CN111658714A

CN111658714A - Traditional Chinese medicine composition for relieving itching and diminishing swelling after mosquito bites

Info

Publication number: CN111658714A
Application number: CN202010502233.7A
Authority: CN
Inventors: 张炳强; 陈梦梦
Original assignee: Qingdao Re Store Biotechnology Co ltd
Current assignee: Qingdao Re Store Biotechnology Co ltd
Priority date: 2020-06-04
Filing date: 2020-06-04
Publication date: 2020-09-15

Abstract

The invention discloses a traditional Chinese medicine composition for relieving itching and diminishing swelling after mosquito bites, which is prepared by extracting the following raw material medicines in parts by weight: 20-60 parts of folium artemisiae argyi, 20-60 parts of radix sophorae flavescentis, 20-60 parts of cortex phellodendri, 20-60 parts of mint, 20-60 parts of divaricate saposhnikovia root, 10-20 parts of pseudolarix, 10-20 parts of honeysuckle, 5-10 parts of camphor, 5-10 parts of borneol, 5-10 parts of dayflower, 5-10 parts of sculellaria barbata, 1-5 parts of antifebrile dichroa, 1-5 parts of rhizoma atractylodis, 1-5 parts of globe amaranth herb, 1-5 parts of melastoma dodecandrum root, 1-5 parts of valerian, 1-5 parts of earthworm, 1-5 parts of semen raphani, 1-5 parts of rhizoma acori graminei, 1-2 parts of semen brassicae and 1-2. The traditional Chinese medicine composition provided by the invention is scientific in formula, free of toxic and side effects, and strong in pertinence due to the use of a pure natural formula. The traditional Chinese medicine composition has the obvious effective rate of 96 percent for treating mosquito bites, can eliminate the symptoms of pruritus and thermalgia caused by the mosquito bites after being smeared for 1 minute on average, can eliminate red and swollen in 5 minutes at the fastest speed, and has reliable and quick curative effect. Can be used by adults and children, and is safe and reliable.

Description

Traditional Chinese medicine composition for relieving itching and diminishing swelling after mosquito bites

Technical Field

The invention relates to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for relieving itching and diminishing swelling after mosquito bites.

Background

In summer, mosquitoes are too heavily, and people often suffer from mosquito bites. Mosquito dermatitis is allergic dermatitis caused by mosquito bites, and is the main type of insect dermatitis. Mosquitoes stab the skin through the mouth organ, saliva or venom of the mosquitoes invades the skin, and after entering the skin of a human body, the mosquitoes cause inflammatory reaction, and serious reactions such as red swelling, hot pain, pruritus, local bullous generation, hemorrhagic necrosis and the like of individual people occur. Therefore, solving various skin itch and red swelling caused by mosquito bites is the key point for preventing and treating summer diseases.

The current research on itch shows that the conduction pathways of itch comprise histamine-dependent itch and non-histamine-dependent itch, and western medicine clinical treatment is mostly used for resisting histamine and diminishing inflammation and relieving pain aiming at the itch, but the medicines are mostly chemical compositions, generally have the defects of intolerance, easy generation of body drug resistance, inconvenient use, damage to skin caused by long-term use, such as pigmentation, allergy and other symptoms, and increase the burden of patients.

Various toilet waters for mosquito bites in the current market are prepared from traditional raw materials including anophelifuge, alcohol, menthol, borneol, thymol, camphor, essence, alcohol and deionized water, and the toilet water not only has the functions of cooling and removing miliaria, but also has poor effect on dermatitis caused by mosquito bites. And the anophelifuge contained in the floral water has certain toxicity, and in the using process, people absorb part of the anophelifuge through the digestive tract and the respiratory tract, so that the floral water not only can induce diseases such as asthma, but also can cause cancer and teratogenesis after long-term use. Some toilet water is usually added with salicylic acid compounds to achieve anti-inflammatory effect, but the salicylic acid compounds have high permeability, so that the toilet water not only can irritate the skin, but also can dry the skin. In addition, many toilet waters containing menthol often trigger a stress response in the human skin.

