CN116649239A - animal sleep deprivation device - Google Patents
animal sleep deprivation device Download PDFInfo
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- CN116649239A CN116649239A CN202210152428.2A CN202210152428A CN116649239A CN 116649239 A CN116649239 A CN 116649239A CN 202210152428 A CN202210152428 A CN 202210152428A CN 116649239 A CN116649239 A CN 116649239A
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- 241001465754 Metazoa Species 0.000 title claims abstract description 83
- 208000010340 Sleep Deprivation Diseases 0.000 title claims abstract description 71
- 230000004888 barrier function Effects 0.000 claims abstract description 42
- 238000001035 drying Methods 0.000 claims abstract description 27
- 230000002550 fecal effect Effects 0.000 claims abstract description 19
- 238000010171 animal model Methods 0.000 claims abstract description 17
- 210000002700 urine Anatomy 0.000 claims description 19
- 230000006399 behavior Effects 0.000 claims description 9
- 230000004297 night vision Effects 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 238000012544 monitoring process Methods 0.000 claims description 3
- 238000002474 experimental method Methods 0.000 description 11
- 230000006870 function Effects 0.000 description 7
- 230000003542 behavioural effect Effects 0.000 description 4
- 210000003608 fece Anatomy 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 241000283984 Rodentia Species 0.000 description 3
- 230000035622 drinking Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
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- 241000699666 Mus <mouse, genus> Species 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- 241000700159 Rattus Species 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 239000003651 drinking water Substances 0.000 description 2
- 235000020188 drinking water Nutrition 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 230000001965 increasing effect Effects 0.000 description 2
- 239000003595 mist Substances 0.000 description 2
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- 230000035882 stress Effects 0.000 description 2
- 238000012800 visualization Methods 0.000 description 2
- 241000282414 Homo sapiens Species 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K15/00—Devices for taming animals, e.g. nose-rings or hobbles; Devices for overturning animals in general; Training or exercising equipment; Covering boxes
- A01K15/02—Training or exercising equipment, e.g. mazes or labyrinths for animals ; Electric shock devices ; Toys specially adapted for animals
- A01K15/027—Exercising equipment, e.g. tread mills, carousels
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/01—Removal of dung or urine, e.g. from stables
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
- A01K1/03—Housing for domestic or laboratory animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
- A01K1/03—Housing for domestic or laboratory animals
- A01K1/031—Cages for laboratory animals; Cages for measuring metabolism of animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
- A01K1/035—Devices for use in keeping domestic animals, e.g. fittings in housings or dog beds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
- A01K1/035—Devices for use in keeping domestic animals, e.g. fittings in housings or dog beds
- A01K1/0356—Feeding or drinking devices associated with cages
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K15/00—Devices for taming animals, e.g. nose-rings or hobbles; Devices for overturning animals in general; Training or exercising equipment; Covering boxes
- A01K15/02—Training or exercising equipment, e.g. mazes or labyrinths for animals ; Electric shock devices ; Toys specially adapted for animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K29/00—Other apparatus for animal husbandry
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K29/00—Other apparatus for animal husbandry
- A01K29/005—Monitoring or measuring activity, e.g. detecting heat or mating
Abstract
The invention relates to an animal sleep deprivation device which comprises a box body, a cover plate module arranged at the upper end of the box body, a chassis module arranged at the lower end of the box body, a chassis driving device for driving the chassis module to rotate in a linkage way, and a fecal sample drying and collecting device arranged between the chassis module and the chassis driving device, wherein the chassis module comprises a rotating shaft connected with the chassis driving device and driven to rotate by the chassis driving device and a barrier rod detachably inserted into the rotating shaft, a plurality of hollow holes are formed in the rotating shaft at intervals, and the barrier rod is detachably inserted into any one of the hollow holes so as to adjust the height of the barrier rod according to the type and experimental requirements of experimental animals.
