CN111467279A - Multi-effect whitening and freckle-removing essence cream and preparation method thereof - Google Patents
Multi-effect whitening and freckle-removing essence cream and preparation method thereof Download PDFInfo
- Publication number
- CN111467279A CN111467279A CN202010455781.9A CN202010455781A CN111467279A CN 111467279 A CN111467279 A CN 111467279A CN 202010455781 A CN202010455781 A CN 202010455781A CN 111467279 A CN111467279 A CN 111467279A
- Authority
- CN
- China
- Prior art keywords
- parts
- whitening
- agent
- prepared
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000002087 whitening effect Effects 0.000 title claims abstract description 117
- 239000006071 cream Substances 0.000 title claims abstract description 44
- 208000003351 Melanosis Diseases 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title claims abstract description 24
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 90
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 claims abstract description 16
- 108010024636 Glutathione Proteins 0.000 claims abstract description 8
- 229960003180 glutathione Drugs 0.000 claims abstract description 8
- 229940065115 grapefruit extract Drugs 0.000 claims abstract description 8
- QAQJMLQRFWZOBN-LAUBAEHRSA-N L-ascorbyl-6-palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O QAQJMLQRFWZOBN-LAUBAEHRSA-N 0.000 claims abstract description 7
- 239000011786 L-ascorbyl-6-palmitate Substances 0.000 claims abstract description 7
- 235000010385 ascorbyl palmitate Nutrition 0.000 claims abstract description 7
- 238000006243 chemical reaction Methods 0.000 claims description 45
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 37
- -1 dimethyl siloxane Chemical class 0.000 claims description 34
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims description 30
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 30
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 30
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 25
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 25
- 239000002904 solvent Substances 0.000 claims description 25
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims description 20
- 239000003963 antioxidant agent Substances 0.000 claims description 20
- 230000003078 antioxidant effect Effects 0.000 claims description 20
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 20
- 229920001577 copolymer Polymers 0.000 claims description 20
- 239000003995 emulsifying agent Substances 0.000 claims description 20
- 239000000839 emulsion Substances 0.000 claims description 20
- 239000004094 surface-active agent Substances 0.000 claims description 20
- 239000002562 thickening agent Substances 0.000 claims description 20
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 15
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 15
- 238000003756 stirring Methods 0.000 claims description 15
- 238000005303 weighing Methods 0.000 claims description 15
- 229940015975 1,2-hexanediol Drugs 0.000 claims description 10
- BANXPJUEBPWEOT-UHFFFAOYSA-N 2-methyl-Pentadecane Chemical compound CCCCCCCCCCCCCC(C)C BANXPJUEBPWEOT-UHFFFAOYSA-N 0.000 claims description 10
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims description 10
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 10
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 10
- 229960000458 allantoin Drugs 0.000 claims description 10
- 229920006037 cross link polymer Polymers 0.000 claims description 10
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 10
- 238000004945 emulsification Methods 0.000 claims description 10
- 238000011049 filling Methods 0.000 claims description 10
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 10
- 239000011159 matrix material Substances 0.000 claims description 10
- 238000004806 packaging method and process Methods 0.000 claims description 10
- 229940078492 ppg-17 Drugs 0.000 claims description 10
- 235000010384 tocopherol Nutrition 0.000 claims description 10
- 229960001295 tocopherol Drugs 0.000 claims description 10
- 229930003799 tocopherol Natural products 0.000 claims description 10
- 239000011732 tocopherol Substances 0.000 claims description 10
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 10
- 239000000230 xanthan gum Substances 0.000 claims description 9
- 229920001285 xanthan gum Polymers 0.000 claims description 9
- 229940082509 xanthan gum Drugs 0.000 claims description 9
- 235000010493 xanthan gum Nutrition 0.000 claims description 9
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 8
- 230000003020 moisturizing effect Effects 0.000 claims description 8
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 8
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 8
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 claims description 7
- 229940086555 cyclomethicone Drugs 0.000 claims description 7
- PQUXFUBNSYCQAL-UHFFFAOYSA-N 1-(2,3-difluorophenyl)ethanone Chemical compound CC(=O)C1=CC=CC(F)=C1F PQUXFUBNSYCQAL-UHFFFAOYSA-N 0.000 claims description 5
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 5
- 229940043268 2,2,4,4,6,8,8-heptamethylnonane Drugs 0.000 claims description 5
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 5
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 5
- OMIGHNLMNHATMP-UHFFFAOYSA-N 2-hydroxyethyl prop-2-enoate Chemical compound OCCOC(=O)C=C OMIGHNLMNHATMP-UHFFFAOYSA-N 0.000 claims description 5
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 5
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 5
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 claims description 5
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims description 5
- IUMSDRXLFWAGNT-UHFFFAOYSA-N Dodecamethylcyclohexasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 IUMSDRXLFWAGNT-UHFFFAOYSA-N 0.000 claims description 5
- 241000186660 Lactobacillus Species 0.000 claims description 5
- 239000004698 Polyethylene Substances 0.000 claims description 5
- NWGKJDSIEKMTRX-AAZCQSIUSA-N Sorbitan monooleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O NWGKJDSIEKMTRX-AAZCQSIUSA-N 0.000 claims description 5
- FGUZFFWTBWJBIL-XWVZOOPGSA-N [(1r)-1-[(2s,3r,4s)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)O[C@H](CO)[C@H]1OC[C@H](O)[C@H]1O FGUZFFWTBWJBIL-XWVZOOPGSA-N 0.000 claims description 5
- 229940048053 acrylate Drugs 0.000 claims description 5
- 239000012752 auxiliary agent Substances 0.000 claims description 5
- KIUVQMGRTDPAFR-UHFFFAOYSA-N benzoic acid 2-hydroxy-2-phenylpropanamide Chemical compound C(C1=CC=CC=C1)(=O)O.OC(C(=O)N)(C)C1=CC=CC=C1 KIUVQMGRTDPAFR-UHFFFAOYSA-N 0.000 claims description 5
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 claims description 5
- 238000007599 discharging Methods 0.000 claims description 5
- 230000001804 emulsifying effect Effects 0.000 claims description 5
- 150000002148 esters Chemical class 0.000 claims description 5
- 238000001704 evaporation Methods 0.000 claims description 5
- 230000008020 evaporation Effects 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- FOYKKGHVWRFIBD-UHFFFAOYSA-N gamma-tocopherol acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 FOYKKGHVWRFIBD-UHFFFAOYSA-N 0.000 claims description 5
- 238000009499 grossing Methods 0.000 claims description 5
- 239000012535 impurity Substances 0.000 claims description 5
- KUVMKLCGXIYSNH-UHFFFAOYSA-N isopentadecane Natural products CCCCCCCCCCCCC(C)C KUVMKLCGXIYSNH-UHFFFAOYSA-N 0.000 claims description 5
- 229940039696 lactobacillus Drugs 0.000 claims description 5
- 239000000787 lecithin Substances 0.000 claims description 5
- 229940067606 lecithin Drugs 0.000 claims description 5
- 235000010445 lecithin Nutrition 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims description 5
- 229960005323 phenoxyethanol Drugs 0.000 claims description 5
- 229920000573 polyethylene Polymers 0.000 claims description 5
- 229940093932 potassium hydroxide Drugs 0.000 claims description 5
- 239000000377 silicon dioxide Substances 0.000 claims description 5
- 239000002893 slag Substances 0.000 claims description 5
- 229940047670 sodium acrylate Drugs 0.000 claims description 5
- 229940057429 sorbitan isostearate Drugs 0.000 claims description 5
- 229950004959 sorbitan oleate Drugs 0.000 claims description 5
- 239000004408 titanium dioxide Substances 0.000 claims description 5
