CN111743994A - Traditional Chinese medicine preparation for warming middle-jiao and invigorating spleen and preparation method thereof - Google Patents

Traditional Chinese medicine preparation for warming middle-jiao and invigorating spleen and preparation method thereof Download PDF

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CN111743994A
CN111743994A CN202010756692.8A CN202010756692A CN111743994A CN 111743994 A CN111743994 A CN 111743994A CN 202010756692 A CN202010756692 A CN 202010756692A CN 111743994 A CN111743994 A CN 111743994A
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parts
monkshood
chinese medicine
traditional chinese
jiao
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陈家进
濮均文
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NANJING TONGRENTANG PHARMACEUTICAL CO Ltd
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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Abstract

The invention discloses a traditional Chinese medicine preparation for warming middle-jiao and strengthening spleen, and particularly relates to the technical field of traditional Chinese medicine preparations, which comprises the following raw materials: monkshood, codonopsis pilosula, fried bighead atractylodes rhizome, dried ginger, liquorice, poria cocos, astragalus mongholicus, rhizoma atractylodis 120-130 parts, mangnolia officinalis, eucommia ulmoides, dried orange peel and ginseng. According to the invention, the poria cocos, the astragalus membranaceus, the rhizoma atractylodis, the mangnolia officinalis, the pericarpium citri reticulatae and the eucommia ulmoides are added, the poria cocos, the monkshood, the astragalus membranaceus, the codonopsis pilosula and the fried bighead atractylodes rhizome have auxiliary effects, the effects of tonifying spleen, promoting diuresis and excreting dampness are achieved, good treatment effects are achieved on spleen, stomach, liver and kidney, the medicines supplement each other, and the treatment effect is good; the dried orange peel is distilled to extract volatile oil, then water extraction and ethanol extraction are carried out, and the ethanol extraction and the water extraction are mixed and concentrated into dried orange peel extract, so that the measurement of the hesperidin component in the traditional Chinese medicine preparation is convenient, and the content of the hesperidin is high.

Description

Traditional Chinese medicine preparation for warming middle-jiao and invigorating spleen and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine preparation for warming middle-jiao and strengthening spleen and a preparation method thereof.
Background
The Chinese medicinal preparation is any medicament which is required to be prepared into a form suitable for medical or preventive application before clinical use, and is called a preparation form, such as tablets, injections, aerosols, pills, powders, ointments and the like.
When gastrointestinal discomfort occurs, some people can have stomachache and some people can have diarrhea, and timely medication should be selected for treatment under any condition so as to avoid more serious diseases and intestinal tract diseases, even some people become chronic diseases, and a Chinese patent medicine for warming middle-jiao and tonifying spleen is preferably selected for treatment under the condition, so that the Chinese patent medicine is mild and has little side effect.
The traditional Chinese medicine preparation for warming middle-jiao and strengthening spleen is prepared from monkshood, codonopsis pilosula, fried bighead atractylodes rhizome, dried ginger and liquorice, and has insufficient treatment effect on spleen and stomach.
Disclosure of Invention
In order to overcome the above defects of the prior art, the embodiment of the invention provides a traditional Chinese medicine preparation for warming middle-jiao and invigorating spleen and a preparation method thereof, and the invention aims to solve the following problems: how to improve the treatment of the traditional Chinese medicine preparation on the spleen and the stomach.
In order to achieve the purpose, the invention provides the following technical scheme: a traditional Chinese medicine preparation for warming middle-jiao and strengthening spleen comprises the following raw materials in parts by weight: 80-100 parts of monkshood, 220 parts of codonopsis pilosula 180-.
In a preferred embodiment, the feed comprises the following raw materials in parts by weight: 80 parts of monkshood, 180 parts of codonopsis pilosula, 130 parts of fried bighead atractylodes rhizome, 80 parts of dried ginger, 80 parts of liquorice, 60 parts of poria cocos, 80 parts of astragalus membranaceus, 120 parts of rhizoma atractylodis, 100 parts of mangnolia officinalis, 50 parts of eucommia ulmoides, 60 parts of dried orange peel and 80 parts of ginseng.
