CN111480587A - Micro-control mouse cage for activity in microbiological medical test and activity measuring method - Google Patents
Micro-control mouse cage for activity in microbiological medical test and activity measuring method Download PDFInfo
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- CN111480587A CN111480587A CN202010367364.9A CN202010367364A CN111480587A CN 111480587 A CN111480587 A CN 111480587A CN 202010367364 A CN202010367364 A CN 202010367364A CN 111480587 A CN111480587 A CN 111480587A
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- 230000000694 effects Effects 0.000 title claims abstract description 46
- 238000000034 method Methods 0.000 title claims abstract description 22
- 238000010339 medical test Methods 0.000 title claims description 9
- 230000002906 microbiologic effect Effects 0.000 title claims description 9
- 241000555745 Sciuridae Species 0.000 claims abstract description 24
- 238000012360 testing method Methods 0.000 claims abstract description 13
- 241000699666 Mus <mouse, genus> Species 0.000 claims description 21
- 239000000463 material Substances 0.000 claims description 14
- 238000004140 cleaning Methods 0.000 claims description 13
- 241000699670 Mus sp. Species 0.000 claims description 9
- 238000010438 heat treatment Methods 0.000 claims description 7
- 238000004891 communication Methods 0.000 claims description 4
- 230000001276 controlling effect Effects 0.000 claims 1
- 238000011161 development Methods 0.000 description 11
- 230000008569 process Effects 0.000 description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 230000006872 improvement Effects 0.000 description 4
- 210000001503 joint Anatomy 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 210000003608 fece Anatomy 0.000 description 3
- 230000000384 rearing effect Effects 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 238000005192 partition Methods 0.000 description 2
- 238000010827 pathological analysis Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000002550 fecal effect Effects 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000003032 molecular docking Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
- A01K1/03—Housing for domestic or laboratory animals
- A01K1/031—Cages for laboratory animals; Cages for measuring metabolism of animals
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/0047—Air-conditioning, e.g. ventilation, of animal housings
- A01K1/0076—Arrangement of heaters or heat exchangers
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/01—Removal of dung or urine, e.g. from stables
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
- A01K1/035—Devices for use in keeping domestic animals, e.g. fittings in housings or dog beds
- A01K1/0356—Feeding or drinking devices associated with cages
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/1101—Detecting tremor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/40—Animals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/42—Evaluating a particular growth phase or type of persons or animals for laboratory research
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- Zoology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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Abstract
The invention relates to the field of biomedical tests, in particular to a method for measuring an activity micro-control squirrel cage and an activity in a biomedical test. The multifunctional excrement collecting device comprises a vertical stand pipe (8), more than one multipurpose guide pipe (4) is arranged on the vertical stand pipe (8), the multipurpose guide pipes (4) are annularly distributed on the vertical stand pipe (8) for one circle, the lower part of each multipurpose guide pipe (4) is closed, and an excrement pipe (2) extends out of the closed part; a circle of connecting transverse shafts (21) are arranged upwards on the multipurpose guide pipe (4), a circle of guide walls (5) are fixed on the connecting transverse shafts (21), and an opening below the guide walls (5) leads to an opening above the multipurpose guide pipe (4); a fixed plate is arranged on the vertical pipe (8), and a sensor is arranged on the fixed plate; the cage body is placed on the fixing plate and presses the sensor; the sensor is capable of measuring the frequency of activity of the organisms in the cage; both cages were placed on a level.
Description
Technical Field
The invention relates to the field of biomedical tests, in particular to a method for measuring an activity micro-control squirrel cage and an activity in a biomedical test.
Background
The existing mouse feeding process has the following problems:
1. the activity amount cannot be measured;
2. the feed cannot be uniformly fed;
3. the sanitation cleaning can not be uniformly carried out;
4. occupying space.
Disclosure of Invention
The purpose of the invention is as follows: in order to provide a more effective method for micro-control mouse cage of activity and determination of activity in biomedical tests, the specific purpose is to see a plurality of substantial technical effects of the concrete implementation part.
