CN111450197A - Formula of pure traditional Chinese medicine external disinfectant containing ethanol - Google Patents

Abstract

The invention relates to a formula of a pure traditional Chinese medicine external disinfectant containing ethanol, which is developed according to the defects of the existing common disinfection measures and the hidden health trouble of human bodies caused by long-term use, and can be directly used for disinfecting skin surfaces and tableware. The Chinese herbal medicines related in the formula have the pharmacological effects of freeing lung, regulating qi, eliminating phlegm, relieving and calming heart, preventing cold, protecting skin and resisting oxidation and the like, can be used for protecting various pathogenic bacteria and viruses, and is particularly suitable for disinfecting novel coronavirus spread infection. The disinfectant involved in the invention has simple and easy preparation process and obvious effect, and can be used as a self-made sterilizing disinfectant necessary for daily work and life.

Description

Formula of pure traditional Chinese medicine external disinfectant containing ethanol

Technical Field

The invention relates to an external disinfectant formula, in particular to a pure traditional Chinese medicine external disinfectant formula containing ethanol.

Technical Field

There are three main ways of spreading novel coronaviruses: the droplet transmission, direct transmission and contact transmission, and daily disinfection become necessary virus transmission infection prevention measures in work and life. The protection measures for daily virus transmission and infection need to be the first factor of ensuring that safety threat and health hidden danger cannot be caused to human bodies, and the disinfection can be conveniently carried out at any time and any place in daily work and life. In view of the nature of viral transmission infections, comprehensive viral protection is not only the disinfection of items used in daily life, but also the disinfection of skin surfaces, especially hand and facial skin. The following disinfection methods are commonly used at present:

1. alcohol disinfection: the alcohol is applied to the surface of an object to effectively inactivate viruses. The disadvantage is that the amount used must be strictly controlled because the alcohol concentration in a windless room to some extent is liable to cause combustion explosion. Moreover, the direct application of alcohol on the skin surface can cause irritation and damage to the skin, so that the alcohol is not suitable for daily sterilization and disinfection of the skin surface.

2.84 disinfectant solution Disinfection 84 disinfectant solution is applied on the surface of an object to effectively kill virus, but during epidemic situations, because people who frequently use the disinfectant solution and frequently contact the disinfectant solution with hands can sweat a lot of hands, nails are thin, hairs fall off and have sensitization, free chlorine released in the using process of the disinfectant solution can cause poisoning, chlorine is a toxic gas, the chlorine mainly invades into the human body through respiratory tracts and is dissolved in water contained in mucous membranes to cause dyspnea, so the obvious symptom of chlorine poisoning is severe cough, pulmonary edema can occur when the symptom is serious, the chlorine can cause death due to dyspnea, the chlorine entering the human body from esophagus can cause nausea, vomiting, chest pain and diarrhea, the maximum allowable chlorine content in 1L air is 0.001mg, and the amount exceeding the chlorine can cause poisoning of the human body, and the using amount and the disinfection rate are limited.

3. Ultraviolet and ozone disinfection measures: the requirement on indoor temperature and humidity is required, and the disinfection direction needs to be determined manually and directionally; ultraviolet rays can only disinfect within a fixed, indoor, irradiatable range and cannot directly disinfect the human body.

The alcohol can be disinfected because the alcohol can absorb the water of the virus protein, so that the virus protein is dehydrated, denatured and solidified, thereby achieving the aim of killing viruses. In addition, alcohol is a good organic solvent and has good penetrability, and the effect is caused because the ethanol molecules in the alcohol can easily enter the tissue cells of the medicinal materials. Ethanol can dissolve many water-insoluble active ingredients of drugs, such as flavonoid, triterpenes, steroids, tannin, volatile oil and fatty acid type active ingredients of drugs, which are insoluble in water but soluble in ethanol. Most of the volatile oil extracted from the Chinese herbal medicines has the functions of sweating, regulating qi, relieving pain, inhibiting bacteria, correcting flavor and the like. Modern pharmaceutical research shows that the volatile oil has small molecular weight, strong lipid solubility, high bioavailability, rapid absorption and action, and is easy to penetrate in vivo biological membrane, and is consistent with the theory of traditional Chinese medicine. Therefore, the alcohol containing ethanol and the pure grain brewed white spirit have the functions of virus inactivation and medicine active ingredient dissolution and can be used as base liquid of the disinfectant.