Description
Technical Field
The invention relates to the technical field of animal experiment devices, in particular to an animal sleep deprivation device which is used for experimental study of sleep deprivation modeling of rodents.
Background
Sleep is an extremely important physiological activity of animals and even human beings, and has the important functions of saving energy, promoting metabolism, enhancing immunity, promoting growth and development, enhancing learning and memory capacity, delaying aging and the like. Sleep disorders can directly affect brain activity and function and lead to disease and, in severe cases, life threatening.
Sleep deprivation experiments generally refer to scientific studies using mice or rats as target subjects and depriving their sleep behavior, and the establishment of a sleep deprivation model of mice and rats using an animal sleep deprivation device is a key element in basic research. The animal sleep deprivation model must be built to minimize stress other than the sleep deprivation stress itself, and to maximize the natural tendency to model the animal.
The patent publication number is CN208129162U, and Chinese patent application with publication day of 2018, 11 months and 23 days discloses a novel big mouse sleep deprivation instrument, which comprises a data acquisition box, a movable lifting platform, a thermal energy sensor, a motor-driven sleep deprivation rod, an independent test box and an animal drinking water feeding box, wherein the data acquisition box and the thermal energy sensor are arranged on a support at the top of the movable lifting platform, the independent test box is arranged on the plane at the bottom of the movable lifting platform, the motor-driven sleep deprivation rod is arranged at the bottom of the independent test box, and the animal drinking water feeding box is arranged on the side wall of the independent test box. However, the above-described existing animal sleep deprivation apparatus suffers from the following drawbacks: firstly, the design of a spiral scanning type sleep deprivation structure of an obstacle rod in the existing sleep deprivation instrument is basically that the height is fixed, the requirements of different experimental animals on the experimental height cannot be met, and the experiment has limitation; secondly, after the existing spiral scanning type sleep deprivation instrument using the barrier rod operates for a period of time in the sleep deprivation experiment of animals, if the instrument is not placed in a place with a good ventilation environment, water mist is easy to appear in the box body, the interference of factors such as humidity and the like of the animals in the box body is increased, and the effect of the sleep deprivation experiment is affected; thirdly, the existing spiral scanning type sleep deprivation instrument using the barrier rod is basically in a state close to a closed space, so that if the sleep deprivation duration of animals is longer, the excrement and urine at the bottom cannot be treated in time; fourth, the existing sleep deprivation instrument basically has no video recording function, and can not record and evaluate the behaviors and states of animals in experiments in real time.
Disclosure of Invention
Accordingly, an object of the present invention is to provide an animal sleep deprivation device with a height-adjustable barrier rod, no interference with the environment of sleep deprivation experiments, and a more natural sleep deprivation model during operation.
The utility model provides an animal sleep deprivation device, includes the box, set up in the apron module of the upper end of box, set up in the chassis module of box lower extreme, linkage drive chassis module pivoted chassis drive arrangement, and set up in chassis module with the dry collection device of excrement and urine sample between the chassis drive arrangement, wherein the chassis module including connect in chassis drive arrangement and by chassis drive arrangement drive pivoted pivot and detachably insert in the barrier pole of pivot, the interval is provided with a plurality of hollow holes in the pivot, barrier pole detachably insert and locate arbitrary one the hollow hole in order to adjust according to experimental animal type and experimental demand the height of barrier pole, the dry collection device of excrement and urine sample is used for collecting and drying experimental animal's excrement and urine.
In an embodiment of the present invention, a scale is further marked on the rotating shaft, a portion of the rotating shaft where the hollow hole is provided is located inside the box body, and a distance between adjacent hollow holes is set to be 1cm.
In an embodiment of the present invention, screw holes are formed on two sides of the hollow hole of the rotating shaft, and the barrier rod is fixedly connected with the rotating shaft through screws locked in the screw holes.
