CN111671883B

CN111671883B - Traditional Chinese medicine composition for treating ulcerative colitis in cooperation with moxibustion therapy and preparation method and application thereof

Info

Publication number: CN111671883B
Application number: CN202010641251.3A
Authority: CN
Inventors: 李博林; 王小天; 赵丹阳; 杜朋丽; 才艳茹
Original assignee: Hebei Province Hospital Of Cm
Current assignee: Hebei Province Hospital Of Cm
Priority date: 2020-07-06
Filing date: 2020-07-06
Publication date: 2022-03-29
Anticipated expiration: 2040-07-06
Also published as: CN111671883A

Abstract

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating ulcerative colitis by matching moxibustion therapy and a preparation method and application thereof. The composition comprises the following raw materials: herba Agastaches, Olibanum, flos Caryophylli, Myrrha, cortex Cinnamomi, ramulus Cinnamomi, Zingiberis rhizoma, fructus Amomi rotundus, fructus Chaenomelis, radix Angelicae Pubescentis, radix Angelicae sinensis, radix Angelicae Dahuricae and herba Lycopodii. The traditional Chinese medicine composition has the effects of regulating qi, promoting blood circulation and relieving pain, can quickly relieve symptoms of stomachache, diarrhea, mucopurulent bloody stool and the like when an ulcerative colitis patient is attacked by cooperating with acupuncture point moxibustion therapy, can also stimulate healthy qi of a human body, improve the immunologic function, maintain the remission, reduce attack times by regulating and protecting healthy qi and enhancing disease resistance, and gradually heal the disease.

Description

Traditional Chinese medicine composition for treating ulcerative colitis in cooperation with moxibustion therapy and preparation method and application thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating ulcerative colitis by matching moxibustion therapy and a preparation method and application thereof.

Background

Ulcerative Colitis (UC) is a chronic, nonspecific, inflammatory disease of the intestinal tract, with abdominal pain, diarrhea, tenesmus, mucopurulent bloody stool as the main clinical manifestations, and the etiology is not clear. The disease incidence rate rises year by year, the disease is often delayed and cannot be cured, and the disease attacks repeatedly, and the patient suffers from the pain all the year round, thus seriously affecting daily work and life. At present, both Chinese and western medicines have measures for treating UC, and the western medicine is commonly treated by aminosalicylic acid preparation, corticosteroid, immunosuppressant and the like in clinic, but the curative effect is not ideal, the relapse is easy, and the treatment cost is expensive; the traditional Chinese medicine mainly takes traditional Chinese medicine oral decoction as main part, the decoction is tedious, the treatment course is long, and the decoction is bitter, so that patients are not willing to accept the decoction, and the compliance is poor.

Disclosure of Invention

Aiming at the problems that western medicines for treating ulcerative colitis in the prior art are easy to relapse, expensive in cost and poor in compliance of traditional Chinese medicine oral decoction, the invention provides a traditional Chinese medicine composition for treating ulcerative colitis by matching moxibustion.

The invention also provides a preparation method of the traditional Chinese medicine composition for treating ulcerative colitis by matching moxibustion therapy.

The invention also provides application of the traditional Chinese medicine composition for treating ulcerative colitis by cooperating with moxibustion in preparing a moxibustion medicine for treating ulcerative colitis.

In order to achieve the purpose of the invention, the embodiment of the invention adopts the following technical scheme:

a traditional Chinese medicine composition for treating ulcerative colitis in cooperation with moxibustion therapy comprises the following raw materials in parts by weight: 10-20 parts of wrinkled gianthyssop herb, 9-20 parts of frankincense, 4-12 parts of clove, 9-20 parts of myrrh, 3-15 parts of cinnamon, 12-18 parts of cassia twig, 6-15 parts of dried ginger, 12-18 parts of cardamom, 6-12 parts of pawpaw, 6-15 parts of radix angelicae pubescentis, 10-20 parts of angelica, 6-15 parts of radix angelicae and 6-15 parts of lycopodium clavatum.

The traditional Chinese medicine composition has the effects of regulating qi, promoting blood circulation and relieving pain, can quickly relieve symptoms of abdominal pain, diarrhea, mucopurulent bloody stool and the like when UC patients are attacked by cooperating with acupuncture point moxibustion therapy, can also stimulate healthy qi of human bodies, improve the immunologic function, maintain the remission, reduce attack times by regulating and protecting healthy qi and enhancing the disease resistance, and gradually heal the diseases. The Chinese medicinal composition does not need to be taken orally, and can avoid the problem of poor compliance of oral decoction. The traditional Chinese medicine composition is low in price and low in treatment cost.

