CN106377613A - Externally applied drug for treating psoriasis and preparation method thereof - Google Patents
Externally applied drug for treating psoriasis and preparation method thereof Download PDFInfo
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- CN106377613A CN106377613A CN201610901235.7A CN201610901235A CN106377613A CN 106377613 A CN106377613 A CN 106377613A CN 201610901235 A CN201610901235 A CN 201610901235A CN 106377613 A CN106377613 A CN 106377613A
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Abstract
The invention belongs to the field of traditional Chinese medicine preparations, and aims to provide an externally applied drug for treating psoriasis according to a psoriasis recognition mechanism in traditional Chinese medicine. The drug comprises the following components in parts by mass: 12-20g of Rumex japonicus Meisn, 12-20g of golden larch bark, 0.3-1g of chaulmoogra tree seed, 10-45g of radix rehmanniae, 2-5g of centipede, 0.06-0.18g of cantharis, 3-30g of rhubarb, 1-3g of calomel, 1-6g of white alum, 8-18g of toosendan fruit, 3-8g of pepper, 8-16g of kuh-seng, 8-16g of moutan bark, 3-12g of folium artemisiae argyi, 5-16g of fructus cnidii, 10-26g of Dittany Bark and 6-16g of erythrina bark. The drug provided by the invention is a favorable traditional Chinese medicine composition.
Description
Technical field
The invention belongs to field of traditional Chinese is and in particular to its one kind treats psoriasic external used medicine, particularly supply cattle
The field of the external used medicine that tinea patient uses and preparation method thereof.
Background technology
Psoriasiss are equivalent to the white scar of the traditional Chinese medical science, white shell skin ulcer, psoriasiss, psoriasis, stubborn dermatitis etc., are a kind of chronic inflammatory, non-sense
Metachromia dermatosiss.This disease, through slow, has tendency of recurrence.Its pathogenesis may with infection, dysbolismus, immunologic function,
The factor such as hereditary and its spiritual is relevant, but not yet illustrates completely so far, and the traditional Chinese medical science thinks that the generation of primary disease and heat in blood, blood be dry, blood stasis
Etc. relevant.Psoriatic's throughout world various places, different nationalities, sex, age all can fall ill.According to the literature, psoriasic
Sickness rate accounts for the 0.1%～3% of world population, and yellow's sickness rate is 0.1%～0.3%, sickness rate white race in crowd for this disease
People takes second place apparently higher than yellow, black race, and by the end of the end of the year 2000, China psoriatic increased one than 1994
Times；The prevalence in the north is higher than south again, and China psoriatic is at least 1,300,000～4,000,000 about.Psoriasiss can be divided into
Homeliness type, pustule type, arthropathica, erythrodermic, most commonly seen with homeliness type psoriasiss, clinical manifestation is with white squama, thin
Film phenomenon, petechial hemorrhage are characterized.Although psoriasiss do not threaten the life security of people, this disease because it is chronic, touching repeatedly,
Obstinate difficult more, high recurrence rate, have a strong impact on the social life of patient, cause great body and psychological misery, to patient
Physically and mentally healthy impact very big.Simultaneously as this sick recurrent exerbation, often need to repeatedly treat, also bring heavy economy to patient
Burden.
So, with regard to how to find one kind can the psoriasic medicine of effectively treatment, be our current problems in urgent need to solve.
Content of the invention
With the continuous development of China's Chinese medicine, in treatment psoriasiss, people gradually appreciate Chinese traditional treatment
Psoriasic advantage, and the advantage such as good effect, instant effect, toxic and side effects are little over the course for the treatment of, for existing western medical treatment cattle
The present situation of tinea, the purpose of the present invention is to be to provide one kind to treat psoriasic external used medicine, early to solve psoriatic
Day restorative problem.This medicine is with common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, can have
Effect treats above-mentioned psoriasiss.
