CN113499407A - Traditional Chinese medicine mixture for treating helicobacter pylori and preparation method thereof - Google Patents
Traditional Chinese medicine mixture for treating helicobacter pylori and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine mixture for treating helicobacter pylori and a preparation method thereof, wherein the mixture is prepared from the following raw material medicines in parts by weight: 15 of radix scutellariae, 8 of rheum officinale, 30 of hedyotis diffusa, 10 of coptis chinensis, 30 of dandelion, 30 of sweet wormwood, 10 of caulis perllae, 10 of costustoot, 3 of pseudo-ginseng powder, 15 of cardamom, 15 of eupatorium, 10 of white peony root, 6 of raw liquorice, 10 of bamboo leaves and 15 of coix seeds. The pharmaceutical composition has stronger inhibiting and killing effects on helicobacter pylori, has higher curative effect on helicobacter pylori infection, has no adverse reaction and toxic or side effect after long-term administration, and reduces the treatment cost by more than 60 percent compared with the current western medicines for treating the disease.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine mixture for treating helicobacter pylori and a preparation method thereof.
Background
Symptoms of helicobacter pylori infection: (1) mainly sour regurgitation, heartburn, stomachache and halitosis. The main reason is that helicobacter pylori induces crazy secretion of gastrin to generate acid and burn hearts, and helicobacter pylori causes stomachache which is the main symptom of patients with gastric ulcer diseases, and one of the most direct bacteria of halitosis is helicobacter pylori. (2) Helicobacter pylori can cause chronic gastritis. The main clinical manifestations that occur are: discomfort and dull pain in the upper abdomen may cause symptoms of belching, acid regurgitation, nausea and vomiting, and the disease course is slow, but the disease is easy to recur. (3) After a patient is infected with helicobacter pylori, various pathogenic factors are generated, so that the gastric mucosa is damaged, clinical diseases are diversified, and the patient often has sour regurgitation, eructation, satiety and the like, which are multiple times of the patient infected with the helicobacter pylori than the patient not infected with the helicobacter pylori. (4) Helicobacter pylori infection is generally not particularly marked, and it is generally judged by examination whether or not there is helicobacter pylori infection, which is a pathogenic bacterium that easily induces gastrointestinal disease.
At present, the positive treatment of the helicobacter pylori usually takes antibiotics, however, the antibiotics treatment is difficult to completely eliminate after the helicobacter pylori is infected, most people carry bacteria for life, and the stomach is injured after the antibiotics are often taken. In response, the inventor has conducted a great deal of research on the above and consults a great number of cases to develop a traditional Chinese medicine capable of eradicating helicobacter pylori.
Disclosure of Invention
The invention aims to make up the defects of the prior art and provides a traditional Chinese medicine mixture for treating helicobacter pylori and a preparation method thereof.
The invention is realized by the following technical scheme:
a traditional Chinese medicine mixture for treating helicobacter pylori is prepared from the following raw material medicines in parts by weight:
10-20 parts of radix scutellariae, 6-10 parts of rheum officinale, 25-35 parts of hedyotis diffusa, 8-15 parts of coptis chinensis, 25-35 parts of dandelion, 25-35 parts of sweet wormwood, 8-15 parts of caulis perllae, 8-15 parts of costus root, 2-5 parts of pseudo-ginseng powder, 10-20 parts of cardamom, 10-20 parts of eupatorium fortunei, 8-15 parts of white paeony root, 3-9 parts of raw liquorice, 8-15 parts of bamboo leaves and 10-20 parts of semen coicis.
The mixture is prepared from the following raw material medicines in parts by weight:
15 of radix scutellariae, 8 of rheum officinale, 30 of hedyotis diffusa, 10 of coptis chinensis, 30 of dandelion, 30 of sweet wormwood, 10 of caulis perllae, 10 of costustoot, 3 of pseudo-ginseng powder, 15 of cardamom, 15 of eupatorium, 10 of white peony root, 6 of raw liquorice, 10 of bamboo leaves and 15 of coix seeds.