In a preferred embodiment, the feed comprises the following raw materials in parts by weight: 90 parts of monkshood, 200 parts of codonopsis pilosula, 150 parts of fried bighead atractylodes rhizome, 90 parts of dried ginger, 90 parts of liquorice, 70 parts of poria cocos, 90 parts of astragalus membranaceus, 125 parts of rhizoma atractylodis, 110 parts of mangnolia officinalis, 65 parts of eucommia ulmoides, 70 parts of dried orange peel and 90 parts of ginseng.
In a preferred embodiment, the feed comprises the following raw materials in parts by weight: 100 parts of monkshood, 220 parts of codonopsis pilosula, 170 parts of fried bighead atractylodes rhizome, 100 parts of dried ginger, 100 parts of liquorice, 80 parts of poria cocos, 100 parts of astragalus membranaceus, 130 parts of rhizoma atractylodis, 120 parts of mangnolia officinalis, 80 parts of eucommia ulmoides, 80 parts of dried orange peel and 100 parts of ginseng.
In a preferred embodiment, the monkshood is prepared from monkshood, and the weight part ratio of the monkshood to the liquorice to the dried ginger is 1: 1.
the invention also provides a preparation method of the traditional Chinese medicine preparation for warming middle-jiao and strengthening spleen, which comprises the following specific preparation steps:
the method comprises the following steps: weighing the monkshood, the codonopsis pilosula, the fried bighead atractylodes rhizome, the dried ginger, the liquorice, the poria cocos, the astragalus mongholicus, the rhizoma atractylodis, the mangnolia officinalis, the eucommia ulmoides, the dried orange peel and the ginseng in parts by weight, respectively putting the weighed monkshood, the astragalus mongholicus, the fried bighead atractylodes rhizome, the dried ginger, the poria cocos, the rhizoma atractylodis and the ginseng into a grinding machine for grinding and grinding, and screening the ground monkshood, the astragalus mongholicus, the fried bighead atractylodes rhizome, the dried ginger;
step two: distilling the weighed dried orange peel by using water vapor to extract volatile oil for later use; extracting the residue with water, mixing the water extractive solutions, and concentrating to obtain concentrated solution; adding 55-65% ethanol solution into the residue, reflux extracting for 2-3 times, filtering, mixing filtrates, recovering ethanol to obtain ethanol extractive solution, mixing the ethanol extractive solution and the water extractive solution, and concentrating to obtain pericarpium Citri Tangerinae extract;
step three: decocting radix Codonopsis, Glycyrrhrizae radix, cortex Magnolia officinalis and Eucommiae cortex with water twice, mixing decoctions, filtering, and concentrating the filtrate to obtain soft extract;
step four: percolating the parched Atractylodis rhizoma, Zingiberis rhizoma and Poria with 55-65% ethanol as solvent, collecting percolate, recovering ethanol, and concentrating to obtain soft extract;
step five: uniformly mixing the monkshood, the astragalus, the rhizoma atractylodis and the ginseng screened in the step one, then mixing with the dried orange peel extract in the step two, the filtrate thick paste in the step three and the percolate thick paste in the step four, and uniformly stirring;
step six: adding refined honey, water and the volatile oil obtained in the step two into the mixed liquid obtained in the step five, and preparing water-honeyed pills.
In a preferred embodiment, the monkshood, the astragalus, the rhizoma atractylodis and the ginseng in the first step are all screened by a 80-mesh sieve, and the roasted rhizoma atractylodis macrocephalae, the dried ginger and the poria are all screened by a 30-mesh sieve in the first step.
In a preferred embodiment, the first decoction time in the third step is 2-3h, the second decoction time is 3-3.5h, and the decoctions are combined, filtered, cooled and concentrated at 20 ℃.
In a preferred embodiment, in the fifth step, stirring is performed by using an electromagnetic stirrer, the stirring time is 30 minutes, and the stirring temperature is controlled to be 30-35 ℃.
In a preferred embodiment, the mixed solution, the refined honey, the water and the volatile oil in the sixth step are uniformly mixed by an electromagnetic stirrer, and 40-60g of refined honey and 20ml of water are added to every 100ml of the mixture.