In an embodiment of the invention, the fecal sample drying and collecting device comprises a fence bottom plate arranged at the zero scale position of the rotating shaft and a fecal sample drying and collecting tray arranged between the fence bottom plate and the chassis driving device, wherein the fecal sample drying and collecting tray is provided with a concave groove for the fecal sample drying and collecting tray to be connected with the rotating shaft in a drawable manner, and the fecal sample drying and collecting tray is also provided with a urine pad.
In an embodiment of the invention, the cover plate module comprises a detachable cover plate, an ambient lighting lamp, a camera and a dehumidifier, wherein the ambient lighting lamp, the camera and the dehumidifier are all arranged on the detachable cover plate, the box is further provided with a hygrothermograph, the ambient lighting lamp is used for adjusting the brightness in the box, the camera is used for recording and observing the behaviors and states of experimental animals in real time, the hygrothermograph is used for monitoring the temperature and the humidity in the box in real time, and the dehumidifier is used for adjusting the humidity in the box based on the data monitored by the hygrothermograph.
In an embodiment of the invention, the camera is fixed by a cradle head and has a night vision function.
In an embodiment of the invention, the screen of the hygrothermograph faces outwards, and the switch buttons are arranged on two sides or the back of the screen.
In an embodiment of the invention, a round hole is formed in the detachable cover plate, and the round hole is an inlet for placing experimental animals.
In an embodiment of the invention, the box body is a transparent cylindrical box body, an animal feed feeding groove is arranged below the transparent cylindrical box body, an animal drinking bottle is fixedly arranged opposite to the animal feed feeding groove, and volume scales are marked on the bottle wall of the animal drinking bottle.
In an embodiment of the invention, the chassis driving device is a motor.
According to the animal sleep deprivation device, the plurality of hollow holes are formed in the rotating shaft at intervals, and the barrier rods are detachably inserted into any hollow holes, so that the height of the barrier rods can be selected according to animal types or experimental requirements, the experimental requirements of different animal types are met, and the possibility that feet are scraped due to the fact that the barrier rods are too low or the barrier rods are too high to cross the animal in the past due to the fact that the animal types are different is reduced.
According to the animal sleep deprivation device, the rotating shaft connected with the barrier rod is marked with the graduated scale, so that the accuracy of height adjustment can be ensured.
According to the animal sleep deprivation device, the hygrothermograph, the small dehumidifier and the environment lighting lamp capable of regulating the brightness are additionally arranged, so that the temperature and the humidity of the animal sleep deprivation environment can be monitored in real time, and when the humidity is too high, the small dehumidifier can be started. In addition, the brightness in the box body can be adjusted by starting and adjusting an ambient lighting lamp according to experimental requirements and ambient lighting conditions.
According to the animal sleep deprivation device, the barrier bottom plate is arranged at the bottom of the barrier rod, so that animal feces and urine can fall onto the tray below. Meanwhile, the urine pad is arranged on the tray, so that urine can be absorbed in time, and the excrement is ensured to be dried and collected.
According to the animal sleep deprivation device, the cradle head and the camera with the night vision function are additionally arranged, so that behavior data of animals in an experiment can be continuously recorded and observed.
Further objects and advantages of the present invention will become fully apparent from the following description and the accompanying drawings.
Drawings
Fig. 1 is a schematic view showing the overall structure of the animal sleep deprivation device according to a preferred embodiment of the present invention.
Fig. 2 is a schematic top view of a cover module of the animal sleep deprivation device according to the above preferred embodiment of the invention.
Fig. 3 is a schematic view showing the structure of a barrier floor of the animal sleep deprivation device according to the above preferred embodiment of the present invention.
Fig. 4 is a schematic view showing the structure of a stool sample drying and collecting tray of the animal sleep deprivation device according to the above preferred embodiment of the present invention.
Fig. 5 is a front view schematically showing a rotation shaft of the animal sleep deprivation device according to the above preferred embodiment of the present invention.
Fig. 6 is a schematic view showing the structure of the chassis module of the animal sleep deprivation device according to the above preferred embodiment of the present invention.