In the traditional Chinese medicines of the formula:

agastache rugosus is pungent in flavor and slightly warm in nature; resolving dampness, relieving vomit, and relieving summer-heat;

the frankincense is pungent and bitter in flavor and warm in nature; promoting blood circulation, activating qi-flowing, relieving pain, relieving swelling, and promoting granulation;

clove is pungent in flavor and warm in nature; warming the middle-jiao to lower adverse flow of qi, dispelling cold to relieve pain, warming kidney and tonifying yang;

myrrh is pungent, bitter and neutral in nature; promoting blood circulation, relieving pain, eliminating swelling, and promoting granulation;

cinnamon is pungent and sweet in flavor and is strongly hot in nature; tonifying fire and supporting yang, dispelling cold and relieving pain, warming channels and dredging collaterals, and guiding fire back to original position;

the cassia twig is pungent and sweet in flavor and warm in nature; inducing sweat to relieve muscles, warming and dredging channels and collaterals, supporting yang and regulating qi;

dry ginger is pungent in flavor and hot in nature; warming the middle-jiao to dispel cold, restoring yang to activate collaterals, warming the lung to resolve fluid retention;

round cardamom is pungent in flavor and warm in nature; resolve dampness, promote qi circulation, warm middle energizer and arrest vomiting;

the pawpaw is sour in taste and warm in nature; relaxing muscles and tendons, activating collateral flow, regulating stomach function, and eliminating dampness;

radix Angelicae Pubescentis is pungent and bitter in flavor and slightly warm in nature; dispel wind-damp, alleviate pain, release exterior;

chinese angelica root, radix Angelicae sinensis is sweet and pungent in flavor and warm in nature; enriching blood, regulating menstruation, promoting blood circulation, relieving pain, and loosening bowel to relieve constipation;

the angelica dahurica is pungent in flavor and warm in nature; relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, relieving pain, dredging nasal orifice, eliminating dampness, stopping leukorrhagia, relieving swelling, and expelling pus;

lycopodium clavatum is slightly bitter and pungent in flavor and warm in nature; dispelling pathogenic wind and removing dampness, relaxing muscles and tendons and activating collaterals;

in the traditional Chinese medicine composition, the Chinese angelica is pungent and capable of promoting the circulation of qi and warming the channels, and has the effects of promoting blood circulation, dispelling cold and relieving pain, and mainly treats various sores and ulcers; frankincense and myrrh, pungent in flavor and warm in property, activate blood, promote qi circulation, alleviate pain, resolve swelling and promote granulation, are the essential herbs for circulating the channels and collaterals in the invention. The angelica, the frankincense and the myrrh are combined together, and the Chinese medicinal composition of the invention is a monarch drug.

The cinnamon, the dried ginger and the cassia twig can assist monarch drugs to strengthen the effects of activating blood and relieving pain; pawpaw, lycopodium clavatum and pubescent angelica root are pungent in flavor and warm in property, stimulate the circulation of the blood and relax the muscles and joints, and relieve spasm and acute pain. The six medicines are used as ministerial medicines in the traditional Chinese medicine composition.

The cardamom, the angelica dahurica, the agastache and the clove all have pungent and warm properties, are pungent and warm and can promote qi circulation and warm spleen and stomach, and are used as adjuvant drugs in the traditional Chinese medicine composition.

The medicines are combined, and the effects of relieving symptoms and avoiding relapse are achieved by combining the warming effect, the medicine effect and the acupoint effect through moxibustion therapy and fumigation and ironing corresponding acupoints, and the three effects are not enough. If the composition is applied by other external drugs such as navel patch or acupoint patch, the warming effect is lacked, and the treatment effect is greatly reduced or even ineffective.

Preferably, the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 13-17 parts of wrinkled gianthyssop herb, 12-18 parts of frankincense, 7-11 parts of clove, 12-18 parts of myrrh, 7-12 parts of cinnamon, 13-16 parts of cassia twig, 10-13 parts of dried ginger, 14-16 parts of cardamom, 8-11 parts of pawpaw, 8-11 parts of radix angelicae pubescentis, 13-18 parts of angelica, 9-13 parts of radix angelicae and 9-13 parts of lycopodium clavatum.