The invention has the technical effects and advantages that:
1. according to the traditional Chinese medicine preparation for warming middle-jiao and strengthening spleen prepared by adopting the raw material formula, by adding the astragalus and the eucommia, the astragalus has the functions of enhancing the immunity of an organism, protecting the liver, promoting urination, resisting aging, resisting stress, reducing blood pressure, resisting bacteria widely and the like, tonifying qi and strengthening exterior, the compatibility of the astragalus and the monkshood has the effects of warming and tonifying spleen and kidney and tonifying fire and earth, and the eucommia is sweet and warm and is good at tonifying liver and kidney, and has the effects of enhancing liver and kidney and strengthening waist and knees when being used with the monkshood; the effects of strengthening spleen and eliminating dampness and descending qi and eliminating fullness can be enhanced by adding the atractylodes rhizome and the magnolia bark, wherein the atractylodes rhizome is bitter and warm, is good at eliminating dampness and strengthening spleen, and the magnolia bark is bitter, warm and pungent, is good at eliminating dampness and eliminating fullness; the poria cocos, the monkshood, the astragalus membranaceus, the codonopsis pilosula and the bighead atractylodes rhizome have auxiliary effects, and have the effects of tonifying spleen, promoting diuresis and excreting dampness;
2. the method extracts volatile oil from dried orange peel by distillation, then carries out water extraction and ethanol extraction, and mixes and concentrates ethanol extraction and water extraction solution into dried orange peel extract, and the dried orange peel extract is mixed with other components, so that the measurement of hesperidin in the traditional Chinese medicine preparation is convenient, the hesperidin content is high, and the treatment effect on organisms is better.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
the invention provides a traditional Chinese medicine preparation for warming middle-jiao and strengthening spleen, which comprises the following raw materials in parts by weight: 80 parts of monkshood, 180 parts of codonopsis pilosula, 130 parts of fried bighead atractylodes rhizome, 80 parts of dried ginger, 80 parts of liquorice, 60 parts of poria cocos, 80 parts of astragalus membranaceus, 120 parts of rhizoma atractylodis, 100 parts of mangnolia officinalis, 50 parts of eucommia ulmoides, 60 parts of dried orange peel and 80 parts of ginseng.
In a preferred embodiment, the monkshood is prepared from monkshood, and the weight part ratio of the monkshood to the liquorice to the dried ginger is 1: 1.
the invention also provides a preparation method of the traditional Chinese medicine preparation for warming middle-jiao and strengthening spleen, which comprises the following specific preparation steps:
the method comprises the following steps: weighing the monkshood, the codonopsis pilosula, the fried bighead atractylodes rhizome, the dried ginger, the liquorice, the poria cocos, the astragalus mongholicus, the rhizoma atractylodis, the mangnolia officinalis, the eucommia ulmoides, the dried orange peel and the ginseng in parts by weight, respectively putting the weighed monkshood, the astragalus mongholicus, the fried bighead atractylodes rhizome, the dried ginger, the poria cocos, the rhizoma atractylodis and the ginseng into a grinding machine for grinding and grinding, and screening the ground monkshood, the astragalus mongholicus, the fried bighead atractylodes rhizome, the dried ginger;
step two: distilling the weighed dried orange peel by using water vapor to extract volatile oil for later use; extracting the residue with water, mixing the water extractive solutions, and concentrating to obtain concentrated solution; adding 55% ethanol solution into the residue, reflux extracting for 3 times, filtering, mixing filtrates, recovering ethanol to obtain ethanol extractive solution, mixing the ethanol extractive solution and the water extractive solution, and concentrating to obtain pericarpium Citri Tangerinae extract;
step three: decocting radix Codonopsis, Glycyrrhrizae radix, cortex Magnolia officinalis and Eucommiae cortex with water twice, mixing decoctions, filtering, and concentrating the filtrate to obtain soft extract;
step four: percolating the parched Atractylodis rhizoma, Zingiberis rhizoma and Poria with 60% ethanol as solvent, collecting percolate, recovering ethanol, and concentrating to obtain soft extract;
step five: uniformly mixing the monkshood, the astragalus, the rhizoma atractylodis and the ginseng screened in the step one, then mixing with the dried orange peel extract in the step two, the filtrate thick paste in the step three and the percolate thick paste in the step four, and uniformly stirring;
step six: adding refined honey, water and the volatile oil obtained in the step two into the mixed liquid obtained in the step five, and preparing water-honeyed pills.
