CN114403019A

CN114403019A - Small animal feeding device for contrast experiment

Info

Publication number: CN114403019A
Application number: CN202210053958.1A
Authority: CN
Inventors: 陈弈辉; 韩奔; 孙力华; 刘星宇; 肖卫东; 谢会超; 汤玲一; 杜广胜
Original assignee: Second Affiliated Hospital Army Medical University
Current assignee: Second Affiliated Hospital Army Medical University
Priority date: 2022-01-18
Filing date: 2022-01-18
Publication date: 2022-04-29
Anticipated expiration: 2042-01-18
Also published as: CN114403019B

Abstract

The invention provides a small animal feeding device for a contrast experiment, which comprises a box body and a box cover, wherein the box body is at least divided into a feeding chamber and a sampling chamber which are arranged in an up-down stacked mode; at least two feeding boxes arranged side by side are arranged in the feeding chamber, and rotating cages corresponding to the feeding boxes are arranged in the sampling chamber and used for bearing the small animals. The feeding boxes are arranged in the same feeding space, so that the independent feeding and comparative observation of each experimental unit are realized under the same experimental environment; the rotary cage is used for supporting the small animals, the buffer storage bin arranged in the rotary cage is used as a temporary storage space for excrement and/or food residues of the small animals, and the small animals are unloaded into the receiving plate to be discharged after the rotary cage rotates for a certain angle, so that the self-cleaning of the living environment of the small animals is realized; the small animal is prompted to independently defecate or urinate by means of external environment stimulation and the like, and the small animal is accepted through the clean buffer storage bin, and then the rotating cage is reversed to discharge the defecate and the urinate into different sampling boxes respectively, so that sample interference is avoided.

Description

Small animal feeding device for contrast experiment

Technical Field

The invention relates to the technical field of medical instruments, in particular to a small animal feeding device for a contrast experiment.

Background

Laboratory mice (including large mice of various strains of laboratory animals) refer to special laboratory animals that are commonly used as subjects or materials in the fields of life sciences (physiology, medicine, pharmacy, etc.) for production, teaching, and research. The contribution of the experimental mouse can be avoided in medicine, vaccine and biological medicine production, surgical operation practice, quality inspection and safety evaluation of new medicines, foods and medicines, research of life science and the like, and the experimental mouse can be said to be a human candidate and a live reagent for scientific research. When experimental research is carried out on experimental mice, a plurality of groups of comparison experiments are usually required, and the common rearing cage can only rearing the experimental mice and can not directly carry out experimental research.

Disclosure of Invention

Aiming at the defects in the prior art, the invention provides a small animal feeding device for a contrast experiment, which aims to solve the technical problem that the existing small animal feeding cage cannot be directly used for the contrast experiment.

In order to achieve the purpose, the invention is realized by the following technical scheme:

the invention provides a small animal feeding device for a contrast experiment, which comprises a box body and a box cover, and is characterized in that at least a first clapboard is arranged in the box body to at least divide the box body into a feeding chamber and a sampling chamber which are arranged in an up-down stacked manner, and the feeding chamber is positioned above the sampling chamber; at least two feeding boxes which are arranged side by side are arranged in the feeding chamber, and the bottom of each feeding box is provided with an opening; a rotating cage corresponding to the feeding box is arranged in the sampling chamber, and the upper part of the rotating cage penetrates through the first partition plate and is embedded into the bottom opening of the feeding box so as to be used for bearing the small animals;

the shaft center of the rotating cage is provided with a rotating shaft, a separating sheet is connected between the outer wall of the rotating shaft and the inner wall of the rotating cage, and at least two separating sheets are uniformly distributed around the periphery of the rotating shaft so as to at least divide the interior of the rotating cage into two buffer bins; the outer wall of the rotating cage is provided with a plurality of slotted holes, and the slotted holes are communicated with the cache bin;

a material receiving plate is arranged below the rotating cage, and the material receiving plate is obliquely arranged and supported by the box body; the sampling box is further arranged above the lowest position of the material receiving plate, and a sampling opening is formed in the side wall, close to the sampling box, of the sampling chamber, so that the sampling box can be taken and placed conveniently.