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims description 5
- 229920002554 vinyl polymer Polymers 0.000 claims description 5
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 2
- 229920002674 hyaluronan Polymers 0.000 claims description 2
- 229960003160 hyaluronic acid Drugs 0.000 claims description 2
- 239000000314 lubricant Substances 0.000 claims description 2
- 239000011782 vitamin Substances 0.000 claims 1
- 229940088594 vitamin Drugs 0.000 claims 1
- 229930003231 vitamin Natural products 0.000 claims 1
- 235000013343 vitamin Nutrition 0.000 claims 1
- 150000003722 vitamin derivatives Chemical class 0.000 claims 1
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 abstract description 22
- 230000000694 effects Effects 0.000 abstract description 11
- 241000282414 Homo sapiens Species 0.000 abstract description 8
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 abstract description 5
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 abstract description 4
- BJRNKVDFDLYUGJ-ZIQFBCGOSA-N alpha-Arbutin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC1=CC=C(O)C=C1 BJRNKVDFDLYUGJ-ZIQFBCGOSA-N 0.000 abstract description 4
- 229940033280 alpha-arbutin Drugs 0.000 abstract description 4
- GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 abstract description 4
- 229960000401 tranexamic acid Drugs 0.000 abstract description 4
- 208000012641 Pigmentation disease Diseases 0.000 abstract description 3
- 230000015572 biosynthetic process Effects 0.000 abstract description 3
- 208000020154 Acnes Diseases 0.000 abstract description 2
- 229940124158 Protease/peptidase inhibitor Drugs 0.000 abstract description 2
- 102000003425 Tyrosinase Human genes 0.000 abstract description 2
- 108060008724 Tyrosinase Proteins 0.000 abstract description 2
- 229960003966 nicotinamide Drugs 0.000 abstract description 2
- 235000005152 nicotinamide Nutrition 0.000 abstract description 2
- 239000011570 nicotinamide Substances 0.000 abstract description 2
- 239000000137 peptide hydrolase inhibitor Substances 0.000 abstract description 2
- 239000011148 porous material Substances 0.000 abstract description 2
- 230000005855 radiation Effects 0.000 abstract description 2
- 206010014970 Ephelides Diseases 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 47
- 239000000686 essence Substances 0.000 description 41
- 239000000047 product Substances 0.000 description 26
- 235000006708 antioxidants Nutrition 0.000 description 16
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 10
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 6
- BJRNKVDFDLYUGJ-RMPHRYRLSA-N hydroquinone O-beta-D-glucopyranoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=C(O)C=C1 BJRNKVDFDLYUGJ-RMPHRYRLSA-N 0.000 description 6
- 230000007935 neutral effect Effects 0.000 description 6
- 239000000843 powder Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 5
- 230000003712 anti-aging effect Effects 0.000 description 4
- 235000010323 ascorbic acid Nutrition 0.000 description 4
- 239000011668 ascorbic acid Substances 0.000 description 4
- 229960005070 ascorbic acid Drugs 0.000 description 4
- 229920001296 polysiloxane Polymers 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 229960000271 arbutin Drugs 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 239000010410 layer Substances 0.000 description 3
- BJRNKVDFDLYUGJ-UHFFFAOYSA-N p-hydroxyphenyl beta-D-alloside Natural products OC1C(O)C(O)C(CO)OC1OC1=CC=C(O)C=C1 BJRNKVDFDLYUGJ-UHFFFAOYSA-N 0.000 description 3
- 241001237961 Amanita rubescens Species 0.000 description 2
- 206010013786 Dry skin Diseases 0.000 description 2
- 108091005804 Peptidases Proteins 0.000 description 2
- 239000004365 Protease Substances 0.000 description 2
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 238000005034 decoration Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 210000002615 epidermis Anatomy 0.000 description 2
- 239000002932 luster Substances 0.000 description 2
- 230000019612 pigmentation Effects 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 229920005573 silicon-containing polymer Polymers 0.000 description 2
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010039792 Seborrhoea Diseases 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000003915 cell function Effects 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000010339 dilation Effects 0.000 description 1
- 230000037336 dry skin Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000009707 neogenesis Effects 0.000 description 1
- 230000037312 oily skin Effects 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 229950008882 polysorbate Drugs 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000005808 skin problem Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/29—Titanium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
- A61K8/585—Organosilicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A61K2800/72—Hypo-allergenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Emergency Medicine (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a multi-effect whitening and freckle-removing essence cream and a preparation method thereof, and relates to the technical field of skin care products, wherein nicotinamide, a whitening agent I, a whitening agent II, α -arbutin and tranexamic acid are added into the components of the existing essence cream, wherein the nicotinamide can play a role in whitening, controlling oil, shrinking pores and removing acnes on skin, α -arbutin can inhibit the activity of tyrosinase, so that melanin formation is inhibited, the tranexamic acid is a protease inhibitor, so that black speckles can not be thickened, enlarged and increased, so that skin pigmentation can be effectively prevented and improved, the whitening agent I contains a grape fruit extract and glutathione, the grape fruit extract can effectively prevent and reduce the damage of ultraviolet radiation to the skin, the glutathione can remove freckles and whiten, the whitening agent II contains ascorbyl palmitate, and the ascorbyl palmitate plays a role in resisting oxidation and whitening of human skin.
Description
Technical Field
The invention relates to the technical field of skin care products, and particularly relates to a multi-effect whitening and freckle removing essence cream and a preparation method thereof.
Background
The essence cream is the most important step of basic skin care, and effective components in the essence cream, such as whitening, anti-aging and the like, can be better absorbed by skin; the water content is high; easy to push evenly and quickly permeate into the skin epidermis, and easy to be absorbed and has high water retention. The components for moistening the skin can be easily retained and are not easily evaporated, and a certain moisture content of the skin is maintained; is not greasy; the oil content is low, and the oil control effect is better. The essence cream has double anti-aging effects, can stimulate cell neogenesis energy, promote collagen synthesis, improve the texture and the skin color uniformity of the skin surface layer, and make the skin more delicate.
With the development of society and the improvement of living standard of people, the requirements of consumers on daily care products are higher and higher, and the requirements on the efficacy of the product are more and more refined. Because of the skin color problem of yellow people, Asian women generally have the problems of dark skin color, dark yellow color, lack of luster, easy allergy, pigmentation and the like. Due to the traditional beauty concept of 'one white covering three ugs', the pursuit of whitening by Asian women never stops just like the pursuit of brightness by human beings, blusher powder is almost the must of every adult woman, and by now, the blusher powder is a general powder decoration family of forests such as concealer, foundation make-up, loose powder, powder cake and the like, and the powder decoration is too white and smooth. In fact, whitening is just like treating diseases, the symptoms are not as permanent as treating the diseases, and only by well conditioning the internal skin and radically treating melanin which is the main factor affecting whitening, the skin can show real natural whitening luster from inside to outside.