In a preferred embodiment, the monkshood, the astragalus, the rhizoma atractylodis and the ginseng in the first step are all screened by a 80-mesh sieve, and the roasted rhizoma atractylodis macrocephalae, the dried ginger and the poria are all screened by a 30-mesh sieve in the first step.
In a preferred embodiment, the first decoction time in the third step is 2 hours, the second decoction time is 3 hours, and the decoctions are combined, filtered, cooled and concentrated at 20 ℃.
In a preferred embodiment, in the fifth step, the stirring is performed by using an electromagnetic stirrer, the stirring time is 30 minutes, and the stirring temperature is controlled at 33 ℃.
In a preferred embodiment, the mixed solution, the refined honey, the water and the volatile oil in the sixth step are uniformly mixed by an electromagnetic stirrer, and 50g of refined honey and 20ml of water are added to every 100ml of the mixture.
Example 2:
a traditional Chinese medicine preparation for warming middle-jiao and strengthening spleen comprises the following raw materials in parts by weight: 90 parts of monkshood, 200 parts of codonopsis pilosula, 150 parts of fried bighead atractylodes rhizome, 90 parts of dried ginger, 90 parts of liquorice, 70 parts of poria cocos, 90 parts of astragalus membranaceus, 125 parts of rhizoma atractylodis, 110 parts of mangnolia officinalis, 65 parts of eucommia ulmoides, 70 parts of dried orange peel and 90 parts of ginseng.
In a preferred embodiment, the monkshood is prepared from monkshood, and the weight part ratio of the monkshood to the liquorice to the dried ginger is 1: 1.
the invention also provides a preparation method of the traditional Chinese medicine preparation for warming middle-jiao and strengthening spleen, which comprises the following specific preparation steps:
the method comprises the following steps: weighing the monkshood, the codonopsis pilosula, the fried bighead atractylodes rhizome, the dried ginger, the liquorice, the poria cocos, the astragalus mongholicus, the rhizoma atractylodis, the mangnolia officinalis, the eucommia ulmoides, the dried orange peel and the ginseng in parts by weight, respectively putting the weighed monkshood, the astragalus mongholicus, the fried bighead atractylodes rhizome, the dried ginger, the poria cocos, the rhizoma atractylodis and the ginseng into a grinding machine for grinding and grinding, and screening the ground monkshood, the astragalus mongholicus, the fried bighead atractylodes rhizome, the dried ginger;
step two: distilling the weighed dried orange peel by using water vapor to extract volatile oil for later use; extracting the residue with water, mixing the water extractive solutions, and concentrating to obtain concentrated solution; adding 60% ethanol solution into the residue, reflux extracting for 3 times, filtering, mixing filtrates, recovering ethanol to obtain ethanol extractive solution, mixing the ethanol extractive solution and the water extractive solution, and concentrating to obtain pericarpium Citri Tangerinae extract;
step three: decocting radix Codonopsis, Glycyrrhrizae radix, cortex Magnolia officinalis and Eucommiae cortex with water twice, mixing decoctions, filtering, and concentrating the filtrate to obtain soft extract;
step four: percolating the parched Atractylodis rhizoma, Zingiberis rhizoma and Poria with 60% ethanol as solvent, collecting percolate, recovering ethanol, and concentrating to obtain soft extract;
step five: uniformly mixing the monkshood, the astragalus, the rhizoma atractylodis and the ginseng screened in the step one, then mixing with the dried orange peel extract in the step two, the filtrate thick paste in the step three and the percolate thick paste in the step four, and uniformly stirring;
step six: adding refined honey, water and the volatile oil obtained in the step two into the mixed liquid obtained in the step five, and preparing water-honeyed pills.
In a preferred embodiment, the monkshood, the astragalus, the rhizoma atractylodis and the ginseng in the first step are all screened by a 80-mesh sieve, and the roasted rhizoma atractylodis macrocephalae, the dried ginger and the poria are all screened by a 30-mesh sieve in the first step.
In a preferred embodiment, the first decoction time in the third step is 3 hours, the second decoction time is 3 hours, and the decoctions are combined, filtered, cooled and concentrated at 20 ℃.