Furthermore, one side of the rotating cage is provided with detection holes, and the detection holes correspond to the cache bins one by one; still be equipped with excrement and urine inductive probe on the support to see through the inspection hole detects the excrement and urine memory space in the buffer storage storehouse.

Furthermore, two ends of the rotating shaft are respectively rotatably connected with the same support, one end of the rotating shaft is also in transmission connection with a motor, and the motor is fixedly connected with the support; the support below still is equipped with the mounting panel, just be equipped with weighing sensor between the bottom plate of support and the mounting panel.

Furthermore, still be equipped with a plurality of liveness alarms on the box, liveness alarm and weighing sensor one-to-one.

Further, the method also comprises an activity alarm control method:

the weighing sensor collects mass data for multiple times in unit time and transmits the mass data to the controller;

the controller calculates the activity value of the small animal based on the fluctuation frequency of the mass data in unit time returned by the weighing sensor, and when the activity value exceeds a preset warning value, the controller sends an alarm instruction to the activity alarm;

and the activity alarm makes an alarm response after receiving the alarm instruction.

Furthermore, a second partition plate is further arranged in the box body, and the sampling chamber is clamped between the first partition plate and the second partition plate; the surface of the second baffle plate is provided with a material receiving port, and the material receiving port is positioned below the lowest position of the material receiving plate; connect the below of material mouthful to be equipped with and collect the box, collect box and box sliding connection.

Furthermore, a cleaning unit and a drying unit are further arranged above the highest position of the material receiving plate, the cleaning unit is used for washing the outer wall of the rotating cage and the inner wall of the cache bin, and the drying unit is used for drying the outer wall of the rotating cage and the inner wall of the cache bin.

Furthermore, a third partition plate is arranged below the second partition plate, the third partition plate divides the bottom space of the box body into a collection chamber and a warm water chamber, the collection box is arranged in the collection chamber, a warm water supply device is arranged in the warm water chamber, and the warm water supply device is communicated with the cleaning unit; the side wall inner dish of raising the room is equipped with warm water pipe, warm water pipe also communicates with warm water feeding device.

Further, the top end of the feeding box is open; a feeding trough is arranged on the inner wall of the feeding box, and a feeding mechanism is arranged on the box cover and used for adding food into the feeding trough through an opening at the top end of the feeding box; the inner wall of the breeding box is also provided with a water tank, and the box cover is also provided with a water supplementing mechanism for adding drinking water into the water tank through the top opening of the breeding box.

Furthermore, the bottom surface of the box cover is also provided with hooks capable of sliding along the length direction of the feeding box, and the number and the positions of the hooks are in one-to-one correspondence with the feeding box so as to hook the infusion bags.

According to the technical scheme, the invention has the beneficial effects that:

1) the feeding boxes are arranged in the same feeding space, so that the independent feeding and comparative observation of each experimental unit are realized under the same experimental environment;

2) the rotary cage is used for supporting the small animals, the buffer storage bin arranged in the rotary cage is used as a temporary storage space for excrement and/or food residues of the small animals, and after the rotary cage rotates for a certain angle, the excrement and/or the food residues are discharged into the material receiving plate to be discharged, so that the self-cleaning of the living environment of the small animals is realized;

4) the small animals are prompted to independently defecate or urinate by means of external environment stimulation and the like and are received by the clean buffer storage bin, then the rotating cage rotates reversely for a certain angle, the defecate or the urine is discharged into the sampling box, the sampling box is replaceable, and one sampling box is only used for receiving one of the defecate or the urine, so that sample interference is avoided;

