CN111544504A - Paste for removing necrotic tissue and promoting tissue regeneration and preparation method thereof - Google Patents

Paste for removing necrotic tissue and promoting tissue regeneration and preparation method thereof Download PDF

Info

Publication number
CN111544504A
CN111544504A CN202010266750.9A CN202010266750A CN111544504A CN 111544504 A CN111544504 A CN 111544504A CN 202010266750 A CN202010266750 A CN 202010266750A CN 111544504 A CN111544504 A CN 111544504A
Authority
CN
China
Prior art keywords
layer
solution
paste
coating layer
freezing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202010266750.9A
Other languages
Chinese (zh)
Inventor
易军
王万春
严张仁
张乃忻
刘玥惠
李燕芳
毛文丽
王建刚
江鑫
陈思婷
黄子艳
张思娜
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangxi University of Traditional Chinese Medicine
Original Assignee
Jiangxi University of Traditional Chinese Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangxi University of Traditional Chinese Medicine filed Critical Jiangxi University of Traditional Chinese Medicine
Priority to CN202010266750.9A priority Critical patent/CN111544504A/en
Publication of CN111544504A publication Critical patent/CN111544504A/en
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/28Mercury; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • A61F2007/0203Cataplasms, poultices or compresses, characterised by their contents; Bags therefor
    • A61F2007/0206Cataplasms, poultices or compresses, characterised by their contents; Bags therefor containing organic solids or fibres
    • A61F2007/0207Plants, dried plants, seeds or fruits
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/35Extraction with lipophilic solvents, e.g. Hexane or petrol ether

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention discloses a paste for removing necrotic tissue and promoting tissue regeneration and a preparation method thereof. The invention has the following beneficial effects: the components which cannot be crushed are frozen and crushed, and the internal heat is removed after the ointment is prepared, so that the curative effect is good; the finished product is in a paste type, is convenient to store, is not easy to deteriorate and is convenient to use; the cold coating layer is arranged, and the cold coating layer is combined in a cold coating mode in the using process, so that the curative effect is enhanced; when the frozen frankincense myrrh and the like are resin medicinal materials, the resin medicinal materials are stored through a freezing box unit, and the freezing box unit can be stacked and is convenient to take and use.

