CN111419776A - Composition with blackhead removing effect and preparation thereof - Google Patents

Composition with blackhead removing effect and preparation thereof Download PDF

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Publication number
CN111419776A
CN111419776A CN202010282464.1A CN202010282464A CN111419776A CN 111419776 A CN111419776 A CN 111419776A CN 202010282464 A CN202010282464 A CN 202010282464A CN 111419776 A CN111419776 A CN 111419776A
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parts
composition
stirring
water
pentanediol
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CN202010282464.1A
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Chinese (zh)
Inventor
龚道勇
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Guangzhou Soyawa Bio-Technology Co ltd
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Guangzhou Soyawa Bio-Technology Co ltd
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Priority to CN202010282464.1A priority Critical patent/CN111419776A/en
Publication of CN111419776A publication Critical patent/CN111419776A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365Hydroxycarboxylic acids; Ketocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/445Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof aromatic, i.e. the carboxylic acid directly linked to the aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/70Biological properties of the composition as a whole
    • A61K2800/72Hypo-allergenic

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Cosmetics (AREA)

Abstract

The invention belongs to the technical field of cosmetics, and discloses a composition with a blackhead removing effect and a preparation thereof, wherein the composition with the blackhead removing effect comprises the following raw materials: glycolic acid, hydroxyphenylpropionamide benzoic acid, 1, 2-pentanediol, 4-tert-butylcyclohexanol, royal jelly, and Hamamelis virginiana water. The composition is prepared into cosmetic preparation, and can solve the following problems: firstly, removing black quickly and shrinking pores. And (II) the skin is not irritated while the black is removed, and the skin is mild.