3) the weight change of the small animal is measured by a weighing sensor arranged at the bottom of the rotating cage, so that an experimenter can know the health condition of the small animal based on the weight change of the small animal, and meanwhile, the liveness condition of the small animal can be judged based on the fluctuation frequency of the measured weight in unit time, and an alarm is sent to the experimenter in due time;

5) the bottom of the feeding device is provided with the warm water supply unit to provide water heating temperature control for the feeding chamber, provide flushing liquid for the sampling chamber and add disinfectant into the flushing liquid so as to complete the cleaning and disinfection work of the rotating cage;

6) the collection of excrement, food waste or cleaning fluid and the like is completed through a collection box arranged below the rotating cage, so that the centralized treatment of experimenters is facilitated.

Drawings

In order to more clearly illustrate the detailed description of the invention or the technical solutions in the prior art, the drawings that are needed in the detailed description of the invention or the prior art will be briefly described below. Throughout the drawings, like elements or portions are generally identified by like reference numerals. In the drawings, elements or portions are not necessarily drawn to scale.

FIG. 1 is a schematic perspective view of a small animal breeding apparatus for comparative experiments;

FIG. 2 is a schematic view of the forward rotation of the cage;

FIG. 3 is a schematic diagram of the tumble rotation;

FIG. 4 is a schematic perspective view of the rotating cage and the stand;

FIG. 5 is a schematic view showing an internal structure of a small animal breeding apparatus for a comparative experiment;

FIG. 6 is a schematic view of the mounting of a load cell;

FIG. 7 is an enlarged view taken at A in FIG. 6;

reference numerals:

1-box body, 2-box cover, 3-feeding box, 4-rotating cage, 5-bracket, 6-mounting plate, 7-cleaning unit, 8-drying unit and 9-material receiving plate;

11-a first partition plate, 12-a second partition plate, 13-a third partition plate, 14-a feeding chamber, 15-a sampling chamber, 16-a collecting chamber, 17-a warm water chamber, 18-a box door, 19-a warm water pipe, 31-air holes, 41-a rotating shaft, 42-a partition plate, 43-a buffer storage bin, 44-a slotted hole, 45-a detection hole, 51-a bottom plate, 52-a limiting hole, 53-a motor, 54-a feces sensing probe, 61-a weighing sensor and 62-a limiting rod;

121-material receiving port, 151-using port, 152-sampling box and 161-collecting box.

Detailed Description

Embodiments of the present invention will be described in detail below with reference to the accompanying drawings. The following examples are only for illustrating the technical solutions of the present invention more clearly, and therefore are only examples, and the protection scope of the present invention is not limited thereby.

Referring to fig. 1-3, the small animal raising apparatus for comparative experiments provided by the present invention comprises a case body 1 and a case cover 2, wherein the case cover 2 is detachably connected to the case body 1, and a plurality of environmental regulation and/or environmental data monitoring units are disposed in the case cover 2 and detachably designed to facilitate maintenance of various instruments in the case cover 2. At least a first partition plate 11 is arranged in the box body 1 so as to at least divide the box body 1 into a feeding chamber 14 and a sampling chamber 15 which are arranged in an up-down stacked mode, and the feeding chamber 14 is located above the sampling chamber 15. The feeding room 14 is used for feeding, infusing and observing a plurality of small animals (such as laboratory mice, rabbits and the like), and provides the same environmental conditions such as temperature, humidity, illumination, ventilation, oxygen concentration and the like for each small animal; the sampling chamber 15 is used for sampling excrement, measuring body weight, and collecting and processing excrement and food residues of each small animal. Wherein, the case lid 2 is provided with one or more of humiture appearance, humidification unit, temperature regulation unit, disinfection unit, trades wind unit and illumination unit. At least two feeding boxes 3 arranged side by side are arranged in the feeding chamber 14, and the bottoms of the feeding boxes 3 are open; be equipped with in the sampling chamber 15 and raise 3 position correspondences of box rotating cage 4, rotating cage 4 outline is the cylinder shape, the bottom opening that first baffle 11 and embedding were raised box 3 is run through on the upper portion of rotating cage 4 axial lead to be used for bearing the weight of toy, the whole weight of toy is the bearing of rotating cage 4 promptly, and raise box 3 only restricts the toy activity space. Preferably, a box door 18 is arranged on one side of the feeding chamber 14, the box door 18 and the feeding box 3 are both made of transparent materials so as to facilitate observation, a movable door is hinged on one side of the feeding box 3 facing the box door 18 so as to facilitate taking and placing of small animals, and air holes 31 are formed in the peripheral wall of the feeding box 3 so as to facilitate air circulation. In order to better simulate the living environment of the small animals, a window shade can be arranged outside the box door 18.