The new coronavirus enters the respiratory system from nasal cavity or oral cavity of human body after infection, and finally invades lung. After the patient is infected with virus, fever, hypodynamia, dry cough and dyspnea gradually occur. The severe symptoms are: dyspnea or hypoxemia, acute respiratory distress syndrome. The degree and duration of the infection reaction are different according to the constitution difference of an infected person, so that the immunity of the body can be maintained against the virus propagation infection deterioration by adding the medical effect of resisting the virus infection reaction on the basis of daily disinfection and protection measures for people with weak immunity or basic diseases of cardiopulmonary dysfunction. Therefore, the respiratory system is ensured to function normally when the human body is enhanced in the virus resistance. Traditional Chinese medicines with the effects of ventilating the lung, regulating qi, reducing phlegm, increasing blood oxygen content, resisting viruses and the like are added into the disinfectant, so that the disinfectant can sterilize and disinfect in daily work and life, and meanwhile, the immunity of a respiratory system is enhanced, and the disinfectant can play a role in effectively resisting virus spread infection.

Disclosure of Invention

The invention relates to a strong-effect sterilization and antivirus external disinfectant formula containing ethanol and having the effects of resisting virus, preventing virus propagation, protecting skin, resisting oxidation, enhancing the resistance of a respiratory system and the like, and the disinfectant formula can be used for disinfecting the surfaces of objects, the surfaces of skins and air in daily work and life. In the using process, the volatile ethanol molecules carry the effective components of the medicine to enter a respiratory system through skin tissues of a human body or mouth and nose respiration and participate in the internal circulation of the human body, the ethanol can play a role in dehydrating virus proteins, and the effective components of the medicine can play a role in enhancing immune protection and resisting virus propagation infection. The medical science proves that: the speed of the nasal mucosa of the human body for absorbing the medicine is very fast, and the medicine can directly enter blood, and the efficiency of the medicine is comparable to that of transfusion. The nasal cavity absorption metabolism is different from other parts of the human body, so that the effective ingredients of the medicine can be fully utilized. The research shows that the volatile oil contained in the traditional Chinese medicine has the function of promoting the skin absorption, and the efficiency of the medicine is the penetration-promoting medicine with the same efficacy. The final product of the invention can be used for daily protection of various pathogenic viruses, and is particularly suitable for protection of novel coronavirus, SARS virus and influenza virus. The formula of the invention comprises the following raw materials in percentage by weight: 15-25% of rhizoma atractylodis, 10-25% of pogostemon cablin, 10-25% of orange peel, 5-15% of platycodon grandiflorum, 105-15% of herba eupatorii, 10-25% of lavender, 5-15% of lemon grass and alcohol with the content of 75-95%

As a preferable scheme, the alcohol used as the organic solvent can be replaced by 53-65-degree pure grain brewed white spirit brewed by pure grain.

The functions and effects of the components in the formula are as follows:

rhizoma atractylodis: pungent and bitter with warm nature. Meridian tropism includes spleen, stomach and liver meridians. Has the effects of eliminating dampness, strengthening spleen, dispelling pathogenic wind, dispelling cold, and improving eyesight. The traditional Chinese medicine composition is mainly used for treating damp obstruction of middle energizer, abdominal distension, diarrhea, edema, beriberi flaccidity cramped, rheumatism and arthralgia, wind-cold type common cold, night blindness, dim eyesight and unsmooth eyes. As early as in the Han dynasty, Zhang Zhongjing says that rhizoma Atractylodis can avoid all bad breath, and Ming Dynasty Li Shizhen also records that rhizoma Atractylodis can remove bad breath, diseases and senile denier, and tends to burn rhizoma Atractylodis to avoid pathogenic qi when entering home, so that the disease of epidemic is used more. The record of Zhang shan Lei (materia Medica) in recent times: cang Zhu is fragrant and can avoid foul smell and surpass the qi of four seasons, so it is used for epidemic diseases. Most effectively removing foul and foul smell. In the area of haze, it is advisable to burn the material in a long-term open room and then live in the house. The rhizoma atractylodis plays a role in sterilizing and inactivating viruses in the invention, and can effectively invigorate the spleen and eliminate dampness by being used with the patchouli and the eupatorium.