For reaching the purpose of foregoing invention, the technical solution adopted in the present invention is：One kind is provided to treat psoriasic outer
With medicine and preparation method thereof it is characterised in that each component of described medicine and its mass parts are than as follows：
Radix Rumicis Crispi 12～20g, Cortex Pseudolariciss 12～20g, Semen Hydnocarpi 0.3～1g, Radix Rehmanniae 10～45g, Scolopendra 2～5g, Mylabris
0.06～0.18g, Radix Et Rhizoma Rhei 3～30g, Calomelass 1～3g, Alumen 1～6g, Fructus Toosendan 8～18g, Pericarpium Zanthoxyli 3～8g, Radix Sophorae Flavescentiss 8～16g,
Cortex Moutan 8～16g, Folium Artemisiae Argyi 3～12g, Fructus Cnidii 5～16g, Cortex Dictamni 10～26g, Cortex erythrinae 6～16g.
A kind of treat psoriasic external used medicine and preparation method thereof it is characterised in that each component of described medicine and
Its mass parts is than as follows：
Radix Rumicis Crispi 13～17g, Cortex Pseudolariciss 13～17g, Semen Hydnocarpi 0.4～0.8g, Radix Rehmanniae 12～40g, Scolopendra 3～4.5g,
Mylabris 0.08～0.16g, Radix Et Rhizoma Rhei 5～26g, Calomelass 1.5～2.5g, Alumen 2～5.5g, Fructus Toosendan 10～16g, Pericarpium Zanthoxyli 5～7g,
Radix Sophorae Flavescentiss 10～14g, Cortex Moutan 10～14g, Folium Artemisiae Argyi 5～11g, Fructus Cnidii 8～14g, Cortex Dictamni 11～23g, Cortex erythrinae 8～14g.
One kind treats psoriasic external used medicine and preparation method thereof it is characterised in that the medicine of described " preferred plan "
Each component and its mass parts than as follows：
Radix Rumicis Crispi 15g, Cortex Pseudolariciss 15g, Semen Hydnocarpi 0.6g, Radix Rehmanniae 35g, Scolopendra 4g, Mylabris 0.15g, Radix Et Rhizoma Rhei 23g, Calomelass
2.3g, Alumen 5g, Fructus Toosendan 14g, Pericarpium Zanthoxyli 6g, Radix Sophorae Flavescentiss 12g, Cortex Moutan 12g, Folium Artemisiae Argyi 10g, Fructus Cnidii 12g, Cortex Dictamni 20g, sea
Cortex paulowniae 12g.
One kind treats psoriasic external used medicine and preparation method thereof it is characterised in that methods described comprises the steps
It is prepared from：
A, above-mentioned raw materials Chinese medicine is picked impurity, dust and is dried after, more stand-by than being ground into coarse altogether according to mass parts；
B, the coarse crushing medicine is contained tying in cloth bag, the cloth bag tying mouth is placed with the medicine device of lid simultaneously
In, add the medicinal alcohol that concentration is 70～75% appropriate, Mi Gai stirs or shakes, and impregnates 125 hours, inclines after taking supernatant, then
Secondary add 70～75% ethanol appropriate, to be impregnated fully leach to effective ingredient after, pull the cloth bag containing medicine out, merge leaching
Go out liquid, stand 12 hours, filter and get product tincture dose medicament.
One kind treats psoriasic external used medicine and preparation method thereof it is characterised in that described using method is：By tincture
Final drug cotton swab is uniformly applied to site of disease, rubs 5～8 minutes, a day three times, the morning, noon and afternoon respectively apply ointment once, control simultaneously
Treat and can fully recover for 2～3 months.
