CN111759913A

CN111759913A - Traditional Chinese medicine composition for treating intestinal bleeding and preparation method thereof

Info

Publication number: CN111759913A
Application number: CN202010800955.0A
Authority: CN
Inventors: 郑伟
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-08-10
Filing date: 2020-08-10
Publication date: 2020-10-13

Abstract

The invention discloses a traditional Chinese medicine composition for treating intestinal bleeding, which comprises the following raw materials: herba Hedyotidis Diffusae, fructus Sophorae, radix Sangusorbae, herba Taraxaci, flos Sophorae preparata, folium Platycladi preparata, herba Solani Lyrati, semen Trichosanthis, radix Linderae, and cortex Magnolia officinalis. The invention has the beneficial effects that: the traditional Chinese medicine composition for treating intestinal bleeding disclosed by the invention takes the sophora japonica charcoal and the cacumen biotae charcoal as main medicines and is matched with auxiliary medicines for detoxifying, regulating qi and cooling blood to stop bleeding, and the various raw materials supplement each other through reasonable proportioning, so that the traditional Chinese medicine composition has a good curative effect on intestinal bleeding caused by various reasons, particularly bleeding after haemorrhoids and rectal cancer operations, and can enable blood cells of intestinal bleeding patients to return to veins, improve the functions of sphincters, thereby effectively solving the troubles of the intestinal bleeding patients. The traditional Chinese medicine composition for treating intestinal bleeding is simple in preparation method and taking method, can be taken after being soaked in water, and has no toxic or side effect in the taking process.

Description

Traditional Chinese medicine composition for treating intestinal bleeding and preparation method thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating intestinal bleeding and a preparation method thereof.

Background

Hemorrhoid is one of common diseases and frequently encountered diseases in clinic, is a soft vein mass formed by expansion and buckling of submucosa at the tail end of anorectum and subcutaneous vein plexus of anal canal, is mainly clinically manifested by symptoms of hematochezia, pain, edema, falling swelling, pruritus, secretion increase, prolapse and the like, is easy to cause incarceration, necrosis, infection, gynecological inflammation, perianal eczema, vegetative nerve disorder and other systemic diseases, can cause anemia of different degrees after hematochezia for a long time, and even has hemorrhagic shock to endanger life; when the haemorrhoids are necrotic and seriously infected, the general infection can be caused by a blood system, the consequence is serious, the improper prevention and treatment can seriously affect the life, work, study and health of patients.

The census data indicate that the incidence of anorectal disease is 59.1%, with hemorrhoids accounting for 87.25% of all anorectal diseases, and internal hemorrhoids accounting for 52.19% of all anorectal diseases. The incidence rate of hemorrhoids in female patients is 67%, the incidence rate of hemorrhoids in male patients is 53.9%, the hemorrhoids are more common in 20-40 years old, and the hemorrhoids become more prevalent and gradually worse with the age.

Currently, treatment for hemorrhoids focuses on the elimination and relief of symptoms, and takes precedence over conservative treatment. Methods for treating hemorrhoids include surgical, oral and topical medications. The operative treatment comprises operations, ultra-low temperature treatment, ultra-high temperature treatment, injection treatment and the like, mainly aims at patients who are not cured for a long time or have formed large mixed hemorrhoids or annuloid hemorrhoids and has the defects of pain, easy generation of complications, incomplete treatment, easy relapse, high cost and the like. The oral medication and the external medication comprise oral or external western medicines or traditional Chinese medicines, and mainly relieve the pain of patients by softening excrement and reducing the impact of defecation on anus haemorrhoids, such as Mayilong musk haemorrhoids ointment and the like, but the existing oral medication and the external medication have the defects of slow effect, difficult focus elimination, incomplete treatment, easy relapse, low cure rate, unsatisfactory curative effect and the like. Therefore, the research on the hemorrhoid treatment medicine with definite curative effect, low recurrence rate and high patient compliance is urgently needed.