And (3) jojoba leaf: nature and taste: pungent in flavor and slightly warm in nature. Meridian tropism: enter lung, spleen and stomach meridians. Has effects in clearing away summer-heat, regulating the middle warmer, relieving vomit, promoting qi circulation, eliminating dampness, relieving swelling, eliminating jaundice, regulating the five internal organs, invigorating spleen, and stimulating appetite; can be used for treating summer heat and dampness, fullness and oppression in chest and abdomen, emesis, diarrhea, abdominal pain, common cold with dampness, typhoid fever, headache, aversion to cold, fever, cough, heart and abdomen psychroalgia, nausea, vomiting, qi diarrhea, cholera, asthenia of viscera, general asthenia of body, halitosis, and oral ulcer.

1. Promoting digestion

The volatile oil in herba Agastaches has effects of stimulating gastric mucosa, promoting gastric secretion, and promoting digestion.

2. Antiviral agent

The flavonoids in herba Agastaches have antiviral effect, and the components separated from herba Agastaches can inhibit growth and reproduction of virus as pathogen in digestive tract and upper respiratory tract.

The invention can treat diarrhea caused by virus infection to intestines and stomach, and can inhibit the growth and reproduction of virus in respiratory tract and digestive tract. The patchouli has the antiviral effect in the invention, promotes appetite and enhances the resistance of human body.

Orange peel: pungent in flavor and warm in nature, enter spleen and lung meridians. The functional indications are as follows: regulate qi, regulate middle energizer, dry dampness and resolve phlegm. It is indicated for abdominal distention, anorexia, emesis, cough and profuse sputum. Also has effect in removing toxic substances from fish and crab. Tangerine peel, pericarpium Citri Reticulatae can purge dryness by bitter flavor, pungent flavor can disperse warm, tonify energy, resolve phlegm to treat cough, regulate qi and regulate middle energizer, regulate spleen and fast diaphragm, treat stranguria with five types of wind, treat alcohol diseases by the action of all herbs, regulate qi and dry dampness, tonify by tonics, purge by purgative herbs, ascend by ascending by descending by mother of original qi, and control qi by lung by descending by mother of original qi, so Tangerine peel is a herb of qi division of two meridians, and tonify and descend by matching

① Benjing, for governing heat in chest and abdomen, adverse qi, diuresis inducing food, deodorizing after long-term administration and descending qi "

② Biyu (miscellaneous records) for stopping vomiting and cough, removing heat from bladder, stopping water, and eliminating Wulin, promoting urination, governing spleen failing to eliminate food, flushing chest with qi, vomiting cholera, stopping diarrhea, and removing cun-Bai.

③ treatingIn the treatingIng Qi between chest and diaphragm, whetting appetite, promoting dysentery, eliminating phlegm and saliva, treating cough due to excessive Qi "

④ Ben Cao Shi Yi (materia Medica of removing qi and regulating middle warmer) "

⑤ Rihuazi Bencao (Rihuazi Bencao): Xuan Xiaotan Zhisuo, Xiaozhuang Xuan (Xuan) "

⑥ inspiring medicine, namely removing cold evil in chest, breaking stagnant qi and benefiting spleen and stomach "

⑦ compendium for treating vomit, regurgitation, gastric upset, watery vomit, phlegm, malaria , large intestine obstruction, mastitis of women, and fish smell "

⑧ diet spectra for treating fish, crab toxin, hiccup, fullness, infantile malnutrition, dysentery, constipation, and tinea pedis "

The formula of the invention has the functions of regulating qi and freeing lung, and can achieve the effect of assisting the recovery of lung function. The orange peel contains a large amount of vitamin C, has an antioxidation effect, and can resist the damage of oxygen radicals to infected organs in the virus reproduction process.

Balloon flower: bitter and pungent in flavor and mild in nature. It enters lung meridian. Has effects in dispersing lung qi, relieving sore throat, eliminating phlegm, and expelling pus. The main treatment is as follows: cough with profuse sputum, chest distress and poor smoothness. It is indicated for cold or heat because it is pungent, bitter and purgative, dispersing lung qi and dispelling phlegm. The invention plays a role in dispersing lung qi and eliminating phlegm, and effectively assists the virus entering the human body to accelerate the discharge so as to avoid infection.

