CN111587114A - 用于调节人免疫应答的咪唑并嘧啶的用途 - Google Patents
用于调节人免疫应答的咪唑并嘧啶的用途 Download PDFInfo
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- CN111587114A CN111587114A CN201880086316.3A CN201880086316A CN111587114A CN 111587114 A CN111587114 A CN 111587114A CN 201880086316 A CN201880086316 A CN 201880086316A CN 111587114 A CN111587114 A CN 111587114A
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- Veterinary Medicine (AREA)
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- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
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- Engineering & Computer Science (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762586137P | 2017-11-14 | 2017-11-14 | |
| US62/586,137 | 2017-11-14 | ||
| PCT/US2018/061135 WO2019099578A1 (en) | 2017-11-14 | 2018-11-14 | Use of imidazopyrimidine for modulating human immune response |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111587114A true CN111587114A (zh) | 2020-08-25 |
Family
ID=66539100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880086316.3A Pending CN111587114A (zh) | 2017-11-14 | 2018-11-14 | 用于调节人免疫应答的咪唑并嘧啶的用途 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11730810B2 (https=) |
| EP (1) | EP3710007A4 (https=) |
| JP (2) | JP7382316B2 (https=) |
| KR (2) | KR102775718B1 (https=) |
| CN (1) | CN111587114A (https=) |
| WO (1) | WO2019099578A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7304855B2 (ja) | 2017-11-14 | 2023-07-07 | ザ チルドレンズ メディカル センター コーポレーション | 新規イミダゾピリミジン化合物およびそれらの使用 |
| CN111587114A (zh) * | 2017-11-14 | 2020-08-25 | 儿童医学中心公司 | 用于调节人免疫应答的咪唑并嘧啶的用途 |
| EP4277650A4 (en) * | 2021-01-15 | 2025-05-14 | The Board of Trustees of the Leland Stanford Junior University | Adjuvants to stimulate broad and persistent innate immunity against various antigens |
| WO2024151501A1 (en) * | 2023-01-09 | 2024-07-18 | The Children's Medical Center Corporation | Novel imidazopyrimidine compound and uses thereof |
Citations (7)
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|---|---|---|---|---|
| US20080058350A1 (en) * | 2006-08-28 | 2008-03-06 | Forest Laboratories Holdings Limited | Imidazopyridine and imidazopyrimidine derivatives |
| US20110053915A1 (en) * | 2007-12-14 | 2011-03-03 | Alla Chem, Llc | HETEROCYCLIC INHIBITORS OF AN Hh-SIGNAL CASCADE, MEDICINAL COMPOSITIONS BASED THEREON AND METHODS FOR TREATING DISEASES CAUSED BY THE ABERRANT ACTIVITY OF AN Hh-SIGNAL SYSTEM |
| CN102666541A (zh) * | 2009-10-22 | 2012-09-12 | 吉里德科学公司 | 用于治疗特别是病毒感染的嘌呤或脱氮嘌呤的衍生物 |
| CN103467590A (zh) * | 2013-09-02 | 2013-12-25 | 深圳大学 | 生物偶联体、制备其的嘌呤类化合物、合成方法、药用制剂以及其在免疫调节中的应用 |
| WO2014151784A1 (en) * | 2013-03-15 | 2014-09-25 | Irm Llc | Compounds and compositions for the treatment of parasitic diseases |
| CN105026397A (zh) * | 2013-03-05 | 2015-11-04 | 默克专利股份公司 | 作为抗癌剂的9-(芳基或杂芳基)-2-(吡唑基、吡咯烷基或环戊基)氨基嘌呤衍生物 |
| US9718848B2 (en) * | 2015-12-03 | 2017-08-01 | Glaxosmithkline Intellectual Property Development Limited | Compounds |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| DE69524598T2 (de) | 1994-06-20 | 2002-07-11 | Takeda Chemical Industries, Ltd. | Kondensierte imidazolderivate, ihre herstellung und verwendung |