A preparation method of a traditional Chinese medicine mixture for treating helicobacter pylori comprises the following specific steps:
(1) mixing Scutellariae radix, radix et rhizoma Rhei, caulis Perillae, fructus Amomi rotundus, and folium Bambusae, grinding into powder, and extracting the medicinal powder with ethanol to obtain Chinese medicinal extract;
(2) cleaning herba Hedyotidis Diffusae, Coptidis rhizoma, herba Taraxaci, and herba Artemisiae Annuae, decocting in a pot, and filtering to obtain medicinal liquid;
(3) uniformly mixing the traditional Chinese medicine extract obtained in the step (1) and the liquid medicine obtained in the step (2), heating to boil, cooling, and storing in a thermostat at 3-8 ℃ for later use;
(4) placing radix aucklandiae, Notoginseng radix powder, herba Eupatorii, radix Paeoniae alba, Glycyrrhrizae radix and Coicis semen into casserole, adding clear water, soaking for 10-20min, decocting with strong fire to boil, decocting with slow fire for 40-50min, pouring out the medicinal liquid, adding clear water, decocting with strong fire to boil, decocting with slow fire for 30-40min, pouring out the medicinal liquid, mixing the two obtained medicinal liquids, and storing in 3-5 deg.C thermostat;
(5) and (4) mixing the liquid medicines obtained in the step (3) and the step (4), adding a honey sweetening agent, mixing uniformly, and filtering to obtain the traditional Chinese medicine mixture.
The traditional Chinese medicine used in the invention comprises:
the radix scutellariae is bitter in taste and cold in nature, and has the efficacies of clearing heat and drying dampness, purging fire and removing toxicity, stopping bleeding, preventing miscarriage and the like. It can be used for treating epidemic febrile disease, upper respiratory infection, cough due to lung heat, yellow gallbladder due to damp-heat, pneumonia, dysentery, hemoptysis, conjunctival congestion, threatened abortion, hypertension, carbuncle, furuncle, and sore.
Da Huang purges heat-toxin, breaks accumulation and stagnation, and moves blood stasis. To dredge all qi, regulate blood and vessels, benefit joints, purge plastic stagnation, damp-qi, abnormal cold and heat in limbs, warm miasma and phlegm, and relieve constipation.
All-grass of hundred-flower snakehead is slightly bitter, sweet and cold in taste. Entering the stomach, large intestine and small intestine channels, bitter cold clearing away heat and toxic material, sweet cold clearing away damp-heat, and has strong effects of removing toxic substance and resolving carbuncle for carbuncle swelling, pharyngalgia, snake wound, etc. It is commonly used to treat sore, sore throat, abdominal pain due to intestinal abscess, and venomous snake bite, and also used to treat stranguria due to heat-evil, pain with astringency, and dysuria.
Coptis root, rhizoma Coptidis enters the heart, spleen, stomach, liver, gallbladder and large intestine meridians. Clear heat and dry dampness, purge fire and remove toxicity. Mainly treats damp-heat fullness, vomiting and acid regurgitation, diarrhea, jaundice, high fever and coma, hyperactivity of heart-fire, vexation and insomnia, palpitation and restlessness, blood heat and hematemesis and epistaxis, conjunctival congestion, toothache, diabetes, carbuncle and swelling and sore; it is used externally to treat eczema, eczema and purulent ear canal.
The dandelion has the effects of clearing away heat and toxic materials, eliminating carbuncle, dissipating stagnation, invigorating stomach and healing ulcer, and has certain curative effects on chronic gastritis, gastric ulcer and helicobacter pylori infection because the dandelion is found to have good stomach-invigorating and gallbladder-benefiting effects and anti-ulcer effects by the current research; it can be used for treating damp-heat jaundice, urinary tract infection, and urinary calculus with symptoms of red heat and pain. Dandelion also has certain efficacy of clearing liver and improving vision, and is used for blood-shot eyes with swelling and pain caused by liver fire flaming up.
Sweet wormwood herb has the effects of clearing heat, cooling blood, relieving steaming, relieving summer-heat, dispelling wind and relieving itching, and is used as an antipyretic for tidal fever due to yin deficiency, and also has the effects of relieving night sweat, heatstroke and the like.
Caulis Perillae has mild antipyretic effect; has effects in promoting secretion of digestive juice and promoting gastrointestinal peristalsis; can reduce bronchial secretion and relieve bronchospasm.
Mu Xiang is pungent, bitter and warm. It enters spleen, stomach, large intestine, triple energizer and gallbladder meridians. Move qi and alleviate pain, invigorate spleen and promote digestion. Can be used for treating chest and hypochondrium, abdominal distention and pain, dysentery with diarrhea, tenesmus, dyspepsia, and anorexia. Roasted Aucklandia lappa Decne, radix aucklandiae and Cornus Sessima to relieve diarrhea. Can be used for treating diarrhea and abdominal pain.
The notoginseng powder has the best effects of enriching blood, removing stasis and bleeding, and promoting the circulation of qi and tonifying, and is the most precious of the medicines. Pseudo-ginseng is eaten raw, stasis is removed, tissue regeneration is promoted, swelling is reduced, pain is relieved, bleeding is stopped, blood stasis is not left, and new blood is not injured when blood flows; it is taken well to tonify and strengthen body. It also has effects in dilating blood vessel, relieving pain, relieving fatigue, and improving learning and memory. Has anti-inflammatory effect.