Melanin is a protein existing in the basal layer of skin of each person, and the melanin is changed by ultraviolet irradiation to generate a substance for protecting the skin, and then the melanin moves to the skin epidermal layer through cell metabolism layer by layer, so that the skin problems of color spots, uneven skin color and the like seen by people at present are formed.
In summary, the technical personnel in the field provide the multi-effect whitening and freckle-removing essence cream and the preparation method thereof.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides a multi-effect whitening and freckle-removing essence cream and a preparation method thereof, and solves the problem that the skin of a human body has defects due to the existence of melanin in the background technology.
The multiple-effect whitening and freckle-removing essence cream comprises the following components, by weight, 20.0-25.0 parts of water, 0.3-0.8 part of butanediol, 0.4-0.7 part of cyclomethicone, 1.2-1.6 parts of propylene glycol, 1.7-2.1 parts of PEG/PPG-17/6 copolymer, 2.5-3.0 parts of a skin slipping agent, 0.8-1.1 parts of 1, 2-hexanediol, 0.8-1.1 parts of p-hydroxyacetophenone, 1.3-1.6 parts of an emulsifier, 1.8-2.0 parts of a thickener, 0.9-1.5 parts of a surfactant, 2.3-2.7 parts of a moisturizing agent, 0.5-0.9 part of tocopherol acetic acid, 1.2-1.7 parts of an antioxidant, 0.1-0.3 part of allantoin, 1.2-1.5 parts of potassium hydroxide, 1.3-2.7 parts of a hyaluronic acid, 0.5-1.6 parts of a whitening and freckle-removing essence, and further comprises the following components, namely, 1.2-1.2.5 parts of a whitening and 358 parts of an anti-2.6 parts of an anti-2.8 parts of a whitening essence;
the whitening agent I is prepared from the following components in parts by weight: 1.7-2.4 parts of grape fruit extract, 0.7-1.3 parts of butanediol, 1.3-2.0 parts of glutathione and 1.7-2.4 parts of lactobacillus;
the whitening agent II is prepared from the following components in parts by weight: 0.6-1.1 parts of 1, 2-pentanediol, 0.3-0.8 part of butanediol, 0.7-1.2 parts of hydroxyphenylpropionamide benzoic acid and 1.4-2.3 parts of ascorbyl palmitate.
Preferably, the skin smoothing agent is prepared from the following components in parts by weight: 0.5-1.2 parts of cyclopenta dimethyl siloxane, 0.2-0.5 part of cyclotetra dimethyl siloxane and 0.5-1.2 parts of dimethiconol.
Preferably, the emulsifier is prepared from the following components in parts by weight: 18-23 parts of water, 2.5-3.0 parts of lecithin, 1.7-2.7 parts of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.6-1.3 parts of cyclopenta polydimethylsiloxane, 1.4-1.8 parts of cyclohexasiloxane, 0.3-0.7 part of polydimethylsiloxane, 2.4-2.9 parts of glycerol, 1.3-1.7 parts of phenoxyethanol and 0.2-0.7 part of p-hydroxyacetophenone.
Preferably, the thickener is prepared from the following components in parts by weight: 3.6-4.4 parts of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer and 1.8-2.5 parts of cyclohexane.
Preferably, the surfactant is prepared from the following components in parts by weight: 3.1-4.3 parts of hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, 2.6-2.78 parts of polysorbate-601.7, 0.9-1.4 parts of sorbitan isostearate and 15-21 parts of water.
Preferably, the water replenishing agent is prepared from the following components in parts by weight: 4.1-6.3 parts of sodium acrylate/sodium acryloyldimethyl taurate copolymer, 2.4-3.1 parts of isohexadecane, 0.9-0.78 part of polysorbate-800.4, 26-30 parts of water and 1.5-2.4 parts of sorbitan oleate.
Preferably, the antioxidant is prepared from the following components in parts by weight: 0.7-1.3 parts of PEG-12 polydimethylsiloxane, 122.3-2.8 parts of polyethylene glycol-3 and 3.4-5.2 parts of tocopherol.
Preferably, the anti-ultraviolet agent is prepared from the following components in parts by weight: 3.9-5.8 parts of titanium dioxide and 4.7-7.1 parts of silica.
The preparation method of the multi-effect whitening and freckle-removing essence cream comprises the following steps:
s1, preparation aid: respectively weighing the components of the skin slipping agent, the emulsifier, the thickening agent, the surfactant, the moisturizing agent, the antioxidant and the anti-ultraviolet agent according to the proportion, sequentially preparing the finished product of the auxiliary agent by using a reaction kettle, and respectively storing the finished product in different storage tanks for later use;
s2, preparing the whitening agent: respectively weighing the components in the whitening agent I and the whitening agent II according to the proportion, and respectively and correspondingly preparing the whitening agent I and the whitening agent II by utilizing a reaction kettle A and a reaction kettle B, wherein the stirring rotating speed of the reaction kettle A is controlled to be 450-ion 600r/min, the internal temperature is controlled to be 35-50 ℃, the internal pressure is controlled to be 0.8-1.1MPa, the stirring rotating speed of the reaction kettle B is controlled to be 550-ion 750r/min, the internal temperature is controlled to be 45-60 ℃, and the internal pressure is controlled to be 0.9-1.2MPa, so as to obtain the finished products of the whitening agent I and the whitening agent II, then respectively storing the finished products in two storage tanks, and reserving the finished products for later use;
s3, preparation solvent: respectively weighing water, butanediol, cyclomethicone, propylene glycol, PEG/PPG-17/6 copolymer, 1, 2-hexanediol, p-hydroxyacetophenone, tocopheryl acetate, allantoin, potassium hydroxide, sodium hyaluronate, xanthan gum and essence according to the proportion, sequentially adding the weighed components into a reaction kettle according to the sequence of the components, adjusting the rotating speed of the reaction kettle to be 650-700r/min, controlling the internal temperature to be 60-75 ℃, controlling the internal pressure to be 1.1-1.3MPa, uniformly stirring to obtain a matrix solvent, sequentially adding the water replenishing agent, the antioxidant, the anti-ultraviolet agent, the skin lubricant and the surfactant prepared in the step S1 into the reaction kettle containing the matrix solvent, adjusting the rotating speed of the reaction kettle to be 800-950r/min, controlling the internal temperature to be 40-50 ℃, controlling the internal pressure to be 0.7-1.2MPa, obtaining a solvent, and discharging for later use;
s4, emulsification and mixing: sequentially adding the solvent obtained in the step S3 and the whitening agent I and the whitening agent II obtained in the step S2 to an emulsifying machine, and then adding the emulsifier and the thickener prepared in the step S1 until complete emulsification and discharge to obtain a mixed emulsion;
s5, deslagging: transferring the mixed emulsion obtained in the step S4 to a filtering device to remove impurities contained in the mixed emulsion;
s6, concentration: adding the mixed emulsion subjected to slag removal in the step S5 into evaporation and concentration equipment to obtain finished product essence cream;
s7, packaging and warehousing: and (5) adding the finished product essence cream obtained in the step S6 into a filling machine, subpackaging into packaging bottles by the filling machine, and storing in storage.
