CN111467270A - Skin care product containing aminobutyric acid - Google Patents
Skin care product containing aminobutyric acid Download PDFInfo
- Publication number
- CN111467270A CN111467270A CN202010304748.6A CN202010304748A CN111467270A CN 111467270 A CN111467270 A CN 111467270A CN 202010304748 A CN202010304748 A CN 202010304748A CN 111467270 A CN111467270 A CN 111467270A
- Authority
- CN
- China
- Prior art keywords
- parts
- component
- aminobutyric acid
- skin care
- care product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 title claims abstract description 71
- 229940124277 aminobutyric acid Drugs 0.000 title claims abstract description 68
- 239000000284 extract Substances 0.000 claims abstract description 52
- XMWRBQBLMFGWIX-UHFFFAOYSA-N C60 fullerene Chemical compound C12=C3C(C4=C56)=C7C8=C5C5=C9C%10=C6C6=C4C1=C1C4=C6C6=C%10C%10=C9C9=C%11C5=C8C5=C8C7=C3C3=C7C2=C1C1=C2C4=C6C4=C%10C6=C9C9=C%11C5=C5C8=C3C3=C7C1=C1C2=C4C6=C2C9=C5C3=C12 XMWRBQBLMFGWIX-UHFFFAOYSA-N 0.000 claims abstract description 27
- 229910003472 fullerene Inorganic materials 0.000 claims abstract description 27
- 229940041514 candida albicans extract Drugs 0.000 claims abstract description 23
- 239000012138 yeast extract Substances 0.000 claims abstract description 23
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims abstract description 22
- 241000206572 Rhodophyta Species 0.000 claims abstract description 20
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 20
- 235000004727 Opuntia ficus indica Nutrition 0.000 claims abstract description 17
- 240000009297 Opuntia ficus-indica Species 0.000 claims abstract description 17
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 57
- BTFJIXJJCSYFAL-UHFFFAOYSA-N icosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCO BTFJIXJJCSYFAL-UHFFFAOYSA-N 0.000 claims description 51
- 150000002148 esters Chemical class 0.000 claims description 40
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 38
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims description 38
- NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 claims description 34
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 claims description 26
- 229920005573 silicon-containing polymer Polymers 0.000 claims description 26
- 241000221095 Simmondsia Species 0.000 claims description 23
- 235000004433 Simmondsia californica Nutrition 0.000 claims description 23
- -1 pentaerythritol tetra (ethyl hexanoate) ester Chemical class 0.000 claims description 23
- XUJLWPFSUCHPQL-UHFFFAOYSA-N 11-methyldodecan-1-ol Chemical compound CC(C)CCCCCCCCCCO XUJLWPFSUCHPQL-UHFFFAOYSA-N 0.000 claims description 19
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 19
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 19
- XZOYHFBNQHPJRQ-UHFFFAOYSA-N 7-methyloctanoic acid Chemical compound CC(C)CCCCCC(O)=O XZOYHFBNQHPJRQ-UHFFFAOYSA-N 0.000 claims description 19
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 19
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims description 19
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims description 19
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims description 19
- 229920001353 Dextrin Polymers 0.000 claims description 19
- 239000004375 Dextrin Substances 0.000 claims description 19
- BIVBRWYINDPWKA-VLQRKCJKSA-L Glycyrrhizinate dipotassium Chemical compound [K+].[K+].O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@](C)(CC[C@@]5(CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C)C)C(O)=O)C([O-])=O)[C@@H]1O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]1O BIVBRWYINDPWKA-VLQRKCJKSA-L 0.000 claims description 19
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 claims description 19
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 19
- 235000021355 Stearic acid Nutrition 0.000 claims description 19
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 19
- 229960000458 allantoin Drugs 0.000 claims description 19
- 229960003237 betaine Drugs 0.000 claims description 19
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- 235000019425 dextrin Nutrition 0.000 claims description 19
- 229940101029 dipotassium glycyrrhizinate Drugs 0.000 claims description 19
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims description 19
- IPCSVZSSVZVIGE-UHFFFAOYSA-M hexadecanoate Chemical compound CCCCCCCCCCCCCCCC([O-])=O IPCSVZSSVZVIGE-UHFFFAOYSA-M 0.000 claims description 19
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims description 19
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims description 19
- AEIJTFQOBWATKX-UHFFFAOYSA-N octane-1,2-diol Chemical compound CCCCCCC(O)CO AEIJTFQOBWATKX-UHFFFAOYSA-N 0.000 claims description 19
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims description 19
- 229920003229 poly(methyl methacrylate) Polymers 0.000 claims description 19
- 239000004926 polymethyl methacrylate Substances 0.000 claims description 19
- RMGVATURDVPNOZ-UHFFFAOYSA-M potassium;hexadecyl hydrogen phosphate Chemical compound [K+].CCCCCCCCCCCCCCCCOP(O)([O-])=O RMGVATURDVPNOZ-UHFFFAOYSA-M 0.000 claims description 19
- 239000000377 silicon dioxide Substances 0.000 claims description 19
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 19
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 19
- 239000008117 stearic acid Substances 0.000 claims description 19
- 229940042585 tocopherol acetate Drugs 0.000 claims description 19
- VKIJBOMCWLTQBD-UHFFFAOYSA-N benzoic acid N-(2-hydroxyphenyl)propanamide Chemical compound C(C1=CC=CC=C1)(=O)O.C(CC)(=O)NC1=C(C=CC=C1)O VKIJBOMCWLTQBD-UHFFFAOYSA-N 0.000 claims description 18
- MFYAQFYIDXXKQG-MLCQCVOFSA-N (2s)-2-[[(2s)-4-amino-2-[[(2s)-2-[[(2s)-2-(hexadecanoylamino)-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-4-oxobutanoyl]amino]propanoic acid Chemical compound CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(O)=O MFYAQFYIDXXKQG-MLCQCVOFSA-N 0.000 claims description 17
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims description 17
- 108010075308 N-palmitoyl-seryl-seryl-asparaginyl-alanine Proteins 0.000 claims description 17
- DRRMRHKHTQRWMB-UHFFFAOYSA-N [3-(2-ethylhexanoyloxy)-2,2-bis(2-ethylhexanoyloxymethyl)propyl] 2-ethylhexanoate Chemical compound CCCCC(CC)C(=O)OCC(COC(=O)C(CC)CCCC)(COC(=O)C(CC)CCCC)COC(=O)C(CC)CCCC DRRMRHKHTQRWMB-UHFFFAOYSA-N 0.000 claims description 17
- 235000013871 bee wax Nutrition 0.000 claims description 17
- 239000012166 beeswax Substances 0.000 claims description 17
- 229960000735 docosanol Drugs 0.000 claims description 17
- 229930182478 glucoside Natural products 0.000 claims description 17
- 229940075529 glyceryl stearate Drugs 0.000 claims description 17
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims description 17
- 229940100460 peg-100 stearate Drugs 0.000 claims description 17
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 claims description 17
- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 claims description 17
- 241000195493 Cryptophyta Species 0.000 claims description 16
- 238000002360 preparation method Methods 0.000 claims description 13
- 229940082500 cetostearyl alcohol Drugs 0.000 claims description 12
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 claims description 12
- 241000219357 Cactaceae Species 0.000 claims description 8
- 239000003995 emulsifying agent Substances 0.000 claims description 8
- 238000002156 mixing Methods 0.000 claims description 6
- 229940081733 cetearyl alcohol Drugs 0.000 claims description 5
- 239000004902 Softening Agent Substances 0.000 claims description 4
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 4
- 239000003974 emollient agent Substances 0.000 claims description 4
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 4
- 241000168525 Haematococcus Species 0.000 claims description 3
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- IHRKJQSLKLYWBQ-QKDODKLFSA-N (2s)-2-[[(2s)-1-[(2s)-5-amino-2-[[2-(hexadecanoylamino)acetyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid Chemical compound CCCCCCCCCCCCCCCC(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O IHRKJQSLKLYWBQ-QKDODKLFSA-N 0.000 claims description 2
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- 210000003491 skin Anatomy 0.000 abstract description 60
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- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
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- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
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- QWCKQJZIFLGMSD-UHFFFAOYSA-N alpha-aminobutyric acid Chemical compound CCC(N)C(O)=O QWCKQJZIFLGMSD-UHFFFAOYSA-N 0.000 description 2
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- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
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- 241000195620 Euglena Species 0.000 description 1
- 206010016807 Fluid retention Diseases 0.000 description 1
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- KIUVQMGRTDPAFR-UHFFFAOYSA-N benzoic acid 2-hydroxy-2-phenylpropanamide Chemical compound C(C1=CC=CC=C1)(=O)O.OC(C(=O)N)(C)C1=CC=CC=C1 KIUVQMGRTDPAFR-UHFFFAOYSA-N 0.000 description 1
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- 230000002708 enhancing effect Effects 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 229960003692 gamma aminobutyric acid Drugs 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
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- 239000000419 plant extract Substances 0.000 description 1
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- 230000003449 preventive effect Effects 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
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- 239000000126 substance Substances 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
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- 229940046009 vitamin E Drugs 0.000 description 1
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Classifications
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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Abstract
The invention discloses an aminobutyric acid skin care product. The invention contains the beer yeast extract, the opuntia ficus-indica stem extract, the rhodophyta extract, the aminobutyric acid and the fullerene, can enhance cell repair, promote skin cell activation and effectively resist aging. In addition, the skin care product is obviously superior to cosmetics which are not composed according to the formula with the specific content in the aspects of antioxidant activity, skin brightness improvement and hydration degree improvement, and the defect of single component effect in the existing skin care product of aminobutyric acid is overcome.
Description
Technical Field
The invention relates to the field of cosmetics, and particularly relates to an aminobutyric acid skin care product.
Background
With the improvement of the living standard of people, people pursue higher and higher quality of life. Skin care, especially basic care, has become a concern. The skin of hands and eyes is more prone to aging than other human skins, and as the human body ages, the skin at the position loses elasticity continuously and is more prone to stimulation. Therefore, the quality requirements of people for various skin care products are gradually higher, and various skin care products containing a large amount of natural organic matter components are very popular with people due to good skin repairing function.
The common wrinkle-removing product can be used for a period of time to feel the wrinkle-removing effect, and the consumer confidence of the product is easily influenced because the wrinkle-removing product is not intuitive. And various skin problems such as peeling, fine lines, wrinkles, water shortage, roughness, pimples and color spots caused by cold or other various reasons are becoming more serious due to the usual living habits and working pressure. The existing general skin care products generally contain vitamin E and vitamin B, and have single effect. Moreover, most skin care products on the market are emulsion systems, and the skin care products are easy to generate sticky feeling after being used, so that the skin care products are not suitable for every consumer, and the skin care products suitable for the public must be developed in a targeted manner.
Therefore, how to produce the moisturizing skin care product containing plant components and aminobutyric acid improves the reproduction and regeneration of the active polypeptide molecules in human bodies to control cells, fundamentally promotes the regeneration of the cells in the epidermis, and has important practical significance.
Disclosure of Invention
The invention aims to provide an aminobutyric acid skin care product.
The technical scheme adopted by the invention is as follows:
in a first aspect of the present invention, there is provided:
an aminobutyric acid skin care product comprises the following components:
and (2) component A: emulsifier, stearic acid, jojoba esters, pentaerythritol tetra (ethyl hexanoate) ester, sodium hyaluronate, tocopherol acetate, polymethyl methacrylate, isotridecanol isononanoate;
and (B) component: dextrin palmitate, silica, emollients;
and (3) component C: acrylic acid/C10-30 alkanol acrylate crosspolymer, allantoin, dipotassium glycyrrhizinate, betaine, potassium cetyl phosphate, glycerol, dipropylene glycol;
and (3) component D: triethanolamine;
and (3) component E: hydroxyphenyl propionamide benzoic acid, palmitoyl tetrapeptide-7, brewer's yeast extract, cactus stem extract, fullerene, essence, 1, 2-pentanediol, and caprylyl glycol;
and (3) component F: aminobutyric acid;
a component G: extract of Haematococcus sp.