Description

Composition with blackhead removing effect and preparation thereof
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to a composition with a blackhead removing effect and a preparation thereof.
Technical Field
Removing blackness refers to removing blackheads on nose and face by chemical, physical, medical, folk methods, etc., so as to achieve the purpose of beautifying. The blackhead is a hardened grease blocking object, mainly a 'plug' sample consisting of sebum, cell debris and bacteria, is formed by blocking the opening of the hair follicle, and gradually blackens the head contacting the air due to the action of dust, dirt and oxidation in the air, so that the blackhead is called as the blackhead which is not elegant.
At present, a lot of cosmetics for removing black are available on the market, but really effective and mild products are rare, and blackheads are the problems which can be faced by everyone.
Disclosure of Invention
In view of the above problems, the present invention provides a composition with blackhead removing effect, which is prepared into a cosmetic preparation and can solve the following problems: firstly, removing black quickly and shrinking pores. And (II) the skin is not irritated while the black is removed, and the skin is mild.
The invention is realized by the following technical scheme:
a composition with blackhead removing effect comprises the following raw materials: glycolic acid, hydroxyphenylpropionamide benzoic acid, 1, 2-pentanediol, 4-tert-butylcyclohexanol, royal jelly, and Hamamelis virginiana water.
The preferred composition comprises the following components in parts by weight: 1-3 parts of glycolic acid, 0.1-2 parts of hydroxyphenylpropionamide benzoic acid, 0.5-3 parts of a mixture of 1, 2-pentanediol and 4-tert-butylcyclohexanol, 0.1-2 parts of royal jelly and 0.5-10 parts of hamamelis water.
The preferred composition comprises the following components in parts by weight: 1.5-3 parts of glycolic acid, 0.2-2 parts of hydroxyphenylpropionamide benzoic acid, 1-3 parts of a mixture of 1, 2-pentanediol and 4-tert-butylcyclohexanol, 0.2-2 parts of royal jelly and 1-10 parts of hamamelis water.
The preferred composition comprises the following components in parts by weight: 2-3 parts of glycolic acid, 0.5-2 parts of hydroxyphenylpropionamide benzoic acid, 1-3 parts of a mixture of 1, 2-pentanediol and 4-tert-butylcyclohexanol, 0.25-2 parts of royal jelly and 3-10 parts of hamamelis water.
The composition is prepared into essence.
The preparation method of the essence comprises the following steps:
step one, cleaning and disinfecting equipment;
step two, firstly adding water into an emulsifying pot, stirring at a medium speed, heating to 90 ℃, keeping the temperature for 30 minutes, cooling to 60 ℃, stopping cooling, then sequentially adding diglycerol, glycerol, 1, 2-hexanediol, caprylyl glycol and hydroxyphenyl propionamide benzoic acid, and stirring to be uniform;
step three, adding 1, 3-propylene glycol and p-hydroxyacetophenone which are separately preheated to 60 ℃ and uniformly dispersed, and cooling after stirring uniformly;
step four, after cooling to 45 ℃, adding water and glycolic acid which are dissolved in advance, and stirring to be uniform;
step five, adding a mixture of pre-dispersed water, C12-13 alkanol polyether-9, 1, 2-pentanediol and 4-tert-butyl cyclohexanol, and stirring uniformly;
adding water and arginine which are dissolved in advance, and stirring the mixture evenly; adding Lac Regis Apis and Hamamelis Virginiana solution, stirring, aging for 3-5 days, and packaging.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the description is intended to be exemplary only, and is not intended to limit the scope of the present invention. Moreover, in the following description, descriptions of well-known structures and techniques are omitted so as to not unnecessarily obscure the concepts of the present invention.
The essence raw materials of the invention can be obtained from the market.
Preparation examples
Example 1
The blackhead removing essence consists of the following components in percentage by weight: 1% of glycolic acid, 0.5% of hydroxyphenylpropionamide benzoic acid, 0.5% of a mixture of 1, 2-pentanediol and 4-tert-butylcyclohexanol, 0.2% of royal jelly, 0.5% of witch hazel water, 5% of diglycerin, 0.4% of hexanediol, 2% of 1, 3-propanediol, 0.1% of octaethylene glycol, 0.2% of p-hydroxyacetophenone, 1% of C12-13-alkanol polyether-9, and the balance of water.
The preparation method comprises the following steps:
step one, cleaning and disinfecting equipment;
step two, firstly adding water into an emulsifying pot, stirring at a medium speed, heating to 90 ℃, keeping the temperature for 30 minutes, cooling to 60 ℃, stopping cooling, then sequentially adding diglycerol, glycerol, 1, 2-hexanediol, caprylyl glycol and hydroxyphenyl propionamide benzoic acid, and stirring to be uniform;
step three, adding 1, 3-propylene glycol and p-hydroxyacetophenone which are separately preheated to 60 ℃ and uniformly dispersed, and cooling after stirring uniformly;
step four, after cooling to 45 ℃, adding water and glycolic acid which are dissolved in advance, and stirring to be uniform;
step five, adding a mixture of pre-dispersed water, C12-13 alkanol polyether-9, 1, 2-pentanediol and 4-tert-butyl cyclohexanol, and stirring uniformly;