Advantageous effects
The invention provides a multi-effect whitening and freckle-removing essence cream and a preparation method thereof. Compared with the prior art, the method has the following beneficial effects:
the multi-effect whitening and freckle-removing essence cream and the preparation method thereof are characterized in that components with whitening and freckle removing functions are added into the components of the existing essence cream, wherein the whitening and freckle-removing components comprise nicotinamide, a whitening agent I, a whitening agent II, α -arbutin and tranexamic acid, the nicotinamide can whiten, control oil, shrink pores and remove acnes on skin, and can play a role in isolating and locking water and assisting in solving skin roughness so as to achieve the effects of skin tendering and blood vessel dilation, the α -arbutin can inhibit the activity of tyrosinase so as to inhibit the formation of melanin, the tranexamic acid is a protease inhibitor and can inhibit the catalytic action of protease on the hydrolysis of peptide bonds, so that the activity of enzymes such as hair-origin protease is prevented, the disorder of epidermal cell functions of the freckle part is inhibited, the melanin enhancement factor group is inhibited, the generation path of melanin formed due to ultraviolet irradiation is completely stopped, the freckle is not thickened, the melanin is enlarged and increased, the pigmentation of the skin can be effectively prevented and improved, the grape fruit extract and the glutathione are a vitamin C capable of effectively preventing, delaying the skin from being damaged by ultraviolet radiation, and capable of not only playing the effects of whitening, whitening and anti-aging of skin, but also can be a safe whitening, and anti-aging of skin.
Drawings
FIG. 1 is a block diagram of a preparation process of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The invention provides a technical scheme that the multi-effect whitening and freckle-removing essence cream comprises a basic component, wherein the basic component is prepared from the following components, by weight, 20.0 parts of water, 0.3 part of butanediol, 0.4 part of cyclopolydimethylsiloxane, 1.2 parts of propylene glycol, 1.7 parts of PEG/PPG-17/6 copolymer, 2.5 parts of a skin slipping agent, 0.8 part of 1, 2-hexanediol, 0.8 part of p-hydroxyacetophenone, 1.3 parts of an emulsifier, 1.8 parts of a thickening agent, 0.9 part of a surfactant, 2.3 parts of an arbutin supplementing agent, 0.5 part of tocopherol acetic acid, 1.2 parts of an antioxidant, 0.1 part of allantoin, 1.2 parts of potassium hydroxide, 0.6 part of sodium hyaluronate, 1.8 part of an anti-ultraviolet agent, 0.7 part of xanthan gum and 1.2 parts of an essence, and further comprises a whitening and freckle-removing component, and the whitening and freckle-removing component is prepared from 0.8 parts of nicotinamide, 1.3 parts of whitening agent I, 1.3 parts of whitening agent II, 1.84-355 parts of ascorbic acid and 1.5 parts of ascorbic acid;
the whitening agent I is prepared from the following components in parts by weight: 1.7 parts of grape fruit extract, 0.7 part of butanediol, 1.3 parts of glutathione and 1.7 parts of lactobacillus;
the whitening agent II is prepared from the following components in parts by weight: 0.6 part of 1, 2-pentanediol, 0.3 part of butanediol, 0.7 part of hydroxyphenylpropionamide benzoic acid and 1.4 parts of ascorbyl palmitate.
Further, the skin smoothing agent is prepared from the following components in parts by weight: 0.5 part of cyclopenta dimethyl silicone, 0.2 part of cyclotetra dimethyl silicone and 0.5 part of dimethiconol.
Further, the emulsifier is prepared from the following components in parts by weight: 18 parts of water, 2.5 parts of lecithin, 1.7 parts of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.6 part of cyclopenta polydimethylsiloxane, 1.4 parts of cyclohexasiloxane, 0.3 part of polydimethylsiloxane, 2.4 parts of glycerol, 1.3 parts of phenoxyethanol and 0.2 part of p-hydroxyacetophenone.
Further, the thickening agent is prepared from the following components in parts by weight: 3.6 parts of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer and 1.8 parts of cyclohexane.
Further, the surfactant is prepared from the following components in parts by weight: 3.1 parts of hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, 601.7 parts of polysorbate-601.7 parts of sorbitan isostearate and 15 parts of water.
Further, the water replenishing agent is prepared from the following components in parts by weight: 4.1 parts of sodium acrylate/sodium acryloyldimethyl taurate copolymer, 2.4 parts of isohexadecane, 26 parts of polysorbate-800.4 parts, 26 parts of water and 1.5 parts of sorbitan oleate.
Further, the antioxidant is prepared from the following components in parts by weight: 0.7 part of PEG-12 polydimethylsiloxane, 122.3 parts of polyethylene glycol-and 3.4 parts of tocopherol.
Further, the anti-ultraviolet agent is prepared from the following components in parts by weight: 3.9 parts of titanium dioxide and 4.7 parts of silica.
Referring to fig. 1, the preparation method of the multi-effect whitening and freckle-removing essence cream comprises the following steps:
s1, preparation aid: respectively weighing the components of the skin slipping agent, the emulsifier, the thickening agent, the surfactant, the moisturizing agent, the antioxidant and the anti-ultraviolet agent according to the proportion, sequentially preparing the finished product of the auxiliary agent by using a reaction kettle, and respectively storing the finished product in different storage tanks for later use;
s2, preparing the whitening agent: respectively weighing the components in the whitening agent I and the whitening agent II according to the proportion, and respectively and correspondingly preparing the whitening agent I and the whitening agent II by utilizing a reaction kettle A and a reaction kettle B, wherein the stirring rotation speed of the reaction kettle A is controlled to be 450r/min, the internal temperature is controlled to be 35 ℃, the internal pressure is controlled to be 0.8MPa, the stirring rotation speed of the reaction kettle B is controlled to be 550r/min, the internal temperature is controlled to be 45 ℃, and the internal pressure is controlled to be 0.9MPa, so that the finished products of the whitening agent I and the whitening agent II are respectively stored in two storage tanks and reserved for later use;
s3, preparation solvent: respectively weighing water, butanediol, cyclomethicone, propylene glycol, PEG/PPG-17/6 copolymer, 1, 2-hexanediol, p-hydroxyacetophenone, tocopheryl acetate, allantoin, potassium hydroxide, sodium hyaluronate, xanthan gum and essence according to a ratio, sequentially adding the weighed components into a reaction kettle in sequence, adjusting the rotating speed of the reaction kettle to be 650r/min, the internal temperature to be 60 ℃, the internal pressure to be 1.1MPa, uniformly stirring to obtain a matrix solvent, sequentially adding the water replenishing agent, the antioxidant, the anti-ultraviolet agent, the skin slipping agent and the surfactant prepared in the step S1 into the reaction kettle containing the matrix solvent, adjusting the rotating speed of the reaction kettle to be 800r/min, the internal temperature to be 40 ℃, and the internal pressure to be 0.7MPa to obtain the solvent, discharging for later use;
s4, emulsification and mixing: sequentially adding the solvent obtained in the step S3 and the whitening agent I and the whitening agent II obtained in the step S2 to an emulsifying machine, and then adding the emulsifier and the thickener prepared in the step S1 until complete emulsification and discharge to obtain a mixed emulsion;
s5, deslagging: transferring the mixed emulsion obtained in the step S4 to a filtering device to remove impurities contained in the mixed emulsion;
s6, concentration: adding the mixed emulsion subjected to slag removal in the step S5 into evaporation and concentration equipment to obtain finished product essence cream;
s7, packaging and warehousing: and (5) adding the finished product essence cream obtained in the step S6 into a filling machine, subpackaging into packaging bottles by the filling machine, and storing in storage.
