CN111315388A - 聚糖制剂和用于高氨血症的使用方法 - Google Patents

聚糖制剂和用于高氨血症的使用方法 Download PDF

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Publication number
CN111315388A
CN111315388A CN201880071679.XA CN201880071679A CN111315388A CN 111315388 A CN111315388 A CN 111315388A CN 201880071679 A CN201880071679 A CN 201880071679A CN 111315388 A CN111315388 A CN 111315388A
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China
Prior art keywords
glycan
formulation
subject
deficiency
mol
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CN201880071679.XA
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English (en)
Chinese (zh)
Inventor
M.K.吉布森
N.W.斯特宾斯
R.蒂尔罗夫-埃克尔特
G.A.冯马尔特扎
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Dalishen Capital Co ltd
Dsm Nutritional Products Co ltd
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Kaleido Biosciences Inc
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Publication of CN111315388A publication Critical patent/CN111315388A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201880071679.XA 2017-11-03 2018-11-03 聚糖制剂和用于高氨血症的使用方法 Pending CN111315388A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762581583P 2017-11-03 2017-11-03
US62/581,583 2017-11-03
US201862673754P 2018-05-18 2018-05-18
US62/673,754 2018-05-18
US201862720924P 2018-08-21 2018-08-21
US62/720,924 2018-08-21
PCT/US2018/059102 WO2019090182A2 (en) 2017-11-03 2018-11-03 Glycan preparations and methods of use for hyperammonemia

Publications (1)

Publication Number Publication Date
CN111315388A true CN111315388A (zh) 2020-06-19

Family

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Family Applications (1)

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CN201880071679.XA Pending CN111315388A (zh) 2017-11-03 2018-11-03 聚糖制剂和用于高氨血症的使用方法

Country Status (5)

Country Link
US (1) US12090168B2 (https=)
EP (1) EP3703705B1 (https=)
JP (1) JP7576375B2 (https=)
CN (1) CN111315388A (https=)
WO (1) WO2019090182A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112048576A (zh) * 2020-08-03 2020-12-08 徐州工程学院 一种固体酸水解牛蒡制备果糖的方法
CN112326639A (zh) * 2020-11-25 2021-02-05 迈克生物股份有限公司 检测果糖胺的试剂盒和方法

Families Citing this family (9)

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Publication number Priority date Publication date Assignee Title
HK1246600B (en) 2015-01-26 2020-04-09 Cadena Bio, Inc. Oligosaccharide compositions for use animal feed and methods of producing thereof
EP3841127A2 (en) 2018-08-21 2021-06-30 Kaleido Biosciences, Inc. Oligosaccharide compositions and methods of use thereof for reducing ammonia levels
US11592891B2 (en) * 2019-10-15 2023-02-28 Dell Products L.P. System and method for diagnosing resistive shorts in an information handling system
US11896603B2 (en) * 2020-06-12 2024-02-13 The Regents Of The University Of California Oligosaccharide as therapeutic agent for alcohol associated liver disease
US12508274B2 (en) 2020-07-17 2025-12-30 Dsm Nutritional Products, Llc Oligosaccharide compositions and methods of use
AU2021350104A1 (en) * 2020-09-25 2023-06-08 Dsm Nutritional Products, Llc Oligosaccharide compositions and methods of use
JP2024030913A (ja) * 2022-08-25 2024-03-07 協同乳業株式会社 中高齢の対象の認知的柔軟性を高めるための組成物および組合せ
EP4649317A2 (en) * 2023-01-12 2025-11-19 Population Bio, Inc. Methods and compositions for screening and treating alzheimer's disease
CN116270603B (zh) * 2023-03-24 2024-08-06 黑龙江八一农垦大学 一种大豆苷元在制备用于缓解冷应激导致的肝损伤的药物中的应用

Citations (2)

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Cited By (3)

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Publication number Priority date Publication date Assignee Title
CN112048576A (zh) * 2020-08-03 2020-12-08 徐州工程学院 一种固体酸水解牛蒡制备果糖的方法
CN112326639A (zh) * 2020-11-25 2021-02-05 迈克生物股份有限公司 检测果糖胺的试剂盒和方法
CN112326639B (zh) * 2020-11-25 2024-01-05 迈克生物股份有限公司 检测果糖胺的试剂盒和方法

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US20220233577A1 (en) 2022-07-28
EP3703705A2 (en) 2020-09-09
EP3703705B1 (en) 2024-05-15
US12090168B2 (en) 2024-09-17
WO2019090182A2 (en) 2019-05-09
JP2021502339A (ja) 2021-01-28
JP7576375B2 (ja) 2024-10-31
WO2019090182A3 (en) 2019-06-06

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