The Saccharomyces cerevisiae extract is the fermentation product of Saccharomyces cerevisiae. It comprises metabolites, cytoplasm, cell wall and polysaccharide complexes. Such active substances obtained by means of biotechnology are able to support specifically the protective and reparative matrix of the skin itself. Can provide preventive care for normal skin and damaged skin, protect the damage caused by ultraviolet rays by enhancing the cell endogenous enzyme to promote a repair system, and prevent the skin from aging in advance.
The fullerene can be well compatible with free radicals, achieves strong oxidation resistance (the oxidation resistance is 172 times of that of vitamin C), activates skin cells, and has a good effect of preventing skin aging.
Further, the content of each component in the aminobutyric acid skin care product is as follows:
and (2) component A: 7.3-9.3 parts of emulsifier, 0.5-1.5 parts of stearic acid, 1.5-3.5 parts of jojoba esters, 1-3 parts of pentaerythritol tetra (ethyl hexanoate), 0.5-1.5 parts of sodium hyaluronate, 0.2-0.7 part of tocopherol acetate, 0.5-1.5 parts of polymethyl methacrylate and 1-3 parts of isotridecanol isononanoate;
and (B) component: 0.5-1.5 parts of dextrin palmitate, 0.2-0.7 part of silica and 5-7 parts of softening agent;
and (3) component C: 0.1-0.2 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.05-0.15 part of allantoin, 0.1-0.3 part of dipotassium glycyrrhizinate, 0.5-1.5 parts of betaine, 0.2-0.7 part of potassium cetyl phosphate, 3-5 parts of glycerol and 1-3 parts of dipropylene glycol;
and (3) component D: 0.1-0.2 part of triethanolamine;
and (3) component E: 0.1-0.3 part of hydroxyphenyl propionamide benzoic acid, 71-2 parts of palmitoyl tetrapeptide, 0.5-1.5 parts of beer yeast extract, 0.2-0.7 part of cactus stem extract, 0.01-0.05 part of fullerene, 0.01-0.05 part of essence, 2-4 parts of 1, 2-pentanediol and 0.1-0.5 part of caprylyl glycol;
and (3) component F: 0.1-0.5 part of aminobutyric acid;
a component G: 1-2 parts of extract of algae of Rhodophyta.
Furthermore, the content of each component in the aminobutyric acid skin care product is as follows:
and (2) component A: 8.3-9.3 parts of emulsifier, 0.5-1 part of stearic acid, 2-3.5 parts of jojoba esters, 2-3 parts of pentaerythritol tetra (ethyl hexanoate), 1-1.5 parts of sodium hyaluronate, 0.5-0.7 part of tocopherol acetate, 1-1.5 parts of polymethyl methacrylate and 2-3 parts of isotridecanol isononanoate;
and (B) component: 1-1.5 parts of dextrin palmitate, 0.5-0.7 part of silica and 6-7 parts of softening agent;
and (3) component C: 0.15-0.2 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.1-0.15 part of allantoin, 0.2-0.3 part of dipotassium glycyrrhizinate, 1-1.5 parts of betaine, 0.5-0.7 part of potassium cetyl phosphate, 4-5 parts of glycerol and 2-3 parts of dipropylene glycol;
and (3) component D: 0.15-0.2 part of triethanolamine;
and (3) component E: 0.2-0.3 part of hydroxyphenyl propionamide benzoic acid, 71.5-2 parts of palmitoyl tetrapeptide, 1-1.5 parts of beer yeast extract, 0.5-0.7 part of cactus stem extract, 0.01-0.05 part of fullerene, 0.01-0.05 part of essence, 3-4 parts of 1, 2-pentanediol and 0.2-0.5 part of caprylyl glycol;
and (3) component F: 0.2-0.5 part of aminobutyric acid;
a component G: 1-1.5 parts of extract of algae of Rhodophyta.
Still further, the above emulsifier comprises: one or more of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, glyceryl stearate/PEG-100 stearate, cetearyl alcohol, beeswax, caprylic triglyceride/capric triglyceride;
wherein, based on the total weight of the aminobutyric acid skin care product, the ratio of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside is as follows: glyceryl stearate/PEG-100 stearate: cetostearyl alcohol: beeswax: the volume ratio of caprylic triglyceride/capric triglyceride is (1-2): (0.5-1.5): (0.5-1.5): (0.5-1): (2-4.3).
Still further, the above jojoba esters include: jojoba esters.
Further, the emollient comprises: one or more of cyclopentadimethylsiloxane and polydimethylsiloxane.
Furthermore, based on the total weight of the aminobutyric acid skin care product, the volume ratio of the cyclopentasiloxane to the polydimethylsiloxane is (2-4): (2-4).
Further, the content of each component in the aminobutyric acid skin care product is as follows:
and (2) component A: 1.5 parts of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, 1 part of glyceryl stearate/PEG-100 stearate, 1 part of cetostearyl alcohol, 0.8 part of beeswax, 1 part of stearic acid, 3 parts of caprylic triglyceride/capric triglyceride, 2.5 parts of jojoba ester, 2 parts of pentaerythritol tetra (ethyl hexanoate), 1 part of sodium hyaluronate, 0.5 part of tocopherol acetate, 1 part of polymethyl methacrylate, and 2 parts of isotridecyl alcohol isononanoate;
and (B) component: 1 part of dextrin palmitate, 0.5 part of silica, 3 parts of cyclopenta dimethyl silicone polymer and 3 parts of dimethyl silicone polymer;
and (3) component C: 0.15 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.15 part of allantoin, 0.2 part of dipotassium glycyrrhizinate, 1 part of betaine, 0.5 part of potassium cetyl phosphate, 4 parts of glycerol and 2 parts of dipropylene glycol;
and (3) component D: 0.15 part of triethanolamine;
and (3) component E: 0.2 part of hydroxyphenyl propionamide benzoic acid, 71.5 parts of palmitoyl tetrapeptide, 1 part of beer yeast extract, 0.5 part of opuntia ficus-indica stem extract, 0.01 part of fullerene, 0.01 part of essence, 3 parts of 1, 2-pentanediol and 0.2 part of caprylyl glycol;
and (3) component F: 0.2 part of aminobutyric acid;
a component G: 1.3 parts of extract of algae of Rhodophyta.