adding water and arginine which are dissolved in advance, and stirring the mixture evenly; adding Lac Regis Apis and Hamamelis Virginiana solution, stirring, aging for 4 days, and packaging.
Example 2
The blackhead removing essence consists of the following components in percentage by weight: 2% glycolic acid, 0.75% hydroxyphenylpropionamide benzoic acid, 0.75% of a mixture of 1, 2-pentanediol and 4-tert-butylcyclohexanol, 0.3% royal jelly, 2% witch hazel water, 5% diglycerin, 0.4% hexanediol, 2% 1, 3 propylene glycol, 0.1% caprylyl glycol, 0.2% p-hydroxyacetophenone, 1% C12-13 alkanol polyether-9, and the balance water.
Step one, cleaning and disinfecting equipment;
step two, firstly adding water into an emulsifying pot, stirring at a medium speed, heating to 90 ℃, keeping the temperature for 30 minutes, cooling to 60 ℃, stopping cooling, then sequentially adding diglycerol, glycerol, 1, 2-hexanediol, caprylyl glycol and hydroxyphenyl propionamide benzoic acid, and stirring to be uniform;
step three, adding 1, 3-propylene glycol and p-hydroxyacetophenone which are separately preheated to 60 ℃ and uniformly dispersed, and cooling after stirring uniformly;
step four, after cooling to 45 ℃, adding water and glycolic acid which are dissolved in advance, and stirring to be uniform;
step five, adding a mixture of pre-dispersed water, C12-13 alkanol polyether-9, 1, 2-pentanediol and 4-tert-butyl cyclohexanol, and stirring uniformly;
adding water and arginine which are dissolved in advance, and stirring the mixture evenly; adding Lac Regis Apis and Hamamelis Virginiana solution, stirring, aging for 3-5 days, and packaging.
Example 3
The blackhead removing essence consists of the following components in percentage by weight: 3% of glycolic acid, 1% of hydroxyphenylpropionamide benzoic acid, 1% of a mixture of 1, 2-pentanediol and 4-tert-butylcyclohexanol, 0.5% of royal jelly, 5% of hamamelis water, 5% of diglycerin, 0.4% of hexanediol, 2% of 1, 3-propanediol, 0.1% of octaethylene glycol, 0.2% of p-hydroxyacetophenone, 1% of C12-13 alkanol polyether-9, and the balance of water.
Step one, cleaning and disinfecting equipment;
step two, firstly adding water into an emulsifying pot, stirring at a medium speed, heating to 90 ℃, keeping the temperature for 30 minutes, cooling to 60 ℃, stopping cooling, then sequentially adding diglycerol, glycerol, 1, 2-hexanediol, caprylyl glycol and hydroxyphenyl propionamide benzoic acid, and stirring to be uniform;
step three, adding 1, 3-propylene glycol and p-hydroxyacetophenone which are separately preheated to 60 ℃ and uniformly dispersed, and cooling after stirring uniformly;
step four, after cooling to 45 ℃, adding water and glycolic acid which are dissolved in advance, and stirring to be uniform;
step five, adding a mixture of pre-dispersed water, C12-13 alkanol polyether-9, 1, 2-pentanediol and 4-tert-butyl cyclohexanol, and stirring uniformly;
adding water and arginine which are dissolved in advance, and stirring the mixture evenly; adding Lac Regis Apis and Hamamelis Virginiana solution, stirring, aging for 3-5 days, and packaging.
Comparative example
The blackhead removing essence consists of the following components in percentage by weight:
1% hydroxyphenylpropionamide benzoic acid, 1% a mixture of 1, 2-pentanediol and 4-tert-butylcyclohexanol, 0.5% royal jelly, 5% witch hazel water, 5% diglycerol, 0.4% hexanediol, 2% 1, 3-propanediol, 0.1% octaethylene glycol, 0.2% p-hydroxyacetophenone, 1% C12-13 alkanol polyether-9, and the balance water.
The preparation method comprises the following steps:
step one, cleaning and disinfecting equipment;
step two, firstly adding water into an emulsifying pot, stirring at a medium speed, heating to 90 ℃, keeping the temperature for 30 minutes, cooling to 60 ℃, stopping cooling, then sequentially adding diglycerol, glycerol, 1, 2-hexanediol, caprylyl glycol and hydroxyphenyl propionamide benzoic acid, and stirring to be uniform;
step three, adding 1, 3-propylene glycol and p-hydroxyacetophenone which are separately preheated to 60 ℃ and uniformly dispersed, and cooling after stirring uniformly;
step four, adding a mixture of pre-dispersed water, C12-13 alkanol polyether-9, 1, 2-pentanediol and 4-tert-butyl cyclohexanol at 45 ℃, and stirring uniformly;
step five, adding water and arginine which are dissolved in advance, and stirring the mixture evenly; adding Lac Regis Apis and Hamamelis Virginiana solution, stirring, aging for 3-5 days, and packaging.
Experimental study
The experimental method comprises the following steps: soaking with cosmetic cotton, applying to skin part to be treated with blackhead, taking out dirt with black head membrane or acne needle after 3-5 min, and cleaning with warm water (no use for children under three years old).
The following data analysis was performed for the above four embodiments:
table 1 comparative tests of different essences
Test items Mildness property Sensation of irritation NC value Black removing effect
Example 1 Mild reaction Moderate stimulation 5 The black removing effect is obvious
Example 2 Is milder Slight stimulation 2.5 The black removing effect is obvious
Example 3 Is mild Has no irritation 0.3 Obvious black removing effect
Comparative example Is mild Has no irritation 0.1 The black removing effect is not obvious
And (4) test conclusion: the tests show that the essence has a better black removing effect.

