fully mixed, 1g of the amount of the feed for feeding a mouse every day is added with 4 g of the feed, and 5g of the patent feed is formed. The water is freely drunk.
Reagents and instruments, TUNEL kit, microsurgical kit, electronic balance, high speed refrigerated centrifuge.
The experimental method comprises the following steps:
inoculating and transplanting, namely inoculating a ascites type mouse liver cancer H22 cell line to an armpit of a mouse, and transplanting the cell line to liver lobes after anesthesia and surgery when tumors grow to 1cm after 6 days.
The feed is taken by the barbed skullcap herb group, 5g of barbed skullcap herb feed is fed every day, and water is freely drunk. The patent group is fed with 5g of patent feed every day and freely drinks water. The feed is fed for 15 days.
Compared with the effect of inhibiting tumors, mice are killed by a dislocation method, the tumors are stripped and weighed in a centralized way, the percentage of the weight of the tumors in the patent group to the weight of the tumors in the sculellaria barbata group is 50.9 percent, which is a comparative value after weighing, and the drug disclosed by the invention has stronger inhibition capability.
And (3) mouse tumor inactivation detection, wherein 12 samples are taken from each group, formaldehyde curing, paraffin embedding, section staining, TUNEL index detection, 400-time sampling microscopic observation, more than 1000 counted cells, inactivation index calculation and computer statistical analysis are adopted. The statistical result shows that the rate of the sculellaria barbata feed medicine is 19.63% +/-2.12, and the rate of the patent feed medicine is 29.11 +/-3.26.
The test result shows that the drug of the invention has stronger capability of inactivating tumor cells.
Detailed Description
Example 1, the composition and method of administration of a pharmaceutical formulation for the treatment of neoplastic diseases, preferably by: can be used for treating cancer pain, inhibiting tumor enlargement, and preventing digestive system diseases and discomfort. The traditional Chinese medicine is characterized by comprising the following traditional Chinese medicinal materials in parts by weight:
0.5g of water-refined cinnabar and 7.5g of minced meat prepared by removing the body of living squid are fully mixed, and the dosage is one day.
The medicine taking method comprises the following steps: the composition is administered two or three times a day. The administration time is 10-11 am, 4-5 pm, 8-9 pm, and the administration is carried out once respectively, and the medicated porridge is chewed finely, passed through sublingual, swallowed slowly, and taken after to protect gastric mucosa.
Example 2, the composition and method of administration of a pharmaceutical formulation for the treatment of neoplastic diseases, preferably by:
treating tumor of digestive tract system, gastrointestinal weakness, vague pain, Shengwei 24915disease, and excessive and rapid pulse of right cun guan chi. The traditional Chinese medicine is characterized by being prepared from the following traditional Chinese medicine and traditional Chinese medicinal materials in parts by weight:
0.3g of water-refined cinnabar, 1g of magnet, 12g of dens draconis calcined with vinegar and 15g of oyster calcined with vinegar, concentrated extract, 3g of honey-fried licorice root powder, 6g of Chinese date powder and 20 g of minced head beard and meat of living octopus. The above medicines are mixed with Chinese liquor to make into emulsion, which is 1 day for adult.
The taking method comprises the following steps: the medicine is taken at 10-11 am, 4-5 pm and 8-9 pm, and is chewed finely, passed through sublingual, swallowed slowly, and then taken with warm water.
Example 3 composition and method of administration of a pharmaceutical formulation for the treatment of neoplastic diseases, preferably by: the Chinese patent medicine cinnabar nerve-soothing pill is used for treating cancer pain and inhibiting tumor expansion, and is more suitable and convenient for home preparation.
The national pharmacopoeia legal cinnabar tranquilizing pill is a classic original prescription, 2 pills are large honeyed pills, 6g of each pill is used for 1 day for adults. The cinnabar contained in the drug is already 1 monarch drug.
The other 1 monarch drug is added: taking fresh cuttlefish, removing body, keeping the part above the neck, and mashing into fine meat paste with a mass of 36g being 3 times of that of big honeyed pill. Adding Chinese liquor as diluent and disinfectant, and mixing the two medicines to obtain emulsion.
The medicine taking method comprises the following steps: the composition is administered two or three times a day. The medicine is taken at 10-11 am, 4-5 pm and 8-9 pm, and is chewed finely, passed through sublingual, swallowed slowly, and then taken with warm water.

Claims (2)

1. A pharmaceutical formulation for treating tumor diseases is prepared by using 1 part by weight of fine powder of Cinnabaris (Cinnabaris) in the form of water extract for tranquilizing mind, selecting and adding 3 parts of meat paste of head and beard of Octopus animal according to specified characteristics, preferably 4-5 times of fresh product as dry product according to water content, and mixing the two medicines as principal medicines.
2. The composition of claim 1, wherein the pharmaceutical composition is administered orally in the form of fine chewing, sublingual, slow-swallowing, and then with warm water or hot porridge for the period of time that the heart and liver are administered at the time of administration.
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