CN111630068A - 抗cd47抗体及其用途 - Google Patents
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
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Abstract
本发明涉及特异性结合整联蛋白相关蛋白(IAP),(也称为CD47)的新型抗体和抗体片段以及含有所述抗体或抗体片段的组合物。本发明还涉及编码所述抗体或其抗体片段的核酸及包含其的宿主细胞,以及相关用途。此外,本发明也涉及这些抗体和抗体片段的治疗和诊断用途。
Description
PCT国内申请,说明书已公开。
Claims (23)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2018102595452 | 2018-03-27 | ||
CN201810259545.2A CN110305212A (zh) | 2018-03-27 | 2018-03-27 | 抗cd47抗体及其用途 |
PCT/CN2019/079687 WO2019184912A1 (zh) | 2018-03-27 | 2019-03-26 | 抗cd47抗体及其用途 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN111630068A true CN111630068A (zh) | 2020-09-04 |
CN111630068B CN111630068B (zh) | 2022-08-19 |
Family
ID=68059477
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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CN201810259545.2A Pending CN110305212A (zh) | 2018-03-27 | 2018-03-27 | 抗cd47抗体及其用途 |
CN201980009230.5A Active CN111630068B (zh) | 2018-03-27 | 2019-03-26 | 抗cd47抗体及其用途 |
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Application Number | Title | Priority Date | Filing Date |
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CN201810259545.2A Pending CN110305212A (zh) | 2018-03-27 | 2018-03-27 | 抗cd47抗体及其用途 |
Country Status (3)
Country | Link |
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US (1) | US11655296B2 (zh) |
CN (2) | CN110305212A (zh) |
WO (1) | WO2019184912A1 (zh) |
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CN109422811A (zh) * | 2017-08-29 | 2019-03-05 | 信达生物制药(苏州)有限公司 | 抗cd47抗体及其用途 |
CN114761041A (zh) | 2019-07-16 | 2022-07-15 | 吉利德科学公司 | Hiv疫苗及其制备和使用方法 |
CN112969715B (zh) * | 2019-08-21 | 2022-03-18 | 和铂医药(上海)有限责任公司 | 一种抗cd47抗原结合蛋白及其应用 |
TW202124450A (zh) | 2019-10-18 | 2021-07-01 | 美商四十七股份有限公司 | 用於治療骨髓發育不良症候群及急性骨髓白血病之組合療法 |
US20220403023A1 (en) * | 2019-10-25 | 2022-12-22 | WuXi Biologics Ireland Limited | Novel anti-cd47 antibodies and uses thereof |
JP2022552748A (ja) | 2019-10-31 | 2022-12-19 | フォーティ セブン, インコーポレイテッド | 抗cd47及び抗cd20による血液癌の治療 |
WO2021130638A1 (en) | 2019-12-24 | 2021-07-01 | Carna Biosciences, Inc. | Diacylglycerol kinase modulating compounds |
WO2021163064A2 (en) | 2020-02-14 | 2021-08-19 | Jounce Therapeutics, Inc. | Antibodies and fusion proteins that bind to ccr8 and uses thereof |
WO2021170077A1 (zh) * | 2020-02-27 | 2021-09-02 | 信达生物制药(苏州)有限公司 | 抗cd47抗体和抗vegf抗体的组合及其用途 |
CN111454359B (zh) * | 2020-03-23 | 2021-06-29 | 倍而达药业(苏州)有限公司 | Cd47抗体或其免疫活性片段及应用 |
WO2022007947A1 (zh) * | 2020-07-10 | 2022-01-13 | 信达生物制药(苏州)有限公司 | 抗cd47抗体或其抗原结合片段和dna甲基化转移酶抑制剂的组合及其用途 |
US20230406921A1 (en) * | 2020-11-12 | 2023-12-21 | Mabwell (shanghai) Bioscience Co., Ltd. | Antibody and preparation method therefor |
CN112574310B (zh) * | 2020-12-11 | 2023-05-05 | 浙江博锐生物制药有限公司 | 抗SIRPα抗体及其用途 |
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CA3222439A1 (en) | 2021-06-23 | 2022-12-29 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
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KR20240005901A (ko) | 2021-06-23 | 2024-01-12 | 길리애드 사이언시즈, 인코포레이티드 | 디아실글리세롤 키나제 조절 화합물 |
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WO2023077030A1 (en) | 2021-10-29 | 2023-05-04 | Gilead Sciences, Inc. | Cd73 compounds |
US20240124412A1 (en) | 2021-12-22 | 2024-04-18 | Gilead Sciences, Inc. | Ikaros zinc finger family degraders and uses thereof |
US20230242508A1 (en) | 2021-12-22 | 2023-08-03 | Gilead Sciences, Inc. | Ikaros zinc finger family degraders and uses thereof |
TW202340168A (zh) | 2022-01-28 | 2023-10-16 | 美商基利科學股份有限公司 | Parp7抑制劑 |
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TW202345901A (zh) | 2022-04-05 | 2023-12-01 | 美商基利科學股份有限公司 | 用於治療結腸直腸癌之組合療法 |
US20230374036A1 (en) | 2022-04-21 | 2023-11-23 | Gilead Sciences, Inc. | Kras g12d modulating compounds |
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2018
- 2018-03-27 CN CN201810259545.2A patent/CN110305212A/zh active Pending
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2019
- 2019-03-26 US US16/966,081 patent/US11655296B2/en active Active
- 2019-03-26 WO PCT/CN2019/079687 patent/WO2019184912A1/zh active Application Filing
- 2019-03-26 CN CN201980009230.5A patent/CN111630068B/zh active Active
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Title |
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Also Published As
Publication number | Publication date |
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US11655296B2 (en) | 2023-05-23 |
US20200377593A1 (en) | 2020-12-03 |
CN111630068B (zh) | 2022-08-19 |
CN110305212A (zh) | 2019-10-08 |
WO2019184912A1 (zh) | 2019-10-03 |
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