Reference numerals illustrate: a detachable cover plate 1; a case 2; chassis driving means 3; a fence base plate 4; a stool sample drying and collecting tray 5; an ambient lighting lamp 6; a camera 7; a dehumidifier 8; a hygrothermograph 9; an animal feed feeding trough 10; an animal drinking bottle 11; a rotating shaft 13; a barrier lever 14; a waterproof rubber ring 15; a hollow hole 16; screw holes 17; a scale 18.
Detailed Description
The following description is presented to enable one of ordinary skill in the art to make and use the invention. The preferred embodiments in the following description are by way of example only and other obvious variations will occur to those skilled in the art. The basic principles of the invention defined in the following description may be applied to other embodiments, variations, modifications, equivalents, and other technical solutions without departing from the spirit and scope of the invention.
It will be appreciated by those skilled in the art that in the present disclosure, the terms "vertical," "transverse," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," etc. refer to an orientation or positional relationship based on that shown in the drawings, which is merely for convenience of description and to simplify the description, and do not indicate or imply that the apparatus or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore the above terms should not be construed as limiting the present invention.
It will be understood that the terms "a" and "an" should be interpreted as referring to "at least one" or "one or more," i.e., in one embodiment, the number of elements may be one, while in another embodiment, the number of elements may be plural, and the term "a" should not be interpreted as limiting the number.
In the description of the present invention, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically connected, electrically connected or can be communicated with each other; can be directly connected or indirectly connected through an intermediate medium, and can be communicated with the inside of two elements or the interaction relationship of the two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art according to the specific circumstances.
The invention provides an animal sleep deprivation device, in particular to an experimental study for sleep deprivation modeling of rodents. The invention comprises the following devices: the device comprises a barrier rod spiral scanning type sleep deprivation device, a behavioural recording device, a temperature and humidity detection and adjustment device, an ambient lighting lamp with adjustable brightness, a barrier structure below the barrier rod and a dry excrement sample collection device consisting of a tray with a urine pad. The output end of the rotating machine of the sleep deprivation chassis is connected with the barrier rod, and meanwhile, the output end of the chassis is connected with the small dehumidifier, the environment lighting lamp and the behavioural camera, so that the influence of other factors on the sleep deprivation modeling of animals is reduced as much as possible, the barrier rod with adjustable period is utilized to spiral and scan the bottom of the raising cage, the barrier-free sleep deprivation experimental environment of animals is realized, and the sleep deprivation modeling of the device in the operation process is more close to a natural state.
In particular, as shown in fig. 1 to 6, a specific structure of an animal sleep deprivation device according to a preferred embodiment of the present invention is elucidated.
As shown in fig. 1, the animal sleep deprivation device comprises a box body 2, a cover plate module arranged at the upper end of the box body 2, a chassis module arranged at the lower end of the box body 2, a chassis driving device 3 for driving the chassis module to rotate in a linkage manner, and a fecal sample drying and collecting device arranged between the chassis module and the chassis driving device 3, wherein the chassis module comprises a rotating shaft 13 connected with the chassis driving device 3 and driven to rotate by the chassis driving device 3 and a barrier rod 14 detachably inserted into the rotating shaft 13, a plurality of hollow holes 16 are formed in the rotating shaft 13 at intervals, and the barrier rod 14 is detachably inserted into any one of the hollow holes 16 so as to facilitate the adjustment of the height of the barrier rod 14 according to the type and experimental requirements of experimental animals, and the fecal sample drying and collecting device is used for collecting and drying the fecal of the experimental animals.
It will be appreciated that the animal sleep deprivation device adopts the mode of detachably inserting the barrier rod 14 into any hollow hole 16 by arranging a plurality of hollow holes 16 on the rotating shaft 13 at intervals, so that the height of the barrier rod 14 can be selected according to animal types or experimental requirements, the experimental requirements of different animal types are met, and the possibility that the animal cannot cross the past because the barrier rod is too low to scratch feet or too high because of different animals is reduced.