Specifically, referring to fig. 3-4, a rotating shaft 41 is disposed at the axis of the rotating cage 4, a separating plate 42 is connected between the outer wall of the rotating shaft 41 and the inner wall of the rotating cage 4, at least two separating plates 42 are uniformly distributed around the periphery of the rotating shaft 41, so as to divide the interior of the rotating cage 4 into at least two buffer bins 43; the outer wall of the rotating cage 4 is provided with a plurality of slotted holes 44, and the slotted holes 44 are communicated with the buffer storage bin 43 so as to facilitate the passing of excrement of small animals; a receiving plate 9 is arranged below the rotating cage 4, and the receiving plate 9 is obliquely arranged and supported by the box body 1 so as to be used for receiving excrement of small animals which are separated from the buffering bin 43. A sampling box 152 is further arranged above the lowest position of the material receiving plate 9, and a sampling opening 151 is formed in one side wall of the sampling chamber 15, which is close to the sampling box 152, so that the sampling box 152 can be conveniently taken and placed. It is worth noting that each rotating cage all corresponds to a sampling box, when a buffer bin is selected as an excrement sample collecting chamber, namely the buffer bin rotates anticlockwise to move to the position right below the small animal, after the small animal is stimulated to excrete through an external environment, one of the partition sheets rotating clockwise to the buffer bin inclines towards the sampling box, so that the collected excrement sample is unloaded into the sampling box, and then the experimental sample can be obtained only by taking out the sampling box. For easy understanding, with reference to fig. 2, when the rotating cage is self-cleaned, the rotating cage needs to rotate counterclockwise in the whole process; with reference to fig. 2-3, when a sample is collected, the buffer bin needs to be replaced by rotating counterclockwise first, and then the sample is rotated clockwise after being obtained.

On one hand, the invention realizes the independent feeding and comparative observation of each experimental unit under the same experimental environment by arranging a plurality of feeding boxes in the same feeding space; on the other hand, the buffer storage bin arranged in the rotating cage is used as a temporary storage space for the excrement and/or food residues of the small animals, and the excrement and/or the food residues are discharged into the material receiving plate to be discharged after the rotating cage rotates for a certain angle, so that the self-cleaning of the living environment of the small animals is realized; on the other hand, the small animals are prompted to independently defecate or urinate by means of external environment stimulation and the like and are accommodated by a clean buffer storage bin, then the rotating cage rotates reversely for a certain angle, the defecate or the urine is discharged into the sampling box, the sampling box is replaceable, and one sampling box is only used for accommodating one of the defecate or the urine, so that sample interference is avoided; on the other hand, along with the rotation of the rotating cage, the small animals need to run to a certain extent to match the action of the rotating cage, and the rotating speed of the rotating cage is reasonably set, so that certain exercise training can be carried out on the small animals, and the healthy feeding of the small animals is facilitated.