Example 2
The invention provides a technical scheme that the multi-effect whitening and freckle-removing essence cream comprises basic components, wherein the basic components are prepared from 25.0 parts by weight of water, 0.8 part by weight of butanediol, 0.7 part by weight of cyclopolydimethylsiloxane, 1.6 parts by weight of propylene glycol, 2.1 parts by weight of PEG/PPG-17/6 copolymer, 3.0 parts by weight of skin slipping agent, 1.1 parts by weight of 1, 2-hexanediol, 1.1 parts by weight of p-hydroxyacetophenone, 1.6 parts by weight of emulsifier, 2.0 parts by weight of thickener, 1.5 parts by weight of surfactant, 2.7 parts by weight of arbutin, 0.9 part by weight of tocopherol acetic acid, 1.7 parts by weight of antioxidant, 0.3 part by weight of allantoin, 1.5 parts by weight of potassium hydroxide, 0.8 part by weight of sodium hyaluronate, 2.3 parts by weight of anti-ultraviolet agent, 1.0 part by weight of xanthan gum and 1.6 parts by weight of essence, and further comprises whitening and freckle-removing components, wherein the whitening and freckle-removing components are prepared from 1.5 parts by weight of nicotinamide, 2.5 parts by weight of whitening agent I, 2.5 parts by weight of;
the whitening agent I is prepared from the following components in parts by weight: 2.4 parts of grape fruit extract, 1.3 parts of butanediol, 2.0 parts of glutathione and 2.4 parts of lactobacillus;
the whitening agent II is prepared from the following components in parts by weight: 1.1 parts of 1, 2-pentanediol, 0.8 parts of butanediol, 1.2 parts of hydroxyphenylpropionamide benzoic acid and 2.3 parts of ascorbyl palmitate.
Further, the skin smoothing agent is prepared from the following components in parts by weight: 1.2 parts of cyclopenta dimethyl silicone, 0.5 part of cyclotetra dimethyl silicone and 1.2 parts of dimethiconol.
Further, the emulsifier is prepared from the following components in parts by weight: 23 parts of water, 3.0 parts of lecithin, 2.7 parts of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 1.3 parts of cyclopenta polydimethylsiloxane, 1.8 parts of cyclohexasiloxane, 0.7 part of polydimethylsiloxane, 2.9 parts of glycerol, 1.7 parts of phenoxyethanol and 0.7 part of p-hydroxyacetophenone.
Further, the thickening agent is prepared from the following components in parts by weight: 4.4 parts of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer and 2.5 parts of cyclohexane.
Further, the surfactant is prepared from the following components in parts by weight: 4.3 parts of hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, 602.6 parts of polysorbate, 1.4 parts of sorbitan isostearate and 21 parts of water.
Further, the water replenishing agent is prepared from the following components in parts by weight: 6.3 parts of sodium acrylate/sodium acryloyldimethyl taurate copolymer, 3.1 parts of isohexadecane, 800.9 parts of polysorbate-800.9 parts, 30 parts of water and 2.4 parts of sorbitan oleate.
Further, the antioxidant is prepared from the following components in parts by weight: 1.3 parts of PEG-12 polydimethylsiloxane, 122.8 parts of polyethylene glycol-and 5.2 parts of tocopherol.
Further, the anti-ultraviolet agent is prepared from the following components in parts by weight: 5.8 parts of titanium dioxide and 7.1 parts of silica.
Referring to fig. 1, the preparation method of the multi-effect whitening and freckle-removing essence cream comprises the following steps:
s1, preparation aid: respectively weighing the components of the skin slipping agent, the emulsifier, the thickening agent, the surfactant, the moisturizing agent, the antioxidant and the anti-ultraviolet agent according to the proportion, sequentially preparing the finished product of the auxiliary agent by using a reaction kettle, and respectively storing the finished product in different storage tanks for later use;
s2, preparing the whitening agent: weighing the components in the whitening agent I and the whitening agent II respectively according to the proportion, and preparing the whitening agent I and the whitening agent II respectively and correspondingly by utilizing a reaction kettle A and a reaction kettle B, wherein the stirring rotation speed of the reaction kettle A is controlled to be 600r/min, the internal temperature is controlled to be 50 ℃, the internal pressure is controlled to be 1.1MPa, the stirring rotation speed of the reaction kettle B is controlled to be 750r/min, the internal temperature is controlled to be 60 ℃, the internal pressure is controlled to be 1.2MPa, so that the finished products of the whitening agent I and the whitening agent II are respectively stored in two storage tanks and reserved for later use;
s3, preparation solvent: respectively weighing water, butanediol, cyclomethicone, propylene glycol, PEG/PPG-17/6 copolymer, 1, 2-hexanediol, p-hydroxyacetophenone, tocopheryl acetate, allantoin, potassium hydroxide, sodium hyaluronate, xanthan gum and essence according to a ratio, sequentially adding the weighed components into a reaction kettle in sequence, adjusting the rotating speed of the reaction kettle to 700r/min, the internal temperature to 75 ℃ and the internal pressure to 1.3MPa, uniformly stirring to obtain a matrix solvent, sequentially adding the water replenishing agent, the antioxidant, the anti-ultraviolet agent, the skin slipping agent and the surfactant prepared in the step S1 into the reaction kettle containing the matrix solvent, adjusting the rotating speed of the reaction kettle to 950r/min, the internal temperature to 50 ℃ and the internal pressure to 1.2MPa to obtain the solvent, discharging for later use;
s4, emulsification and mixing: sequentially adding the solvent obtained in the step S3 and the whitening agent I and the whitening agent II obtained in the step S2 to an emulsifying machine, and then adding the emulsifier and the thickener prepared in the step S1 until complete emulsification and discharge to obtain a mixed emulsion;
s5, deslagging: transferring the mixed emulsion obtained in the step S4 to a filtering device to remove impurities contained in the mixed emulsion;
s6, concentration: adding the mixed emulsion subjected to slag removal in the step S5 into evaporation and concentration equipment to obtain finished product essence cream;
s7, packaging and warehousing: and (5) adding the finished product essence cream obtained in the step S6 into a filling machine, subpackaging into packaging bottles by the filling machine, and storing in storage.