In order to achieve the purpose, the invention adopts the following technical scheme:
the first scheme is as follows:
the micro-control squirrel cage for the activity of the microbiological medical test is characterized in that the cleaning device comprises a base 1 or a bottom 16; the multifunctional excrement collecting device also comprises a vertical stand pipe 8, more than one multipurpose guide pipe 4 is arranged on the vertical stand pipe 8, the multipurpose guide pipes 4 are circularly distributed on the vertical stand pipe 8, the lower part of each multipurpose guide pipe 4 is closed, and the closed part extends out of the excrement pipe 2; a circle of connecting transverse shafts 21 are arranged on the multipurpose guide pipe 4 in an upward mode, a circle of guide walls 5 are fixed on the connecting transverse shafts 21, and openings below the guide walls 5 guide openings above the multipurpose guide pipe 4;
a fixed plate is arranged on the vertical pipe 8, and a sensor is arranged on the fixed plate;
the cage body is placed on the fixing plate and presses the sensor;
the sensor is capable of measuring the frequency of activity of the organisms in the cage;
both cages were placed on a level.
The invention has the further technical scheme that the sensor is a vibration sensor; the vibration sensor is connected with the central control system in a communication mode.
The invention has the further technical scheme that the position of the squirrel cage bottom corresponding to the sensor on the fixing plate comprises a groove matched with the sensor.
The invention has the further technical scheme that the bottom of the squirrel cage is provided with a grid; the rat excrement is guided to the multipurpose guide pipe 4 and then guided to the excrement pipe 2 to be collected.
The invention further adopts the technical scheme that the base 11 is of a flange structure, the flange comprises a circle of threads and a corresponding mounting plate, and the mounting plate comprises a plurality of threaded holes which are arranged in parallel.
The further technical scheme of the invention is that the cage comprises a rearing cage groove 24, the cage body comprises a fixed ingress pipe 12, the fixed ingress pipe 12 is guided into the rearing cage groove 24, the fixed ingress pipe 12 extends out to be an inclined pipeline, and the inclined pipeline can be butted against the fixed ingress pipe 12 in a butt joint port 26 on the vertical pipe 8; the fixed inlet pipe 12 is communicated with the feeding port 10 on the upper plate 9 above; each feeding port 10 is capable of holding material down and directing the material through a stationary intake tube 12 into a cage tub 24.
The further technical scheme of the invention is that the vibration sensor is connected with a signal wire 22 in a communication way, and the signal wire is connected with a central control part; the signal line 22 is located in the vertical riser 8; a fixed lead-in pipe 12 is also located in the vertical riser 8.
The invention further adopts the technical scheme that the base is square, and the moving wheels are arranged below the square base.
The further technical proposal of the invention is that the vertical riser 8 also comprises a heating wire 23; the heating wire 23 can be electrified to heat the mouse cage.
A method for measuring the activity of a mouse in a biomedical test is characterized in that the micro-control mouse cage is utilized;
a plurality of mice are experimental mice;
the more each mouse moves, the higher the micro-vibration times and frequency of the mouse cage detected by the vibration sensor;
counting the time and frequency of the triggering of the vibration sensor; the activity of the mouse can be evaluated in an index way.
