CN111700965A - A Chinese medicinal external preparation for treating fungal infection - Google Patents

A Chinese medicinal external preparation for treating fungal infection Download PDF

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Publication number
CN111700965A
CN111700965A CN202010792294.1A CN202010792294A CN111700965A CN 111700965 A CN111700965 A CN 111700965A CN 202010792294 A CN202010792294 A CN 202010792294A CN 111700965 A CN111700965 A CN 111700965A
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China
Prior art keywords
parts
fungal infection
external preparation
weight
traditional chinese
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CN202010792294.1A
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Chinese (zh)
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仲崇允
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Individual
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Priority to CN202010792294.1A priority Critical patent/CN111700965A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964Anemarrhena
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a traditional Chinese medicine external preparation for treating fungal infection, which is prepared from the following raw material medicines in parts by weight: 2-4 parts of sulfur, cinnamomum japonicum and garden balsam seed; 6-12 parts by weight of rhizoma anemarrhenae; giant knotweed rhizome, bupleurum root and saddle leaf 9-18 weight portions. According to the traditional Chinese medicine external preparation for treating fungal infection, the raw materials are matched and coordinated with each other, so that the traditional Chinese medicine external preparation has a good curative effect on fungal infection.

Description

A Chinese medicinal external preparation for treating fungal infection
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine external preparation for treating fungal infection.
Background
Fungal infections are infectious skin diseases caused by dermatophytes, and body fungal infections are fungal infections occurring on the face, neck, trunk, limbs, and the like, and are also called round fungal infections and chiefly fungal infections. The fungal infection is caused by a trichofungal infection, a microsporum or an epidermoid fungal infection. The infection sources of the traditional Chinese medicine are mainly hand fungal infection, foot fungal infection, nail fungal infection, polluted clothes and the like. Common methods of treating fungal infections in western medicine: ketonic or itraconazole (sertralinol) for oral administration; externally applied mouldazole ointment, ketoconazole cream, dacron ointment, compound rebamipide liniment, compound formic acid liniment and the like. After the treatment, the body fungal infection or the femoral fungal infection is relatively reduced, and the body fungal infection reappears after the medicine is stopped. Currently, there are no specific drugs for treating fungal infections.
Disclosure of Invention
The invention aims to improve the defects of the prior art and provide the traditional Chinese medicine composition for treating fungal infection, which can effectively improve or even eliminate the clinical symptoms of patients and has the characteristics of obvious treatment effect, short treatment period, no toxic or side effect and the like.
The invention provides a traditional Chinese medicine for treating fungal infection, which is prepared from the following raw materials in parts by weight: 2-4 parts of sulfur, cinnamomum japonicum and garden balsam seed; 6-12 parts by weight of rhizoma anemarrhenae; giant knotweed rhizome, bupleurum root and saddle leaf 9-18 weight portions.
In a preferred embodiment, the traditional Chinese medicine composition for treating fungal infection consists of the following raw material medicines in parts by weight: 4 parts of sulfur, cinnamomum japonicum and garden balsam seed; 12 parts of rhizoma anemarrhenae; giant knotweed rhizome, bupleurum root and saddle leaf in 18 weight portions.
Wherein, cinnamon is pungent, sweet and hot in flavor. It enters kidney, spleen, heart and liver meridians. Tonify fire and strengthen yang, guide fire to the origin, dispel cold and alleviate pain, activate blood and dredge channels. Cinnamon has an obvious fungicidal effect.
Giant knotweed rhizome, slightly bitter and slightly cold. It enters liver, gallbladder and lung meridians. Dispel wind and remove dampness, dissipate blood stasis and relieve pain, relieve cough and resolve phlegm. Polygonum cuspidatum has strong bactericidal performance on deep red fungus-infected bacteria and interdigital fungus-infected bacteria which cause refractory fungus infection and pompholyx leucomycosis infection.
Zhi mu is bitter, sweet and cold. It enters lung, stomach and kidney meridians. Clear heat and purge fire, promote fluid production and moisten dryness. The rhizoma anemarrhenae decoction has stronger antibacterial effect on some common pathogenic dermatophyte infectious bacteria such as Klebsiella pneumoniae fungal infectious bacteria and Mongolian variants thereof, concentric trichome fungal infectious bacteria, Viola trichome fungal infectious bacteria, Rhodotrichum trichome infectious bacteria, flocculent epidermal fungal infectious bacteria, rust trichome fungal infectious bacteria, plantar trichome fungal infectious bacteria, interdigital trichome fungal infectious bacteria, dog microspore and the like on a saber culture medium.
Semen Impatientis slightly bitter, pungent and warm; has little toxicity. It enters lung and liver meridians. Break blood and soften hardness, remove food stagnation. The semen Impatientis extract also contains a certain amount of effective components with anti-inflammatory and antibacterial effects, and has obvious antibacterial effect on red epidermoid fungus infectious bacteria, violet hair fungus infectious bacteria and inguinal epidermoid fungus infectious bacteria, and golf epidermoid fungus infectious bacteria.
The bupleurum root is pungent; bitter; is cool in nature. Enter liver and gallbladder meridians. Wind dispelling and heat discharging; detoxify and detumescence. The traditional Chinese medicine liquid has a capability of killing red fungus infectious bacteria, and the inventor washes 10 patients infected by the fungus for about 10 years for 5-10 times, and the patients are all cured.
And (3) sulfur: an acid; heating; is toxic. Returning to the kidney; a spleen; liver; the large intestine channel. Tonifying fire and strengthening yang; warming spleen and relaxing bowels; kill parasites and relieve itching. Can be used for treating scabies; refractory fungal infections; baldness sores; pemphigus; eczema and carbuncle; carrying out erosion of the vulva; deep rooted carbuncle of yin type; malignant sores, etc.
Saddle leaf: remove damp toxin, remove putrefaction and promote granulation. Can be used for treating pemphigus, refractory fungal infection, skin eczema, skin ulcer, carbuncle, ulcer, burn, and scald.
The invention is prepared from Chinese traditional herbal medicines, and the Chinese traditional medicine for effectively treating fungal infection is combined by orderly matching certain natural extracts with definite components and clear effects.
The traditional Chinese medicine composition has the advantages of easily available raw materials, simple process, low cost and high efficiency, and is beneficial to pharmaceutical enterprises for medicine production and quality control; the product has low price and is easy to be accepted by patients.
The traditional Chinese medicine composition has a remarkable effect of treating fungal infection, and clinical experiment results show that the pruritus is relieved after the traditional Chinese medicine composition is applied for 1 time generally; the disease can be cured after 3-10 times.
The invention also provides an external preparation prepared from the traditional Chinese medicine composition for treating cellulitis, which comprises solution, tincture, spirit, powder, lotion, oil, emulsion, ointment, cataplasm, plaster, film coating agent, gel, aerosol and the like.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the present invention in any way, and it will be apparent to those skilled in the art that the above description of the present invention can be applied to various modifications, equivalent variations or modifications without departing from the spirit and scope of the present invention.