Each raw material Chinese medicine in prescription of the present invention all has detailed in Chinese Pharmacopoeia, Chinese dictionary and its China's book on Chinese herbal medicine
Record.It is raw material that the present invention selects most common of which Chinese medicine, gives full play to the pharmacological effect of each component：
Radix Rumicis Crispi, nature and flavor：Bitter in the mouth, acid, cold in nature（Cool）, slightly poisonous, there is dampness removing, Huang is moved back in function of gallbladder promoting, detumescence, spleen benefiting and stimulating the appetite, pathogenic fire purging,
The effect of expelling pathogenic heat to loosen the bowels, antibacterial, for treating acute hepatitises, chronic tracheitiss, lung-heat hemoptysis, haematemesis, epistaxis, hemorrhoidal bleeding, function
Property metrorrhagia, leucopaenia purpura disease, big constipation, dermatosiss, anal inflammation, innominate toxic swelling, stranguria with turbid discharge, jaundice, carbuncle, head
Louse white scales, scabies, stubborn dermatitis；
Cortex Pseudolariciss, nature and flavor：Pungent, warm, poisonous, there is the effect of expelling wind and removing dampness, killing parasites for relieving itching, for treating scabies, eczema, nerve
Property multiple tinea such as dermatitis, tinea corporis, tinea manus and pedis, tinea capitis card；
Semen Hydnocarpi, nature and flavor：Acrid in the mouth, property heat, very toxic, there is the effect of dispeiling pathogenic wind and removing dampness, detoxicating and killing parasites, belong to killing parasites for relieving itching medicine,
Clinical main sick with controlling lepromatous leprosy；
Radix Rehmanniae, nature and flavor：Sweet in the mouth, hardship, cold in nature, there is the effect of heat clearing away, removing heat from blood, join the army blood, high fever for treatment warm febrile disease
Coma, xerostomia crimson tongue；
Scolopendra, nature and flavor：Pungent, warm, poisonous, there is the effect of wind-dispelling, arresting convulsion, counteracting toxic substances, eliminating stagnation, for treating apoplexy, infantile convulsion, broken wound
Wind, pertussis, scrofula, tuberculosis, disease buildup block, sore swollen toxin, tinea corporis, the in vain bald, disease such as anal fistula, scald；
Mylabris, nature and flavor：Pungent, hot, very toxic, have removing blood stasis disappear, work(poison phagedenoma, the effect of draw red foaming, for treating abdominal mass
Lump, for many years stubborn dermatitis, scrofula, wart, carbuncle are not burst, the dead flesh of malignant boil；
Radix Et Rhizoma Rhei, nature and flavor：Bitter, cold, have removing the relative excess heat, removing mass is stagnant, clots absorbing blood the effect of, for treating excess-heat constipation, food stagnation is stagnated,
Stomachache, acute appendicitiss, acute infectious hepatitis, blood stasis is through closing, toothache, epistaxis, acute conjunctivitiss, burn and scald, change are controlled in external
The diseases such as purulence dermatosiss, carbuncle swells sore；
Calomelass, nature and flavor：Pungent, cold, poisonous, have parasite killing, counteracting toxic substances, putrefaction removing, antipruritic, eliminating the phlegm, relieve oedema or abdominal distension through diuresis or purgation, relieving constipation the effect of, be used for controlling
Treat that skin infection festers, scabies prurigo, scrofula, syphilis, chancre, wine nose, acne, anxious chronic infantile convulsion, expectorant stop up dyspnea, oedema turgor, two
Just the disease such as unfavorable；
Alumen, nature and flavor：Sour and astringent, cold, poisonous, there is eliminating the phlegm dampness, the effect of removing toxic substances parasite killing, antidiarrheal are stopped blooding, for treat apoplexy,
Epilepsy, sore throat, scabies eczema, swollen ulcer drug, burn due to hot liquid or fire, aphtha of the mouth and tongue, marginal blepharitiss eye, discharging ear, polyp, skin ulcer hemorrhoid in nose
Pain, metrorrhagia, epistaxis, bleeding due to trauma, chronic diarrhea nine dysentery, leukorrhagia pudendal pruritus, proctoptosis, uterine prolapse；
Fructus Toosendan, nature and flavor：Bitter, cold, poisonous, the effect of having except damp and hot, clearing away liver-fire, pain relieving, parasite killing, for treating the cold limbs due to intense heat in the interior heart
Bitterly, hypochondriac pain, colic, abdominal pain due to worm stagnation；
Pericarpium Zanthoxyli, nature and flavor：Pungent, warm, poisonous, there is the effect of warming spleen and stomach for dispelling cold, dehumidifying, pain relieving, parasite killing, solution fish raw meat poison, for treating