Comparing files: a Chinese medicinal composition, preparation, floral water and its application method (patent application No. 201210315409.3) are disclosed, a Chinese medicinal composition for repelling mosquito and relieving itching is prepared from Saviae Miltiorrhizae radix, herba Menthae, calculus bovis, stigma croci Sativi, flos Lonicerae, flos Chrysanthemi Indici, cortex Dictamni Radicis, radix astragali, flos Caryophylli, radix Sophorae Flavescentis, flos Campsis, and herba Portulacae, and can be used for treating mosquito and insect bite with the effects of relieving itching in 8 minutes, relieving swelling in 1 day, and prolonging itching relieving and swelling time. Comparing files: a Chinese medicinal composition for relieving itching and swelling after mosquito bites and a preparation method thereof (patent application number: 201610700793.7), the invention discloses a Chinese medicinal composition for relieving itching and swelling after mosquito bites, which consists of astragalus, bezoar, barbed skullcap herb, liquorice, belvedere fruit, lightyellow sophora root, cinnamon and clove, the itching and heat pain symptoms caused by mosquito bites can be eliminated by applying the Chinese medicinal composition for 5 minutes on average, the redness and swelling can be eliminated in 30 minutes, and the itching and swelling relieving time is longer. Therefore, it is necessary to invent a traditional Chinese medicine composition with better detumescence and itching relieving effects.

Disclosure of Invention

The invention aims to solve the defects of the prior art and provides a traditional Chinese medicine composition for efficiently and safely relieving swelling and itching caused by mosquito bites. The formula is prepared by screening medicinal flavors through a large number of experiments on the basis of the prior art, and selecting folium artemisiae argyi, radix sophorae flavescentis, cortex phellodendri, mint, radix sileris, cortex pseudolaricis, honeysuckle, camphor, borneol, dayflower, barbed skullcap herb, antifebrile dichroa, rhizoma atractylodis, globe amaranth, melastoma dodecandrum root, valerian, earthworm, radish seed, rhizoma acori graminei, mustard seed and cinnamomum burmanni root as raw materials. Folium Artemisiae Argyi can be used topically for eliminating dampness and relieving itching. Kuh-seng clears heat and dries dampness, kills parasites and induces diuresis. Cortex Phellodendri has effects of clearing heat, eliminating dampness, purging pathogenic fire, removing steam, removing toxic substance, and treating sore. Mint is one of the common Chinese traditional medicines, is a pungent and cool sweating and antipyretic medicine, and can be used for treating neuralgia, skin pruritus, rash, eczema and the like when being externally used. Ledebouriella root, radix Saposhnikoviae has the effects of relieving exterior syndrome, inducing perspiration, dispelling pathogenic wind, and removing dampness. Cortex pseudolaricis has effects of dispelling pathogenic wind, removing dampness, killing parasites and relieving itching. Honeysuckle flower, flos Lonicerae, for clearing away heat and toxic material, diminishing inflammation and relieving swelling. The camphor has the effects of dredging orifices, benefiting qi stagnation, removing dirt, killing parasites, relieving itching, reducing swelling and relieving pain. The borneol has the effects of inducing resuscitation, refreshing mind, clearing heat and removing toxicity. Commelina communis can clear heat, detoxify and induce diuresis. The barbed skullcap herb has the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, relieving swelling and pain and resisting cancer. Chang shan, the action is mild after wine processing, and the toxicity is reduced. Cang Zhu is indicated for damp obstruction of middle energizer, abdominal distention, diarrhea and edema. Qian Ri hong, clearing liver and improving vision, and removing toxicity. Melastoma dodecandrum root, Melastoma dodecandrum lour, radix Melastomatis Dodecandri, promotes blood circulation, stops bleeding, promotes diuresis, and removes toxic substance. Valerian root, rhizoma et radix Valerianae has effects of tranquilizing, expelling pathogenic wind, relieving spasm, promoting granulation, stopping bleeding, and relieving pain. Earthworm has the effects of clearing heat, arresting convulsion and dredging collaterals, and the earthworm can be crisp in texture and detoxified by being processed with wine. Radish seed, semen raphani, is used for food stagnation, abdominal distension and pain, constipation, food stagnation, diarrhea and dysentery, phlegm accumulation and cough and dyspnea. Shi Pu is indicated for abscess, swelling, back and traumatic injury. Mustard seed, semen Brassicae Junceae, dispersing pathogen accumulation, dredging collaterals and relieving pain. Yin Xiang Gen can warm the middle energizer, move qi and alleviate pain. The whole formula is a scientific formula based on the traditional Chinese medicine theory, and is not a simple combination of efficacy and flavor.

