CN111325121B - 一种核酸质谱数值处理方法 - Google Patents
一种核酸质谱数值处理方法 Download PDFInfo
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- CN111325121B CN111325121B CN202010084107.4A CN202010084107A CN111325121B CN 111325121 B CN111325121 B CN 111325121B CN 202010084107 A CN202010084107 A CN 202010084107A CN 111325121 B CN111325121 B CN 111325121B
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- 238000001819 mass spectrum Methods 0.000 title claims abstract description 51
- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 17
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- 238000003672 processing method Methods 0.000 title abstract description 7
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- 238000012897 Levenberg–Marquardt algorithm Methods 0.000 claims description 3
- 230000000873 masking effect Effects 0.000 claims description 2
- 239000002773 nucleotide Substances 0.000 abstract description 7
- 125000003729 nucleotide group Chemical group 0.000 abstract description 7
- 238000004949 mass spectrometry Methods 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 238000004364 calculation method Methods 0.000 description 2
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- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0027—Methods for using particle spectrometers
- H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F2218/00—Aspects of pattern recognition specially adapted for signal processing
- G06F2218/02—Preprocessing
- G06F2218/04—Denoising
- G06F2218/06—Denoising by applying a scale-space analysis, e.g. using wavelet analysis
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F2218/00—Aspects of pattern recognition specially adapted for signal processing
- G06F2218/08—Feature extraction
- G06F2218/10—Feature extraction by analysing the shape of a waveform, e.g. extracting parameters relating to peaks
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Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010084107.4A CN111325121B (zh) | 2020-02-10 | 2020-02-10 | 一种核酸质谱数值处理方法 |
| PCT/CN2020/134810 WO2021159833A1 (zh) | 2020-02-10 | 2020-12-09 | 一种核酸质谱数值处理方法 |
| US17/771,216 US20220383979A1 (en) | 2020-02-10 | 2020-12-09 | Nucleic acid mass spectrum numerical processing method |
| EP20918621.2A EP4016379B1 (en) | 2020-02-10 | 2020-12-09 | Nucleic acid mass spectrum numerical processing method |
| JP2022535644A JP7456665B2 (ja) | 2020-02-10 | 2020-12-09 | 核酸マススペクトル数値処理方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010084107.4A CN111325121B (zh) | 2020-02-10 | 2020-02-10 | 一种核酸质谱数值处理方法 |
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| Publication Number | Publication Date |
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| CN111325121A CN111325121A (zh) | 2020-06-23 |
| CN111325121B true CN111325121B (zh) | 2024-02-20 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202010084107.4A Active CN111325121B (zh) | 2020-02-10 | 2020-02-10 | 一种核酸质谱数值处理方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220383979A1 (ja) |
| EP (1) | EP4016379B1 (ja) |
| JP (1) | JP7456665B2 (ja) |
| CN (1) | CN111325121B (ja) |
| WO (1) | WO2021159833A1 (ja) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111325121B (zh) * | 2020-02-10 | 2024-02-20 | 浙江迪谱诊断技术有限公司 | 一种核酸质谱数值处理方法 |
| CN112444556B (zh) * | 2020-09-27 | 2021-12-03 | 浙江迪谱诊断技术有限公司 | 一种飞行时间核酸质谱参数确定方法 |
| CN112378986B (zh) * | 2021-01-18 | 2021-08-03 | 宁波华仪宁创智能科技有限公司 | 质谱分析方法 |
| CN112877412B (zh) * | 2021-02-05 | 2022-09-27 | 浙江迪谱诊断技术有限公司 | 一种检测核酸质谱设备性能的方法 |
| CN113659961B (zh) * | 2021-07-19 | 2024-01-30 | 广东迈能欣科技有限公司 | 一种应用于二氧化碳传感器的滤波算法 |