Scheme II:
the method for automatically cleaning and accurately feeding the three-dimensional mouse in the medical laboratory is characterized in that the cleaning device comprises a base 1 or a bottom 16; the multifunctional excrement collecting device also comprises a vertical stand pipe 8, more than one multipurpose guide pipe 4 is arranged on the vertical stand pipe 8, the multipurpose guide pipes 4 are circularly distributed on the vertical stand pipe 8, the lower part of each multipurpose guide pipe 4 is closed, and the closed part extends out of the excrement pipe 2; a circle of connecting transverse shafts 21 are arranged on the multipurpose guide pipe 4 in an upward mode, a circle of guide walls 5 are fixed on the connecting transverse shafts 21, and openings below the guide walls 5 guide openings above the multipurpose guide pipe 4;
the cage comprises a cage trough 24, the cage body comprises a fixed ingress pipe 12, the fixed ingress pipe 12 is guided into the cage trough 24, the fixed ingress pipe 12 extends out to form an inclined pipeline, and the inclined pipeline can butt against the fixed ingress pipe 12 in a butt joint 26 on the vertical pipe 8; the fixed inlet pipe 12 is communicated with the feeding port 10 on the upper plate 9 above; each feeding port 10 can be used for placing materials downwards and guiding the materials into a feeding cage groove 24 through a fixed inlet pipe 12;
two cages are placed at one height; the cage body is placed on the fixing plate and presses the sensor;
the cage is semicircular overall, and an arc-shaped groove 13 in the middle of the semicircle is matched with the vertical pipe 8; the cage body comprises a hand-holding groove 15, the hand-holding groove 15 can be used for holding a bottle 18, and the mouth of the bottle 18 can correspond to a feeding cage groove 24;
each feeding port 10 can be used for placing materials downwards and guiding the materials into a feeding cage groove 24 through a fixed inlet pipe 12; therefore, different drugs or microbial agents can be fed to a plurality of squirrel cages in a differentiated mode for comparison; people do not need to look for numbers and feed one by one, and all accurate operations can be realized on one upper plate 9;
the bottom of the squirrel cage is provided with a grid; the white rat excrement is guided into the multipurpose guide pipe 4 and then guided into the excrement pipe 2 to be collected;
the space is saved in three-dimensional breed and experiment, can realize space make full use of in local space.
The invention further has the technical scheme that the two cages are placed at a same height and are arranged in parallel, the cages belong to a parallel test, and the white rat excrement led out by the multipurpose guide pipes 4 corresponding to the two cages can be guided into the multipurpose guide pipes 4 and then guided into the excrement pipe 2; for individual collection for pathological analysis of the feces.
The invention further adopts the technical scheme that a plurality of feeding ports 10 on one upper plate 9 are respectively provided with a number, and each number corresponds to one cage.
The invention has the further technical scheme that the middle part of the multipurpose guide tube 4 comprises a partition wall, so that excrement corresponding to the two cages can be separated.
The invention has the further technical scheme that the cage cleaning device also comprises a step of cleaning the cage, water washes the cage from the upper part, and the water is guided to the multipurpose guide pipe 4 along the guide wall 5 and then is cleaned, so that the cage cleaning device is quickly cleaned, and water is not accumulated on the ground.
Compared with the prior art, the invention adopting the technical scheme has the following beneficial effects:
can feed uniformly; the sanitation cleaning can be uniformly carried out; the space is not occupied; the activity can be measured, so that a new index is provided for measuring the activity of the mouse.
Drawings
To further illustrate the present invention, further description is provided below with reference to the accompanying drawings:
FIG. 1 is a schematic diagram of the inventive structure;
FIG. 2 is a schematic view of a stand-alone feeding configuration;
FIG. 3 is a schematic view of the overall structure;
FIG. 4 is a schematic view of a vertical riser in mid-section;
FIG. 5 is a side schematic view of a vertical riser;
FIG. 6 is a schematic view of the internal structure;
FIG. 7 is a relatively larger view of FIG. 6;
FIG. 8 is a block diagram of the base style mounting plate and threaded hole;
FIG. 9 is a cross-sectional view of the multipurpose guide tube and vertical riser;
wherein: 1. a base; 2. a fecal tube; 3. arranging the pipes in layers; 4. a multipurpose guide tube; 5. a guide wall; 6. a first sensor; 7. a second sensor; 8. a vertical riser; 9. an upper plate; 10. feeding ports; 11. a cage; 12. fixing the introducing pipe; 13. a groove; 14. a squirrel cage body opening; 15. a hand-held groove; 16. a bottom; 17. a body; 18. a bottle; 19. a handle or a camera; 20, a sensor; 21. connecting a transverse shaft; 22. a signal line; 23. heating wires; 24. a rearing cage groove; 25. a lower outlet; 26. a butt joint port; 27. a threaded hole; 28. and (7) mounting the plate.
Detailed Description
The present invention will be further illustrated with reference to the accompanying drawings and specific embodiments, which are to be understood as merely illustrative of the invention and not as limiting the scope of the invention. In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", "top", "bottom", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention. Furthermore, unless expressly stated or limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, as they may be fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
The patent provides a plurality of parallel schemes, and different expressions belong to an improved scheme based on a basic scheme or a parallel scheme. Each solution has its own unique features.