Preferably, the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 15 parts of wrinkled gianthyssop herb, 15 parts of frankincense, 10 parts of clove, 15 parts of myrrh, 10 parts of cinnamon, 15 parts of cassia twig, 12 parts of dried ginger, 15 parts of cardamom, 9 parts of pawpaw, 9 parts of pubescent angelica root, 15 parts of Chinese angelica, 12 parts of dahurian angelica root and 12 parts of common clubmoss herb.

The embodiment of the invention also provides a preparation method of the traditional Chinese medicine composition for treating ulcerative colitis by cooperating with moxibustion, and the preparation method specifically comprises the following operations: weighing the raw materials according to the raw material proportion of the traditional Chinese medicine composition, mixing and crushing to obtain the traditional Chinese medicine composition.

The preparation method is simple, and the obtained powder can be placed in moxibustion box and applied to Shenque acupoint to rapidly relieve symptoms such as abdominal pain and diarrhea during UC attack.

Preferably, the particle size of the comminution is < 2 mm.

The embodiment of the invention also provides application of the traditional Chinese medicine composition for treating ulcerative colitis by cooperating with moxibustion therapy in preparing a moxibustion medicine for treating ulcerative colitis. After the traditional Chinese medicine composition is prepared into moxibustion medicine, the effect of relieving symptoms such as abdominal pain, diarrhea, mucopurulent bloody stool and the like during UC attack can be achieved by performing moxibustion on specific acupuncture points, the immunity function of a human body can be stimulated, the UC attack frequency is reduced, and the life quality of a patient is improved.

Preferably, the moxibustion medicine for treating ulcerative colitis is a medicine which is ignited and then fumigated and burned on Shenque, Guanyuan, Zusanli and Tianshu acupoints. The medicine is applied to each acupoint with the dosage of 20-ton (20 g) per time (based on the mass of the traditional Chinese medicine composition), each acupoint is subjected to moxibustion for 10 minutes, 14 days of moxibustion is 1 course of treatment, the treatment is stopped for 2 days after 1 course of treatment, the 2 nd course of treatment is continued, and the effects of relieving UC symptoms and reducing attack times can be achieved after 2 courses of moxibustion are performed.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

Example 1

The embodiment of the invention provides a traditional Chinese medicine composition for treating ulcerative colitis by matching moxibustion, which comprises the following raw materials in parts by weight:

15 parts of wrinkled gianthyssop herb, 15 parts of frankincense, 10 parts of clove, 15 parts of myrrh, 10 parts of cinnamon, 15 parts of cassia twig, 12 parts of dried ginger, 15 parts of cardamom, 9 parts of pawpaw, 9 parts of pubescent angelica root, 15 parts of Chinese angelica, 12 parts of dahurian angelica root and 12 parts of common clubmoss herb.

The preparation method comprises the following steps: weighing the raw materials according to the raw material proportion of the traditional Chinese medicine composition, mixing, and crushing the raw materials together by a traditional Chinese medicine crusher to obtain the traditional Chinese medicine composition.

When in use, the pulverized powder is placed in a moxibustion box, and moxibustion is carried out on Shenque point, Guanyuan point, Shuangzusanli point and Shuangtianshu point for 10 minutes at the dosage of 20 Zhuang (namely 20g) for each acupoint, and the dosage is 1 time per day.

Example 2

13 parts of wrinkled gianthyssop herb, 12 parts of frankincense, 7 parts of clove, 12 parts of myrrh, 7 parts of cinnamon, 13 parts of cassia twig, 10 parts of dried ginger, 14 parts of cardamom, 8 parts of pawpaw, 8 parts of pubescent angelica root, 13 parts of angelica, 9 parts of angelica dahurica and 9 parts of lycopodium clavatum.

The preparation method and the using method are the same as the example 1.

Example 3

17 parts of wrinkled gianthyssop herb, 18 parts of frankincense, 11 parts of clove, 18 parts of myrrh, 12 parts of cinnamon, 16 parts of cassia twig, 13 parts of dried ginger, 16 parts of cardamom, 11 parts of pawpaw, 11 parts of pubescent angelica root, 18 parts of Chinese angelica, 13 parts of angelica root and 13 parts of lycopodium clavatum.

The preparation method and the using method are the same as the example 1.