Further, as shown in fig. 1 and 2, the cover plate module comprises a detachable cover plate 1, an ambient lighting lamp 6, a camera 7 and a dehumidifier 8, wherein the ambient lighting lamp 6, the camera 7 and the dehumidifier 8 are all arranged on the detachable cover plate 1, the box body 2 is further provided with a hygrothermograph 9, the ambient lighting lamp 6 is used for adjusting the brightness in the box body 2, the camera 7 is used for recording and observing the behaviors and states of experimental animals in real time, the hygrothermograph is used for monitoring the temperature and the humidity in the box body 2 in real time, and the dehumidifier 8 is used for adjusting the humidity in the box body 2 based on the data monitored by the hygrothermograph.
It should be noted that the screen of the hygrothermograph 9 faces outwards, and the switch buttons are arranged on two sides or the back of the screen.
In addition, it should be noted that a round hole is provided on the detachable cover plate 1, and the round hole is an inlet for placing experimental animals.
Particularly, the camera 7 is fixed by a holder and has a night vision function, and the animal sleep deprivation device can continuously record and observe the behavior and state of an animal in an experiment by adding the holder and the camera 7 with the night vision function.
It can be understood that, in order to avoid water mist caused by too high humidity in the box 2, that is, in order to avoid interference of factors such as increasing humidity of animals in the box 2, the animal sleep deprivation device of the invention is additionally provided with the hygrothermograph 9, the small-sized dehumidifier 8 and the ambient lighting lamp 6 capable of adjusting brightness, so that the temperature and humidity of the animal sleep deprivation environment can be monitored in real time, and when the humidity is too high, the small-sized dehumidifier 8 can be started to dehumidify. In addition, the brightness in the box body 2 can be selected by starting and adjusting the ambient lighting lamp 6 according to the experimental requirements and the ambient lighting conditions.
It should be noted that the case 2 is a transparent cylindrical case with both hollow ends, so as to facilitate real-time observation of the situation in the case 2. An animal feed feeding trough 10 is arranged below the transparent cylindrical box body, an animal drink bottle 11 is fixedly arranged on the opposite side of the animal feed feeding trough 10, volume scales are marked on the bottle wall of the animal drink bottle 11 and are used for displaying the volume of residual water in the animal drink bottle 11.
Further, as shown in fig. 3 and 4, the fecal sample drying and collecting device comprises a fence base plate 4 arranged at the zero scale position of the rotating shaft 13 and a fecal sample drying and collecting tray 5 arranged between the fence base plate 4 and the chassis driving device 3, wherein the fecal sample drying and collecting tray 5 is provided with a concave groove so that the fecal sample drying and collecting tray 5 can be connected with the rotating shaft 13 in a drawable manner, and the fecal sample drying and collecting tray 5 is also provided with a urine pad.
It should be noted that a waterproof rubber ring 15 is disposed at the upper end of the connection portion between the rotating shaft 13 and the fence bottom plate 4.
It will be appreciated that the barrier floor 4 is provided at the bottom of the barrier bar 14 so that animal faeces and urine may fall onto the faecal sample drying and collecting tray 5 below. Meanwhile, the urine pad is arranged on the excrement sample drying and collecting tray 5, urine can be absorbed in time, and the drying and collecting of excrement are guaranteed, so that the sanitation level in the box body 2 can be guaranteed to the greatest extent.
In particular, as shown in fig. 5 and 6, a scale 18 is further marked on the rotating shaft 13, a portion of the rotating shaft 13 where the hollow holes 16 are provided is located inside the case 2, a distance between adjacent hollow holes 16 is set to 1cm, and a distance between a center of a lowest hollow hole 16 and the fence bottom plate 4 is also set to 1cm.
It should be noted that in this embodiment, the total of 3 heights, 1cm, 2cm, and 3cm, are disposed on the rotating shaft 13, and in other embodiments of the present invention, more heights may be selected according to different experimental animal types and experimental requirements, and other distances between adjacent hollow holes 16 may be set to be equal or different, and may be flexibly set according to actual experimental requirements, which is not limited in the present invention.