Example 3
The invention provides a technical scheme that the multi-effect whitening and freckle-removing essence cream comprises a basic component, wherein the basic component is prepared from, by weight, 23.0 parts of water, 0.6 part of butanediol, 0.5 part of cyclopolydimethylsiloxane, 1.5 parts of propylene glycol, 1.8 parts of PEG/PPG-17/6 copolymer, 2.7 parts of a skin slipping agent, 0.9 part of 1, 2-hexanediol, 0.9 part of p-hydroxyacetophenone, 1.5 parts of an emulsifier, 1.9 parts of a thickener, 1.3 parts of a surfactant, 2.6 parts of an arbutin aqua, 0.6 part of tocopherol acetic acid, 1.5 parts of an antioxidant, 0.2 part of allantoin, 1.4 parts of potassium hydroxide, 0.7 part of sodium hyaluronate, 2.0 parts of an anti-ultraviolet agent, 0.8 part of xanthan gum and 1.5 parts of an essence, and further comprises a whitening and freckle-removing component, and the whitening and freckle-removing component is prepared from 1.4 parts of nicotinamide, 2.1.1.1 part of a whitening agent I, 2.4 parts of a whitening agent II, 2.84-358 parts of ascorbic acid and 1.8 parts of ascorbic acid;
the whitening agent I is prepared from the following components in parts by weight: 2.3 parts of grape fruit extract, 1.1 parts of butanediol, 1.8 parts of glutathione and 2.3 parts of lactobacillus;
the whitening agent II is prepared from the following components in parts by weight: 1.0 part of 1, 2-pentanediol, 0.7 part of butanediol, 1.0 part of hydroxyphenylpropionamide benzoic acid and 2.1 parts of ascorbyl palmitate.
Further, the skin smoothing agent is prepared from the following components in parts by weight: 1.1 parts of cyclopenta dimethyl silicone polymer, 0.3 parts of cyclotetra dimethyl silicone polymer and 1.7 parts of dimethiconol.
Further, the emulsifier is prepared from the following components in parts by weight: 20 parts of water, 2.8 parts of lecithin, 2.0 parts of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 1.1 parts of cyclopenta polydimethylsiloxane, 1.5 parts of cyclohexasiloxane, 0.6 part of polydimethylsiloxane, 2.5 parts of glycerol, 1.5 parts of phenoxyethanol and 0.5 part of p-hydroxyacetophenone.
Further, the thickening agent is prepared from the following components in parts by weight: 4.0 parts of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer and 2.0 parts of cyclohexane.
Further, the surfactant is prepared from the following components in parts by weight: 3.9 parts of hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, 602.5 parts of polysorbate-602.5 parts of sorbitan isostearate and 20 parts of water.
Further, the water replenishing agent is prepared from the following components in parts by weight: 5.1 parts of sodium acrylate/sodium acryloyldimethyl taurate copolymer, 2.9 parts of isohexadecane, 800.6 parts of polysorbate-water, 28 parts of water and 2.0 parts of sorbitan oleate.
Further, the antioxidant is prepared from the following components in parts by weight: 1.1 parts of PEG-12 polydimethylsiloxane, 122.5 parts of polyethylene glycol-and 4.5 parts of tocopherol.
Further, the anti-ultraviolet agent is prepared from the following components in parts by weight: 5.0 parts of titanium dioxide and 6.5 parts of silica.
Referring to fig. 1, the preparation method of the multi-effect whitening and freckle-removing essence cream comprises the following steps:
s1, preparation aid: respectively weighing the components of the skin slipping agent, the emulsifier, the thickening agent, the surfactant, the moisturizing agent, the antioxidant and the anti-ultraviolet agent according to the proportion, sequentially preparing the finished product of the auxiliary agent by using a reaction kettle, and respectively storing the finished product in different storage tanks for later use;
s2, preparing the whitening agent: weighing the components in the whitening agent I and the whitening agent II respectively according to the proportion, and preparing the whitening agent I and the whitening agent II respectively and correspondingly by utilizing a reaction kettle A and a reaction kettle B, wherein the stirring rotation speed of the reaction kettle A is controlled to be 550r/min, the internal temperature is controlled to be 45 ℃, the internal pressure is controlled to be 1.0MPa, the stirring rotation speed of the reaction kettle B is controlled to be 700r/min, the internal temperature is controlled to be 55 ℃, the internal pressure is controlled to be 1.1MPa, so that the finished products of the whitening agent I and the whitening agent II are respectively stored in two storage tanks and reserved for later use;
s3, preparation solvent: respectively weighing water, butanediol, cyclomethicone, propylene glycol, PEG/PPG-17/6 copolymer, 1, 2-hexanediol, p-hydroxyacetophenone, tocopheryl acetate, allantoin, potassium hydroxide, sodium hyaluronate, xanthan gum and essence according to a ratio, sequentially adding the weighed components into a reaction kettle in sequence, adjusting the rotating speed of the reaction kettle to 680r/min, the internal temperature to 70 ℃, the internal pressure to 1.2MPa, uniformly stirring to obtain a matrix solvent, sequentially adding the water replenishing agent, the antioxidant, the anti-ultraviolet agent, the skin slipping agent and the surfactant prepared in the step S1 into the reaction kettle containing the matrix solvent, adjusting the rotating speed of the reaction kettle to 900r/min, the internal temperature to 48 ℃, and the internal pressure to 1.1MPa to obtain the solvent, discharging for later use;
s4, emulsification and mixing: sequentially adding the solvent obtained in the step S3 and the whitening agent I and the whitening agent II obtained in the step S2 to an emulsifying machine, and then adding the emulsifier and the thickener prepared in the step S1 until complete emulsification and discharge to obtain a mixed emulsion;
s5, deslagging: transferring the mixed emulsion obtained in the step S4 to a filtering device to remove impurities contained in the mixed emulsion;
s6, concentration: adding the mixed emulsion subjected to slag removal in the step S5 into evaporation and concentration equipment to obtain finished product essence cream;
s7, packaging and warehousing: and (5) adding the finished product essence cream obtained in the step S6 into a filling machine, subpackaging into packaging bottles by the filling machine, and storing in storage.