Example 4

10 parts of wrinkled gianthyssop herb, 9 parts of frankincense, 4 parts of clove, 9 parts of myrrh, 3 parts of cinnamon, 12 parts of cassia twig, 6 parts of dried ginger, 12 parts of cardamom, 6 parts of pawpaw, 6 parts of pubescent angelica root, 10 parts of Chinese angelica, 6 parts of angelica root and 6 parts of lycopodium clavatum.

The preparation method and the using method are the same as the example 1.

Example 5

20 parts of wrinkled gianthyssop herb, 20 parts of frankincense, 12 parts of clove, 20 parts of myrrh, 15 parts of cinnamon, 18 parts of cassia twig, 15 parts of dried ginger, 18 parts of cardamom, 12 parts of pawpaw, 15 parts of pubescent angelica root, 20 parts of angelica, 15 parts of angelica dahurica and 15 parts of lycopodium clavatum

The preparation method and the using method are the same as the example 1.

Comparative example 1

The comparative example provides a traditional Chinese medicine composition for treating ulcerative colitis by matching moxibustion therapy, on the basis of example 1, frankincense and myrrh are replaced by rhizoma corydalis with the efficacy of the two, and the traditional Chinese medicine composition specifically comprises the following raw materials in parts by weight:

15 parts of wrinkled gianthyssop herb, 30 parts of corydalis tuber, 10 parts of clove, 10 parts of cinnamon, 15 parts of cassia twig, 12 parts of dried ginger, 15 parts of round cardamom, 9 parts of pawpaw, 9 parts of pubescent angelica root, 15 parts of angelica, 12 parts of angelica dahurica and 12 parts of lycopodium clavatum.

The preparation method and the using method are the same as the example 1.

Comparative example 2

The comparative example provides a traditional Chinese medicine composition for treating ulcerative colitis by cooperating with moxibustion, and on the basis of example 1, cassia twig is replaced by asarum with similar efficacy, and the traditional Chinese medicine composition specifically comprises the following raw materials in parts by weight:

15 parts of wrinkled gianthyssop herb, 15 parts of frankincense, 10 parts of clove, 15 parts of myrrh, 10 parts of cinnamon, 15 parts of asarum, 12 parts of dried ginger, 15 parts of cardamom, 9 parts of pawpaw, 9 parts of pubescent angelica root, 15 parts of angelica, 12 parts of angelica dahurica and 12 parts of lycopodium clavatum.

The preparation method and the using method are the same as the example 1.

Effect example 1

The effect example provides animal test results of the traditional Chinese medicine composition for treating ulcerative colitis by combining moxibustion in examples 1-5 and comparative examples 1 and 2 of the invention, so as to investigate the influence of the traditional Chinese medicine composition on mucosal healing.

1. Test subjects: healthy SD rats, each half male and female, weighing 150 + -20 g, were randomly divided into 9 groups, blank control group, model group, examples 1-5 group, comparative example 1 group and comparative example 2 group. Each group of rats freely takes water 7d and has a circadian rhythm of 12h, the room temperature is 20 +/-2 ℃, and the relative humidity is 55-80%. And fasting is not forbidden 24h before molding.

2. The molding method comprises the following steps: after 24h of fasting, the patient is anesthetized, a catheter is inserted into the patient from the anus for about 8cm, 5% acetic acid solution is injected for 20s, and then normal saline is injected for flushing. Within 3d, rats all showed different degrees of bloody diarrhea, decreased appetite, dull hair, less movement, and weight loss. The success of molding is comprehensively judged by fecal occult blood and disease activity index scoring (shown in table 1), observation of colon tissue morphology by using a light mirror and an electron microscope. The blank control was not molded.

3. The treatment method comprises the following steps: referring to the animal acupuncture point atlas of Experimental acupuncture, the acupuncture points are simulated and positioned according to a comparative anatomical method, and the Shenque point, Guanyuan point, Zusanli point and Tianshu point are taken to remove hairs and serve as moxibustion parts.

The Chinese medicinal compositions of examples 1-5 and comparative examples 1-3 were placed in moxibustion boxes of each group, 0.36g in each moxibustion box, and subjected to moxibustion treatment on Shenque, Guanyuan, Zusanli and Tianshu acupoints 1 time a day for 10min each time after ignition.

The placebo and model groups were not treated.

4. Test results

The general condition and fecal condition of the rats were observed during the treatment period, and after 4 weeks of treatment, disease activity index scores were made according to table 1, with the results shown in table 2. Thereafter, the rats of each group were anesthetized, and colon tissues of the lesion site were taken for pathological observation.