The invention is realized by adopting the following technical scheme:

a traditional Chinese medicine composition for relieving itching and diminishing swelling after mosquito bites is prepared by extracting the following raw material medicines in parts by weight: 20-60 parts of folium artemisiae argyi, 20-60 parts of radix sophorae flavescentis, 20-60 parts of cortex phellodendri, 20-60 parts of mint, 20-60 parts of divaricate saposhnikovia root, 10-20 parts of pseudolarix, 10-20 parts of honeysuckle, 5-10 parts of camphor, 5-10 parts of borneol, 5-10 parts of dayflower, 5-10 parts of sculellaria barbata, 1-5 parts of antifebrile dichroa, 1-5 parts of rhizoma atractylodis, 1-5 parts of globe amaranth herb, 1-5 parts of melastoma dodecandrum root, 1-5 parts of valerian, 1-5 parts of earthworm, 1-5 parts of semen raphani, 1-5 parts of rhizoma acori graminei, 1-2 parts of semen brassicae and 1-2.

Preferably, the traditional Chinese medicine composition for relieving itching and diminishing swelling after mosquito bites is prepared by extracting the following raw material medicines in parts by weight: 40 parts of folium artemisiae argyi, 40 parts of radix sophorae flavescentis, 40 parts of cortex phellodendri, 40 parts of mint, 40 parts of radix saposhnikoviae, 10 parts of cortex pseudolaricis, 10 parts of honeysuckle, 5 parts of camphor, 5 parts of borneol, 5 parts of dayflower, 5 parts of sculellaria barbata, 2 parts of antifebrile dichroa, 2 parts of rhizoma atractylodis, 2 parts of globe amaranth, 2 parts of melastoma dodecandrum root, 2 parts of valerian, 2 parts of earthworm, 2 parts of semen raphani, 2 parts of rhizoma acori graminei, 1 part of semen brassicae and 1 part of cinnamo.

A Chinese medicinal composition for relieving itching and swelling after mosquito bite is prepared by the following steps: the raw materials of the traditional Chinese medicine are respectively ground into powder according to the parts by weight, the powder is put into a container, medical alcohol is poured into the container, the container is sealed and soaked for not less than 2 weeks, and the finished product of the liquid medicine is obtained after filter residue is filtered. Respectively filling into packaging bottles, and sealing for storage.

The present invention relates to a medical alcohol extraction agent, and its internal soluble substance is brown semitransparent solution for curing bite of various toxic pests. When in use, the ointment is uniformly applied to the affected part, and has the effects of immediately relieving itching, relieving pain, activating blood circulation, reducing swelling and the like. The traditional Chinese medicine composition provided by the invention is scientific in formula, free of toxic and side effects, and strong in pertinence due to the use of a pure natural formula. The traditional Chinese medicine composition has the obvious effective rate of 96 percent for treating mosquito bites, can eliminate the symptoms of pruritus and thermalgia caused by the mosquito bites after being smeared for 1 minute on average, can eliminate red and swollen in 5 minutes at the fastest speed, and has reliable and quick curative effect. Can be used by adults and children, and is safe and reliable.

Detailed Description

The invention will be further elucidated with reference to the following specific examples.

Example 1

A traditional Chinese medicine composition for relieving itching and diminishing swelling after mosquito bites is prepared by extracting the following raw material medicines in parts by weight: 40 parts of folium artemisiae argyi, 40 parts of radix sophorae flavescentis, 40 parts of cortex phellodendri, 40 parts of mint, 40 parts of radix saposhnikoviae, 10 parts of cortex pseudolaricis, 10 parts of honeysuckle, 5 parts of camphor, 5 parts of borneol, 5 parts of dayflower, 5 parts of sculellaria barbata, 2 parts of antifebrile dichroa, 2 parts of rhizoma atractylodis, 2 parts of globe amaranth, 2 parts of melastoma dodecandrum root, 2 parts of valerian, 2 parts of earthworm, 2 parts of semen raphani, 2 parts of rhizoma acori graminei, 1 part of semen brassicae and 1 part of cinnamo.