Lavender: lavender is a well-known plant with the most sedative, soothing and hypnotic effects. It can relieve nervous emotion, calm mind, and calm breath, and has been used for improving sleep of the elderly by extracting volatile oil from Lavender in hospitals abroad. In Xinjiang, many Uygur hospitals also used lavender whole plant preparations to treat neurasthenia and insomnia. Researches show that the lavender has obvious antibacterial effect, and linalool contained in the lavender is an antibacterial main component of the lavender and can inhibit the growth of 17 bacteria (including gram-negative bacteria and gram-positive bacteria) and 10 fungi. The lavender has anti-inflammatory and anti-oxidation effects, and the lavender essential oil is applied to an inflamed affected part, so that the healing speed of the affected part is found to be high, and the swelling is obviously relieved. Meanwhile, experiments also prove that the 50% methanol extract of the lavandula angustifolia can inhibit lipid peroxidation, wherein the phenolic rosmarinic acid is an antioxidant active substance. The lavender plays a role in sterilization and virus resistance in the invention, the fragrance of the lavender can also relieve emotion, and the lavender can play an antioxidant role when being used for skin surface disinfection.

Herba Eupatorii: the efficacy is as follows: fragrant, resolving dampness, activating spleen, stimulating appetite, relieving exterior syndrome and relieving summer-heat. Can be used for treating damp stagnation, gastric fullness, emesis, halitosis, sialorrhea, summer-heat dampness, headache, and chest distress. It is combined with Huo Xiang to reinforce each other and cang Zhu to resolve dampness with mild property but not warm and dry. The bath lotion contains a large amount of volatile oil, nerol acetate and other substances, can effectively inhibit part of typhoid bacillus, staphylococcus aureus, diphtheria bacillus and the like, and can effectively prevent various skin diseases when a user bathes the bath lotion with the eupatorium. Eupatorium fortunei can also treat viral influenza because the volatile oil component is effective in inhibiting influenza virus. The eupatorium has a fragrance similar to orchid, and is recorded in Shen nong Ben Cao Jing: for the fragrant, healthy qi and exuberant healthy qi will remove pathogenic factors and avoid filthy. The eupatorium fortunei has the function of improving the vital qi of a human body to resist exogenous pathogenic factors, can effectively prevent and treat the dampness weight of the spleen and the stomach by being used together with the pogostemon cablin and the rhizoma atractylodis in the formula, and can also effectively inhibit pathogenic bacteria and viruses.

Lemon grass: lemon grass has the functions of invigorating stomach, promoting urination, preventing anemia and moistening skin, and according to the fact that lemon grass is a medicinal plant for treating various diseases in the traditional Indian medical science, the effects and the functions of lemon grass can be seen very much. The smell is fragrant, and the sterilizing and antiviral effects are achieved, so that the tea is popular among doctors from ancient times to present. Can regulate oil secretion, is beneficial to oily skin and hair, and can be added into water to clean skin and promote blood circulation. The lemon grass has good cleaning effect on human skin, can regulate the secretion of body oil of human, is particularly suitable for people with oily skin or oily hair, can reduce the oil secretion of the people, and has the effect of cleaning the skin at concentration. In addition, the lemon grass has strong conditioning effect on human blood circulation and can reduce the occurrence of certain vascular diseases. The lemon grass has the functions of sterilization and antivirus, the faint scent of the lemon grass can promote healthy qi of a human body, and the lemon grass can be sterilized and disinfected on the surface of daily skin to effectively protect the skin from alcohol stimulation.

Alcohol (or pure grain brewed white spirit): alcohol is effective in inactivating viruses because alcohol contained in alcohol plays a role. One person drunk the king sun Simiao pair wine thousands of years ago, and the whole family is not epidemic; one family drink, one free of epidemic. Modern science proves that the ethanol in the alcohol has a volatile property, so that viruses existing in air in a certain range can be inactivated, and the effect of inhibiting epidemic diseases is achieved. Drinking and plague avoidance is the result of human body experiments of Chinese people and inherits the life experience of the population and even forms cultural customs. The liquor is a medicine, is a long name of hundreds of medicines in ancient times, has the effects of warming channels and dispelling cold, and dredging collaterals and activating blood and relieving pain, is also a guiding drug, and can directly reach the focus when the medicine is introduced. In the invention, the alcohol (or the pure grain brewed white spirit) plays a role in sterilization and disinfection, and the effective components in the medicine are completely dissolved out, so that the antivirus and sterilization effects of the medicine are enhanced; also can be used as guiding drug to the required part in human body and promote the absorption of the effective components.

The invention has the following advantages:

1. inherits the traditional alcohol disinfection effect, and increases the traditional Chinese medicine sterilization and disinfection effect on the basis, thereby enhancing the protective measures for preventing germ and virus infection.