In a preferred embodiment, in the fifth step, the stirring is performed by using an electromagnetic stirrer, the stirring time is 30 minutes, and the stirring temperature is controlled at 33 ℃.
In a preferred embodiment, the mixed solution, the refined honey, the water and the volatile oil in the sixth step are uniformly mixed by an electromagnetic stirrer, and 50g of refined honey and 20ml of water are added to every 100ml of the mixture.
Example 3:
a traditional Chinese medicine preparation for warming middle-jiao and strengthening spleen comprises the following raw materials in parts by weight: 100 parts of monkshood, 220 parts of codonopsis pilosula, 170 parts of fried bighead atractylodes rhizome, 100 parts of dried ginger, 100 parts of liquorice, 80 parts of poria cocos, 100 parts of astragalus membranaceus, 130 parts of rhizoma atractylodis, 120 parts of mangnolia officinalis, 80 parts of eucommia ulmoides, 80 parts of dried orange peel and 100 parts of ginseng.
In a preferred embodiment, the monkshood is prepared from monkshood, and the weight part ratio of the monkshood to the liquorice to the dried ginger is 1: 1.
the invention also provides a preparation method of the traditional Chinese medicine preparation for warming middle-jiao and strengthening spleen, which comprises the following specific preparation steps:
the method comprises the following steps: weighing the monkshood, the codonopsis pilosula, the fried bighead atractylodes rhizome, the dried ginger, the liquorice, the poria cocos, the astragalus mongholicus, the rhizoma atractylodis, the mangnolia officinalis, the eucommia ulmoides, the dried orange peel and the ginseng in parts by weight, respectively putting the weighed monkshood, the astragalus mongholicus, the fried bighead atractylodes rhizome, the dried ginger, the poria cocos, the rhizoma atractylodis and the ginseng into a grinding machine for grinding and grinding, and screening the ground monkshood, the astragalus mongholicus, the fried bighead atractylodes rhizome, the dried ginger;
step two: distilling the weighed dried orange peel by using water vapor to extract volatile oil for later use; extracting the residue with water, mixing the water extractive solutions, and concentrating to obtain concentrated solution; adding 65% ethanol solution into the residue, reflux extracting for 3 times, filtering, mixing filtrates, recovering ethanol to obtain ethanol extractive solution, mixing the ethanol extractive solution and the water extractive solution, and concentrating to obtain pericarpium Citri Tangerinae extract;
step three: decocting radix Codonopsis, Glycyrrhrizae radix, cortex Magnolia officinalis and Eucommiae cortex with water twice, mixing decoctions, filtering, and concentrating the filtrate to obtain soft extract;
step four: percolating the parched Atractylodis rhizoma, Zingiberis rhizoma and Poria with 60% ethanol as solvent, collecting percolate, recovering ethanol, and concentrating to obtain soft extract;
step five: uniformly mixing the monkshood, the astragalus, the rhizoma atractylodis and the ginseng screened in the step one, then mixing with the dried orange peel extract in the step two, the filtrate thick paste in the step three and the percolate thick paste in the step four, and uniformly stirring;
step six: adding refined honey, water and the volatile oil obtained in the step two into the mixed liquid obtained in the step five, and preparing water-honeyed pills.
In a preferred embodiment, the monkshood, the astragalus, the rhizoma atractylodis and the ginseng in the first step are all screened by a 80-mesh sieve, and the roasted rhizoma atractylodis macrocephalae, the dried ginger and the poria are all screened by a 30-mesh sieve in the first step.
In a preferred embodiment, the first decoction time in the third step is 3 hours, the second decoction time is 3.5 hours, and the decoctions are combined, filtered, cooled and concentrated at 20 ℃.
In a preferred embodiment, in the fifth step, the stirring is performed by using an electromagnetic stirrer, the stirring time is 30 minutes, and the stirring temperature is controlled at 33 ℃.
In a preferred embodiment, the mixed solution, the refined honey, the water and the volatile oil in the sixth step are uniformly mixed by an electromagnetic stirrer, and 50g of refined honey and 20ml of water are added to every 100ml of the mixture.