Disclosure of Invention

The invention aims to provide the traditional Chinese medicine composition for treating intestinal bleeding, which has the advantages of good curative effect, quick response, low cost and no toxic or side effect.

In order to achieve the purpose, the invention adopts the following technical scheme:

the invention provides a traditional Chinese medicine composition for treating intestinal bleeding, which comprises the following raw materials in parts by weight: 10-20 parts of oldenlandia diffusa, 15-25 parts of sophora fruit, 10-20 parts of garden burnet, 15-25 parts of dandelion, 10-20 parts of sophora flower charcoal, 10-20 parts of cacumen biotae charcoal, 10-15 parts of solanum lyratum, 15-20 parts of semen trichosanthis, 8-12 parts of radix linderae and 10-20 parts of mangnolia officinalis.

Preferably, the traditional Chinese medicine composition for treating intestinal bleeding comprises the following raw materials in parts by weight: 15 parts of spreading hedyotis herb, 20 parts of sophora fruit, 15 parts of garden burnet root, 20 parts of dandelion, 15 parts of sophora flower charcoal, 15 parts of cacumen biotae charcoal, 12 parts of solanum lyratum, 18 parts of semen trichosanthis, 10 parts of radix linderae and 15 parts of mangnolia officinalis.

The Chinese medicinal materials are bitter, sweet and cold, and have strong effects of removing toxicity and resolving carbuncle on carbuncle, swelling and sore throat, intestinal abscess and abdominal pain, venomous snake bite and other symptoms.

Fructus Sophorae, also called fructus Sophorae, semen Phaseoli vulgaris, and fructus Sophorae, is dry flower, flower bud, and mature fruit of Sophora japonica of Leguminosae, is cold in nature and bitter in taste, has effects of cooling blood, stopping bleeding, removing liver heat, and improving eyesight, and is often used for treating hemorrhoid hemorrhage, intestinal wind, hematochezia, metrorrhagia, blood stranguria, liver heat, conjunctival congestion, and dizziness.

Sanguisorba, also called radix astragali, fructus akebiae, fermented soybean or acid ochre, is bitter in taste and cold in nature, has the effects of stopping bleeding, cooling blood, clearing heat, removing toxicity, astringing to arrest diarrhea and inhibiting various pathogenic microorganisms and tumors, and is commonly used for treating hematemesis, bloody dysentery, burn, eczema, upper gastrointestinal hemorrhage, ulcer hemorrhage, hematochezia, metrorrhagia, tuberculous abscess, chronic osteomyelitis and other diseases.

Dandelion, also called herba crotalariae albidae, herba lysimachiae, herb of veronicae and Chinese flowering quince, belongs to perennial herb, is sweet and slightly bitter in taste, has the effects of diuresis, laxation, jaundice reduction, cholagogue and the like, and is often used for treating symptoms such as acute mastitis, lymphadenitis, scrofula, furunculosis, acute conjunctivitis, cold fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection and the like.

The sophora japonica charcoal is prepared by frying sophora japonica to carbon with strong fire, has stronger hemostatic effect compared with the sophora japonica, is mainly used for hemostasis, blood cooling and liver fire clearing, can remove intestinal toxicity and liver toxicity, and has the effect of protecting heart.

The cacumen biotae charcoal is prepared by processing folium Platycladi, and can better exert drug effect after processing. The traditional Chinese medicine considers that the components in the lateral bur leaves can treat alopecia caused by scalp atrophy, blood deficiency and blood heat alopecia. It also has therapeutic effect on alopecia areata and seborrheic alopecia. The cacumen biotae charcoal can stop bleeding, can obviously shorten bleeding time and blood coagulation time, and has the effects of cooling blood and stopping bleeding.

