CN111343994B - 用于抑制血管生成素-样3 (ANGPTL3)的表达的RNAi剂和组合物以及使用方法 - Google Patents

用于抑制血管生成素-样3 (ANGPTL3)的表达的RNAi剂和组合物以及使用方法 Download PDF

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CN111343994B
CN111343994B CN201880073901.XA CN201880073901A CN111343994B CN 111343994 B CN111343994 B CN 111343994B CN 201880073901 A CN201880073901 A CN 201880073901A CN 111343994 B CN111343994 B CN 111343994B
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angptl3
rnai agent
seq
nucleotide sequence
nucleotides
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CN111343994A (zh
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李珍
朱锐
S.黄
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Arrowhead Pharmaceuticals Inc
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CN201880073901.XA 2017-09-14 2018-09-13 用于抑制血管生成素-样3 (ANGPTL3)的表达的RNAi剂和组合物以及使用方法 Active CN111343994B (zh)

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US201762558819P 2017-09-14 2017-09-14
US62/558,819 2017-09-14
US201762583919P 2017-11-09 2017-11-09
US62/583,919 2017-11-09
US201862651284P 2018-04-02 2018-04-02
US62/651,284 2018-04-02
US201862694976P 2018-07-07 2018-07-07
US62/694,976 2018-07-07
PCT/US2018/050848 WO2019055633A1 (en) 2017-09-14 2018-09-13 RNAI AGENTS AND COMPOSITIONS FOR INHIBITING ANALOGUE EXPRESSION OF ANGIOPOIETIN 3 (ANGPTL3) AND METHODS OF USE

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