As a further improvement to the above solution, please refer to fig. 4 and 6, two ends of the rotating shaft 41 are rotatably connected to the same bracket 5, one end of the rotating shaft 41 is also in transmission connection with a motor 53, and the motor 53 is fixedly connected to the bracket 5; still be equipped with mounting panel 6 below support 5, just be equipped with weighing sensor 61 between bottom plate 51 of support 5 and mounting panel 6. It is to be noted that the receiving plate 9 is mounted directly on the box 1 without coming into contact with the support 5 or the rotating cage 4, so as to avoid interfering with the operation of the load cell 61. The weighing sensor 61 is used for weighing the mass of the support 5, the rotating cage 4 and the small animals on the upper part of the rotating cage 4, and because the mass of the support 5 and the rotating cage 4 is quantitative, only the weight of the small animals is influenced by the feeding, the movement and the excretion of the small animals to generate fluctuation, namely after the rotating cage 4 discharges the excretion in time, the weighing sensor 61 can measure the current actual weight of the small animals, and the change of the weight of the small animals in the preset time period can be obtained by measuring for multiple times in the preset time period. It should be noted that the load cell 61 does not operate when the rotation cage 4 rotates, so as to avoid the unbalanced force generated when the rotation cage 4 rotates causing the detection value of the load cell 61 to fluctuate greatly. Preferably, referring to fig. 6-7, the bottom plate 51 is provided with a limiting hole 52 at four corners, a limiting rod 62 is disposed at a position of the top surface of the mounting plate 6 corresponding to the limiting hole 52, and the limiting hole 52 is sleeved on the periphery of the limiting rod 62 to reduce the swing of the bracket 5 and the rotating cage 4 by means of the limiting rod 62.

The rotating cage 4 is driven to rotate by the motor 53, so that only one buffer bin 43 covers the moving space of the small animal at the same time, namely the fan-shaped area of the buffer bin 43 is not smaller than the inner diameter of the feeding box 3 as shown in fig. 2, and further only one buffer bin 43 can be used for receiving excrement of the small animal at the same time; and because the rotating cage 4 is cylindrical, the rest of the buffer bins 43 are all in an inclined state, and the discharged matters in the bins can all be separated out through the slotted holes 44 on the surfaces of the bins. Obviously, the feeding device further comprises a controller, and the controller is electrically connected with the motor 53 to control the starting, stopping and rotating speed of the motor 53; the controller is also electrically connected with the weighing sensor 61 to receive the detection data returned by the weighing sensor 61, and the controller can send the detection data to a display terminal or a server for the experimenter to look up.

As a further improvement to the above scheme, please refer to fig. 3, a side sealing plate of the rotating cage 4 is provided with a detection hole 45, and the detection hole 45 is communicated with the cache bin 43; each buffer bin 43 is correspondingly provided with a detection hole 45; the bracket 5 is also provided with an excrement sensing probe 54 so as to detect the excrement storage amount in the buffer storage bin 43 through the detection hole 45; the fecal induction probe 54 is also electrically connected with the controller to transmit the detected fecal storage information back to the controller, which is convenient for the controller to determine the time for replacing the buffer bin. The excrement sensing probe 54 can be a telescopic camera, when the rotating cage 4 rotates to the position where the detection hole 45 corresponds to the camera, the camera extends into the buffer storage bin 43 through the detection hole 45 to directly obtain image information and transmits the image information back to the controller, and the controller judges whether the motor 53 is started to rotate the rotating cage 4 or not so as to replace the buffer storage bin 43; the fecal induction probe 54 can also be an odor sensor, when the concentration of odor generated by feces reaches a preset value, the odor sensor sends a fecal treatment signal to the controller, and the controller receives the fecal treatment signal, namely, controls the motor 53 to rotate the rotating cage 4, so as to replace the buffer bin 43. The excrement cleaning work in the rotating cage 4 is automatically completed through the cooperation of the excrement sensing probe 54 and the controller. Or, the buffer bin can be controlled to be automatically replaced according to a certain rule by setting a program, and the preset program can be combined with the excrement sensing probe to carry out combined control. Obviously, the rotation of the cage is manually controlled by the laboratory operator on site when taking samples.