Further, the specific preparation method of the aminobutyric acid skin care product comprises the following steps:
respectively heating the component A, B, C, mixing, cooling, and mixing with the components D, E, F and G to obtain the skin care product containing aminobutyric acid.
The invention has the beneficial effects that:
the invention contains various effective active ingredients such as beer yeast extract, cactus stem extract, rhodophyta extract and the like, and can enhance cell repair and prevent skin aging. Secondly, the fullerene can promote the activation of skin cells and further reduce the aging effect. In addition, the invention also contains various components with moisturizing and anti-inflammatory effects, which can keep the skin moisture and prevent skin inflammation and related problems.
Detailed Description
In order to make the objects, technical solutions and technical effects of the present invention more clear, the present invention will be described in further detail with reference to specific embodiments. It should be understood that the detailed description and specific examples, while indicating the preferred embodiment of the invention, are intended for purposes of illustration only and are not intended to limit the scope of the invention.
The experimental materials and reagents used are, unless otherwise specified, all consumables and reagents which are conventionally available from commercial sources.
The plant extracts used in the present invention are all commercially available:
brewers yeast extract (trade name:
) From Bisheng trade company, Guangzhou city, Opuntia ficus-indica Stem extract (trade name:) from Guangzhou Liao trade company, Rhodophyta algae extract from Guangzhou jin Yuan chemical trade company, Fullerene from Baihabo company, Guangzhou city, and aminobutyric acid (trade name: Gabacare B L98T) from Huaxi Fu Rui biomedical company, Inc.
Example 1 Aminobutanoic acid skin Care product
And (2) component A: 1 part of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, 0.5 part of glyceryl stearate/PEG-100 stearate, 0.5 part of cetearyl alcohol, 1 part of beeswax, 1.5 parts of stearic acid, 2.8 parts of caprylic triglyceride/capric triglyceride, 1.5 parts of jojoba ester, 1 part of pentaerythritol tetra (ethyl hexanoate), 0.5 part of sodium hyaluronate, 0.2 part of tocopherol acetate, 0.5 part of polymethyl methacrylate, and 1 part of isotridecyl alcohol isononanoate;
and (B) component: 0.5 part of dextrin palmitate, 0.2 part of silica, 2 parts of cyclopenta dimethyl silicone polymer and 4 parts of dimethyl silicone polymer by volume;
and (3) component C: 0.1 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.05 part of allantoin, 0.1 part of dipotassium glycyrrhizinate, 0.5 part of betaine, 0.2 part of potassium cetyl phosphate, 3 parts of glycerol and 1 part of dipropylene glycol;
and (3) component D: 0.1 part of triethanolamine;
and (3) component E: 0.1 part of hydroxyphenyl propionamide benzoic acid, 0.71 part of palmitoyl tetrapeptide, 0.5 part of beer yeast extract, 0.2 part of opuntia ficus-indica stem extract, 0.01 part of fullerene, 0.01 part of essence, 2 parts of 1, 2-pentanediol and 0.1 part of caprylyl glycol;
and (3) component F: 0.1 part of aminobutyric acid;
a component G: 1 part of extract of algae of Rhodophyta.
The specific preparation method of the aminobutyric acid skin care product comprises the following steps:
respectively heating the component A, B, C, mixing, cooling, and mixing with the components D, E, F and G to obtain the skin care product containing aminobutyric acid.
EXAMPLE 2 aminobutyric acid skin Care
And (2) component A: 2 parts of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, 1.5 parts of glyceryl stearate/PEG-100 stearate, 1.5 parts of cetearyl alcohol, 0.5 part of beeswax, 0.5 part of stearic acid, 3.3 parts of caprylic triglyceride/capric triglyceride, 3.5 parts of jojoba ester, 3 parts of pentaerythritol tetra (ethyl hexanoate), 1.5 parts of sodium hyaluronate, 0.7 part of tocopherol acetate, 1.5 parts of polymethyl methacrylate, and 3 parts of isotridecyl alcohol isononanoate;
and (B) component: 1.5 parts of dextrin palmitate, 0.7 part of silica, 4 parts of cyclopenta dimethyl silicone polymer and 3 parts of dimethyl silicone polymer by volume;
and (3) component C: 0.2 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.15 part of allantoin, 0.3 part of dipotassium glycyrrhizinate, 1.5 parts of betaine, 0.7 part of potassium cetyl phosphate, 5 parts of glycerol and 3 parts of dipropylene glycol;
and (3) component D: 0.2 part of triethanolamine;
and (3) component E: 0.3 part of hydroxyphenyl propionamide benzoic acid, 72 parts of palmitoyl tetrapeptide, 1.5 parts of beer yeast extract, 0.7 part of opuntia ficus indica stem extract, 0.05 part of fullerene, 0.05 part of essence, 4 parts of 1, 2-pentanediol and 0.5 part of caprylyl glycol;
and (3) component F: 0.5 part of aminobutyric acid;
a component G: 2 parts of extract of algae of Rhodophyta.
An aminobutyric acid skin care product was prepared according to the preparation method of example 1.