Description

Paste for removing necrotic tissue and promoting tissue regeneration and preparation method thereof
Technical Field
The invention relates to a paste for removing necrotic tissue and promoting tissue regeneration and a preparation method thereof, belonging to the technical field of tissue regeneration paste.
Background
Sores and ulcers refer to the general term for all superficial suppuration and infectious diseases caused by various pathogenic factors attacking the human body, including acute and chronic diseases. Ancient China generally refers to a variety of surgical diseases, and the latter time divides surgery into sores and ulcers and miscellaneous syndromes. Sores and ulcers are usually caused by the stagnation of qi and blood due to the invasion of toxic pathogen and heat burning blood. The external medicine comprises the contents of pyogenic infection, ulcer, carbuncle, gangrene, furuncle, multiple abscess, sputum, scrofula and related skin diseases on the body surface, is the most common diseases in surgical diseases of traditional Chinese medicine, has the characteristics of rapid onset of disease, serious disease conditions and the like, can cause the furuncle to become yellow on the face (septicemia or septicopyemia in western medicine), and can easily cause serious consequences of injuring tendons and bones on hands and feet. After infection of the wound, a sore is formed. At present, a plurality of traditional Chinese medicine formulas have certain curative effects on sores and ulcers, but the preparation process is not standard enough, and finished products are not easy to store.
Disclosure of Invention
The technical problem to be solved by the invention is to provide the paste for removing the necrotic tissue and promoting tissue regeneration and the preparation method thereof.
The invention is realized by the following scheme: the paste comprises a putrefaction-removing and granulation-promoting layer, wherein a cold coating layer is arranged at the upper end of the putrefaction-removing and granulation-promoting layer, a back lining layer is arranged at the upper end of the cold coating layer, and a tearable coating layer is arranged at the lower end of the putrefaction-removing and granulation-promoting layer.
The cold coating layer is made of polymer gel, and the backing layer is made of non-woven fabric.
The slough-removing and muscle-growing layer is prepared from angelica sinensis, radix angelicae, liquorice, lithospermum, frankincense, myrrh, earthworm, pearl powder, dragon's blood, white wax, calomel and sesame oil.
A preparation method of a paste for removing necrotic tissue and promoting tissue regeneration comprises the following components by weight: 30-50g of angelica, 5-15g of angelica dahurica, 26-30g of liquorice, 2-4g of lithospermum, 10-20g of frankincense, 10-14g of myrrh, 15-25g of earthworm, 6-10g of pearl powder, 8-12g of dragon's blood, 30-40g of white wax, 6-10g of calomel and 500g of sesame oil.
A preparation method of the paste for removing the necrotic tissue and promoting tissue regeneration comprises the following steps:
soaking angelica, angelica dahurica, liquorice and lithospermum in sesame oil to obtain a solution A;
step two, freezing frankincense, myrrh and earthworm, and then powdering by hands;
step three, manually powdering the dragon's blood;
step four, heating the solution A with big fire, stirring until water drops form beads, and filtering out dregs of a decoction to obtain a solution B;
step five, heating the solution B with soft fire, stirring, sequentially adding the treated frankincense, myrrh, earthworm, dragon's blood and pearl powder, and uniformly mixing to obtain a solution C;
sixthly, adding white wax into the solution C, melting the white wax by mild fire, adding calomel, and uniformly mixing to obtain a solution D;
seventhly, putting the solution D into a refrigerator for refrigeration, and taking out after 3D to form a putrefaction-free myogenic layer;
and step eight, arranging a cold coating layer on the putrefaction-removing myogenic layer, arranging a back lining layer on the cold coating layer, and arranging a coating layer at the lower end of the putrefaction-removing myogenic layer.
A preparation method of the paste for removing the necrotic tissue and promoting tissue regeneration comprises the following steps:
soaking angelica, angelica dahurica, liquorice and lithospermum in sesame oil for 3-5 days to obtain a solution A;
step two, freezing frankincense, myrrh and earthworm, and then powdering by hands;
step three, manually powdering the dragon's blood;
step four, heating the solution A at the temperature of 150 ℃, stirring at the stirring speed of 90r/min until water drops form beads, and filtering out dregs to obtain a solution B;
step five, heating the solution B at the temperature of 60 ℃, stirring at the stirring speed of 45r/min, sequentially adding the treated frankincense, the treated myrrh, the treated earthworm, the treated dragon's blood and the treated pearl powder, and uniformly mixing to obtain a solution C;