As a further improvement to the above scheme, still be equipped with a plurality of liveness alarms (not shown in the figure) on the box 1, liveness alarm and raise box 3 one-to-one, and every liveness alarm is equallyd divide and is connected with the controller electricity respectively. Specifically, the control principle and the control method of the liveness alarm are as follows:

s1, the weighing sensor 61 collects mass data for multiple times in unit time and transmits the mass data to the controller; it should be noted that, in the unit time, the rotating cage 4 does not rotate, so as to avoid that the unbalance force generated when the rotating cage 4 rotates causes the detection value of the weighing sensor 61 to fluctuate greatly;

s2, calculating an activity value of the small animal by the controller based on the fluctuation frequency of the mass data in unit time returned by the weighing sensor 61, and sending an alarm instruction to an activity alarm by the controller when the activity value exceeds a preset alarm value; the method specifically comprises the following substeps:

s21, when the activity value is higher than a first preset warning value, the controller sends a first alarm instruction to the activity alarm, and the first alarm instruction is an extreme activity alarm instruction; because the rotating cage 4 does not rotate, each action of the small animal applies an acting force to the weighing sensor 61 through the rotating cage 4 and the support 5, the detection value of the weighing sensor 61 changes, the fluctuation frequency of data in unit time (wherein the data with smaller fluctuation can be filtered) can be counted to reflect the movement frequency of the small animal in the unit time, the higher the movement frequency is, the more active the small animal is, if the small animal is extremely active, stimulation factors may exist in the small animal body, or the living environment is inappropriate (such as oxygen deficiency), the experimenter needs to be reminded to check the small animal in the feeding box 3 in time, and a first alarm instruction is sent;

s22, when the activity values recorded by the controller are all lower than a second preset warning value in a preset period, the controller sends a second alarm instruction to the activity alarm, and the second alarm instruction is an endangered alarm instruction (or an extremely inactive alarm instruction); if the small animal is immobile for a long time or the action amplitude is small, the body of the small animal may have pathological change factors or may have extremely severe environment (for example, the environment temperature is too low due to temperature control failure), the laboratory staff needs to be reminded to immediately check the small animal, and a second alarm instruction is sent out;

and S3, the liveness alarm receives the alarm instruction and then gives an alarm response, such as sound and light alarm. In one embodiment, when the activity alarm receives the first alarm instruction, the yellow light can be emitted; when the activity alarm receives the second alarm instruction, the red light can be emitted.

As a further improvement to the above scheme, please refer to fig. 2, a second partition plate 12 is further disposed in the box body 1, and the sampling chamber 15 is sandwiched between the first partition plate 11 and the second partition plate 12; the surface of the second partition plate 12 is provided with material receiving ports 121, the material receiving ports 121 are located below the lowest position of the material receiving plates 9, obviously, only one material receiving port 121 may be provided, or a plurality of material receiving ports 121 may be provided and correspond to the material receiving plates one to one; the collecting box 161 is arranged below the material receiving port 121, the collecting box 161 is connected with the box body 1 in a sliding mode, and excrement, food residues and cleaning liquid of the small animals in the rearing box 3 are collected through the collecting box 161.