| DE60018037T2 (de) | 1999-11-10 | 2006-01-12 | Ortho-Mcneil Pharmaceutical, Inc. | Substituierte 2-aryl-3-(heteroaryl)-imidazo[1,2-alpha]pyrimidine und ihren verwandten arzneimittel und verfahren |
| JP2001302667A (ja) | 2000-04-28 | 2001-10-31 | Bayer Ag | イミダゾピリミジン誘導体およびトリアゾロピリミジン誘導体 |
| EP1294723A1 (en) | 2000-05-24 | 2003-03-26 | MERCK SHARP & DOHME LTD. | 3-phenyl-imidazo-pyrimidine derivatives as ligands for gaba receptors |
| GB0128499D0 (en) * | 2001-11-28 | 2002-01-23 | Merck Sharp & Dohme | Therapeutic agents |
| EP1737459B1 (en) | 2004-03-19 | 2009-08-05 | Warner-Lambert Company LLC | Imidazopyridine and imidazopyrimidine derivatives as antibacterial agents |
| BRPI0513811A (pt) | 2004-07-27 | 2008-07-15 | Gilead Sciences Inc | imidazo [4,5-d] pirimidinas, seus usos e processos de preparação |
| WO2006029223A2 (en) * | 2004-09-08 | 2006-03-16 | Children's Medical Center Corporation | Method for stimulating the immune response of newborns |
| EP1910385B1 (en) | 2005-08-04 | 2013-07-24 | Sirtris Pharmaceuticals, Inc. | Benzothiazoles and thiazolopyridines as sirtuin modulators |
| US8093401B2 (en) | 2005-08-04 | 2012-01-10 | Sirtris Pharmaceuticals, Inc. | Sirtuin modulating compounds |
| EP1955077B1 (en) * | 2005-12-02 | 2012-06-13 | Sirtris Pharmaceuticals, Inc. | Mass spectrometry assays for acetyltransferase/deacetylase activity |
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| EP2103614A1 (en) | 2008-03-18 | 2009-09-23 | Santhera Pharmaceuticals (Schweiz) AG | Substituted imidazopyrimidine, imidazopyrazine and imidazopyridazine derivatives as melanocortin-4 receptor modulators |
| US20100168084A1 (en) | 2008-05-08 | 2010-07-01 | Huber L Julie | Therapeutic compounds and related methods of use |
| FR2933982A1 (fr) | 2008-07-18 | 2010-01-22 | Sanofi Aventis | Nouveaux derives imidazo°1,2-a!pyrimidine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation notamment comme inhibiteurs de met |
| UA103195C2 (uk) | 2008-08-11 | 2013-09-25 | Глаксосмитклайн Ллк | Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань |
| TWI617559B (zh) | 2010-12-22 | 2018-03-11 | 江蘇恆瑞醫藥股份有限公司 | 2-芳基咪唑并[1,2-b]嗒.2-苯基咪唑并[1,2-a]吡啶,和2-苯基咪唑并[1,2-a]吡衍生物 |
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- 2018-11-14 EP EP18878690.9A patent/EP3710007A4/en active Pending
- 2018-11-14 KR KR1020207016958A patent/KR102775718B1/ko active Active
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| US11730810B2 (en) | 2023-08-22 |
| EP3710007A1 (en) | 2020-09-23 |
| JP2023175686A (ja) | 2023-12-12 |
| JP7382316B2 (ja) | 2023-11-16 |
| WO2019099578A8 (en) | 2019-06-20 |
| WO2019099578A1 (en) | 2019-05-23 |
| JP2021502988A (ja) | 2021-02-04 |
| KR102775718B1 (ko) | 2025-03-06 |
| KR20200088398A (ko) | 2020-07-22 |
| KR20250030535A (ko) | 2025-03-05 |
| US20200282048A1 (en) | 2020-09-10 |
| EP3710007A4 (en) | 2021-12-15 |
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