Claims (4)

1. A traditional Chinese medicine external preparation for treating fungal infection is characterized by comprising the following raw material medicines in parts by weight: 2-4 parts of sulfur, cinnamomum japonicum and garden balsam seed; 6-12 parts by weight of rhizoma anemarrhenae; giant knotweed rhizome, bupleurum root and saddle leaf 9-18 weight portions.
2. The traditional Chinese medicine external preparation for treating fungal infection according to claim 1, which is characterized by comprising the following raw material medicines in parts by weight: 4 parts of sulfur, cinnamomum japonicum and garden balsam seed; 12 parts of rhizoma anemarrhenae; giant knotweed rhizome, bupleurum root and saddle leaf in 18 weight portions.
3. An external preparation for treating fungal infection, which is prepared from the Chinese medicinal composition of any one of claims 1 or 2.
4. The external preparation for treating cellulitis according to claim 3, which comprises solution, tincture and spirit, powder, lotion, oil, emulsion, ointment, cataplasm, plaster, plastics, gel, aerosol, etc., preferably ointment, aerosol.
CN202010792294.1A 2020-08-09 2020-08-09 A Chinese medicinal external preparation for treating fungal infection Pending CN111700965A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010792294.1A CN111700965A (en) 2020-08-09 2020-08-09 A Chinese medicinal external preparation for treating fungal infection

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010792294.1A CN111700965A (en) 2020-08-09 2020-08-09 A Chinese medicinal external preparation for treating fungal infection

Publications (1)

Publication Number Publication Date
CN111700965A true CN111700965A (en) 2020-09-25

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010792294.1A Pending CN111700965A (en) 2020-08-09 2020-08-09 A Chinese medicinal external preparation for treating fungal infection

Country Status (1)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107397928A (en) * 2017-07-27 2017-11-28 四川聚豪生物科技有限公司 It is a kind of effectively to treat Chinese medicine composition of fungal infection and preparation method thereof
CN107582805A (en) * 2017-10-19 2018-01-16 广西民族大学 One kind controls beriberi
CN109646340A (en) * 2017-10-11 2019-04-19 谭友明 A kind of antibacterial Chinese herbal medicines extracting solution

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107397928A (en) * 2017-07-27 2017-11-28 四川聚豪生物科技有限公司 It is a kind of effectively to treat Chinese medicine composition of fungal infection and preparation method thereof
CN109646340A (en) * 2017-10-11 2019-04-19 谭友明 A kind of antibacterial Chinese herbal medicines extracting solution
CN107582805A (en) * 2017-10-19 2018-01-16 广西民族大学 One kind controls beriberi

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