The first scheme is as follows:
the first embodiment is as follows: with reference to all of the accompanying drawings;
the micro-control squirrel cage for the activity of the microbiological medical test is characterized in that the cleaning device comprises a base 1 or a bottom 16; the multifunctional excrement collecting device also comprises a vertical stand pipe 8, more than one multipurpose guide pipe 4 is arranged on the vertical stand pipe 8, the multipurpose guide pipes 4 are circularly distributed on the vertical stand pipe 8, the lower part of each multipurpose guide pipe 4 is closed, and the closed part extends out of the excrement pipe 2; a circle of connecting transverse shafts 21 are arranged on the multipurpose guide pipe 4 in an upward mode, a circle of guide walls 5 are fixed on the connecting transverse shafts 21, and openings below the guide walls 5 guide openings above the multipurpose guide pipe 4;
a fixed plate is arranged on the vertical pipe 8, and a sensor is arranged on the fixed plate;
the cage body is placed on the fixing plate and presses the sensor;
the sensor is capable of measuring the frequency of activity of the organisms in the cage;
both cages were placed on a level. The technical scheme of the invention has the following substantial technical effects and the realization process thereof: A. a method for measuring the activity of a mouse in a biomedical test is characterized in that the micro-control mouse cage is utilized;
a plurality of mice are experimental mice;
the more each mouse moves, the higher the micro-vibration times and frequency of the mouse cage detected by the vibration sensor; and (h) =. Counting the time and frequency of the triggering of the vibration sensor; the activity of the mouse can be evaluated in an index way; B. the three-dimensional feeding can simultaneously feed a plurality of groups of mice.
Creatively, the above effects exist independently, and the combination of the above results can be completed by a set of structure.
It should be noted that the modules of this patent belong to the integration of the modules of the prior art, and do not relate to new modules.
Example two: as a further improvement or in parallel or alternatively independently, the sensor is a vibration sensor; the vibration sensor is connected with the central control system in a communication mode. The technical scheme of the invention has the following substantial technical effects and the realization process: the vibration sensor is selected from a SW18015PPSU vibration sensor or a patch type vibration sensor. The more triggers the more active.
Example three: as a further development, either in parallel or alternatively independently, the bottom of the cage comprises a recess, in correspondence with the position of the sensor on the fixed plate, in engagement with the sensor. The technical scheme of the invention has the following substantial technical effects and the realization process: the squirrel cage is fixed by matching with the sensor, and the vibration and the activity can be measured at any time.
Example four: as a further development or a parallel solution or an optional independent solution, the bottom of the squirrel cage is a grid; the rat excrement is guided to the multipurpose guide pipe 4 and then guided to the excrement pipe 2 to be collected. The technical scheme of the invention has the following substantial technical effects and the realization process: excrement does not need to be cleaned specially, and the excrement can be automatically separated integrally.
Example five: as a further development or in a juxtaposition or alternatively independently, the base 11 is of flange construction, the flange comprising a ring of threads and a corresponding mounting plate comprising a plurality of threaded holes arranged in juxtaposition thereon. The technical scheme of the invention has the following substantial technical effects and the realization process: meanwhile, a plurality of groups of micro-control squirrel cages can be arranged.
Example six: as a further development or a side-by-side or alternatively a stand-alone solution, the cage comprises a cage trough 24, the cage body comprises a fixed inlet duct 12, the fixed inlet duct 12 leads into the cage trough 24, the fixed inlet duct 12 extends as an inclined duct which can be docked to the fixed inlet duct 12 in a docking port 26 in the vertical upright 8; the fixed inlet pipe 12 is communicated with the feeding port 10 on the upper plate 9 above; each feeding port 10 is capable of holding material down and directing the material through a stationary intake tube 12 into a cage tub 24. The technical scheme of the invention has the following substantial technical effects and the realization process: can be uniformly fed through the upper part.