As a further improvement to the above scheme, please refer to fig. 2 and 4, a cleaning unit 7 and a drying unit 8 are further disposed above the highest position of the material receiving plate 9, the cleaning unit 7 is configured to wash the outer wall of the rotating cage 4 and the inner wall of the buffer bin 43, the washing liquid can clean the inner wall of the buffer bin 43 through the slot 44 on the surface of the rotating cage 4, and the drying unit 8 is configured to dry the outer wall of the rotating cage 4 and the inner wall of the buffer bin 43; the cleaning unit 7 and the drying unit 8 are respectively electrically connected with the controller. Mainly washes urine in excrement, dries to make the small animal obtain a clean and dry ground of falling the foot, and can add disinfectant in the washing liquid to accomplish the washing of rotating cage, disinfection work. Preferably, a third partition plate 13 is further arranged below the second partition plate 12, the third partition plate 13 divides the bottom space of the tank 1 into a collection chamber 16 and a warm water chamber 17, the collection box 161 is arranged in the collection chamber 16, and a warm water supply device is arranged in the warm water chamber 17 and is communicated with the cleaning unit 7 to supply the cleaning solution to the cleaning unit 7; a warm water pipe 19 is arranged on the inner disc of the side wall of the feeding chamber 14, and the warm water pipe 19 is also communicated with a warm water supply device, namely the temperature of the feeding chamber 14 is adjusted by means of water heating; the warm water supply device is also electrically connected with the controller.

As a further improvement to the above scheme, the top end of the feeding box 3 is opened; a feeding trough is arranged on the inner wall of the feeding box 3, and a feeding mechanism is arranged on the box cover 2 and used for adding food into the feeding trough through an opening at the top end of the feeding box 3; still be equipped with the basin on raising 3 inner walls of box, still be equipped with moisturizing mechanism on case lid 2 and be used for through raising 3 top openings of box and add the drinking water to the basin.

As a further improvement to the scheme, the bottom surface of the box cover 2 is further provided with hooks capable of sliding along the length direction of the feeding box 3, and the number and the positions of the hooks are in one-to-one correspondence with the feeding box 3 so as to hook infusion bags and facilitate infusion operation on the small animals. Preferably, the bottom surface of the box cover 2 is provided with a resistance slide rail (based on the principle of a slide wire resistor), the hook can be pulled to slide by a transfusion conduit connected to the body of the small animal when the small animal moves, different resistance values are generated when the hook slides, the change frequency of the resistance values in unit time can reflect the movement frequency of the small animal in the unit time, and then the activity value of the small animal is calculated and can be used together with an activity value alarm. It should be noted that the infusion catheter needs to be a tube body which is resistant to bite and flexible, for example, "a spring sheath using an electric stove wire as the infusion catheter" mentioned in the patent of chinese invention of patent No. CN102397114A can be used to protect the safety of the infusion catheter, prevent the catheter from falling off or winding around the small animal due to the overlong catheter, prevent the small animal from biting the tube and affecting the infusion, and automatically adjust the length to adapt to the moving distance of the experimental small animal through the elasticity of the spring.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention, and they should be construed as being included in the following claims and description.

Claims

1. The small animal feeding device for the contrast experiment comprises a box body (1) and a box cover (2), and is characterized in that at least a first partition plate (11) is arranged in the box body (1) to at least divide the box body (1) into a feeding chamber (14) and a sampling chamber (15) which are arranged in an up-down stacked mode, and the feeding chamber (14) is located above the sampling chamber (15); at least two feeding boxes (3) arranged side by side are arranged in the feeding chamber (14), and the bottom of each feeding box (3) is provided with an opening; a rotating cage (4) corresponding to the feeding box (3) is arranged in the sampling chamber (15), and the upper part of the rotating cage (4) penetrates through the first partition plate (11) and is embedded into the bottom opening of the feeding box (3) so as to be used for bearing the small animals;

a rotating shaft (41) is arranged at the axis of the rotating cage (4), a separating sheet (42) is connected between the outer wall of the rotating shaft (41) and the inner wall of the rotating cage (4), at least two separating sheets (42) are uniformly distributed around the periphery of the rotating shaft (41) so as to at least divide the inside of the rotating cage (4) into two buffer bins (43); the outer wall of the rotating cage (4) is provided with a plurality of slotted holes (44), and the slotted holes (44) are communicated with the cache bin (43);

a material receiving plate (9) is arranged below the rotating cage (4), and the material receiving plate (9) is obliquely arranged and supported by the box body (1); a sampling box (152) is further arranged above the lowest position of the material receiving plate (9), and a sampling opening (151) is formed in one side wall, close to the sampling box (152), of the sampling chamber (15), so that the sampling box (152) can be conveniently taken and placed.