2. The effective components in the traditional Chinese medicine have the medical effects of freeing lung, regulating qi-flowing, eliminating phlegm, relieving and calming heart, preventing cold, protecting skin and resisting oxidation and the like, and are more suitable for people with weak immunity or basic diseases with heart and lung dysfunction.

3. Alcohol has very volatile characteristics, so the final product of the present invention can be used to sterilize the corresponding place by direct spraying or painting.

4. The volatile oil component in the traditional Chinese medicine can form a protective film on the surface of the skin, so that the damage of alcohol to the surface of the skin is avoided.

5. The sterilization and disinfection principle of the invention is based on the principle that protein can be denatured and virus propagation can be inhibited, so that the sterilization and disinfection device can play a role in inactivating and killing various viruses and germs, such as: SARS virus, influenza virus, etc.

Example of the implementation

The first embodiment is as follows: the raw materials are proportioned as follows: 20% of rhizoma atractylodis, 15% of pogostemon cablin, 15% of orange peel, 10% of platycodon grandiflorum, 10% of eupatorium, 20% of lavender and 10% of lemon grass are uniformly mixed, and then the weight ratio of the mixture is 1: 1 is soaked in alcohol with the content of 75 percent, and can be used after the active ingredients of the medicine are completely leached. The disinfectant with the concentration can be used for sterilizing and disinfecting the surfaces of daily work and daily necessities or air.

Example two: the raw materials are proportioned as follows: the preparation method comprises the following steps of uniformly mixing 15% of rhizoma atractylodis, 15% of pogostemon cablin, 20% of orange peel, 10% of platycodon grandiflorum, 10% of fortune eupatorium herb, 20% of lavender and 10% of lemon grass, and soaking the mixture in a pure grain brewed white spirit with the content of 53 degrees, wherein the dosage is based on the condition that the medicines are completely soaked in the white spirit and completely submerge in the medicines, and the preparation method can be used after the effective ingredients of the medicines. The disinfectant with the concentration can be used for sterilizing and disinfecting the surface of the skin.

Example three: the raw materials are proportioned as follows: 20% of rhizoma atractylodis, 20% of pogostemon cablin, 10% of orange peel, 15% of platycodon grandiflorum, 10% of herba eupatorii, 10% of lavender and 15% of lemon grass are uniformly mixed and soaked in alcohol with the content of 95%, the dosage is based on that the medicine is completely soaked in the alcohol and completely submerges the medicine, and the medicine can be used after the effective components of the medicine are completely leached. The disinfectant with the concentration can be used for sterilization and disinfection of medical institutions. When in use, the composition can be diluted as required.

Example four: the raw material extracts are prepared according to the following mixture ratio: 20% of rhizoma atractylodis, 20% of patchouli, 10% of orange peel, 15% of platycodon grandiflorum, 10% of fortune eupatorium herb, 10% of lavender and 15% of lemon grass are uniformly mixed, and then the mixture is mixed according to the weight ratio of 1: mixing 80% and 75% alcohol uniformly. The disinfectant with the concentration can be used for sterilizing and disinfecting the surfaces of daily life and work articles.

Claims (3)

1. The invention relates to an external disinfectant formula, in particular to a pure traditional Chinese medicine external disinfectant formula containing ethanol. The formula of the invention comprises the following raw materials in percentage by weight: 15-25% of rhizoma atractylodis, 10-25% of pogostemon cablin, 10-25% of orange peel, 5-15% of platycodon grandiflorum, 105-15% of herba eupatorii, 10-25% of lavender and 5-15% of lemon grass.

2. As set forth in claim 1: the invention relates to an external disinfectant formula, in particular to a pure traditional Chinese medicine external disinfectant formula containing ethanol. The formula using method provided by the invention is characterized in that the traditional Chinese medicinal materials are soaked in alcohol with the content of 75-95% to dissolve out effective components of the medicine, and the Chinese herbal medicine alcohol obtained by the method is suitable for the surfaces of articles in daily work and life, and is particularly suitable for sterilization and disinfection of a novel coronavirus transmission infection response epidemic situation.

3. As set forth in claim 2: the formula using method provided by the invention is that the traditional Chinese medicinal materials are soaked in 75-95% alcohol to dissolve out the effective ingredients of the medicine. The alcohol can be replaced by 53-65-degree pure grain brewed white spirit for skin surface sterilization and disinfection in daily work and life.