Solanum lyratum Thunb, neutral in nature and bitter in taste, has effects of clearing heat and promoting diuresis, removing toxic substance and subsiding swelling, and resisting cancer, and can be used for treating jaundice, edema, gonorrhea, cholecystitis, cholelithiasis, rheumarthritis, etc.

Semen Trichosanthis is dry seed of Trichosanthes kirilowii Maxim of Trichosanthes of Cucurbitaceae, has effects of clearing lung-heat, eliminating phlegm, and smoothing intestine and relaxing bowels, and can be used for treating phlegm-heat cough, lung deficiency dry cough, intestinal dryness constipation, etc.

The radix Linderae is dry root tuber of radix Linderae of Lauraceae, has effects of activating qi-flowing, relieving pain, warming kidney and dispelling cold, and can be used for treating cold coagulation and qi stagnation, chest and abdomen pain, adverse qi, dyspnea with rapid respiration, bladder deficiency cold, enuresis, frequent micturition, hernia pain, cold channel, and abdominal pain.

The magnolia officinalis can relieve incoordination between the spleen and the stomach caused by food retention and qi stagnation to a great extent, has a good curative effect on abdominal distension, can inhibit secretion of gastric juice, has a prevention and treatment effect on gastric ulcer, and has a good inhibition effect on pneumococcus and a plurality of dermatophytes.

Preferably, the traditional Chinese medicine composition for treating intestinal bleeding also comprises the following raw materials, by weight, 15-20 parts of barbed skullcap herb, 12-18 parts of black nightshade herb, 12-15 parts of sargentgloryvine stem, 15-20 parts of dahurian patrinia herb and 12-18 parts of honeysuckle stem.

Preferably, the traditional Chinese medicine composition comprises the following raw materials, by weight, 15 parts of spreading hedyotis herb, 20 parts of sophora fruit, 15 parts of garden burnet root, 20 parts of dandelion, 15 parts of sophora flower charcoal, 15 parts of cacumen biotae charcoal, 12 parts of solanum lyratum thunb, 18 parts of snakegourd seed, 10 parts of combined spicebush root, 15 parts of mangnolia officinalis, 18 parts of sculellaria barbata, 15 parts of black nightshade herb, 13 parts of sargentgloryvine stem, 18 parts of dahurian patrinia herb and 15 parts of honeysuckle stem.

Scutellaria barbata, Portulacaceae, annual herbaceous plant, has effects of cooling blood, removing toxic substance, relieving swelling, clearing heat and promoting diuresis.

The black nightshade is bitter in taste and cold in nature, and has the effects of clearing heat, detoxifying, activating blood and reducing swelling. It is often used to treat furuncle, carbuncle, erysipelas, traumatic injury, chronic cough, asthma with phlegm, edema, and cancer.

Sargentgloryvine stem, also called as sargentgloryvine stem, has the effects of clearing and activating the channels and collaterals, dissipating blood stasis and relieving pain, regulating qi and promoting blood circulation, killing parasites and the like, and is usually used for treating symptoms such as rheumatalgia, joint soreness, traumatic injury, dysmenorrheal, amenorrhea and the like caused by weather change.

Patrinia, a whole plant with roots of Patrinia scabiosaefolia (L.) Pat. or Patrinia villosa (L.) Pat. No. Patrinia villosa) of Patrinia, is a wild plant resource with high development and utilization values and medicinal values. Has the effects of clearing away heat and toxic materials, cooling blood, removing blood stasis, relieving pain, eliminating carbuncle, removing toxic materials, etc., and can be used for treating hyperpyrexia, cough with purulent blood, chest and abdominal pain, appendicitis, enteritis, dysentery, puerperal abdominal pain, dysmenorrhea, etc.

The honeysuckle stem, also known as Ficus pumila, salix chinensis and stephania japonica, has the curative effects of clearing heat and removing toxicity, and dispelling wind and dredging collaterals. It is commonly used to treat febrile disease, sore, carbuncle, toxic swelling, dysentery with bloody stool, arthralgia due to wind-damp-heat, and red swelling and pain of joint.