Further, as shown in fig. 6, screw holes 17 are formed on both sides of the hollow hole 16 of the rotating shaft 13, and the barrier rod 14 is fixedly connected with the rotating shaft 13 by a screw locked in the screw holes 17.
It should be understood that the chassis module forms the barrier rod spiral scanning type sleep deprivation device of the invention, the camera 7 forms the behavioural recording device of the invention, the hygrothermograph 9 and the dehumidifier 8 form the humiture detection and humidity adjustment device of the invention, the fence base plate 4 and the excrement sample drying and collecting tray 5 with urine pad form the dry excrement sample collecting device of the invention, the chassis driving device 3 can adopt a motor as a rotating machine, the output end of the rotating machine is connected with the rotating shaft 13 and is connected with the barrier rod 14 through the rotating shaft 13, and the output end of the chassis driving device 3 is connected with the dehumidifier 8, the ambient lighting lamp 6 and the camera 7 to provide an unobstructed sleep deprivation experiment environment for the box body 2.
It will also be appreciated that the animal sleep deprivation device of the present invention provides for the selection of the height of three barrier rods and the visualization of the height of the barrier rods 14 as compared to existing mouse sleep deprivation devices; the animal sleep deprivation device is further provided with the hygrothermograph 9, the ambient lighting lamp 6 with adjustable brightness and the dehumidifier 8, so that the temperature and humidity in the box body 2 can be monitored in real time, the light intensity and the humidity can be adjusted according to specific experimental requirements, and the environment is ensured to be more similar to a natural state in the running process of the device; in addition, the animal sleep deprivation device is provided with the tray with the urine pad at the lowest part, so that a relatively dry animal feces sample can be collected, and meanwhile, the influence of animal feces accumulation on an experimental environment caused by long-time operation can be avoided. Finally, the animal sleep deprivation device is additionally provided with a camera 7 with a night vision function, is used for behavioural recording in the animal sleep deprivation experiment process, and can record the behaviors and states of experimental animals in the box body 2 in real time.
In general, the invention provides the animal sleep deprivation device which has the advantages of adjustable height of the barrier rod, high visualization, adjustable brightness and temperature and humidity, can keep the sanitation and the cleanness in the box body, and can record the behaviors and the states of experimental animals in real time, and is particularly suitable for experimental study of sleep deprivation modeling of rodents.
The technical features of the above embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.
The foregoing examples only represent preferred embodiments of the present invention, which are described in more detail and are not to be construed as limiting the scope of the invention. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the invention, which are all within the scope of the invention. Accordingly, the scope of protection of the present invention is to be determined by the appended claims.
Claims (10)
1. The utility model provides an animal sleep deprivation device, its characterized in that, including the box, set up in the apron module of the upper end of box, set up in chassis module, the linkage drive of box lower extreme chassis module pivoted chassis drive arrangement, and set up in chassis module with the dry collection device of excrement and urine sample between the chassis drive arrangement, wherein the chassis module including connect in chassis drive arrangement and by chassis drive arrangement drive pivoted pivot and detachably insert locate the barrier pole of pivot, the interval is provided with a plurality of hollow holes in the pivot, barrier pole detachably insert and locate arbitrary one the hollow hole is so that according to experimental animal type and experimental demand regulation the height of barrier pole, the dry collection device of excrement and urine sample is used for collecting and drying experimental animal's excrement and urine.
2. The animal sleep deprivation device according to claim 1, wherein a scale is further marked on the rotation shaft, a portion of the rotation shaft where the hollow holes are provided is located inside the case, and a distance between adjacent hollow holes is set to 1cm.
3. The sleep deprivation device according to claim 2, wherein screw holes are provided at both sides of the hollow hole of the rotation shaft, and the barrier rod is fixedly connected to the rotation shaft by a screw locked to the screw holes.