Food stagnation stop drink, trusted subordinate's crymodynia, vomiting, oh, cough with dyspnea, anemofrigid-damp arthralgia, have loose bowels, dysentery, colic, toothache, ascariasis, pinworm
The diseases such as disease, pudendal pruritus, sore scabies；
Radix Sophorae Flavescentiss, nature and flavor：Bitter, cold, there is the effect of heat clearing away, dampness, parasite killing, for treat toxic-heat and blood stasis, discharging fresh blood stool, jaundice,
Leucorrhea with red and white discharge, infantile pneumonia, infantile malnutrition, acute tonsillitiss, anal fistula, proctoptosis, skin pruritus, mange malignant boil, erosion of vulva pruritus due to damp pathogen, scrofula
Scrofula, scald, external treatment trichomonal vaginitis；
Cortex Moutan, nature and flavor：Arduous, cool, there is the effect of heat clearing away, removing heat from blood and blood, repercussive, for treat the pathogenic heat attacking blood system in febrile diseases, send out speckle,
Infantile convulsion, tell, be defeated in battle, having blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea, lump in the abdomen, carbuncle and ulcer, flutterring the diseases such as damage；
Folium Artemisiae Argyi, nature and flavor：Acrid, bitter, warm, slightly poisonous, there is the effect of dispersing cold for relieving pain, warming the meridian for stopping bleeding, for treating few abdomen crymodynia, warp
Cold uncomfortable, uterus cold infertile, haematemesis, epistaxis, metrorrhagia, through many, gestation hemorrhage, external treatment skin pruritus, vinegar Chinese mugwort charcoal warming the meridian for stopping bleeding, are used for
Deficient cold type bleeding；
Fructus Cnidii, nature and flavor：Arduous, warm, there is the effect of warming the kidney to activate YANG, wind-dispelling, dampness, parasite killing, for treating impotence in male, the moon
Capsule pruritus due to damp pathogen, woman's leukorrhagia pudendal pruritus, cold uterus are infertile, the disease such as rheumatic arthralgia, scabies eczema；
Cortex Dictamni, nature and flavor：Bitter salty, cold, there is wind-dispelling, dampness, heat clearing away, merit of removing toxic substances effect, for treat wind heat sore, scabies,
Itchy skin eruption, rheumatic arthralgia, jaundice；
Cortex erythrinae, nature and flavor：Bitter, pungent, flat, there is the effect of expelling wind and removing dampness, channels sootheing and network vessel quickening, killing parasites for relieving itching, for treating rheumatism numbness
Bitterly, the disease such as podomere contracture, traumatic injury, scabies, eczema.
Medicine of the present invention is based on the psoriasic principle of Chinese traditional treatment, thinks from pharmacological action and its mechanism of action：With regard to cattle
Tinea, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good therapeutic effect to above-mentioned disease.
Specific embodiment
A kind of Chinese medicine formula that the present invention is aiming at above-mentioned psoriasis treatment and proposes, using the medicine of this formula preparation
Thing good drug efficacy, instant effect, it is the Chinese prescription of a treating both the principal and secondary aspects of a disease, be particularly suitable for Clinical practice.Tool with reference to the present invention
Body embodiment is described in further detail：
Embodiment 1：
A kind of treat psoriasic external used medicine it is characterised in that each component of described medicine and its mass parts are than following institute
Show：
Radix Rumicis Crispi 15g, Cortex Pseudolariciss 15g, Semen Hydnocarpi 0.6g, Radix Rehmanniae 35g, Scolopendra 4g, Mylabris 0.15g, Radix Et Rhizoma Rhei 23g, Calomelass
2.3g, Alumen 5g, Fructus Toosendan 14g, Pericarpium Zanthoxyli 6g, Radix Sophorae Flavescentiss 12g, Cortex Moutan 12g, Folium Artemisiae Argyi 10g, Fructus Cnidii 12g, Cortex Dictamni 20g, sea
Cortex paulowniae 12g.Embodiment 2：
A kind of treat psoriasic external used medicine it is characterised in that each component of described medicine and its mass parts are than following institute
Show：
Radix Rumicis Crispi 17g, Cortex Pseudolariciss 17g, Semen Hydnocarpi 0.8g, Radix Rehmanniae 40g, Scolopendra 4.5g, Mylabris 0.16g, Radix Et Rhizoma Rhei 26g, light
Powder 2.5g, Alumen 5.5g, Fructus Toosendan 16g, Pericarpium Zanthoxyli 7g, Radix Sophorae Flavescentiss 14g, Cortex Moutan 14g, Folium Artemisiae Argyi 11g, Fructus Cnidii 14g, Cortex Dictamni
23g, Cortex erythrinae 14g.