Respectively measuring the content of aconitine and hesperidin in the Chinese medicinal preparation by high performance liquid chromatography, wherein the measurement results are shown in the table I:
aconitine content (. rho./ng. L.)-1) Hesperidin content (mg/g)
Example 1 0.73 2.53
Example 2 0.70 2.56
Example 3 0.71 2.54
Watch 1
As can be seen from the above table, the Chinese medicinal preparation for warming middle-jiao and invigorating spleen comprises the following raw materials in parts by weight: 90 parts of monkshood, 200 parts of codonopsis pilosula, 150 parts of fried bighead atractylodes rhizome, 90 parts of dried ginger, 90 parts of liquorice, 70 parts of poria cocos, 90 parts of astragalus membranaceus, 125 parts of rhizoma atractylodis, 110 parts of mangnolia officinalis, 65 parts of eucommia ulmoides, 70 parts of dried orange peel and 90 parts of ginseng, the aconitine content is low, the hesperidin content is high, and the spleen strengthening effect on organisms is better.
The patients using the traditional Chinese medicine reagent produced in example 2 were investigated, and the investigation number was 20, the patients aged 45-55 years, and the symptoms of the disorder, the discomfort of the spleen and the stomach, and the symptoms of diarrhea and pain were frequently accompanied. The survey results are shown in table two:
Figure BDA0002611804340000081
Figure BDA0002611804340000091
watch two
According to the above table, the traditional Chinese medicine preparation produced by the invention has a better treatment effect on the spleen and the stomach of a patient, the astragalus has the functions of enhancing the immunity of the organism, protecting the liver, promoting urination, resisting aging, resisting stress, reducing blood pressure, resisting bacteria widely and the like, tonifying qi and strengthening exterior by adding the astragalus and the eucommia, the compatibility of the astragalus and the monkshood has the effects of warming and invigorating the spleen and the kidney and tonifying fire and earth, the eucommia is sweet and warm and is good at tonifying the liver and the kidney, and the effects of reinforcing the liver and the kidney and strengthening the waist and knees when being used with the monkshood; the effects of strengthening spleen and eliminating dampness and descending qi and eliminating fullness can be enhanced by adding the atractylodes rhizome and the magnolia bark, wherein the atractylodes rhizome is bitter and warm, is good at eliminating dampness and strengthening spleen, and the magnolia bark is bitter, warm and pungent, is good at eliminating dampness and eliminating fullness; the poria cocos, the monkshood, the astragalus membranaceus, the codonopsis pilosula and the bighead atractylodes rhizome have auxiliary effects, and have the effects of tonifying spleen, promoting diuresis and excreting dampness.
And finally: the above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that are within the spirit and principle of the present invention are intended to be included in the scope of the present invention.

Claims (10)

1. A traditional Chinese medicine preparation for warming middle-jiao and strengthening spleen is characterized in that: the feed comprises the following raw materials in parts by weight: 80-100 parts of monkshood, 220 parts of codonopsis pilosula 180-.
2. The traditional Chinese medicine preparation for warming middle-jiao and invigorating spleen according to claim 1, which is characterized in that: the feed comprises the following raw materials in parts by weight: 80 parts of monkshood, 180 parts of codonopsis pilosula, 130 parts of fried bighead atractylodes rhizome, 80 parts of dried ginger, 80 parts of liquorice, 60 parts of poria cocos, 80 parts of astragalus membranaceus, 120 parts of rhizoma atractylodis, 100 parts of mangnolia officinalis, 50 parts of eucommia ulmoides, 60 parts of dried orange peel and 80 parts of ginseng.
3. The traditional Chinese medicine preparation for warming middle-jiao and invigorating spleen according to claim 1, which is characterized in that: the feed comprises the following raw materials in parts by weight: 90 parts of monkshood, 200 parts of codonopsis pilosula, 150 parts of fried bighead atractylodes rhizome, 90 parts of dried ginger, 90 parts of liquorice, 70 parts of poria cocos, 90 parts of astragalus membranaceus, 125 parts of rhizoma atractylodis, 110 parts of mangnolia officinalis, 65 parts of eucommia ulmoides, 70 parts of dried orange peel and 90 parts of ginseng.