Example seven: as a further development or in a parallel or optionally independent solution, the vibration sensor is communicatively connected to a signal line 22, which is connected to the central control unit; the signal line 22 is located in the vertical riser 8; a fixed lead-in pipe 12 is also located in the vertical riser 8.
Example eight: as a further improvement scheme or a parallel scheme or an alternative independent scheme, the base is square, and moving wheels are contained below the square base. The technical scheme of the invention has the following substantial technical effects and the realization process: the whole mouse is convenient to move.
Example nine: as a further development, either in parallel or alternatively independently, the vertical riser 8 also contains heating wires 23; the heating wire 23 can be electrified to heat the mouse cage.
Scheme II:
example ten: as a further development or a parallel development or alternatively an independent development, a method for the automated cleaning and precise feeding of mice in a three-dimensional manner in a medical laboratory is characterized in that the cleaning device comprises a base 1 or a bottom 16; the multifunctional excrement collecting device also comprises a vertical stand pipe 8, more than one multipurpose guide pipe 4 is arranged on the vertical stand pipe 8, the multipurpose guide pipes 4 are circularly distributed on the vertical stand pipe 8, the lower part of each multipurpose guide pipe 4 is closed, and the closed part extends out of the excrement pipe 2; a circle of connecting transverse shafts 21 are arranged on the multipurpose guide pipe 4 in an upward mode, a circle of guide walls 5 are fixed on the connecting transverse shafts 21, and openings below the guide walls 5 guide openings above the multipurpose guide pipe 4;
the cage comprises a cage trough 24, the cage body comprises a fixed ingress pipe 12, the fixed ingress pipe 12 is guided into the cage trough 24, the fixed ingress pipe 12 extends out to form an inclined pipeline, and the inclined pipeline can butt against the fixed ingress pipe 12 in a butt joint 26 on the vertical pipe 8; the fixed inlet pipe 12 is communicated with the feeding port 10 on the upper plate 9 above; each feeding port 10 can be used for placing materials downwards and guiding the materials into a feeding cage groove 24 through a fixed inlet pipe 12;
two cages are placed at one height; the cage body is placed on the fixing plate and presses the sensor;
the cage is semicircular overall, and an arc-shaped groove 13 in the middle of the semicircle is matched with the vertical pipe 8; the cage body comprises a hand-holding groove 15, the hand-holding groove 15 can be used for holding a bottle 18, and the mouth of the bottle 18 can correspond to a feeding cage groove 24;
each feeding port 10 can be used for placing materials downwards and guiding the materials into a feeding cage groove 24 through a fixed inlet pipe 12; therefore, different drugs or microbial agents can be fed to a plurality of squirrel cages in a differentiated mode for comparison; people do not need to look for numbers and feed one by one, and all accurate operations can be realized on one upper plate 9;
the bottom of the squirrel cage is provided with a grid; the white rat excrement is guided into the multipurpose guide pipe 4 and then guided into the excrement pipe 2 to be collected;
the space is saved in three-dimensional breed and experiment, can realize space make full use of in local space.
Example eleven: as a further improvement scheme or a parallel scheme or an alternative independent scheme, two cages are placed at a height and are arranged in parallel, and for the same breeding environment, the white rat excrement led out by the multi-purpose guide pipes 4 corresponding to the two cages is guided into the multi-purpose guide pipe 4 and then guided into the excrement pipe 2; for individual collection for pathological analysis of the feces.
Example twelve: as a further development or in a side-by-side or alternatively independent solution, the feeding ports 10 on one upper plate 9 are each numbered, one for each cage.
Example thirteen: as a further improvement or a side-by-side or alternative independent solution, the multipurpose guide tube 4 comprises a partition wall in the middle, which can separate the feces of the two cages.
Example fourteen: as a further development or in a side-by-side or alternatively independent solution, it also comprises the step of washing the device, the cage being washed from above by water, which is guided along the guide wall 5 to the multipurpose guide tube 4 and then cleaned, achieving a quick cleaning without accumulating water on the ground.
Creatively, the above effects exist independently, and the combination of the above results can be completed by a set of structure.