Has the function of immunomodulator, and can restore too high or too low immune response to normal, but does not interfere normal immune response of organism. Anti-tumor effect; inhibiting scar hyperplasia. Has antiaging and antioxidant effects. Reducing blood lipid and cholesterol.
Round cardamom is pungent in flavor; and (4) temperature. Move qi and stimulate appetite. Primary epigastric pain; dyspepsia is caused.
The eupatorium fortunei has the advantages of full plant, mild property, pungent taste, dampness elimination, stomach strengthening and summer heat clearing.Headache due to summer-heat and dampness; internal retention of moisture; epigastric fullness without hunger; nausea and vomiting; sweet and greasy in mouth; the query is resolved. Can be used for treating damp stagnation, gastric fullness, emesis, halitosis, sialorrhea, summer-heat dampness, headache, and chest distress.
Radix Paeoniae alba has effects of nourishing blood, regulating menstruation, astringing yin, arresting sweating, softening liver, relieving pain, and suppressing liver yang. It is commonly used for blood deficiency and chlorosis, irregular menstruation, spontaneous perspiration, night sweat, hypochondriac pain, abdominal pain, limb spasm and pain, headache and vertigo.
Raw licorice tonifies qi and strengthens the middle; relieving spasm and pain; moistening lung to arrest cough; purging pathogenic fire and removing toxic substances; harmonize the drugs. Mainly lassitude and poor appetite; emaciation and yellow face; palpitation and shortness of breath; abdominal pain and loose stool; limb spasm and pain; irritability; cough and asthma; swollen and sore throat; carbuncle sore and swelling pain; infantile fetal toxicity; and drug and food poisoning.
The bamboo leaves have the effects of clearing heat, relieving restlessness, promoting the production of body fluid and promoting urination. Can be used for treating fever polydipsia, infantile convulsion, cough with regurgitation, hematemesis, oliguria with reddish urine, aphtha, and tongue sore.
Coix seed is sweet and light in flavor and cool in nature. It enters spleen, stomach and lung meridians. Has effects in promoting water penetration, removing dampness, invigorating spleen, relieving diarrhea, relieving arthralgia, expelling pus, removing toxic substance, and resolving hard mass. Can be used for treating edema, loempe, dysuresia, spleen deficiency, diarrhea, damp arthralgia, spasm, pulmonary abscess, and intestinal abscess; wart, cancerous protuberance.
The invention has the advantages that: (1) the formula has reasonable compatibility, has the effects of inhibiting bacteria and pyloric obstruction, can detoxify, resist bacteria, prevent cancer, repair ulcer, relieve the symptoms of helicobacter pylori infection such as acid regurgitation, eructation, pyloric obstruction and the like, and further can effectively control and radically cure the helicobacter pylori infection.
(2) The pharmaceutical composition has stronger inhibiting and killing effects on helicobacter pylori, has higher curative effect on helicobacter pylori infection, has no adverse reaction and toxic or side effect after long-term administration, and reduces the treatment cost by more than 60 percent compared with the current western medicines for treating the disease.
Detailed Description
A traditional Chinese medicine mixture for treating helicobacter pylori is prepared from the following raw material medicines in parts by weight:
15 of radix scutellariae, 8 of rheum officinale, 30 of hedyotis diffusa, 10 of coptis chinensis, 30 of dandelion, 30 of sweet wormwood, 10 of caulis perllae, 10 of costustoot, 3 of pseudo-ginseng powder, 15 of cardamom, 15 of eupatorium, 10 of white peony root, 6 of raw liquorice, 10 of bamboo leaves and 15 of coix seeds.
A preparation method of a traditional Chinese medicine mixture for treating helicobacter pylori comprises the following specific steps:
(1) mixing Scutellariae radix, radix et rhizoma Rhei, caulis Perillae, fructus Amomi rotundus, and folium Bambusae, grinding into powder, and extracting the medicinal powder with ethanol to obtain Chinese medicinal extract;
(2) cleaning herba Hedyotidis Diffusae, Coptidis rhizoma, herba Taraxaci, and herba Artemisiae Annuae, decocting in a pot, and filtering to obtain medicinal liquid;
(3) uniformly mixing the traditional Chinese medicine extract obtained in the step (1) and the liquid medicine obtained in the step (2), heating to boil, cooling, and storing in a thermostat at 3-8 ℃ for later use;
(4) placing radix aucklandiae, Notoginseng radix powder, herba Eupatorii, radix Paeoniae alba, Glycyrrhrizae radix and Coicis semen into casserole, adding clear water, soaking for 10-20min, decocting with strong fire to boil, decocting with slow fire for 40-50min, pouring out the medicinal liquid, adding clear water, decocting with strong fire to boil, decocting with slow fire for 30-40min, pouring out the medicinal liquid, mixing the two obtained medicinal liquids, and storing in 3-5 deg.C thermostat;
(5) and (4) mixing the liquid medicines obtained in the step (3) and the step (4), adding a honey sweetening agent, mixing uniformly, and filtering to obtain the traditional Chinese medicine mixture.