Preferably, the intestinal bleeding is intestinal bleeding caused by hemorrhoids and intestinal bleeding caused by rectal cancer surgery.

The traditional Chinese medicine composition for treating intestinal hemorrhage disclosed by the invention is applied to the aspect of treating haemorrhoid hemorrhage.

The traditional Chinese medicine composition for treating intestinal hemorrhage can be used for treating haemorrhoid hemorrhage, and the traditional Chinese medicine composition for treating intestinal hemorrhage adopts the following formula: 10-20 parts of oldenlandia diffusa, 15-25 parts of sophora fruit, 10-20 parts of garden burnet, 15-25 parts of dandelion, 10-20 parts of sophora flower charcoal, 10-20 parts of cacumen biotae charcoal, 10-15 parts of solanum lyratum, 15-20 parts of semen trichosanthis, 8-12 parts of radix linderae and 10-20 parts of mangnolia officinalis, and the medicine has better curative effect on haemorrhoids bleeding.

The traditional Chinese medicine composition for treating intestinal bleeding disclosed by the invention is applied to the aspect of treating intestinal bleeding caused by rectal cancer surgery.

The traditional Chinese medicine composition for treating intestinal bleeding can be used for treating intestinal bleeding caused by rectal cancer surgery, and the traditional Chinese medicine composition for treating intestinal bleeding adopts the following formula: 10-20 parts of oldenlandia diffusa, 15-25 parts of sophora fruit, 10-20 parts of garden burnet, 15-25 parts of dandelion, 10-20 parts of sophora flower charcoal, 10-20 parts of cacumen biotae charcoal, 10-15 parts of solanum lyratum, 15-20 parts of semen trichosanthis, 8-12 parts of combined spicebush root, 10-20 parts of mangnolia officinalis, 15-20 parts of sculellaria barbata, 12-18 parts of black nightshade, 12-15 parts of sargentgloryvine stem, 15-20 parts of herba patriniae and 12-18 parts of honeysuckle stem, and has better effect on treating intestinal bleeding caused by rectal cancer surgery.

The preparation method of the traditional Chinese medicine composition for treating intestinal bleeding comprises the following steps: drying the raw materials, uniformly mixing the dried raw materials, and sterilizing to obtain the traditional Chinese medicine composition for treating intestinal bleeding.

Preferably, the drying temperature is 60-80 ℃, and preferably, the raw materials are dried to the water content of 6-8 wt%. The raw materials are dried, so that the raw materials are convenient to store.

Preferably, the sterilization is microwave sterilization. The microwave sterilization is to make the microorganism in the raw material simultaneously receive the combined action of microwave thermal effect and non-thermal effect, so that the variation of protein and physiological active substance in the body of the microorganism is generated, thereby causing the growth and development of the microorganism to be delayed and dead, and achieving the purposes of sterilizing and preserving the raw material.

Compared with the prior art, the invention has the beneficial effects that:

the traditional Chinese medicine composition for treating intestinal bleeding disclosed by the invention takes the sophora japonica charcoal and the cacumen biotae charcoal as main medicines and is matched with auxiliary medicines for detoxifying, regulating qi and cooling blood to stop bleeding, and the various raw materials supplement each other through reasonable proportioning, so that the traditional Chinese medicine composition has a good curative effect on intestinal bleeding caused by various reasons, particularly bleeding after haemorrhoids and rectal cancer operations, and can enable blood cells of intestinal bleeding patients to return to veins, improve the functions of sphincters, thereby effectively solving the troubles of the intestinal bleeding patients.

The traditional Chinese medicine composition for treating intestinal bleeding is simple in preparation method and taking method, can be taken after being soaked in water, and has no toxic or side effect in the taking process.

Detailed Description

In order to better understand the essence of the present invention, the following detailed description is made with reference to the examples, which are not intended to limit the present invention, but are merely illustrative, and modifications, substitutions or improvements can be made without departing from the spirit and principle of the present invention.