Example 3 Aminobutanoic acid skin Care product
And (2) component A: 2 parts of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, 1.5 parts of glyceryl stearate/PEG-100 stearate, 1.5 parts of cetearyl alcohol, 1.5 parts of beeswax, 1.5 parts of stearic acid, 2.3 parts of caprylic triglyceride/capric triglyceride, 3.5 parts of jojoba ester, 2 parts of pentaerythritol tetra (ethyl hexanoate), 1 part of sodium hyaluronate, 0.5 part of tocopherol acetate, 1 part of polymethyl methacrylate, and 2 parts of isotridecyl alcohol isononanoate;
and (B) component: 1 part of dextrin palmitate, 0.5 part of silica, 4 parts of cyclopenta dimethyl silicone polymer and 2 parts of dimethyl silicone polymer by volume;
and (3) component C: 0.15 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.1 part of allantoin, 0.2 part of dipotassium glycyrrhizinate, 1 part of betaine, 0.5 part of potassium cetyl phosphate, 4 parts of glycerol and 2 parts of dipropylene glycol;
and (3) component D: 0.15 part of triethanolamine;
and (3) component E: 0.2 part of hydroxyphenyl propionamide benzoic acid, 71.5 parts of palmitoyl tetrapeptide, 1 part of beer yeast extract, 0.5 part of opuntia ficus-indica stem extract, 0.01 part of fullerene, 0.01 part of essence, 3 parts of 1, 2-pentanediol and 0.2 part of caprylyl glycol;
and (3) component F: 0.2 part of aminobutyric acid;
a component G: 1 part of extract of algae of Rhodophyta.
An aminobutyric acid skin care product was prepared according to the preparation method of example 1.
Example 4 Aminobutanoic acid skin Care products
And (2) component A: 1 part of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, 0.5 part of glyceryl stearate/PEG-100 stearate, 0.5 part of cetostearyl alcohol, 1.5 parts of beeswax, 1.5 parts of stearic acid, 4.3 parts of caprylic triglyceride/capric triglyceride, 3.5 parts of jojoba ester, 2 parts of pentaerythritol tetra (ethyl hexanoate), 1 part of sodium hyaluronate, 0.5 part of tocopherol acetate, 1 part of polymethyl methacrylate, and 2 parts of isotridecyl alcohol isononanoate;
and (B) component: 1 part of dextrin palmitate, 0.5 part of silica, 3 parts of cyclopenta dimethyl silicone polymer and 4 parts of dimethyl silicone polymer by volume;
and (3) component C: 0.15 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.1 part of allantoin, 0.2 part of dipotassium glycyrrhizinate, 1 part of betaine, 0.5 part of potassium cetyl phosphate, 4 parts of glycerol and 2 parts of dipropylene glycol;
and (3) component D: 0.15 part of triethanolamine;
and (3) component E: 0.2 part of hydroxyphenyl propionamide benzoic acid, 71.5 parts of palmitoyl tetrapeptide, 1 part of beer yeast extract, 0.5 part of opuntia ficus-indica stem extract, 0.01 part of fullerene, 0.01 part of essence, 3 parts of 1, 2-pentanediol and 0.2 part of caprylyl glycol;
and (3) component F: 0.2 part of aminobutyric acid;
a component G: 1 part of extract of algae of Rhodophyta.
An aminobutyric acid skin care product was prepared according to the preparation method of example 1.
EXAMPLE 5 aminobutyric acid skin Care
And (2) component A: 1.5 parts of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, 1 part of glyceryl stearate and/or PEG-100 stearate, 1 part of cetostearyl alcohol, 0.8 part of beeswax, 1 part of stearic acid, 3 parts of caprylic triglyceride and/or capric triglyceride, 2.5 parts of jojoba ester, 2 parts of pentaerythritol tetra (ethyl hexanoate), 1 part of sodium hyaluronate, 0.5 part of tocopherol acetate, 1 part of polymethyl methacrylate, 2 parts of isotridecyl alcohol isononanoate;
and (B) component: 1 part of dextrin palmitate, 0.5 part of silica, 3 parts of cyclopenta dimethyl silicone polymer and 3 parts of dimethyl silicone polymer;
and (3) component C: 0.15 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.15 part of allantoin, 0.2 part of dipotassium glycyrrhizinate, 1 part of betaine, 0.5 part of potassium cetyl phosphate, 4 parts of glycerol and 2 parts of dipropylene glycol;
and (3) component D: 0.15 part of triethanolamine;
and (3) component E: 0.2 part of hydroxyphenyl propionamide benzoic acid, 71.5 parts of palmitoyl tetrapeptide, 1 part of beer yeast extract, 0.5 part of opuntia ficus-indica stem extract, 0.01 part of fullerene, 0.01 part of essence, 3 parts of 1, 2-pentanediol and 0.2 part of caprylyl glycol;
and (3) component F: 0.2 part of aminobutyric acid;
a component G: 1.3 parts of extract of algae of Rhodophyta.
An aminobutyric acid skin care product was prepared according to the preparation method of example 1.
Comparative example 1 Fullerene-deficient skin care product
And (2) component A: 1.5 parts of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, 1 part of glyceryl stearate and/or PEG-100 stearate, 1 part of cetostearyl alcohol, 0.8 part of beeswax, 1 part of stearic acid, 3 parts of caprylic triglyceride and/or capric triglyceride, 2.5 parts of jojoba ester, 2 parts of pentaerythritol tetra (ethyl hexanoate), 1 part of sodium hyaluronate, 0.5 part of tocopherol acetate, 1 part of polymethyl methacrylate, 2 parts of isotridecyl alcohol isononanoate;
and (B) component: 1 part of dextrin palmitate, 0.5 part of silica, 3 parts of cyclopenta dimethyl silicone polymer and 3 parts of dimethyl silicone polymer;
and (3) component C: 0.15 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.15 part of allantoin, 0.2 part of dipotassium glycyrrhizinate, 1 part of betaine, 0.5 part of potassium cetyl phosphate, 4 parts of glycerol and 2 parts of dipropylene glycol;
and (3) component D: 0.15 part of triethanolamine;
and (3) component E: 0.2 part of hydroxyphenyl propionamide benzoic acid, 71.5 parts of palmitoyl tetrapeptide, 1 part of beer yeast extract, 0.5 part of opuntia ficus-indica stem extract, 0.01 part of fullerene, 0.01 part of essence, 3 parts of 1, 2-pentanediol and 0.2 part of caprylyl glycol;
and (3) component F: 0.2 part of aminobutyric acid;
a component G: 1.3 parts of extract of algae of Rhodophyta.
An aminobutyric acid skin care product was prepared according to the preparation method of example 1.