TABLE 1 disease Activity index Scoring Table

Table 2 disease Activity index scores for groups of rats

Note: a: p is less than 0.05 when compared with an empty control group;

b: compared with the model group, p is less than 0.05.

The pathological observation results of colon tissues at the pathological parts of rats in each group are as follows:

the model group has colocele and edema, mucosal epithelium congestion, villus defect, obvious ulcer surface, irregular glandular structure, submucosal swelling and congestion, and a large amount of inflammatory cells infiltration;

in the embodiment, mucous epithelium of each group is basically complete without obvious ulcer, glands are complete and tidy, and inflammatory cell infiltration is not seen;

the colon condition of the group of the comparative example 1 is superior to that of the model group, but the mucous membrane villi are still defective, have ulcer surfaces, the arrangement of glands is irregular, and a small amount of inflammatory cell infiltration can be seen;

the colon condition of comparative example 2 was superior to that of the model group, but the mucocutaneous villi had few defects, had few ulcer surfaces, the glands were arranged in a somewhat regular manner, but a few inflammatory cells were still visible.

From the results, under the treatment mode of cooperating with moxibustion, the traditional Chinese medicine compositions provided by each group of the examples and each group of the comparative examples have the effect of relieving the UC symptom, but the traditional Chinese medicine composition provided by each group of the examples has the effect of relieving the UC symptom better than the traditional Chinese medicine compositions provided by the comparative examples 1 and 2, and can more effectively promote the intestinal mucosa to repair.

Effect example 2

The effect example provides the result of the statistics of the clinical application effect of the traditional Chinese medicine composition for treating ulcerative colitis by combining moxibustion in the embodiment 1 of the invention.

Counting objects: 2015-2020, 100 patients in an outpatient clinic and an inpatient clinic of department of traditional Chinese medicine of Hebei province are randomly selected from patients adopting the same conventional treatment mode, wherein 54 patients are combined with the traditional Chinese medicine composition provided by the invention in the embodiment 1 to be matched with moxibustion treatment, the 54 patients are accompanied by mucopurulent bloody stool, 52 patients have abdominal pain symptoms, 53 patients are accompanied by diarrhea, 46 patients without moxibustion are accompanied by mucopurulent bloody stool, 44 patients have abdominal pain symptoms, and 43 patients are accompanied by diarrhea.

After 1 month from the date of treatment, among 54 patients who used the combination of the traditional Chinese medicine composition provided in example 1 of the present invention and moxibustion therapy, 49 patients had a remission rate of mucopurulent bloody stool of 90.74%; among 52 cases with abdominal pain symptoms, 47 cases with abdominal pain are relieved, and the relieving rate is 90.38%; among 53 cases with diarrhea, 51 cases were relieved with a remission rate of 96.23%. Among 46 patients who did not undergo moxibustion, 38 patients had relieved mucopurulent bloody stool, with a remission rate of 86.36%; in 44 cases with abdominal pain symptoms, 38 cases of abdominal pain are relieved, and the relieving rate is 82.61%; of the 43 cases with diarrhea, 39 were relieved with a 90.70% remission rate. The results are shown in tables 3 and 4.

TABLE 3 clinical application Effect statistics in conjunction with moxibustion therapy

Symptoms and signs	Total number of people	Relief population	Percentage of remission
				Abdominal pain	52	47	90.38％
Mucous bloody stool	54	49	90.74％
				Diarrhea (diarrhea)	53	51	96.23％

TABLE 4 statistics of clinical application effect without moxibustion

Symptoms and signs	Total number of people	Relief population	Percentage of remission
				Abdominal pain	44	38	82.61％
Mucous bloody stool	46	38	86.36％
				Diarrhea (diarrhea)	43	39	90.70％

Effect example 3

The effect example provides an individual case of clinical application of the traditional Chinese medicine composition for treating ulcerative colitis by combining moxibustion in example 1 of the invention.

Case 1:

zhao, man, age 33, Hebei province, Baoding City, individual household. Patients are out of order day and night, tired excessively, irregular diet, and have a diagnosis of ulcerative colitis due to 'stomachache and hematochezia', and are treated with mesalazine enteric-coated tablets and hormones, but the patients relapse after stopping taking the medicine due to work tiredness and irregular diet, and work and life are affected. Then, the traditional Chinese medicine composition for treating ulcerative colitis in the embodiment 1 of the invention is used for moxibustion treatment on Shenque, Guanyuan, Zusanli and Tianshu for 15 days, and is used for treatment with western medicines, so that hematochezia is obviously reduced, abdominal pain is reduced, the western medicines are stopped after moxibustion treatment is continued for 2 months, the later patients have stable illness, and no recurrence is caused after 1 year of diagnosis.