The use method of the traditional Chinese medicine composition for treating intestinal bleeding provided by the invention comprises the following steps: soaking the composition in boiling water for 5-10 min, and drinking the soaking water. 3 weeks is a treatment course, and the soaking water is taken twice a day in the first week and once a day from the second week.

In the examples of the present application, 1 part by weight represents 1 g.

Example 1

The embodiment provides a traditional Chinese medicine composition for treating intestinal bleeding, which comprises the following raw materials, by weight, 10 parts of oldenlandia diffusa, 15 parts of sophora fruit, 10 parts of garden burnet, 15 parts of dandelion, 10 parts of sophora flower charcoal, 10 parts of cacumen biotae charcoal, 10 parts of solanum dulcamara, 15 parts of semen trichosanthis, 8 parts of radix linderae, and 10 parts of mangnolia officinalis. The preparation method comprises the following steps: drying the raw materials at a drying temperature of 60 ℃ until the water content of the raw materials is 6 wt%, uniformly mixing the dried raw materials, and performing microwave sterilization to obtain the traditional Chinese medicine composition for treating intestinal bleeding.

Example 2

The embodiment provides a traditional Chinese medicine composition for treating intestinal bleeding, which comprises the following raw materials, by weight, 15 parts of oldenlandia diffusa, 20 parts of sophora fruit, 15 parts of garden burnet, 20 parts of dandelion, 15 parts of sophora flower charcoal, 15 parts of cacumen biotae charcoal, 12 parts of solanum dulcamara, 18 parts of semen trichosanthis, 10 parts of radix linderae and 15 parts of mangnolia officinalis. The preparation method comprises the following steps: drying the raw materials at the drying temperature of 70 ℃ until the water content of the raw materials is 7 wt%, uniformly mixing the dried raw materials, and performing microwave sterilization to obtain the traditional Chinese medicine composition for treating intestinal bleeding.

Example 3

The embodiment provides a traditional Chinese medicine composition for treating intestinal bleeding, which comprises the following raw materials, by weight, 20 parts of oldenlandia diffusa, 25 parts of sophora fruit, 20 parts of garden burnet, 25 parts of dandelion, 20 parts of sophora flower charcoal, 20 parts of cacumen biotae charcoal, 15 parts of solanum dulcamara, 20 parts of semen trichosanthis, 12 parts of radix linderae and 20 parts of mangnolia officinalis. The preparation method comprises the following steps: drying the raw materials at the drying temperature of 80 ℃ until the water content of the raw materials is 8 wt%, uniformly mixing the dried raw materials, and performing microwave sterilization to obtain the traditional Chinese medicine composition for treating intestinal bleeding.

Example 4

The embodiment provides a traditional Chinese medicine composition for treating intestinal bleeding, which comprises the following raw materials, by weight, 10 parts of oldenlandia diffusa, 15 parts of sophora fruit, 10 parts of garden burnet, 15 parts of dandelion, 10 parts of sophora flower charcoal, 10 parts of cacumen biotae charcoal, 10 parts of solanum dulcamara, 15 parts of semen trichosanthis, 8 parts of radix linderae, 10 parts of mangnolia officinalis, 15 parts of sculellaria barbata, 12 parts of black nightshade, 12 parts of sargentgloryvine stem, 15 parts of herba patriniae, and 12 parts of honeysuckle stem. The preparation method comprises the following steps: drying the raw materials at a drying temperature of 60 ℃ until the water content of the raw materials is 6 wt%, uniformly mixing the dried raw materials, and performing microwave sterilization to obtain the traditional Chinese medicine composition for treating intestinal bleeding.