Embodiment 3：
A kind of treat psoriasic external used medicine it is characterised in that each component of described medicine and its mass parts are than following institute
Show：
Radix Rumicis Crispi 20g, Cortex Pseudolariciss 20g, Semen Hydnocarpi 1g, Radix Rehmanniae 45g, Scolopendra 5g, Mylabris 0.18g, Radix Et Rhizoma Rhei 30g, Calomelass 3g,
Alumen 6g, Fructus Toosendan 18g, Pericarpium Zanthoxyli 8g, Radix Sophorae Flavescentiss 16g, Cortex Moutan 16g, Folium Artemisiae Argyi 12g, Fructus Cnidii 16g, Cortex Dictamni 26g, Cortex erythrinae
16g.
Model case
Through clinical conditions psoriatic totally 605, the age is 305 of more than 20 years old, only 300 be 20 years old with
Under.580 of recovery from illness in 605 patients, effective 23, total effective rate reaches 100%.
Claims (3)
1. a kind of treat psoriasic external used medicine it is characterised in that each component of described medicine and its mass parts ratio are as follows
Shown：
Radix Rumicis Crispi 12～20g, Cortex Pseudolariciss 12～20g, Semen Hydnocarpi 0.3～1g, Radix Rehmanniae 10～45g, Scolopendra 2～5g, Mylabris
0.06～0.18g, Radix Et Rhizoma Rhei 3～30g, Calomelass 1～3g, Alumen 1～6g, Fructus Toosendan 8～18g, Pericarpium Zanthoxyli 3～8g, Radix Sophorae Flavescentiss 8～16g,
Cortex Moutan 8～16g, Folium Artemisiae Argyi 3～12g, Fructus Cnidii 5～16g, Cortex Dictamni 10～26g, Cortex erythrinae 6～16g.
2. according to claim 1 treatment psoriasic external used medicine it is characterised in that each component of described medicine and
Its mass parts is than as follows：
Radix Rumicis Crispi 13～17g, Cortex Pseudolariciss 13～17g, Semen Hydnocarpi 0.4～0.8g, Radix Rehmanniae 12～40g, Scolopendra 3～4.5g,
Mylabris 0.08～0.16g, Radix Et Rhizoma Rhei 5～26g, Calomelass 1.5～2.5g, Alumen 2～5.5g, Fructus Toosendan 10～16g, Pericarpium Zanthoxyli 5～7g,
Radix Sophorae Flavescentiss 10～14g, Cortex Moutan 10～14g, Folium Artemisiae Argyi 5～11g, Fructus Cnidii 8～14g, Cortex Dictamni 11～23g, Cortex erythrinae 8～14g.
3. treat psoriasic external used medicine it is characterised in that each group of described medicine according to claim 1 to 2
Divide and its mass parts are than as follows：
Radix Rumicis Crispi 15g, Cortex Pseudolariciss 15g, Semen Hydnocarpi 0.6g, Radix Rehmanniae 35g, Scolopendra 4g, Mylabris 0.15g, Radix Et Rhizoma Rhei 23g, Calomelass
2.3g, Alumen 5g, Fructus Toosendan 14g, Pericarpium Zanthoxyli 6g, Radix Sophorae Flavescentiss 12g, Cortex Moutan 12g, Folium Artemisiae Argyi 10g, Fructus Cnidii 12g, Cortex Dictamni 20g, sea
Cortex paulowniae 12g.
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| CN108310325A (en) * | 2018-04-17 | 2018-07-24 | 库伦旗保力尔蒙药材有限公司 | A kind of antipsoriatics object component and preparation method thereof |
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| CN101623373A (en) * | 2009-08-14 | 2010-01-13 | 周大红 | Traditional Chinese medicine composition for treating psoriasis and preparation method thereof |
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| CN101623373A (en) * | 2009-08-14 | 2010-01-13 | 周大红 | Traditional Chinese medicine composition for treating psoriasis and preparation method thereof |
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| CN108310325A (en) * | 2018-04-17 | 2018-07-24 | 库伦旗保力尔蒙药材有限公司 | A kind of antipsoriatics object component and preparation method thereof |
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