The preparation method comprises the following steps: the raw materials of the traditional Chinese medicine are respectively ground into powder according to the weight parts, the powder is put into a container, medical alcohol is poured into the container, the container is sealed and soaked for not less than 2 weeks, and the finished product of the liquid medicine is obtained after filter residue is filtered. Respectively filling into packaging bottles, and sealing for storage.

When in use, the ointment is uniformly applied to the affected part, and has the effects of immediately relieving itching, relieving pain, activating blood circulation, reducing swelling and the like.

Example 2

A traditional Chinese medicine composition for relieving itching and diminishing swelling after mosquito bites is prepared by extracting the following raw material medicines in parts by weight: 60 parts of folium artemisiae argyi, 60 parts of radix sophorae flavescentis, 60 parts of cortex phellodendri, 60 parts of mint, 60 parts of radix saposhnikoviae, 10 parts of cortex pseudolaricis, 10 parts of honeysuckle, 10 parts of camphor, 10 parts of borneol, 10 parts of dayflower, 10 parts of sculellaria barbata, 1 part of antifebrile dichroa, 1 part of rhizoma atractylodis, 1 part of globe amaranth, 1 part of melastoma dodecandrum root, 1 part of valerian, 1 part of earthworm, 1 part of semen raphani, 1 part of rhizoma acori graminei, 1 part of semen brassicae and 1 part of cinnamo.

Example 3

A traditional Chinese medicine composition for relieving itching and diminishing swelling after mosquito bites is prepared by extracting the following raw material medicines in parts by weight: 20 parts of folium artemisiae argyi, 20 parts of radix sophorae flavescentis, 20 parts of cortex phellodendri, 20 parts of mint, 20 parts of radix saposhnikoviae, 10 parts of cortex pseudolaricis, 10 parts of honeysuckle, 10 parts of camphor, 10 parts of borneol, 10 parts of dayflower, 10 parts of sculellaria barbata, 1 part of antifebrile dichroa, 1 part of rhizoma atractylodis, 1 part of globe amaranth, 1 part of melastoma dodecandrum root, 1 part of valerian, 1 part of earthworm, 1 part of semen raphani, 1 part of rhizoma acori graminei, 1 part of semen brassicae and 1 part of cinnamo.

Example 4

Animal irritation test, allergy test: after 20 mice had their backs unhaired, the finished drug solutions prepared in example 1 of the present invention were applied to the unhaired parts and the unhatched parts, respectively, and no irritation or allergic reaction phenomena such as redness, rash, blister occurred after 30min, were observed.

Example 5

Selecting 50 subjects bitten by mosquitoes, wherein 5-10 years old and 8 persons are selected; 9 persons 11-20 years old; 14 people between 21-35 years old; 11 persons 35-55 years old; 8 people over 55 years old. The finished drug solution prepared in example 1 was sprayed on the bitten area to examine the onset time and the curative effect.

The evaluation standard of the curative effect is as follows:

remarkably: can quickly relieve itching and eliminate skin red swelling;

in general: can relieve itching and pain, and relieve skin red swelling;

and (4) invalidation: the effects of relieving itching and eliminating red swelling are not obvious.

The experimental results are as follows: the product is not seen in redness, rash and blister in all subjects. The symptoms of pruritus and thermalgia caused by mosquito bites can be eliminated by applying the ointment to a subject for 1 minute on average, and redness and swelling can be eliminated in 5 minutes at the fastest speed, so that the curative effect is reliable and quick. As shown in table 1, the significant effective rate of the present invention for treating mosquito bites is 96%.