4. The traditional Chinese medicine preparation for warming middle-jiao and invigorating spleen according to claim 1, which is characterized in that: the feed comprises the following raw materials in parts by weight: 100 parts of monkshood, 220 parts of codonopsis pilosula, 170 parts of fried bighead atractylodes rhizome, 100 parts of dried ginger, 100 parts of liquorice, 80 parts of poria cocos, 100 parts of astragalus membranaceus, 130 parts of rhizoma atractylodis, 120 parts of mangnolia officinalis, 80 parts of eucommia ulmoides, 80 parts of dried orange peel and 100 parts of ginseng.
5. The traditional Chinese medicine preparation for warming middle-jiao and invigorating spleen according to claim 1, which is characterized in that: the monkshood is prepared from monkshood, and the weight ratio of the monkshood to the liquorice to the dried ginger is 1: 1.
6. the preparation method of the Chinese medicinal preparation for warming middle-jiao and invigorating spleen according to any one of claims 1 to 5, characterized in that: the preparation method comprises the following specific steps:
the method comprises the following steps: weighing the monkshood, the codonopsis pilosula, the fried bighead atractylodes rhizome, the dried ginger, the liquorice, the poria cocos, the astragalus mongholicus, the rhizoma atractylodis, the mangnolia officinalis, the eucommia ulmoides, the dried orange peel and the ginseng in parts by weight, respectively putting the weighed monkshood, the astragalus mongholicus, the fried bighead atractylodes rhizome, the dried ginger, the poria cocos, the rhizoma atractylodis and the ginseng into a grinding machine for grinding and grinding, and screening the ground monkshood, the astragalus mongholicus, the fried bighead atractylodes rhizome, the dried ginger;
step two: distilling the weighed dried orange peel by using water vapor to extract volatile oil for later use; extracting the residue with water, mixing the water extractive solutions, and concentrating to obtain concentrated solution; adding 55-65% ethanol solution into the residue, reflux extracting for 2-3 times, filtering, mixing filtrates, recovering ethanol to obtain ethanol extractive solution, mixing the ethanol extractive solution and the water extractive solution, and concentrating to obtain pericarpium Citri Tangerinae extract;
step three: decocting radix Codonopsis, Glycyrrhrizae radix, cortex Magnolia officinalis and Eucommiae cortex with water twice, mixing decoctions, filtering, and concentrating the filtrate to obtain soft extract;
step four: percolating the parched Atractylodis rhizoma, Zingiberis rhizoma and Poria with 55-65% ethanol as solvent, collecting percolate, recovering ethanol, and concentrating to obtain soft extract;
step five: uniformly mixing the monkshood, the astragalus, the rhizoma atractylodis and the ginseng screened in the step one, then mixing with the dried orange peel extract in the step two, the filtrate thick paste in the step three and the percolate thick paste in the step four, and uniformly stirring;
step six: adding refined honey, water and the volatile oil obtained in the step two into the mixed liquid obtained in the step five, and preparing water-honeyed pills.
7. The preparation method of the traditional Chinese medicine preparation for warming middle-jiao and invigorating spleen according to claim 6, characterized in that: and in the first step, the monkshood, the astragalus, the rhizoma atractylodis and the ginseng are screened by adopting a 80-mesh sieve, and the fried bighead atractylodes rhizome, the dried ginger and the poria are screened by adopting a 30-mesh sieve.
8. The preparation method of the traditional Chinese medicine preparation for warming middle-jiao and invigorating spleen according to claim 6, characterized in that: in the third step, the first decoction time is 2-3h, the second decoction time is 3-3.5h, and the decoction liquids are combined, filtered, cooled and concentrated at the temperature of 20 ℃.
9. The preparation method of the traditional Chinese medicine preparation for warming middle-jiao and invigorating spleen according to claim 6, characterized in that: and in the fifth step, stirring is carried out by using an electromagnetic stirrer for 30 minutes, and the stirring temperature is controlled to be 30-35 ℃.
10. The preparation method of the traditional Chinese medicine preparation for warming middle-jiao and invigorating spleen according to claim 6, characterized in that: and in the sixth step, the mixed solution, the refined honey, the water and the volatile oil are uniformly mixed by an electromagnetic stirrer, and 40-60g of refined honey and 20ml of water are added into every 100ml of the mixture.
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