2. The small animal feeding device for the comparative experiment as set forth in claim 1, wherein the rotating cage (4) is provided at one side thereof with detecting holes (45), the detecting holes (45) corresponding to the buffer bins (43) one by one; still be equipped with excrement and urine inductive probe (54) on support (5) to see through excrement and urine memory space in inspection hole (45) detection buffer storage storehouse (43).

3. The small animal feeding device for the comparative experiment as set forth in claim 1 or 2, wherein both ends of the rotating shaft (41) are rotatably connected to the same bracket (5), respectively, and one end of the rotating shaft (41) is further connected to a motor (53) in a driving manner, and the motor (53) is fixedly connected to the bracket (5); support (5) below still is equipped with mounting panel (6), just be equipped with between bottom plate (51) of support (5) and mounting panel (6) weighing sensor (61).

4. The small animal feeding device for the contrast experiment according to claim 3, wherein a plurality of activity alarms are further arranged on the box body (1), and the activity alarms are in one-to-one correspondence with the weighing sensors (61).

5. The small animal feeding device for the comparative experiment as set forth in claim 4, further comprising an activity alarm control method of:

the weighing sensor (61) collects mass data for multiple times in unit time and transmits the mass data to the controller;

the controller calculates the activity value of the small animal based on the fluctuation frequency of the mass data in unit time returned by the weighing sensor (61), and when the activity value exceeds a preset warning value, the controller sends an alarm instruction to the activity alarm;

6. A small animal feeding device for comparative experiments according to claim 1, characterized in that a second partition (12) is further provided in the box body (1), and the sampling chamber (15) is sandwiched between the first partition (11) and the second partition (12); a material receiving port (121) is formed in the surface of the second partition plate (12), and the material receiving port (121) is located below the lowest position of the material receiving plate (9); connect the below of material mouth (121) to be equipped with and collect box (161), collect box (161) and box (1) sliding connection.

7. The small animal feeding device for the contrast experiment according to claim 6, wherein a cleaning unit (7) and a drying unit (8) are further arranged above the highest position of the material receiving plate (9), the cleaning unit (7) is used for washing the outer wall of the rotating cage (4) and the inner wall of the buffer bin (43), and the drying unit (8) is used for drying the outer wall of the rotating cage (4) and the inner wall of the buffer bin (43).

8. The small animal feeding device for the comparative experiment according to claim 7, wherein a third partition plate (13) is further provided below the second partition plate (12), the third partition plate (13) divides the bottom space of the housing (1) into a collection chamber (16) and a warm water chamber (17), the collection box (161) is provided in the collection chamber (16), a warm water supply device is provided in the warm water chamber (17), and the warm water supply device is communicated with the washing unit (7); the side wall inner dish of raising room (14) is equipped with warm water pipe (19), warm water pipe (19) also communicates with warm water feeding device.

9. The small animal feeding device for comparative experiments as claimed in claim 1, characterized in that the feeding box (3) is open at the top end; a feeding trough is arranged on the inner wall of the feeding box (3), and a feeding mechanism is arranged on the box cover (2) and used for adding food into the feeding trough through an opening at the top end of the feeding box (3); the water feeding box is characterized in that a water tank is further arranged on the inner wall of the feeding box (3), and a water supplementing mechanism is further arranged on the box cover (2) and used for adding drinking water into the water tank through an opening in the top end of the feeding box (3).

10. The small animal feeding device for the comparative experiment according to claim 9, wherein hooks capable of sliding along the length direction of the feeding box (3) are further arranged on the bottom surface of the box cover (2), and the number and the positions of the hooks are in one-to-one correspondence with the feeding box (3) so as to hook infusion bags.