TABLE 1 results of mosquito bites

	Antipruritic effect			Detumescence effect
						Is remarkable in that	In general	Invalidation	Is remarkable in that	In general	Invalidation
49	1	0	48	2	0

Example 6

Typical cases

1. Somebody in Han, woman, 56 years old. Before the product is not used, after the product is bitten by mosquitoes, symptoms such as swelling, pruritus and the like can appear at the bitten part, the pruritus is difficult to endure and cannot be held by the scratching part, and the swelling and swelling can be gradually subsided after two days. The finished liquid medicine prepared in the invention in the example 1 is used immediately after the mosquito bites, the pruritus is eliminated immediately, and the red swelling and the bulge are not generated. Can be carried about and used for a plurality of times, and has remarkable curative effects of relieving itching and detumescence.

2. Zhangzhi, male, 50 years old. The finished liquid medicine prepared in the invention in example 1 is used 30 minutes after the mosquito bites, and the pruritus disappears after 1 minute, and the red swelling and the bulge disappear after 10 minutes. After being used for a plurality of times, the swelling-diminishing and itching-relieving curative effect is obvious.

3. Old certain, woman, age 38. Before the product is not used, after the mosquito bites the product, symptoms such as red swelling, pruritus and the like appear at the bite part, the red swelling area is large, and the symptoms gradually disappear after 3 days. The finished liquid medicine prepared in the embodiment 1 of the invention is used 20 minutes after the mosquito bites, the pruritus disappears after less than 1 minute, and the red swelling disappears after 8 minutes of swelling. After being used for a plurality of times, the swelling-diminishing and itching-relieving curative effect is obvious.

4. Zhangzhi, male, age 8. The finished liquid medicine prepared in the embodiment 1 of the invention is used 10 minutes after the mosquito bites, the pruritus disappears after less than 1 minute, and the red swelling disappears after 5 minutes of swelling. Can be carried about and used for a plurality of times, and has remarkable curative effects of relieving itching and detumescence.

The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.

Claims

1. A traditional Chinese medicine composition for relieving itching and diminishing swelling after mosquito bites is characterized by being prepared by extracting the following raw material medicines in parts by weight: 20-60 parts of folium artemisiae argyi, 20-60 parts of radix sophorae flavescentis, 20-60 parts of cortex phellodendri, 20-60 parts of mint, 20-60 parts of divaricate saposhnikovia root, 10-20 parts of pseudolarix, 10-20 parts of honeysuckle, 5-10 parts of camphor, 5-10 parts of borneol, 5-10 parts of dayflower, 5-10 parts of sculellaria barbata, 1-5 parts of antifebrile dichroa, 1-5 parts of rhizoma atractylodis, 1-5 parts of globe amaranth herb, 1-5 parts of melastoma dodecandrum root, 1-5 parts of valerian, 1-5 parts of earthworm, 1-5 parts of semen raphani, 1-5 parts of rhizoma acori graminei, 1-2 parts of semen brassicae and 1-2.

2. The traditional Chinese medicine composition for relieving itching and diminishing swelling after mosquito bites according to claim 1 is characterized by being prepared by extracting the following raw material medicines in parts by weight: 40 parts of folium artemisiae argyi, 40 parts of radix sophorae flavescentis, 40 parts of cortex phellodendri, 40 parts of mint, 40 parts of radix saposhnikoviae, 10 parts of cortex pseudolaricis, 10 parts of honeysuckle, 5 parts of camphor, 5 parts of borneol, 5 parts of dayflower, 5 parts of sculellaria barbata, 2 parts of antifebrile dichroa, 2 parts of rhizoma atractylodis, 2 parts of globe amaranth, 2 parts of melastoma dodecandrum root, 2 parts of valerian, 2 parts of earthworm, 2 parts of semen raphani, 2 parts of rhizoma acori graminei, 1 part of semen brassicae and 1 part of cinnamo.

3. The traditional Chinese medicine composition for relieving itching and swelling after mosquito bites according to claim 1, which is prepared by the following steps: the raw materials of the traditional Chinese medicine are respectively ground into powder according to the parts by weight, the powder is put into a container, medical alcohol is poured into the container, the container is sealed and soaked for not less than 2 weeks, and the finished product of the liquid medicine is obtained after filter residue is filtered.