Example 5

The embodiment provides a traditional Chinese medicine composition for treating intestinal bleeding, which comprises the following raw materials, by weight, 15 parts of oldenlandia diffusa, 20 parts of sophora fruit, 15 parts of garden burnet, 20 parts of dandelion, 15 parts of sophora flower charcoal, 15 parts of cacumen biotae charcoal, 12 parts of solanum dulcamara, 18 parts of semen trichosanthis, 10 parts of radix linderae, 15 parts of mangnolia officinalis, 18 parts of sculellaria barbata, 15 parts of black nightshade, 13 parts of sargentgloryvine stem, 16 parts of herba patriniae, and 15 parts of honeysuckle stem. The preparation method comprises the following steps: drying the raw materials at the drying temperature of 70 ℃ until the water content of the raw materials is 7 wt%, uniformly mixing the dried raw materials, and performing microwave sterilization to obtain the traditional Chinese medicine composition for treating intestinal bleeding.

Example 6

The embodiment provides a traditional Chinese medicine composition for treating intestinal bleeding, which comprises the following raw materials, by weight, 20 parts of oldenlandia diffusa, 25 parts of sophora fruit, 20 parts of garden burnet, 25 parts of dandelion, 20 parts of sophora flower charcoal, 20 parts of cacumen biotae charcoal, 15 parts of solanum dulcamara, 20 parts of semen trichosanthis, 12 parts of radix linderae, 20 parts of mangnolia officinalis, 20 parts of sculellaria barbata, 18 parts of black nightshade, 15 parts of sargentgloryvine stem, 20 parts of herba patriniae, and 18 parts of honeysuckle stem. The preparation method comprises the following steps: drying the raw materials at the drying temperature of 80 ℃ until the water content of the raw materials is 8 wt%, uniformly mixing the dried raw materials, and performing microwave sterilization to obtain the traditional Chinese medicine composition for treating intestinal bleeding.

Comparative example 1

This comparative example differs from example 3 in that: does not contain the raw material of the sophora flower charcoal.

Comparative example 2

This comparative example differs from example 3 in that: does not contain the raw material of cacumen biotae carbon.

Comparative example 3

This comparative example differs from example 3 in that: comparative example 3 contains 35 parts by weight of cacumen Platycladi carbon.

Comparative example 4

This comparative example differs from example 6 in that: does not contain the raw material of black nightshade.

Comparative example 5

This comparative example differs from example 6 in that: does not contain the raw material sargentgloryvine stem.

Comparative example 6

This comparative example differs from example 6 in that: does not contain raw material honeysuckle stem.

1. The effect research of the traditional Chinese medicine composition for treating intestinal bleeding (hemorrhoidal bleeding)

The hemorrhoid diagnosis method comprises the steps of selecting 80 cases of outpatient medical records with the ages of 20-50 according to hemorrhoid diagnosis in Chinese medicine industry standard of Chinese medicine and anorectal disease diagnosis curative effect standard of China, which is formulated by the national traditional Chinese medicine administration of 1994, and randomly and averagely dividing the cases into 8 groups, a test group 1-4 groups and a control group 1-4 groups.

The treatment method comprises the following steps: test groups 1 to 4 were administered water infused with the herbal compositions for intestinal bleeding prepared in examples 1 to 3 and 6, respectively; the control groups 1-3 respectively drink water infused with the traditional Chinese medicine composition for treating intestinal bleeding prepared in the comparative examples 1-3, and the weight ratio of the traditional Chinese medicine composition to the water is 1: 5, soaking for 10 minutes in boiled water, taking three weeks as a treatment course, drinking the soaking water twice a day in the first week, 250mL each time, and drinking the soaking water once a day from the second week, 250mL each time; in the control group 4, HUAZHI pill is orally administered at a dose of 3 g/time and 2 times/day.