Comparative example 2 skin care product lacking aminobutyric acid
And (2) component A: 1.5 parts of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, 1 part of glyceryl stearate and/or PEG-100 stearate, 1 part of cetostearyl alcohol, 0.8 part of beeswax, 1 part of stearic acid, 3 parts of caprylic triglyceride and/or capric triglyceride, 2.5 parts of jojoba ester, 2 parts of pentaerythritol tetra (ethyl hexanoate), 1 part of sodium hyaluronate, 0.5 part of tocopherol acetate, 1 part of polymethyl methacrylate, 2 parts of isotridecyl alcohol isononanoate;
and (B) component: 1 part of dextrin palmitate, 0.5 part of silica, 3 parts of cyclopenta dimethyl silicone polymer and 3 parts of dimethyl silicone polymer;
and (3) component C: 0.15 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.15 part of allantoin, 0.2 part of dipotassium glycyrrhizinate, 1 part of betaine, 0.5 part of potassium cetyl phosphate, 4 parts of glycerol and 2 parts of dipropylene glycol;
and (3) component D: 0.15 part of triethanolamine;
and (3) component E: 0.2 part of hydroxyphenyl propionamide benzoic acid, 71.5 parts of palmitoyl tetrapeptide, 1 part of beer yeast extract, 0.5 part of opuntia ficus-indica stem extract, 0.01 part of fullerene, 0.01 part of essence, 3 parts of 1, 2-pentanediol and 0.2 part of caprylyl glycol;
and (3) component F: replacing 0.2 part of aminobutyric acid with water;
a component G: 1.3 parts of extract of algae of Rhodophyta.
An aminobutyric acid skin care product was prepared according to the preparation method of example 1.
Comparative example 3 skin care product lacking Saccharomyces cerevisiae extract
And (2) component A: 1.5 parts of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, 1 part of glyceryl stearate and/or PEG-100 stearate, 1 part of cetostearyl alcohol, 0.8 part of beeswax, 1 part of stearic acid, 3 parts of caprylic triglyceride and/or capric triglyceride, 2.5 parts of jojoba ester, 2 parts of pentaerythritol tetra (ethyl hexanoate), 1 part of sodium hyaluronate, 0.5 part of tocopherol acetate, 1 part of polymethyl methacrylate, 2 parts of isotridecyl alcohol isononanoate;
and (B) component: 1 part of dextrin palmitate, 0.5 part of silica, 3 parts of cyclopenta dimethyl silicone polymer and 3 parts of dimethyl silicone polymer;
and (3) component C: 0.15 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.15 part of allantoin, 0.2 part of dipotassium glycyrrhizinate, 1 part of betaine, 0.5 part of potassium cetyl phosphate, 4 parts of glycerol and 2 parts of dipropylene glycol;
and (3) component D: 0.15 part of triethanolamine;
and (3) component E: 0.2 part of hydroxyphenyl propionamide benzoic acid, 71.5 parts of palmitoyl tetrapeptide, 0.5 part of cactus stem extract, 0.01 part of fullerene, 0.01 part of essence, 3 parts of 1, 2-pentanediol and 0.2 part of caprylyl glycol;
and (3) component F: 0.2 part of aminobutyric acid;
a component G: 1.3 parts of extract of algae of Rhodophyta.
An aminobutyric acid skin care product was prepared according to the preparation method of example 1.
Comparative example 4 skin care product lacking extract of Haematococcus
And (2) component A: 1.5 parts of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, 1 part of glyceryl stearate and/or PEG-100 stearate, 1 part of cetostearyl alcohol, 0.8 part of beeswax, 1 part of stearic acid, 3 parts of caprylic triglyceride and/or capric triglyceride, 2.5 parts of jojoba ester, 2 parts of pentaerythritol tetra (ethyl hexanoate), 1 part of sodium hyaluronate, 0.5 part of tocopherol acetate, 1 part of polymethyl methacrylate, 2 parts of isotridecyl alcohol isononanoate;
and (B) component: 1 part of dextrin palmitate, 0.5 part of silica, 3 parts of cyclopenta dimethyl silicone polymer and 3 parts of dimethyl silicone polymer;
and (3) component C: 0.15 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.15 part of allantoin, 0.2 part of dipotassium glycyrrhizinate, 1 part of betaine, 0.5 part of potassium cetyl phosphate, 4 parts of glycerol and 2 parts of dipropylene glycol;
and (3) component D: 0.15 part of triethanolamine;
and (3) component E: 0.2 part of hydroxyphenyl propionamide benzoic acid, 71.5 parts of palmitoyl tetrapeptide, 1 part of beer yeast extract, 0.5 part of opuntia ficus-indica stem extract, 0.01 part of fullerene, 0.01 part of essence, 3 parts of 1, 2-pentanediol and 0.2 part of caprylyl glycol;
and (3) component F: 0.2 part of aminobutyric acid;
a component G: 1.3 parts of extract of alga belonging to the phylum Rhodophyta is replaced by water.
An aminobutyric acid skin care product was prepared according to the preparation method of example 1.
Comparative example 5 skin care product lacking opuntia ficus indica stem extract
And (2) component A: 1.5 parts of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, 1 part of glyceryl stearate and/or PEG-100 stearate, 1 part of cetostearyl alcohol, 0.8 part of beeswax, 1 part of stearic acid, 3 parts of caprylic triglyceride and/or capric triglyceride, 2.5 parts of jojoba ester, 2 parts of pentaerythritol tetra (ethyl hexanoate), 1 part of sodium hyaluronate, 0.5 part of tocopherol acetate, 1 part of polymethyl methacrylate, 2 parts of isotridecyl alcohol isononanoate;
and (B) component: 1 part of dextrin palmitate, 0.5 part of silica, 3 parts of cyclopenta dimethyl silicone polymer and 3 parts of dimethyl silicone polymer;
and (3) component C: 0.15 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.15 part of allantoin, 0.2 part of dipotassium glycyrrhizinate, 1 part of betaine, 0.5 part of potassium cetyl phosphate, 4 parts of glycerol and 2 parts of dipropylene glycol;
and (3) component D: 0.15 part of triethanolamine;
and (3) component E: 0.2 part of hydroxyphenyl propionamide benzoic acid, 71.5 parts of palmitoyl tetrapeptide, 1 part of beer yeast extract, 0.01 part of fullerene, 0.01 part of essence, 3 parts of 1, 2-pentanediol and 0.2 part of caprylyl glycol;
and (3) component F: 0.2 part of aminobutyric acid;
a component G: 1.3 parts of extract of algae of Rhodophyta.