| CN114487073B (zh) * | 2021-12-27 | 2024-04-12 | 浙江迪谱诊断技术有限公司 | 一种飞行时间核酸质谱数据校准方法 |
| CN114023379B (zh) * | 2021-12-31 | 2022-05-13 | 浙江迪谱诊断技术有限公司 | 一种确定基因型的方法及装置 |
Citations (11)
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| EP1469313A1 (en) * | 2001-12-08 | 2004-10-20 | Micromass UK Limited | Method of mass spectrometry |
| WO2012120300A1 (en) * | 2011-03-07 | 2012-09-13 | Micromass Uk Limited | Dynamic resolution correction of quadrupole mass analyser |
| CN105334279A (zh) * | 2014-08-14 | 2016-02-17 | 大连达硕信息技术有限公司 | 一种高分辨质谱数据的处理方法 |
| CN107533593A (zh) * | 2015-04-24 | 2018-01-02 | 生物梅里埃公司 | 用于通过质谱法从参考亚群的集合中鉴定未知微生物亚群的方法 |
| CN109145873A (zh) * | 2018-09-27 | 2019-01-04 | 广东工业大学 | 基于遗传算法的光谱高斯峰特征提取算法 |
| CN109416926A (zh) * | 2016-04-11 | 2019-03-01 | 迪森德克斯公司 | 质谱数据分析工作流程 |
| CN109632860A (zh) * | 2019-01-15 | 2019-04-16 | 中国科学院昆明植物研究所 | 一种解析混合物中单体化合物结构的方法 |
| CN109726667A (zh) * | 2018-12-25 | 2019-05-07 | 广州市锐博生物科技有限公司 | 质谱数据处理方法和装置、计算机设备、计算机存储介质 |
| WO2019150576A1 (ja) * | 2018-02-05 | 2019-08-08 | 株式会社島津製作所 | 質量分析装置及び質量分析装置における質量較正方法 |
| WO2019229869A1 (ja) * | 2018-05-30 | 2019-12-05 | 株式会社島津製作所 | スペクトルデータ処理装置及び分析装置 |
| CN114487072A (zh) * | 2021-12-27 | 2022-05-13 | 浙江迪谱诊断技术有限公司 | 一种飞行时间质谱峰拟合方法 |
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| US20030190644A1 (en) * | 1999-10-13 | 2003-10-09 | Andreas Braun | Methods for generating databases and databases for identifying polymorphic genetic markers |
| CA2684217C (en) | 2007-04-13 | 2016-12-13 | Sequenom, Inc. | Comparative sequence analysis processes and systems |
| EP2160570A4 (en) * | 2007-06-02 | 2012-12-05 | Cerno Bioscience Llc | SELF-CALIBRATION APPROACH FOR MASS SPECTROMETRY |
| DE102013006132B9 (de) * | 2013-04-10 | 2015-11-19 | Bruker Daltonik Gmbh | Hochdurchsatz-Charakterisierung von Proben durch Massenspektrometrie |
| CN107545213B (zh) * | 2016-06-28 | 2021-04-02 | 株式会社岛津制作所 | 基于飞行时间质谱的信号处理方法、系统及电子设备 |
| CN110196274B (zh) * | 2019-04-25 | 2022-02-08 | 上海裕达实业有限公司 | 可降低噪声的质谱装置及方法 |
| CN110441253A (zh) * | 2019-07-22 | 2019-11-12 | 杭州华聚复合材料有限公司 | 一种快速检测PP-g-MAH接枝率的方法 |
| CN111325121B (zh) * | 2020-02-10 | 2024-02-20 | 浙江迪谱诊断技术有限公司 | 一种核酸质谱数值处理方法 |
-
2020
- 2020-02-10 CN CN202010084107.4A patent/CN111325121B/zh active Active
- 2020-12-09 WO PCT/CN2020/134810 patent/WO2021159833A1/zh unknown
- 2020-12-09 JP JP2022535644A patent/JP7456665B2/ja active Active
- 2020-12-09 EP EP20918621.2A patent/EP4016379B1/en active Active
- 2020-12-09 US US17/771,216 patent/US20220383979A1/en active Pending
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| WO2012120300A1 (en) * | 2011-03-07 | 2012-09-13 | Micromass Uk Limited | Dynamic resolution correction of quadrupole mass analyser |
| CN105334279A (zh) * | 2014-08-14 | 2016-02-17 | 大连达硕信息技术有限公司 | 一种高分辨质谱数据的处理方法 |
| CN107533593A (zh) * | 2015-04-24 | 2018-01-02 | 生物梅里埃公司 | 用于通过质谱法从参考亚群的集合中鉴定未知微生物亚群的方法 |
| CN109416926A (zh) * | 2016-04-11 | 2019-03-01 | 迪森德克斯公司 | 质谱数据分析工作流程 |
| WO2019150576A1 (ja) * | 2018-02-05 | 2019-08-08 | 株式会社島津製作所 | 質量分析装置及び質量分析装置における質量較正方法 |
| WO2019229869A1 (ja) * | 2018-05-30 | 2019-12-05 | 株式会社島津製作所 | スペクトルデータ処理装置及び分析装置 |
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Also Published As
| Publication number | Publication date |
|---|---|
| EP4016379C0 (en) | 2024-01-31 |
| CN111325121A (zh) | 2020-06-23 |
| WO2021159833A1 (zh) | 2021-08-19 |
| US20220383979A1 (en) | 2022-12-01 |
| JP2023515296A (ja) | 2023-04-13 |
| JP7456665B2 (ja) | 2024-03-27 |
| EP4016379B1 (en) | 2024-01-31 |
| EP4016379A1 (en) | 2022-06-22 |
| EP4016379A4 (en) | 2022-12-14 |
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