4. The animal sleep deprivation device according to claim 3 wherein said fecal sample drying and collecting device comprises a fence base plate disposed at a zero scale position of said spindle and a fecal sample drying and collecting tray disposed between said fence base plate and said chassis drive, said fecal sample drying and collecting tray being provided with a concave groove for said fecal sample drying and collecting tray to be drawably connected to said spindle, said fecal sample drying and collecting tray being further provided with a urine pad.
5. The animal sleep deprivation device according to any one of claims 1-4 wherein the cover module comprises a detachable cover and an ambient lighting lamp, a camera and a dehumidifier both disposed on the detachable cover, the box further being provided with a hygrothermograph, the ambient lighting lamp being used for adjusting the brightness in the box, the camera being used for recording and observing the behavior and status of the experimental animal in real time, the hygrothermograph being used for monitoring the temperature and humidity in the box in real time, the dehumidifier being used for adjusting the humidity in the box based on the data monitored by the hygrothermograph.
6. The animal sleep deprivation device according to claim 5 wherein the camera is fixed with a cradle head and has night vision.
7. The animal sleep deprivation device according to claim 5 wherein the thermometer screen is outwardly facing and the switch buttons are provided on either side or the back of the thermometer screen.
8. The animal sleep deprivation device according to claim 5 wherein the removable cover plate is provided with a circular aperture, the circular aperture being an inlet for placement of an experimental animal.
9. The sleep deprivation device according to claim 5 wherein the housing is a transparent cylindrical housing, an animal feed feeding trough is provided below the transparent cylindrical housing, and an animal water bottle is fixedly provided opposite the animal feed feeding trough, and a volume scale is marked on a wall of the animal water bottle.
10. The animal sleep deprivation device according to any one of claims 1-4 wherein the chassis drive is a motor.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210152428.2A CN116649239A (en) | 2022-02-18 | 2022-02-18 | animal sleep deprivation device |
| PCT/CN2022/137080 WO2023155551A1 (en) | 2022-02-18 | 2022-12-06 | Animal sleep deprivation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210152428.2A CN116649239A (en) | 2022-02-18 | 2022-02-18 | animal sleep deprivation device |
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| Publication Number | Publication Date |
|---|---|
| CN116649239A true CN116649239A (en) | 2023-08-29 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210152428.2A Pending CN116649239A (en) | 2022-02-18 | 2022-02-18 | animal sleep deprivation device |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN116649239A (en) |
| WO (1) | WO2023155551A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117065176B (en) * | 2023-10-15 | 2023-12-19 | 北京脑科学与类脑研究所 | Rodent sleep deprivation device and deprivation system based on machine vision |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090203958A1 (en) * | 2008-02-07 | 2009-08-13 | David Alan Johnson | Apparatus and method for automatically inducing sleep deprivation in rodents |
| CN209120922U (en) * | 2018-11-01 | 2019-07-19 | 中国人民解放军陆军军医大学 | Experimental animal sleep deprivation device |
| CN113546272A (en) * | 2020-04-02 | 2021-10-26 | 中国科学院上海有机化学研究所 | Experimental animals sleep disturbing device |
| CN111742847A (en) * | 2020-07-15 | 2020-10-09 | 华中科技大学同济医学院附属同济医院 | Built-in animal sleep deprivation device |
| CN213343917U (en) * | 2020-09-25 | 2021-06-04 | 军事科学院军事医学研究院环境医学与作业医学研究所 | Sleep deprivation device suitable for rodent |
| CN114145235A (en) * | 2021-12-09 | 2022-03-08 | 中国科学院深圳先进技术研究院 | Sleep deprivation device capable of collecting excrement of small animals |
-
2022
- 2022-02-18 CN CN202210152428.2A patent/CN116649239A/en active Pending
- 2022-12-06 WO PCT/CN2022/137080 patent/WO2023155551A1/en unknown
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| WO2023155551A1 (en) | 2023-08-24 |
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