sixthly, adding white wax into the solution C, melting the white wax by mild fire, adding calomel, and uniformly mixing to obtain a solution D;
and seventhly, putting the solution D into a refrigerator for cold storage at 6 ℃ and taking out after 3D.
And step eight, arranging a cold coating layer on the putrefaction-removing myogenic layer, arranging a back lining layer on the cold coating layer, and arranging a coating layer at the lower end of the putrefaction-removing myogenic layer.
And putting the frankincense, the myrrh and the earthworm in the step two into a freezing box, and then putting the box into a refrigerator for freezing treatment.
The freezing box is composed of a plurality of freezing box units and a cover plate, each freezing box unit is provided with a clamping ring, the freezing box units and the clamping rings are circular, and the diameter of each clamping ring is larger than that of each freezing box unit.
The box unit card that freezes that is located the top is gone into and is located the below the snap ring of freezing the box unit, it is a plurality of freeze the box unit and stack together layer upon layer, the apron lid is at the top in the snap ring of freezing the box unit, the upper end of apron is equipped with carries the piece.
And a rubber layer is arranged on the inner wall of the clamping ring.
The invention has the beneficial effects that:
1. the paste for removing the necrotic tissue and promoting tissue regeneration provided by the invention is prepared by freezing the components which cannot be crushed and then crushing the components, and simultaneously, the paste is subjected to fire-removing treatment after the preparation is finished, so that the curative effect is good;
2. the final finished product of the paste for removing the necrotic tissue and promoting tissue regeneration is paste-type, is convenient to store, is not easy to deteriorate, and is convenient and fast to use;
3. the finished product of the paste for removing the necrotic tissue and promoting tissue regeneration is provided with the cold coating layer, and the cold coating layer is combined with the cold coating layer in the using process to enhance the curative effect;
4. the paste for removing the necrotic tissue and promoting tissue regeneration is stored by the freezing box units when the frozen frankincense, myrrh and the like are resin medicinal materials, and the freezing box units can be stacked and are convenient to take and use.
Drawings
Fig. 1 is a schematic front view of a section structure of a paste for removing necrotic tissue and promoting tissue regeneration of the present invention.
FIG. 2 is a schematic diagram of the front cross-sectional structure of a freezing box used in the preparation method of the paste for removing necrotic tissue and promoting tissue regeneration of the present invention.
In the figure: 1 is a slough-removing and granulation-promoting layer, 2 is a cold coating layer, 3 is a back lining layer, 4 is a coating layer, 5 is a freezing box unit, 6 is a cover plate, 7 is a snap ring, 8 is a lifting block, and 9 is a rubber layer.
Detailed Description
The invention is further described below with reference to fig. 1-2, without limiting the scope of the invention.
In which like parts are designated by like reference numerals. It is noted that the terms "front", "back", "left", "right", "upper" and "lower" used in the following description refer to directions in the drawings, the terms "inner" and "outer" refer to directions toward and away from, respectively, the geometric center of a particular component, and the drawings are in greatly simplified form and employ non-precise ratios, merely for the purpose of facilitating and distinctly aiding in the description of the embodiments of the present invention.
In the following description, for purposes of clarity, not all features of an actual implementation are described, well-known functions or constructions are not described in detail since they would obscure the invention with unnecessary detail, it being understood that in the development of any actual embodiment, numerous implementation details must be set forth in order to achieve the developer's specific goals, such as compliance with system-related and business-related constraints, changing from one implementation to another, and it being recognized that such development effort might be complex and time consuming, but would nevertheless be a routine undertaking for those of ordinary skill in the art.
Example 1: a paste for removing necrotic tissue and promoting granulation and its preparation method, it includes removing the rotten flesh layer 1, the upper end of removing the rotten flesh layer 1 has a layer of cold coating 2, the upper end of the cold compress layer 2 has a layer of back lining 3, the lower end of removing the rotten flesh layer 1 has a layer of coating 4 that can be torn, the cold compress layer 2 is made of macromolecule gel, the back lining 3 is made of non-woven fabrics.