Observing haemorrhoids hemorrhage at 7, 15 and 21 days after administration, and removing haemorrhoids (score 0) according to 3-point method (4 level); mild bulging of hemorrhoids with no bleeding (1 point); moderate bulge of hemorrhoid and contact hemorrhage

(2 min); haemorrhoids were severely elevated, jet bleeding (3 points), scored and compared (n ═ 10, X ± S), and the results are shown in table 1:

TABLE 1 haemorrhoids bleeding status of each group

	7 th day after administration	Day 15 after administration	Day 21 after administration
				Test group 1	1.51±1.297^*	0.35±1.363^**	0.07±1.005^**
Test group 2	1.50±1.362^*	0.40±1.289^**	0.08±1.011^**
				Test group 3	1.49±1.496^*	0.38±1.358^**	0.07±1.003^**
Test group 4	1.71±1.291^*	0.58±1.212^**	0.13±1.005^**
				Control group 1	2.01±1.253	1.23±1.218	0.79±1.008
Control group 2	1.98±1.258	1.36±1.223	0.80±1.011
				Control group 3	1.93±1.289	1.27±1.311	0.78±1.013
Control group 4	2.23±1.241	1.41±1.305	0.81±1.026

Compared with the control group 4, the ratio of the active ingredients,^*P<0.05，^**P<0.01。

as can be seen from table 1, compared with the control group 4, the scores of the test groups have significant differences, which shows that the traditional Chinese medicine composition for treating intestinal hemorrhage has a good curative effect on hemorrhoid hemorrhage, and has obvious advantages compared with the commercially available products, and the test groups 1-3 are superior to the test group 4, namely when the formula of the composition is oldenlandia diffusa, sophora fruit, sanguisorba officinalis, dandelion, sophora japonica charcoal, cacumen biotae charcoal, solanum dulcamara, semen trichosanthis, lindera aggregata, and magnolia officinalis, the treatment effect on hemorrhoid is better;

from the comparison between the test groups 1-3 and the control groups 1-3, it can be known that when part of the raw material components or parts by weight in the composition of the present invention are changed, the treatment effect is significantly reduced, which indicates that the various raw materials in the Chinese medicinal composition for treating intestinal bleeding of the present invention cooperate with each other to obtain a better treatment effect.

2. The effect research of the traditional Chinese medicine composition for treating intestinal bleeding (intestinal bleeding caused by rectal cancer operation) provided by the invention

70 patients with post-operation hemafecia of rectal cancer, age 40-60 years, were randomly and averagely divided into 7 groups, test group 1-4 groups, and control group 1-3 groups.

The treatment method comprises the following steps: the test groups 1 to 4 were administered with water infused with the herbal compositions for intestinal bleeding prepared in examples 3 and 4 to 6, respectively, and the control groups 1 to 3 were administered with water infused with the herbal compositions for intestinal bleeding prepared in comparative examples 4 to 6, respectively, wherein the herbal compositions were water 1: 5, soaking for 10 minutes in boiled water, taking three weeks as a treatment course, drinking the soaking water twice a day in the first week, 250mL each time, and drinking the soaking water once a day from the second week, 250mL each time.

Observing the symptoms of a patient with rectal cancer postoperative hematochezia after taking the medicine for one course of treatment, wherein the evaluation standard of the curative effect is as follows: the bellyache and the hematochezia are respectively or completely relieved and disappeared to be effective, and otherwise, the bellyache and the hematochezia are ineffective; the results are shown in table 2:

and (3) healing: the symptoms of abdominal pain and hematochezia disappear; the method has the following advantages: the abdominal pain symptom disappears, and the hematochezia symptom is relieved; and (4) invalidation: the symptoms of abdominal pain and hematochezia are not obviously improved.