Comparative test
In order to verify the practical use effect of the essence cream prepared by the three examples, a certain manufacturer makes the following comparative tests:
selecting three male and female human bodies with the ages of 25, 35 and 50 respectively, wherein the skin characteristics of the male and female human bodies with the ages of 25, 35 and 50 are oily, neutral and dry respectively, so that the three human bodies and the existing essence cream are used by the human bodies respectively, the satisfaction degree of each human body is accessed respectively in the stage of using the three examples for 30 days, and the following results are obtained;
the age was 25 years and the skin characteristics corresponded to the results of satisfaction in three male subjects presenting an oily, neutral and dry appearance, as shown in table 1:
TABLE 1
The age was 25 years and the skin characteristics corresponded to the results of satisfaction in three female subjects who presented as oily, neutral and dry, as shown in table 2:
TABLE 2
The age was 35 years and the skin characteristics corresponded to the results of satisfaction in three male subjects presenting an oily, neutral and dry appearance, as shown in table 3:
TABLE 3
Age 35 years and skin characteristics correspond to the results of satisfaction in three female subjects presenting oiliness, neutrality and dryness, as shown in table 4:
TABLE 4
The age was 50 years and the skin characteristics corresponded to the results of satisfaction in three male subjects presenting an oily, neutral and dry appearance, as shown in table 5:
TABLE 5
Age 50 years and skin characteristics correspond to the results of satisfaction in three female subjects presenting oiliness, neutrality and dryness, as shown in table 6:
TABLE 6
In summary, from the physical data, the essence creams prepared in the three examples are suitable for the users with different skin conditions, after trial 30, the satisfaction rate of the visit was much higher than the essences present in the prior art, and the essence in the three embodiments has higher effect in embodiment 3 than the products prepared in the other two embodiments, furthermore, the use effect of women is higher than that of men from the viewpoint of gender, the satisfaction of the trial population of 50 years is higher than that of the trial population of 25 years from the viewpoint of age, and the use effect of the trial population with oily skin is better than that of the trial population with neutral and dry skin from the viewpoint of skin characteristics, the essence cream prepared by the three embodiments has good public praise on the aspects of whitening and melanin inhibiting effects.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (9)
1. A multi-effect whitening and freckle-removing essence cream comprises the following components, by weight, 20.0-25.0 parts of water, 0.3-0.8 part of butanediol, 0.4-0.7 part of cyclomethicone, 1.2-1.6 parts of propylene glycol, 1.7-2.1 parts of PEG/PPG-17/6 copolymer, 2.5-3.0 parts of skin slipping agent, 0.8-1.1 parts of 1, 2-hexanediol, 0.8-1.1 parts of p-hydroxyacetophenone, 1.3-1.6 parts of emulsifier, 1.8-2.0 parts of thickener, 0.9-1.5 parts of surfactant, 2.3-2.7 parts of moisturizing agent, 0.5-0.9 part of tocopherol acetic acid, 1.2-1.7 parts of antioxidant, 0.1-0.3 part of allantoin, 1.2-1.5 parts of potassium hydroxide, 0.6-0.8 part of hyaluronic acid, 0.84-0.1.6 part of freckle-removing agent, 1.2 parts of xanthan gum, 1.5-1.6 parts of whitening essence, 1.5 parts of whitening and 1.2-1.5 parts of skin whitening essence, wherein the components comprise the following components, 1.2-2.8 parts of freckle removing components, 2.5 parts of spot removing essence, 2.1.5 parts of spot removing components, 2-1.5 parts of spot, 2 parts of spot removing essence, 2.5 parts of 1.5 parts of 1.6 parts of vitamin I, 2-1.5 parts of skin whitening essence, 2 parts of skin;
the whitening agent I is prepared from the following components in parts by weight: 1.7-2.4 parts of grape fruit extract, 0.7-1.3 parts of butanediol, 1.3-2.0 parts of glutathione and 1.7-2.4 parts of lactobacillus;
the whitening agent II is prepared from the following components in parts by weight: 0.6-1.1 parts of 1, 2-pentanediol, 0.3-0.8 part of butanediol, 0.7-1.2 parts of hydroxyphenylpropionamide benzoic acid and 1.4-2.3 parts of ascorbyl palmitate.
2. The multi-effect whitening and freckle-removing essence cream according to claim 1, which is characterized in that the skin smoothing agent is prepared from the following components in parts by weight: 0.5-1.2 parts of cyclopenta dimethyl siloxane, 0.2-0.5 part of cyclotetra dimethyl siloxane and 0.5-1.2 parts of dimethiconol.
3. The multi-effect whitening and freckle-removing essence cream according to claim 1, wherein the emulsifier is prepared from the following components in parts by weight: 18-23 parts of water, 2.5-3.0 parts of lecithin, 1.7-2.7 parts of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.6-1.3 parts of cyclopenta polydimethylsiloxane, 1.4-1.8 parts of cyclohexasiloxane, 0.3-0.7 part of polydimethylsiloxane, 2.4-2.9 parts of glycerol, 1.3-1.7 parts of phenoxyethanol and 0.2-0.7 part of p-hydroxyacetophenone.
4. The multi-effect whitening and freckle-removing essence cream according to claim 1, characterized in that the thickener is prepared from the following components in parts by weight: 3.6-4.4 parts of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer and 1.8-2.5 parts of cyclohexane.
5. The multi-effect whitening and freckle-removing essence cream according to claim 1, characterized in that the surfactant is prepared from the following components in parts by weight: 3.1-4.3 parts of hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, 2.6-2.78 parts of polysorbate-601.7, 0.9-1.4 parts of sorbitan isostearate and 15-21 parts of water.
6. The multi-effect whitening and freckle-removing essence cream according to claim 1, which is characterized in that the moisturizing agent is prepared from the following components in parts by weight: 4.1-6.3 parts of sodium acrylate/sodium acryloyldimethyl taurate copolymer, 2.4-3.1 parts of isohexadecane, 0.9-0.78 part of polysorbate-800.4, 26-30 parts of water and 1.5-2.4 parts of sorbitan oleate.
7. The multi-effect whitening and freckle-removing essence cream according to claim 1, characterized in that the antioxidant is prepared from the following components in parts by weight: 0.7-1.3 parts of PEG-12 polydimethylsiloxane, 122.3-2.8 parts of polyethylene glycol-3 and 3.4-5.2 parts of tocopherol.
8. The multi-effect whitening and freckle-removing essence cream according to claim 1, which is characterized in that the anti-ultraviolet agent is prepared from the following components in parts by weight: 3.9-5.8 parts of titanium dioxide and 4.7-7.1 parts of silica.