A preparation method of a paste for removing necrotic tissue and promoting granulation, wherein a slough-removing and granulation-promoting layer 1 is prepared from Chinese angelica, angelica dahurica, liquorice, lithospermum, frankincense, myrrh, earthworm, pearl powder, dragon's blood, white wax, calomel and sesame oil, and the weight contents of the components are as follows: 30g of angelica, 5g of angelica dahurica, 26g of liquorice, 2g of lithospermum, 10g of frankincense, 10g of myrrh, 15g of earthworm, 6g of pearl powder, 8g of dragon's blood, 30g of white wax, 6g of calomel and 500g of sesame oil.
A preparation method of the paste for removing the necrotic tissue and promoting tissue regeneration comprises the following steps:
soaking Chinese angelica, angelica dahurica, liquorice and lithospermum in sesame oil for 3 days to obtain a solution A;
step two, freezing frankincense, myrrh and earthworm, and then powdering by hands;
step three, manually powdering the dragon's blood;
step four, heating the solution A at the temperature of 150 ℃, stirring at the stirring speed of 90r/min until water drops form beads, and filtering out dregs to obtain a solution B;
step five, heating the solution B at the temperature of 60 ℃, stirring at the stirring speed of 45r/min, sequentially adding the treated frankincense, the treated myrrh, the treated earthworm, the treated dragon's blood and the treated pearl powder, and uniformly mixing to obtain a solution C;
sixthly, adding white wax into the solution C, melting the white wax by mild fire, adding calomel, and uniformly mixing to obtain a solution D;
and seventhly, putting the solution D into a refrigerator for cold storage at 6 ℃ and taking out after 3D.
And step eight, arranging a cold coating layer 2 on the necrosis-removing and granulation-promoting layer 1, arranging a back lining layer 3 on the cold coating layer 2, and arranging an envelope layer 4 at the lower end of the necrosis-removing and granulation-promoting layer 1.
And putting the frankincense, the myrrh and the earthworm in the step two into a freezing box, and then putting the box into a refrigerator for freezing treatment.
The freezing box is composed of a plurality of freezing box units 5 and a cover plate 6, each freezing box unit 5 is provided with a clamping ring 7, the freezing box units 5 and the clamping rings 7 are both circular, and the diameter of each clamping ring 7 is larger than that of each freezing box unit 5.
The freezing box unit 5 positioned above is clamped into the clamping ring 7 of the freezing box unit 5 positioned below, the freezing box units 5 are overlapped layer by layer, the cover plate 6 is covered in the clamping ring 7 of the uppermost freezing box unit 5, and the upper end of the cover plate 6 is provided with the lifting block 8.
The inner wall of the snap ring 7 is provided with a rubber layer 9.
Example 2: a paste for removing necrotic tissue and promoting granulation and its preparation method, it includes removing the rotten flesh layer 1, the upper end of removing the rotten flesh layer 1 has a layer of cold coating 2, the upper end of the cold compress layer 2 has a layer of back lining 3, the lower end of removing the rotten flesh layer 1 has a layer of coating 4 that can be torn, the cold compress layer 2 is made of macromolecule gel, the back lining 3 is made of non-woven fabrics.
A preparation method of a paste for removing necrotic tissue and promoting granulation, wherein a slough-removing and granulation-promoting layer 1 is prepared from Chinese angelica, angelica dahurica, liquorice, lithospermum, frankincense, myrrh, earthworm, pearl powder, dragon's blood, white wax, calomel and sesame oil, and the weight contents of the components are as follows: 50g of angelica, 15g of angelica dahurica, 30g of liquorice, 4g of lithospermum, 20g of frankincense, 14g of myrrh, 25g of earthworm, 10g of pearl powder, 12g of dragon's blood, 40g of white wax, 10g of calomel and 500g of sesame oil.
A preparation method of the paste for removing the necrotic tissue and promoting tissue regeneration comprises the following steps:
soaking Chinese angelica, angelica dahurica, liquorice and lithospermum in sesame oil for 5 days to obtain a solution A;
step two, freezing frankincense, myrrh and earthworm, and then powdering by hands;
step three, manually powdering the dragon's blood;
step four, heating the solution A at the temperature of 150 ℃, stirring at the stirring speed of 90r/min until water drops form beads, and filtering out dregs to obtain a solution B;
step five, heating the solution B at the temperature of 60 ℃, stirring at the stirring speed of 45r/min, sequentially adding the treated frankincense, the treated myrrh, the treated earthworm, the treated dragon's blood and the treated pearl powder, and uniformly mixing to obtain a solution C;
sixthly, adding white wax into the solution C, melting the white wax by mild fire, adding calomel, and uniformly mixing to obtain a solution D;