TABLE 2 post-operative hematochezia status of various groups of rectal carcinomas

	The number of healed people	Number of effective persons	Number of invalid persons
				Test group 1	6	4	0
Test group 2	8	2	0
				Test group 3	8	2	0
Test group 4	9	1	0
				Control group 1	5	4	1
Control group 2	4	4	2
				Control group 3	5	4	1

As can be seen from table 2, the traditional Chinese medicine composition for treating intestinal bleeding has a good effect of treating hemafecia after rectal cancer surgery, and when the formula of the traditional Chinese medicine composition for treating intestinal bleeding is oldenlandia diffusa, sophora fruit, sanguisorba officinalis, dandelion, sophora japonica charcoal, cacumen biotae charcoal, solanum dulcamara, semen trichosanthis, lindera aggregata, magnolia officinalis, scutellaria barbata, solanum nigrum, sargentgloryvine stem, patrinia scandens and honeysuckle stem, the treatment effect on the hemorrhage after rectal cancer surgery is better;

as can be seen from the comparison between the test groups 4-6 and the control groups 1-3, the traditional Chinese medicine composition for treating intestinal bleeding has better treatment effect due to the mutual matching of various raw materials.

The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.

Claims

1. A traditional Chinese medicine composition for treating intestinal bleeding is characterized by comprising the following raw materials in parts by weight: 10-20 parts of oldenlandia diffusa, 15-25 parts of sophora fruit, 10-20 parts of garden burnet, 15-25 parts of dandelion, 10-20 parts of sophora flower charcoal, 10-20 parts of cacumen biotae charcoal, 10-15 parts of solanum lyratum, 15-20 parts of semen trichosanthis, 8-12 parts of radix linderae and 10-20 parts of mangnolia officinalis.

2. The traditional Chinese medicine composition for treating intestinal bleeding according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 15 parts of spreading hedyotis herb, 20 parts of sophora fruit, 15 parts of garden burnet root, 20 parts of dandelion, 15 parts of sophora flower charcoal, 15 parts of cacumen biotae charcoal, 12 parts of solanum lyratum, 18 parts of semen trichosanthis, 10 parts of radix linderae and 15 parts of mangnolia officinalis.

3. The traditional Chinese medicine composition for treating intestinal bleeding according to claim 1, further comprising raw materials of, by weight, 15-20 parts of barbed skullcap herb, 12-18 parts of black nightshade herb, 12-15 parts of sargentgloryvine stem, 15-20 parts of dahurian patrinia herb and 12-18 parts of honeysuckle stem.

4. The traditional Chinese medicine composition for treating intestinal bleeding according to claim 3, which is prepared from 15 parts by weight of oldenlandia diffusa, 20 parts by weight of sophora fruit, 15 parts by weight of sanguisorba officinalis, 20 parts by weight of dandelion, 15 parts by weight of sophora flower charcoal, 15 parts by weight of cacumen biotae charcoal, 12 parts by weight of solanum lyratum thunb, 18 parts by weight of semen trichosanthis, 10 parts by weight of radix linderae, 15 parts by weight of magnolia officinalis, 18 parts by weight of herba scutellariae barbatae, 15 parts by weight of black nightshade, 13 parts by weight of sargentgloryvine stem, 18 parts by weight.

5. The Chinese medicinal composition for treating intestinal bleeding according to any one of claims 1 to 4, wherein the intestinal bleeding is intestinal bleeding caused by hemorrhoids and intestinal bleeding caused by rectal cancer surgery.

6. The use of the composition of claim 1 for the treatment of bleeding from hemorrhoids.

7. The use of the composition of claim 3 for the treatment of intestinal bleeding caused by rectal cancer surgery.

8. The method for preparing a Chinese medicinal composition for treating intestinal hemorrhage according to any one of claims 1 to 4, wherein the Chinese medicinal composition for treating intestinal hemorrhage is obtained by drying the raw materials, uniformly mixing the dried raw materials and sterilizing.

9. The preparation method of the traditional Chinese medicine composition for treating intestinal bleeding according to claim 8, wherein the drying temperature is 60-80 ℃, and preferably, the raw materials are dried until the water content is 6-8 wt%.

10. The method for preparing a Chinese medicinal composition for treating intestinal hemorrhage according to claim 8, wherein the sterilization is microwave sterilization.