Case 2

Sunzhi, female, 59 years old, Hebei province, Zhengxian county, farmer. Ulcerative colitis was diagnosed in 2011, and the disease is difficult to be cured by searching medicines. The traditional Chinese medicine composition for treating ulcerative colitis in the embodiment 1 of the invention is used for moxibustion treatment of Shenque, Guanyuan, Zusanli and Tianshu, and after 30 days, abdominal pain disappears, and stool is performed one row a day and has a normal color. After 6 months, no recurrence occurred.

Case 3:

zhang-a, male, 54 years old, Qiqi Haer City, Heilongjiang province, and officer. The ulcerative colitis of the patient can not be cured in 10 years by adopting various treatment methods such as Chinese and western medicines locally, and the recurrence is gradual, so that the Chinese medicinal composition for treating the ulcerative colitis by matching with moxibustion in the embodiment 1 of the invention is applied to moxibustion on Shenque, Guanyuan, Zusanli and Tianshu for 1 month in 2018, the symptoms are relieved, and the recurrence is not caused until the follow-up.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents or improvements made within the spirit and principle of the present invention should be included in the scope of the present invention.

Claims

1. A traditional Chinese medicine composition for treating ulcerative colitis in cooperation with moxibustion therapy is characterized in that: the composition is prepared from the following raw materials in parts by weight: 10-20 parts of wrinkled gianthyssop herb, 9-20 parts of frankincense, 4-12 parts of clove, 9-20 parts of myrrh, 3-15 parts of cinnamon, 12-18 parts of cassia twig, 6-15 parts of dried ginger, 12-18 parts of cardamom, 6-12 parts of pawpaw, 6-15 parts of radix angelicae pubescentis, 10-20 parts of angelica, 6-15 parts of radix angelicae and 6-15 parts of lycopodium clavatum; the traditional Chinese medicine composition is smoked on acupuncture points after being ignited.

2. The traditional Chinese medicine composition for treating ulcerative colitis with moxibustion therapy according to claim 1, is characterized in that: the composition is prepared from the following raw materials in parts by weight: 13-17 parts of wrinkled gianthyssop herb, 12-18 parts of frankincense, 7-11 parts of clove, 12-18 parts of myrrh, 7-12 parts of cinnamon, 13-16 parts of cassia twig, 10-13 parts of dried ginger, 14-16 parts of cardamom, 8-11 parts of pawpaw, 8-11 parts of radix angelicae pubescentis, 13-18 parts of angelica, 9-13 parts of radix angelicae and 9-13 parts of lycopodium clavatum.

3. The traditional Chinese medicine composition for treating ulcerative colitis with moxibustion therapy according to claim 2, is characterized in that: the composition is prepared from the following raw materials in parts by weight: 15 parts of wrinkled gianthyssop herb, 15 parts of frankincense, 10 parts of clove, 15 parts of myrrh, 10 parts of cinnamon, 15 parts of cassia twig, 12 parts of dried ginger, 15 parts of cardamom, 9 parts of pawpaw, 9 parts of pubescent angelica root, 15 parts of Chinese angelica, 12 parts of dahurian angelica root and 12 parts of common clubmoss herb.

4. A preparation method of a traditional Chinese medicine composition for treating ulcerative colitis in cooperation with moxibustion therapy is characterized by comprising the following operations: weighing the raw materials according to the proportion of the raw materials of the traditional Chinese medicine composition of any one of claims 1 to 3, mixing and then crushing.

5. The method for preparing the Chinese medicinal composition for treating ulcerative colitis with moxibustion therapy according to claim 4, wherein the particle size of the pulverized material is less than 2 mm.

6. The use of the Chinese medicinal composition for treating ulcerative colitis according to any one of claims 1 to 3 in combination with moxibustion in the preparation of a medicament for moxibustion treatment of ulcerative colitis.

7. The use of claim 6, wherein the moxibustion medicine for treating ulcerative colitis is a medicine which is smoked on Shenque, Guanyuan, Zusanli and Tianshu acupoints after ignition.