and seventhly, putting the solution D into a refrigerator for cold storage at 6 ℃ and taking out after 3D.
And step eight, arranging a cold coating layer 2 on the necrosis-removing and granulation-promoting layer 1, arranging a back lining layer 3 on the cold coating layer 2, and arranging an envelope layer 4 at the lower end of the necrosis-removing and granulation-promoting layer 1.
And putting the frankincense, the myrrh and the earthworm in the step two into a freezing box, and then putting the box into a refrigerator for freezing treatment.
The freezing box is composed of a plurality of freezing box units 5 and a cover plate 6, each freezing box unit 5 is provided with a clamping ring 7, the freezing box units 5 and the clamping rings 7 are both circular, and the diameter of each clamping ring 7 is larger than that of each freezing box unit 5.
The freezing box unit 5 positioned above is clamped into the clamping ring 7 of the freezing box unit 5 positioned below, the freezing box units 5 are overlapped layer by layer, the cover plate 6 is covered in the clamping ring 7 of the uppermost freezing box unit 5, and the upper end of the cover plate 6 is provided with the lifting block 8.
The inner wall of the snap ring 7 is provided with a rubber layer 9.
Example 3: a paste for removing necrotic tissue and promoting granulation and its preparation method, it includes removing the rotten flesh layer 1, the upper end of removing the rotten flesh layer 1 has a layer of cold coating 2, the upper end of the cold compress layer 2 has a layer of back lining 3, the lower end of removing the rotten flesh layer 1 has a layer of coating 4 that can be torn, the cold compress layer 2 is made of macromolecule gel, the back lining 3 is made of non-woven fabrics.
A preparation method of a paste for removing necrotic tissue and promoting granulation, wherein a slough-removing and granulation-promoting layer 1 is prepared from Chinese angelica, angelica dahurica, liquorice, lithospermum, frankincense, myrrh, earthworm, pearl powder, dragon's blood, white wax, calomel and sesame oil, and the weight contents of the components are as follows: 40g of angelica, 10g of angelica dahurica, 280g of liquorice, 3g of lithospermum, 15g of frankincense, 12g of myrrh, 20g of earthworm, 8g of pearl powder, 10g of dragon's blood, 35g of white wax, 8g of calomel and 500g of sesame oil.
A preparation method of the paste for removing the necrotic tissue and promoting tissue regeneration comprises the following steps:
soaking Chinese angelica, angelica dahurica, liquorice and lithospermum in sesame oil for 4 days to obtain a solution A;
step two, freezing frankincense, myrrh and earthworm, and then powdering by hands;
step three, manually powdering the dragon's blood;
step four, heating the solution A at the temperature of 150 ℃, stirring at the stirring speed of 90r/min until water drops form beads, and filtering out dregs to obtain a solution B;
step five, heating the solution B at the temperature of 60 ℃, stirring at the stirring speed of 45r/min, sequentially adding the treated frankincense, the treated myrrh, the treated earthworm, the treated dragon's blood and the treated pearl powder, and uniformly mixing to obtain a solution C;
sixthly, adding white wax into the solution C, melting the white wax by mild fire, adding calomel, and uniformly mixing to obtain a solution D;
and seventhly, putting the solution D into a refrigerator for cold storage at 6 ℃ and taking out after 3D.
And step eight, arranging a cold coating layer 2 on the necrosis-removing and granulation-promoting layer 1, arranging a back lining layer 3 on the cold coating layer 2, and arranging an envelope layer 4 at the lower end of the necrosis-removing and granulation-promoting layer 1.
And putting the frankincense, the myrrh and the earthworm in the step two into a freezing box, and then putting the box into a refrigerator for freezing treatment.
The freezing box is composed of a plurality of freezing box units 5 and a cover plate 6, each freezing box unit 5 is provided with a clamping ring 7, the freezing box units 5 and the clamping rings 7 are both circular, and the diameter of each clamping ring 7 is larger than that of each freezing box unit 5.
The freezing box unit 5 positioned above is clamped into the clamping ring 7 of the freezing box unit 5 positioned below, the freezing box units 5 are overlapped layer by layer, the cover plate 6 is covered in the clamping ring 7 of the uppermost freezing box unit 5, and the upper end of the cover plate 6 is provided with the lifting block 8.
The inner wall of the snap ring 7 is provided with a rubber layer 9.
Although the invention has been described and illustrated in some detail, it should be understood that various modifications may be made to the described embodiments or equivalents may be substituted, as will be apparent to those skilled in the art, without departing from the spirit of the invention.