Typical case 1: in any case, male, age 55, often has sour regurgitation, heartburn, stomachache and halitosis, and after hospital visits, the helicobacter pylori test results are as follows: positive + Dpm 68; the doctor suggests: treated with normal eradication of Hp and reviewed immediately after treatment was complete. After the traditional Chinese medicine mixture is taken three times a day and 1 bottle is taken once, after one course of treatment, the symptoms are relieved, the medicine is taken for 2 courses of treatment, the symptoms are completely disappeared, and Hp (-) is rechecked.
Typical case 2: wangzhi, age 45, male, epigastric discomfort, dull pain, sometimes with symptoms of belching, acid regurgitation, nausea, vomiting, hospital visit, C =102 positive Hp (+). After the traditional Chinese medicine mixture is taken three times a day and 1 bottle once, after one course of treatment, the symptoms are relieved and reviewed, C =60 and Hp (+) is positive, the medicine is continuously taken for 2 courses of treatment, the symptoms are completely disappeared, and Hp (-) is reviewed.
Typical case 3: certain young people, women, age 36 often have sour regurgitation, belching and satiety, and are easy to diarrhea, and the detection of carbon 14: helicobacter pylori testing: positive, taking the Chinese medicine mixture three times a day, 1 bottle once, after one course of treatment, the symptoms disappear, and examining Hp (-).
Claims (3)
1. A traditional Chinese medicine mixture for treating helicobacter pylori is characterized in that: the mixture is prepared from the following raw material medicines in parts by weight:
10-20 parts of radix scutellariae, 6-10 parts of rheum officinale, 25-35 parts of hedyotis diffusa, 8-15 parts of coptis chinensis, 25-35 parts of dandelion, 25-35 parts of sweet wormwood, 8-15 parts of caulis perllae, 8-15 parts of costus root, 2-5 parts of pseudo-ginseng powder, 10-20 parts of cardamom, 10-20 parts of eupatorium fortunei, 8-15 parts of white paeony root, 3-9 parts of raw liquorice, 8-15 parts of bamboo leaves and 10-20 parts of semen coicis.
2. The traditional Chinese medicine mixture for treating helicobacter pylori according to claim 1, which is characterized in that: the mixture is prepared from the following raw material medicines in parts by weight:
15 of radix scutellariae, 8 of rheum officinale, 30 of hedyotis diffusa, 10 of coptis chinensis, 30 of dandelion, 30 of sweet wormwood, 10 of caulis perllae, 10 of costustoot, 3 of pseudo-ginseng powder, 15 of cardamom, 15 of eupatorium, 10 of white peony root, 6 of raw liquorice, 10 of bamboo leaves and 15 of coix seeds.
3. A preparation method of a traditional Chinese medicine mixture for treating helicobacter pylori is characterized by comprising the following steps: the method comprises the following specific steps:
(1) mixing Scutellariae radix, radix et rhizoma Rhei, caulis Perillae, fructus Amomi rotundus, and folium Bambusae, grinding into powder, and extracting the medicinal powder with ethanol to obtain Chinese medicinal extract;
(2) cleaning herba Hedyotidis Diffusae, Coptidis rhizoma, herba Taraxaci, and herba Artemisiae Annuae, decocting in a pot, and filtering to obtain medicinal liquid;
(3) uniformly mixing the traditional Chinese medicine extract obtained in the step (1) and the liquid medicine obtained in the step (2), heating to boil, cooling, and storing in a thermostat at 3-8 ℃ for later use;
(4) placing radix aucklandiae, Notoginseng radix powder, herba Eupatorii, radix Paeoniae alba, Glycyrrhrizae radix and Coicis semen into casserole, adding clear water, soaking for 10-20min, decocting with strong fire to boil, decocting with slow fire for 40-50min, pouring out the medicinal liquid, adding clear water, decocting with strong fire to boil, decocting with slow fire for 30-40min, pouring out the medicinal liquid, mixing the two obtained medicinal liquids, and storing in 3-5 deg.C thermostat;
(5) and (4) mixing the liquid medicines obtained in the step (3) and the step (4), adding a honey sweetening agent, mixing uniformly, and filtering to obtain the traditional Chinese medicine mixture.
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