An aminobutyric acid skin care product was prepared according to the preparation method of example 1.
Comparative example 6 skin care product lacking Saccharomyces cerevisiae extract, Opuntia ficus indica Stem extract, Euglena extract, aminobutyric acid and Fullerene
And (2) component A: 1.5 parts of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, 1 part of glyceryl stearate and/or PEG-100 stearate, 1 part of cetostearyl alcohol, 0.8 part of beeswax, 1 part of stearic acid, 3 parts of caprylic triglyceride and/or capric triglyceride, 2.5 parts of jojoba ester, 2 parts of pentaerythritol tetra (ethyl hexanoate), 1 part of sodium hyaluronate, 0.5 part of tocopherol acetate, 1 part of polymethyl methacrylate, 2 parts of isotridecyl alcohol isononanoate;
and (B) component: 1 part of dextrin palmitate, 0.5 part of silica, 3 parts of cyclopenta dimethyl silicone polymer and 3 parts of dimethyl silicone polymer;
and (3) component C: 0.15 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.15 part of allantoin, 0.2 part of dipotassium glycyrrhizinate, 1 part of betaine, 0.5 part of potassium cetyl phosphate, 4 parts of glycerol and 2 parts of dipropylene glycol;
and (3) component D: 0.15 part of triethanolamine;
and (3) component E: 0.2 part of hydroxyphenylpropionamide benzoic acid, 71.5 parts of palmitoyl tetrapeptide, 0.01 part of essence, 3 parts of 1, 2-pentanediol and 0.2 part of caprylyl glycol;
and (3) component F: replacing 0.2 part of aminobutyric acid with water;
a component G: 1.3 parts of extract of alga belonging to the phylum Rhodophyta is replaced by water.
An aminobutyric acid skin care product was prepared according to the preparation method of example 1.
The effects of the above examples and comparative examples were further examined.
Antioxidant Activity test
The antioxidant activity (AOA) of inventive examples 1-5 and comparative examples 1-6 was determined, the AOA representing the coulomb consumption per 100g of the analyzed material, as shown in table 1:
TABLE 1
Table 1 shows that the antioxidant activity of examples 1-5 according to the composition of the present invention is significantly higher than that of the comparative examples, indicating that the brewers' yeast extract, opuntia ficus-indica stalk extract, gloeophyta extract, aminobutyric acid and fullerene of the present invention all play a good antioxidant role.
Skin color testing
Skin complexion L values were determined and their effect on skin radiance was evaluated by measuring the change in skin L values before and after use of the product using a skin color tester Colorimeter C L400 manufactured by Courage Khazaka (CK) germany, and three groups of subjects having the same mean value of the initial L values were tested, 10 persons per group, for a period of 4 weeks, and the results were averaged as shown in table 2:
TABLE 2
Table 2 shows that examples 1-5, which were composed of the ingredients according to the present invention, had significantly stronger effects on skin lightening than the comparative examples, indicating that the brewers yeast extract, opuntia ficus-indica stalk extract, gloeophyta extract, aminobutyric acid and fullerene of the present invention all provided excellent improvement in skin lightening in subjects.
Skin hydration test
Skin hydration was measured to have the same starting mean for three groups of 10 subjects over a four week period, and the results averaged, as in table 3:
TABLE 3
Table 3 shows that examples 1-5, which are composed of the ingredients according to the present invention, have significantly stronger effects on the skin water-retention ability than the comparative examples, indicating that the brewers' yeast extract, opuntia ficus indica stem extract, gloeophyta extract, aminobutyric acid and fullerene of the present invention are capable of significantly indicating the skin hydration level of the subject.
The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.
Claims (9)
1. The skin care product containing aminobutyric acid is characterized by comprising the following components:
and (2) component A: emulsifier, stearic acid, jojoba esters, pentaerythritol tetra (ethyl hexanoate) ester, sodium hyaluronate, tocopherol acetate, polymethyl methacrylate, isotridecanol isononanoate;
and (B) component: dextrin palmitate, silica, emollients;
and (3) component C: acrylic acid/C10-30 alkanol acrylate crosspolymer, allantoin, dipotassium glycyrrhizinate, betaine, potassium cetyl phosphate, glycerol, dipropylene glycol;
and (3) component D: triethanolamine;
and (3) component E: hydroxyphenyl propionamide benzoic acid, palmitoyl tetrapeptide-7, brewer's yeast extract, cactus stem extract, fullerene, essence, 1, 2-pentanediol, and caprylyl glycol;
and (3) component F: aminobutyric acid;
a component G: extract of Haematococcus sp.
2. The aminobutyric acid skin care product according to claim 1, wherein the content of each component in the aminobutyric acid skin care product is as follows:
and (2) component A: 7.3-9.3 parts of emulsifier, 0.5-1.5 parts of stearic acid, 1.5-3.5 parts of jojoba esters, 1-3 parts of pentaerythritol tetra (ethyl hexanoate), 0.5-1.5 parts of sodium hyaluronate, 0.2-0.7 part of tocopherol acetate, 0.5-1.5 parts of polymethyl methacrylate and 1-3 parts of isotridecanol isononanoate;
and (B) component: 0.5-1.5 parts of dextrin palmitate, 0.2-0.7 part of silica and 5-7 parts of softening agent;
and (3) component C: 0.1-0.2 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.05-0.15 part of allantoin, 0.1-0.3 part of dipotassium glycyrrhizinate, 0.5-1.5 parts of betaine, 0.2-0.7 part of potassium cetyl phosphate, 3-5 parts of glycerol and 1-3 parts of dipropylene glycol;
and (3) component D: 0.1-0.2 part of triethanolamine;
and (3) component E: 0.1-0.3 part of hydroxyphenyl propionamide benzoic acid, 71-2 parts of palmitoyl tetrapeptide, 0.5-1.5 parts of beer yeast extract, 0.2-0.7 part of cactus stem extract, 0.01-0.05 part of fullerene, 0.01-0.05 part of essence, 2-4 parts of 1, 2-pentanediol and 0.1-0.5 part of caprylyl glycol;
and (3) component F: 0.1-0.5 part of aminobutyric acid;
a component G: 1-2 parts of extract of algae of Rhodophyta.