Claims (10)

1. The paste for removing the necrotic tissue and promoting tissue regeneration is characterized in that: the anti-corrosion and anti-corrosion fabric comprises a corrosion-removing and anti-corrosion muscle layer (1), wherein a cold coating layer (2) is arranged at the upper end of the corrosion-removing and anti-corrosion muscle layer (1), a back lining layer (3) is arranged at the upper end of the cold coating layer (2), and a tearable coating layer (4) is arranged at the lower end of the corrosion-removing and anti-corrosion muscle layer (1).
2. The paste of claim 1, which is characterized by: the cold coating layer (2) is made of polymer gel, and the backing layer (3) is made of non-woven fabric.
3. The paste of claim 1, which is characterized by: the slough-removing and muscle-growing layer (1) is prepared from angelica sinensis, radix angelicae, liquorice, lithospermum, frankincense, myrrh, lumbricus, pearl powder, dragon's blood, white wax, calomel and sesame oil.
4. The paste of claim 3, which is characterized by: the weight contents of the components are as follows: 30-50g of angelica, 5-15g of angelica dahurica, 26-30g of liquorice, 2-4g of lithospermum, 10-20g of frankincense, 10-14g of myrrh, 15-25g of earthworm, 6-10g of pearl powder, 8-12g of dragon's blood, 30-40g of white wax, 6-10g of calomel and 500g of sesame oil.
5. A preparation method of the paste for removing the necrotic tissue and promoting tissue regeneration is characterized in that: the method comprises the following steps:
soaking angelica, angelica dahurica, liquorice and lithospermum in sesame oil to obtain a solution A;
step two, freezing frankincense, myrrh and earthworm, and then powdering by hands;
step three, manually powdering the dragon's blood;
step four, heating the solution A with big fire, stirring until water drops form beads, and filtering out dregs of a decoction to obtain a solution B;
step five, heating the solution B with soft fire, stirring, sequentially adding the treated frankincense, myrrh, earthworm, dragon's blood and pearl powder, and uniformly mixing to obtain a solution C;
sixthly, adding white wax into the solution C, melting the white wax by mild fire, adding calomel, and uniformly mixing to obtain a solution D;
seventhly, putting the solution D into a refrigerator for refrigeration, and taking out after 3D to form a putrefaction-free myogenic layer (1);
step eight, arranging a cold coating layer (2) on the putrefaction-removing myogenic layer (1), arranging a back lining layer (3) on the cold coating layer (2), and arranging a coating layer (4) at the lower end of the putrefaction-removing myogenic layer (1).
6. The method for preparing paste for removing necrotic tissue and promoting tissue regeneration as claimed in claim 5, wherein: the method comprises the following steps:
soaking angelica, angelica dahurica, liquorice and lithospermum in sesame oil for 3-5 days to obtain a solution A;
step two, freezing frankincense, myrrh and earthworm, and then powdering by hands;
step three, manually powdering the dragon's blood;
step four, heating the solution A at the temperature of 150 ℃, stirring at the stirring speed of 90r/min until water drops form beads, and filtering out dregs to obtain a solution B;
step five, heating the solution B at the temperature of 60 ℃, stirring at the stirring speed of 45r/min, sequentially adding the treated frankincense, the treated myrrh, the treated earthworm, the treated dragon's blood and the treated pearl powder, and uniformly mixing to obtain a solution C;
sixthly, adding white wax into the solution C, melting the white wax by mild fire, adding calomel, and uniformly mixing to obtain a solution D;
and seventhly, putting the solution D into a refrigerator for cold storage at 6 ℃ and taking out after 3D.
Step eight, arranging a cold coating layer (2) on the putrefaction-removing myogenic layer (1), arranging a back lining layer (3) on the cold coating layer (2), and arranging a coating layer (4) at the lower end of the putrefaction-removing myogenic layer (1).
7. The method for preparing paste for removing necrotic tissue and promoting tissue regeneration as claimed in claim 6, wherein: and putting the frankincense, the myrrh and the earthworm in the step two into a freezing box, and then putting the box into a refrigerator for freezing treatment.
8. The method for preparing paste for removing necrotic tissue and promoting tissue regeneration as claimed in claim 7, wherein: the freezing box is composed of a plurality of freezing box units (5) and a cover plate (6), each freezing box unit (5) is provided with a clamping ring (7), the freezing box units (5) and the clamping rings (7) are all circular, and the diameter of the clamping rings (7) is larger than that of the freezing box units (5).
9. The method for preparing paste for removing necrotic tissue and promoting tissue regeneration as claimed in claim 8, wherein: the box unit (5) card that freezes that is located the top is gone into and is located the below in snap ring (7) of freezing box unit (5), it is a plurality of freeze box unit (5) stack together layer upon layer, apron (6) lid is topmost freeze in snap ring (7) of box unit (5), the upper end of apron (6) is equipped with carries piece (8).
10. The method for preparing paste for removing necrotic tissue and promoting tissue regeneration as claimed in claim 9, wherein: the inner wall of the snap ring (7) is provided with a rubber layer (9).
CN202010266750.9A 2020-04-07 2020-04-07 Paste for removing necrotic tissue and promoting tissue regeneration and preparation method thereof Pending CN111544504A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010266750.9A CN111544504A (en) 2020-04-07 2020-04-07 Paste for removing necrotic tissue and promoting tissue regeneration and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010266750.9A CN111544504A (en) 2020-04-07 2020-04-07 Paste for removing necrotic tissue and promoting tissue regeneration and preparation method thereof