9. The preparation method of the multi-effect whitening and freckle-removing essence cream according to any one of claims 1 to 8, which is characterized by comprising the following steps of:
s1, preparation aid: respectively weighing the components of the skin slipping agent, the emulsifier, the thickening agent, the surfactant, the moisturizing agent, the antioxidant and the anti-ultraviolet agent according to the proportion, sequentially preparing the finished product of the auxiliary agent by using a reaction kettle, and respectively storing the finished product in different storage tanks for later use;
s2, preparing the whitening agent: respectively weighing the components in the whitening agent I and the whitening agent II according to the proportion, and respectively and correspondingly preparing the whitening agent I and the whitening agent II by utilizing a reaction kettle A and a reaction kettle B, wherein the stirring rotating speed of the reaction kettle A is controlled to be 450-ion 600r/min, the internal temperature is controlled to be 35-50 ℃, the internal pressure is controlled to be 0.8-1.1MPa, the stirring rotating speed of the reaction kettle B is controlled to be 550-ion 750r/min, the internal temperature is controlled to be 45-60 ℃, and the internal pressure is controlled to be 0.9-1.2MPa, so as to obtain the finished products of the whitening agent I and the whitening agent II, then respectively storing the finished products in two storage tanks, and reserving the finished products for later use;
s3, preparation solvent: respectively weighing water, butanediol, cyclomethicone, propylene glycol, PEG/PPG-17/6 copolymer, 1, 2-hexanediol, p-hydroxyacetophenone, tocopheryl acetate, allantoin, potassium hydroxide, sodium hyaluronate, xanthan gum and essence according to the proportion, sequentially adding the weighed components into a reaction kettle according to the sequence of the components, adjusting the rotating speed of the reaction kettle to be 650-700r/min, controlling the internal temperature to be 60-75 ℃, controlling the internal pressure to be 1.1-1.3MPa, uniformly stirring to obtain a matrix solvent, sequentially adding the water replenishing agent, the antioxidant, the anti-ultraviolet agent, the skin lubricant and the surfactant prepared in the step S1 into the reaction kettle containing the matrix solvent, adjusting the rotating speed of the reaction kettle to be 800-950r/min, controlling the internal temperature to be 40-50 ℃, controlling the internal pressure to be 0.7-1.2MPa, obtaining a solvent, and discharging for later use;
s4, emulsification and mixing: sequentially adding the solvent obtained in the step S3 and the whitening agent I and the whitening agent II obtained in the step S2 to an emulsifying machine, and then adding the emulsifier and the thickener prepared in the step S1 until complete emulsification and discharge to obtain a mixed emulsion;
s5, deslagging: transferring the mixed emulsion obtained in the step S4 to a filtering device to remove impurities contained in the mixed emulsion;
s6, concentration: adding the mixed emulsion subjected to slag removal in the step S5 into evaporation and concentration equipment to obtain finished product essence cream;
s7, packaging and warehousing: and (5) adding the finished product essence cream obtained in the step S6 into a filling machine, subpackaging into packaging bottles by the filling machine, and storing in storage.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010455781.9A CN111467279A (en) | 2020-05-26 | 2020-05-26 | Multi-effect whitening and freckle-removing essence cream and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010455781.9A CN111467279A (en) | 2020-05-26 | 2020-05-26 | Multi-effect whitening and freckle-removing essence cream and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111467279A true CN111467279A (en) | 2020-07-31 |
Family
ID=71760258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010455781.9A Pending CN111467279A (en) | 2020-05-26 | 2020-05-26 | Multi-effect whitening and freckle-removing essence cream and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111467279A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111920756A (en) * | 2020-09-11 | 2020-11-13 | 广州芊植本草化妆品有限公司 | Nicotinamide whitening and repairing mask, essence of mask and preparation method of essence |
| WO2022210148A1 (en) * | 2021-04-02 | 2022-10-06 | 株式会社 資生堂 | Cosmetic preparation |
| CN115770196A (en) * | 2022-11-30 | 2023-03-10 | 广州市婷采化妆品有限公司 | Multi-effect skin care product capable of whitening and removing freckles as well as preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108379160A (en) * | 2018-04-20 | 2018-08-10 | 安徽怡人生物科技有限公司 | A kind of freckle removing and whitening frost and preparation method thereof |
| CN109010216A (en) * | 2018-10-11 | 2018-12-18 | 广州怡嘉生物科技有限公司 | A kind of whitening cosmetics and preparation method thereof |
| CN110638720A (en) * | 2019-10-29 | 2020-01-03 | 浙江英树生物科技有限公司 | Plant moisturizing and repairing lotion and preparation method thereof |
-
2020
- 2020-05-26 CN CN202010455781.9A patent/CN111467279A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108379160A (en) * | 2018-04-20 | 2018-08-10 | 安徽怡人生物科技有限公司 | A kind of freckle removing and whitening frost and preparation method thereof |
| CN109010216A (en) * | 2018-10-11 | 2018-12-18 | 广州怡嘉生物科技有限公司 | A kind of whitening cosmetics and preparation method thereof |
| CN110638720A (en) * | 2019-10-29 | 2020-01-03 | 浙江英树生物科技有限公司 | Plant moisturizing and repairing lotion and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 广州协和生物医药科技有限公司: "斑小将雪肌修复精华乳", 《国产非特殊用途化妆品备案服务平台》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111920756A (en) * | 2020-09-11 | 2020-11-13 | 广州芊植本草化妆品有限公司 | Nicotinamide whitening and repairing mask, essence of mask and preparation method of essence |
| WO2022210148A1 (en) * | 2021-04-02 | 2022-10-06 | 株式会社 資生堂 | Cosmetic preparation |
| CN115770196A (en) * | 2022-11-30 | 2023-03-10 | 广州市婷采化妆品有限公司 | Multi-effect skin care product capable of whitening and removing freckles as well as preparation method and application thereof |
| CN115770196B (en) * | 2022-11-30 | 2023-11-21 | 广州市婷采化妆品有限公司 | Multi-effect whitening and freckle-removing skin care product and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN111467279A (en) | Multi-effect whitening and freckle-removing essence cream and preparation method thereof | |
| CN113616566B (en) | Skin care essence for tightening skin and preparation method thereof | |
| EP1879549B1 (en) | Personal care compositions comprising a dipeptide | |
| JP4099173B2 (en) | Cosmetic or dermopharmaceutical composition comprising kombucha | |
| CN103735444B (en) | A kind of Multifunctional CC cream | |
| CN104856892A (en) | Cosmetic or skin care product preparation rich in growth factors and preparation method therefor | |
| US20150182447A1 (en) | Method for improving skin condition comprising six steps and system therefor | |
| CN104906028B (en) | It is a kind of that there is the fermented product composition for improving skin problem and its application | |
| CN102274141B (en) | Herba selaginellae revival moisturizing cream and preparation method thereof | |
| CN111671685A (en) | Whitening and freckle-removing composition, whitening and freckle-removing cream and preparation method thereof | |
| CN109172390A (en) | A kind of multiple-effect of the extract containing Ganoderma Sinense is preserved youthful looks lotion and preparation method thereof | |
| CN106727252A (en) | A kind of safety-type elite formula of liquid and its technique with whitening effect | |
| CN112353725A (en) | Efficacy composition in eye cream, eye cream and preparation method thereof | |
| CN110302091B (en) | Composition containing nicotinamide adenine dinucleotide for resisting skin aging and preparation method and application thereof | |
| CN109044941A (en) | A kind of skin-tightening nourishes moisture-keeping composition and its preparation method and application | |
| CN115154375A (en) | Stable cleaning composition with repairing and relieving effects | |
| CN108434088A (en) | A kind of collagen polypeptide U.S. flesh facial mask and preparation method thereof | |
| JPH0676311B2 (en) | Topical use of 3-phenylacetylamino-2,6-piperidinedione for the treatment of skin wrinkles and hyperpigmentation. | |
| CN111000784A (en) | Freckle-removing night cream and preparation method thereof | |
| CN110559195A (en) | Mask powder with whitening and anti-aging functions and preparation method thereof | |
| CN101524317B (en) | Skin-care cosmetic containing nonane diacid for dispelling freckles | |
| CN111759762A (en) | Black eye removing composition, essence and preparation method thereof | |
| CN106361667B (en) | Snake oil ointment | |
| CN102266275A (en) | Application of refined deer oil in preparation of anti-wrinkle cosmetics | |
| KR101208013B1 (en) | A skin-care agent containing mycoleptodonoides aitchisonii mycelium extract |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20200731 |