3. The aminobutyric acid skin care product according to claim 2, wherein the content of each component in the aminobutyric acid skin care product is as follows:
and (2) component A: 8.3-9.3 parts of emulsifier, 0.5-1 part of stearic acid, 2-3.5 parts of jojoba esters, 2-3 parts of pentaerythritol tetra (ethyl hexanoate), 1-1.5 parts of sodium hyaluronate, 0.5-0.7 part of tocopherol acetate, 1-1.5 parts of polymethyl methacrylate and 2-3 parts of isotridecanol isononanoate;
and (B) component: 1-1.5 parts of dextrin palmitate, 0.5-0.7 part of silica and 6-7 parts of softening agent;
and (3) component C: 0.15-0.2 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.1-0.15 part of allantoin, 0.2-0.3 part of dipotassium glycyrrhizinate, 1-1.5 parts of betaine, 0.5-0.7 part of potassium cetyl phosphate, 4-5 parts of glycerol and 2-3 parts of dipropylene glycol;
and (3) component D: 0.15-0.2 part of triethanolamine;
and (3) component E: 0.2-0.3 part of hydroxyphenyl propionamide benzoic acid, 71.5-2 parts of palmitoyl tetrapeptide, 1-1.5 parts of beer yeast extract, 0.5-0.7 part of cactus stem extract, 0.01-0.05 part of fullerene, 0.01-0.05 part of essence, 3-4 parts of 1, 2-pentanediol and 0.2-0.5 part of caprylyl glycol;
and (3) component F: 0.2-0.5 part of aminobutyric acid;
a component G: 1-1.5 parts of extract of algae of Rhodophyta.
4. An aminobutyric acid skin care product according to any one of claims 1 to 3, wherein said emulsifier comprises: one or more of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, glyceryl stearate/PEG-100 stearate, cetearyl alcohol, beeswax, caprylic triglyceride/capric triglyceride;
wherein arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside: glyceryl stearate/PEG-100 stearate: cetostearyl alcohol: beeswax: the volume ratio of caprylic triglyceride/capric triglyceride is (1-2): (0.5-1.5): (0.5-1.5): (0.5-1): (2-4.3).
5. An aminobutyric acid skin care product according to any one of claims 1 to 3, wherein said jojoba esters comprise: jojoba esters.
6. An aminobutyric acid skin care product according to any one of claims 1 to 3, wherein said emollient comprises: one or more of cyclopentadimethylsiloxane and polydimethylsiloxane.
7. The aminobutyric acid skin care product of claim 6, wherein the volume ratio of cyclopentadimethylsiloxane to polydimethylsiloxane is (2-4): (2-4).
8. The aminobutyric acid skin care product according to claim 1, wherein the content of each component in the aminobutyric acid skin care product is as follows:
and (2) component A: 1.5 parts of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, 1 part of glyceryl stearate/PEG-100 stearate, 1 part of cetostearyl alcohol, 0.8 part of beeswax, 1 part of stearic acid, 3 parts of caprylic triglyceride/capric triglyceride, 2.5 parts of jojoba ester, 2 parts of pentaerythritol tetra (ethyl hexanoate), 1 part of sodium hyaluronate, 0.5 part of tocopherol acetate, 1 part of polymethyl methacrylate, and 2 parts of isotridecyl alcohol isononanoate;
and (B) component: 1 part of dextrin palmitate, 0.5 part of silica, 3 parts of cyclopenta dimethyl silicone polymer and 3 parts of dimethyl silicone polymer;
and (3) component C: 0.15 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.15 part of allantoin, 0.2 part of dipotassium glycyrrhizinate, 1 part of betaine, 0.5 part of potassium cetyl phosphate, 4 parts of glycerol and 2 parts of dipropylene glycol;
and (3) component D: 0.15 part of triethanolamine;
and (3) component E: 0.2 part of hydroxyphenyl propionamide benzoic acid, 71.5 parts of palmitoyl tetrapeptide, 1 part of beer yeast extract, 0.5 part of opuntia ficus-indica stem extract, 0.01 part of fullerene, 0.01 part of essence, 3 parts of 1, 2-pentanediol and 0.2 part of caprylyl glycol;
and (3) component F: 0.2 part of aminobutyric acid;
a component G: 1.3 parts of extract of algae of Rhodophyta.
9. The aminobutyric acid skin care product according to claim 1, wherein the specific preparation method of the aminobutyric acid skin care product comprises the following steps:
respectively heating the component A, B, C, mixing, cooling, and mixing with the components D, E, F and G to obtain the skin care product containing aminobutyric acid.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115531262A (en) * | 2022-09-02 | 2022-12-30 | 花安堂生物科技集团有限公司 | Method for improving stability of oil-soluble ascorbic acid derivative and application thereof |
-
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Non-Patent Citations (1)
| Title |
|---|
| 安婕妤化妆品科技股份有限公司: "安吉希可儿 生命知焕妩痕耀眼霜", 《国产非特殊用途化妆品备案信息服务平台》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115531262A (en) * | 2022-09-02 | 2022-12-30 | 花安堂生物科技集团有限公司 | Method for improving stability of oil-soluble ascorbic acid derivative and application thereof |
| CN115531262B (en) * | 2022-09-02 | 2024-04-05 | 花安堂生物科技集团有限公司 | Method for improving stability of oil-soluble ascorbic acid derivative and application thereof |
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