The technical effect that above structure was realized is realized clearly, if do not consider additional technical scheme, this patent name can also be a three-dimensional squirrel cage. Some details are not shown in the figures.
It should be noted that the plurality of schemes provided in this patent include their own basic schemes, which are independent of each other and are not restricted to each other, but they may be combined with each other without conflict, so as to achieve a plurality of effects.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are intended to illustrate the principles of the invention, but that various changes and modifications may be made without departing from the spirit and scope of the invention, and the invention is to be limited to the embodiments described above.
Claims (10)
1. The micro-control squirrel cage for the activity of the microbiological medical test is characterized in that the cleaning device comprises a base (1) or a bottom (16); the multifunctional excrement collecting device also comprises a vertical stand pipe (8), more than one multipurpose guide pipe (4) is arranged on the vertical stand pipe (8), the multipurpose guide pipes (4) are annularly distributed on the vertical stand pipe (8) for one circle, the lower part of each multipurpose guide pipe (4) is closed, and the closed part extends out of the excrement pipe (2); a circle of connecting transverse shafts (21) are arranged upwards on the multipurpose guide pipe (4), a circle of guide walls (5) are fixed on the connecting transverse shafts (21), and an opening below the guide walls (5) leads to an opening above the multipurpose guide pipe (4);
a fixed plate is arranged on the vertical pipe (8), and a sensor is arranged on the fixed plate;
the cage body is placed on the fixing plate and presses the sensor;
the sensor is capable of measuring the frequency of activity of the organisms in the cage;
both cages were placed on a level.
2. The micro-control squirrel cage for the activity of the microbiological medical test as claimed in claim 1, wherein the sensor is a vibration sensor; the vibration sensor is connected with the central control system in a communication mode.
3. The micro-control squirrel cage for the activity of the biomedical tests as claimed in claim 1, wherein the position of the bottom of the squirrel cage corresponding to the sensor on the fixing plate comprises a groove which is matched with the sensor.
4. The micro-control squirrel cage for the activity of the microbiological medical test as claimed in claim 1, wherein the bottom of the squirrel cage is a grid; the white rat excrement is guided to the multipurpose guide pipe (4) and then guided to the excrement pipe (2) to be collected.
5. The micro-control cage for the activity of the biomedical tests according to claim 1, characterized in that the base (11) is of a flange structure, the flange comprises a circle of screw thread and a corresponding mounting plate, the mounting plate comprises a plurality of screw holes, and the screw holes are arranged in parallel on the mounting plate.
6. The micro-mouse cage for controlling activity in biomedical tests according to claim 1, characterized in that it comprises a housing groove (24), the cage body comprises a fixed introduction pipe (12), the fixed introduction pipe (12) is guided into the housing groove (24), the fixed introduction pipe (12) extends as an inclined pipe, the inclined pipe can abut against the fixed introduction pipe (12) in the abutting opening (26) of the vertical pipe (8); the fixed lead-in pipe (12) is communicated with a feeding port (10) on the upper plate (9) above; each feeding port (10) is capable of holding material down and guiding the material through a fixed inlet pipe (12) to a feeding cage trough (24).
7. The micro-control squirrel cage for the activity of the microbiological medical test as claimed in claim 2, wherein the vibration sensor is communicatively connected to a signal line (22) connected to the central control section; the signal wire (22) is positioned in the vertical riser (8); a fixed lead-in pipe (12) is also located in the vertical riser (8).
8. The micro-control squirrel cage for the activity of the biomedical tests, as claimed in claim 2, wherein the base is square and comprises moving wheels under the square base.
9. The micro-mouse cage for the activity of the microbiological medical test according to claim 7, characterized in that the vertical pipe (8) further comprises a heating wire (23); the heating wire (23) can be electrified to heat the squirrel cage.
10. A method for determining the activity of mice in biomedical tests, characterized in that a micro-mouse cage according to any of the claims 1 to 9 is used;
a plurality of mice are experimental mice;
the more each mouse moves, the higher the micro-vibration times and frequency of the mouse cage detected by the vibration sensor;
counting the time and frequency of the triggering of the vibration sensor; the activity of the mouse can be evaluated in an index way.
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