Publications (1)

Publication Number Publication Date
CN111544504A true CN111544504A (en) 2020-08-18

Family

ID=71998227

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010266750.9A Pending CN111544504A (en) 2020-04-07 2020-04-07 Paste for removing necrotic tissue and promoting tissue regeneration and preparation method thereof

Country Status (1)

Country Link
CN (1) CN111544504A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112545756A (en) * 2020-11-25 2021-03-26 周建大 Preparation method of medical ozone oil-silicone foam patch

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101791364A (en) * 2010-04-28 2010-08-04 董崇孝 Traditional Chinese medicine composition capable of promoting wound healing and preparation method thereof
CN107982398A (en) * 2017-11-24 2018-05-04 王志强 A kind of putrefaction-removing granulation-promoting paste and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101791364A (en) * 2010-04-28 2010-08-04 董崇孝 Traditional Chinese medicine composition capable of promoting wound healing and preparation method thereof
CN107982398A (en) * 2017-11-24 2018-05-04 王志强 A kind of putrefaction-removing granulation-promoting paste and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
梁勇才 等: "《中国外治妙方》", 31 January 2003, 科学技术文献出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112545756A (en) * 2020-11-25 2021-03-26 周建大 Preparation method of medical ozone oil-silicone foam patch

Similar Documents

Publication Publication Date Title
CN1481833A (en) Medication of external use for burn or scald
CN111544504A (en) Paste for removing necrotic tissue and promoting tissue regeneration and preparation method thereof
CN104225258A (en) Traditional Chinese medicine composition for promoting wound healing
CN1895485A (en) Medicine for treating burn and scald
CN113197844A (en) Scar-free tissue regeneration promoting paste
CN105125586A (en) Isinglass oral ulcer film as well as preparation method and application thereof
WO2017215681A1 (en) Formula for treating injuries from knocks and falls
CN104548008B (en) A kind of pharmaceutical composition prevented and/or treat allergic skin diseases and preparation method thereof
CN110200926A (en) Composite reactive freeze-dried powder and its preparation method and application
CN105168941A (en) Traditional Chinese medicine preparation for promoting cesarean wound healing and preparation method therefor
CN105435294A (en) Bandage for diminishing inflammation and stopping bleeding of injury and preparation method thereof
CN1245711A (en) Channel-freeing network-quickening strong bone-joining powder
CN107485675A (en) A kind of wound Regeneration and Repair removing necrosis, promoting granulation powder and preparation method and application method
CN105748619B (en) Medicine for treating plasma cell mastitis and preparation method thereof
CN1233333C (en) Process for preparing Tibetan medicines
CN1151805C (en) Medicinal liquid for curing scald and burn
CN107854597B (en) Combined application for acute mastitis and preparation method thereof
CN105687630A (en) Angelica sinensis-elephant skin hide sore and ulcer paste and preparation method thereof
CN106860767A (en) A kind of Chinese medicine preparation closed for promoting sore to recover from injury and preparation method thereof
CN1270748C (en) Chinese medicinal composition for treating sore and wound infection
CN105168258A (en) Anti-injury preparation with earthworm and method for preparing anti-injury preparation
CN115531601A (en) Hydrogel dressing for relieving skin photoelectric treatment postoperative inflammatory reaction and preparation method thereof
CN1190012A (en) Plaster for burn and scald and its preparation
CN106236900A (en) A kind of for compound medicine treating burn and preparation method thereof
CN106421926A (en) Pure natural traditional Chinese medicine and marine organism active immunization bone

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20200818