Claims (6)

1. A composition with the function of removing blackheads is characterized in that the composition comprises the following raw materials: glycolic acid, hydroxyphenylpropionamide benzoic acid, 1, 2-pentanediol, 4-tert-butylcyclohexanol, royal jelly, and Hamamelis virginiana water.
2. The composition with the effect of removing blackheads according to claim 1, which comprises the following components in parts by weight: 1-3 parts of glycolic acid, 0.1-2 parts of hydroxyphenylpropionamide benzoic acid, 0.5-3 parts of a mixture of 1, 2-pentanediol and 4-tert-butylcyclohexanol, 0.1-2 parts of royal jelly and 0.5-10 parts of hamamelis water.
3. The composition with the effect of removing blackheads according to claim 1, which comprises the following components in parts by weight: 1.5-3 parts of glycolic acid, 0.2-2 parts of hydroxyphenylpropionamide benzoic acid, 1-3 parts of a mixture of 1, 2-pentanediol and 4-tert-butylcyclohexanol, 0.2-2 parts of royal jelly and 1-10 parts of hamamelis water.
4. The composition with the effect of removing blackheads according to claim 1, which comprises the following components in parts by weight: 2-3 parts of glycolic acid, 0.5-2 parts of hydroxyphenylpropionamide benzoic acid, 1-3 parts of a mixture of 1, 2-pentanediol and 4-tert-butylcyclohexanol, 0.25-2 parts of royal jelly and 3-10 parts of hamamelis water.
5. The composition for removing blackheads according to any one of claims 1 to 4, wherein the composition is prepared as a serum.
6. The composition for removing blackheads according to claim 5, wherein the essence is prepared by the following steps:
step one, cleaning and disinfecting equipment;
step two, firstly adding water into an emulsifying pot, stirring at a medium speed, heating to 90 ℃, keeping the temperature for 30 minutes, cooling to 60 ℃, stopping cooling, then sequentially adding diglycerol, glycerol, 1, 2-hexanediol, caprylyl glycol and hydroxyphenyl propionamide benzoic acid, and stirring to be uniform;
step three, adding 1, 3-propylene glycol and p-hydroxyacetophenone which are separately preheated to 60 ℃ and uniformly dispersed, and cooling after stirring uniformly;
step four, after cooling to 45 ℃, adding water and glycolic acid which are dissolved in advance, and stirring to be uniform;
step five, adding pre-dispersed water, C12-13 alkanol polyether-9, 1, 2-pentanediol and 4-tert-butyl cyclohexanol, and stirring to be uniform;
adding water and arginine which are dissolved in advance, and stirring the mixture evenly; adding Lac Regis Apis and Hamamelis Virginiana solution, stirring, aging for 3-5 days, and packaging.
CN202010282464.1A 2020-04-12 2020-04-12 Composition with blackhead removing effect and preparation thereof Pending CN111419776A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114767587A (en) * 2022-04-10 2022-07-22 广州诗妃生物科技有限公司 Composition for rapidly exporting comedones and preparation method thereof
CN118161412A (en) * 2024-04-08 2024-06-11 广州骏朗生物科技有限公司 Biological sun-screening agent with anti-inflammatory and allergy-relieving substances

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102448450A (en) * 2009-04-09 2012-05-09 西姆莱斯有限公司 Compositions comprising trans-tert-butyl cyclohexanol as skin irritation-reducing agent
CN107456434A (en) * 2017-09-08 2017-12-12 森知(上海)国际贸易有限公司 Compact pore composition and preparation method thereof
CN109106666A (en) * 2018-09-07 2019-01-01 山东恒糅酒业有限公司 Lotion and preparation method thereof that a kind of antiallergic releives composition and antiallergic is releived
CN109172586A (en) * 2018-07-06 2019-01-11 福州百草堂医药科技有限公司 It is a kind of for alleviating the composition of skin irritatin
CN110638742A (en) * 2019-11-15 2020-01-03 广州环亚化妆品科技有限公司 Blackhead guiding composition, convergence relieving composition and blackhead removing composition consisting of blackhead guiding composition and convergence relieving composition

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102448450A (en) * 2009-04-09 2012-05-09 西姆莱斯有限公司 Compositions comprising trans-tert-butyl cyclohexanol as skin irritation-reducing agent
CN107456434A (en) * 2017-09-08 2017-12-12 森知(上海)国际贸易有限公司 Compact pore composition and preparation method thereof
CN109172586A (en) * 2018-07-06 2019-01-11 福州百草堂医药科技有限公司 It is a kind of for alleviating the composition of skin irritatin
CN109106666A (en) * 2018-09-07 2019-01-01 山东恒糅酒业有限公司 Lotion and preparation method thereof that a kind of antiallergic releives composition and antiallergic is releived
CN110638742A (en) * 2019-11-15 2020-01-03 广州环亚化妆品科技有限公司 Blackhead guiding composition, convergence relieving composition and blackhead removing composition consisting of blackhead guiding composition and convergence relieving composition

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114767587A (en) * 2022-04-10 2022-07-22 广州诗妃生物科技有限公司 Composition for rapidly exporting comedones and preparation method thereof
CN114767587B (en) * 2022-04-10 2023-09-12 广州诗妃生物科技有限公司 Composition for rapidly guiding out comedones and preparation method thereof
CN118161412A (en) * 2024-04-08 2024-06-11 广州骏朗生物科技有限公司 Biological sun-screening agent with anti-inflammatory and allergy-relieving substances

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